MCID: MXD014
MIFTS: 27

Mixed Ductal-Endocrine Carcinoma malady

Categories: Endocrine diseases, Cancer diseases

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

Aliases & Descriptions for Mixed Ductal-Endocrine Carcinoma:

Name: Mixed Ductal-Endocrine Carcinoma 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:7716
NCIt 47 C6879
SNOMED-CT 64 396892009 999000
UMLS 69 C1301048

Summaries for Mixed Ductal-Endocrine Carcinoma

MalaCards based summary : Mixed Ductal-Endocrine Carcinoma is related to zollinger-ellison syndrome and autoimmune pancreatitis. An important gene associated with Mixed Ductal-Endocrine Carcinoma is CHGA (Chromogranin A), and among its related pathways/superpathways are Adhesion and Cell adhesion_Cell-matrix glycoconjugates. Affiliated tissues include pancreas and liver, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and nervous system

Related Diseases for Mixed Ductal-Endocrine Carcinoma

Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 159)
id Related Disease Score Top Affiliating Genes
1 zollinger-ellison syndrome 30.2 CHGA ENO2 SYP
2 autoimmune pancreatitis 10.4 CHGA GAST
3 peroneal nerve paralysis 10.4 CHGA SYP
4 aggressive digital papillary adenocarcinoma 10.4 ENO2 GAST
5 brain stem ependymoma 10.3 CHGA SYP
6 extrahepatic biliary papillomatosis 10.3 CHGA SYP
7 infiltrating renal pelvis transitional cell carcinoma 10.3 ENO2 SYP
8 sm-ahnmd 10.3 CHGA ENO2
9 gastric duplication cysts 10.3 CHGA GAST SYP
10 acinar cell cystadenocarcinoma 10.3 CHGA GAST SYP
11 thymus small cell carcinoma 10.3 CHGA ENO2 SYP
12 granulocytopenia 10.3 CHGA ENO2 GAST
13 spasmodic dysphonia 10.3 CHGA ENO2 SYP
14 gliofibroma 10.3 CHGA ENO2 SYP
15 barre-lieou syndrome 10.3 CHGA CHL1 SYP
16 piussan lenaerts mathieu syndrome 10.3 CHGA ENO2 SYP
17 pediculus humanus corporis infestation 10.3 CHGA ENO2 SYP
18 epithelioid malignant peripheral nerve sheath tumor 10.3 CHGA SYP
19 growth retardation hydrocephaly lung hypoplasia 10.3 CHGA ENO2 SYP
20 clear cell variant infiltrating bladder urothelial carcinoma 10.3 CHGA ENO2 SYP
21 myelinoclastic diffuse sclerosis 10.3 ENO2 MUC1
22 hepatorenal syndrome 10.3 CHGA SYP TERT
23 secondary syphilis 10.3 CHGA GAST SST
24 brain edema 10.3 CHGA GAST SST
25 cartilage cancer 10.3 CHGA SYP
26 microinvasive cervical squamous cell carcinoma 10.3 CHGA MUC1 SYP
27 colorectal cancer 1 10.3 CHGA ENO2 SYP
28 uterine corpus sarcoma 10.3 ENO2 NCAM1
29 volkmann contracture 10.3 CHGA GAST SST
30 gmppa-cdg 10.3 CHGA CHGB SST
31 bone marrow cancer 10.3 CHGA MUC1 SYP
32 progressive relapsing multiple sclerosis 10.2 CHGA GAST SST
33 adult botryoid rhabdomyosarcoma 10.2 CHGA SST SYP
34 acute pyelonephritis 10.2 CHGA GAST SST
35 maturity-onset diabetes of the young, type 13 10.2 CHGA GAST SST
36 non specific chronic endometritis 10.2 CHGA NCAM1 SYP
37 keloids 10.2 CHGA GAST SST
38 skeletal-extraskeletal angiomatosis 10.2 ENO2 MUC1 SYP
39 cowden syndrome 3 10.2 CHGA SST SYP
40 autosomal recessive stickler syndrome 10.2 ENO2 MUC1 SYP
41 ascariasis 10.2 SST SSTR2
42 gestational ovarian choriocarcinoma 10.2 MUC1 MUC6
43 bone dysplasia azouz type 10.2 CHGA SST SYP
44 gallbladder signet ring cell adenocarcinoma 10.2 CHGA MUC1 MUC6
45 spinal stenosis 10.2 CHGA ENO2 SST
46 pemphigus foliaceus 10.2 ENO2 SST SYP
47 postgastrectomy syndrome 10.2 SST SYP
48 congenital muscular dystrophy with hyperlaxity 10.2 ENO2 MUC1 SYP
49 intrahepatic bile duct adenoma 10.2 NCAM1 SYP
50 villous adenocarcinoma 10.2 CHGA SYP

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to Mixed Ductal-Endocrine Carcinoma

Symptoms & Phenotypes for Mixed Ductal-Endocrine Carcinoma

GenomeRNAi Phenotypes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 9.66 SSTR2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.66 CGB3 CGB7 CGB8
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-160 9.66 CGB3 CGB7 CGB8
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 9.66 CGB3 CGB7 CGB8 SSTR2
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.66 SSTR2
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.66 SSTR2
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-55 9.66 SSTR2
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 9.66 CGB3 CGB7 CGB8
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.66 SSTR2
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-95 9.66 CGB3 CGB7 CGB8 SSTR2

MGI Mouse Phenotypes related to Mixed Ductal-Endocrine Carcinoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.32 CALB2 CHGB CHL1 ENO2 NCAM1 SMAD4

Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

Search Clinical Trials , NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

Anatomical Context for Mixed Ductal-Endocrine Carcinoma

MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

39
Pancreas, Liver

Publications for Mixed Ductal-Endocrine Carcinoma

Articles related to Mixed Ductal-Endocrine Carcinoma:

id Title Authors Year
1
A case of mixed ductal-endocrine carcinoma of the pancreas. ( 21424939 )
2011
2
Mixed ductal-endocrine carcinoma of pancreas. ( 22696627 )
2011
3
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. ( 21311316 )
2011
4
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. ( 22026308 )
2011
5
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. ( 18161862 )
2008
6
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. ( 18453301 )
2008
7
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. ( 12685552 )
2002
8
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. ( 10656740 )
2000
9
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. ( 10628803 )
1999

Variations for Mixed Ductal-Endocrine Carcinoma

Expression for Mixed Ductal-Endocrine Carcinoma

Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for Mixed Ductal-Endocrine Carcinoma

Pathways related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.37 CEACAM5 MUC1 NCAM1
2 10.39 CEACAM5 MUC1 NCAM1
3 9.8 GAST MUC6

GO Terms for Mixed Ductal-Endocrine Carcinoma

Cellular components related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.4 CEACAM5 CGB3 CGB7 CGB8 CHGA CHGB

Biological processes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.35 CGB3 CGB7 CGB8 SST SSTR2
2 female gamete generation GO:0007292 8.8 CGB3 CGB7 CGB8

Molecular functions related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 CGB3 CGB7 CHGB GAST SST

Sources for Mixed Ductal-Endocrine Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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