Mitochondrial Myopathy with Diabetes disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Mitochondrial Myopathy with Diabetes

Aliases & Descriptions for Mitochondrial Myopathy with Diabetes:

Name: Mitochondrial Myopathy with Diabetes ⁵⁴ ⁵⁰ ²⁴ ²⁹

Mitochondrial Myopathy, Lipid Type ⁵⁰ ²⁴

Myopathy and Diabetes Mellitus ⁵⁶

Characteristics:

HPO:

³²

mitochondrial myopathy with diabetes:
Onset and clinical course phenotypic variability
Inheritance mitochondrial inheritance

Classifications:

MalaCards categories:
Global: Rare diseases Genetic diseases Metabolic diseases
Anatomical: Neuronal diseases Endocrine diseases

See all MalaCards categories (disease lists)

Orphanet: ⁵⁶

Rare neurological diseases

Inborn errors of metabolism

Rare endocrine diseases

External Ids:

OMIM ⁵⁴ 500002

Orphanet ⁵⁶ ORPHA2596

Sources

Summaries for Mitochondrial Myopathy with Diabetes

MalaCards based summary : Mitochondrial Myopathy with Diabetes, also known as mitochondrial myopathy, lipid type, is related to myopathy and encephalomyopathy, and has symptoms including ataxia, muscular hypotonia and dysarthria. An important gene associated with Mitochondrial Myopathy with Diabetes is MT-TE (Mitochondrially Encoded TRNA Glutamic Acid). The drugs Simvastatin and Menthol have been mentioned in the context of this disorder.

Description from OMIM: 500002

Sources

Related Diseases for Mitochondrial Myopathy with Diabetes

Diseases related to Mitochondrial Myopathy with Diabetes via text searches within MalaCards or GeneCards Suite gene sharing:

id	Related Disease	Score	Top Affiliating Genes
1	myopathy	9.7
2	encephalomyopathy	9.7

Sources

Symptoms & Phenotypes for Mitochondrial Myopathy with Diabetes

Symptoms by clinical synopsis from OMIM:

500002

Clinical features from OMIM:

500002

Human phenotypes related to Mitochondrial Myopathy with Diabetes:

³² (show all 15)

id	Description	HPO Source Accession
1	ataxia ³²	HP:0001251
2	muscular hypotonia ³²	HP:0001252
3	dysarthria ³²	HP:0001260
4	facial palsy ³²	HP:0010628
5	type ii diabetes mellitus ³²	HP:0005978
6	elevated serum creatine phosphokinase ³²	HP:0003236
7	ragged-red muscle fibers ³²	HP:0003200
8	mitochondrial myopathy ³²	HP:0003737
9	hyporeflexia ³²	HP:0001265
10	motor delay ³²	HP:0001270
11	proximal amyotrophy ³²	HP:0007126
12	proximal muscle weakness ³²	HP:0003701
13	emg ³²	HP:0003458
14	decreased activity of mitochondrial complex iv ³²	HP:0008347
15	weakness of orbicularis oculi muscle ³²	HP:0012507

Sources

Drugs & Therapeutics for Mitochondrial Myopathy with Diabetes

Drugs for Mitochondrial Myopathy with Diabetes (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)

id

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Simvastatin

Approved

Phase 3

79902-63-9

54454

Synonyms:

(+)-Simvastatin

(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate

[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate

2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester

2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one

2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one

79902-63-9

AC-1530

AC1L1H1F

AKOS005111006

ARONIS24119

BCBcMAP01_000007

BIDD:GT0769

Bio-0672

BPBio1_001001

BRD-K22134346-001-05-8

BRN 4768037

BSPBio_000909

BSPBio_002337

Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,*aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester

Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester

Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester

butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl]-1-naphthalenyl ester, [1S-[1 alpha,3 alpha,7 beta,8 beta(2S*,4S*),-8a beta

C25H38O5

CCRIS 7558

CHEBI:9150

CHEMBL1064

Cholestat

CID54454

Coledis

Colemin

Corolin

CPD000718785

D00434

D019821

Denan

DivK1c_006991

DRG-0320

Eucor

HMS1570N11

HMS1922H13

HMS2089D12

HMS2093E06

HSDB 7208

InChI=1/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1

KBio1_001935

KBio2_002197

KBio2_004765

KBio2_007333

KBio3_001557

KBioGR_001244

KBioSS_002197

Kolestevan

KS-1113

L 644128-000U

Labistatin

Lipex

Lipinorm

Liponorm

Lipovas

Lodales

LS-46264

Medipo

MK 0733

MK 733

MK-0733

MK733

MK-733

MLS001304029

MLS001333077

MLS001333078

MLS002154038

Modutrol

MolPort-002-507-345

MolPort-002-885-862

NCGC00017324-01

NCGC00017324-02

NCGC00017324-03

nchembio790-comp16

Nivelipol

Nor-Vastina

Pantok

Pepstatin

Prestwick_171

Prestwick0_000865

Prestwick1_000865

Prestwick2_000865

Prestwick3_000865

Rechol

Rendapid

S1792_Selleck

S6196_SIGMA

SAM002589969

Simcor

Simovil

Simvast CR

simvastatin

Simvastatin

Simvastatin & Primycin

Simvastatin (JAN/USP/INN)

Simvastatin [Usan:Ban:Inn]

Simvastatin [USAN:INN:BAN]

Simvastatin lactone

Simvastatin, Compactin

Simvastatina

Simvastatina [Spanish]

Simvastatine

Simvastatine [French]

Simvastatinum

Simvastatinum [Latin]

Simvotin

Sinvacor

Sinvascor

Sivastin

SMR000718785

SPBio_001881

SPBio_002830

SpecPlus_000895

Spectrum_001717

SPECTRUM1504236

Spectrum2_001671

Spectrum3_000669

Spectrum4_000632

Spectrum5_001428

Statin

STK801938

Synvinolin

TNP00259

UNII-AGG2FN16EV

Valemia

Vasotenal

Velostatin

Vytorin

ZINC03780893

Zocor

Zocor (TN)

Zocor, Simlup, Simcard, Simvacor, Simvoget, Zorced, Simvastatin

Zocord

2

Menthol

Approved

Phase 3

2216-51-5

16666

Synonyms:

(&#8722

(-)-(1R,3R,4S)-Menthol

(-)-menthol

()-Menthol

(-)-Menthyl alcohol

(-)-p-Menthan-3-ol

(-)-trans-p-Menthan-cis-ol

(+-)-(1R*,3R*,4S*)-Menthol

(+-)-Menthol

(+)-Neo-menthol

(+)-p-Menthan-3-ol

(+/-)-Menthol

(+/-)-p-Menthan-3-ol

(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol

(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol

(1R)-(-)-Menthol

(1r,2s,5r)-(-)-menthol

(1R,2S,5R)-(-)-menthol

(1R,2S,5R)-Menthol

(1R,3R,4S)-(-)-Menthol

(1R,3R,4S)-(-)-MENTHOL

(1S, 2S, 5R)-(+)-Neomenthol

(1S,2R,5R)-(+)-Isomenthol

(1S,2R,5S)-(+)-Menthol

(1S,2R,5S)-Menthol

(L)-MENTHOL

(r)-(-)-menthol

(R)-(-)-Menthol

)-Menthol

1490-04-6

15356-60-2

15356-70-4

15785_RIEDEL

15785_SIAL

19863P

1-Menthol

20747-49-3

2216-51-5

2-Isopropyl-5-methylcyclohexanol

3-p-Menthol

491-02-1

4-Isopropyl-1-methylcyclohexan-3-ol

551376_ALDRICH

551376_FLUKA

588733_ALDRICH

5-Methyl-2-(1-methylethyl)cyclohexanol

5-Methyl-2-(1-methylethyl)-cyclohexanol

5-methyl-2-(propan-2-yl)cyclohexanol

5-methyl-2-propan-2-ylcyclohexan-1-ol

613290_ALDRICH

613290_FLUKA

63660_FLUKA

63670_ALDRICH

63670_FLUKA

63975-60-0

6C6A4A8C-A054-468C-A1F0-F29E39838CF2

89-78-1

98167-53-4

AC1L1B2E

AC1L28FR

AC1Q1NQ2

AC1Q2QQM

AI3-08161

AI3-52408

AKOS000119740

AR-1J3337

BB_NC-0057

BRN 1902288

BRN 3194263

BSPBio_003062

C00400

C10H20O

Caswell No. 540

CCRIS 3728

CCRIS 375

CCRIS 4666

CCRIS 9231

CHEBI:15409

CHEBI:545611

CHEMBL256087

CHEMBL470670

CID1254

CID16666

cis-1 ,3-trans-1,4-(+-)-menthol

cis-1,3-trans-1,4-(+-)-menthol

D-(-)-Menthol

d,l-Menthol

D00064

D008610

D04849

D04918

DB00825

DivK1c_000820

dl-3-p-Menthanol

dl-Menthol

dl-Menthol (JP15)

d-Menthol

d-Neomenthol

D-p-Menthan-3-ol

EINECS 201-939-0

EINECS 207-724-8

EINECS 216-074-4

EINECS 218-690-9

EINECS 239-387-8

EINECS 239-388-3

EPA Pesticide Chemical Code 051601

FEMA No. 2665

Fisherman's friend lozenges

Fisherman's friend lozenges (TN)

Headache crystals

Hexahydrothymol

HMS1922G13

HMS2092L14

HMS502I22

HSDB 5662

HSDB 593

I06-1216

I14-7371

IDI1_000820

KBio1_000820

KBio2_000785

KBio2_003353

KBio2_005921

KBio3_002562

KBioSS_000785

l-(-)-Menthol

L-(-)-menthol

L-(-)-Menthol

Levomenthol

Levomenthol [INN:BAN]

Levomentholum

Levomentholum [INN-Latin]

Levomentol

l-Menthol

L-menthol

L-Menthol

l-Menthol (JP15)

l-Menthol (natural)

l-Menthol (TN)

LMPR0102090001

LS-2353

LS-57201

LS-886

LS-89531

LS-89533

M0321

M0545

M2772_SIAL

Menthacamphor

Menthol

MENTHOL

--MENTHOL

Menthol (USP)

Menthol (VAN)

Menthol natural

Menthol natural, brazilian

Menthol racemic

Menthol racemique

Menthol racemique [French]

Menthol solution

Menthol, (1alpha,2beta,5alpha)-Isomer

Menthomenthol

Menthyl alcohol

MLS002207256

MolPort-000-849-729

MolPort-001-793-392

NCGC00159382-02

NCGC00159382-03

NCGC00164247-01

NCGC00164247-02

nchembio862-comp1

NCI-C50000

Neoisomenthol

NINDS_000820

NOOLISFMXDJSKH-KXUCPTDWBX

NSC 2603

NSC 62788

NSC2603

NSC62788

Peppermint camphor

p-Menthan-3-ol

Racementhol

Racementhol [INN:BAN]

Racementholum

Racementholum [INN-Latin]

Racementol

Racementol [INN-Spanish]

Racemic menthol

RACEMIC MENTHOL U.S.P.

rac-Menthol

Robitussin Cough Drops

SDCCGMLS-0066659.P001

SMR001306785

SPBio_000869

Spectrum_000305

SPECTRUM1503134

Spectrum2_000855

Spectrum3_001561

Spectrum5_001060

STK802468

Tra-kill tracheal mite killer

U.S.p. Menthol

U.S.P. Menthol

UNII-BZ1R15MTK7

UNII-L7T10EIP3A

UNII-YS08XHA860

W266507_ALDRICH

W266523_ALDRICH

W266590_ALDRICH

WLN: L6TJ AY1&1 BQ D1

WLN: L6TJ AY1&1 DQ D1 -L

ZINC01482164

3

Cholecalciferol

Approved, Nutraceutical

Phase 3

67-97-0

6221 10883523 5280795

Synonyms:

()-Vitamin D3

(+)-vitamin D3

(+)-Vitamin D3

(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol

(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol

(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol

(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol

1406-16-2

25(OH)D

3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol

47763_SUPELCO

57651-82-8

67-97-0

7-Dehydrocholesterol activated

7-Dehydrocholesterol, Activated

7-Dehydrocholesterol, irradiated

7-Dehydrocholestrol, activated

8024-19-9

8050-67-7

89193_FLUKA

9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol

9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol

9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol

9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol

9,10-Secocholesta-5,7,10(19)-trien-3-ol

9,10-Secocholesta-5,7,10-trien-3-ol

AB1002422

AC-11697

AC1L1ECK

AC1L1M23

AC1LU7IZ

AC1NQXLN

AC1NR2UO

AC1NR2UR

AC1NR2UU

AC1NS4AJ

AC1NSHJX

AC1O5EOF

AC1O7GAV

AC1O7GQ3

AC1O8FEU

AC1O8PWJ

AC1OF2GI

AC1OF2GL

AC1OIEW5

AC1OIEWB

ACon1_001997

Activated 7-dehydrocholesterol

Arachitol

Bio-0845

bmse000507

BPBio1_000460

BSPBio_000418

BSPBio_002408

C05443

C1357_SIAL

C27H44O

C9756_SIGMA

C9774_SIAL

Calciol

CAS-67-97-0

CC

CCRIS 5813

CCRIS 6286

CHEBI:283119

CHEBI:28940

CHEMBL1042

CHEMBL432780

cholecalciferol

Cholecalciferol

Cholecalciferol (D3)

Cholecalciferol (JP15/USP)

Cholecalciferol [USAN:BAN:JAN]

Cholecalciferol D3

Cholecalciferol, D3

Cholecalciferolum

CID10000117

CID10045875

CID10340013

CID10883523

CID10894379

CID11014566

CID11025493

CID11058152

CID11463269

CID1548921

CID2735

CID5280795

CID5283710

CID5283711

CID5283712

CID5353527

CID5363362

CID6221

CID6432644

CID6604201

CID6604662

CID6708595

CID6713938

CID6992015

CID6992016

CID7067439

CID7067440

CID7251172

CID7251174

CID9821465

Colecalciferol

Colecalciferol (INN)

Colecalciferolo

Colecalciferolo [DCIT]

colecalciferolum

Colecalciferolum

Colecalciferolum [INN-Latin]

Colecalcipherol

D00188

D3-Vicotrat

D3-Vigantol

DB00169

Delsterol

Delta-D

Delta-D (TN)

Deparal

Devaron

DivK1c_006276

Duphafral D3 1000

Ebivit

EINECS 200-673-2

EINECS 215-797-2

EPA Pesticide Chemical Code 202901

FeraCol

Granuvit D3

HMS1569E20

HMS2092M12

HSDB 820

I05-0041

Irradiated 7-dehydrocholesterol

KBio1_001220

KBio2_001643

KBio2_004211

KBio2_006779

KBio3_001628

KBioGR_001602

KBioSS_001643

LMST03020001

LMST03020219

LMST03020220

LMST03020221

LS-1570

LS-825

LT00244775

MEGxm0_000458

Micro-dee

MolPort-001-740-051

MolPort-001-785-972

MolPort-003-666-021

MolPort-004-946-964

NCGC00016301-01

NCGC00017328-01

NCGC00091072-01

NCGC00142511-01

NCGC00159331-02

NCGC00159331-04

NCGC00178668-01

NCGC00179565-01

NCGC00179565-02

NEO Dohyfral D3

NSC 375571

NSC375571

NSC-375571

Oleovitamin D3

Prestwick_63

Prestwick0_000429

Prestwick1_000429

Prestwick2_000429

Prestwick3_000429

Provitamine

Provitina

Quintox

Rampage

Ricketon

SMP1_000068

SPBio_001298

SPBio_002357

SpecPlus_000180

Spectrum_001163

Spectrum2_001369

Spectrum3_000764

Spectrum4_001201

SR-05000001559

SR-05000001559-3

ST057172

TNP00266

Trivitan

UNII-1C6V77QF41

UPCMLD-DP152

UPCMLD-DP152:001

VidDe-3-hydrosol

Vi-De3

Vi-de-3-hydrosol

Videkhol

Vigantol

Vigorsan

VITAMIN D

vitamin d-3

Vitamin D3

Vitamin D-3

Vitamin D3 emulsifiable

VITAMIN D3 POWDER

VITAMIN_D3

Vitinc Dan-Dee-3

ZINC04474460

ZINC04492874

ZINC04492875

ZINC04492876

ZINC04492878

4

Ergocalciferol

Approved, Nutraceutical

Phase 3

50-14-6

5280793

Synonyms:

(+)-Vitamin D2

(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol

(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol

(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol

(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol

(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol

(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol

(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol

(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol

(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol

(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol

(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol

22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol

31316-19-5

47768_SUPELCO

4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol

50-14-6

7489-18-1

7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87

8017-28-5

9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol

9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol

9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol

9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol

95220_FLUKA

95220_SIGMA

AC-1355

AC1L1FIE

AC1NQXLH

AC1NS4DE

AC1NS9GI

AC1NSSVD

AC1NWAM3

AC1O5EDK

AC1O6WAM

ACon1_002187

Activated ergosterol

beta-Ol

bmse000510

BPBio1_000418

BSPBio_000380

BSPBio_001974

Buco-D

C05441

C28H44O

Calciferol

Calciferol (TN)

Calciferol (vitamin D2)

CALCIFEROL IN A GELATIN MATRIX

CALCIFEROL, U.S.P.

Calciferolum

Calciferon 2

CHEBI:28934

CHEMBL1536

CID11003810

CID3249

CID5280793

CID5315257

CID5353610

CID5356615

CID5702050

CID6432478

CID6536972

component of Geltabs Vitamin D

Condacaps

Condocaps

Condol

Crtron

Crystallina

D00187

Daral

D-Arthin

Davitamon D

Davitin

DB00153

Decaps

Dee-Osterol

Dee-Ron

Dee-Ronal

Dee-Roual

delta-Arthin

Deltalin

delta-Tracetten

De-rat concentrate

Deratol

Detalup

Diactol

Divit urto

Doral

Drisdol

Drisdol (TN)

D-Tracetten

E5750_SIGMA

EINECS 200-014-9

Ercalciol

ergocalciferol

Ergocalciferol

Ergocalciferol (D2)

Ergocalciferol (JP15/USP)

Ergocalciferol [INN:BAN:JAN]

Ergocalciferol oil

Ergocalciferol: Vitamin D

Ergocalciferolo

Ergocalciferolo [DCIT]

Ergocalciferols

Ergocalciferolum

Ergocalciferolum [INN-Latin]

Ergorone

Ergosterol activated

Ergosterol irradiated

'Ergosterol irradiated'

Ergosterol, irradiated

Ertron

Fortodyl

Geltabs

Geltabs Vitamin D

Haliver

Hi-Deratol

HMS1920K20

HMS2091B19

HMS502I07

HSDB 819

Hyperkil

I05-0022

IDI1_000805

Infron

Irradiated ergosta-5,7,22-trien-3.beta.-ol

Irradiated ergosta-5,7,22-trien-3beta-ol

Irradiated ergosta-5,7,22-trien-3-beta-ol

Irradiated ergosterol

LMST03010001

LMST03010014

LS-3228

MEGxm0_000466

Metadee

Mina D2

MLS001332467

MLS001332468

MolPort-001-740-057

MolPort-001-793-930

MolPort-002-526-645

MolPort-003-666-178

MolPort-006-822-629

Mulsiferol

Mykostin

NCGC00142497-01

NCGC00179579-01

NCGC00179579-02

Novovitamin-D

NSC 62792

NSC62792

Oleovitamin D

Oleovitamin D, Synthetic

Oleovitamin D2

Osteil

Ostelin

Prestwick_554

Prestwick3_000420

Radiostol

Radstein

Radsterin

Rodine C

Rodinec

Shock-ferol

Shock-ferol sterogyl

SMR000857106

Sorex C.R

Sorex C.R.

SPECTRUM1500276

Spectrum5_000666

ST057150

Sterogyl

STOCK1N-53397

Synthetic Vitamin D

UNII-VS041H42XC

Uvesterol D

Uvesterol-D

Vigantol

Vio D

Vio-D

Viostdrol

Viosterol

Viosterol in Oil

vitamin d-2

Vitamin D2

Vitamin- D2

VITAMIN D2

VITAMIN D2 WATER DISPERSABLE U.S.P.

Vitamin-?D2

VITAMIN_D2

Vitamina D2

Vitavel-D

WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ

ZINC04474571

ZINC04629876

5

vitamin d

Phase 3

6

Trace Elements

Phase 3

7

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Phase 3

8

Ergocalciferols

Phase 3

9

Vitamins

Phase 3

10

Hypolipidemic Agents

Phase 3,Phase 2

11

Anticholesteremic Agents

Phase 3

12

Lipid Regulating Agents

Phase 3,Phase 2

13

Antimetabolites

Phase 3,Phase 2

14

Micronutrients

Phase 3

15

Bone Density Conservation Agents

Phase 3

16

Vitamin D2

Nutraceutical

Phase 3

17

Calciferol

Nutraceutical

Phase 3

18

Metformin

Approved

Phase 2

657-24-9

14219 4091

Synonyms:

1,1-Dimethyl biguanide

1,1-Dimethylbiguanide

3-(diaminomethylidene)-1,1-dimethylguanidine

657-24-9

AC1L1HE4

AKOS000121065

Apo-Metformin

BIDD:GT0697

BPBio1_000009

BRD-K79602928-003-04-1

BSPBio_000007

BSPBio_002314

C07151

C4H11N5

CAS-1115-70-4

CCRIS 9321

CHEBI:6801

CHEMBL1431

CID4091

cMAP_000016

D04966

DB00331

Diabetosan

Diabex

Dimethylbiguanid

Dimethylbiguanide

Dimethylbiguanidine

Dimethyldiguanide

Dimethylguanylguanidine

DMGG

EINECS 211-517-8

Fluamine

Flumamine

Fortamet

Gen-Metformin

Glifage

Gliguanid

Glucophage

Glucophage XR

Glumetza

Glycon

Haurymelin

Haurymellin

HMS2089D19

HSCI1_000295

Islotin

KBio2_002310

KBio2_004878

KBio2_007446

KBio3_002790

KBioGR_002310

KBioSS_002312

LA-6023

LS-43899

Melbin

metformin

Metformin

Metformin (USAN/INN)

Metformin [USAN:INN:BAN]

Metformin HCL

metformin hydrochloride

Metformina

Metformina [DCIT]

Metformina [Spanish]

Metformine

Metformine [INN-French]

Metformine pamoate

Metforminum

Metforminum [INN-Latin]

Metiguanide

MolPort-002-929-560

MolPort-004-288-389

MolPort-005-767-418

Mylan-Metformin

N,N-Dimethylbiguanide

N,N-Dimethyldiguanide

N,N-dimethylimidodicarbonimidic diamide

N,N-Dimethylimidodicarbonimidic diamide

N1,N1-Dimethylbiguanide

NCGC00016564-01

NCGC00016564-02

NCGC00016564-03

NNDG

Novo-Metformin

Nu-Metformin

PMS-Metformin

Prestwick0_000004

Prestwick1_000004

Prestwick2_000004

Prestwick3_000004

Ran-Metformin

Ratio-Metformin

Riomet

S2483_Selleck

Sandoz Metformin

Siofor

SPBio_001928

STK011633

T5895664

Teva-Metformin

UNII-9100L32L2N

ZINC12859773

19

Bezafibrate

Approved

Phase 2

41859-67-0

39042

Synonyms:

2-(4-{2-[(4-chlorobenzoyl)amino]ethyl}phenoxy)-2-methylpropanoic acid

2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid

2-(P-(2-(P-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid

2-[4-(2-[4-Chlorobenzamido]ethyl)- phenoxy]-2-methylpropanoic acid

2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid

2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid

2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid

41859-67-0

a-[4-(4-chlorobenzoylaminoethyl)phenoxy]isobutyric acid

AB00052265

AB1004588

AC1L20XS

AC1Q5E4V

AC-6817

AKOS005107743

Azufibrat

Azupharma Brand of Bezafibrate

B3346

B7273_SIGMA

Bayer Brand of Bezafibrate

Befibrat

Befizal

Berlin Chemie Brand of Bezafibrate

Berlin-Chemie Brand of Bezafibrate

Betapharm Brand of Bezafibrate

Beza Lande

Beza Puren

Bezabeta

Bezacur

Bezafibrat

Bezafibrat PB

bezafibrate

Bezafibrate (JP15/USAN/INN)

Bezafibrate [USAN:BAN:INN:JAN]

Bezafibrate Azupharma Brand

Bezafibrate Bayer Brand

Bezafibrate Berlin-Chemie Brand

Bezafibrate Betapharm Brand

Bezafibrate Cryopharma Brand

Bezafibrate Elfar Brand

Bezafibrate Hennig Brand

Bezafibrate Hexal Brand

Bezafibrate Isis Brand

Bezafibrate Lakeside Brand

Bezafibrate Merckle Brand

Bezafibrate Roche Brand

Bezafibrate Synthelabo Brand

Bezafibrate TAD Brand

Bezafibrate Teva Brand

Bezafibrato

Bezafibrato [inn-spanish]

Bezafibrato [INN-Spanish]

Bezafibrato [Spanish]

Bezafibratum

Bezafibratum [inn-latin]

Bezafibratum [INN-Latin]

Bezafisal

BezaLande

Beza-Lande

Bezalip

Bezalip Retard

Bezamerck

BezaPuren

Beza-Puren

Bezatol

Bezatol SR

Bezatol sr (tn)

Bezatol SR (TN)

BF-759

Bio2_000034

Bio2_000514

BM 15.075

BM 15075

BM15.075

BM-15.075

BM-15075

Boehringer Mannheim Brand of Bezafibrate

BPBio1_000589

BRD-K46018455-001-06-0

BRN 4267656

BSPBio_000535

BSPBio_001314

BSPBio_003119

C19H20ClNO4

CAS-41859-67-0

CCRIS 9085

Cedur

CHEBI:47612

CHEMBL264374

CID39042

Cryopharma Brand of Bezafibrate

D001629

D01366

DB01393

DB08380

Difaterol

DivK1c_000092

durabezur

EINECS 255-567-9

Elfar Brand of Bezafibrate

Eulitop

Hennig Brand of Bezafibrate

Hexal Brand of Bezafibrate

HMS1361B16

HMS1569K17

HMS1791B16

HMS1921H16

HMS1989B16

HMS2089F04

HMS2092B12

HMS500E14

I06-1311

IDI1_000092

IDI1_033784

Isis Brand of Bezafibrate

KBio1_000092

KBio2_000034

KBio2_001923

KBio2_002602

KBio2_004491

KBio2_005170

KBio2_007059

KBio3_000067

KBio3_000068

KBio3_002619

KBioGR_000034

KBioGR_000669

KBioSS_000034

KBioSS_001923

Lakeside Brand of Bezafibrate

Lipox

LO 44

LS-124535

Merckle Brand of Bezafibrate

MLS000028533

MLS001148205

MolPort-001-738-424

NCGC00016850-01

NCGC00016850-02

NCGC00016850-11

NCGC00023317-03

NCGC00023317-04

NCGC00023317-05

NCGC00023317-06

NCGC00023317-07

NCGC00023317-08

NINDS_000092

PB, Bezafibrat

Prestwick_724

Prestwick0_000378

Prestwick1_000378

Prestwick2_000378

Prestwick3_000378

Reducterol

Regadrin B

Roche Brand of Bezafibrate

Sklerofibrat

SMR000058298

Solibay

SPBio_000824

SPBio_002456

Spectrum_001443

SPECTRUM1502046

Spectrum2_000922

Spectrum3_001500

Spectrum4_000325

Spectrum5_001079

Spectrum5_001967

ST51014927

Synthelabo Brand of Bezafibrate

TAD Brand of Bezafibrate

Teva Brand of Bezafibrate

20

Hypoglycemic Agents

Phase 2

21

Antipsychotic Agents

Phase 2

22

Vitamin E

Approved, Nutraceutical, Vet_approved

59-02-9

14985

Synonyms:

(+)-alpha-Tocopherol

(+)-a-Tocopherol

(+)-α-tocopherol

(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL

(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol

(2R,4'R,8'R)-alpha-Tocopherol

(2R,4'R,8'R)-a-Tocopherol

(2R,4'R,8'R)-α-tocopherol

(R,R,R)-alpha-Tocopherol

(R,R,R)-a-Tocopherol

(R,R,R)-α-tocopherol

5,7,8-trimethyltocol

5,7,8-Trimethyltocol

a-D-Tocopherol

alpha-delta-Tocopherol

alpha-tocopherol

alpha-Tocopherol

Amino-Opti-E

Aquasol E

a-Tocopherol

D-alpha-Tocopherol

Daltose

delta-alpha-Tocopherol

Denamone

d-α-tocopherol

E-200 I.U. Softgels

E-Complex-600

E-Ferol

Eprolin

E-Vitamin succinate

Gordo-Vite E

Phytogermin

Phytogermine

RRR-alpha-tocopherol

RRR-alpha-tocopheryl

Tocopherol

Vitamin E

Vitamin Ea

Vitamin Plus E Softgells

Vitec

23

Tocopherols

24

Tocotrienols

25

Protective Agents

26

Antioxidants

27

Tocopherol

Nutraceutical

28

Tocotrienol

Nutraceutical

Interventional clinical trials:

id	Name	Status	NCT ID	Phase
1	Effect of Vitamin D Supplementation on Exercise Adaptations in Patients on Statin Therapy	Completed	NCT02030041	Phase 3
2	Heart Rate Variability in Response to Metformin Challenge	Completed	NCT02500628	Phase 2
3	A Study of Bezafibrate in Mitochondrial Myopathy	Recruiting	NCT02398201	Phase 2
4	The KHENERGY Study	Recruiting	NCT02909400	Phase 2
5	Mitochondrial nt3243 A>G Mutation in Taiwan	Unknown status	NCT02114554
6	Nutritional Assessment in Mitochondrial Cytopathy	Completed	NCT02375438
7	Fatty Acid Oxidation Disorders & Body Weight Regulation Grant	Completed	NCT00654004
8	Ketones & Mitochondrial Heteroplasmy	Completed	NCT01252979	Early Phase 1
9	Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford	Recruiting	NCT01793168
10	Vitamin E Treatment for Long-Chain 3-Hydroxyacyl Coenzyme A (CoA) Dehydrogenase (LCHAD) Associated Neuropathy	Terminated	NCT00840112

Search NIH Clinical Center for Mitochondrial Myopathy with Diabetes

Sources

Genetic Tests for Mitochondrial Myopathy with Diabetes

Genetic tests related to Mitochondrial Myopathy with Diabetes:

id	Genetic test	Affiliating Genes
1	Mitochondrial Myopathy with Diabetes ²⁹ ²⁴	MT-TE

Sources

Anatomical Context for Mitochondrial Myopathy with Diabetes

Sources

Publications for Mitochondrial Myopathy with Diabetes

Sources

Genes for Mitochondrial Myopathy with Diabetes

Genes related to Mitochondrial Myopathy with Diabetes (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication	PubmedIds
1	MT-TE	Mitochondrially Encoded TRNA Glutamic Acid	468.5	Causative germline mutation ⁵⁶ Genetic Tests ²⁴ GeneCards inferred via : Disorders (show sections)

Sources

Variations for Mitochondrial Myopathy with Diabetes

ClinVar genetic disease variations for Mitochondrial Myopathy with Diabetes:

⁶

id	Gene	Variation	Type	Significance	SNP ID	Assembly	Location
1	MT-TE	m.14709T> C	single nucleotide variant	Pathogenic	rs121434453	GRCh37	Chromosome MT, 14709: 14709

Sources

Expression for Mitochondrial Myopathy with Diabetes

Search GEO for disease gene expression data for Mitochondrial Myopathy with Diabetes.

Sources

Pathways for Mitochondrial Myopathy with Diabetes

Sources

GO Terms for Mitochondrial Myopathy with Diabetes

Sources

Sources for Mitochondrial Myopathy with Diabetes

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ ExPASy

¹⁷ FDA Approved Drugs

¹⁸ FMA

¹⁹ GeneAnalytics

²⁰ GeneCards

²¹ GeneGo (Thomson Reuters)

²² GeneHancer via GeneCards

²³ GeneReviews

²⁴ GeneTests

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MeSH

⁴³ MESH via Orphanet

⁴⁴ MGI

⁴⁵ NCBI Bookshelf

⁴⁶ NCI

⁴⁷ NCIt

⁴⁸ NDF-RT

⁴⁹ NIH Clinical Center

⁵⁰ NIH Rare Diseases

⁵¹ NINDS

⁵² Novoseek

⁵³ Novus Biologicals

⁵⁴ OMIM

⁵⁵ OMIM via Orphanet

⁵⁶ Orphanet

⁵⁷ PathCards

⁵⁸ PharmGKB

⁵⁹ PubMed

⁶⁰ QIAGEN

⁶¹ R&D Systems

⁶² Reactome

⁶³ Sino Biological

⁶⁴ SNOMED-CT

⁶⁵ SNOMED-CT via Orphanet

⁶⁶ UniProtKB/Swiss-Prot

⁶⁷ TGDB

⁶⁸ Tocris

⁶⁹ UMLS

⁷⁰ UMLS via Orphanet

⁷¹ Wikipedia

Mitochondrial Myopathy with Diabetes malady

Aliases & Classifications for Mitochondrial Myopathy with Diabetes

Aliases & Descriptions for Mitochondrial Myopathy with Diabetes:

Characteristics:

HPO:

Classifications:

External Ids:

Summaries for Mitochondrial Myopathy with Diabetes

Related Diseases for Mitochondrial Myopathy with Diabetes

Diseases related to Mitochondrial Myopathy with Diabetes via text searches within MalaCards or GeneCards Suite gene sharing:

Symptoms & Phenotypes for Mitochondrial Myopathy with Diabetes

Symptoms by clinical synopsis from OMIM:

Clinical features from OMIM:

Human phenotypes related to Mitochondrial Myopathy with Diabetes:

Drugs & Therapeutics for Mitochondrial Myopathy with Diabetes

Drugs for Mitochondrial Myopathy with Diabetes (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Genetic Tests for Mitochondrial Myopathy with Diabetes

Genetic tests related to Mitochondrial Myopathy with Diabetes:

Anatomical Context for Mitochondrial Myopathy with Diabetes

Publications for Mitochondrial Myopathy with Diabetes

Genes for Mitochondrial Myopathy with Diabetes

Genes related to Mitochondrial Myopathy with Diabetes (1 elite genes):

Variations for Mitochondrial Myopathy with Diabetes

ClinVar genetic disease variations for Mitochondrial Myopathy with Diabetes:

Expression for Mitochondrial Myopathy with Diabetes

Pathways for Mitochondrial Myopathy with Diabetes

GO Terms for Mitochondrial Myopathy with Diabetes

Sources for Mitochondrial Myopathy with Diabetes