MCID: MLL001
MIFTS: 45

Molluscum Contagiosum malady

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Molluscum Contagiosum

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Summaries for Molluscum Contagiosum

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Disease Ontology:10 A viral infectious disease that results in infection located in skin, has material basis in Molluscum contagiosum virus, which is transmitted by contact with the skin, and transmitted by fomites. The infection has symptom lesions which are flesh-colored with a pit in the center.

MalaCards based summary: Molluscum Contagiosum is related to orofaciodigital syndrome iv and contact dermatitis, and has symptoms including lesions which are flesh-colored An important gene associated with Molluscum Contagiosum is CASP8 (Caspase 8), and among its related pathways are Legionellosis and A-beta Signaling Pathways. The drug cantharidin has been mentioned in the context of this disorder. Affiliated tissues include skin, skin and breast, and related mouse phenotype immune system.

Wikipedia:68 Molluscum contagiosum (MC) is a viral infection of the skin or occasionally of the mucous membranes,... more...

Related Diseases for Molluscum Contagiosum

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Diseases related to Molluscum Contagiosum via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1orofaciodigital syndrome iv9.9CASP8, FADD
2contact dermatitis9.8FLG, LOR
3ichthyosis vulgaris9.7FLG, LOR
4palmoplantar keratoderma, epidermolytic9.7FLG, LOR
5epidural spinal canal meningioma9.6FLG, LOR
6ichthyosis, cyclic, with epidermolytic hyperkeratosis9.5FLG, LOR
7penis carcinoma in situ7.9CASP8, CCR8, CORO1A, CXCL12, FADD, FLG

Graphical network of diseases related to Molluscum Contagiosum:



Diseases related to molluscum contagiosum

Symptoms for Molluscum Contagiosum

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Symptoms:

 10
  • lesions which are flesh-colored

Drugs & Therapeutics for Molluscum Contagiosum

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Drugs for Molluscum Contagiosum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Pharmaceutical SolutionsPhase 2, Phase 37004
2CantharidinPhase 28
3
Benzocaineapproved16841994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
20/20 Topical Anesthetic
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Alcohol Prep Pads
Allegenal-m
Alpha-caine Topical Anesthetic
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anbesol Jr
Anbesol Maximum Strength
Anbesol Regular Strength
Anestenka
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthetic
Anesthone
Atopalm Oral Pain Relief
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Baby Anestenka
Baby Sensigel
Baby Sensigel Night Time Formula
Baby Teething Oral Pain Reliever
Bactimicina For Sore Throat
Bencocaine Topical Anesthetic
Bensokain
Benz O Sthetic
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzodent
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
Boil Ease
Boy Butter Desensitizing Lubricant
Boy Butter Extreme Desensitizing Lubricant
Boy Butter Extreme H2O Desensitizing Lubricant
Brace Relief
Budpak Baby Teething Oral Pain Reliever
Budpak Oral Maximum Strength
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Carmex Cold Sore Treatment External Analgesic
Caswell No. 430A
Cepacol Fizzlers
Cepacol Sensations Hydra
Cepacol Sensations Sore Throat Hydra citrus splash
Cepacol Sensations Warming
Certus Sting Relief Prep Pad
Chloraseptic
Chloraseptic Warming Sore Throat
Colgate Orabase
Comfortcaine Topical Anesthetic
Cvs Fast Acting Baby Teething
Cvs Maximum Strength
Cvs Maximum Strength Boil Relief
Cvs Oral Anesthetic
Cvs Pharmacy Instant Toothache
Cvs Pharmacy Maximum Strength
Cvs Pharmacy Mouth Sore Gel
Cvs Pharmacy Nighttime Oral Pain Relief
D001566
D00552
DB01086
Dental Relief
Dentek Instant Pain Relief Maximum Strength
Dermoplast
Diet Ayds
DivK1c_000932
Dollar General Toothache Relief
Dukal Sting Relief Pad
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Finafta Baby
Finafta MultiOral
Formate, Benzocaine
Gelato Topical Anesthetic
Good Neighbor Pain Relief
Goodsense Oral Pain Relief
Gps Topical Anesthetic
Gumnumb Topical Anesthetic
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Heb Severe Toothache
Herbasoul Male Genital Desensitizer Cream
 
Hurricaine
Hurricaine Topical Anesthetic
Hurricaine Topical Anesthetic Gel
Hurricaine Topical Anesthetic Liquid
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
Insect Bite Relief
Instant Toothache Pain Relief
Intense Cvs Intense Toothache
Iodent Maximum Strength Oral Analgesic
Ismile Topical Anesthetic
Jianze Sting Relief Pads
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Kank-a Mouth Pain
Keloform
Kmart Smart Sense
Kroger Toothache Pain Relief
LS-35847
Leader Oral Analgesic
Little Colds Sore Throat Relief Melt Aways
MLS001331704
MLS002153970
Makesense Junior Pain Relief
Makesense Pain Relief
Male Desensitizer Pleasure Balm
Mandelay Male Genital Desensitizer
Mark 3
Methanesulfonate, Benzocaine
MolPort-000-871-526
Mouth Sore Medication
Mouth Sore Relief Applicator
Mouth Sore Relief Professional Strength
My Fair Baby Instant Pain Relief
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Nene Dente
Norcain
Norcaine
Norcainum
Opahl
Opahl Dye Free
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orajel For All Mouth Sores Maximum Strength
Orajel For Cold Sores
Orajel For Toothache Maximum Strength
Orajel Instant Pain Relief Maximum Strength
Orajel Instant Pain Relief Regular Strength
Orajel Instant Relief For Teething Pain
Orajel Instant Relief For Teething Pain Cooling Cucumber
Orajel Instant Relief For Teething Pain Daytime Nighttime Twin Pack
Orajel Instant Relief For Teething Pain Longer Lasting
Orajel Maximum Strength
Orajel Nighttime Instant Relief For Teething Pain Longer Lasting Extra Strength
Orajel Severe Toothache Maximum Strength Fast-Acting Formula
Oral Analgesic Maximum Strength
Oral B Instant Pain Relief
Oral Gel Maximum Strength
Oral Pain Relief Anesthetic Anesthetic
Oral Pain Reliever
Oralabs Cold Sore Treatment
Orthesin
Otocain
Outgro
Pac-dent Top Gel
Pain Relief
Pain Relief Alcohol Swabs
Parathesin
Parathesin (TN)
Parathesine
Physicians Care Sting Relief Pad
Pleasure Balm Kama Sutra
Preboost
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
Purelife Topical Anesthetic
Quality Choice Maximum Strength Oral Pain Relieving
Red Cross Oral Pain Relief
Rexall Maximum Strength
Rite Aid Baby Care
Rite Aid Liquid Anesthetic Oral Pain Relief
Rite Aid Maximum Strength
Rite Aid Oral Pain Reliever
Rite Aid Professional Strength
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Sally Hansen Ouch-relief Numbing Wipes
Sally Hansen Ouch-relief Wax Kit
Sally Hansen Ouch-relief Wax Strip Kit
Sensigel
Severe Oral Pain Reliever
Sheffield Baby Teething Gel
Sheffield Pain Relief
Shunga Male Genital Desensitizer
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Sting Relief Medicated Pad
Sting Relief Pads
Tanac
Terrasil Boil Pain Relief
Tiger Supply Inc Topical Anesthetic
Top Quality Mfg. Topical Anesthetic
Topcaine
Topcare Maximum Strength
Topical Anesthetic Banana
Topical Anesthetic Bubble Gum
Topical Anesthetic Cherry
Topical Anesthetic Mint
Topical Anesthetic Pina Colada
Topical Anesthetic Raspberry
Topical Anesthetic Strawberry
UNII-U3RSY48JW5
Ultracare Anesthetic Bubble Gum
Ultracare Anesthetic Butter Rum
Ultracare Anesthetic Creme de Menthe
Ultracare Anesthetic Pina Colada
Ultracare Anesthetic Walterberry
WLN: ZR DVO2
Walgreens Baby Teething
Walgreens Intense Toothache
Walgreens Maximum Strength
Walgreens Pain Relieving For Boils
Walgreens Severe Oral Pain Reliever
Walgreens Severe Toothache Relief
Winco Foods Maximum Strength Oral Analgesic
ZINC12358719
Zilactin-b
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
4tannic acidNutraceutical1684

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy and Tolerance of Potassium Hydroxide (10% and 15%) in Molluscum ContagiosumCompletedNCT01348386Phase 2, Phase 3
2Safety and Efficacy Study of Topical Cantharidin for the Treatment of Molluscum ContagiosumCompletedNCT02665260Phase 2
3A Dose Range-Finding Phase 2 Trial of a Botanical Drug for the Treatment of Molluscum Contagiosum in Pediatric SubjectsRecruitingNCT02024581Phase 2
4Efficacy of Cantharidin in Molluscum ContagiosumCompletedNCT00667225

Search NIH Clinical Center for Molluscum Contagiosum

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: molluscum contagiosum

Genetic Tests for Molluscum Contagiosum

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Anatomical Context for Molluscum Contagiosum

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MalaCards organs/tissues related to Molluscum Contagiosum:

33
Skin, Breast, Lung, Heart, Endothelial, T cells, Brain

FMA organs/tissues related to Molluscum Contagiosum:

16
Skin

Animal Models for Molluscum Contagiosum or affiliated genes

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MGI Mouse Phenotypes related to Molluscum Contagiosum:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.8CASP8, CCR8, CORO1A, CXCL12, FADD, TLR2

Publications for Molluscum Contagiosum

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Articles related to Molluscum Contagiosum:

(show top 50)    (show all 548)
idTitleAuthorsYear
1
Choroidal Neovascularization Secondary to Myopia, Infection and Inflammation. (26501802)
2016
2
Two novel mutations of the SETX gene and ataxia with oculomotor apraxia type 2. (25462094)
2015
3
Chest CT Findings in EBUS-TBNA-Proven Anthracosis inA Enlarged Mediastinal Lymph Nodes. (24955645)
2014
4
Chromosome 18q deletion syndrome with autoimmune diabetes mellitus: putative genomic loci for autoimmunity and immunodeficiency. (25403779)
2014
5
Fetal alcohol syndrome (FAS) and fetal alcohol spectrum disorder (FASD)-diagnosis and moral policing; an ethical dilemma for paediatricians. (25005521)
2014
6
Evaluation of antibody response of killed and live vaccines against porcine epidemic diarrhea virus in a field study. (25398090)
2014
7
Impact of delayed implant and DIEP flap breast reconstruction on body image and sexual satisfaction: a prospective follow-up study. (23983109)
2014
8
Alteration of plasma phospholipid fatty acid profile in patients with septic shock. (23954620)
2013
9
Comparison of mometasone furoate monohydrate (Nasonex) and fluticasone propionate (Flixonase) nasal sprays in the treatment of dust mite-sensitive children with perennial allergic rhinitis. (23597528)
2013
10
"IDSA/ATS minor criteria aided pre-ICU resuscitation in severe community-acquired pneumonia" (24176994)
2013
11
PON1 Q192R genotype influences clopidogrel responsiveness by relative platelet inhibition instead of on-treatment platelet reactivity. (23993903)
2013
12
Functional genetic variations in the IL-23 receptor gene are associated with risk of breast, lung and nasopharyngeal cancer in Chinese populations. (23042301)
2012
13
Should we resect all multiple intraspinal extradural arachnoid cysts? A case report. (22843467)
2012
14
Phenotypic and genotypic variability in Alpers syndrome. (22237560)
2012
15
Regulation of NR4A nuclear receptor expression by oncogenic BRAF in melanoma cells. (21362156)
2011
16
Influence of class M1 glutathione S-transferase (GST Mu) polymorphism on GST M1 gene expression level and tumor size in oral squamous cell carcinoma. (20060357)
2010
17
Secreted frizzled-related protein 1 (SFRP1) is highly upregulated in keratoconus epithelium: a novel finding highlighting a new potential focus for keratoconus research and treatment. (20447100)
2010
18
Plasma calprotectin in chronically dialyzed end-stage renal disease patients. (19856199)
2010
19
Serotonin and dopamine transporter genes do not influence depression in Parkinson's disease. (18973248)
2009
20
A variant form of autoimmune pancreatitis successfully treated by steroid therapy, accompanied by von Meyenburg complex. (19195067)
2009
21
Crystal structure of human synbindin reveals two conformations of longin domain. (18466758)
2009
22
Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice. (19520794)
2009
23
Activation of keratinocyte protein kinase C zeta in psoriasis plaques. (18385757)
2008
24
The phenomenology and diagnosis of psychiatric illness in people with Prader-Willi syndrome. (18177526)
2008
25
Hepatocyte growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells. (17464449)
2007
26
Multiple substance dependence and course of alcoholism among Alaska native men and women. (16603457)
2006
27
Aniridia (PAX6(+/-)). (15825752)
2005
28
NKG2D-independent suppression of T cell proliferation by H60 and MICA. (16091471)
2005
29
Reevaluation of myoglobin for acute chest pain evaluation: would false-positive results on "first-draw" specimens lead to increased hospital admissions? (15198351)
2004
30
Chemotherapy-induced, age-related changes in antischistosome antibody responses. (12791104)
2003
31
Clinical and radiologic characteristics of the imploding antrum, or "silent sinus," syndrome. (12689908)
2003
32
Coexistence of aneurysmal subarachnoid haemorrhage and pituitary apoplexy: Case report and review of the literature. (12852891)
2003
33
Extensive retroperitoneal fibrosis with duodenal and ureteral obstruction associated with giant inflammatory aneurysm of the abdominal aorta. (14677743)
2003
34
Rotation osteotomy of the humerus for Erb's palsy in children with humeral head deformity. (12015723)
2002
35
Tc-99m hexamethylpropylene amine oxime leukocyte pinhole imaging of the scrotum in patients with epididymitis showing equivocal clinical and scintigraphic findings. (11595860)
2001
36
Differential MAPK pathways utilized for HGF- and EGF-dependent renal epithelial morphogenesis. (11118451)
2001
37
Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization. (10899121)
2000
38
Serum transferrin and serum prealbumin are early predictors of serum albumin in chronic hemodialysis patients. (11070145)
2000
39
Mutation screening in Rett syndrome patients. (10745042)
2000
40
Altered brain metabolism in the C57BL/Wld mouse strain detected by magnetic resonance spectroscopy: association with delayed Wallerian degeneration? (10500267)
1999
41
Primary pulmonary hypertension: pathologist as patient. (9670148)
1998
42
Immunohistochemical localization of MUC 1 and keratin 14 in the invasive regions of malignant eyelid tumors]. (9396233)
1997
43
Psychogenic (reactive) and hysterical psychoses: a cross-system reliability study. (9065675)
1997
44
Calcium retention estimated from indicators of skeletal status in adolescent girls and young women. (8669416)
1996
45
Trandolapril in patients with left ventricular insufficiency after myocardial infarction]. (8949315)
1996
46
Clinical and economic lessons from studies of coronary thrombolysis. (8770850)
1995
47
Seizures-in-series observed in symptomatic generalized epilepsy other than West syndrome. (8612183)
1995
48
Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis. (8147551)
1994
49
Angiotensin II enhances insulin sensitivity in healthy volunteers under euglycemic conditions. (8254181)
1993
50
Value of steroid hormone receptors as prognostic factors in breast, ovarian and endometrial cancer]. (8508979)
1993

Variations for Molluscum Contagiosum

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Expression for genes affiliated with Molluscum Contagiosum

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Search GEO for disease gene expression data for Molluscum Contagiosum.

Pathways for genes affiliated with Molluscum Contagiosum

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GO Terms for genes affiliated with Molluscum Contagiosum

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Biological processes related to Molluscum Contagiosum according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1death-inducing signaling complex assemblyGO:007155010.0CASP8, FADD
2positive regulation of macrophage differentiationGO:004565110.0CASP8, FADD
3toll-like receptor 4 signaling pathwayGO:003414210.0CASP8, TLR2
4negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:19020429.8CASP8, FADD
5regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:19020419.8CASP8, FADD
6regulation of necrotic cell deathGO:00109399.8CASP8, FADD
7T cell homeostasisGO:00430299.7CORO1A, FADD
8activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayGO:00972969.7CASP8, FADD
9extrinsic apoptotic signaling pathwayGO:00971919.7CASP8, FADD
10positive regulation of proteolysisGO:00458629.6CASP8, FADD
11cellular response to mechanical stimulusGO:00712609.5CASP8, FADD
12TRIF-dependent toll-like receptor signaling pathwayGO:00356669.5CASP8, FADD
13activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.4CASP8, FADD
14negative regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:00431549.2CASP8, FADD
15toll-like receptor signaling pathwayGO:00022249.2CASP8, FADD, TLR2

Sources for Molluscum Contagiosum

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet