MCID: MNN002
MIFTS: 33

Mononeuritis Multiplex malady

Rare diseases, Neuronal diseases categories

Aliases & Classifications for Mononeuritis Multiplex

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Mononeuritis Multiplex, Aliases & Descriptions:

Name: Mononeuritis Multiplex 9 41 43 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases


External Ids:

Disease Ontology9 DOID:1835
NCIt38 C70938
MeSH33 D020422
SNOMED-CT55 30292005
ICD9CM27 354.5
ICD1025 G58.7

Summaries for Mononeuritis Multiplex

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Wikipedia:63 Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation,... more...

MalaCards based summary: Mononeuritis Multiplex is related to polyarteritis nodosa and churg-strauss syndrome. An important gene associated with Mononeuritis Multiplex is MPO (myeloperoxidase), and among its related pathways are C-MYB transcription factor network and Selenium Pathway. The compounds propylthiouracil and cytochalasin b have been mentioned in the context of this disorder. Affiliated tissues include lung, b cells and heart, and related mouse phenotype immune system.

Related Diseases for Mononeuritis Multiplex

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Graphical network of the top 20 diseases related to Mononeuritis Multiplex:



Diseases related to mononeuritis multiplex

Symptoms for Mononeuritis Multiplex

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Drugs & Therapeutics for Mononeuritis Multiplex

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Drug clinical trials:

Search ClinicalTrials for Mononeuritis Multiplex

Search NIH Clinical Center for Mononeuritis Multiplex

Genetic Tests for Mononeuritis Multiplex

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Anatomical Context for Mononeuritis Multiplex

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MalaCards organs/tissues related to Mononeuritis Multiplex:

31
Lung, B cells, Heart, Small intestine, Colon, Skin, Neutrophil

Animal Models for Mononeuritis Multiplex or affiliated genes

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MGI Mouse Phenotypes related to Mononeuritis Multiplex:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.5CRP, PRTN3, MPO

Publications for Mononeuritis Multiplex

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Articles related to Mononeuritis Multiplex:

(show top 50)    (show all 114)
idTitleAuthorsYear
1
Mononeuritis multiplex associated with primary livedoid vasculopathy: Neuropathological evidence of ischemic nerve damage. (25798525)
2015
2
Mononeuritis multiplex predicts the need for immunosuppressive or immunomodulatory drugs for EGPA, PAN and MPA patients without poor-prognosis factors. (25153486)
2014
3
Mononeuritis multiplex with tumefactive cellular infiltration in a patient with reactive lymphoid hyperplasia with increased immunoglobulin G4-positive cells. (24289971)
2013
4
Paraneoplastic mononeuritis multiplex as a presenting feature of adenocarcinoma of the lung. (24455360)
2013
5
Livedoid Vasculopathy and Mononeuritis Multiplex, with a Fulminant Hepatic Failure which was caused by Herpes Simplex Hepatitis: A Case Report. (23814745)
2013
6
Treatment for cutaneous arteritis patients with mononeuritis multiplex and elevated C-reactive protein. (24303898)
2013
7
An unusual cause of mononeuritis multiplex. (23315459)
2013
8
De novo Cryoglobulinaemic Mononeuritis Multiplex during Treatment of Chronic Hepatitis C Infection: A Viral Effect or Induced by Pegylated Interferon Alpha? (22679403)
2012
9
Mononeuritis multiplex complicating systemic lupus erythematosus. (22885442)
2012
10
A case of scrub typhus with acalculous cholecystitis, aseptic meningitis and mononeuritis multiplex. (21940653)
2012
11
Cutaneous large B-cell lymphoma of the leg: presenting initially as mononeuritis multiplex. (19495496)
2009
12
Phrenic nerve palsy in a patient of Churg Strauss syndrome and mononeuritis multiplex. (17786498)
2008
13
Adalimumab induced mononeuritis multiplex in a patient with refractory rheumatoid arthritis: a case report. (18973686)
2008
14
A purpuric rash and mononeuritis multiplex. (18326170)
2008
15
Case of mononeuritis multiplex onset with rituximab therapy for WaldenstrAPm's macroglobulinemia. (17537458)
2007
16
Acro-osteolysis and mononeuritis multiplex as a presenting symptom of systemic angiitis of Wegener's type. (17401258)
2007
17
Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus. (16635678)
2006
18
Chronic inflammatory demyelinating polyneuropathy after Campylobacter jejuni infection mimicking vasculitic mononeuritis multiplex in a diabetic. (15104697)
2004
19
Orbital inflammatory pseudotumor due to hypersensitivity vasculitis and mononeuritis multiplex in a patient with atypical, cANCA-positive Wegener's granulomatosis. (12700924)
2003
20
Paediatric mononeuritis multiplex: a report of three cases and review of the literature. (14561499)
2003
21
Sensory perineuritis presented as a mononeuritis multiplex associated with livedo vasculitis. (11311480)
2001
22
Th2 shift in mononeuritis multiplex and increase of Th2 cells in chronic inflammatory demyelinating polyneuropathy: an intracellular cytokine analysis. (11718750)
2001
23
Horner's syndrome associated with mononeuritis multiplex due to cytomegalovirus as the initial manifestation in a patient with AIDS. (9543329)
1998
24
Mononeuritis multiplex: a rare complication of acute hepatitis A. (8878003)
1996
25
Mononeuritis multiplex in systemic lupus erythematosus: response to pulse intravenous cyclophosphamide. (8646231)
1996
26
Angiotropic large cell lymphoma with mononeuritis multiplex mimicking systemic vasculitis. (7897423)
1995
27
Hypereosinophilic syndrome presenting as recurrent benign mononeuritis multiplex. (8088985)
1994
28
Mononeuritis multiplex. A harbinger of acute leukemia in relapse. (8198473)
1994
29
Mononeuritis multiplex and vasculitis. Association with anti-neutrophil cytoplasmic autoantibody. (8198467)
1994
30
Churg-Strauss syndrome (allergic granulomatous angiitis) with multiple perforating ulcers of the small intestine, multiple ulcers of the colon, and mononeuritis multiplex. (8012511)
1994
31
Mononeuritis multiplex in a child with cutaneous polyarteritis. (1348850)
1992
32
Case-of-the-month: perineuritis presenting as mononeuritis multiplex. (1584256)
1992
33
Mononeuritis multiplex associated with cryoglobulinemia in HIV infection. (1436518)
1992
34
Polyarthritis, mononeuritis multiplex and eczematous ulcerative skin rash in a patient with myelodysplastic syndrome and peripheral large granular lymphocytosis. (1722442)
1991
35
BehAset's disease presenting with mononeuritis multiplex [corrected]. (2177579)
1990
36
Mononeuritis multiplex in incomplete BehAset's disease: a case report and the review of the literature. (2680237)
1989
37
Mononeuritis multiplex as an unusual complication of leptospirosis. (2809239)
1989
38
Periarteritis nodosa with mononeuritis multiplex. (2878916)
1986
39
Giant cell arteritis associated with mononeuritis multiplex and complement-activating 19S IgM rheumatoid factor. (3728548)
1986
40
Perineuritis in mononeuritis multiplex with cryoglobulinemia. (7070397)
1982
41
Lymphoma presenting as mononeuritis multiplex. (7329882)
1981
42
SjAPgren's syndrome and mononeuritis multiplex. (7350862)
1980
43
Mononeuritis multiplex due to haemorrhage. (638684)
1978
44
WaldenstrAPm's macroglobulinemia and mononeuritis multiplex. (415654)
1978
45
Mononeuritis multiplex occurring in a diabetic patient with Hb C disease. (4704497)
1973
46
Mononeuritis multiplex in lepromatous leprosy. (5690422)
1968
47
Mononeuritis multiplex in lepromatous leprosy. (4301578)
1968
48
MONONEURITIS MULTIPLEX IN POLYARTERITIS NODOSA. (14144116)
1964
49
MONONEURITIS MULTIPLEX IN POLYARTERITIS NODOSA. (14045124)
1963
50
Heredofamilial mononeuritis multiplex with brachial predilection. (13837190)
1960

Variations for Mononeuritis Multiplex

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Expression for genes affiliated with Mononeuritis Multiplex

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Search GEO for disease gene expression data for Mononeuritis Multiplex.

Pathways for genes affiliated with Mononeuritis Multiplex

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Pathways related to Mononeuritis Multiplex according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3PRTN3, MPO
2
Show member pathways
thioredoxin pathway36
9.0CRP, MPO

Compounds for genes affiliated with Mononeuritis Multiplex

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Sources:
43Novoseek, 2BitterDB, 12DrugBank, 24HMDB, 49PharmGKB, 28IUPHAR
See all sources

Compounds related to Mononeuritis Multiplex according to GeneCards Suite gene sharing:

(show all 32)
idCompoundScoreTop Affiliating Genes
1propylthiouracil43 2 1211.7PRTN3, MPO
2cytochalasin b439.7PRTN3, MPO
3n-formylmethionyl-leucylphenylalanine439.7MPO, PRTN3
4formaldehyde43 2410.6PRTN3, MPO
5fmlp439.6PRTN3, MPO
6valine439.6MPO, PRTN3
7dmso439.6PRTN3, MPO
8infliximab43 49 1211.5CRP, PRTN3
9rituximab43 49 1211.5CRP, PRTN3
10azathioprine43 2 49 1212.5CRP, PRTN3
11p002439.4CRP, PRTN3
12aopp439.4CRP, MPO
13d penicillamine439.4CRP, MPO
14sulfasalazine28 43 49 1212.4CRP, MPO
158-isoprostane439.4MPO, CRP
16methacholine43 49 1211.4CRP, MPO
17nadph43 2410.4PRTN3, MPO
18vitamin b12439.4CRP, MPO
19malondialdehyde439.4CRP, MPO
20polyethylene glycol439.4MPO, CRP
21clozapine43 28 49 1212.4CRP, MPO
22prednisolone43 28 1211.3MPO, CRP
23cyclophosphamide43 49 1211.3CRP, MPO
24chloramphenicol43 2 49 1212.3CRP, MPO
25n acetylcysteine439.2CRP, MPO
26ascorbic acid43 2410.2MPO, CRP
27acetylcholine43 49 28 24 1213.2CRP, MPO
28iron43 2410.0MPO, CRP
29creatinine439.0CRP, MPO
30superoxide43 2410.0PRTN3, MPO
31lactate438.9CRP, MPO
32calcium43 49 24 1211.6CRP, PRTN3, MPO

GO Terms for genes affiliated with Mononeuritis Multiplex

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Biological processes related to Mononeuritis Multiplex according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1agingGO:00075689.0CRP, MPO

Products for genes affiliated with Mononeuritis Multiplex

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  • Kits and Assays

Sources for Mononeuritis Multiplex

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet