MCID: MXD006
MIFTS: 25

Mixed Liposarcoma

Categories: Cancer diseases

Aliases & Classifications for Mixed Liposarcoma

MalaCards integrated aliases for Mixed Liposarcoma:

Name: Mixed Liposarcoma 12 14 69
Mixed-Type Liposarcoma 12 14
Myxoid/round Cell Liposarcoma 69

Classifications:



External Ids:

Disease Ontology 12 DOID:5703 DOID:5709
NCIt 46 C4253 C27781
SNOMED-CT 64 11073003

Summaries for Mixed Liposarcoma

MalaCards based summary : Mixed Liposarcoma, also known as mixed-type liposarcoma, is related to liposarcoma and ring chromosome 7. An important gene associated with Mixed Liposarcoma is MDM2 (MDM2 Proto-Oncogene), and among its related pathways/superpathways are Viral carcinogenesis and Transcriptional misregulation in cancer.

Related Diseases for Mixed Liposarcoma

Diseases related to Mixed Liposarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 liposarcoma 28.6 CD34 CDK4 DDIT3 FUS MB MDM2
2 ring chromosome 7 10.5 CDK4 MDM2
3 undifferentiated embryonal sarcoma of the liver 10.5 CDK4 MDM2
4 infiltrating angiolipoma 10.5 CDK4 MDM2
5 spindle cell lipoma 10.5 CDK4 MDM2
6 bone osteosarcoma 10.5 CDK4 MDM2
7 lipoblastoma 10.5 CDK4 MDM2
8 mesenchymoma 10.5 MB MDM2
9 malignant fibrous histiocytoma of bone 10.4 CDK4 MDM2
10 periosteal chondrosarcoma 10.4 CDK4 MDM2
11 periosteal osteogenic sarcoma 10.4 CDK4 MDM2
12 well-differentiated liposarcoma 10.4 CDK4 MDM2
13 dedifferentiated liposarcoma 10.4 CDK4 MDM2
14 small cell sarcoma 10.4 CDK4 MDM2
15 juxtacortical osteosarcoma 10.4 CDK4 MDM2
16 embryonal sarcoma 10.4 CDK4 MDM2
17 adult fibrosarcoma 10.4 MB PDGFB
18 myxofibrosarcoma 10.3 CREB3L2 FUS
19 uterine sarcoma 10.3 MB MDM2
20 hemangiopericytoma, malignant 10.3 HBA1 MDM2
21 lipomatosis, multiple 10.3 CDK4 FUS MDM2
22 ovary sarcoma 10.3 CD34 HBA1
23 ovarian angiosarcoma 10.3 CD34 HBA1
24 heart sarcoma 10.3 CREB3L2 MDM2
25 intravascular fasciitis 10.3 CD34 HBA1
26 malignant mesenchymoma 10.3 CDK4 MB MDM2
27 pediatric angiosarcoma 10.3 CD34 HBA1
28 thyroid angiosarcoma 10.3 CD34 HBA1
29 neurogenic arthropathy 10.2 CD34 HBA1
30 peripheral osteosarcoma 10.2 CDK4 MDM2
31 rhabdomyosarcoma 2 10.2 CDK4 MB MDM2
32 leiomyosarcoma 10.2 CDK4 MB MDM2
33 pericardium cancer 10.2 HBA1 MB
34 spleen angiosarcoma 10.2 CD34 HBA1
35 bone epithelioid hemangioma 10.2 CD34 HBA1
36 thyroid sarcoma 10.2 CD34 HBA1
37 hobnail hemangioma 10.2 CD34 HBA1
38 breast angiosarcoma 10.2 CD34 HBA1
39 conventional angiosarcoma 10.2 CD34 HBA1
40 venous hemangioma 10.2 CD34 HBA1
41 interstitial emphysema 10.2 CD34 HBA1
42 cellular schwannoma 10.2 CD34 MDM2
43 rhabdomyosarcoma 10.2 CDK4 MB MDM2
44 chorioangioma 10.2 CD34 HBA1
45 nominal aphasia 10.2 FUS PDGFB
46 integumentary system benign neoplasm 10.1 CD34 HBA1
47 lymphangiosarcoma 10.1 CD34 HBA1
48 spindle cell synovial sarcoma 10.1 CD34 MB
49 malignant fibroxanthoma 10.1 CDK4 MDM2
50 deep angioma 10.1 CD34 CREB3L2

Graphical network of the top 20 diseases related to Mixed Liposarcoma:



Diseases related to Mixed Liposarcoma

Symptoms & Phenotypes for Mixed Liposarcoma

Drugs & Therapeutics for Mixed Liposarcoma

Search Clinical Trials , NIH Clinical Center for Mixed Liposarcoma

Genetic Tests for Mixed Liposarcoma

Anatomical Context for Mixed Liposarcoma

Publications for Mixed Liposarcoma

Articles related to Mixed Liposarcoma:

# Title Authors Year
1
Spermatic cord mixed liposarcoma. Case report and review of the literature. ( 18273513 )
2008
2
Radiologically and histologically mixed liposarcoma: a report of two biphasic cases. ( 14594943 )
2003

Variations for Mixed Liposarcoma

Expression for Mixed Liposarcoma

Search GEO for disease gene expression data for Mixed Liposarcoma.

Pathways for Mixed Liposarcoma

Pathways related to Mixed Liposarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.74 CDK4 CREB3L2 MDM2
2 11.6 DDIT3 FUS MDM2
3 11.18 CDK4 MDM2 PDGFB
4 10.83 CDK4 MDM2
5 9.53 HBA1 MB

GO Terms for Mixed Liposarcoma

Biological processes related to Mixed Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heart development GO:0007507 9.61 MB MDM2 PDGFB
2 negative regulation of gene expression GO:0010629 9.54 CD34 MDM2 PDGFB
3 positive regulation of cell cycle GO:0045787 9.46 CDK4 MDM2
4 cellular response to organic substance GO:0071310 9.4 CD68 MDM2
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.32 MDM2 PDGFB
6 negative regulation of cell cycle arrest GO:0071157 9.26 CDK4 MDM2
7 oxygen transport GO:0015671 9.16 HBA1 MB
8 positive regulation of vascular associated smooth muscle cell migration GO:1904754 8.96 MDM2 PDGFB
9 paracrine signaling GO:0038001 8.62 CD34 PDGFB

Molecular functions related to Mixed Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen carrier activity GO:0005344 8.62 HBA1 MB

Sources for Mixed Liposarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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