MCID: MTR027
MIFTS: 16

Mitral Atresia malady

Rare diseases, Cardiovascular diseases, Fetal diseases categories

Aliases & Classifications for Mitral Atresia

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Sources:
45NIH Rare Diseases, 51Orphanet, 28ICD10 via Orphanet
See all sources

Summaries for Mitral Atresia

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MalaCards based summary: Mitral Atresia is related to cor triatriatum and truncus arteriosus. An important gene associated with Mitral Atresia is MCTP2 (Multiple C2 Domains, Transmembrane 2). Affiliated tissues include heart.

Related Diseases for Mitral Atresia

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Diseases related to Mitral Atresia via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1cor triatriatum10.3
2truncus arteriosus10.2
3hypoplastic left heart syndrome 210.1
4pulmonary hypertension10.1
5ventricular septal defect10.1
6aortic coarctation10.1
7congenital mitral stenosis10.1
8transposition of the great arteries10.1
9tricuspid atresia10.1
10interatrial communication10.1

Graphical network of diseases related to Mitral Atresia:



Diseases related to mitral atresia

Symptoms for Mitral Atresia

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Drugs & Therapeutics for Mitral Atresia

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Drugs for Mitral Atresia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Mechlorethamineapproved41051-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
KBioGR_001448
 
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethamine hydrochloride
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
Valchlor
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
╬▓,╬▓'-dichlorodiethyl-N-methylamine

Interventional clinical trials:

idNameStatusNCT IDPhase
1National Congenital Heart Disease AuditRecruitingNCT02303535
2Adult Pulmonary Valve Replacement: A Simple and Reproducible TechniqueTerminatedNCT00384163

Search NIH Clinical Center for Mitral Atresia

Genetic Tests for Mitral Atresia

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Anatomical Context for Mitral Atresia

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MalaCards organs/tissues related to Mitral Atresia:

33
Heart

Animal Models for Mitral Atresia or affiliated genes

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Publications for Mitral Atresia

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Articles related to Mitral Atresia:

(show all 43)
idTitleAuthorsYear
1
Mitral atresia with transposed great arteries and normal semilunar valves: a rare combination. (26394988)
2015
2
Transcatheter left ventricular outflow tract stent placement in a low birth weight child with hypoplastic left ventricle, mitral atresia, transposition of the great arteries, ventricular septal defect and severe pulmonary stenosis. (23832567)
2014
3
Accessory pathway reciprocating tachycardia involving twin AV nodes in a patient with atrioventricular discordance and mitral atresia. (20025717)
2010
4
Prenatal diagnosis of mitral atresia with atrial septal defect of the septum primum: a case report. (18186140)
2008
5
Levoatrial cardinal vein in mitral atresia and closed foramen ovale: prenatal diagnosis and perinatal management. (18634108)
2008
6
Stage I palliation for interrupted "right" aortic arch associated with mitral atresia. (17126163)
2006
7
Double-outlet right ventricle with absent left ventricle and mitral atresia in a fetus with a deletion 22q12. (15386448)
2004
8
Normally connected anomalously draining obstructed pulmonary veins in an infant with mitral atresia: clinical presentation and catheter management. (12360385)
2003
9
Staged Fontan procedure for mitral atresia associated with severe tricuspid regurgitation, pulmonary hypertension, and pulmonary artery distortion. (11993200)
2002
10
Anastomosis between the left atrial appendage and left superior vena cava in a patient with mitral atresia. (12478871)
2002
11
Surgical palliation of truncus arteriosus with mitral atresia and hypoplastic left ventricle. (9456135)
1998
12
Total anomalous pulmonary venous drainage and mitral atresia. (7997432)
1994
13
Levoatriocardinal vein in mitral atresia mimicking obstructive total anomalous pulmonary venous connection. (7868279)
1994
14
Mitral atresia with a large left ventricle and an underdeveloped or absent right ventricular sinus: clinical profile, anatomic data and surgical considerations. (1593052)
1992
15
Cor triatriatum associated with total anomalous pulmonary venous drainage in the setting of mitral atresia and a restrictive interatrial communication. (1614919)
1992
16
Truncus arteriosus associated with mitral atresia and a hypoplastic left ventricle. (1866335)
1991
17
Mitral atresia with double outlet right ventricle in an asymptomatic adult. (2335403)
1990
18
Absence of the aortic valve cusps with mitral atresia, normal left ventricle, and intact ventricular septum. (2328173)
1990
19
Mitral atresia with premature closure of the oval foramen, right-sided levoatriocardinal vein and thrombus formation in the left atrium. (3818138)
1987
20
Mitral atresia. Morphological details. (6696802)
1984
21
The clinical morphology of mitral atresia. Atresia of the left atrioventricular valve. (7049816)
1981
22
Mitral atresia. (502577)
1979
23
Mitral atresia. (502578)
1979
24
Cardiac rhabdomyoma simulating mitral atresia. (830488)
1977
25
Mitral atresia with premature closure of foramen ovale. A rare hemodynamic cause for failure of Blalock-Taussig anastomosis to relieve inadequate pulmonary blood flow. (1249947)
1976
26
Mitral atresia with normal aortic valve: a study of eighteen cases and a review of the literature. (1269115)
1976
27
Overriding right atrioventricular valve in association with mitral atresia. (4808756)
1974
28
Ultrasoundcardiographic studies of the mitral valve region in young infants with mitral atresia, mitral stenosis, hypoplasia of the left ventricle, and cor triatriatum. (5009477)
1972
29
Mitral atresia and occlusive left atrial thrombus. (18610231)
1970
30
Mitral atresia and occlusive left atrial thrombus. A case with 11 years of survival. (5351304)
1969
31
Congenital mitral atresia. (5642422)
1968
32
Congenital mitral atresia with transposition of the great vessels. (5658213)
1968
33
Palliative surgery for mitral atresia. (4167913)
1967
34
Coexistent aortic and mitral atresia associated with persistent common atrioventricular canal. (5837152)
1965
35
MITRAL ATRESIA ASSOCIATED WITH PULMONARY VENOUS ANOMALIES. (14132027)
1964
36
Mitral atresia with levoatriocardinal vein. A form of congenital pulmonary venous obstruction. (14467098)
1962
37
Electrocardiograms of more than routine interest. The electrocardiogram in a patient with mitral atresia and single functional ventricle. (13961575)
1961
38
Surgical management of unusual cardivascular anomalies: complete transposition of the great vessels, vascular rings, congenital mitral stenosis, mitral atresia, cor triatriatum, congenital aortic stenosis and tricuspid atresia. (13740234)
1961
39
Mitral atresia with normal aortic valve. Report of 11 cases and review of the literature. (13843122)
1960
40
Congenital mitral atresia. (13545179)
1958
41
Congenital mitral atresia with hypoplastic nonfunctioning left heart. (14397834)
1955
42
Congenital mitral atresia; report of two cases. (15405867)
1950
43
Congenital mitral atresia, transposition of the great vessels, and congenital aortic coarctation; a case report and an interpretation of the anomaly. (15432291)
1950

Variations for Mitral Atresia

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Expression for genes affiliated with Mitral Atresia

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Search GEO for disease gene expression data for Mitral Atresia.

Pathways for genes affiliated with Mitral Atresia

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GO Terms for genes affiliated with Mitral Atresia

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Sources for Mitral Atresia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet