MCID: MDR006
MIFTS: 23

Moderate and Severe Traumatic Brain Injury malady

Rare diseases, Neuronal diseases categories

Aliases & Classifications for Moderate and Severe Traumatic Brain Injury

About this section
Sources:
47Orphanet, 26ICD10 via Orphanet
See all sources

Summaries for Moderate and Severe Traumatic Brain Injury

About this section


MalaCards based summary: Moderate and Severe Traumatic Brain Injury is related to brain injury and traumatic brain injury. An important gene associated with Moderate and Severe Traumatic Brain Injury is APOE (apolipoprotein E), and among its related pathways is A-beta Uptake and Degradation. The compounds sele and atenolol have been mentioned in the context of this disorder. Affiliated tissues include brain, and related mouse phenotypes are renal/urinary system and adipose tissue.

Related Diseases for Moderate and Severe Traumatic Brain Injury

About this section

Graphical network of diseases related to Moderate and Severe Traumatic Brain Injury:



Diseases related to moderate and severe traumatic brain injury

Symptoms for Moderate and Severe Traumatic Brain Injury

About this section

Drugs & Therapeutics for Moderate and Severe Traumatic Brain Injury

About this section

Drug clinical trials:

Search ClinicalTrials for Moderate and Severe Traumatic Brain Injury

Search NIH Clinical Center for Moderate and Severe Traumatic Brain Injury

Genetic Tests for Moderate and Severe Traumatic Brain Injury

About this section

Anatomical Context for Moderate and Severe Traumatic Brain Injury

About this section

MalaCards organs/tissues related to Moderate and Severe Traumatic Brain Injury:

31
Brain

Animal Models for Moderate and Severe Traumatic Brain Injury or affiliated genes

About this section

MGI Mouse Phenotypes related to Moderate and Severe Traumatic Brain Injury:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053679.1ACE, APOE
2MP:00053759.0ACE, APOE
3MP:00053708.8ACE, APOE

Publications for Moderate and Severe Traumatic Brain Injury

About this section

Articles related to Moderate and Severe Traumatic Brain Injury:

idTitleAuthorsYear
1
Hypocalcaemia as a prognostic factor of early mortality in moderate and severe traumatic brain injury. (24139087)
2014
2
Impact of rehabilitation on functional outcome during the first year of moderate and severe traumatic brain injury. (24378157)
2013
3
Prediction of outcome after moderate and severe traumatic brain injury: external validation of the International Mission on Prognosis and Analysis of Clinical Trials (IMPACT) and Corticoid Randomisation After Significant Head injury (CRASH) prognostic models. (22511138)
2012
4
Influence of APOE polymorphism on cognitive and behavioural outcome in moderate and severe traumatic brain injury. (16614010)
2006
5
Influence of Angiotensin-converting enzyme polymorphism on neuropsychological subacute performance in moderate and severe traumatic brain injury. (16525069)
2006

Variations for Moderate and Severe Traumatic Brain Injury

About this section

Expression for genes affiliated with Moderate and Severe Traumatic Brain Injury

About this section
Search GEO for disease gene expression data for Moderate and Severe Traumatic Brain Injury.

Pathways for genes affiliated with Moderate and Severe Traumatic Brain Injury

About this section

Pathways related to Moderate and Severe Traumatic Brain Injury according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1ACE, APOE

Compounds for genes affiliated with Moderate and Severe Traumatic Brain Injury

About this section
Sources:
43Novoseek, 49PharmGKB, 28IUPHAR, 24HMDB, 12DrugBank
See all sources

Compounds related to Moderate and Severe Traumatic Brain Injury according to GeneCards Suite gene sharing:

(show all 12)
idCompoundScoreTop Affiliating Genes
1sele439.4ACE, APOE
2atenolol43 49 28 24 1213.4ACE, APOE
3warfarin43 49 24 1212.4ACE, APOE
4fluvastatin43 49 28 1212.3APOE, ACE
5losartan43 49 28 1212.3ACE, APOE
6pravastatin43 49 28 24 1213.3ACE, APOE
7atorvastatin43 49 28 24 1213.2APOE, ACE
8prostacyclin439.2ACE, APOE
9aspirin43 49 28 2412.1ACE, APOE
10cholesterol43 28 24 1212.1ACE, APOE
11acetylcholine43 49 28 24 1213.0APOE, ACE
12creatinine438.8ACE, APOE

GO Terms for genes affiliated with Moderate and Severe Traumatic Brain Injury

About this section

Cellular components related to Moderate and Severe Traumatic Brain Injury according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056159.1ACE, APOE

Products for genes affiliated with Moderate and Severe Traumatic Brain Injury

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Moderate and Severe Traumatic Brain Injury

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet