MCID: MXD014
MIFTS: 28

Mixed Ductal-Endocrine Carcinoma malady

Cancer diseases category

Summaries for Mixed Ductal-Endocrine Carcinoma

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32MalaCards
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MalaCards: Mixed Ductal-Endocrine Carcinoma is related to papillary carcinoma and ductal carcinoma in situ. An important gene associated with Mixed Ductal-Endocrine Carcinoma is SYP (synaptophysin), and among its related pathways is Selected targets of Oct-3/4. The compounds clomiphene citrate and glutaraldehyde have been mentioned in the context of this disorder. Affiliated tissues include pancreas and liver.

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

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Sources:
8Disease Ontology, 60UMLS, 39NCIt, 56SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

mixed ductal-endocrine carcinoma 8 60


External Ids:

Disease Ontology8 DOID:7716
SNOMED-CT56 999000, 396892009
NCIt39 C6879

Related Diseases for Mixed Ductal-Endocrine Carcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1papillary carcinoma30.5KRT19, SYP
2ductal carcinoma in situ10.2
3pancreatic endocrine carcinoma10.2
4pancreatic ductal carcinoma10.2
5gastrinoma10.2
6bile duct carcinoma in situ10.2
7zollinger-ellison syndrome10.2
8bile duct carcinoma10.2
9in situ carcinoma10.2
10pancreatitis10.2
11sertoli cell tumor10.0SYP
12medulloepithelioma10.0SYP
13leydig cell tumor10.0CGB5
14extragonadal germ cell tumor10.0CGB5
15thymus cancer10.0SYP
16ganglioneuroma10.0SYP
17dysgerminoma10.0CGB5
18gynecomastia10.0CGB5
19germinoma10.0CGB5, CGB
20placental site trophoblastic tumor10.0CGB5, CGB
21large cell carcinoma10.0SYP, CGB5
22gestational trophoblastic tumor10.0CGB5, CGB
23endodermal sinus tumor10.0CGB5, CGB
24hyperthyroidism10.0CGB, CGB5
25prostate cancer10.0TERT, CGB
26pituitary adenoma10.0SYP, CGB7
27deficiency anemia10.0CGB5, CGB
28hyperprolactinemia10.0CGB5, CGB
29neuroendocrine carcinoma10.0SYP, KRT19
30oxyphilic adenoma10.0KRT19, SYP
31ectopic pregnancy10.0CGB, CGB7, CGB5
32pregnancy loss10.0CGB5, CGB7, CGB
33gestational trophoblastic neoplasm10.0CGB7, CGB5, CGB
34neural tube defects10.0CGB5, CGB7, CGB
35embryonal cancer10.0CGB7, CGB5, CGB
36adenoameloblastoma10.0TERT, KRT19
37down syndrome10.0CGB7, CGB, CGB5
38seminoma10.0CGB, CGB5, CGB7
39factor v leiden thrombophilia10.0CGB, CGB7, CGB5
40pre-eclampsia10.0CGB, CGB7, CGB5
41sarcoma10.0CGB5, TERT, CGB
42lung cancer10.0KRT19, SYP
43cryptococcosis10.0CGB7, CGB, CGB8, CGB5
44choriocarcinoma10.0CGB, CGB7, CGB5
45pancreatic cancer10.0TERT, KRT19, SYP
46non-small cell lung carcinoma10.0KRT19, TERT, SYP
47lung benign neoplasm10.0KRT19, SYP, TERT
48neuroendocrine tumor10.0KRT19, SYP
49bladder carcinoma10.0TERT, CGB, KRT19
50brain cancer10.0CGB, TERT, CGB5, SYP

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to mixed ductal-endocrine carcinoma

Clinical Features for Mixed Ductal-Endocrine Carcinoma

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Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Mixed Ductal-Endocrine Carcinoma

Drug clinical trials:

Search ClinicalTrials for Mixed Ductal-Endocrine Carcinoma

Search NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Search CenterWatch for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

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Anatomical Context for Mixed Ductal-Endocrine Carcinoma

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32MalaCards
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MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

32
Pancreas, Liver

Animal Models for Mixed Ductal-Endocrine Carcinoma or affiliated genes

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Publications for Mixed Ductal-Endocrine Carcinoma

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Sources:
50PubMed
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Articles related to Mixed Ductal-Endocrine Carcinoma:

idTitleAuthorsYear
1
Mixed ductal-endocrine carcinoma of pancreas. (22696627)
2011
2
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. (22026308)
2011
3
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. (21311316)
2011
4
A case of mixed ductal-endocrine carcinoma of the pancreas. (21424939)
2011
5
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. (18161862)
2008
6
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. (18453301)
2008
7
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. (12685552)
2002
8
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. (10656740)
2000
9
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. (10628803)
1999

Genetic Variations for Mixed Ductal-Endocrine Carcinoma

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Expression for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mixed Ductal-Endocrine Carcinoma

Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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12EMD Millipore
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Pathways related to Mixed Ductal-Endocrine Carcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4CGB, CGB7

Compounds for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Sources:
44Novoseek, 11DrugBank, 49PharmGKB, 28IUPHAR, 59Tocris Bioscience, 2BitterDB, 24HMDB
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Compounds related to Mixed Ductal-Endocrine Carcinoma according to GeneCards/GeneDecks:

(show all 28)
idCompoundScoreTop Affiliating Genes
1clomiphene citrate449.8CGB5, CGB
2glutaraldehyde449.8SYP, CGB5
3ifosfamide44 1110.7CGB, CGB5
4smcc449.6KRT19, SYP
5leucovorin44 49 1111.5CGB, CGB5
6b 723449.5SYP, KRT19
7oestriol449.3CGB5, CGB7, CGB
8hematoxylin449.3KRT19, SYP
9ctp449.3CGB, CGB7, CGB5
10bleomycin44 1110.2CGB5, CGB7, CGB
11methotrexate44 49 1111.2CGB5, CGB7, CGB
12gnrh449.2CGB, CGB7, CGB5
1317beta-hydroxysteroid449.0KRT19, CGB5
14ribonucleic acid448.9TERT, KRT19, CGB5
15paclitaxel44 49 1110.9TERT, KRT19, CGB5
16genistein44 28 59 2 11 2413.8CGB5, SYP, TERT
17glycogen44 249.8CGB5, SYP, KRT19
18cysteine448.8CGB7, CGB, SYP, TERT
19creatinine448.6KRT19, SYP, CGB, CGB5
20paraffin448.6TERT, KRT19, SYP, CGB5
21etoposide44 49 59 1111.5CGB5, CGB7, CGB, SYP, TERT
22lactate448.4CGB5, CGB7, CGB, KRT19
23vegf448.2CGB5, CGB, SYP, KRT19, TERT
24estradiol44 11 2410.1CGB5, CGB7, CGB, SYP, KRT19
25progesterone44 59 28 11 2412.1CGB5, CGB7, CGB, SYP, KRT19
26retinoic acid44 249.0CGB5, CGB7, SYP, KRT19, TERT
27cisplatin44 49 59 1110.7TERT, KRT19, SYP, CGB, CGB7, CGB5
28testosterone44 59 11 2410.6CGB5, CGB7, CGB, SYP, KRT19, TERT

GO Terms for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Products for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mixed Ductal-Endocrine Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet