MCID: MXD031
MIFTS: 24

Mixed-Type Liposarcoma malady

Summaries for Mixed-Type Liposarcoma

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33MalaCards
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MalaCards: Mixed-Type Liposarcoma, also known as mixed liposarcoma, is related to dedifferentiated liposarcoma and myxoid liposarcoma. An important gene associated with Mixed-Type Liposarcoma is FUS (fused in sarcoma), and among its related pathways are Transcriptional misregulation in cancer and Chks in Checkpoint Regulation. The compounds fludarabine and roscovitine have been mentioned in the context of this disorder. Related mouse phenotype reproductive system.

Aliases & Classifications for Mixed-Type Liposarcoma

Sources:
8Disease Ontology, 61UMLS, 40NCIt, 57SNOMED-CT
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Aliases & Descriptions:

mixed-type liposarcoma 8
mixed liposarcoma 8 61


External Ids:

Disease Ontology8 DOID:5709, DOID:5703
SNOMED-CT57 11073003

Related Diseases for Mixed-Type Liposarcoma

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Mixed-Type Liposarcoma:



Diseases related to mixed-type liposarcoma

Clinical Features for Mixed-Type Liposarcoma

Drugs & Therapeutics for Mixed-Type Liposarcoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Mixed-Type Liposarcoma

Drug clinical trials:

Search ClinicalTrials for Mixed-Type Liposarcoma

Search NIH Clinical Center for Mixed-Type Liposarcoma

Search CenterWatch for Mixed-Type Liposarcoma

Genetic Tests for Mixed-Type Liposarcoma

Anatomical Context for Mixed-Type Liposarcoma

Animal Models for Mixed-Type Liposarcoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Mixed-Type Liposarcoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.5FUS, CDK4, MDM2

Publications for Mixed-Type Liposarcoma

Sources:
51PubMed
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Articles related to Mixed-Type Liposarcoma:

(show all 11)
idTitleAuthorsYear
1
Giant mixed-type liposarcoma of the mesentery: case report. (22920010)
2012
2
Oncogenesis and classification of mixed-type liposarcoma: a radiological, histopathological and molecular biological analysis. (20473880)
2011
3
Mediastinal liposarcoma of mixed type in childhood: a report of a case with unusual histologic features. (20699516)
2010
4
Mixed-type liposarcoma: clinicopathological, immunohistochemical, and molecular analysis of a case arising in deep soft tissues of the lower extremity. (18551309)
2008
5
Retroperitoneal mixed-type liposarcoma showing features of four different subtypes. (19097538)
2008
6
Gene expression in mixed type liposarcoma. (16581650)
2006
7
Giant mixed type retroperitoneal liposarcoma. (15305621)
2004
8
Mixed-type liposarcoma of the oral cavity: a case with unusual features and a long survival. (10069544)
1999
9
Case of retroperitoneal dedifferentiated mixed-type liposarcoma: comparison of proliferative activity in specimens from four operations. (10477874)
1999
10
Deletion 6q in three cases of mixed-type liposarcoma in addition to t(12;16)(q13;p11) (7889498)
1995
11
Case report 637. Mixed type liposarcoma with myxoid and pleomorphic patterns. (2255956)
1990

Genetic Variations for Mixed-Type Liposarcoma

Expression for genes affiliated with Mixed-Type Liposarcoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mixed-Type Liposarcoma

Search GEO for disease gene expression data for Mixed-Type Liposarcoma.

Pathways for genes affiliated with Mixed-Type Liposarcoma

Sources:
30KEGG, 52QIAGEN, 38NCBI BioSystems Database, 4Cell Signaling Technology, 54Reactome, 53R&D Systems, 12EMD Millipore, 56SinoBiological
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Compounds for genes affiliated with Mixed-Type Liposarcoma

Sources:
45Novoseek, 11DrugBank, 50PharmGKB, 60Tocris Bioscience, 24HMDB
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Compounds related to Mixed-Type Liposarcoma according to GeneCards/GeneDecks:

(show all 20)
idCompoundScoreTop Affiliating Genes
1fludarabine45 1110.5CDK4, MDM2
2roscovitine459.5CDK4, MDM2
3benzo(a)pyrene459.5MDM2, CDK4
4flavopiridol45 1110.4CDK4, MDM2
5trastuzumab45 50 1111.4CDK4, MDM2
6gefitinib45 50 1111.4CDK4, MDM2
7carboplatin45 50 1111.4CDK4, MDM2
8adpribose459.4CDK4, MDM2
9geldanamycin45 50 60 1112.4MDM2, CDK4
10lactacystin459.4CDK4, MDM2
11sp 60012545 6010.3CDK4, MDM2
12lead459.3MDM2, CDK4
13thymidylate459.3CDK4, MDM2
14resveratrol45 60 11 2412.2MDM2, CDK4
15camptothecin45 60 1111.2CDK4, MDM2
16curcumin459.1CDK4, MDM2
17agar459.1CDK4, MDM2
18valine459.0MDM2, CDK4
195fluorouracil458.8CDK4, MDM2
20zinc45 249.8MDM2, CDK4, FUS

GO Terms for genes affiliated with Mixed-Type Liposarcoma

Sources:
16Gene Ontology
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Cellular components related to Mixed-Type Liposarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleolusGO:0057308.5FUS, CDK4, MDM2
2nucleoplasmGO:0056548.2FUS, CDK4, MDM2

Products for genes affiliated with Mixed-Type Liposarcoma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mixed-Type Liposarcoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet