MCID: MXD010
MIFTS: 23

Mixed Epithelial Stromal Tumour malady

Summaries for Mixed Epithelial Stromal Tumour

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64Wikipedia, 33MalaCards
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Wikipedia:64 A cystic nephroma, also known as multilocular cystic nephroma, mixed epithelial stromal tumour (MEST)... more...

MalaCards: Mixed Epithelial Stromal Tumour is related to cystic nephroma and hemangioblastoma. An important gene associated with Mixed Epithelial Stromal Tumour is INHA (inhibin, alpha), and among its related pathways is Ovarian Infertility Genes. The compounds fatty acid and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include kidney, and related mouse phenotypes are homeostasis/metabolism and normal.

Aliases & Classifications for Mixed Epithelial Stromal Tumour

Sources:
8Disease Ontology, 61UMLS, 40NCIt
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Aliases & Descriptions:

mixed epithelial stromal tumour 8


External Ids:

Disease Ontology8 DOID:5088
NCIt40 C37265

Related Diseases for Mixed Epithelial Stromal Tumour

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Mixed Epithelial Stromal Tumour via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 71)
idRelated DiseaseScoreTop Affiliating Genes
1cystic nephroma10.3
2hemangioblastoma10.0INHA
3angiosarcoma10.0CALB2
4thymoma10.0CALB2
5germinoma10.0INHA
6adenomatoid tumor10.0CALB2
7desmoid tumor10.0DES
8congestive heart failure10.0MME
9colon cancer10.0CALB2
10leiomyomatosis10.0PGR
11adenofibroma10.0INHA, CALB2
12lipoma10.0DES
13hypertension10.0MME
14adenoma10.0CALB2, INHA
15ductal carcinoma in situ10.0PGR
16pheochromocytoma10.0INHA, CALB2
17sex cord-gonadal stromal tumor10.0CALB2, INHA
18seminoma10.0INHA, CALB2
19sarcoma10.0DES, CALB2
20chordoma10.0INHA, DES
21cryptorchidism10.0CYP19A1
22cystadenoma10.0MME, INHA
23aorta atresia10.0CYP19A1, INHA
24liposarcoma10.0CALB2, DES
25malignant mesothelioma10.0DES, CALB2
26polycystic ovary syndrome10.0CYP19A1, INHA
27synovial sarcoma10.0DES, CALB2
28peutz-jeghers syndrome10.0INHA, CYP19A1
29klinefelter's syndrome10.0CYP19A1, INHA
30benign mesothelioma10.0CALB2, DES
31uterine fibroid10.0PGR
32hyperandrogenism10.0CYP19A1
33myoma10.0PGR, DES
34estrogen excess10.0PGR, CYP19A1
35leydig cell tumor10.0CALB2, CYP19A1, INHA
36angiomyolipoma10.0PGR, DES
37rhabdomyosarcoma10.0INHA, DES, CALB2
38fibromatosis10.0PGR, DES
39granular cell tumor10.0CALB2, DES, INHA
40adrenocortical carcinoma10.0CALB2, CYP19A1, INHA
41spindle cell carcinoma10.0DES, PGR
42adrenal adenoma10.0INHA, CYP19A1, CALB2
43neurilemmoma10.0INHA, DES, CALB2
44malignant mixed mullerian tumor10.0PGR, DES
45li-fraumeni syndrome10.0PGR, CYP19A1
46phyllode tumor10.0MME, PGR
47renal clear cell carcinoma10.0MME, INHA, CALB2
48lymphangioleiomyomatosis10.0PGR, DES
49tubular adenocarcinoma10.0MME, PGR
50breast fibroadenoma10.0MME, PGR

Graphical network of the top 20 diseases related to Mixed Epithelial Stromal Tumour:



Diseases related to mixed epithelial stromal tumour

Clinical Features for Mixed Epithelial Stromal Tumour

Drugs & Therapeutics for Mixed Epithelial Stromal Tumour

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Mixed Epithelial Stromal Tumour

Drug clinical trials:

Search ClinicalTrials for Mixed Epithelial Stromal Tumour

Search NIH Clinical Center for Mixed Epithelial Stromal Tumour

Search CenterWatch for Mixed Epithelial Stromal Tumour

Genetic Tests for Mixed Epithelial Stromal Tumour

Anatomical Context for Mixed Epithelial Stromal Tumour

Sources:
33MalaCards
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MalaCards organs/tissues related to Mixed Epithelial Stromal Tumour:

33
Kidney

Animal Models for Mixed Epithelial Stromal Tumour or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Mixed Epithelial Stromal Tumour:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053769.1PGR, DES
2MP:00028738.1PGR, INHA, CYP19A1, CALB2

Publications for Mixed Epithelial Stromal Tumour

Sources:
51PubMed
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Articles related to Mixed Epithelial Stromal Tumour:

idTitleAuthorsYear
1
Exophytic benign mixed epithelial stromal tumour of the kidney: case report of a rare tumour entity. (20193076)
2010
2
Re: Rodolfo Montironi, Roberta Mazzuccelli, Antonio Lopez-Beltran, et al. Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? Eur Urol 2008;54:1237-46. (19167806)
2009
3
Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? (18006141)
2008
4
Editorial comment on: cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity? (18006142)
2008
5
Mixed epithelial and stromal tumour of the kidney with luteinised ovarian stroma. (17213356)
2007
6
Mixed epithelial and stromal tumour (MEST) of the kidney: report of 14 cases with male and PEComatous variants and proposed histopathogenesis. (17454754)
2007
7
Mixed epithelial and stromal tumour of kidney. (16900720)
2006
8
Aggressive mixed epithelial-stromal tumour of the kidney treated with chemotherapy and radiotherapy. (15581546)
2004

Genetic Variations for Mixed Epithelial Stromal Tumour

Expression for genes affiliated with Mixed Epithelial Stromal Tumour

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mixed Epithelial Stromal Tumour

Search GEO for disease gene expression data for Mixed Epithelial Stromal Tumour.

Pathways for genes affiliated with Mixed Epithelial Stromal Tumour

Sources:
38NCBI BioSystems Database
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Pathways related to Mixed Epithelial Stromal Tumour according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
18.6PGR, INHA, CYP19A1

Compounds for genes affiliated with Mixed Epithelial Stromal Tumour

Sources:
45Novoseek, 50PharmGKB, 29IUPHAR, 11DrugBank, 24HMDB, 60Tocris Bioscience
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Compounds related to Mixed Epithelial Stromal Tumour according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1fatty acid4510.1INHA
2mucicarmine459.9CALB2, DES
3b 723459.7DES, CALB2
4acetylcholine45 50 29 11 2413.6MME, CALB2
5hematoxylin459.5CALB2, DES, INHA
6idoxifene459.5PGR, CYP19A1
7megestrol45 1110.5PGR, CYP19A1
8estradiol benzoate459.4CYP19A1, PGR
9nandrolone45 2410.4CYP19A1, PGR
10goserelin45 29 1111.4PGR, CYP19A1
11megestrol acetate459.4CYP19A1, PGR
12anastrozole45 1110.4PGR, CYP19A1
13buserelin45 29 1111.4CYP19A1, PGR
14capecitabine45 50 1111.4CYP19A1, PGR
15leuprolide acetate459.4CYP19A1, PGR
16exemestane50 45 60 1112.4PGR, CYP19A1
17bisphenol a459.4PGR, CYP19A1
18lapatinib45 50 1111.4CYP19A1, PGR
19toremifene45 1110.4PGR, CYP19A1
20clomiphene citrate459.4PGR, CYP19A1
21tibolone459.4CYP19A1, PGR
22fulvestrant45 50 29 1112.4CYP19A1, PGR
23danazol45 11 2411.4CYP19A1, PGR
24cyproteroneacetate459.3PGR, CYP19A1
25taxane459.3PGR, CYP19A1
26letrozole45 50 60 1112.3PGR, CYP19A1
27levonorgestrel45 60 29 1112.3PGR, CYP19A1
28adriamycin459.3MME, PGR, DES
29ribonucleic acid459.3MME, PGR, INHA
30flutamide45 60 1111.2CYP19A1, PGR
31steroidal459.2PGR, CYP19A1
32estrone sulfate45 2410.1PGR, CYP19A1
33diethylstilbestrol45 29 1111.1CYP19A1, PGR
343beta-hydroxysteroid459.1CYP19A1, INHA, PGR
3517beta-hydroxysteroid459.0PGR, CYP19A1
36progestin459.0DES, CYP19A1, PGR
37dihydrotestosterone45 29 11 2412.0PGR, CYP19A1, DES
38progestins458.9PGR, CYP19A1
39indomethacin45 60 29 1111.8CYP19A1, PGR, MME
40paclitaxel45 50 1110.7PGR, CYP19A1, CALB2
41raloxifene45 29 50 1111.7PGR, CYP19A1
42estradiol45 11 2410.6PGR, INHA, CYP19A1, DES
43gnrh458.5MME, PGR, INHA, CYP19A1
44doxorubicin45 50 1110.5MME, PGR, CYP19A1, DES
45paraffin458.4CALB2, DES, INHA, PGR, MME
46retinoic acid45 249.3DES, CYP19A1, PGR, MME
47progesterone45 60 29 11 2411.6MME, PGR, INHA, CYP19A1, DES, CALB2
48testosterone45 60 11 2410.6CALB2, DES, CYP19A1, INHA, PGR, MME
49steroid457.6CALB2, DES, CYP19A1, INHA, PGR, MME
50estrogen457.6CALB2, DES, CYP19A1, INHA, PGR, MME

GO Terms for genes affiliated with Mixed Epithelial Stromal Tumour

Products for genes affiliated with Mixed Epithelial Stromal Tumour

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mixed Epithelial Stromal Tumour

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet