MCID: MXD014
MIFTS: 27

Mixed Ductal-Endocrine Carcinoma

Categories: Endocrine diseases, Cancer diseases

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

MalaCards integrated aliases for Mixed Ductal-Endocrine Carcinoma:

Name: Mixed Ductal-Endocrine Carcinoma 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:7716
NCIt 47 C6879
SNOMED-CT 64 396892009 999000
UMLS 69 C1301048

Summaries for Mixed Ductal-Endocrine Carcinoma

MalaCards based summary : Mixed Ductal-Endocrine Carcinoma is related to autoimmune enteropathy and malignant ovarian mixed epithelial neoplasm. An important gene associated with Mixed Ductal-Endocrine Carcinoma is CHGA (Chromogranin A), and among its related pathways/superpathways are Adhesion and Cell adhesion_Cell-matrix glycoconjugates. Affiliated tissues include pancreas and liver, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and nervous system

Related Diseases for Mixed Ductal-Endocrine Carcinoma

Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 210)
id Related Disease Score Top Affiliating Genes
1 autoimmune enteropathy 11.0 CHGA GAST
2 malignant ovarian mixed epithelial neoplasm 10.9 CHGA SYP
3 spinal cord ependymoma 10.9 CHGA SYP
4 signet ring cell intrahepatic cholangiocarcinoma 10.9 CHGA SYP
5 ferguson-smith tumor 10.9 ENO2 GAST
6 esophagus adenocarcinoma 10.9 CHGA SYP
7 basophilic carcinoma 10.9 CHGA SYP
8 neurogenic thoracic outlet syndrome 10.9 CHGA SYP
9 supratentorial primitive neuroectodermal tumor 10.9 CHGA ENO2
10 aicardi-goutieres syndrome 10.8 CHGA SYP
11 paranasal sinus cancer 10.8 ENO2 SYP
12 perianal skin paget's disease 10.7 CHGA GAST SYP
13 skin papilloma 10.7 ENO2 SYP
14 brain glioma 10.7 ENO2 SYP
15 gorlin bushkell jensen syndrome 10.7 CHGA ENO2 GAST
16 hair disease 10.7 ENO2 SYP
17 cauda equina intradural extramedullary astrocytoma 10.7 ENO2 SYP
18 ampulla of vater small cell carcinoma 10.7 CHGA ENO2 SYP
19 urethral gland abscess 10.7 CGB3 ENO2
20 nutritional optic neuropathy 10.7 GAST SST
21 rh isoimmunization 10.7 ENO2 SYP
22 childhood choriocarcinoma of the ovary 10.7 CHGA ENO2 SYP
23 osteoblastoma 10.7 CHGA ENO2 SYP
24 small intestine cancer, childhood 10.7 CHGA ENO2 SYP
25 meningitis and encephalitis 10.7 ENO2 MUC1
26 situs inversus 10.7 MUC1 MUC6
27 mast cell neoplasm 10.7 CHGA ENO2 SYP
28 pleomorphic xanthoastrocytoma 10.7 CHGA ENO2 SYP
29 pituitary dwarfism with large sella turcica 10.7 CHGA ENO2 SYP
30 urinary system disease 10.7 MUC1 MUC6
31 breast apocrine carcinoma in situ 10.7 SST SYP
32 nose disease 10.7 CHGA ENO2 SYP
33 pediatric ependymoma 10.7 CHGA ENO2 SYP
34 oral leukoedema 10.7 SST SSTR2
35 diffuse infiltrative lymphocytosis syndrome 10.7 CHGA CHL1 SYP
36 pandas 10.7 GAST SST
37 group b strep disease in newborns 10.7 CHGA ENO2 SYP
38 calcific tendinitis 10.7 CHGA ENO2 SYP
39 middle ear squamous cell carcinoma 10.7 CHGA ENO2 SYP
40 large intestine lipoma 10.7 CHGA ENO2 SYP
41 pyoderma 10.7 CHGA MUC1
42 myoma 10.6 ENO2 MUC1
43 thymus large cell carcinoma 10.6 ENO2 SYP
44 sternum cancer 10.6 CHGA ENO2 SYP
45 perianal hematoma 10.6 GAST SST
46 fallopian tube adenomatoid tumor 10.6 CHGA ENO2
47 bestiality 10.6 MUC1 MUC6
48 eosinophilic gastroenteritis 10.6 CHGA GAST MUC6
49 cauda equina neoplasm 10.6 ENO2 SYP
50 arteriosclerosis obliterans 10.6 ENO2 NCAM1

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to Mixed Ductal-Endocrine Carcinoma

Symptoms & Phenotypes for Mixed Ductal-Endocrine Carcinoma

GenomeRNAi Phenotypes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 9.66 SSTR2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.66 CGB3 CGB7 CGB8
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-160 9.66 CGB7 CGB8 CGB3
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 9.66 CGB7 CGB8 SSTR2 CGB3
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.66 SSTR2
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.66 SSTR2
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-55 9.66 SSTR2
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 9.66 CGB7 CGB8 CGB3
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.66 SSTR2
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-95 9.66 CGB7 CGB8 SSTR2 CGB3

MGI Mouse Phenotypes related to Mixed Ductal-Endocrine Carcinoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.32 NCAM1 SMAD4 SST SSTR2 SYP TERT

Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

Search Clinical Trials , NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

Anatomical Context for Mixed Ductal-Endocrine Carcinoma

MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

39
Pancreas, Liver

Publications for Mixed Ductal-Endocrine Carcinoma

Articles related to Mixed Ductal-Endocrine Carcinoma:

id Title Authors Year
1
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. ( 21311316 )
2011
2
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. ( 22026308 )
2011
3
Mixed ductal-endocrine carcinoma of pancreas. ( 22696627 )
2011
4
A case of mixed ductal-endocrine carcinoma of the pancreas. ( 21424939 )
2011
5
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. ( 18453301 )
2008
6
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. ( 18161862 )
2008
7
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. ( 12685552 )
2002
8
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. ( 10656740 )
2000
9
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. ( 10628803 )
1999

Variations for Mixed Ductal-Endocrine Carcinoma

Expression for Mixed Ductal-Endocrine Carcinoma

Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for Mixed Ductal-Endocrine Carcinoma

Pathways related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.37 CEACAM5 MUC1 NCAM1
2 10.39 CEACAM5 MUC1 NCAM1
3 9.8 GAST MUC6

GO Terms for Mixed Ductal-Endocrine Carcinoma

Cellular components related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.4 CEACAM5 CGB3 CGB7 CGB8 CHGA CHGB

Biological processes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.35 CGB3 CGB7 CGB8 SST SSTR2
2 female gamete generation GO:0007292 8.8 CGB3 CGB7 CGB8

Molecular functions related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 CGB3 CGB7 CHGB GAST SST

Sources for Mixed Ductal-Endocrine Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....