MEPOP
MCID: MTC016
MIFTS: 21

Mitochondrial Neurogastrointestinal Encephalopathy Disease (MEPOP) malady

Gastrointestinal diseases, Neuronal diseases, Muscle diseases, Genetic diseases categories

Summaries for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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21Genetics Home Reference, 42NIH Rare Diseases, 63Wikipedia, 19GeneReviews, 32MalaCards
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NIH Rare Diseases:42 Mitochondrial neurogastrointestinal encephalopathy (mngie) syndrome is a condition that particularly affects the digestive system and nervous system. signs and symptoms of this condition most often begin by age 20 and worsen with time. almost all people with mngie have gastrointestinal dysmotility, in which the muscles and nerves of the digestive system do not move food through the digestive tract efficiently. affected individuals also experience peripheral neuropathy, droopy eyelids (ptosis), weakness of the muscles that control eye movement (ophthalmoplegia), and hearing loss. leukoencephalopathy, which is the deterioration of a type of brain tissue known as white matter, is a hallmark of mngie; however it does not usually cause symptoms in people with this disorder. mutations in the tymp gene cause mngie, and this condition is inherited in an autosomal recessive pattern. last updated: 12/22/2009

MalaCards: Mitochondrial Neurogastrointestinal Encephalopathy Disease, also known as mitochondrial neurogastrointestinal encephalopathy syndrome, is related to familial visceral myopathy with external ophthalmoplegia and paralytic ileus. An important gene associated with Mitochondrial Neurogastrointestinal Encephalopathy Disease is TYMP (thymidine phosphorylase). Affiliated tissues include eye and brain.

Genetics Home Reference:21 Mitochondrial neurogastrointestinal encephalopathy (MNGIE) disease is a condition that affects several parts of the body, particularly the digestive system and nervous system. The major features of MNGIE disease can appear anytime from infancy to adulthood, but signs and symptoms most often begin by age 20. The medical problems associated with this disorder worsen with time.

Wikipedia:63 Mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE), also called... more...

GeneReviews summary for mngie

Aliases & Classifications for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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19GeneReviews, 21Genetics Home Reference, 42NIH Rare Diseases, 20GeneTests, 60UMLS, 44Novoseek
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Classifications:



Aliases & Descriptions:

mitochondrial neurogastrointestinal encephalopathy disease 19 21
mitochondrial neurogastrointestinal encephalopathy syndrome 19 42 20 21 60
myoneurogastrointestinal encephalopathy syndrome 19 42 21
mngie syndrome 19 42 21
oculogastrointestinal muscular dystrophy 42 21
thymidine phosphorylase deficiency 19 21
ogimd 42 21
mngie 42 44
mitochondrial myopathy with sensorimotor polyneuropathy, ophthalmoplegia, and pseudo-obstruction 21
polyneuropathy, ophthalmoplegia, leukoencephalopathy, and intestinal pseudo-obstruction 21
visceral myopathy familial external ophthalmoplegia 60
mngie disease 21
mepop 21
polip 21


Related Diseases for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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17GeneCards, 18GeneDecks
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Diseases related to Mitochondrial Neurogastrointestinal Encephalopathy Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1familial visceral myopathy with external ophthalmoplegia10.5
2paralytic ileus10.1
3mitochondrial dna depletion syndrome, mngie form10.1
4polg-related mitochondrial dna depletion syndrome, mngie form10.1
5liver cirrhosis10.0
6mitochondrial disorders10.0
7trigeminal neuralgia9.9
8hypogonadism9.9
9mitochondrial dna depletion syndrome 8a9.9

Graphical network of diseases related to Mitochondrial Neurogastrointestinal Encephalopathy Disease:



Diseases related to mitochondrial neurogastrointestinal encephalopathy disease

Clinical Features for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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Drugs & Therapeutics for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Genetic Tests for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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20GeneTests
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Genetic tests related to Mitochondrial Neurogastrointestinal Encephalopathy Disease:

id Genetic test Affiliating Genes
1 Mitochondrial Neurogastrointestinal Encephalopathy Disease20 TYMP

Anatomical Context for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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32MalaCards
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MalaCards organs/tissues related to Mitochondrial Neurogastrointestinal Encephalopathy Disease:

32
Eye, Brain

Animal Models for Mitochondrial Neurogastrointestinal Encephalopathy Disease or affiliated genes

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Publications for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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50PubMed
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Articles related to Mitochondrial Neurogastrointestinal Encephalopathy Disease:

idTitleAuthorsYear
1
Diagnosis of mitochondrial neurogastrointestinal encephalopathy disease in gastrointestinal biopsies. (23453626)
2013
2
Mitochondrial Neurogastrointestinal Encephalopathy Disease (20301358)
1993

Genetic Variations for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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Expression for genes affiliated with Mitochondrial Neurogastrointestinal Encephalopathy Disease

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mitochondrial Neurogastrointestinal Encephalopathy Disease

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Pathways for genes affiliated with Mitochondrial Neurogastrointestinal Encephalopathy Disease

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Compounds for genes affiliated with Mitochondrial Neurogastrointestinal Encephalopathy Disease

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GO Terms for genes affiliated with Mitochondrial Neurogastrointestinal Encephalopathy Disease

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Products for genes affiliated with Mitochondrial Neurogastrointestinal Encephalopathy Disease

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  • Antibodies
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Sources for Mitochondrial Neurogastrointestinal Encephalopathy Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet