MCID: MXD031
MIFTS: 27

Mixed-Type Liposarcoma malady

Summaries for Mixed-Type Liposarcoma

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32MalaCards
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MalaCards: Mixed-Type Liposarcoma, also known as mixed liposarcoma, is related to liposarcoma and myxoid liposarcoma. An important gene associated with Mixed-Type Liposarcoma is FUS (fused in sarcoma), and among its related pathways are Transcriptional misregulation in cancer and Chks in Checkpoint Regulation. The compounds fludarabine and roscovitine have been mentioned in the context of this disorder. Related mouse phenotype reproductive system.

Aliases & Classifications for Mixed-Type Liposarcoma

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8Disease Ontology, 60UMLS, 39NCIt, 56SNOMED-CT
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Aliases & Descriptions:

mixed-type liposarcoma 8
mixed liposarcoma 8 60


External Ids:

Disease Ontology8 DOID:5709, DOID:5703
SNOMED-CT56 11073003

Related Diseases for Mixed-Type Liposarcoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Mixed-Type Liposarcoma:



Diseases related to mixed-type liposarcoma

Clinical Features for Mixed-Type Liposarcoma

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Drugs & Therapeutics for Mixed-Type Liposarcoma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Mixed-Type Liposarcoma

Drug clinical trials:

Search ClinicalTrials for Mixed-Type Liposarcoma

Search NIH Clinical Center for Mixed-Type Liposarcoma

Search CenterWatch for Mixed-Type Liposarcoma

Genetic Tests for Mixed-Type Liposarcoma

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Anatomical Context for Mixed-Type Liposarcoma

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Animal Models for Mixed-Type Liposarcoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Mixed-Type Liposarcoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.5FUS, CDK4, MDM2

Publications for Mixed-Type Liposarcoma

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50PubMed
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Articles related to Mixed-Type Liposarcoma:

(show all 11)
idTitleAuthorsYear
1
Giant mixed-type liposarcoma of the mesentery: case report. (22920010)
2012
2
Oncogenesis and classification of mixed-type liposarcoma: a radiological, histopathological and molecular biological analysis. (20473880)
2011
3
Mediastinal liposarcoma of mixed type in childhood: a report of a case with unusual histologic features. (20699516)
2010
4
Mixed-type liposarcoma: clinicopathological, immunohistochemical, and molecular analysis of a case arising in deep soft tissues of the lower extremity. (18551309)
2008
5
Retroperitoneal mixed-type liposarcoma showing features of four different subtypes. (19097538)
2008
6
Gene expression in mixed type liposarcoma. (16581650)
2006
7
Giant mixed type retroperitoneal liposarcoma. (15305621)
2004
8
Mixed-type liposarcoma of the oral cavity: a case with unusual features and a long survival. (10069544)
1999
9
Case of retroperitoneal dedifferentiated mixed-type liposarcoma: comparison of proliferative activity in specimens from four operations. (10477874)
1999
10
Deletion 6q in three cases of mixed-type liposarcoma in addition to t(12;16)(q13;p11) (7889498)
1995
11
Case report 637. Mixed type liposarcoma with myxoid and pleomorphic patterns. (2255956)
1990

Genetic Variations for Mixed-Type Liposarcoma

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Expression for genes affiliated with Mixed-Type Liposarcoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mixed-Type Liposarcoma

Search GEO for disease gene expression data for Mixed-Type Liposarcoma.

Pathways for genes affiliated with Mixed-Type Liposarcoma

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Sources:
29KEGG, 51QIAGEN, 37NCBI BioSystems Database, 4Cell Signaling Technology, 53Reactome, 52R&D Systems, 12EMD Millipore, 55SinoBiological
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Compounds for genes affiliated with Mixed-Type Liposarcoma

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44Novoseek, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 24HMDB
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Compounds related to Mixed-Type Liposarcoma according to GeneCards/GeneDecks:

(show all 20)
idCompoundScoreTop Affiliating Genes
1fludarabine44 1110.5CDK4, MDM2
2roscovitine449.5CDK4, MDM2
3benzo(a)pyrene449.5MDM2, CDK4
4flavopiridol44 1110.4CDK4, MDM2
5trastuzumab44 49 1111.4CDK4, MDM2
6gefitinib44 49 1111.4CDK4, MDM2
7carboplatin44 49 1111.4CDK4, MDM2
8adpribose449.4CDK4, MDM2
9geldanamycin44 49 59 1112.4MDM2, CDK4
10lactacystin449.4CDK4, MDM2
11sp 60012544 5910.3CDK4, MDM2
12lead449.3MDM2, CDK4
13thymidylate449.3CDK4, MDM2
14resveratrol44 59 11 2412.2MDM2, CDK4
15camptothecin44 59 1111.2CDK4, MDM2
16curcumin449.1CDK4, MDM2
17agar449.1CDK4, MDM2
18valine449.0MDM2, CDK4
195fluorouracil448.8CDK4, MDM2
20zinc44 249.8MDM2, CDK4, FUS

GO Terms for genes affiliated with Mixed-Type Liposarcoma

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16Gene Ontology
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Cellular components related to Mixed-Type Liposarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleolusGO:0057308.5FUS, CDK4, MDM2
2nucleoplasmGO:0056548.2FUS, CDK4, MDM2

Products for genes affiliated with Mixed-Type Liposarcoma

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Sources for Mixed-Type Liposarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet