MCID: MXD026
MIFTS: 35

Mixed Glioma malady

Neuronal diseases, Cancer diseases categories

Aliases & Classifications for Mixed Glioma

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 61UMLS, 33MeSH, 56SNOMED-CT, 39NCIt
See all sources

Aliases & Descriptions for Mixed Glioma:

Name: Mixed Glioma 8 10 44
Mixed Gliomas 8 61
 
Mixed Neuroglial Tumor 8


Classifications:



External Ids:

Disease Ontology8 DOID:5076
MeSH33 D005910
SNOMED-CT56 22217002, 443937008
NCIt39 C3903

Summaries for Mixed Glioma

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MalaCards based summary: Mixed Glioma, also known as mixed gliomas, is related to oligodendroglioma and anaplastic oligodendroglioma. An important gene associated with Mixed Glioma is GFAP (glial fibrillary acidic protein), and among its related pathways are Spinal Cord Injury and Cytoplasmic microtubules. The compounds pentobarbital and phenylbutyrate have been mentioned in the context of this disorder. Affiliated tissues include brain, cerebellum and endothelial, and related mouse phenotypes are muscle and cardiovascular system.

Related Diseases for Mixed Glioma

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Diseases related to Mixed Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
idRelated DiseaseScoreTop Affiliating Genes
1oligodendroglioma30.7GFAP, PDGFRA
2anaplastic oligodendroglioma30.4GFAP, PDGFRA
3glioblastoma multiforme30.3GFAP, PDGFRA
4rhabdomyosarcoma30.2PDGFRA, VIM
5astrocytoma30.0PDGFRA, VIM, GFAP
6sarcoma29.8PDGFRA, HSPA4, VIM
7neurilemmoma10.4GFAP
8syringoma10.4GFAP
9choroid plexus papilloma10.4GFAP
10subependymal giant cell astrocytoma10.4GFAP
11giant cell glioblastoma10.4GFAP
12adult brainstem mixed glioma10.4
13perineurioma10.4VIM
14oligoastrocytoma10.3
15rhabdoid meningioma10.2GFAP, VIM
16astroblastoma10.2GFAP, VIM
17myoepithelioma10.2VIM, GFAP
18cataract10.2HSPA4
19pleomorphic adenoma10.2VIM, GFAP
20endometrial stromal sarcoma10.2VIM, PDGFRA
21grade iii astrocytoma10.2GFAP, PDGFRA
22tuberous sclerosis10.2GFAP, VIM
23angiosarcoma10.2VIM, PDGFRA
24malignant peripheral nerve sheath tumor10.2PDGFRA, VIM
25neurofibroma10.2PDGFRA, VIM
26gastrointestinal stromal tumor10.2VIM, PDGFRA
27leiomyosarcoma10.2PDGFRA, VIM
28leiomyoma10.1PDGFRA, VIM
29ewing sarcoma10.1VIM, PDGFRA
30chondrosarcoma10.1VIM, PDGFRA
31meningioma, familial10.1VIM, GFAP
32medulloblastoma10.1PDGFRA, GFAP
33charcot-marie-tooth disease10.1
34mixed oligodendroglioma-astrocytoma10.1
35germinoma10.1
36tooth disease10.1
37anaplastic oligoastrocytoma10.1
38glioblastoma10.1
39endotheliitis10.1
40toxic encephalopathy10.0HSPA4, GFAP
41brain disease10.0GFAP, HSPA4
42fibrosarcoma10.0PDGFRA, VIM
43chordoma10.0PDGFRA, VIM, GFAP
44ependymoma10.0GFAP, PDGFRA, VIM
45malignant glioma9.9GFAP, PDGFRA
46dementia9.9GFAP, HSPA4
47leukemia, chronic myeloid9.9HSPA4, PDGFRA
48vascular disease9.9GFAP, HSPA4
49tongue squamous cell carcinoma9.8VIM, HSPA4, PDGFRA
50melanoma9.7HSPA4, PDGFRA, VIM

Graphical network of the top 20 diseases related to Mixed Glioma:



Diseases related to mixed glioma

Symptoms for Mixed Glioma

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Drugs & Therapeutics for Mixed Glioma

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Drug clinical trials:

Search ClinicalTrials for Mixed Glioma

Search NIH Clinical Center for Mixed Glioma

Genetic Tests for Mixed Glioma

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Anatomical Context for Mixed Glioma

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MalaCards organs/tissues related to Mixed Glioma:

31
Brain, Cerebellum, Endothelial

Animal Models for Mixed Glioma or affiliated genes

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MGI Mouse Phenotypes related to Mixed Glioma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.1GFAP, VIM, PDGFRA, HRC
2MP:00053858.1GFAP, VIM, PDGFRA, HRC
3MP:00053788.1HRC, PDGFRA, VIM, GFAP
4MP:00053848.1PDGFRA, VIM, HSPA4, GFAP
5MP:00036317.9GFAP, HSPA4, VIM, PDGFRA
6MP:00053867.6HRC, PDGFRA, VIM, HSPA4, GFAP

Publications for Mixed Glioma

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Articles related to Mixed Glioma:

(show all 13)
idTitleAuthorsYear
1
Mixed glioma with molecular features of composite oligodendroglioma and astrocytoma: a true "oligoastrocytoma"? (25359109)
2014
2
Mixed Glioma (Oligoastrocytoma) in the Brain ofA an African Hedgehog (Atelerix albiventris). (25172052)
2014
3
Anaplastic mixed gliomas and anaplastic oligodendroglioma in children: results from the CCG 945 experience. (17252186)
2007
4
Monitoring the effect of chemotherapy in a mixed glioma by C-11-methionine PET. (12889176)
2003
5
Long-term outcome of low-grade oligodendroglioma and mixed glioma. (10751254)
2000
6
Can experimental models of rodent implantation glioma be improved? A study of pure and mixed glioma cell line tumours. (9524101)
1998
7
Exophytic malignant brainstem mixed glioma in an adult: a case report. (9524090)
1998
8
Spontaneous hemorrhage in a mixed glioma of the cerebellum: case report. (3748360)
1986
9
Combined occurrence of third ventricular germinoma and hypothalamic mixed glioma. (3713193)
1986
10
Mixed glioma of the cerebellopontine angle. (3878094)
1985
11
Immunohistochemical detection of factor VIII/von Willebrand factor in hyperplastic endothelial cells in glioblastoma multiforme and mixed glioma-sarcoma. (6286891)
1982
12
Mixed glioma and rhabdomyosarcoma in brain of a wild deer. (929897)
1977
13
Mixed glioma, multiple sclerosis, and Charcot-Marie-Tooth disease. (5050901)
1972

Variations for Mixed Glioma

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Expression for genes affiliated with Mixed Glioma

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Search GEO for disease gene expression data for Mixed Glioma.

Pathways for genes affiliated with Mixed Glioma

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Pathways related to Mixed Glioma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.2GFAP, VIM
2
Show member pathways
8.7PDGFRA, VIM, GFAP
3
Show member pathways
8.6PDGFRA, VIM, HSPA4

Compounds for genes affiliated with Mixed Glioma

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Compounds related to Mixed Glioma according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idCompoundScoreTop Affiliating Genes
1pentobarbital44 1110.9HSPA4, GFAP
2phenylbutyrate449.9GFAP, HSPA4
3silver449.8GFAP, HSPA4
4kainate44 2810.7GFAP, HSPA4
5eosin449.6GFAP, VIM
6s 100449.6VIM, GFAP
7reticulin449.6GFAP, VIM
8retinaldehyde449.6VIM, GFAP
9silicone449.6VIM, GFAP
10streptozotocin449.5VIM, GFAP
11hematoxylin449.5VIM, GFAP
12ganciclovir44 1110.5GFAP, VIM
13inositol449.5GFAP, HSPA4
14ganglioside449.5GFAP, VIM
15dbc-amp449.5GFAP, VIM
16chondroitin sulfate44 2410.4GFAP, VIM
17nocodazole44 1110.4VIM, HSPA4
18cytarabine44 50 1111.3GFAP, VIM
19adriamycin449.2VIM, HSPA4
20neomycin449.1GFAP, HSPA4, VIM
21cocaine44 1110.1VIM, GFAP, HSPA4
22bromodeoxyuridine449.1GFAP, HSPA4, VIM
23isoproterenol44 1110.1GFAP, HSPA4, VIM
24agar449.1VIM, HSPA4, GFAP
255-hydroxytryptamine449.1GFAP, VIM
26butyrate449.1VIM, HSPA4, GFAP
27methionine449.1GFAP, HSPA4, VIM
28nmda44 2810.1GFAP, HSPA4, VIM
29paclitaxel44 50 1111.1GFAP, HSPA4, VIM
30acetylcholine44 50 28 24 1113.1GFAP, HSPA4, VIM
31estradiol44 24 1111.1HSPA4, GFAP, VIM
32genistein44 28 60 1 24 1114.1HSPA4, GFAP, VIM
33glutamine449.0HSPA4, VIM, GFAP
34iron44 2410.0GFAP, VIM, HSPA4
35lactate449.0GFAP, HSPA4, VIM
36creatinine449.0HSPA4, GFAP, VIM
37adenylate449.0GFAP, HSPA4, VIM
38cycloheximide449.0GFAP, HSPA4, VIM
39progesterone44 28 60 24 1113.0HSPA4, VIM, GFAP
40testosterone44 60 24 1112.0HSPA4, VIM, GFAP
41dexamethasone44 50 28 1111.9HSPA4, VIM, GFAP
42glutamate448.9GFAP, HSPA4, VIM
43tgf beta1448.8VIM, PDGFRA
44alanine448.8VIM, GFAP, HSPA4
45estrogen448.7VIM, GFAP, PDGFRA
46paraffin448.6GFAP, HSPA4, VIM, PDGFRA
47aspartate448.6GFAP, VIM, HSPA4, PDGFRA
48vegf448.6PDGFRA, VIM, HSPA4, GFAP
49retinoic acid44 249.6GFAP, VIM, HSPA4, PDGFRA
50atp44 289.6HSPA4, GFAP, VIM, PDGFRA

GO Terms for genes affiliated with Mixed Glioma

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Cellular components related to Mixed Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.2VIM, GFAP

Biological processes related to Mixed Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:00600209.2VIM, GFAP
2negative regulation of neuron projection developmentGO:00109779.2VIM, GFAP
3astrocyte developmentGO:00140029.1VIM, GFAP
4intermediate filament organizationGO:00451098.9VIM, GFAP

Molecular functions related to Mixed Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.2VIM, GFAP

Sources for Mixed Glioma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet