MCID: MNN014
MIFTS: 43

Mononeuritis malady

Immune diseases, Blood diseases, Neuronal diseases categories

Aliases & Classifications for Mononeuritis

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Summaries for Mononeuritis

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MalaCards based summary: Mononeuritis, also known as idiopathic peripheral neuropathy, is related to mononeuritis multiplex and churg-strauss syndrome. An important gene associated with Mononeuritis is MPO (myeloperoxidase), and among its related pathways are C-MYB transcription factor network and Selenium Pathway. The compounds propylthiouracil and cytochalasin b have been mentioned in the context of this disorder. Affiliated tissues include lung, b cells and heart, and related mouse phenotype immune system.

Related Diseases for Mononeuritis

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Diseases related to Mononeuritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 1859)
idRelated DiseaseScoreTop Affiliating Genes
1mononeuritis multiplex31.7PRTN3, MPO
2churg-strauss syndrome30.7PRTN3, MPO
3polyarteritis nodosa30.7MPO, PRTN3
4nephritis30.4PRTN3, MPO
5mediastinitis30.3CRP
6vasculitis30.2CRP, PRTN3, MPO
7glomerulonephritis30.2MPO, PRTN3
8hypersensitivity vasculitis30.1PRTN3, MPO
9mononeuropathy30.1PRTN3, MPO
10neutropenia30.1PRTN3, MPO
11arthritis30.0MPO, PRTN3, CRP
12wegener granulomatosis30.0PRTN3, MPO
13acute pancreatitis29.8CRP, MPO
14acute leukemia29.8PRTN3, MPO
15hepatitis c29.8PRTN3, HSPG2
16eosinophilia29.8PRTN3, HSPG2, MPO
17rheumatoid arthritis29.7CRP, MPO, HSPG2, PRTN3
18deficiency anemia29.7PRTN3, CRP, HSPG2
19cystic fibrosis29.7MPO, HSPG2, PRTN3
20primary biliary cirrhosis29.6PRTN3, HSPG2
21systemic lupus erythematosus29.6HSPG2, PRTN3, MPO, CRP
22congenital heart disease29.6MPO, CRP
23pancreatitis29.6HSPG2, MPO, CRP
24pneumonia29.5CRP, HSPG2, MPO
25myeloid leukemia29.5MPO, PRTN3
26ulcerative colitis29.5PRTN3, CRP
27leukopenia29.4CRP, MPO
28atherosclerosis29.4HSPG2, CRP, PRTN3, MPO
29vascular disease29.4CRP, PRTN3
30proteinuria29.3CRP, PRTN3, MPO
31inflammatory bowel disease29.1MPO, CRP, PRTN3
32angioedema11.0
33hereditary hemorrhagic telangiectasia11.0
34hereditary spherocytosis11.0
35spasticity11.0
36hereditary spastic paraplegia11.0
37paraplegia11.0
38colorectal cancer10.9
39hemochromatosis10.9
40breast cancer10.9
41hereditary breast cancer10.9
42hereditary neuropathies10.8
43leber hereditary optic neuropathy10.8
44hereditary multiple exostoses10.8
45hereditary elliptocytosis10.8
46hereditary neuropathy with liability to pressure palsy10.8
47amyloidosis10.8
48ataxia10.7
49tyrosinemia10.7
50hereditary ataxia10.7

Graphical network of the top 20 diseases related to Mononeuritis:



Diseases related to mononeuritis

Symptoms for Mononeuritis

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Drugs & Therapeutics for Mononeuritis

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Drug clinical trials:

Search ClinicalTrials for Mononeuritis

Search NIH Clinical Center for Mononeuritis

Genetic Tests for Mononeuritis

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Anatomical Context for Mononeuritis

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MalaCards organs/tissues related to Mononeuritis:

31
Lung, B cells, Heart, Small intestine, Colon, Skin, Neutrophil

Animal Models for Mononeuritis or affiliated genes

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MGI Mouse Phenotypes related to Mononeuritis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.0CRP, PRTN3, MPO, HSPG2

Publications for Mononeuritis

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Articles related to Mononeuritis:

(show top 50)    (show all 134)
idTitleAuthorsYear
1
Mononeuritis multiplex associated with primary livedoid vasculopathy: Neuropathological evidence of ischemic nerve damage. (25798525)
2015
2
Mononeuritis multiplex predicts the need for immunosuppressive or immunomodulatory drugs for EGPA, PAN and MPA patients without poor-prognosis factors. (25153486)
2014
3
Mononeuritis multiplex with tumefactive cellular infiltration in a patient with reactive lymphoid hyperplasia with increased immunoglobulin G4-positive cells. (24289971)
2013
4
Paraneoplastic mononeuritis multiplex as a presenting feature of adenocarcinoma of the lung. (24455360)
2013
5
Livedoid Vasculopathy and Mononeuritis Multiplex, with a Fulminant Hepatic Failure which was caused by Herpes Simplex Hepatitis: A Case Report. (23814745)
2013
6
De novo Cryoglobulinaemic Mononeuritis Multiplex during Treatment of Chronic Hepatitis C Infection: A Viral Effect or Induced by Pegylated Interferon Alpha? (22679403)
2012
7
Vasculitic multiplex mononeuritis: polyarteritis nodosa versus cryoglobulinemic vasculitis. (20401485)
2012
8
Phrenic nerve palsy in a patient of Churg Strauss syndrome and mononeuritis multiplex. (17786498)
2008
9
Adalimumab induced mononeuritis multiplex in a patient with refractory rheumatoid arthritis: a case report. (18973686)
2008
10
Case of mononeuritis multiplex onset with rituximab therapy for WaldenstrAPm's macroglobulinemia. (17537458)
2007
11
Acro-osteolysis and mononeuritis multiplex as a presenting symptom of systemic angiitis of Wegener's type. (17401258)
2007
12
Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus. (16635678)
2006
13
Chronic inflammatory demyelinating polyneuropathy after Campylobacter jejuni infection mimicking vasculitic mononeuritis multiplex in a diabetic. (15104697)
2004
14
Orbital inflammatory pseudotumor due to hypersensitivity vasculitis and mononeuritis multiplex in a patient with atypical, cANCA-positive Wegener's granulomatosis. (12700924)
2003
15
Paediatric mononeuritis multiplex: a report of three cases and review of the literature. (14561499)
2003
16
Sensory perineuritis presented as a mononeuritis multiplex associated with livedo vasculitis. (11311480)
2001
17
Severe recalcitrant pyoderma gangrenosum responding to a combination of mycophenolate mofetil with cyclosporin and complicated by a mononeuritis. (11251582)
2001
18
Mononeuritis secondary to rheumatoid arthritis responds to etanercept. (11136899)
2000
19
Bell palsy: a herpes simplex mononeuritis? (9677123)
1998
20
A case of SjAPgren syndrome associated with multiple mononeuritis and dysautonomia including bilateral tonic pupils]. (9311000)
1997
21
Mononeuritis multiplex: a rare complication of acute hepatitis A. (8878003)
1996
22
Mononeuritis multiplex in systemic lupus erythematosus: response to pulse intravenous cyclophosphamide. (8646231)
1996
23
Angiotropic large cell lymphoma with mononeuritis multiplex mimicking systemic vasculitis. (7897423)
1995
24
Mononeuritis in two patients with limited cutaneous systemic sclerosis. (8205412)
1994
25
Hypereosinophilic syndrome presenting as recurrent benign mononeuritis multiplex. (8088985)
1994
26
Mononeuritis multiplex in a child with cutaneous polyarteritis. (1348850)
1992
27
Case-of-the-month: perineuritis presenting as mononeuritis multiplex. (1584256)
1992
28
Polyarthritis, mononeuritis multiplex and eczematous ulcerative skin rash in a patient with myelodysplastic syndrome and peripheral large granular lymphocytosis. (1722442)
1991
29
Role of macrophages in onion-bulb formation in localized hypertrophic mononeuritis (LHM). (1860270)
1991
30
BehAset's disease presenting with mononeuritis multiplex [corrected]. (2177579)
1990
31
Hypertrophic mononeuritis clinically presenting with painful legs and moving toes. (2320043)
1990
32
Vagal mononeuritis caused by herpes simplex virus: association with unilateral vocal cord paralysis. (2346163)
1990
33
Mononeuritis multiplex in incomplete BehAset's disease: a case report and the review of the literature. (2680237)
1989
34
Mononeuritis multiplex as an unusual complication of leptospirosis. (2809239)
1989
35
Periarteritis nodosa with mononeuritis multiplex. (2878916)
1986
36
Multiple mononeuritis and radiculitis with erythema, pain, elevated CSF protein and pleocytosis (Bannwarth's syndrome). (6875581)
1983
37
Perineuritis in mononeuritis multiplex with cryoglobulinemia. (7070397)
1982
38
Mononeuritis cranialis multiplex. (7346515)
1981
39
Lymphoma presenting as mononeuritis multiplex. (7329882)
1981
40
SjAPgren's syndrome and mononeuritis multiplex. (7350862)
1980
41
Isolated vagus nerve palsy and vagal mononeuritis. (7378018)
1980
42
Mononeuritis multiplex due to haemorrhage. (638684)
1978
43
WaldenstrAPm's macroglobulinemia and mononeuritis multiplex. (415654)
1978
44
Mononeuritis multiplex in lepromatous leprosy. (5690422)
1968
45
Mononeuritis multiplex in lepromatous leprosy. (4301578)
1968
46
Mononeuritis in association with malignancy. (5977425)
1966
47
MONONEURITIS MULTIPLEX IN POLYARTERITIS NODOSA. (14144116)
1964
48
MONONEURITIS MULTIPLEX IN POLYARTERITIS NODOSA. (14045124)
1963
49
ELECTROMYOGRAPHIC STUDY ON SO-CALLED MONONEURITIS. (14049405)
1963
50
Heredofamilial mononeuritis multiplex with brachial predilection. (13837190)
1960

Variations for Mononeuritis

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Expression for genes affiliated with Mononeuritis

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Search GEO for disease gene expression data for Mononeuritis.

Pathways for genes affiliated with Mononeuritis

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Pathways related to Mononeuritis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4PRTN3, MPO
2
Show member pathways
thioredoxin pathway36
9.3CRP, MPO

Compounds for genes affiliated with Mononeuritis

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Compounds related to Mononeuritis according to GeneCards Suite gene sharing:

(show all 42)
idCompoundScoreTop Affiliating Genes
1propylthiouracil43 2 1211.8MPO, PRTN3
2cytochalasin b439.8MPO, PRTN3
3aopp439.8MPO, CRP
4sulfasalazine28 43 49 1212.7MPO, CRP
58-isoprostane439.7CRP, MPO
6methacholine43 49 1211.7CRP, MPO
7infliximab43 49 1211.7CRP, PRTN3
8vitamin b12439.7CRP, MPO
9malondialdehyde439.7CRP, MPO
10rituximab43 49 1211.7PRTN3, CRP
11formaldehyde43 2410.7PRTN3, MPO
12polyethylene glycol439.7MPO, CRP
13clozapine43 28 49 1212.6CRP, MPO
14azathioprine43 2 49 1212.6CRP, PRTN3
15p002439.6CRP, PRTN3
16valine439.6PRTN3, MPO
17prednisolone43 28 1211.6CRP, MPO
18cyclophosphamide43 49 1211.6CRP, MPO
19propranolol43 28 49 24 1213.5MPO, HSPG2
20convulxin439.4CRP, HSPG2
21prostaglandin f2alpha439.4HSPG2, CRP
22chloramphenicol43 2 49 1212.4CRP, MPO
23losartan43 49 28 1212.4HSPG2, CRP
24simvastatin43 49 59 28 24 1214.3HSPG2, CRP
25phosphatidylserine43 28 1211.3PRTN3, HSPG2
26prostacyclin439.2HSPG2, CRP
27n acetylcysteine439.2MPO, CRP
28aspirin43 49 28 2412.1HSPG2, CRP
29histamine43 28 2411.1MPO, HSPG2
30n-formylmethionyl-leucylphenylalanine439.0PRTN3, MPO, HSPG2
31fmlp439.0PRTN3, MPO, HSPG2
32dmso439.0HSPG2, MPO, PRTN3
33d penicillamine438.9CRP, MPO, HSPG2
34ascorbic acid43 249.9CRP, MPO, HSPG2
35acetylcholine43 49 28 24 1212.9CRP, MPO, HSPG2
36cycloheximide438.9HSPG2, PRTN3, CRP
37retinoic acid43 249.9HSPG2, MPO, PRTN3
38vegf438.9CRP, MPO, HSPG2
39alanine438.8CRP, PRTN3, HSPG2
40indomethacin43 28 59 1211.8MPO, HSPG2
41serine438.6PRTN3, MPO, HSPG2
42calcium43 49 24 1211.4CRP, PRTN3, MPO, HSPG2

GO Terms for genes affiliated with Mononeuritis

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Cellular components related to Mononeuritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrixGO:00310128.8PRTN3, HSPG2
2extracellular vesicular exosomeGO:00700628.6PRTN3, MPO, HSPG2
3extracellular spaceGO:00056158.4CRP, MPO, HSPG2

Biological processes related to Mononeuritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1agingGO:00075689.3CRP, MPO

Molecular functions related to Mononeuritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1metal ion bindingGO:00468728.5CRP, MPO, HSPG2

Products for genes affiliated with Mononeuritis

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Sources for Mononeuritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet