MCID: MTR027
MIFTS: 18

Mitral Atresia malady

Categories: Rare diseases, Cardiovascular diseases, Fetal diseases

Aliases & Classifications for Mitral Atresia

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Sources:
45NIH Rare Diseases, 51Orphanet, 28ICD10 via Orphanet
See all MalaCards sources

Summaries for Mitral Atresia

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MalaCards based summary: Mitral Atresia is related to prostate cancer and essential tremor. An important gene associated with Mitral Atresia is MCTP2 (Multiple C2 Domains, Transmembrane 2). Affiliated tissues include heart, breast and ovary.

Related Diseases for Mitral Atresia

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Graphical network of the top 20 diseases related to Mitral Atresia:



Diseases related to mitral atresia

Symptoms for Mitral Atresia

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Drugs & Therapeutics for Mitral Atresia

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Drugs for Mitral Atresia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Mechlorethamineapproved30951-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
KBioGR_001448
 
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethamine hydrochloride
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
Valchlor
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
╬▓,╬▓'-dichlorodiethyl-N-methylamine

Interventional clinical trials:

idNameStatusNCT IDPhase
1National Congenital Heart Disease AuditRecruitingNCT02303535
2Adult Pulmonary Valve Replacement: A Simple and Reproducible TechniqueTerminatedNCT00384163

Search NIH Clinical Center for Mitral Atresia

Genetic Tests for Mitral Atresia

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Anatomical Context for Mitral Atresia

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MalaCards organs/tissues related to Mitral Atresia:

33
Heart, Breast, Ovary, Placenta, Tonsil

Animal Models for Mitral Atresia or affiliated genes

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Publications for Mitral Atresia

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Articles related to Mitral Atresia:

(show all 43)
idTitleAuthorsYear
1
Insulin decreases atherosclerosis by inducing endothelin receptor B expression. (27200419)
2016
2
Genetic variations in base excision repair pathway and risk of bladder cancer: a case-control study in the United States. (24038406)
2015
3
Adding another piece to the retinoblastoma puzzle. (26512965)
2015
4
Modulation of LXR-I+ and the effector genes by Ascorbic acid and Statins in psoriatic keratinocytes. (25283515)
2014
5
FASTDEF: fast defocus and astigmatism estimation for high-throughput transmission electron microscopy. (23261401)
2013
6
Sensorineural hearing loss after magnetic resonance imaging. (23844303)
2013
7
Serial changes in high-sensitivity cardiac troponin I in the early diagnosis of acute myocardial infarction. (23910445)
2013
8
CD24 interacts with and promotes the activity of c-src within lipid rafts in breast cancer cells, thereby increasing integrin-dependent adhesion. (21710320)
2012
9
Carbamoylated free amino acids in uremia: HOCl generates volatile protein modifying and cytotoxic oxidant species from N-carbamoyl-threonine but not threonine. (22776434)
2012
10
DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition. (23075851)
2012
11
Non-Hodgkin lymphoma in Chile: a review of 207 consecutive adult cases by a panel of five expert hematopathologists. (22263570)
2012
12
Multiple sialolithiasis in sublingual gland causing dysphagia. (23569485)
2012
13
Surgical management of adult onset age-related distance esotropia. (20795602)
2011
14
Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis. (20556748)
2010
15
Reducing harm associated with anticoagulation: practical considerations of argatroban therapy in heparin-induced thrombocytopenia. (19338378)
2009
16
Interleukin-11 increases invasiveness of JEG-3 choriocarcinoma cells by modulating STAT3 expression. (19716605)
2009
17
Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells. (19758996)
2009
18
Does alpha-methylacyl-CoA-racemase play an important role in perineural tumor invasion? (17640555)
2007
19
No association of interleukin-6 gene polymorphism (-174 G/C) with premature coronary artery disease in a Turkish cohort. (17627181)
2007
20
Inhibition of interferon signaling by rabies virus phosphoprotein P: activation-dependent binding of STAT1 and STAT2. (16501077)
2006
21
Treatment with amino acids in serine deficiency disorders. (16763900)
2006
22
Idiopathic pulmonary hemosiderosis in pregnancy: anesthetic implications. (16171672)
2005
23
Expressions of transforming growth factor-beta1 and collagen IV in renal tissues of patients with chronic allograft nephropathy]. (15897139)
2005
24
Aortic root abscess and secondary infective mitral valve disease: results of surgical endocarditis treatment. (15740952)
2005
25
Biocompatibility of components of a female controlled drug delivery system. (15378489)
2004
26
Mutations in human parainfluenza virus type 3 hemagglutinin-neuraminidase causing increased receptor binding activity and resistance to the transition state sialic acid analog 4-GU-DANA (Zanamivir). (12477836)
2003
27
Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels. (11290752)
2001
28
Anterior uveitis and its relation to stress. (11222351)
2001
29
Chest radiographic features of engraftment syndrome. (10634664)
2000
30
An Ile/Val polymorphism at codon 1464 of the ATP7A gene. (10570920)
1999
31
Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase. (10395804)
1999
32
Hematopoietic growth factors in the treatment of malignant hemopathies]. (9365744)
1997
33
Regulation of p53 expression in HeLa cells. (8829621)
1996
34
Amino acid sequence and carbohydrate structure of a recombinant human tissue factor pathway inhibitor expressed in Chinese hamster ovary cells: one N- and two O-linked carbohydrate chains are located between Kunitz domains 2 and 3 and one N-linked carbohydrate chain is in Kunitz domain 2. (8639592)
1996
35
Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3. (8581420)
1995
36
Degradation of dynorphin-related peptides by the puromycin-sensitive aminopeptidase and aminopeptidase M. (7790884)
1995
37
Sonographic measurement of renal enlargement in children with acute pyelonephritis and time needed for resolution: implications for renal growth assessment. (7618567)
1995
38
Identification of novel phosphorylation sites in murine A-type lamins. (8477740)
1993
39
Bilateral Horner's syndrome secondary to multinodular goiter. (3752761)
1986
40
Cytomegalovirus granulomatous hepatitis. (218449)
1979
41
Neurilemmoma of tonsil. (1184990)
1975
42
Bilirubin binding and kernicterus. (4899063)
1969
43
The value of upright roentgenograms of the maternal pelvis at or near term with particular reference to placenta praevia. (15393511)
1949

Variations for Mitral Atresia

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Expression for genes affiliated with Mitral Atresia

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Search GEO for disease gene expression data for Mitral Atresia.

Pathways for genes affiliated with Mitral Atresia

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GO Terms for genes affiliated with Mitral Atresia

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Sources for Mitral Atresia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet