MCID: MXD014
MIFTS: 27

Mixed Ductal-Endocrine Carcinoma malady

Categories: Endocrine diseases, Cancer diseases

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

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Aliases & Descriptions for Mixed Ductal-Endocrine Carcinoma:

Name: Mixed Ductal-Endocrine Carcinoma 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:7716
SNOMED-CT62 396892009, 999000
NCIt45 C6879

Summaries for Mixed Ductal-Endocrine Carcinoma

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MalaCards based summary: Mixed Ductal-Endocrine Carcinoma is related to zollinger-ellison syndrome and autoimmune pancreatitis. An important gene associated with Mixed Ductal-Endocrine Carcinoma is CHGA (Chromogranin A), and among its related pathways are Gastric acid production and Adhesion. Affiliated tissues include pancreas and liver, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and nervous system.

Related Diseases for Mixed Ductal-Endocrine Carcinoma

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Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 159)
idRelated DiseaseScoreTop Affiliating Genes
1zollinger-ellison syndrome30.2CHGA, ENO2, SYP
2autoimmune pancreatitis10.4CHGA, GAST
3peroneal nerve paralysis10.4CHGA, SYP
4aggressive digital papillary adenocarcinoma10.4ENO2, GAST
5brain stem ependymoma10.3CHGA, SYP
6extrahepatic biliary papillomatosis10.3CHGA, SYP
7infiltrating renal pelvis transitional cell carcinoma10.3ENO2, SYP
8sm-ahnmd10.3CHGA, ENO2
9gastric duplication cysts10.3CHGA, GAST, SYP
10acinar cell cystadenocarcinoma10.3CHGA, GAST, SYP
11thymus small cell carcinoma10.3CHGA, ENO2, SYP
12granulocytopenia10.3CHGA, ENO2, GAST
13spasmodic dysphonia10.3CHGA, ENO2, SYP
14gliofibroma10.3CHGA, ENO2, SYP
15barre-lieou syndrome10.3CHGA, CHL1, SYP
16piussan lenaerts mathieu syndrome10.3CHGA, ENO2, SYP
17pediculus humanus corporis infestation10.3CHGA, ENO2, SYP
18epithelioid malignant peripheral nerve sheath tumor10.3CHGA, SYP
19growth retardation hydrocephaly lung hypoplasia10.3CHGA, ENO2, SYP
20clear cell variant infiltrating bladder urothelial carcinoma10.3CHGA, ENO2, SYP
21myelinoclastic diffuse sclerosis10.3ENO2, MUC1
22hepatorenal syndrome10.3CHGA, SYP, TERT
23secondary syphilis10.3CHGA, GAST, SST
24brain edema10.3CHGA, GAST, SST
25cartilage cancer10.3CHGA, SYP
26microinvasive cervical squamous cell carcinoma10.3CHGA, MUC1, SYP
27colorectal cancer 110.3CHGA, ENO2, SYP
28uterine corpus sarcoma10.3ENO2, NCAM1
29volkmann contracture10.3CHGA, GAST, SST
30gmppa-cdg10.3CHGA, CHGB, SST
31bone marrow cancer10.3CHGA, MUC1, SYP
32progressive relapsing multiple sclerosis10.2CHGA, GAST, SST
33adult botryoid rhabdomyosarcoma10.2CHGA, SST, SYP
34acute pyelonephritis10.2CHGA, GAST, SST
35maturity-onset diabetes of the young, type 1310.2CHGA, GAST, SST
36non specific chronic endometritis10.2CHGA, NCAM1, SYP
37keloids10.2CHGA, GAST, SST
38skeletal-extraskeletal angiomatosis10.2ENO2, MUC1, SYP
39cowden syndrome 310.2CHGA, SST, SYP
40autosomal recessive stickler syndrome10.2ENO2, MUC1, SYP
41ascariasis10.2SST, SSTR2
42gestational ovarian choriocarcinoma10.2MUC1, MUC6
43bone dysplasia azouz type10.2CHGA, SST, SYP
44gallbladder signet ring cell adenocarcinoma10.2CHGA, MUC1, MUC6
45spinal stenosis10.2CHGA, ENO2, SST
46pemphigus foliaceus10.2ENO2, SST, SYP
47postgastrectomy syndrome10.2SST, SYP
48congenital muscular dystrophy with hyperlaxity10.2ENO2, MUC1, SYP
49intrahepatic bile duct adenoma10.2NCAM1, SYP
50villous adenocarcinoma10.2CHGA, SYP

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to mixed ductal-endocrine carcinoma

Symptoms & Phenotypes for Mixed Ductal-Endocrine Carcinoma

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GenomeRNAi Phenotypes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-849.4CGB3, CGB7, CGB8, SSTR2

MGI Mouse Phenotypes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.5CALB2, CHGB, CHL1, ENO2, NCAM1, SMAD4

Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

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Anatomical Context for Mixed Ductal-Endocrine Carcinoma

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MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

36
Pancreas, Liver

Publications for Mixed Ductal-Endocrine Carcinoma

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Articles related to Mixed Ductal-Endocrine Carcinoma:

idTitleAuthorsYear
1
A case of mixed ductal-endocrine carcinoma of the pancreas. (21424939)
2011
2
Mixed ductal-endocrine carcinoma of pancreas. (22696627)
2011
3
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. (21311316)
2011
4
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. (22026308)
2011
5
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. (18161862)
2008
6
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. (18453301)
2008
7
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. (12685552)
2002
8
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. (10656740)
2000
9
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. (10628803)
1999

Variations for Mixed Ductal-Endocrine Carcinoma

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Expression for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Pathways related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8GAST, MUC6
29.0CEACAM5, MUC1, NCAM1
39.0CEACAM5, MUC1, NCAM1

GO Terms for genes affiliated with Mixed Ductal-Endocrine Carcinoma

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Cellular components related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055765.7CEACAM5, CGB3, CGB7, CGB8, CHGA, CHGB

Biological processes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1female gamete generationGO:00072928.9CGB3, CGB7, CGB8
2cell-cell signalingGO:00072678.6CGB3, CGB7, CGB8, SST, SSTR2

Molecular functions related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051798.5CGB3, CGB7, CHGB, GAST, SST

Sources for Mixed Ductal-Endocrine Carcinoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet