MCID: MXD014
MIFTS: 26

Mixed Ductal-Endocrine Carcinoma malady

Categories: Endocrine diseases, Cancer diseases

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

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Aliases & Descriptions for Mixed Ductal-Endocrine Carcinoma:

Name: Mixed Ductal-Endocrine Carcinoma 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:7716
SNOMED-CT62 396892009, 999000
NCIt45 C6879

Summaries for Mixed Ductal-Endocrine Carcinoma

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MalaCards based summary: Mixed Ductal-Endocrine Carcinoma is related to gastrinoma and itch e3 ubiquitin ligase deficiency. An important gene associated with Mixed Ductal-Endocrine Carcinoma is CHGA (Chromogranin A), and among its related pathways are Adhesion and Cell adhesion_Cell-matrix glycoconjugates. Affiliated tissues include pancreas and liver, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and nervous system.

Related Diseases for Mixed Ductal-Endocrine Carcinoma

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Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 189)
idRelated DiseaseScoreTop Affiliating Genes
1gastrinoma30.6CHGA, SST
2itch e3 ubiquitin ligase deficiency10.8CHGA, GAST
3ovary mixed epithelial carcinoma10.8CHGA, SYP
4lice infestation10.8CHGA, SYP
5childhood malignant schwannoma10.7CHGA, SYP
6microglandular adenosis of breast10.7CHGA, SYP
7osteoblastoma10.7CHGA, SYP
8urethra adenocarcinoma10.7CHGA, SYP
9esophagus adenocarcinoma10.7CHGA, SYP
10fraxf syndrome10.7CHGA, SYP
11cutaneous mastocytosis10.7CHGA, SYP
12phencyclidine abuse10.7CHL1, SYP
13anaplastic oligoastrocytoma10.7MUC1, SYP
14deep corneal vascularisation10.6GAST, SST
15rectum signet ring adenocarcinoma10.6CHGA, GAST, SYP
16epidermal nevus vitamin d resistant rickets10.6GAST, SYP
17retinal melanoma10.6SST, SYP
18pelvic varices10.6GAST, SST
19lung large cell carcinoma10.6SST, SSTR2
20pseudoglandular variant testicular seminoma10.6CHGA, MUC1
21pancreatic endocrine carcinoma10.6MUC1, MUC6
22isolated levocardia10.6GAST, SST
23anal colloid adenocarcinoma10.6CHGA, SSTR2, SYP
24congenital structural myopathy10.6CHGA, MUC1
25morbid obesity10.6MUC1, MUC6
26froelich syndrome10.6CHGA, CHL1, SYP
27scotoma10.6MUC1, MUC6
28adrenal medulla cancer10.5SST, SSTR2
29mucinous adenocarcinoma10.5CHGA, SMAD4, SYP
30spinal chordoma10.5CHGA, GAST, SST
31extragonadal germ cell cancer10.5CHGA, GAST, SST
32gastrointestinal neuroendocrine benign tumor10.5NCAM1, SYP
33clear cell adenoma10.5CHGA, MUC1, SYP
34lumbar plexus neoplasm10.5CHGA, MUC1, SYP
35diabetes mellitus, transient neonatal, 310.5CHGA, GAST, SST
36hypogonadism cardiomyopathy10.5NCAM1, SYP
37primary progressive multiple sclerosis10.5CHGA, GAST, SST
38gastrointestinal anthrax10.5CHGA, GAST, SST
39focal facial dermal dysplasia10.5CHGA, SST, SYP
40spinal muscular atrophy10.5CHGA, SST
41poliomyelitis10.5CHGA, MUC1, SYP
42pituitary deficiency due to rathke's pouch cysts10.5MUC1, SST
43apocrine adenocarcinoma10.5CHGA, MUC1, MUC6
44intracortical osteogenic sarcoma10.5CHGA, GAST, SST
45pineoblastoma10.5MUC1, SYP
46appendix lymphoma10.5MUC1, MUC6
47pancreatic agenesis10.5CHGA, NCAM1, SYP
48eosinophilic gastritis10.5CHGA, GAST, SST
49immunodeficiency, common variable, 510.5CHGA, GAST, SST
50caroli disease10.5CHGA, NCAM1, SYP

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to mixed ductal-endocrine carcinoma

Symptoms & Phenotypes for Mixed Ductal-Endocrine Carcinoma

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GenomeRNAi Phenotypes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-589.6CGB3, CGB7, CGB8, SSTR2

MGI Mouse Phenotypes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.0CALB2, CHGB, CHL1, ENO2, NCAM1, SMAD4

Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

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Anatomical Context for Mixed Ductal-Endocrine Carcinoma

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MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

36
Pancreas, Liver

Publications for Mixed Ductal-Endocrine Carcinoma

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Articles related to Mixed Ductal-Endocrine Carcinoma:

idTitleAuthorsYear
1
Mixed ductal-endocrine carcinoma of pancreas. (22696627)
2011
2
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. (22026308)
2011
3
A case of mixed ductal-endocrine carcinoma of the pancreas. (21424939)
2011
4
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. (21311316)
2011
5
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. (18161862)
2008
6
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. (18453301)
2008
7
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. (12685552)
2002
8
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. (10656740)
2000
9
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. (10628803)
1999

Variations for Mixed Ductal-Endocrine Carcinoma

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Expression for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Pathways related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.2CEACAM5, MUC1, NCAM1
29.2CEACAM5, MUC1, NCAM1

GO Terms for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Cellular components related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.9CGB3, CGB7, CGB8, CHGB, GAST, MUC6

Molecular functions related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051798.7CGB3, CGB7, CHGB, GAST, SST

Sources for Mixed Ductal-Endocrine Carcinoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet