MCID: MXD026
MIFTS: 35

Mixed Glioma malady

Neuronal diseases, Cancer diseases categories

Aliases & Classifications for Mixed Glioma

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 33MeSH, 55SNOMED-CT, 38NCIt
See all sources

Mixed Glioma, Aliases & Descriptions:

Name: Mixed Glioma 9 11 43
Mixed Gliomas 9 60
 
Mixed Neuroglial Tumor 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


External Ids:

Disease Ontology9 DOID:5076
MeSH33 D005910
SNOMED-CT55 22217002, 443937008
NCIt38 C3903

Summaries for Mixed Glioma

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MalaCards based summary: Mixed Glioma, also known as mixed gliomas, is related to oligodendroglioma and anaplastic oligodendroglioma. An important gene associated with Mixed Glioma is GFAP (glial fibrillary acidic protein), and among its related pathways are Spinal Cord Injury and Cytoplasmic microtubules. The compounds pentobarbital and phenylbutyrate have been mentioned in the context of this disorder. Affiliated tissues include brain, cerebellum and endothelial, and related mouse phenotypes are muscle and cardiovascular system.

Related Diseases for Mixed Glioma

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Diseases related to Mixed Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
idRelated DiseaseScoreTop Affiliating Genes
1oligodendroglioma30.7GFAP, PDGFRA
2anaplastic oligodendroglioma30.4GFAP, PDGFRA
3glioblastoma multiforme30.3GFAP, PDGFRA
4rhabdomyosarcoma30.2PDGFRA, VIM
5astrocytoma30.0PDGFRA, VIM, GFAP
6sarcoma29.8PDGFRA, HSPA4, VIM
7neurilemmoma10.4GFAP
8syringoma10.4GFAP
9choroid plexus papilloma10.4GFAP
10subependymal giant cell astrocytoma10.4GFAP
11giant cell glioblastoma10.4GFAP
12adult brainstem mixed glioma10.4
13perineurioma10.4VIM
14oligoastrocytoma10.3
15rhabdoid meningioma10.2GFAP, VIM
16astroblastoma10.2GFAP, VIM
17myoepithelioma10.2VIM, GFAP
18cataract10.2HSPA4
19pleomorphic adenoma10.2VIM, GFAP
20endometrial stromal sarcoma10.2VIM, PDGFRA
21grade iii astrocytoma10.2GFAP, PDGFRA
22tuberous sclerosis10.2GFAP, VIM
23angiosarcoma10.2VIM, PDGFRA
24malignant peripheral nerve sheath tumor10.2PDGFRA, VIM
25neurofibroma10.2PDGFRA, VIM
26gastrointestinal stromal tumor10.2VIM, PDGFRA
27leiomyosarcoma10.2PDGFRA, VIM
28leiomyoma10.1PDGFRA, VIM
29ewing sarcoma10.1VIM, PDGFRA
30chondrosarcoma10.1VIM, PDGFRA
31meningioma, familial10.1VIM, GFAP
32medulloblastoma10.1PDGFRA, GFAP
33charcot-marie-tooth disease10.1
34mixed oligodendroglioma-astrocytoma10.1
35germinoma10.1
36tooth disease10.1
37anaplastic oligoastrocytoma10.1
38glioblastoma10.1
39endotheliitis10.1
40toxic encephalopathy10.0HSPA4, GFAP
41brain disease10.0GFAP, HSPA4
42fibrosarcoma10.0PDGFRA, VIM
43chordoma10.0PDGFRA, VIM, GFAP
44ependymoma10.0GFAP, PDGFRA, VIM
45malignant glioma9.9GFAP, PDGFRA
46dementia9.9GFAP, HSPA4
47leukemia, chronic myeloid9.9HSPA4, PDGFRA
48vascular disease9.9GFAP, HSPA4
49tongue squamous cell carcinoma9.8VIM, HSPA4, PDGFRA
50melanoma9.7HSPA4, PDGFRA, VIM

Graphical network of the top 20 diseases related to Mixed Glioma:



Diseases related to mixed glioma

Symptoms for Mixed Glioma

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Drugs & Therapeutics for Mixed Glioma

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Drug clinical trials:

Search ClinicalTrials for Mixed Glioma

Search NIH Clinical Center for Mixed Glioma

Genetic Tests for Mixed Glioma

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Anatomical Context for Mixed Glioma

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MalaCards organs/tissues related to Mixed Glioma:

31
Brain, Cerebellum, Endothelial

Animal Models for Mixed Glioma or affiliated genes

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MGI Mouse Phenotypes related to Mixed Glioma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.1GFAP, VIM, PDGFRA, HRC
2MP:00053858.1GFAP, VIM, PDGFRA, HRC
3MP:00053788.1HRC, PDGFRA, VIM, GFAP
4MP:00053848.1PDGFRA, VIM, HSPA4, GFAP
5MP:00036317.9GFAP, HSPA4, VIM, PDGFRA
6MP:00053867.6HRC, PDGFRA, VIM, HSPA4, GFAP

Publications for Mixed Glioma

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Articles related to Mixed Glioma:

(show all 13)
idTitleAuthorsYear
1
Mixed glioma with molecular features of composite oligodendroglioma and astrocytoma: a true "oligoastrocytoma"? (25359109)
2014
2
Mixed Glioma (Oligoastrocytoma) in the Brain ofA an African Hedgehog (Atelerix albiventris). (25172052)
2014
3
Anaplastic mixed gliomas and anaplastic oligodendroglioma in children: results from the CCG 945 experience. (17252186)
2007
4
Monitoring the effect of chemotherapy in a mixed glioma by C-11-methionine PET. (12889176)
2003
5
Long-term outcome of low-grade oligodendroglioma and mixed glioma. (10751254)
2000
6
Can experimental models of rodent implantation glioma be improved? A study of pure and mixed glioma cell line tumours. (9524101)
1998
7
Exophytic malignant brainstem mixed glioma in an adult: a case report. (9524090)
1998
8
Spontaneous hemorrhage in a mixed glioma of the cerebellum: case report. (3748360)
1986
9
Combined occurrence of third ventricular germinoma and hypothalamic mixed glioma. (3713193)
1986
10
Mixed glioma of the cerebellopontine angle. (3878094)
1985
11
Immunohistochemical detection of factor VIII/von Willebrand factor in hyperplastic endothelial cells in glioblastoma multiforme and mixed glioma-sarcoma. (6286891)
1982
12
Mixed glioma and rhabdomyosarcoma in brain of a wild deer. (929897)
1977
13
Mixed glioma, multiple sclerosis, and Charcot-Marie-Tooth disease. (5050901)
1972

Variations for Mixed Glioma

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Expression for genes affiliated with Mixed Glioma

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Search GEO for disease gene expression data for Mixed Glioma.

Pathways for genes affiliated with Mixed Glioma

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Pathways related to Mixed Glioma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.2GFAP, VIM
2
Show member pathways
8.7PDGFRA, VIM, GFAP
3
Show member pathways
8.6PDGFRA, VIM, HSPA4

Compounds for genes affiliated with Mixed Glioma

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Compounds related to Mixed Glioma according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idCompoundScoreTop Affiliating Genes
1pentobarbital43 1210.9HSPA4, GFAP
2phenylbutyrate439.9GFAP, HSPA4
3silver439.8HSPA4, GFAP
4kainate43 2810.7HSPA4, GFAP
5eosin439.6VIM, GFAP
6s 100439.6VIM, GFAP
7reticulin439.6GFAP, VIM
8retinaldehyde439.6VIM, GFAP
9silicone439.6GFAP, VIM
10streptozotocin439.5VIM, GFAP
11hematoxylin439.5GFAP, VIM
12ganciclovir43 1210.5VIM, GFAP
13inositol439.5HSPA4, GFAP
14ganglioside439.5GFAP, VIM
15dbc-amp439.5VIM, GFAP
16chondroitin sulfate43 2410.4VIM, GFAP
17nocodazole43 1210.4VIM, HSPA4
18cytarabine43 49 1211.3VIM, GFAP
19adriamycin439.2VIM, HSPA4
20neomycin439.1VIM, HSPA4, GFAP
21cocaine43 1210.1VIM, HSPA4, GFAP
22bromodeoxyuridine439.1GFAP, HSPA4, VIM
23isoproterenol43 1210.1GFAP, HSPA4, VIM
24agar439.1VIM, HSPA4, GFAP
255-hydroxytryptamine439.1VIM, GFAP
26butyrate439.1GFAP, HSPA4, VIM
27methionine439.1VIM, HSPA4, GFAP
28nmda43 2810.1VIM, HSPA4, GFAP
29paclitaxel43 49 1211.1VIM, HSPA4, GFAP
30acetylcholine43 49 28 24 1213.1VIM, HSPA4, GFAP
31estradiol43 24 1211.1VIM, HSPA4, GFAP
32genistein43 28 59 2 24 1214.1GFAP, HSPA4, VIM
33glutamine439.0VIM, HSPA4, GFAP
34iron43 2410.0VIM, HSPA4, GFAP
35lactate439.0GFAP, HSPA4, VIM
36creatinine439.0VIM, HSPA4, GFAP
37adenylate439.0GFAP, HSPA4, VIM
38cycloheximide439.0VIM, HSPA4, GFAP
39progesterone43 28 59 24 1213.0VIM, HSPA4, GFAP
40testosterone43 59 24 1212.0VIM, HSPA4, GFAP
41dexamethasone43 49 28 1211.9GFAP, HSPA4, VIM
42glutamate438.9GFAP, HSPA4, VIM
43tgf beta1438.8PDGFRA, VIM
44alanine438.8VIM, HSPA4, GFAP
45estrogen438.7GFAP, VIM, PDGFRA
46paraffin438.6PDGFRA, VIM, HSPA4, GFAP
47aspartate438.6GFAP, HSPA4, VIM, PDGFRA
48vegf438.6PDGFRA, VIM, HSPA4, GFAP
49retinoic acid43 249.6PDGFRA, VIM, HSPA4, GFAP
50atp43 289.6GFAP, HSPA4, VIM, PDGFRA

GO Terms for genes affiliated with Mixed Glioma

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Cellular components related to Mixed Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.2VIM, GFAP

Biological processes related to Mixed Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:00600209.2VIM, GFAP
2negative regulation of neuron projection developmentGO:00109779.2VIM, GFAP
3astrocyte developmentGO:00140029.1VIM, GFAP
4intermediate filament organizationGO:00451098.9VIM, GFAP

Molecular functions related to Mixed Glioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.2VIM, GFAP

Products for genes affiliated with Mixed Glioma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Mixed Glioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet