MCID: MNN002
MIFTS: 33

Mononeuritis Multiplex malady

Summaries for Mononeuritis Multiplex

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63Wikipedia, 32MalaCards
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Wikipedia:63 Peripheral neuropathy (PN) is damage or disease affecting nerves, which may affect sensation, movement,... more...

MalaCards: Mononeuritis Multiplex is related to vasculitis and polyarteritis nodosa. An important gene associated with Mononeuritis Multiplex is MPO (myeloperoxidase), and among its related pathways are C-MYB transcription factor network and Selenium Pathway. The compounds cytochalasin b and n-formylmethionyl-leucylphenylalanine have been mentioned in the context of this disorder. Affiliated tissues include b cells, heart and small intestine.

Aliases & Classifications for Mononeuritis Multiplex

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8Disease Ontology, 42NIH Rare Diseases, 44Novoseek, 60UMLS, 39NCIt, 34MeSH, 27ICD9CM, 56SNOMED-CT
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Aliases & Descriptions:

mononeuritis multiplex 8 42 44 60


External Ids:

Disease Ontology8 DOID:1835
NCIt39 C70938
SNOMED-CT56 30292005
MeSH34 D020422
ICD9CM27 354.5

Related Diseases for Mononeuritis Multiplex

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17GeneCards, 18GeneDecks
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Diseases related to Mononeuritis Multiplex via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 115)
idRelated DiseaseScoreTop Affiliating Genes
1vasculitis30.7MPO, PRTN3, CRP
2polyarteritis nodosa30.6MPO, PRTN3
3churg-strauss syndrome30.6MPO, PRTN3
4rheumatoid arthritis30.5PRTN3, MPO, CRP
5arthritis30.5CRP, MPO, PRTN3
6systemic lupus erythematosus30.5CRP
7hepatitis c30.1PRTN3
8hypersensitivity vasculitis30.1PRTN3, MPO
9wegener's granulomatosis30.1MPO, PRTN3
10mononeuropathy30.1PRTN3, MPO
11acute leukemia30.1MPO, PRTN3
12asthma30.1PRTN3, MPO
13eosinophilia30.1MPO, PRTN3
14mononeuritis11.1
15hepatitis10.4
16macroglobulinemia10.3
17leptospirosis10.3
18hepatitis a10.3
19leprosy10.3
20lupus erythematosus10.3
21cryoglobulinemia10.2
22lepromatous leprosy10.2
23chronic polyneuropathy10.2
24demyelinating polyneuropathy10.2
25mononeuritis of upper limb and mononeuritis multiplex10.2
26neuropathy10.2
27polyneuropathy10.2
28purpura10.2
29hereditary neuralgic amyotrophy10.2
30central retinal artery occlusion10.1
31plasmodium malariae malaria10.1
32kimura disease10.1
33neurofibromatosis10.1
34acalculous cholecystitis10.1
35granulomatous angiitis10.1
36diabetic polyneuropathy10.1
37q fever10.1
38aseptic meningitis10.1
39small cell carcinoma10.1
40lyme disease10.1
41hepatitis b10.1
42infectious mononucleosis10.1
43typhoid fever10.1
44scrub typhus10.1
45plasmodium falciparum malaria10.1
46horner's syndrome10.1
47aphasia10.1
48brachial plexus neuropathy10.1
49cholecystitis10.1
50diabetes mellitus10.1

Graphical network of the top 20 diseases related to Mononeuritis Multiplex:



Diseases related to mononeuritis multiplex

Clinical Features for Mononeuritis Multiplex

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Drugs & Therapeutics for Mononeuritis Multiplex

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Mononeuritis Multiplex

Drug clinical trials:

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Genetic Tests for Mononeuritis Multiplex

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Anatomical Context for Mononeuritis Multiplex

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32MalaCards
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MalaCards organs/tissues related to Mononeuritis Multiplex:

32
B cells, Heart, Small intestine, Colon, Lung, Skin

Animal Models for Mononeuritis Multiplex or affiliated genes

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Publications for Mononeuritis Multiplex

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50PubMed
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Articles related to Mononeuritis Multiplex:

(show top 50)    (show all 109)
idTitleAuthorsYear
1
Livedoid Vasculopathy and Mononeuritis Multiplex, with a Fulminant Hepatic Failure which was caused by Herpes Simplex Hepatitis: A Case Report. (23814745)
2013
2
An unusual cause of mononeuritis multiplex. (23315459)
2013
3
Mononeuritis multiplex and painful ulcers as the initial manifestation of hepatitis B infection. (23645658)
2013
4
De novo Cryoglobulinaemic Mononeuritis Multiplex during Treatment of Chronic Hepatitis C Infection: A Viral Effect or Induced by Pegylated Interferon Alpha? (22679403)
2012
5
Mononeuritis multiplex due to leprosy: A case of atypical presentation. (23274120)
2012
6
Light chain deposition in peripheral nerve as a cause of mononeuritis multiplex in WaldenstrAPm's macroglobulinaemia. (20149395)
2010
7
An unusual case of relapsing remitting mononeuritis multiplex. (22750923)
2010
8
Pruritic, papular eruption, and concomitant neurologic symptoms: Churg-Strauss syndrome presenting with mononeuritis multiplex. (20527147)
2010
9
A case of suspected mononeuritis multiplex in a teenager from polysubstance abuse. (19769924)
2009
10
Phrenic nerve palsy in a patient of Churg Strauss syndrome and mononeuritis multiplex. (17786498)
2008
11
Case of mononeuritis multiplex onset with rituximab therapy for WaldenstrAPm's macroglobulinemia. (17537458)
2007
12
Acro-osteolysis and mononeuritis multiplex as a presenting symptom of systemic angiitis of Wegener's type. (17401258)
2007
13
Mononeuritis multiplex as a presenting feature of Wegener granulomatosis: a case report. (17115101)
2007
14
A rare cause for mononeuritis multiplex. (15069271)
2004
15
Orbital inflammatory pseudotumor due to hypersensitivity vasculitis and mononeuritis multiplex in a patient with atypical, cANCA-positive Wegener's granulomatosis. (12700924)
2003
16
Paediatric mononeuritis multiplex: a report of three cases and review of the literature. (14561499)
2003
17
Mononeuritis multiplex caused by Coxiella burnetii infection (Q fever). (12460144)
2002
18
Th2 shift in mononeuritis multiplex and increase of Th2 cells in chronic inflammatory demyelinating polyneuropathy: an intracellular cytokine analysis. (11718750)
2001
19
Joint and muscle pain with mononeuritis multiplex, tetraparesis, and myocardial infarction in a previously healthy adult. (11602463)
2001
20
Neurolymphomatosis presenting as mononeuritis multiplex. (18639200)
1999
21
Pronator Teres Syndrome Associated with Mononeuritis Multiplex in Polyarteritis Nodosa. (11089179)
1999
22
Horner's syndrome associated with mononeuritis multiplex due to cytomegalovirus as the initial manifestation in a patient with AIDS. (9543329)
1998
23
Churg-Strauss syndrome associated with third nerve palsy and mononeuritis multiplex of the legs. (7656494)
1995
24
Mononeuritis multiplex and vasculitis. Association with anti-neutrophil cytoplasmic autoantibody. (8198467)
1994
25
Churg-Strauss syndrome (allergic granulomatous angiitis) with multiple perforating ulcers of the small intestine, multiple ulcers of the colon, and mononeuritis multiplex. (8012511)
1994
26
Mononeuritis multiplex complicating Henoch-Schonlein purpura. (7848168)
1994
27
Mononeuritis multiplex in a child with cutaneous polyarteritis. (1348850)
1992
28
Case-of-the-month: perineuritis presenting as mononeuritis multiplex. (1584256)
1992
29
Mononeuritis multiplex associated with cryoglobulinemia in HIV infection. (1436518)
1992
30
A case of neurofibromatosis 2 presenting with a mononeuritis multiplex. (1602313)
1992
31
Polyarthritis, mononeuritis multiplex and eczematous ulcerative skin rash in a patient with myelodysplastic syndrome and peripheral large granular lymphocytosis. (1722442)
1991
32
Mononeuritis multiplex in leptospirosis. (1882206)
1991
33
Morphoea and mononeuritis multiplex. (1851234)
1991
34
BehAset's disease presenting with mononeuritis multiplex [corrected]. (2177579)
1990
35
Mononeuritis multiplex associated with prolonged vancomycin treatment. (2164433)
1990
36
Mononeuritis multiplex in incomplete BehAset's disease: a case report and the review of the literature. (2680237)
1989
37
Mononeuritis multiplex as an unusual complication of leptospirosis. (2809239)
1989
38
Mononeuritis multiplex with brachial plexus neuropathy coincident with Mycoplasma pneumoniae infection. (2540009)
1989
39
Immunoglobulin M deposits in sural nerve in mononeuritis multiplex associated with immunoglobulin M paraproteinemia. (2853607)
1988
40
Mononeuritis multiplex in WaldenstrAPm's macroglobulinemia. (3116914)
1987
41
Giant cell arteritis associated with mononeuritis multiplex and complement-activating 19S IgM rheumatoid factor. (2996347)
1985
42
Mononeuritis multiplex following jellyfish stings. (6142678)
1984
43
Mononeuritis cranialis multiplex. (7346515)
1981
44
Lymphoma presenting as mononeuritis multiplex. (7329882)
1981
45
SjAPgren's syndrome and mononeuritis multiplex. (7350862)
1980
46
WaldenstrAPm's macroglobulinemia and mononeuritis multiplex. (415654)
1978
47
Mononeuritis multiplex: a complication of open-heart surgery. (1127981)
1975
48
MONONEURITIS MULTIPLEX IN POLYARTERITIS NODOSA. (14144116)
1964
49
MONONEURITIS MULTIPLEX. (14250833)
1964
50
MONONEURITIS MULTIPLEX IN POLYARTERITIS NODOSA. (14045124)
1963

Genetic Variations for Mononeuritis Multiplex

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Expression for genes affiliated with Mononeuritis Multiplex

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mononeuritis Multiplex

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Pathways for genes affiliated with Mononeuritis Multiplex

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37NCBI BioSystems Database
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Pathways related to Mononeuritis Multiplex according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3PRTN3, MPO
29.0MPO, CRP

Compounds for genes affiliated with Mononeuritis Multiplex

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44Novoseek, 49PharmGKB, 11DrugBank, 28IUPHAR, 24HMDB, 2BitterDB
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Compounds related to Mononeuritis Multiplex according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1cytochalasin b449.6PRTN3, MPO
2n-formylmethionyl-leucylphenylalanine449.6PRTN3, MPO
3infliximab44 49 1111.4CRP, PRTN3
4aopp449.4MPO, CRP
5rituximab44 49 1111.4CRP, PRTN3
6d penicillamine449.4MPO, CRP
7sulfasalazine44 28 49 1112.4MPO, CRP
88-isoprostane449.4CRP, MPO
9formaldehyde44 2410.3PRTN3, MPO
10methacholine44 1110.3CRP, MPO
11azathioprine44 49 2 1112.3CRP, PRTN3
12vitamin b12449.3MPO, CRP
13malondialdehyde449.3MPO, CRP
14p002449.3PRTN3, CRP
15polyethylene glycol449.3MPO, CRP
16clozapine44 28 49 1112.2MPO, CRP
17fmlp449.2MPO, PRTN3
18prednisolone44 28 1111.1CRP, MPO
19cyclophosphamide44 49 1111.1MPO, CRP
20chloramphenicol44 2 1111.0MPO, CRP
21dmso449.0PRTN3, MPO

GO Terms for genes affiliated with Mononeuritis Multiplex

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Products for genes affiliated with Mononeuritis Multiplex

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Sources for Mononeuritis Multiplex

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet