MCID: MTN002
MIFTS: 33

Mite Infestation

Categories: Infectious diseases

Aliases & Classifications for Mite Infestation

MalaCards integrated aliases for Mite Infestation:

Name: Mite Infestation 12 14
Mite Infestations 41 69

Classifications:



External Ids:

Disease Ontology 12 DOID:7894
ICD10 32 B88.0 B88.9
ICD9CM 34 133 133.9
MeSH 41 D008924
UMLS 69 C0026229

Summaries for Mite Infestation

Disease Ontology : 12 A parasitic ectoparasitic infectious disease that involves infestation of mites belonging to the family Sarcoptidae, Trombiculidae and Demodicidae.

MalaCards based summary : Mite Infestation, also known as mite infestations, is related to parasitic ectoparasitic infectious disease and scabies. An important gene associated with Mite Infestation is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator). The drugs Ivermectin and Permethrin have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and t cells.

Related Diseases for Mite Infestation

Graphical network of the top 20 diseases related to Mite Infestation:



Diseases related to Mite Infestation

Symptoms & Phenotypes for Mite Infestation

Drugs & Therapeutics for Mite Infestation

Drugs for Mite Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ivermectin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 70288-86-7 46936176 6474909
2
Permethrin Approved, Investigational Phase 4,Phase 3,Phase 2 52645-53-1 40326
3
Azithromycin Approved Phase 4 83905-01-5 53477736 447043 55185
4 Anti-Infective Agents Phase 4,Phase 3,Phase 2
5 Antiparasitic Agents Phase 4,Phase 3,Phase 2
6
Malathion Approved, Investigational Phase 3 121-75-5 4004
7 Cholinergic Agents Phase 3
8 Cholinesterase Inhibitors Phase 3
9 Neurotransmitter Agents Phase 3
10 Dermatologic Agents Phase 3
11 Emollients Phase 3
12
Ethanol Approved Phase 2 64-17-5 702
13
Benzyl alcohol Approved Phase 2 100-51-6 244
14 Central Nervous System Depressants Phase 2
15 Anesthetics Phase 2
16 Anesthetics, Local Phase 2
17 Peripheral Nervous System Agents Phase 2
18 Pharmaceutical Solutions Phase 2
19
Diethylcarbamazine Approved, Investigational, Vet_approved 90-89-1 3052
20
Albendazole Approved, Vet_approved 54965-21-8 2082
21 Anthelmintics
22 Antimitotic Agents
23 Liver Extracts
24 Lipoxygenase Inhibitors
25 Antiprotozoal Agents

Interventional clinical trials:

(show all 21)

# Name Status NCT ID Phase Drugs
1 Azithromycin - Ivermectin Mass Drug Administration for Skin Disease Active, not recruiting NCT02775617 Phase 4 Ivermectin;Azithromycin;Permethrin
2 P3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02062060 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
3 Phase 3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02060903 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
4 Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies. Completed NCT02978508 Phase 3 Permethrin Cream, 5%;Elimite
5 A Study to Evaluate the Therapeutic Equivalence of Generic Permethrin Cream 5% to Elimite® in the Treatment of Scabies Completed NCT02572986 Phase 3 Permethrin
6 Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies Recruiting NCT02485717 Phase 3 spinosad topical suspension, 0.9%
7 Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies Recruiting NCT02485704 Phase 3 spinosad topical suspension, 0.9%
8 Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children Recruiting NCT02407782 Phase 3 Ivermectin;Permethrin
9 Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% in the Treatment of Scabies Active, not recruiting NCT03178942 Phase 3 Permethrin;Elimite 5% Cream
10 Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands Active, not recruiting NCT03236168 Phase 3 Ivermectin;Permethrin 5%;Malathion Shampoo 0.5%
11 Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies Not yet recruiting NCT02841215 Phase 3 Ivermectin 200 µg/kg;Ivermectin 400 µg/kg
12 Ovicidal Efficacy and Safety of Abametapir Lotion 0.74% Administered for the Treatment of Head Lice Infestation Completed NCT02097485 Phase 2 Abametapir Lotion 0.74% w/w;Vehicle Lotion
13 Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation Completed NCT01907490 Phase 2 Ha44 Gel
14 A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies Completed NCT02094716 Phase 2 Permethrin Foam 4%;Permethrin Foam 5%;Vehicle Foam
15 Comparison of the Efficacy and Safety of Ivermectin to Permethrin Completed NCT00262418 Phase 2 Administration of ivermectin or permethrin
16 Veron Scabies Education and Eradication Program Completed NCT00604084 Ivermectin;Permethrin 5% lotion
17 Prevalence of RHD, Pyoderma and Scabies in Children in Fiji Completed NCT00284843
18 Streptococcal Infections in Fiji - Prevalence of Group A Streptococcal Pyoderma and Scabies in Infants in Fiji Completed NCT00436891
19 Evaluation of a Regional Healthy Skin Program in Remote Aboriginal Communities of Australia's Northern Territory Completed NCT00884728
20 Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji Recruiting NCT03177993 3 drug dose - IDA;3 drug dose - IDA with second dose of ivermectin;2 drug dose - DA
21 PCR Assay for Diagnosis of Sarcoptes Scabiei Active, not recruiting NCT02254564

Search NIH Clinical Center for Mite Infestation

Cochrane evidence based reviews: mite infestations

Genetic Tests for Mite Infestation

Anatomical Context for Mite Infestation

MalaCards organs/tissues related to Mite Infestation:

38
Skin, Liver, T Cells

Publications for Mite Infestation

Articles related to Mite Infestation:

(show top 50) (show all 81)
# Title Authors Year
1
Efficacy and safety of sarolaner in the treatment of canine ear mite infestation caused by Otodectes cynotis: a non-inferiority study. ( 29392787 )
2018
2
Incidence of fur mite infestation in laboratory rodents. ( 28615846 )
2017
3
Role of Demodex mite infestation in rosacea: A systematic review and meta-analysis. ( 28711190 )
2017
4
Physiological and Molecular Alterations Promoted by Schizotetranychus oryzae Mite Infestation in Rice Leaves. ( 26667653 )
2016
5
Megninia ginglymura feather mite infestation in a Hamburg poultry flock in the United Kingdom. ( 26914957 )
2016
6
Developing food-grade coatings for dry-cured hams to protect against ham mite infestation. ( 26624793 )
2016
7
Mange mite infestation in small ruminants in Ethiopia: Systematic review and meta-analysis. ( 26872931 )
2016
8
Intensively Cultivated Landscape and Varroa Mite Infestation Are Associated with Reduced Honey Bee Nutritional State. ( 27070422 )
2016
9
Pruritic dermatitis caused by bird mite infestation. ( 26919364 )
2016
10
Evidence-based veterinary dermatology: a review of published studies of treatments for Otodectes cynotis (ear mite) infestation in cats. ( 27324289 )
2016
11
KNEMIDOKOPTINID (EPIDERMOPTIDAE: KNEMIDOKOPTINAE) MITE INFESTATION IN WILD RED-CROWNED PARAKEETS (CYANORAMPHUS NOVAEZELANDIAE): CORRELATIONS BETWEEN MACROSCOPIC AND MICROSCOPIC FINDINGS. ( 25973626 )
2015
12
Dust mite infestation in cooking flour: experimental observations and practical recommendations. ( 26141033 )
2015
13
Blood-feeding ectoparasites as developmental stressors: Does corticosterone mediate effects of mite infestation on nestling growth, immunity and energy availability? ( 26055169 )
2015
14
ORIBATID MITE INFESTATION IN THE STORED CHINESE HERBAL MEDICINES. ( 26319834 )
2015
15
Case records of the Massachusetts General Hospital. Case 37-2014. A 35-year-old woman with suspected mite infestation. ( 25427115 )
2014
16
Detection of group 2 Dermatophagoides pteronyssinus allergen for environmental monitoring of dust mite infestation. ( 23612077 )
2013
17
The role of onion-associated fungi in bulb mite infestation and damage to onion seedlings. ( 24242868 )
2013
18
Susceptibility and physiological responses of Jatropha curcas accessions to broad mite infestation. ( 23456604 )
2013
19
Demodex mite infestation of unknown significance in a patient with rhinocerebral mucormycosis due to Apophysomyces elegans species complex. ( 23475907 )
2013
20
Severe ulceronecrotic dermatitis associated with mite infestation in the critically endangered Amargosa vole (Microtus californicus scirpensis). ( 23458565 )
2013
21
Genotypic variability and relationships between mite infestation levels, mite damage, grooming intensity, and removal of Varroa destructor mites in selected strains of worker honey bees (Apis mellifera L.). ( 22465569 )
2012
22
Demodex mite infestation in patients with and without rheumatoid arthritis. ( 22807020 )
2012
23
Bacillus oleronius and Demodex mite infestation in patients with chronic blepharitis. ( 22114987 )
2012
24
Dog ear mite infestation: a possible problem in public health system. ( 22808412 )
2011
25
CFTR-deficiency renders mice highly susceptible to cutaneous symptoms during mite infestation. ( 21135815 )
2011
26
Conditional mutualism between Allodynerus delphinalis (Hymenoptera: Vespidae) and Ensliniella parasitica (Astigmata: Winterschmidtiidae) may determine maximum parasitic mite infestation. ( 20388271 )
2010
27
Localized nasal cavity, sinus, and massive bilateral orbital involvement by human T cell leukemia virus 1 adult T cell lymphoma, with epidermal hypertrophy due to mite infestation. ( 21234251 )
2010
28
Ear mite infestation in four imported dogs from Thailand; a case report. ( 22808403 )
2010
29
Localized seborrhoeic dermatitis with hyperhidrosis due to mite infestation in an Iranian cross-breed ram. ( 19579943 )
2009
30
Dust mite infestation of flour samples. ( 19895625 )
2009
31
Scrub-itch mite infestation in the endangered bridled nailtail wallaby. ( 19673851 )
2009
32
Assessment of immune activation in mice before and after eradication of mite infestation. ( 19653944 )
2009
33
Use of selamectin for the treatment of psoroptic and sarcoptic mite infestation in rabbits. ( 17222235 )
2007
34
Images in clinical medicine. Bird-mite infestation. ( 16625011 )
2006
35
Efficacy of topical administration of eprinomectin for treatment of ear mite infestation in six rabbits. ( 16238814 )
2005
36
Some observations on the pharmacological properties of ivermectin during treatment of a mite infestation in mice. ( 12906401 )
2003
37
Induction of direct and indirect plant responses by jasmonic acid, low spider mite densities, or a combination of jasmonic acid treatment and spider mite infestation. ( 14969353 )
2003
38
Chigger mite infestation. ( 13130088 )
2003
39
Efficacy and safety of topical administration of selamectin for treatment of ear mite infestation in rabbits. ( 12906226 )
2003
40
Large-bodied Demodex mite infestation in 4 dogs. ( 12418521 )
2002
41
Feather mite infestation in a broiler breeder farm. ( 11808668 )
2001
42
New treatment for harvest mite infestation. ( 11231715 )
2001
43
Topical application of garlic reduces northern fowl mite infestation in laying hens. ( 11092328 )
2000
44
Focal epidemic of sarcoptid (Acarina: Sarcoptidae) mite infestation in an insular population of white-footed mice. ( 9701941 )
1998
45
The role of mattress bases in the mite infestation of dwellings. ( 9042056 )
1997
46
Evaluation of the monitoring of papular dermatitis lesions in slaughtered swine to assess sarcoptic mite infestation. ( 8638387 )
1996
47
Treatment of sarcoptic mite infestation and mite hypersensitivity in pigs with injectable doramectin. ( 8735539 )
1996
48
Sarcoptic mange and production performance of swine: a review of the literature and studies of associations between mite infestation, growth rate and measures of mange severity in growing pigs. ( 8747908 )
1995
49
Rabbit mite infestation. ( 8017022 )
1994
50
Diagnostic exercise: mite infestation in a laboratory rat colony. ( 8028281 )
1994

Variations for Mite Infestation

Expression for Mite Infestation

Search GEO for disease gene expression data for Mite Infestation.

Pathways for Mite Infestation

GO Terms for Mite Infestation

Cellular components related to Mite Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 azurophil granule lumen GO:0035578 8.62 DEFA1 DEFA3

Biological processes related to Mite Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 antimicrobial humoral response GO:0019730 9.43 DEFA1 DEFA3
2 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.4 DEFA1 DEFA3
3 killing of cells of other organism GO:0031640 9.37 DEFA1 DEFA3
4 defense response to virus GO:0051607 9.33 DEFA1 DEFA3 UNC93B1
5 antibacterial humoral response GO:0019731 9.32 DEFA1 DEFA3
6 defense response to fungus GO:0050832 9.26 DEFA1 DEFA3
7 innate immune response in mucosa GO:0002227 8.96 DEFA1 DEFA3
8 intracellular estrogen receptor signaling pathway GO:0030520 8.62 DEFA1 DEFA3

Molecular functions related to Mite Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 8.92 CD79A DEFA3 DSCAML1 FLNA

Sources for Mite Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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