MCID: MNN002
MIFTS: 33

Mononeuritis Multiplex malady

Summaries for Mononeuritis Multiplex

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63Wikipedia, 32MalaCards
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Wikipedia:63 Peripheral neuropathy (PN) is damage or disease affecting nerves, which may affect sensation, movement,... more...

MalaCards: Mononeuritis Multiplex is related to vasculitis and polyarteritis nodosa. An important gene associated with Mononeuritis Multiplex is MPO (myeloperoxidase), and among its related pathways are C-MYB transcription factor network and Selenium Pathway. The compounds cytochalasin b and n-formylmethionyl-leucylphenylalanine have been mentioned in the context of this disorder. Affiliated tissues include b cells, skin and lung.

Aliases & Classifications for Mononeuritis Multiplex

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8Disease Ontology, 42NIH Rare Diseases, 44Novoseek, 60UMLS, 39NCIt, 34MeSH, 27ICD9CM, 56SNOMED-CT
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Aliases & Descriptions:

mononeuritis multiplex 8 42 44 60


External Ids:

Disease Ontology8 DOID:1835
NCIt39 C70938
SNOMED-CT56 30292005
MeSH34 D020422
ICD9CM27 354.5

Related Diseases for Mononeuritis Multiplex

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17GeneCards, 18GeneDecks
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Diseases related to Mononeuritis Multiplex via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 115)
idRelated DiseaseScoreTop Affiliating Genes
1vasculitis30.7MPO, PRTN3, CRP
2polyarteritis nodosa30.6MPO, PRTN3
3churg-strauss syndrome30.6MPO, PRTN3
4rheumatoid arthritis30.5PRTN3, MPO, CRP
5arthritis30.5CRP, MPO, PRTN3
6systemic lupus erythematosus30.5CRP
7hepatitis c30.1PRTN3
8hypersensitivity vasculitis30.1PRTN3, MPO
9wegener's granulomatosis30.1MPO, PRTN3
10mononeuropathy30.1PRTN3, MPO
11acute leukemia30.1MPO, PRTN3
12asthma30.1PRTN3, MPO
13eosinophilia30.1MPO, PRTN3
14mononeuritis11.1
15hepatitis10.4
16macroglobulinemia10.3
17leptospirosis10.3
18hepatitis a10.3
19leprosy10.3
20lupus erythematosus10.3
21cryoglobulinemia10.2
22lepromatous leprosy10.2
23chronic polyneuropathy10.2
24demyelinating polyneuropathy10.2
25mononeuritis of upper limb and mononeuritis multiplex10.2
26neuropathy10.2
27polyneuropathy10.2
28purpura10.2
29hereditary neuralgic amyotrophy10.2
30central retinal artery occlusion10.1
31plasmodium malariae malaria10.1
32kimura disease10.1
33neurofibromatosis10.1
34acalculous cholecystitis10.1
35granulomatous angiitis10.1
36diabetic polyneuropathy10.1
37q fever10.1
38aseptic meningitis10.1
39small cell carcinoma10.1
40lyme disease10.1
41hepatitis b10.1
42infectious mononucleosis10.1
43typhoid fever10.1
44scrub typhus10.1
45plasmodium falciparum malaria10.1
46horner's syndrome10.1
47aphasia10.1
48brachial plexus neuropathy10.1
49cholecystitis10.1
50diabetes mellitus10.1

Graphical network of the top 20 diseases related to Mononeuritis Multiplex:



Diseases related to mononeuritis multiplex

Clinical Features for Mononeuritis Multiplex

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Drugs & Therapeutics for Mononeuritis Multiplex

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Mononeuritis Multiplex

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Anatomical Context for Mononeuritis Multiplex

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32MalaCards
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MalaCards organs/tissues related to Mononeuritis Multiplex:

32
B cells, Skin, Lung, Heart, Small intestine, Colon

Animal Models for Mononeuritis Multiplex or affiliated genes

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Publications for Mononeuritis Multiplex

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50PubMed
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Articles related to Mononeuritis Multiplex:

(show top 50)    (show all 109)
idTitleAuthorsYear
1
Mononeuritis multiplex with tumefactive cellular infiltration in a patient with reactive lymphoid hyperplasia with increased immunoglobulin G4-positive cells. (24289971)
2013
2
Neurosarcoidosis Presenting as Mononeuritis Multiplex. (24196972)
2013
3
Mononeuritis multiplex in a patient with B-cell prolymphocytic leukaemia: a diagnostic challenge. (24000206)
2013
4
Vasculitic multiplex mononeuritis: polyarteritis nodosa versus cryoglobulinemic vasculitis. (20401485)
2012
5
Mononeuritis multiplex complicating systemic lupus erythematosus. (22885442)
2012
6
A case of scrub typhus with acalculous cholecystitis, aseptic meningitis and mononeuritis multiplex. (21940653)
2012
7
Kimura disease with necrosis of the limbs and mononeuritis multiplex. (21418278)
2011
8
A case of MPO-ANCA-positive polyarteritis nodosa complicated by exudative otitis media, mononeuritis multiplex, and acute renal failure. (21611757)
2011
9
Extreme hypereosinophilia, Churg-Strauss syndrome and mononeuritis multiplex. (21869702)
2011
10
Cutaneous large B-cell lymphoma of the leg: presenting initially as mononeuritis multiplex. (19495496)
2009
11
Adalimumab induced mononeuritis multiplex in a patient with refractory rheumatoid arthritis: a case report. (18973686)
2008
12
Case of mononeuritis multiplex onset with rituximab therapy for WaldenstrAPm's macroglobulinemia. (17537458)
2007
13
Infliximab-associated neuropathy in RA patients--the importance of considering the diagnosis of mononeuritis multiplex. (17063281)
2007
14
Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus. (16635678)
2006
15
Paraneoplastic mononeuritis multiplex in non-small-cell lung carcinoma. (16564174)
2006
16
Severe proximal myopathy and mononeuritis multiplex in rheumatoid arthritis: manifestations of rheumatoid vasculitis. (16357697)
2005
17
Painful mononeuritis multiplex in idiopathic thrombocytopenic purpura. (15995289)
2005
18
Chronic inflammatory demyelinating polyneuropathy after Campylobacter jejuni infection mimicking vasculitic mononeuritis multiplex in a diabetic. (15104697)
2004
19
A rare cause for mononeuritis multiplex. (15069271)
2004
20
Mononeuritis multiplex in diabetes mellitus: evidence for underlying immune pathogenesis. (12754358)
2003
21
Successful treatment of refractory mononeuritis multiplex secondary to rheumatoid arthritis with the anti-tumour necrosis factor alpha monoclonal antibody infliximab. (11886980)
2002
22
Sensory perineuritis presented as a mononeuritis multiplex associated with livedo vasculitis. (11311480)
2001
23
Localized neurological necrotizing vasculitides. Three cases with isolated mononeuritis multiplex. (11296972)
2001
24
Pronator Teres Syndrome Associated with Mononeuritis Multiplex in Polyarteritis Nodosa. (11089179)
1999
25
Hypereosinophilic syndrome presenting as recurrent benign mononeuritis multiplex. (8088985)
1994
26
Mononeuritis multiplex. A harbinger of acute leukemia in relapse. (8198473)
1994
27
Mononeuritis multiplex and vasculitis. Association with anti-neutrophil cytoplasmic autoantibody. (8198467)
1994
28
Mononeuritis multiplex after coelenterate sting. (7830670)
1994
29
Unusual neurologic complications of typhoid fever (aphasia, mononeuritis multiplex, and Guillain-BarrAc syndrome): a report of two cases. (8249195)
1993
30
Nonvasculitic, steroid-responsive mononeuritis multiplex. (8492941)
1993
31
A case of neurofibromatosis 2 presenting with a mononeuritis multiplex. (1602313)
1992
32
Vasculitic mononeuritis multiplex in patient with Lyme disease. (1649149)
1991
33
Mononeuritis multiplex in incomplete BehAset's disease: a case report and the review of the literature. (2680237)
1989
34
Mononeuritis multiplex: the yield of evaluations for occult rheumatic diseases. (2835572)
1988
35
Periarteritis nodosa with mononeuritis multiplex. (2878916)
1986
36
Giant cell arteritis associated with mononeuritis multiplex and complement-activating 19S IgM rheumatoid factor. (3728548)
1986
37
Plasma exchange in a patient with severe rheumatoid arthritis complicated by mononeuritis multiplex and cutaneous ulcers. (3960239)
1986
38
Giant cell arteritis associated with mononeuritis multiplex and complement-activating 19S IgM rheumatoid factor. (2996347)
1985
39
Mononeuritis multiplex and eosinophilia in a patient with asthma. (4014784)
1985
40
Perineuritis in mononeuritis multiplex with cryoglobulinemia. (7070397)
1982
41
Multiple mononeuropathy or mononeuritis multiplex in diabetics? (7072444)
1982
42
Mononeuritis cranialis multiplex. (7346515)
1981
43
Mononeuritis multiplex in a patient with macroglobulinaemia. (825616)
1976
44
Mononeuritis multiplex associated with infectious mononucleosis. (4426004)
1974
45
Neuroclinical-pathology conference: Progressive bilateral lower limb weakness and cranial mononeuritis multiplex. (4405881)
1974
46
Mononeuritis multiplex occurring in a diabetic patient with Hb C disease. (4704497)
1973
47
Mononeuritis multiplex in lepromatous leprosy. (5690422)
1968
48
Mononeuritis multiplex in lepromatous leprosy. (4301578)
1968
49
Mononeuritis multiplex complicating the post-perfusion syndrome. (5701924)
1968
50
Heredofamilial mononeuritis multiplex with brachial predilection. (13837190)
1960

Genetic Variations for Mononeuritis Multiplex

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Expression for genes affiliated with Mononeuritis Multiplex

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mononeuritis Multiplex

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Pathways for genes affiliated with Mononeuritis Multiplex

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37NCBI BioSystems Database
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Pathways related to Mononeuritis Multiplex according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3PRTN3, MPO
29.0MPO, CRP

Compounds for genes affiliated with Mononeuritis Multiplex

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44Novoseek, 49PharmGKB, 11DrugBank, 28IUPHAR, 24HMDB, 2BitterDB
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Compounds related to Mononeuritis Multiplex according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1cytochalasin b449.6PRTN3, MPO
2n-formylmethionyl-leucylphenylalanine449.6PRTN3, MPO
3infliximab44 49 1111.4CRP, PRTN3
4aopp449.4MPO, CRP
5rituximab44 49 1111.4CRP, PRTN3
6d penicillamine449.4MPO, CRP
7sulfasalazine44 28 49 1112.4MPO, CRP
88-isoprostane449.4CRP, MPO
9formaldehyde44 2410.3PRTN3, MPO
10methacholine44 1110.3CRP, MPO
11azathioprine44 49 2 1112.3CRP, PRTN3
12vitamin b12449.3MPO, CRP
13malondialdehyde449.3MPO, CRP
14p002449.3PRTN3, CRP
15polyethylene glycol449.3MPO, CRP
16clozapine44 28 49 1112.2MPO, CRP
17fmlp449.2MPO, PRTN3
18prednisolone44 28 1111.1CRP, MPO
19cyclophosphamide44 49 1111.1MPO, CRP
20chloramphenicol44 2 1111.0MPO, CRP
21dmso449.0PRTN3, MPO

GO Terms for genes affiliated with Mononeuritis Multiplex

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Products for genes affiliated with Mononeuritis Multiplex

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Sources for Mononeuritis Multiplex

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet