MELAS
MCID: MTC114
MIFTS: 53

Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS) malady

Categories: Genetic diseases, Rare diseases, Neuronal diseases, Eye diseases, Ear diseases, Metabolic diseases, Fetal diseases, Muscle diseases

Aliases & Classifications for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

About this section

Aliases & Descriptions for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:

Name: Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 52 11 25 35
Melas Syndrome 11 48 25 39 13 68
Melas 23 48 24 25 54 70
Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes 24 25
Myopathy, Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke 24 25
Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-Like Episodes Syndrome 70
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis and Stroke-Like Episodes 54
 
Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes 54
Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes 48
Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode 25
Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke 23
Lactic Acidosis,stroke-Like Episodes; Myopathy 23
Mitochondrial Encephalomyopathies 68
Mitochondrial Encephalomyopathy 23

Characteristics:

Orphanet epidemiological data:

54
melas:
Inheritance: Mitochondrial inheritance,Not applicable; Prevalence: 1-9/1000000 (Japan),1-9/1000000 (Europe),1-5/10000 (Finland),>1/1000; Age of onset: Adolescent,Adult,Childhood; Age of death: adolescent,adult,elderly,late childhood,young Adult

HPO:

64
mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes:
Inheritance: mitochondrial inheritance
Onset and clinical course: variable expressivity
Mortality/Aging: death in early adulthood

GeneReviews:

23
Penetrance: in mtdna-related disorders, penetrance typically depends on mutational load and tissue distribution, which show random variation within families (see genotype-phenotype correlations)...


Classifications:



External Ids:

OMIM52 540000
Disease Ontology11 DOID:3687
ICD1030 E88.41
MeSH39 D017241
NCIt45 C84885
SNOMED-CT62 240097009, 39925003
Orphanet54 ORPHA550
MESH via Orphanet40 D017241
ICD10 via Orphanet31 G71.3
UMLS via Orphanet69 C0162671
MedGen37 C0162671

Summaries for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

About this section
NIH Rare Diseases:48 Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (melas) affects many parts of the body, particularly the brain and nervous system (encephalo-) and muscles (myopathy). symptoms typically begin in childhood and may include muscle weakness and pain, recurrent headaches, loss of appetite, vomiting, and seizures. most affected individuals experience stroke-like episodes beginning before age 40. people with melas can also have a buildup of lactic acid in their bodies that can lead to vomiting, abdominal pain, fatigue, muscle weakness, and difficulty breathing. the genes associated with melas are located in mitochondrial dna and therefore follow a maternal inheritance pattern (also called mitochondrial inheritance). melas can be inherited from the mother only, because only females pass mitochondrial dna to their children. in some cases, melas results from a new mutation that was not inherited from a person's mother. last updated: 12/3/2013

MalaCards based summary: Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes, also known as melas syndrome, is related to mitochondrial encephalomyopathy and merrf/melas overlap syndrome, and has symptoms including hemiparesis, ophthalmoplegia and Array. An important gene associated with Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes is MT-ND4 (Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 4), and among its related pathways are GABAergic synapse and TP53 Regulates Metabolic Genes. Affiliated tissues include brain, heart and skin.

UniProtKB/Swiss-Prot:70 Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome: Genetically heterogeneous disorder, characterized by episodic vomiting, seizures, and recurrent cerebral insults resembling strokes and causing hemiparesis, hemianopsia, or cortical blindness.

Genetics Home Reference:25 Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a condition that affects many of the body's systems, particularly the brain and nervous system (encephalo-) and muscles (myopathy). The signs and symptoms of this disorder most often appear in childhood following a period of normal development, although they can begin at any age. Early symptoms may include muscle weakness and pain, recurrent headaches, loss of appetite, vomiting, and seizures. Most affected individuals experience stroke-like episodes beginning before age 40. These episodes often involve temporary muscle weakness on one side of the body (hemiparesis), altered consciousness, vision abnormalities, seizures, and severe headaches resembling migraines. Repeated stroke-like episodes can progressively damage the brain, leading to vision loss, problems with movement, and a loss of intellectual function (dementia).

OMIM:52 MELAS syndrome, comprising mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes, is a... (540000) more...

GeneReviews for NBK1233

Related Diseases for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

About this section

Diseases related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 60)
idRelated DiseaseScoreTop Affiliating Genes
1mitochondrial encephalomyopathy12.4
2merrf/melas overlap syndrome11.9
3fastkd2-related infantile mitochondrial encephalomyopathy11.9
4mitochondrial disorders11.9
5melas, mt-nd1-related11.7
6melas, mt-nd5-related11.7
7melas, mt-nd6-related11.7
8melas, mt-tf-related11.7
9melas, mt-tk-related11.7
10melas, mt-tl1-related11.7
11melas, mt-tq-related11.7
12melas, mt-ts1-related11.7
13melas, mt-ts2-related11.7
14melas, mt-th-related11.7
15encephalomyopathy11.5
16combined oxidative phosphorylation deficiency 611.2
17mitochondrial dna depletion syndrome 510.9
18lactic acidosis10.9
19myopathy10.9
20encephalopathy10.9
21mitochondrial complex i deficiency10.9
22lentigo maligna melanoma10.3MT-ND1, MT-ND4, MT-ND6
23dsg2-related dilated cardiomyopathy10.3MT-TK, MT-TL1
24undifferentiated carcinoma of the corpus uteri10.3MT-TL1, MT-TS1
25hyperthyroxinemia, familial dysalbuminemic10.3MT-CO1, MT-CO3
26parkinson disease 6, early onset10.3MT-ND5, MT-ND6
27mental retardation, obesity, mandibular prognathism, and eye and skin anomalies10.3MT-TK, MT-TL1
28adenylosuccinase deficiency10.3MT-CO1, MT-ND4, MT-TS1
29angiostrongyliasis10.3MT-CO1, MT-ND1
30plp1-related disorders10.3MT-CO1, MT-TS1
31histoplasmosis retinitis10.3MT-CO1, MT-ND4, MT-TW
32allergic contact dermatitis of eyelid10.3MT-ND1, MT-ND4, MT-ND5, MT-ND6
33deafness, autosomal recessive 10110.3MAPT, RPS27A
34severe congenital nemaline myopathy10.3MAPT, RPS27A
35non-functioning pituitary adenoma10.2MT-CO1, MT-TH, MT-TS1
36penis sarcoma10.2MT-CO3, MT-ND1
37oculoauricular syndrome10.2MT-CO1, MT-TC, MT-TH
38carotid body cancer10.2MT-ND1, MT-ND4, MT-ND5, MT-ND6
39autoimmune interstitial lung, joint, and kidney disease10.2MT-ND1, MT-ND4, MT-ND5, MT-ND6
40mucinous intrahepatic cholangiocarcinoma10.2MT-ND4, MT-ND5, MT-ND6, MT-TK
41syphilitic encephalitis10.2MT-CO1, MT-ND5, MT-TL1, MT-TS2
42enteropathica10.2MT-CO3, MT-ND1, MT-ND4, MT-ND5, MT-ND6
43meningoencephalitis10.2
44status epilepticus10.2
45intestinal pseudo-obstruction10.2
46growth hormone deficiency10.2
47nerve fibre bundle defect10.2MT-ND1, MT-ND4, MT-ND5, MT-ND6, MT-TK
48hemochromatosis, type 2a10.2MAPT, MT-ND1, RPS27A
49mitochondrial dna depletion syndrome 14, cardioencephalomyopathic type10.1MAPT, MT-ND1
50familial cold-induced inflammatory syndrome 110.1MT-CO1, MT-CO2, MT-CO3, MT-TL1, MT-TS1

Graphical network of the top 20 diseases related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:



Diseases related to mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes

Symptoms & Phenotypes for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

About this section

Symptoms by clinical synopsis from OMIM:

540000

Clinical features from OMIM:

540000

Human phenotypes related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:

 54 64 (show all 132)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 renal insufficiency64 54 Occasional (29-5%) HP:0000083
2 abnormality of the renal tubule54 Occasional (29-5%)
3 proteinuria64 54 Occasional (29-5%) HP:0000093
4 nephrotic syndrome64 54 Occasional (29-5%) HP:0000100
5 abnormality of the teeth54 Occasional (29-5%)
6 gingival overgrowth64 54 Occasional (29-5%) HP:0000212
7 microcephaly64 54 Occasional (29-5%) HP:0000252
8 mask-like facies64 54 Occasional (29-5%) HP:0000298
9 hypertelorism64 54 Occasional (29-5%) HP:0000316
10 abnormality of the pinna54 Frequent (79-30%)
11 sensorineural hearing impairment64 54 Frequent (79-30%) HP:0000407
12 protruding ear64 54 Occasional (29-5%) HP:0000411
13 visual impairment64 54 Occasional (29-5%) HP:0000505
14 ptosis64 54 Frequent (79-30%) HP:0000508
15 cataract64 54 Occasional (29-5%) HP:0000518
16 ophthalmoparesis64 54 Occasional (29-5%) HP:0000597
17 optic atrophy64 54 Occasional (29-5%) HP:0000648
18 abnormality of visual evoked potentials64 54 Occasional (29-5%) HP:0000649
19 night blindness54 Occasional (29-5%)
20 carious teeth64 54 Occasional (29-5%) HP:0000670
21 depression64 54 Frequent (79-30%) HP:0000716
22 autism64 54 Occasional (29-5%) HP:0000717
23 psychotic episodes64 54 Occasional (29-5%) HP:0000725
24 hallucinations64 54 Frequent (79-30%) HP:0000738
25 anxiety64 54 Frequent (79-30%) HP:0000739
26 decreased nerve conduction velocity64 54 Frequent (79-30%) HP:0000762
27 hypothyroidism64 54 Occasional (29-5%) HP:0000821
28 hypertension64 54 Occasional (29-5%) HP:0000822
29 delayed puberty64 54 Occasional (29-5%) HP:0000823
30 hypoparathyroidism64 54 Occasional (29-5%) HP:0000829
31 anterior hypopituitarism64 54 Occasional (29-5%) HP:0000830
32 hyperthyroidism64 54 Occasional (29-5%) HP:0000836
33 goiter64 54 Occasional (29-5%) HP:0000853
34 multiple lipomas64 54 Occasional (29-5%) HP:0001012
35 hypopigmented skin patches64 54 Occasional (29-5%) HP:0001053
36 abnormality of the macula64 54 Occasional (29-5%) HP:0001103
37 visual field defect54 Frequent (79-30%)
38 seizures54 Very frequent (99-80%)
39 ataxia64 54 Frequent (79-30%) HP:0001251
40 muscular hypotonia64 54 Occasional (29-5%) HP:0001252
41 dysarthria64 54 Occasional (29-5%) HP:0001260
42 reduced tendon reflexes64 54 Occasional (29-5%) HP:0001315
43 muscle weakness64 54 Very frequent (99-80%) HP:0001324
44 dystonia64 54 Occasional (29-5%) HP:0001332
45 tremor64 54 Occasional (29-5%) HP:0001337
46 congestive heart failure64 54 Occasional (29-5%) HP:0001635
47 hypertrophic cardiomyopathy64 54 Occasional (29-5%) HP:0001639
48 sudden cardiac death64 54 Occasional (29-5%) HP:0001645
49 wolff-parkinson-white syndrome64 54 Occasional (29-5%) HP:0001716
50 aortic dilatation64 54 Occasional (29-5%) HP:0001724
51 pancreatitis64 54 Frequent (79-30%) HP:0001733
52 fever64 54 Occasional (29-5%) HP:0001945
53 tubulointerstitial abnormality64 54 Occasional (29-5%) HP:0001969
54 nausea and vomiting64 54 Frequent (79-30%) HP:0002017
55 constipation64 54 Occasional (29-5%) HP:0002019
56 malabsorption64 54 Occasional (29-5%) HP:0002024
57 abdominal pain64 54 Frequent (79-30%) HP:0002027
58 anorexia64 54 Frequent (79-30%) HP:0002039
59 generalized tonic-clonic seizures64 54 Very frequent (99-80%) HP:0002069
60 migraine64 54 Very frequent (99-80%) HP:0002076
61 pulmonary hypertension54 Occasional (29-5%)
62 respiratory insufficiency64 54 Frequent (79-30%) HP:0002093
63 apnea64 54 Occasional (29-5%) HP:0002104
64 ventriculomegaly64 54 Occasional (29-5%) HP:0002119
65 cerebral cortical atrophy64 54 Frequent (79-30%) HP:0002120
66 hypercalciuria64 54 Occasional (29-5%) HP:0002150
67 increased serum lactate64 54 Very frequent (99-80%) HP:0002151
68 neurological speech impairment54 Occasional (29-5%)
69 clonus64 54 Frequent (79-30%) HP:0002169
70 pulmonary embolism64 54 Occasional (29-5%) HP:0002204
71 generalized hirsutism64 54 Occasional (29-5%) HP:0002230
72 abnormality of neuronal migration64 54 Occasional (29-5%) HP:0002269
73 eeg abnormality64 54 Occasional (29-5%) HP:0002353
74 memory impairment64 54 Frequent (79-30%) HP:0002354
75 developmental regression64 54 Very frequent (99-80%) HP:0002376
76 aphasia64 54 Occasional (29-5%) HP:0002381
77 stroke-like episodes64 54 Occasional (29-5%) HP:0002401
78 cerebral calcification64 54 Frequent (79-30%) HP:0002514
79 gastroparesis64 54 Occasional (29-5%) HP:0002578
80 cerebral ischemia64 54 Very frequent (99-80%) HP:0002637
81 aortic dissection64 54 Occasional (29-5%) HP:0002647
82 delayed skeletal maturation64 54 Occasional (29-5%) HP:0002750
83 arthrogryposis multiplex congenita64 54 Occasional (29-5%) HP:0002804
84 lactic acidosis64 54 Very frequent (99-80%) HP:0003128
85 ragged-red muscle fibers64 54 Very frequent (99-80%) HP:0003200
86 skeletal muscle atrophy64 54 Occasional (29-5%) HP:0003202
87 elevated serum creatine phosphokinase64 54 Very frequent (99-80%) HP:0003236
88 abnormality of mitochondrial metabolism64 54 Very frequent (99-80%) HP:0003287
89 myalgia64 54 Occasional (29-5%) HP:0003326
90 paresthesia64 54 Occasional (29-5%) HP:0003401
91 emg abnormality64 54 Very frequent (99-80%) HP:0003457
92 mitochondrial myopathy64 54 Very frequent (99-80%) HP:0003737
93 short stature64 54 Frequent (79-30%) HP:0004322
94 cachexia64 54 Frequent (79-30%) HP:0004326
95 reduced consciousness/confusion64 54 Frequent (79-30%) HP:0004372
96 intestinal obstruction64 54 Occasional (29-5%) HP:0005214
97 type ii diabetes mellitus64 54 Frequent (79-30%) HP:0005978
98 attention deficit hyperactivity disorder64 54 Frequent (79-30%) HP:0007018
99 aplasia/hypoplasia of the cerebellum64 54 Frequent (79-30%) HP:0007360
100 spontaneous hematomas64 54 Occasional (29-5%) HP:0007420
101 abnormality of retinal pigmentation64 54 Occasional (29-5%) HP:0007703
102 ichthyosis64 54 Occasional (29-5%) HP:0008064
103 primary adrenal insufficiency64 54 Occasional (29-5%) HP:0008207
104 feeding difficulties in infancy64 54 Occasional (29-5%) HP:0008872
105 peripheral neuropathy54 Occasional (29-5%)
106 abnormality of immune system physiology54 Occasional (29-5%)
107 arrhythmia54 Occasional (29-5%)
108 hemianopsia54 Frequent (79-30%)
109 fatigue64 54 Very frequent (99-80%) HP:0012378
110 heart block64 54 Occasional (29-5%) HP:0012722
111 cognitive impairment54 Frequent (79-30%)
112 amaurosis fugax64 54 Occasional (29-5%) HP:0100576
113 death in early adulthood54 Very frequent (99-80%)
114 thyroiditis64 54 Occasional (29-5%) HP:0100646
115 type i diabetes mellitus64 54 Occasional (29-5%) HP:0100651
116 glomerulopathy64 54 Occasional (29-5%) HP:0100820
117 progressive sensorineural hearing impairment64 HP:0000408
118 congenital cataract64 HP:0000519
119 ophthalmoplegia64 HP:0000602
120 dementia64 HP:0000726
121 diabetes mellitus64 HP:0000819
122 hemiparesis64 HP:0001269
123 encephalopathy64 HP:0001298
124 growth abnormality64 HP:0001507
125 left ventricular hypertrophy64 HP:0001712
126 episodic vomiting64 HP:0002572
127 myopathy64 HP:0003198
128 bilateral sensorineural hearing impairment64 HP:0008619
129 hemianopia64 HP:0012377
130 cortical visual impairment64 HP:0100704
131 nyctalopia64 HP:0000662
132 pulmonary arterial hypertension64 HP:0002092

UMLS symptoms related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:


hemiparesis, ophthalmoplegia

Drugs & Therapeutics for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

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Drugs for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 73)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Melatoninapproved, nutraceutical, vet_approvedPhase 4, Phase 2, Phase 326873-31-4896
Synonyms:
0E2B08C1-B325-45B1-8939-6F9081EFDFA4
4-ACETAMIDO-4'-ISOTHIO-CYANATOSTILBENE-2,2'-DISULFONIC ACID
5-22-12-00042 (Beilstein Handbook Reference)
5-Methoxy-N-acetyltryptamine
5-methoxy-N-acetyltryptamine
73-31-4
A4039/0172195
AB00053279
AC1L1A9Q
AC1Q4F1W
AC1Q4F1X
AKOS000276269
Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)- (9CI)
Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI)
Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI)
Acetamide, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-}
Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-}
BAS 01281092
BIDD:ER0618
BPBio1_000590
BRD-K97530723-001-07-6
BRN 0205542
BSPBio_000536
BSPBio_003006
Bio-0635
C01598
CAS-73-31-4
CCRIS 3472
CHEBI:16796
CHEMBL45
CID896
ChemDiv2_003916
Circadin
D008550
D08170
DB01065
DB08189
DivK1c_000353
EINECS 200-797-7
EU-0100787
HMS1380B22
HMS1569K18
HMS1921E04
HMS2089F09
HMS501B15
HSCI1_000400
HSDB 7509
I05-0076
I10-0345
IDI1_000353
IDI1_002631
IN1244
KBio1_000353
KBio2_000665
KBio2_003233
KBio2_005801
KBio3_002226
KBioGR_000591
KBioSS_000665
L001261
LS-1623
Lopac-M-5250
Lopac0_000787
M 5250
M-1200
M-1250
M1105
M5250_SIGMA
ML1
MLS000859594
MLS001055382
MLS001240204
MT6
Mela-T
Melapure
Melatol
Melatonex
Melatonex, Melatonin
Melatonin
Melatonin (synth.) standard-grade
 
Melatonin (synth.) ultra-pure
Melatonina
Melatonina (TN)
Melatonine
Melovine
MolPort-000-737-883
N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)-Acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide
N-Acetyl-5-methoxy-tryptamine
N-Acetyl-5-methoxy-tryptamine Melatonine
N-Acetyl-5-methoxytryptamine
N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-Acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide
N-[2-(5-Methoxyindol-3-yl)ethyl]-Acetamide
N-[2-(5-Methoxyindol-3-yl)ethyl]acetamide
N-[2-(5-methoxyindol-3-yl)ethyl]acetamide
N-acetyl-5-methoxy-tryptamine
NCGC00015680-01
NCGC00015680-02
NCGC00015680-03
NCGC00015680-06
NCGC00015680-13
NCGC00090727-01
NCGC00090727-02
NCGC00090727-03
NCGC00090727-04
NCGC00090727-05
NCGC00090727-06
NCGC00090727-07
NCGC00090727-08
NCGC00090727-09
NCI60_004378
NINDS_000353
NMR/14327425
NSC 113928
NSC113928
NSC56423
Nature'S Harmony
Night Rest
Oprea1_104553
Oprea1_814234
PREVENTION 1 (MELATONIN) (PREVENTION 1)
PREVENTION 2 (MELATONIN)
PREVENTION 3 (MELATONIN)
PREVENTION 4 (MELATONIN)
PREVENTION 5 (MELATONIN)
Pineal Hormone
Posidorm
Prestwick0_000458
Prestwick1_000458
Prestwick2_000458
Prestwick3_000458
Prestwick_312
Regulin
Revital Melatonin
Rx Balance
S1204_Selleck
SDCCGMLS-0065812.P001
SDCCGMLS-0065812.P002
SMP2_000309
SMR000326666
SPBio_001527
SPBio_002475
SPECTRUM1500690
STK386880
Sleep Right
Spectrum2_001344
Spectrum3_001393
Spectrum4_000066
Spectrum5_001745
Spectrum_000185
TNP00300
UNII-JL5DK93RCL
Vivitas
WLN: T56 BMJ D2MV1 GO1
ZINC00057060
{N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-} Acetamide
{N-[2-(5-methoxyindol-3-yl)ethyl]-} Acetamide
2VaccinesPhase 46611
3AntioxidantsPhase 4, Phase 2, Phase 3, Early Phase 13050
4Protective AgentsPhase 4, Phase 2, Phase 3, Early Phase 17443
5Central Nervous System DepressantsPhase 4, Phase 2, Phase 3, Phase 113403
6
Folic Acidapproved, nutraceutical, vet_approvedPhase 2, Phase 3439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
7VitaminsPhase 2, Phase 35282
8Trace ElementsPhase 2, Phase 36001
9Vitamin B ComplexPhase 2, Phase 34337
10MicronutrientsPhase 2, Phase 36001
11InositolNutraceuticalPhase 2, Phase 387
12Vitamin B9NutraceuticalPhase 2, Phase 34392
13FolateNutraceuticalPhase 2, Phase 34392
14Idebenoneapproved, investigationalPhase 22158186-27-9
15
Cysteamineapproved, investigationalPhase 22760-23-16058
Synonyms:
(2-Mercaptoethyl)amine
(Mercaptoethyl)ammonium toluene-p-sulphonate
.beta.-Mercaptoethylamine
1-Amino-2-mercaptoethylamine
139720-70-0
156-57-0 (hydrochloride)
16904-32-8 (di-hydrochloride)
2-AMINO-ETHANETHIOL
2-AMINO-ethanethiol
2-Amino-1-ethanethiol
2-Aminoethanethiol
2-Aminoethyl mercaptan
2-Mercaptoethanamine
2-Mercaptoethylamine
2-Mercaptoethylamine, polymer-bound
27761-19-9 (tartrate (1:1))
2DFDA1F8-7010-4225-8280-AB1C4C43F546
30070_FLUKA
30070_SIGMA
3037-04-5
3037-04-5 (tosylate)
42954-15-4 (hydrobromide)
60-23-1
60-23-1 (Parent)
641022_ALDRICH
93965-19-6 (maleate (1:1))
A0648
AC1L1LPL
AC1Q54NL
AKOS003793343
Aminoethyl mercaptan
Becaptan
C-9500
C01678
C2H7NS
CASH
CCRIS 3083
CHEBI:17141
CHEMBL602
CID6058
CYSTEAMINE
Cisteamina
Cisteamina [Italian]
Cystavision
Cysteamide
Cysteamin
Cysteamine
Cysteamine (USAN)
Cysteamine [USAN:BAN]
Cysteamine bitartate
Cysteamine hydrochloride
Cysteaminium
Cysteinamine
D03634
DB00847
Decarboxycysteine
DivK1c_006750
 
EINECS 200-463-0
EINECS 221-235-7
Ethanethiolamine
HSDB 7353
KBio1_001694
KBio2_002235
KBio2_004803
KBio2_007371
KBioSS_002235
L 1573
L-1573
LS-65761
Lambraten
Lambratene
Lopac-M-6500
M9768_ALDRICH
M9768_SIGMA
MEA
MEA (mercaptan)
Mecramine
Mercamin
Mercamine
Mercaptamin
Mercaptamina
Mercaptamina [INN-Spanish]
Mercaptamine
Mercaptamine (INN)
Mercaptaminum
Mercaptaminum [INN-Latin]
Mercaptoethylamine
Merkamin
MolPort-001-662-635
NCGC00015691-01
NCGC00015691-04
NCGC00162236-01
NCI60_002000
NSC 647528
NSC647528
Riacon
STK315355
SpecPlus_000654
Spectrum_001755
Thioethanolamine
UNII-5UX2SD1KE2
WR 347
b-Aminoethanethiol
b-Aminoethylthiol
b-Mercaptoethylamine
beta-Aminoethanethiol
beta-Aminoethylthiol
beta-MEA
beta-Mercaptoethylamine
bmse000388
cysteamine bitartrate
nchembio.315-comp1
nchembio.316-comp1
β-MEA
β-aminoethylthiol
16UbiquinonePhase 2145
17arginineNutraceuticalPhase 2, Early Phase 1425
18
DonepezilapprovedPhase 1286120014-06-43152
Synonyms:
( inverted exclamation markA)-E 2020
1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine
120014-06-4
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one
AB1004836
AC-6969
AC1L1FAE
AKOS000277311
Aricept
Aricept ODT
C24H29NO3
CHEBI:53289
CHEMBL502
CID3152
D07869
DB00843
Domepezil
Donaz
Donaz (TN)
 
Donepezil
Donepezil (INN)
Donepezil [INN:BAN]
Donepezil hydrochloride
Donepezilo
Donepezilum
Eranz
I06-0343
KBio2_002144
KBio2_004712
KBio2_007280
KBioSS_002144
LS-81819
MolPort-000-881-588
MolPort-003-847-014
NCGC00167537-01
Oprea1_188452
Spectrum5_001662
Spectrum_001664
TL8000531
UNII-8SSC91326P
19
DopamineapprovedPhase 1383651-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
20
Furosemideapproved, vet_approvedPhase 119354-31-93440
Synonyms:
2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid
4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid
4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid
4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
41733-55-5 (mono-hydrochloride salt)
5-18-09-00555 (Beilstein Handbook Reference)
54-31-9
AB00052001
AC-11067
AC1L1FXW
AC1Q557O
AKOS000266625
ARONIS24304
Acetic acid potassium salt
Aisemide
Aldalix
Aldic
Aluzine
Anfuramaide
Apo-Frusemide
Apo-Furosemide
Aquarid
Aquasin
Arasemide
BIDD:GT0139
BPBio1_000443
BRD-K78010432-001-05-8
BRN 0840915
BSPBio_000401
BSPBio_002054
Beronald
Bio-0044
Bioretic
Bristab
Bristurin
C12H11ClN2O5S
CAS-54-31-9
CCRIS 1951
CHEBI:47426
CHEMBL35
CID3440
CPD000058202
Cetasix
Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure
Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure [German]
D00331
D005665
DB00695
DB07799
Depix
Desal
Desdemin
Di-Ademil
Dihydroflumethiazide
Dirine
Disal
Discoid
Disemide
Diucardin
Diumide-K
Diural
Diurapid
Diuretic Salt
Diuretic salt
Diurin
Diurolasa
Diusemide
Diusil
Diuzol
DivK1c_000575
Dranex
Dryptal
Durafurid
EINECS 200-203-6
Edemid
Edenol
Eliur
Elodrine
Endural
Errolon
Eutensin
F0182
F4381_SIGMA
FUN
FUROSEMIDE USP
Farsix
Finuret
Fluidrol
Fluss
Franyl
Frumex
Frumide
Frumil
Frusedan
Frusema
Frusemid
Frusemide
Frusemin
Frusenex
Frusetic
Frusid
Fu sid
Fulsix
Fuluvamide
Fuluvamine
Furanthril
Furanthryl
Furantral
Furantril
Furanturil
Furesis
Furetic
Furex
Furfan
Furix
Furmid
Furo-Basan
Furo-Puren
Furo-puren
Furobeta
Furocot
Furodiurol
Furodrix
Furomen
Furomex
Furomide M.D
Furomide M.D.
Furorese
Furosan
Furose
Furosedon
Furosemid
Furosemida
Furosemida [INN-Spanish]
Furosemide
Furosemide "mita"
Furosemide (JP15/USP/INN)
Furosemide Monohydrochloride
Furosemide Monosodium Salt
Furosemide [USAN:INN:JAN]
Furosemidu
Furosemidu [Polish]
Furosemidum
Furosemidum [INN-Latin]
Furosemix
Furoside
Furosifar
Furosix
Furoter
Furovite
Fursemid
Fursemida
Fursemide
Fursol
Fusid
Fusidic acid
 
Golan
HMS1569E03
HMS1920B03
HMS2090K06
HMS2091H05
HMS501M17
HSDB 3086
Hissuflux
Hoe-058A
Hydol
Hydrenox
Hydrex
Hydro
Hydro-Rapid
Hydro-rapid
Hydroled
I04-0179
IDI1_000575
Impugan
Jenafusid
KBio1_000575
KBio2_001580
KBio2_004148
KBio2_006716
KBio3_001274
KBioGR_001259
KBioSS_001580
Katlex
Kofuzon
Kolkin
Kutrix
LB 502
LB-502
LS-204
Lasemid
Lasex
Lasiletten
Lasilix
Lasix
Lasix (TN)
Lasix (tn)
Lasix Retard
Lasix Special
Lasix, Frusemide, Furosemide
Laxur
Lazix
Leodrine
Less Diur
Liside
Logirene
Lowpston
Lowpstron
Luscek
MLS001066374
MLS001306403
Macasirool
Marsemide
Metflorylthiazidine
Methforylthiazidine
Mirfat
Mita
Moilarorin
MolPort-001-641-065
Myrosemide
NCGC00016241-01
NCGC00090893-01
NCGC00090893-02
NCGC00090893-03
NCGC00090893-05
NCGC00090893-06
NCI-C55936
NINDS_000575
NSC 269420
NSC269420
Nadis
Nelsix
Neo-Renal
Neo-renal
Nephron
Nicorol
Novosemide
Octan Draselny
Octan draselny
Odemase
Odemex
Oedemex
Olmagran
Oprea1_667724
Osyrol
Polysquall A
Prefemin
Prestwick0_000341
Prestwick1_000341
Prestwick2_000341
Prestwick3_000341
Prestwick_752
Profemin
Promedes
Promide
Protargen
Puresis
Radisemide
Radonna
Radouna
Retep
Rodiuran
Rontyl
Rosemide
Rosis
Rusyde
S1603_Selleck
SAM002264614
SMP1_000129
SMR000058202
SPBio_001129
SPBio_002322
SPECTRUM1500310
STK177334
Sal Diureticum
Sal diureticum
Salinex
Salix
Salix (brand of furosemide)
Salurex
Salurid
Saluron
Seguril
Selectofur
Sigasalur
Sisuril
Spectrum2_001005
Spectrum3_000437
Spectrum4_000560
Spectrum5_000744
Spectrum_001100
Spirofur
Synephron
TL8003563
Transit
Trofurit
UNII-7LXU5N7ZO5
UPCMLD-DP022
UPCMLD-DP022:001
Uremide
Uresix
Urex
Urex-M
Urian
Uridon
Uritol
Urosemide
Vergonil
Vesix
WLN: T5OJ B1MR CG FVQ DSZW
Yidoli
Zafimida
fulvamide
furosemide
furosemide ''mita''
less Diur
21
OxazepamapprovedPhase 19604-75-14616
Synonyms:
(+-)-7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
(+-)-Oxazepam
(RS)-Oxazepam
1,3-Dihydro-7-chloro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
1,3-Dihydro-7-chloro-3-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one
35295-88-6
604-75-1
61036-43-9
7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-1,4(2H)-benzodiazepin-2-one
7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepine-2-one
7-Chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
AC1L1IKD
Abboxampam
Abboxapam
Adumbran
Alepam
Ansioxacepam
Anxiolit
Anxiolit retard
Aplakil
Apo-astress
Astress
Azutranguil
Azutranquil
Bonare
C07359
CB 8092
CCRIS 488
CHEBI:7823
CHEMBL568
CID4616
D00464
D010076
DB00842
DEA No. 2835
DF2371850
DivK1c_000986
Drimuel
Droxacepam
Durazepam
EINECS 210-076-9
Enidrel
HMS503E13
HSDB 3140
Hi-Long
Hilong
IDI1_000986
InChI=1/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)
Isodin
KBio1_000986
LS-34236
LS-44
Lederpam
Limbial
MolPort-001-729-110
Murelax
N-Desmethyltemazepam
 
NCGC00159323-02
NINDS_000986
NIOSH/DF2371850
NSC 169448
NSC169448
Nesontil
Noctazepam
Nortemazepam
Notaral
Nozepam
O5254_SIGMA
Oprea1_501459
Ossazepam
Ossazepam [DCIT]
Oxa-puren
Oxanid
Oxazepam (JAN/USP/INN)
Oxazepam [USAN:INN:BAN:JAN]
Oxazepamum
Oxazepamum [INN-Latin]
Oxazipam
Oxozepam
Pacienx
Praxiten
Propax
Psicopax
Psiquiwas
QUEN
Quilibrex
Ro 5-6789
Rondar
Sedigoa
Serax
Serax (TN)
Serenal
Serenid
Serenid-D
Serepax
Seresta
Serpax
Sigacalm
Sobril
Tacepam
Tarchomin
Tazepam
Tranquo-buscopan-wirkstoff
UNII-6GOW6DWN2A
Uskan
Vaben
WLN: T67 GMV JN IHJ CG IQ KR
WY-3498
Wy 3498
Wy-3498 stic
Z 10 tr
Z10-Tr
Zaxopam
d-Oxazepam hemisuccinate
nchembio747-comp28
oxazepam
p acienx
tranquo-buscopan- wirkstoff
22
RamiprilapprovedPhase 115287333-19-55362129
Synonyms:
(2 S ,3 aS ,6 aS )-1[( S )-N-[( S )-1-Carboxy-3-phenylpropyl] alanyl] octahydrocyclopenta [ b ]pyrrole-2-carboxylic acid, 1-ethyl ester
(2S,3aS,6aS)-1-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl) octahydrocyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, 1-ethyl ester
(2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure
(2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (non-preferred name)
(2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid.
(2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
(2s,3as,6as)-1((s)-n-((s)-1-carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic
(2s,3as,6as)-1-((s)-2-((s)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)-octahydrocyclopenta[b]p
(2s,3as,6as)-1-[(s)-2-((s)-1-ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]
126613-39-6
87333-19-5
AC-1347
AC1NSFPR
Acovil
Almirall Brand of Ramipril
Altace
Altace (TN)
Altace (tn)
Astra Brand of Ramipril
AstraZeneca Brand of Ramipril
Aventis Brand of Ramipril
Aventis Pharma Brand of Ramipril
BIDD:GT0803
BSPBio_003347
Bio-0651
C23H32N2O5
CHEBI:289203
CHEBI:8774
CHEMBL1168
CID5362129
CPD000466386
Carasel
Cardace
D00421
D017257
DB00178
Delix
HMS2051E04
HMS2090L11
HMS2093M10
HOE 498
HOE498
Hoe-498
Hoechst Brand of Ramipril
 
Hypren
Hytren
KBio2_002504
KBio2_005072
KBio2_007640
KBio3_002849
KBioGR_001858
KBioSS_002512
LS-58199
Lostapres
MLS000759523
MLS001216547
MLS001423965
MolPort-001-736-571
Monarch Brand of Ramipril
N-(1S-carboethoxy-3-phenylpropyl)-S-alanyl-cis,endo-2-azabicyclo[3.3.0]octane-3S-carboxylic Acid
NCGC00178127-01
Naprix
Pramace
Pramace (discontinued)
Promed Brand of Ramipril
Quark
R0404_SIGMA
Ramace
Ramipril
Ramipril (USP/INN)
Ramipril [USAN:INN:BAN]
Ramiprilum
Ramiprilum [Latin]
Ramipro, Tritace, Altace, Prilace, Ramipril
S1793_Selleck
SAM001246757
SAM002699899
SMR000466386
SPECTRUM1505214
STK801937
Spectrum3_001794
Spectrum4_001269
Spectrum5_001721
Spectrum_001958
Triatec
Tritace
UNII-L35JN3I7SJ
Unipril
Vesdil
Zabien
[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
[2s,3as,6as]-1-[(2s)-2-[[(1s)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopen
ramipril
23
ZopicloneapprovedPhase 12643200-80-25735
Synonyms:
(+-)-Zopiclone
(+-)-zopiclone
(±)-zopiclone
1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo(3,4-b)pyrazin-5-yl ester
1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
138680-07-6
27267 R.P
27267 R.P.
4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
4-Methyl-1-piperazinecarboxylic acid ester with 6-(5-chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo(3,4-b)pyrazin-5-one
43200-80-2
6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate
6-(5-chloro-2-pyridyl)-6,7-dihydro- 7-oxo-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methyl-1- piperazinecarboxylate
6-(5-chloropyrid-2-yl)-5-(4-methylpiperazin-1-yl)carbonyloxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
AC1L1L0T
AbZ brand of zopiclone
Aliud brand of zopiclone
Alpharma brand of zopiclone
Amoban
Amoban (TN)
Amovane
Aventis Pharma brand of zopiclone
Aventis brand of zopiclone
Azupharma brand of zopiclone
BPBio1_001146
BRD-A34309505-001-08-5
BRN 0768704
Bio-0528
Biomol-NT_000284
C17H17ClN6O3
C515050
CHEBI:32315
CHEBI:324263
CHEMBL135400
CID5735
Ciclum brand of zopiclone
Clonmel brand of zopiclone
D01372
DB01198
Dolorgeit brand of zopiclone
EINECS 256-138-9
EU-0101270
Gerard brand of zopiclone
Hexal brand of zopiclone
Hormosan brand of zopiclone
Imovance
Imovane
Italfarmaco brand of zopiclone
LS-110937
Limovan
Lopac0_001270
MLS000028547
MLS000083579
MLS001201837
MLS001304058
Merck dura brand of zopiclone
MolPort-002-507-850
NCGC00024993-03
NCGC00024993-04
Norton brand of zopiclone
 
Novo-zopiclone
Nu-Pharm brand of zopiclone
Nu-Zopiclone
Optidorm
Opus brand of zopiclone
Pinewood brand of zopiclone
RP 27 267
RP 27267
RP-27267
Ran-zopiclone
Ratiopharm brand of zopiclone
Rhodiapharm brand of zopiclone
Rhone-Poulenc Rorer brand of zopiclone
Rhovane
S1446_Selleck
SMR000048685
STK599439
Siaten
Sopivan
Stadapharm brand of zopiclone
TAD brand of zopiclone
Temmler brand of zopiclone
Teva brand of zopiclone
UNII-03A5ORL08Q
Ximovan
Z 4900
Z4900_SIGMA
Zileze
Zimoclone
Zimovane
Zopi-Puren
Zopicalm
Zopicalma
Zopiclon AL
Zopiclon AZU
Zopiclon AbZ
Zopiclon Stada
Zopiclon TAD
Zopiclon beta
Zopiclon-TEVA
Zopiclon-neuraxpharm
Zopiclon-ratiopharm
Zopiclona
Zopiclona [INN-Spanish]
Zopiclone
Zopiclone (JAN/INN)
Zopiclone (TN)
Zopiclone [BAN:INN:JAN]
Zopiclone [Ban:Inn:Jan]
Zopiclone, Imovane, Zimovane, Lunesta
Zopiclonum
Zopiclonum [INN-Latin]
Zopitan
Zorclone
[6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
betapharm brand of zopiclone
ct-Arzneimittel brand of zopiclone
nchembio747-comp16
neuraxpharm brand of zopiclone
ratio-Zopiclone
zopiclodura
zopiclon von ct
zopiclone
24
AcetaminophenapprovedPhase 11026103-90-21983
Synonyms:
4'-Hydroxyacetanilide
4'-hydroxyacetanilide
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
4-acetamidophenol
A-Per
A.F. Anacin
AC1Q1KYJ
AC1Q1KYK
APAP
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-Tap
Acenol
Acephen
Acertol
Aceta Elixir
Aceta Tablets
Acetaco
Acetagesic
Acetalgin
Acetaminofen
Acetaminophen
Acetaminophen Uniserts
Acetamol
Acetavance
Acetofen
Actamin
Actamin Extra
Actamin Super
Actifed Plus
Actimol
Actimol Chewable Tablets
Actimol Children'S Suspension
Actimol Infants' Suspension
Actimol Junior Strength Caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen Max
Anacin
Anacin 3
Anacin-3
Anacin-3 Extra Strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
Anhiba
Anoquan
Anti-Algos
Antidol
Anuphen
Apacet
Apacet Capsules
Apacet Elixir
Apacet Extra Strength Caplets
Apacet Extra Strength Tablets
Apacet Regular Strength Tablets
Apadon
Apamid
Apamide
Apitrelal
Apo-Acetaminophen
Arfen
Arthralgen
Asetam
Asomal
Aspac
Aspirin Free Anacin Maximum Strength Caplets
Aspirin Free Anacin Maximum Strength Gel Caplets
Aspirin Free Anacin Maximum Strength Tablets
Aspirin-Free Anacin
Aspirin-Free Excedrin Caplets
Asplin
Atasol
Atasol Caplets
Atasol Drops
Atasol Forte Caplets
Atasol Forte Tablets
Atasol Oral Solution
Atasol Tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap Hc
Banesin
Bayer Select
Bayer Select Allergy-Sinus
Bayer Select Head Cold
Bayer Select Headache Pain
Bayer Select Maximum Strength Headache Pain Relief Formula
Bayer Select Menstrual Multi-Symptom
Bayer Select Sinus Pain Relief
Ben-u-ron
Benmyo
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
CCRIS 3
CHEBI:46195
Cadafen
Calapol
Calmanticold
Calonal
Calpol
Capital
Capital with Codeine
Captin
Causalon
Cefalex
Cetadol
Children'S Acetaminophen Elixir Drops
Children'S Acetaminophen Oral Solution
Children'S Tylenol Chewable
Claradol Codeine
Clixodyne
Co-Gesic
Cod-Acamol Forte
Codabrol
Codalgin
Codapane
Codicet
Codisal
Codisal Forte
Codoliprane
Codral Pain Relief
Cofamol
Conacetol
Contac Cough & Sore Throat Formula
Contra-Schmerz P
Coricidin
Coricidin D
Coricidin Sinus
Cosutone
Croix Blanche
Cuponol
Curadon
Curpol
Custodial
D oliprane
Dafalgan
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril Extra-Strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
Dhc Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
Dol-Stop
Dolcor
Dolefin
Dolegrippin
Dolene AP-65
Dolene Ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol Forte
Dolorstop
Dolotec
Dolprone
Dorocoff
Dresan
Dristan Cold No Drowsiness
Dristancito
Drixoral Plus
Duaneo
Dularin
Duorol
Duracetamol
Duradyne Dhc
Durapan
Dymadon
Dymadon Co
Dymadon Forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-Plus
Eu-Med
Excedrin
Excedrin Caplets
Excedrin Extra Strength Caplets
Excipain
Exdol
Exdol Strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-Gesic
Febrolin
Femcet
Fendon
Fensum
Fepanil
Fever All
Feverall
Feverall Junior Strength
Feverall Sprinkle Caps Junior Strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon P
Freka-cetamol
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap Children'S Elixir
Genapap Children'S Tablets
Genapap Extra Strength Caplets
Genapap Extra Strength Tablets
Genapap Regular Strength Tablets
Genebs
Genebs Extra Strength Caplets
Genebs Regular Strength Tablets
Genebs X-Tra
Geralgine-P
Gripin Bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hy-Phen
Hycomine Compound
Hydrocet
Ildamol
Inalgex
Infadrops
Infants' Feverall
Influbene N
Injectapap
Intensin
Janupap
Jin Gang
Junior Disprol
KBio1_000660
Kataprin
Kinder Finimal
Korum
Kratofin simplex
L024125
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liqiprine
Liquagesic
Liquigesic Co
Liquiprin
Liquiprin Children'S Elixir
Liquiprin Infants" Drops
Lonarid
Lonarid Mono
Lorcet-Hd
Lortab
Lupocet
Lyteca
Lyteca Syrup
Magnidol
Malex N
Malgis
Malidens
Maxadol
Medigesic Plus
Medinol Paediatric
Medocodene
Melabon Infantil
Mexalen
Midol Maximum Strength
Midol PM Night Time Formula
Midol Regular Strength
Midol Teen Formula
Migraleve Yellow
Minafen
Minoset
Miralgin
Momentum
Mono Praecimed
 
Multin
N-(4-Hydroxyphenyl)acetamide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
N-acetyl-p-aminophenol
NAPA
NCX 701
NEBS
NSC3991
Naldegesic
Napafen
Napap
Naprinol
Nealgyl
Nebs
Neo-Fepramol
NeoCitran
Neodol
Neodolito
Neopap
Neotrend
Neuridon
New Cortal for Children
NilnOcen
Nina
No-Febril
Nobedon
Nodolex
Noral
Norcet
Norco
O-Acetaminophenol
Ofirmev
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/Apap 500
Oxycodone 5/Apap 500
PCM Paracetamol Lichtenstein
Paceco
Pacemo
Pacemol
Pacet
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine Co
Panadiene
Panado-Co
Panado-Co Caplets
Panadol
Panadol Extra Strength
Panadol Junior Strength Caplets
Panadol Maximum Strength Caplets
Panadol Maximum Strength Tablets
Panale ve
Panaleve
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-Deine #3
Papa-Deine #4
Para-Suppo
Para-Tabs
Paracemol
Paracenol
Paracet
Paracetamol
Paracetamol AL
Paracetamol Antipanin P
Paracetamol BC
Paracetamol Basics
Paracetamol DC
Paracetamol Dr. Schmidgall
Paracetamol Fecofar
Paracetamol Genericon
Paracetamol Hanseler
Paracetamol Harkley
Paracetamol Heumann
Paracetamol Hexal
Paracetamol Italfarmaco
Paracetamol Nycomed
Paracetamol PB
Paracetamol Raffo
Paracetamol Ratiopharm
Paracetamol Rosch
Paracetamol Saar
Paracetamol SmithKline Beecham
Paracetamol Stada
Paracetamol Winthrop
Paracetamol von ct
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Paracétamol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
Paramol
Paramolan
Paranox
Parapan
Parasedol
Parasin
Paraspen
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
Pe-Tam
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-Demi
Percogesic with Codeine
Perdolan Mono
Perfalgan
Phenaphen
Phenaphen Caplets
Phenaphen W/Codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin Forte
Pinex
Piramin
Pirinasol
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet World
Redutemp
Reliv
Remedol
Rhinex D-Lay Tablets
Rivalgyl
Robigesic
Robitussin Night Relief
Rockamol Plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
SK-Apap
SPBio_002836
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten Rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sine-Off Sinus Medicine Caplets
Sinedol
Sinmol
Sinubid
Snaplets-FR
Spalt N
Spalt fur die nacht
St Joseph Aspirin-Free
St Joseph Aspirin-Free for Children
St. Joseph Cold Tablets for Children
St. Joseph Fever Reducer
Stanback
Stopain
Sudafed Severe Cold Formula
Sudafed Sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-M
Synalgos-Dc-A
TYL
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol Extra Strength Caplets
Tapanol Extra Strength Tablets
Tapar
Tavist Allergy/Sinus/Headache
Tazamol
Temlo
Tempanal
Tempra
Tempra Caplets
Tempra Chewable Tablets
Tempra D.S
Tempra Drops
Tempra Syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
Tizide
Tocris-1706
Toximer P
Tralgon
Treupel N
Treupel mon
Treuphadol
Triad
Triaminic Sore Throat Formula
Triaprin
Tricoton
Tussapap
Ty lenol
Tycolet
Tylenol
Tylenol (TN)
Tylenol Allergy Sinus
Tylenol Arthritis Extended Relief
Tylenol Caplets
Tylenol Children'S Chewable Tablets
Tylenol Children'S Elixir
Tylenol Children'S Suspension Liquid
Tylenol Drops
Tylenol Elixir
Tylenol Extra Strength Adult Liquid Pain Reliever
Tylenol Extra Strength Caplets
Tylenol Extra Strength Gelcaps
Tylenol Extra Strength Tablets
Tylenol Gelcaps
Tylenol Infants Drops
Tylenol Infants" Suspension Drops
Tylenol Junior Strength Caplets
Tylenol Junior Strength Chewable Tablets
Tylenol Regular Strength Caplets
Tylenol Regular Strength Tablets
Tylenol Tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin Extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor Richet
Vicodin
Vicodin Es
Vicodin Hp
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
acetaminofén
acétaminophène
alpha-Per
p-(Acetylamino)phenol
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
p-acetamidophenol
p-acetaminophenol
p-hydroxy-acetanilid
p-hydroxyacetanilide
p-hydroxyphenolacetamide
25
Alprazolamapproved, illicit, investigationalPhase 16928981-97-72118
Synonyms:
28981-97-7
611026_ALDRICH
611026_FLUKA
8-Chloro-1-methyl-6-(phenyl-d5)-4H-(1,2,4)triazolo[4,3-a][1,4]benzodiazepine
8-Chloro-1-methyl-6-phenyl-4H-S-triazolo(4,3-a)(1,4)benzodiazepine
8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine
8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-alpha)(1,4)benzodiazepine
8-Chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine
A6551_FLUKA
A6551_SIGMA
A8800_SIGMA
AC-18721
AC1L1CYL
AKOS005066050
AP-1002
AZ-002
Alcelam
Algad
Alpaz
Alphapharm Brand of Alprazolam
Alplax
Alpram
Alprax
Alprazolam
Alprazolam (JP15/USP/INN)
Alprazolam Alphapharm Brand
Alprazolam Apotex Brand
Alprazolam Kenral Brand
Alprazolam Novopharm Brand
Alprazolam Nu-Pharm Brand
Alprazolam Orion Brand
Alprazolam Pfizer Brand
Alprazolam Temmler Brand
Alprazolam [USAN:INN:BAN:JAN]
Alprazolam extended release tablets
Alprazolam intensol
Alprazolam solution
Alprazolam-d5
Alprazolamum
Alprazolamum [INN-Latin]
Alprazolan
Alpronax
Alprox
Alviz
Alzam
Alzolam
Alzon
Anpress
Apo Alpraz
Apo-Alpraz
ApoAlpraz
Apotex Brand of Alprazolam
Arzneimittelwerk Dresden Brand of Alprazolam
Azor
BIDD:GT0475
BIDD:PXR0150
BRN 1223125
Bestrol
Bio-0790
C06817
CHEBI:2611
CHEMBL661
CID2118
CPD000149316
Cassadan
Constan
D 65MT
D-65MT
D000525
D00225
D65MT
DB00404
DEA No. 2882
EINECS 249-349-2
Esparon
Frontal
Gen-Alprazolan
HMS2051A10
 
HSDB 7207
Helex
I14-7472
Intensol
Kenral Brand of Alprazolam
Ksalol
LS-156344
MLS000559000
MLS000759485
Mialin
MolPort-002-507-836
NCGC00159466-02
NCGC00159466-03
Neurol
Niravam
Novo Alprazol
Novo-Alprazol
NovoAlprazol
Novopharm Brand of Alprazolam
Nu Alpraz
Nu Pharm Brand of Alprazolam
Nu-Alpraz
Nu-Pharm Brand of Alprazolam
NuAlpraz
Orion Brand of Alprazolam
Panistat
Panix
Pfizer Brand of Alprazolam
Pharnax
Prazam
Prazolan
Prinox
Ralozam
Relaxol
Restyl
SAM001246696
SMR000149316
STK590494
Solanax
Staccato-alprazolam
TGAR01P
TUS-1
Tafil
Tafil D
Temmler Brand of Alprazolam
Tensivan
Tranax
Trankimazin
Tranquinal
Tricalma
Tus 1
U 31889
U-31,889
U-31889
U31,889
UNII-YU55MQ3IZY
Unilan
Valeans
Xanagis
Xanax
Xanax (TN)
Xanax TS
Xanax XR
Xanolam
Xanor
ZINC00000903
Zacetin
Zanapam
Zaxan
Zenax
Zolam
Zolan
Zolarem
Zoldac
Zoldax
Zopax
Zopic
Zotran
alprazolam
nchembio747-comp35
26
Memantineapproved, investigationalPhase 118119982-08-24054
Synonyms:
1,3-Dimethyl-5-adamantanamine
1-Amino-3,5-dimethyladamantane
19982-08-2
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-adamantylamine
3,5-Dimethyl-1-aminoadamantane
3,5-Dimethyladamantan-1-ylamine
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
3,5-dimethyladamantan-1-amine
3,5-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
41100-52-1 (Hydrochloride)
51052-62-1
AB00053600
AC1L1HB7
AKOS000113995
BBL000737
BPBio1_001117
BPBio1_001270
BSPBio_001015
Biomol-NT_000209
C13736
CBMicro_020348
CHEBI:152523
CHEMBL807
CID4054
D08174
DB01043
DMAA
DivK1c_000068
EU-0053634
Ebixa
Exiba
Exiba (TN)
HMS500D10
HSDB 7327
IDI1_000068
KBio1_000068
KBio2_001087
KBio2_003655
 
KBio2_006223
KBio3_001926
KBioGR_001543
KBioSS_001087
LS-157051
Lopac0_000861
Memantin
Memantina
Memantina [INN-Spanish]
Memantine
Memantine (INN)
Memantine HCL
Memantine Hydrochloride
Memantine [INN:BAN]
Memantine [INN]
Memantinum
Memantinum [INN-Latin]
MolPort-002-041-858
NCGC00015705-05
NCGC00024782-02
NCGC00024782-03
NINDS_000068
Namenda
Oprea1_480562
Prestwick0_000978
Prestwick1_000978
Prestwick2_000978
Prestwick3_000978
SPBio_001456
SPBio_002926
ST057652
STK520682
Spectrum2_001408
Spectrum3_000923
Spectrum4_001022
Spectrum5_001355
Spectrum_000607
UNII-W8O17SJF3T
ZERO/006024
memantine
27
TiclopidineapprovedPhase 147155142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
28
PembrolizumabapprovedPhase 15071374853-91-4
Synonyms:
Keytruda
 
MK-3475
lambrolizumab
29
Clopidogrelapproved, nutraceuticalPhase 1778120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
IDI1_000787
 
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
30Antihypertensive AgentsPhase 14207
31Neurotransmitter AgentsPhase 1, Early Phase 118340
32Nootropic AgentsPhase 1716
33Natriuretic AgentsPhase 11697
34Peripheral Nervous System AgentsPhase 1, Early Phase 123689
35Sodium Potassium Chloride Symporter InhibitorsPhase 1181
36Platelet Aggregation InhibitorsPhase 12516
37Psychotropic DrugsPhase 16430
38Purinergic P2 Receptor AntagonistsPhase 1795
39
protease inhibitorsPhase 15471
Synonyms:
 
protease inhibitors
40Tranquilizing AgentsPhase 14265
41Purinergic P2Y Receptor AntagonistsPhase 1793
42Pharmaceutical SolutionsPhase 18192
43Fibrinolytic AgentsPhase 12388
44Antiparkinson AgentsPhase 11574
45AntipyreticsPhase 11605
46Cholinergic AgentsPhase 13992
47Anti-Anxiety AgentsPhase 11885
48Hypnotics and SedativesPhase 12616
49AnalgesicsPhase 111733
50Analgesics, Non-NarcoticPhase 16501

Interventional clinical trials:

(show all 27)
idNameStatusNCT IDPhase
1Responses to Influenza Vaccine in Patients With Mitochondrial Disorders (MELAS)CompletedNCT01831934Phase 4
2Oral Melatonin in Critically Ill High-risk PatientsCompletedNCT00470821Phase 4
3Myo-inositol and Melatonin in Pre-menopausal WomenCompletedNCT01115127Phase 2, Phase 3
4Evaluation of Pigmented Skin Lesions With MelaFind(R) SystemCompletedNCT00434057Phase 3
5Evaluating the Effectiveness of a Dichloroacetate in MELAS SyndromeUnknown statusNCT00068913Phase 2
6L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS SyndromeCompletedNCT01603446Phase 2
7Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like EpisodesCompletedNCT00887562Phase 2
8A Long-Term Extension Study of RP103-MITO-001 (NCT02023866) to Assess RP103 in Children With Inherited Mitochondrial DiseaseCompletedNCT02473445Phase 2
9The KHENERGY StudyRecruitingNCT02909400Phase 2
10EPI-743 for Mitochondrial Respiratory Chain DiseasesActive, not recruitingNCT01370447Phase 2
11MELA Study - Hedonic Study on the Taste of Drugs Crushed in Food: Observational Study Involving 16 Healthy VolunteersCompletedNCT02570581Phase 1
12A Dose-escalating Clinical Trial With KH176CompletedNCT02544217Phase 1
13X4P-001 and Pembrolizumab in Patients With Advanced MelanomaRecruitingNCT02823405Phase 1
14Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male VolunteersNot yet recruitingNCT03056209Phase 1
15Mitochondrial nt3243 A>G Mutation in TaiwanUnknown statusNCT02114554
16Propranolol Treatment of Traumatic Memories (PTTM)Unknown statusNCT01069159
17Nitric Oxide Production in MELAS SyndromeCompletedNCT01339494Early Phase 1
18Ketones & Mitochondrial HeteroplasmyCompletedNCT01252979Early Phase 1
19Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic AcidemiaCompletedNCT00004353
20Does the Aid of MelaFind Affect Clinical Management DecisionsCompletedNCT01387581
21MelaFind Evaluations for Patients With Multiple NeviCompletedNCT01700101
22Survey Study - Sensitivity Comparison Between MelaFind and Physician GroupCompletedNCT01011153
23Natural History Study - Mitochondrial DiseaseRecruitingNCT01532791
24North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)RecruitingNCT01694940
25Tissue Sample Study for Mitochondrial DisordersEnrolling by invitationNCT01803906
26Post-Approval Study of MelaFindTerminatedNCT01700114
27Impact of Obstructive SAS on Metastatic Potential of Cutaneous MelanomaWithdrawnNCT02699918Early Phase 1

Search NIH Clinical Center for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes


Cochrane evidence based reviews: melas syndrome

Genetic Tests for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

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Genetic tests related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:

id Genetic test Affiliating Genes
1 Melas24

Anatomical Context for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

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MalaCards organs/tissues related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:

36
Brain, Heart, Skin, Thyroid, Skeletal muscle, Eye, Cerebellum

Publications for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

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Articles related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:

(show all 27)
idTitleAuthorsYear
1
Early Onset of Diabetes Mellitus Accelerates Cognitive Decline in Japanese Patients with Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes. (27063563)
2016
2
A case of rhabdomyolysis after status epilepticus without stroke-like episodes in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. (26960270)
2016
3
Progress in Diagnosing Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episodes. (26112726)
2015
4
When should MELAS (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes) be the diagnosis? (26517220)
2015
5
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes unveiled by valproate. (24082934)
2013
6
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes: an important cause of stroke in young people. (22328278)
2012
7
Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome presenting as acute meningoencephalitis: a case report. (20036095)
2012
8
Diffusion and perfusion characteristics of MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episode) in thirteen patients. (21228936)
2011
9
An autopsy case of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with intestinal bleeding in chronic renal failure. (21631236)
2011
10
Mutations in mitochondrially encoded complex I enzyme as the second common cause in a cohort of Chinese patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes. (21850008)
2011
11
Treatment options for mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome. (20973690)
2010
12
Depressive episode with catatonic features in a case of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). (19451268)
2009
13
Intestinal pseudo-obstruction in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) associated with phenytoin therapy. (18226864)
2008
14
Cardiac scintigraphic findings of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes: A case report. (19343124)
2008
15
Marked left ventricular hypertrophy in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. (17900719)
2008
16
Acute hearing loss in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). (17966957)
2007
17
A follow-up study in a Taiwanese family with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome. (17660142)
2007
18
Anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) during laparotomy. (17285419)
2007
19
Vascular involvement in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. (15894869)
2005
20
Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation. (15969653)
2005
21
Hypothalamic growth hormone deficiency and supplementary GH therapy in two patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes. (12536371)
2002
22
Spinal anesthesia in MELAS syndrome: a case with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes. (11000676)
2000
23
Ketoacidosis accompanied by epileptic seizures in a patient with diabetes mellitus and mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). (11119021)
2000
24
Anesthetic considerations in patients presenting with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome. (9390617)
1997
25
Alzheimer-type pathology in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). (8870835)
1996
26
Mitochondrial DNA mutations in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). (1899574)
1991
27
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes with acanthocytosis: a clinicopathological study of a unique case. (2427665)
1986

Variations for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

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UniProtKB/Swiss-Prot genetic disease variations for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:

70
id Symbol AA change Variation ID SNP ID
1MT-CO3p.Phe251LeuVAR_002169
2MT-ND1p.Met31ThrVAR_004749rs201212638
3MT-ND4p.Thr109AlaVAR_004759rs199476113
4MT-ND5p.Glu145GlyVAR_035425rs267606894
5MT-ND5p.Asp393AsnVAR_035430rs267606897
6MT-ND6p.Ala74ValVAR_014397rs199476107

Clinvar genetic disease variations for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes:

5 (show all 17)
id Gene Variation Type Significance SNP ID Assembly Location
1NDUFS1NM_ 001199981.1(NDUFS1): c.650T> G (p.Val217Gly)SNVLikely pathogenicrs786205666GRCh37Chr 2, 207009730: 207009730
2MT-TCm.5814T> CSNVPathogenicrs200077222GRCh37Chr MT, 5814: 5814
3MFFNM_ 020194.5(MFF): c.190C> T (p.Gln64Ter)SNVPathogenic/ Likely pathogenicrs397514615GRCh37Chr 2, 228195493: 228195493
4MT-TFm.583G> ASNVPathogenicrs118203885GRCh37Chr MT, 583: 583
5MT-TL1m.3243A> GSNVPathogenicrs199474657GRCh37Chr MT, 3243: 3243
6MT-TL1m.3271T> CSNVPathogenicrs199474658GRCh37Chr MT, 3271: 3271
7MT-TQm.4332G> ASNVPathogenicrs199476141GRCh37Chr MT, 4332: 4332
8MT-ND6m.14453G> ASNVPathogenicrs199476107GRCh37Chr MT, 14453: 14453
9MT-ND5m.12770A> GSNVPathogenicrs267606894GRCh37Chr MT, 12770: 12770
10MT-ND5m.13045A> CSNVPathogenicrs267606895GRCh37Chr MT, 13045: 13045
11MT-ND5m.13084A> TSNVPathogenicrs267606896GRCh37Chr MT, 13084: 13084
12MT-ND5; MT-TL1m.13513G> ASNVPathogenicrs267606897GRCh37Chr MT, 13513: 13513
13MT-ND5m.13042G> ASNVPathogenicrs267606898GRCh37Chr MT, 13042: 13042
14MT-ND4m.11084A> GSNVPathogenicrs199476113GRCh37Chr MT, 11084: 11084
15MT-ND1m.3697G> ASNVPathogenicrs199476122GRCh37Chr MT, 3697: 3697
16MT-ND1m.3946G> ASNVPathogenicrs199476123GRCh37Chr MT, 3946: 3946
17MT-ND1m.3949T> CSNVPathogenicrs199476124GRCh37Chr MT, 3949: 3949

Expression for genes affiliated with Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

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Search GEO for disease gene expression data for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes.

Pathways for genes affiliated with Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

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GO Terms for genes affiliated with Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

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Cellular components related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial respiratory chain complex IVGO:000575110.9MT-CO1, MT-CO2
2mitochondrial membraneGO:003196610.8MT-ND1, MT-ND4, MT-ND6
3mitochondrial respiratory chain complex IGO:000574710.8MT-ND1, MT-ND4, MT-ND5
4mitochondrial inner membraneGO:000574310.2MT-CO1, MT-CO2, MT-CO3, MT-ND1, MT-ND4, MT-ND5
5respiratory chain complex IVGO:00452779.9MT-CO1, MT-CO2, MT-CO3
6respiratory chainGO:00704699.7MT-CO1, MT-CO2, MT-ND1, MT-ND4, MT-ND5, MT-ND6
7mitochondrionGO:00057399.5GTPBP3, LARS2, MT-CO1, MT-CO2, MT-CO3, MT-ND1

Biological processes related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ATP synthesis coupled electron transportGO:004277310.7MT-CO2, MT-ND4, MT-ND5
2mitochondrial electron transport, NADH to ubiquinoneGO:000612010.6MT-ND1, MT-ND4, MT-ND5, MT-ND6
3mitochondrial respiratory chain complex I assemblyGO:003298110.6MT-ND1, MT-ND4, MT-ND5, MT-ND6
4hydrogen ion transmembrane transportGO:190260010.6MT-CO1, MT-CO2, MT-CO3
5mitochondrial electron transport, cytochrome c to oxygenGO:000612310.6MT-CO1, MT-CO2, MT-CO3
6oxidation-reduction processGO:00551149.6MT-CO1, MT-CO2, MT-ND1, MT-ND4, MT-ND5, MT-ND6

Molecular functions related to Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1NADH dehydrogenase (ubiquinone) activityGO:000813710.6MT-ND1, MT-ND4, MT-ND5, MT-ND6
2oxidoreductase activityGO:00164919.6MT-CO1, MT-CO2, MT-ND1, MT-ND4, MT-ND5, MT-ND6

Sources for Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and...

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet