MCID: MLL001
MIFTS: 44

Molluscum Contagiosum malady

Infectious diseases, Neuronal diseases, Skin diseases, Mental diseases categories

Summaries for Molluscum Contagiosum

About this section


Disease Ontology:9 A viral infectious disease that results in infection located in skin, has material basis in molluscum contagiosum virus, which is transmitted by contact with the skin, and transmitted by fomites. the infection has symptom lesions which are flesh-colored with a pit in the center.

MalaCards based summary: Molluscum Contagiosum is related to atopic dermatitis and dermatitis, and has symptoms including lesions which are flesh-colored An important gene associated with Molluscum Contagiosum is LOR (loricrin), and among its related pathways are Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways and Legionellosis. The drug cantharidin and the compounds hematoxylin and infliximab have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and t cells, and related mouse phenotypes are integument and hematopoietic system.

Wikipedia:63 Molluscum contagiosum (MC) is a viral infection of the skin or occasionally of the mucous membranes,... more...

Aliases & Classifications for Molluscum Contagiosum

About this section
Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 3CDC, 60UMLS, 33MeSH, 27ICD9CM, 55SNOMED-CT, 25ICD10
See all sources

Related Diseases for Molluscum Contagiosum

About this section

Graphical network of the top 20 diseases related to Molluscum Contagiosum:



Diseases related to molluscum contagiosum

Symptoms for Molluscum Contagiosum

About this section

Symptoms:

 9
  • lesions which are flesh-colored

Drugs & Therapeutics for Molluscum Contagiosum

About this section

Drug clinical trials:

Search ClinicalTrials for Molluscum Contagiosum

Search NIH Clinical Center for Molluscum Contagiosum

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Molluscum Contagiosum

About this section

Anatomical Context for Molluscum Contagiosum

About this section

MalaCards organs/tissues related to Molluscum Contagiosum:

31
Skin, T cells, Cervix, Bone marrow, Bone, Lung, Myeloid, B cells

FMA organs/tissues related to Molluscum Contagiosum:

14
Skin

Animal Models for Molluscum Contagiosum or affiliated genes

About this section

MGI Mouse Phenotypes related to Molluscum Contagiosum:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.4LOR, CASP8, IL18, FLG
2MP:00053978.4CASP8, IL11RA, IL18, FLG
3MP:00053878.0CASP8, FLG, LOR, IL18, IL11RA
4MP:00053787.9FLG, LOR, IL11RA, CASP8, IL18
5MP:00107687.2CASP8, FLG, TOP1, IL18, IL11RA

Publications for Molluscum Contagiosum

About this section

Articles related to Molluscum Contagiosum:

(show top 50)    (show all 528)
idTitleAuthorsYear
1
Eruptive xanthomas masquerading as molluscum contagiosum. (24918225)
2014
2
Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum. (24559566)
2014
3
Treatment of molluscum contagiosum in adult, pediatric, and immunodeficient populations. (25186990)
2014
4
Potassium hydroxide 5% for the treatment of molluscum contagiosum. (25298120)
2014
5
Molluscum contagiosum infection on a congenital intermediate melanocytic naevus. (25183021)
2014
6
Idiopathic CD4 lymphocytopenia presenting as recurrent giant molluscum contagiosum. (23760345)
2013
7
Unusual manifestation of molluscum contagiosum: eruptive papules on the face and neck of an immunocompetent patient. (24003298)
2013
8
Gross generalized molluscum contagiosum in a patient with autosomal recessive hyper-IgE syndrome, which resolved spontaneously after haematopoietic stem-cell transplantation. (23020750)
2013
9
An open, comparative study of 10% potassium hydroxide solution versus salicylic and lactic acid combination in the treatment of molluscum contagiosum in children. (22214282)
2013
10
Detection of molluscum contagiosum virus (MCV) DNA in the plasma of an immunocompromised patient and possible reduction of MCV DNA with CMX-001. (22262788)
2012
11
Molluscum contagiosum as a skin manifestation of immune reconstitution inflammatory syndrome in an AIDS patient who is receiving HAART. (22787541)
2012
12
Dermoscopic patterns of molluscum contagiosum: a study of 211 lesions confirmed by histopathology. (21437525)
2011
13
What is your diagnosis? Molluscum contagiosum on the sole of the foot. (21644487)
2011
14
Recalcitrant giant molluscum contagiosum in a patient with advanced HIV disease - eradication of disease with paclitaxel. (21245518)
2010
15
An immunocompromised woman with severe molluscum contagiosum that responded well to topical imiquimod: a case report and literature review. (20354423)
2010
16
Molluscum contagiosum: A 20-year study in a sexually transmitted infections unit. (20414149)
2010
17
Treatment of facial molluscum contagiosum with trichloroacetic acid. (19689517)
2009
18
Molluscum contagiosum and dental caries: a pertinent combination. (19915268)
2009
19
Resolution of giant Molluscum contagiosum with antiretroviral therapy. (18583804)
2008
20
Medical Pearl: confirming the diagnosis of molluscum contagiosum using 10% potassium hydroxide. (17434028)
2007
21
Detection of Molluscum contagiosum virus (MCV) subtype I as a single dominant virus subtype in Molluscum lesions from a Turkish population. (16513490)
2006
22
Topical treatment of molluscum contagiosum with imiquimod 5% cream in Turkish children. (16911087)
2006
23
Molluscum contagiosum infection during the treatment of vitiligo with tacrolimus ointment. (15761441)
2005
24
Treatment of molluscum contagiosum with 585 nm collagen remodeling pulsed dye laser. (15197000)
2004
25
Molluscum contagiosum-like lesions in lepromatous leprosy. (15267197)
2003
26
Photodynamic therapy for molluscum contagiosum infection in HIV-coinfected patients: review of 6 patients. (14711142)
2003
27
Molluscum contagiosum. (12639455)
2003
28
Clinical profile of molluscum contagiosum in children versus adults. (14996374)
2003
29
Molluscum contagiosum: recent advances in pathogenic mechanisms, and new therapies. (12358555)
2002
30
MC148 encoded by human molluscum contagiosum poxvirus is an antagonist for human but not murine CCR8. (11493620)
2001
31
Efficacy of emlap cream in children having molluscum contagiosum. (17664726)
2001
32
Molluscum contagiosum virus expresses late genes in primary human fibroblasts but does not produce infectious progeny. (11210936)
2001
33
Treatment of molluscum contagiosum with topical 5% imiquimod cream. (11085678)
2000
34
Pleomorphic T-cell infiltrate associated with molluscum contagiosum. (10218681)
1999
35
Characterization of early gene transcripts of molluscum contagiosum virus. (10208926)
1999
36
DNA contacts by protein domains of the molluscum contagiosum virus type-1B topoisomerase. (10502526)
1999
37
Molluscum contagiosum. (9891691)
1998
38
Recalcitrant molluscum contagiosum in a patient with AIDS successfully treated by a combination of CO2-laser and natural interferon beta gel. (9689311)
1998
39
Molluscum contagiosum eyelid lesions as the initial manifestation of acquired immunodeficiency syndrome. (9262550)
1997
40
Failure to detect human papilloma virus in cutaneous molluscum contagiosum lesions. (9494606)
1997
41
Strategy for identifying the gene encoding the DNA polymerase of molluscum contagiosum virus type 1. (8938977)
1996
42
Expression of keratohyalin-trichohyalin hybrid granules in molluscum contagiosum. (8850037)
1996
43
Replication of molluscum contagiosum virus. (7491789)
1995
44
Identification and properties of the genes encoding the poly(A) polymerase and a small (22 kDa) and the largest subunit (147 kDa) of the DNA-dependent RNA polymerase of molluscum contagiosum virus. (7618282)
1995
45
Molluscum contagiosum. (7928025)
1994
46
Facial and perioral molluscum contagiosum in patients with HIV infection. A report of eight cases. (7838470)
1994
47
Cutaneous cryptococcosis resembling molluscum contagiosum in a homosexual man with AIDS. Report of a case and review of the literature. (1357854)
1992
48
Molluscum contagiosum in HIV-infected patients. (1558989)
1992
49
Giant molluscum contagiosum following splenectomy. (2383191)
1990
50
Treatment of molluscum contagiosum using a lidocaine/prilocaine cream (EMLA) for analgesia. (2229496)
1990

Variations for Molluscum Contagiosum

About this section

Expression for genes affiliated with Molluscum Contagiosum

About this section
Search GEO for disease gene expression data for Molluscum Contagiosum.

Pathways for genes affiliated with Molluscum Contagiosum

About this section

Compounds for genes affiliated with Molluscum Contagiosum

About this section

Compounds related to Molluscum Contagiosum according to GeneCards Suite gene sharing:

(show all 43)
idCompoundScoreTop Affiliating Genes
1hematoxylin4310.0LOR, FLG
2infliximab43 49 1211.9FLG, IL18
3allergens439.8IL18, FLG
4latex439.8IL18, FLG
5mevalonate439.7IL18, CASP8
6ifn-alpha439.7CASP8, IL18
7pdtc439.6IL18, CASP8
8tetracycline43 1210.6IL18, CASP8
9sp 60012543 5910.6IL18, CASP8
10ciprofloxacin43 49 1211.5TOP1, IL18
114,6-diamidino-2-phenylindole439.5TOP1, CASP8
12ursolic acid439.5CASP8, TOP1
13shikonin439.5TOP1, CASP8
14betulinic acid43 2810.4CASP8, TOP1
15tgf beta1439.4IL18, CASP8
16topotecan43 1210.4CASP8, TOP1
17depsipeptide439.4TOP1, CASP8
18oxaliplatin43 49 1211.4CASP8, TOP1
19simvastatin43 49 59 28 24 1214.4CASP8, IL18
20flavopiridol43 1210.4CASP8, TOP1
21melphalan43 49 1211.4TOP1, CASP8
22steroid439.4FLG, IL18, LOR
23daunorubicin43 49 1211.4TOP1, CASP8
24bortezomib43 49 1211.4CASP8, TOP1
25adpribose439.3CASP8, TOP1
26gemcitabine43 49 1211.3TOP1, CASP8
27curcumin439.2CASP8, IL18
28adriamycin439.2CASP8, TOP1
29camptothecin43 59 1211.2CASP8, TOP1
30docetaxel43 49 59 1212.2CASP8, TOP1
31cyclophosphamide43 49 1211.1IL18, TOP1
32arginine439.1IL18, FLG, CASP8
33mitomycin c438.9TOP1, CASP8, IL18
34egcg438.9TOP1, IL18, CASP8
355fluorouracil438.9CASP8, TOP1, IL18
36doxorubicin43 49 1210.9CASP8, IL18, TOP1
37cisplatin43 49 59 1211.9TOP1, IL18, CASP8
38retinoic acid43 249.9CASP8, FLG, LOR, IL18
39cysteine438.9IL18, FLG, CASP8
40cycloheximide438.9CASP8, TOP1, IL18
41serine438.9IL18, LOR, CASP8, FLG
42h2o2438.8TOP1, IL18, CASP8
435-aza-2deoxycytidine438.7CASP8, TOP1

GO Terms for genes affiliated with Molluscum Contagiosum

About this section

Biological processes related to Molluscum Contagiosum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratinocyte differentiationGO:00302169.6LOR, FLG
2natural killer cell activationGO:00301019.2CASP8, IL18
3cellular response to organic cyclic compoundGO:00714079.0CASP8, IL18

Products for genes affiliated with Molluscum Contagiosum

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Molluscum Contagiosum

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet