MCID: MLL001
MIFTS: 31

Molluscum Contagiosum

Categories: Infectious diseases

Aliases & Classifications for Molluscum Contagiosum

Summaries for Molluscum Contagiosum

CDC : 3 Molluscum contagiosum is an infection caused by a poxvirus (molluscum contagiosum virus). The result of the infection is usually a benign, mild skin disease characterized by lesions (growths) that may appear anywhere on the body. Within 6-12 months, Molluscum contagiosum typically resolves without scarring but may take as long as 4 years.

MalaCards based summary : Molluscum Contagiosum is related to hyper-ige recurrent infection syndrome, autosomal recessive and benta disease. An important gene associated with Molluscum Contagiosum is FLG (Filaggrin). The drugs Pharmaceutical Solutions and Cantharidin have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and cervix.

Disease Ontology : 12 A viral infectious disease that results_in infection located in skin, has material basis in Molluscum contagiosum virus, which is transmitted_by contact with the skin, and transmitted_by fomites. The infection has symptom lesions which are flesh-colored with a pit in the center.

Wikipedia : 72 Molluscum contagiosum (MC), sometimes called water warts, is a viral infection of the skin that results... more...

Related Diseases for Molluscum Contagiosum

Diseases related to Molluscum Contagiosum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 83)
id Related Disease Score Top Affiliating Genes
1 hyper-ige recurrent infection syndrome, autosomal recessive 11.1
2 benta disease 11.1
3 dermatitis 10.2
4 leprosy 10.2
5 atopic dermatitis 10.2
6 cryptococcosis 10.2
7 acquired immunodeficiency syndrome 10.2
8 herpes simplex 10.2
9 lymphoma 10.1
10 lepromatous leprosy 10.1
11 epidermodysplasia verruciformis 10.0
12 basal cell carcinoma 10.0
13 histiocytosis 10.0
14 cellulitis 10.0
15 psoriasis 10.0
16 hyper ige syndrome 10.0
17 cutaneous pseudolymphoma 10.0
18 hiv-1 9.9
19 burns 9.9
20 erythema multiforme 9.9
21 methemoglobinemia 9.9
22 sarcoma 9.9
23 histoplasmosis 9.9
24 squamous cell carcinoma 9.9
25 papilloma 9.9
26 vaccinia 9.9
27 folliculitis 9.9
28 scabies 9.9
29 herpes zoster 9.9
30 rheumatoid arthritis 9.8
31 asthma 9.8
32 kaposi sarcoma 9.8
33 multiple myeloma 9.8
34 retinoblastoma 9.8
35 wiskott-aldrich syndrome 9.8
36 mycosis fungoides 9.8
37 acne 9.8
38 arthritis 9.8
39 b-cell lymphomas 9.8
40 crohn's disease 9.8
41 granuloma annulare 9.8
42 hepatitis 9.8
43 hepatitis b 9.8
44 leukemia 9.8
45 skin conditions 9.8
46 tinea barbae 9.8
47 cutaneous lupus erythematosus 9.8
48 exanthem 9.8
49 fibroma 9.8
50 tuberculoid leprosy 9.8

Graphical network of the top 20 diseases related to Molluscum Contagiosum:



Diseases related to Molluscum Contagiosum

Symptoms & Phenotypes for Molluscum Contagiosum

Drugs & Therapeutics for Molluscum Contagiosum

Drugs for Molluscum Contagiosum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Pharmaceutical Solutions Phase 2, Phase 3
2 Cantharidin Investigational Phase 2 56-25-7
3 Dermatologic Agents Phase 2
4
Benzocaine Approved 1994-09-7, 94-09-7 2337
5 tannic acid Approved, Nutraceutical

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Efficacy and Tolerance of Potassium Hydroxide (10% and 15%) in Molluscum Contagiosum Completed NCT01348386 Phase 2, Phase 3 Hydroxide Potassium;Placebo
2 Safety and Efficacy Study of Topical Cantharidin for the Treatment of Molluscum Contagiosum Completed NCT02665260 Phase 2 Cantharidin;Placebo
3 Safety and Efficacy of Topical Cantharidin for the Treatment of Molluscum Contagiosum, Phase 2 Completed NCT03017846 Phase 2 Cantharidin
4 Evaluation of Systemic Exposure to VP-102 in Subjects With Molluscum Contagiosum. Recruiting NCT03186378 Phase 2 VP-102
5 A Study of VBP-245 in Pediatric Patients With Molluscum Contagiosum Recruiting NCT03077750 Phase 2 VBP-245 Topical Gel;Vehicle
6 Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo Recruiting NCT02902822 Phase 2
7 A Phase 2 Trial of a Botanical Drug for the Treatment of Molluscum Contagiosum in Pediatric Subjects Terminated NCT02024581 Phase 2 10% East Indian sandalwood oil cream;Placebo Cream
8 Efficacy of Cantharidin in Molluscum Contagiosum Completed NCT00667225 cantharidin's vehicle;Cantharidin 0.7%

Search NIH Clinical Center for Molluscum Contagiosum

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: molluscum contagiosum

Genetic Tests for Molluscum Contagiosum

Anatomical Context for Molluscum Contagiosum

MalaCards organs/tissues related to Molluscum Contagiosum:

39
Skin, T Cells, Cervix, Lung, Bone Marrow, Myeloid, Bone

Publications for Molluscum Contagiosum

Articles related to Molluscum Contagiosum:

(show top 50) (show all 608)
id Title Authors Year
1
Limited treatment options for molluscum contagiosum. ( 28768690 )
2017
2
The molluscum contagiosum virus death effector domain containing protein MC160 RxDL motifs are not required for its known viral immune evasion functions. ( 28425034 )
2017
3
Molluscum Contagiosum-Like Presentation of Langerhans Cell Histiocytosis: A Case and Review. ( 28730670 )
2017
4
Molluscum Contagiosum Virus Protein MC005 Inhibits NF-I_B Activation by Targeting NEMO-Regulated II_B Kinase Activation. ( 28490597 )
2017
5
Molecular Screening and Single Nucleotide Polymorphism Typing of Molluscum Contagiosum Virus (MCV) from Genital Specimens, between 2012 and 2015 ( 28806866 )
2017
6
Topical Imiquimod is an Effective and Safe Drug for Molluscum Contagiosum in Children. ( 28871935 )
2017
7
Disseminated molluscum contagiosum lesions in an HIV patient. ( 28322681 )
2017
8
Molluscum Contagiosum Treated with Dilute Povidone-Iodine: A Series of Cases. ( 28360968 )
2017
9
Desmoplastic trichilemmoma dermoscopically mimicking molluscum contagiosum. ( 28087019 )
2017
10
Recombination events and variability among full-length genomes of co-circulating molluscum contagiosum virus subtypes 1 and 2. ( 28555548 )
2017
11
Interventions for cutaneous molluscum contagiosum. ( 28513067 )
2017
12
Molluscum Contagiosum ( 28722927 )
2017
13
Molluscum contagiosum: an update. ( 28521677 )
2017
14
A novel homozygous DOCK8 mutation associated with unusual coexistence of gross molluscum contagiosum and epidermodysplasia verruciformis in a DOCK8 deficiency patient. ( 28670845 )
2017
15
Molluscum Contagiosum: A Rare Nipple Lesion. ( 27670745 )
2017
16
Corpora amylacea and molluscum contagiosum on a cervical pap smear. ( 27863182 )
2017
17
Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions and Inhibits NEMO Polyubiquitination. ( 28515292 )
2017
18
Topical evening primrose oil as a possible therapeutic alternative in children with molluscum contagiosum. ( 28940438 )
2017
19
Molluscum Contagiosum: Review and Update on Management. ( 28884917 )
2017
20
Molluscum Contagiosum of the Gluteal Cleft: Observations and Implications for Management in Five Children. ( 28543922 )
2017
21
Eyelid Molluscum Contagiosum Lesions in Two Patients with Unilateral Chronic Conjunctivitis. ( 28845328 )
2017
22
Melan A Antibody Cross-Reactivity in Molluscum Contagiosum Bodies. ( 28805130 )
2017
23
Filaggrin mutations and Molluscum contagiosum skin infection in patients with atopic dermatitis. ( 28866311 )
2017
24
Giant Eyelid Molluscum Contagiosum in a Child with AIDS. ( 27549877 )
2016
25
Extensive molluscum contagiosum causing obstruction of vision in HIV positive woman. ( 27294056 )
2016
26
Handheld reflectance confocal microscopy for the diagnosis of molluscum contagiosum: Histopathology and dermoscopy correlation. ( 27282954 )
2016
27
Molluscum contagiosum and associations with atopic eczema in children: a retrospective longitudinal study in primary care. ( 26639950 )
2016
28
Vascular network tightly enclosing lesions of molluscum contagiosum: Basket-like capillaries of molluscum. ( 27607603 )
2016
29
Clinical and Demographic Characteristics of Patients with Molluscum Contagiosum Treated at the University Dermatology Clinic Maribor in a 5-year period. ( 27477173 )
2016
30
Molluscum Contagiosum Infection Involving a Benign Epidermoid Cyst in an Immunocompetent Patient. ( 27319966 )
2016
31
Interventions for molluscum contagiosum in people infected with human immunodeficiency virus: a systematic review. ( 26991246 )
2016
32
Isolated giant molluscum contagiosum mimicking epidermoid cyst. ( 27648389 )
2016
33
A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction. ( 27896283 )
2016
34
Tolerability of 2.5% Lidocaine/Prilocaine Hydrogel in Children Undergoing Cryotherapy for Molluscum Contagiosum. ( 27041686 )
2016
35
Bulbar Conjunctival Molluscum Contagiosum. ( 26802706 )
2016
36
Molluscum Contagiosum. ( 27627044 )
2016
37
To Treat Molluscum Contagiosum or Not-Curettage: An Effective, Well-Accepted Treatment Modality. ( 27601304 )
2016
38
Widespread Molluscum Contagiosum with Atopic Dermatitis-like Skin Manifestations. ( 27534943 )
2016
39
Disseminated molluscum contagiosum following chemotherapy: A therapeutic challenge. ( 27852995 )
2016
40
Giant molluscum contagiosum presenting as lid neoplasm in an immunocompetent child. ( 26990479 )
2016
41
Treatment of Molluscum Contagiosum with Imiquimod in the United States: A Retrospective Cross-Sectional Study. ( 26608213 )
2016
42
Case of disseminated molluscum contagiosum caused by ruxolitinib, a Janus kinase 1 and 2 inhibitor. ( 27060215 )
2016
43
Molluscum Contagiosum Virus Transcriptome in Abortively Infected Cultured Cells and a Human Skin Lesion. ( 26889040 )
2016
44
Childhood skin and soft tissue infections: new discoveries and guidelines regarding the management of bacterial soft tissue infections, molluscum contagiosum, and warts. ( 26900921 )
2016
45
Intralesional 5-fluorouracil: Novel therapy for extensive molluscum contagiosum in an immunocompetent adult. ( 27853002 )
2016
46
Plantar Molluscum Contagiosum in an Adult Patient. ( 27269980 )
2016
47
Recalcitrant molluscum contagiosum successfully treated with sinecatechins. ( 26809498 )
2016
48
Seizures and Methemoglobinemia After Topical Application of Eutectic Mixture of Lidocaine and Prilocaine on a 3.5-Year-Old Child with Molluscum Contagiosum and Atopic Dermatitis. ( 27397059 )
2016
49
Woronoff Ring: A Novel Manifestation of Molluscum Contagiosum. ( 27871346 )
2016
50
Cytodiagnosis of disseminated histoplasmosis in an immunocompetent individual with molluscum contagiosum-like skin lesions and lymphadenopathy. ( 27756991 )
2016

Variations for Molluscum Contagiosum

Expression for Molluscum Contagiosum

Search GEO for disease gene expression data for Molluscum Contagiosum.

Pathways for Molluscum Contagiosum

GO Terms for Molluscum Contagiosum

Sources for Molluscum Contagiosum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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