MCID: MXD010
MIFTS: 29

Mixed Epithelial Stromal Tumour malady

Summaries for Mixed Epithelial Stromal Tumour

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63Wikipedia, 32MalaCards
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Wikipedia:63 A cystic nephroma, also known as multilocular cystic nephroma, mixed epithelial stromal tumour (MEST)... more...

MalaCards: Mixed Epithelial Stromal Tumour is related to cystic nephroma and hemangioblastoma. An important gene associated with Mixed Epithelial Stromal Tumour is INHA (inhibin, alpha), and among its related pathways is Ovarian Infertility Genes. The compounds fatty acid and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include kidney, and related mouse phenotypes are homeostasis/metabolism and normal.

Aliases & Classifications for Mixed Epithelial Stromal Tumour

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8Disease Ontology, 60UMLS, 39NCIt
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Aliases & Descriptions:

mixed epithelial stromal tumour 8


External Ids:

Disease Ontology8 DOID:5088
NCIt39 C37265

Related Diseases for Mixed Epithelial Stromal Tumour

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17GeneCards, 18GeneDecks
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Diseases related to Mixed Epithelial Stromal Tumour via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 71)
idRelated DiseaseScoreTop Affiliating Genes
1cystic nephroma10.2
2hemangioblastoma10.0INHA
3angiosarcoma10.0CALB2
4thymoma10.0CALB2
5germinoma10.0INHA
6adenomatoid tumor10.0CALB2
7desmoid tumor10.0DES
8congestive heart failure10.0MME
9colon cancer10.0CALB2
10leiomyomatosis10.0PGR
11lipoma10.0DES
12adenofibroma10.0INHA, CALB2
13hypertension10.0MME
14adenoma10.0CALB2, INHA
15ductal carcinoma in situ10.0PGR
16pheochromocytoma10.0INHA, CALB2
17sex cord-gonadal stromal tumor10.0CALB2, INHA
18seminoma10.0INHA, CALB2
19sarcoma10.0DES, CALB2
20chordoma10.0INHA, DES
21cryptorchidism10.0CYP19A1
22cystadenoma10.0MME, INHA
23aorta atresia10.0CYP19A1, INHA
24liposarcoma10.0CALB2, DES
25malignant mesothelioma10.0DES, CALB2
26polycystic ovary syndrome10.0CYP19A1, INHA
27synovial sarcoma10.0DES, CALB2
28peutz-jeghers syndrome10.0INHA, CYP19A1
29klinefelter's syndrome10.0CYP19A1, INHA
30benign mesothelioma10.0CALB2, DES
31uterine fibroid10.0PGR
32hyperandrogenism10.0CYP19A1
33myoma10.0PGR, CYP19A1
34estrogen excess10.0PGR, CYP19A1
35angiomyolipoma10.0PGR, DES
36leydig cell tumor10.0CALB2, CYP19A1, INHA
37fibromatosis10.0PGR, DES
38rhabdomyosarcoma10.0INHA, DES, CALB2
39granular cell tumor10.0CALB2, DES, INHA
40spindle cell carcinoma10.0DES, PGR
41adrenocortical carcinoma10.0CALB2, CYP19A1, INHA
42adrenal adenoma10.0INHA, CYP19A1, CALB2
43neurilemmoma10.0INHA, DES, CALB2
44malignant mixed mullerian tumor10.0PGR, DES
45li-fraumeni syndrome10.0PGR, CYP19A1
46phyllode tumor10.0MME, PGR
47renal clear cell carcinoma10.0MME, INHA, CALB2
48lymphangioleiomyomatosis10.0PGR, DES
49tubular adenocarcinoma10.0MME, PGR
50breast fibroadenoma10.0MME, PGR

Graphical network of the top 20 diseases related to Mixed Epithelial Stromal Tumour:



Diseases related to mixed epithelial stromal tumour

Clinical Features for Mixed Epithelial Stromal Tumour

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Drugs & Therapeutics for Mixed Epithelial Stromal Tumour

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Mixed Epithelial Stromal Tumour

Drug clinical trials:

Search ClinicalTrials for Mixed Epithelial Stromal Tumour

Search NIH Clinical Center for Mixed Epithelial Stromal Tumour

Search CenterWatch for Mixed Epithelial Stromal Tumour

Genetic Tests for Mixed Epithelial Stromal Tumour

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Anatomical Context for Mixed Epithelial Stromal Tumour

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32MalaCards
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MalaCards organs/tissues related to Mixed Epithelial Stromal Tumour:

32
Kidney

Animal Models for Mixed Epithelial Stromal Tumour or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Mixed Epithelial Stromal Tumour:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053769.1PGR, DES
2MP:00028738.1PGR, INHA, CYP19A1, CALB2

Publications for Mixed Epithelial Stromal Tumour

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50PubMed
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Articles related to Mixed Epithelial Stromal Tumour:

idTitleAuthorsYear
1
Exophytic benign mixed epithelial stromal tumour of the kidney: case report of a rare tumour entity. (20193076)
2010
2
Re: Rodolfo Montironi, Roberta Mazzuccelli, Antonio Lopez-Beltran, et al. Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? Eur Urol 2008;54:1237-46. (19167806)
2009
3
Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? (18006141)
2008
4
Editorial comment on: cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? (18006142)
2008
5
Mixed epithelial and stromal tumour of the kidney with luteinised ovarian stroma. (17213356)
2007
6
Mixed epithelial and stromal tumour (MEST) of the kidney: report of 14 cases with male and PEComatous variants and proposed histopathogenesis. (17454754)
2007
7
Mixed epithelial and stromal tumour of kidney. (16900720)
2006
8
Aggressive mixed epithelial-stromal tumour of the kidney treated with chemotherapy and radiotherapy. (15581546)
2004

Genetic Variations for Mixed Epithelial Stromal Tumour

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Expression for genes affiliated with Mixed Epithelial Stromal Tumour

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mixed Epithelial Stromal Tumour

Search GEO for disease gene expression data for Mixed Epithelial Stromal Tumour.

Pathways for genes affiliated with Mixed Epithelial Stromal Tumour

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37NCBI BioSystems Database
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Pathways related to Mixed Epithelial Stromal Tumour according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
18.6PGR, INHA, CYP19A1

Compounds for genes affiliated with Mixed Epithelial Stromal Tumour

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44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 24HMDB, 59Tocris Bioscience
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Compounds related to Mixed Epithelial Stromal Tumour according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1fatty acid4410.1INHA
2mucicarmine449.9DES, CALB2
3b 723449.7DES, CALB2
4acetylcholine44 49 28 11 2413.6CALB2, MME
5hematoxylin449.5INHA, DES, CALB2
6idoxifene449.5PGR, CYP19A1
7megestrol44 1110.5CYP19A1, PGR
8estradiol benzoate449.4PGR, CYP19A1
9nandrolone44 2410.4PGR, CYP19A1
10goserelin44 28 1111.4PGR, CYP19A1
11megestrol acetate449.4CYP19A1, PGR
12anastrozole44 1110.4CYP19A1, PGR
13capecitabine44 49 1111.4PGR, CYP19A1
14buserelin44 28 1111.4PGR, CYP19A1
15leuprolide acetate449.4PGR, CYP19A1
16exemestane49 44 59 1112.4CYP19A1, PGR
17bisphenol a449.4PGR, CYP19A1
18lapatinib44 49 1111.4PGR, CYP19A1
19clomiphene citrate449.4PGR, CYP19A1
20toremifene44 1110.4PGR, CYP19A1
21fulvestrant44 49 28 1112.4PGR, CYP19A1
22tibolone449.4CYP19A1, PGR
23danazol44 11 2411.4CYP19A1, PGR
24cyproteroneacetate449.3CYP19A1, PGR
25letrozole44 49 59 1112.3CYP19A1, PGR
26taxane449.3PGR, CYP19A1
27levonorgestrel44 59 28 1112.3CYP19A1, PGR
28adriamycin449.3MME, PGR, DES
29ribonucleic acid449.3MME, PGR, INHA
30flutamide44 59 1111.2PGR, CYP19A1
31steroidal449.2PGR, CYP19A1
32estrone sulfate44 2410.1PGR, CYP19A1
33diethylstilbestrol44 28 1111.1CYP19A1, PGR
343beta-hydroxysteroid449.1INHA, CYP19A1, PGR
3517beta-hydroxysteroid449.0CYP19A1, PGR
36progestin449.0PGR, DES, CYP19A1
37dihydrotestosterone44 28 11 2412.0DES, CYP19A1, PGR
38progestins448.9PGR, CYP19A1
39indomethacin44 59 28 1111.8CYP19A1, PGR, MME
40paclitaxel44 49 1110.7PGR, CALB2, CYP19A1
41raloxifene44 28 49 1111.7CYP19A1, PGR
42estradiol44 11 2410.6INHA, PGR, CYP19A1, DES
43gnrh448.5PGR, CYP19A1, INHA, MME
44doxorubicin44 49 1110.5MME, DES, CYP19A1, PGR
45paraffin448.4PGR, CALB2, INHA, MME, DES
46retinoic acid44 249.3PGR, CYP19A1, MME, DES
47progesterone44 59 28 11 2411.6PGR, INHA, MME, DES, CALB2, CYP19A1
48testosterone44 59 11 2410.6DES, CALB2, MME, CYP19A1, INHA, PGR
49steroid447.6CYP19A1, PGR, INHA, MME, DES, CALB2
50estrogen447.6CYP19A1, PGR, MME, INHA, DES, CALB2

GO Terms for genes affiliated with Mixed Epithelial Stromal Tumour

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Products for genes affiliated with Mixed Epithelial Stromal Tumour

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mixed Epithelial Stromal Tumour

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet