MCID: MNN017
MIFTS: 39

Mononeuropathy malady

Neuronal diseases category

Aliases & Classifications for Mononeuropathy

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 61UMLS, 33MeSH, 56SNOMED-CT, 25ICD10
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Summaries for Mononeuropathy

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Wikipedia:64 Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation,... more...

MalaCards based summary: Mononeuropathy, also known as mononeuropathies, is related to endocarditis and neuropathy. An important gene associated with Mononeuropathy is SH3TC2 (SH3 domain and tetratricopeptide repeats 2), and among its related pathways is C-MYB transcription factor network. The compounds steroidal and hydroxychloroquine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, cortex and brain.

Related Diseases for Mononeuropathy

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Diseases related to Mononeuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 135)
idRelated DiseaseScoreTop Affiliating Genes
1endocarditis30.8PRTN3
2neuropathy30.7SH3TC2, PMP22
3polyneuropathy30.5PMP22, IFNA2
4cryoglobulinemia30.4APOH, IFNA2
5mononeuritis multiplex30.2MPO, PRTN3
6churg-strauss syndrome30.2MPO, PRTN3
7hyperthyroidism30.1PRTN3, GAL
8lupus erythematosus30.1IFNA2, APOH
9peritonitis29.9PRTN3, MPO
10vasculitis29.9APOH, IFNA2, MPO, PRTN3
11ulcerative colitis29.7MPO, PRTN3, GAL
12systemic lupus erythematosus29.6APOH, PRTN3, MPO
13eosinophilia29.6IGHE, MPO, PRTN3, IFNA2
14asthma29.5MPO, PRTN3, IGHE
15charcot-marie-tooth disease10.4PMP22
16degos disease10.4APOH
17retinal vasculitis10.4APOH
18bronchiolitis10.4IGHE
19neuronitis10.4
20rhinitis10.4IGHE
21mononeuropathy of the median nerve, mild10.3
22hepatitis10.3
23purpura10.2
24mixed connective tissue disease10.2PRTN3, APOH
25sinusitis10.2PRTN3, IGHE
26diabetic neuropathy10.2
27hepatitis c10.2
28sjogren's syndrome10.2PRTN3, APOH
29hepatitis b10.1
30laryngitis10.1
31mastocytosis10.1IGHE, IFNA2
32rapidly progressive glomerulonephritis10.1PRTN3, MPO
33uveitis10.1IFNA2, GAL
34behcet's disease10.1IFNA2, APOH
35hypersensitivity vasculitis10.1MPO, PRTN3
36hemolytic anemia10.1APOH, IFNA2
37cholangitis, primary sclerosing10.1MPO, PRTN3
38wegener granulomatosis10.1MPO, PRTN3
39cork-handlers' disease10.1PRTN3, MPO
40bronchiectasis10.0MPO, IGHE
41breast cancer10.0
42b-cell lymphomas10.0
43causalgia10.0
44radiculopathy10.0
45cerebritis10.0
46complex regional pain syndrome10.0
47radial neuropathy10.0
48sarcoma10.0
49chronic pain10.0
50carcinoid syndrome10.0IFNA2, GAL

Graphical network of the top 20 diseases related to Mononeuropathy:



Diseases related to mononeuropathy

Symptoms for Mononeuropathy

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Drugs & Therapeutics for Mononeuropathy

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Drug clinical trials:

Search ClinicalTrials for Mononeuropathy

Search NIH Clinical Center for Mononeuropathy

Genetic Tests for Mononeuropathy

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Anatomical Context for Mononeuropathy

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MalaCards organs/tissues related to Mononeuropathy:

31
Spinal cord, Cortex, Brain, Breast, Skin, B cells, Testes, Hypothalamus, Neutrophil

Animal Models for Mononeuropathy or affiliated genes

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Publications for Mononeuropathy

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Articles related to Mononeuropathy:

(show top 50)    (show all 325)
idTitleAuthorsYear
1
Compartment syndrome with mononeuropathies after anterior cruciate ligament reconstruction. (25802956)
2015
2
Nerve biopsy findings contribute to diagnosis of multiple mononeuropathy: 78% of findings support clinical diagnosis. (25788930)
2015
3
Ultrasound diagnosis of peroneal nerve variant in a child with compressive mononeuropathy. (21292098)
2011
4
Mononeuropathy multiplex associated with acute parvovirus B19 infection: characteristics, treatment and outcome. (21287183)
2011
5
Saphenous mononeuropathy after popliteal vein aneurysm repair. (20065798)
2010
6
Activity of new NOP receptor ligands in a rat peripheral mononeuropathy model: potentiation of morphine anti-allodynic activity by NOP receptor antagonists. (19285491)
2009
7
Multiple mononeuropathy following cocaine abuse. (21686808)
2009
8
Development of Churg-Strauss syndrome with severe multiple mononeuropathy after leukotriene receptor antagonist treatment in one of the monozygotic twins with asthma: case report. (19920803)
2009
9
Muscarinic receptor activation potentiates the effect of spinal cord stimulation on pain-related behavior in rats with mononeuropathy. (18343581)
2008
10
Involvement of galanin in nociceptive regulation in the arcuate nucleus of hypothalamus in rats with mononeuropathy. (17383023)
2007
11
Diagnosis and management of "an apparent mechanical" femoral mononeuropathy: a case study. (18060007)
2007
12
A case of mononeuropathy multiplex with type II cryoglobulinemia, necrotizing vasculitis and low grade B cell lymphoma. (17290934)
2007
13
Mononeuropathy following subcutaneous interferon-beta injection. (16511643)
2006
14
Ca2+/calmodulin-dependent protein kinase II in the spinal cord contributes to neuropathic pain in a rat model of mononeuropathy. (15932604)
2005
15
Italian multicentre study of peroneal mononeuropathy at the fibular head: study design and preliminary results. (15830970)
2005
16
Simvastatin-induced mononeuropathy multiplex: case report. (15273860)
2004
17
The effects of aging on thermal hyperalgesia and tactile-evoked allodynia using two models of peripheral mononeuropathy in the rat. (12614905)
2003
18
Electrodiagnostic approach to the patient with suspected mononeuropathy of the upper extremity. (12152443)
2002
19
The active metabolite of leflunomide, an immunosuppressive agent, reduces mechanical sensitivity in a rat mononeuropathy model. (14622739)
2002
20
Proximal median mononeuropathy associated with an anomalous deep course through the brachialis muscle. (11032638)
2000
21
Posterior femoral cutaneous nerve mononeuropathy: a case report. (10943764)
2000
22
Interactions of galanin and morphine in the spinal antinociception in rats with mononeuropathy. (10678779)
2000
23
MRI in unexplained mononeuropathy. (10788751)
2000
24
Spinal cord stimulation attenuates dorsal horn neuronal hyperexcitability in a rat model of mononeuropathy. (10068168)
1999
25
Mononeuropathy multiplex in hemophilia: an electrophysiologic assessment. (9693226)
1998
26
Isolated trigeminal nerve metastases from breast cancer: an unusual cause of trigeminal mononeuropathy. (9586936)
1998
27
Iatrogenic superior gluteal mononeuropathy. (9843087)
1998
28
Successful treatment of painful traumatic mononeuropathy with carbamazepine: insights into a possible molecular pain mechanism. (9395132)
1997
29
A case-control and nerve biopsy study of CREST multiple mononeuropathy. (9409360)
1997
30
Mononeuropathy of a distal branch of the femoral nerve in a body building champion. (9408112)
1997
31
HIV related vasculitic mononeuropathy multiplex: a role for IVIg? (9285470)
1997
32
Complex regional pain syndrome type I (RSD) or peripheral mononeuropathy? A discussion of three cases. (8776555)
1996
33
An unusual presentation of a traumatic ulnar mononeuropathy with a Martin-Gruber anastomosis. (8965853)
1996
34
Mononeuropathy multiplex cranialis in a case of non-Hodgkin's lymphoma mistaken as paraneoplastic syndrome. (9053419)
1995
35
Femoral mononeuropathy induced by the lithotomy position: a report of 5 cases with a review of literature. (8355719)
1993
36
Post-injury treatment with GM1 ganglioside reduces nociceptive behaviors and spinal cord metabolic activity in rats with experimental peripheral mononeuropathy. (1325244)
1992
37
Mononeuropathy multiplex complicating idiopathic thrombocytopenic purpura. (1653915)
1991
38
A model of peripheral mononeuropathy in the rat. (2174143)
1990
39
Immediate improvement of diabetic mononeuropathy after intravenous administration of prostaglandin E1. (2232371)
1990
40
Mononeuropathy associated with hyperthyroidism. (1963442)
1990
41
Outcome of implanted spinal cord stimulation in the treatment of chronic pain: arachnoiditis versus single nerve root injury and mononeuropathy. Brief clinical note. (2520402)
1989
42
A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. (2837713)
1988
43
Compressive mononeuropathy of the deep palmar branch of the ulnar nerve in cyclists. (2851643)
1988
44
Mononeuropathy multiplex (AAEE case report #11). (16758572)
1985
45
Concurrent Bell's palsy and diabetes mellitus: a diabetic mononeuropathy? (7119834)
1982
46
DFP mononeuropathy: evidence for a peripheral site of initiation. (7357425)
1980
47
Diabetic truncal mononeuropathy--a new clinical syndrome. (554781)
1978
48
Mononeuropathy. (184527)
1976
49
Hypertrophic mononeuropathy. (4360401)
1974
50
Ischemic mononeuropathy multiplex associated with diabetes mellitus. (5647941)
1968

Variations for Mononeuropathy

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Expression for genes affiliated with Mononeuropathy

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Search GEO for disease gene expression data for Mononeuropathy.

Pathways for genes affiliated with Mononeuropathy

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Pathways related to Mononeuropathy according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.0PRTN3, MPO

Compounds for genes affiliated with Mononeuropathy

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Compounds related to Mononeuropathy according to GeneCards Suite gene sharing:

(show top 50)    (show all 79)
idCompoundScoreTop Affiliating Genes
1steroidal4410.0GAL, PMP22
2hydroxychloroquine44 1110.9APOH, IFNA2
32-methoxyethanol449.8IFNA2, IGHE
4aopp449.8MPO, APOH
5levamisole44 1110.8IGHE, IFNA2
6salbutamol44 50 28 24 1113.8GAL, IGHE
7procainamide44 1110.8MPO, APOH
8ticlopidine44 1110.7MPO, APOH
9taurine44 60 2411.7GAL, MPO
10allopurinol44 50 1111.7IFNA2, MPO
11dapsone44 1 50 1112.7IFNA2, MPO
128-isoprostane449.6APOH, MPO
13etanercept44 50 1111.6IFNA2, APOH
14budesonide44 50 1111.6IGHE, MPO
15methimazole44 1 1111.6MPO, APOH
16fluticasone propionate44 50 60 1112.6IGHE, MPO
17methanol44 2410.5MPO, APOH
18galactose449.5GAL, APOH, IFNA2
19leucovorin44 50 1111.4GAL, IFNA2
20mitoxantrone44 50 1111.4MPO, IFNA2
21cardiolipin44 1110.4APOH, PRTN3
22epinephrine44 24 1111.4GAL, IGHE, IFNA2
23octreotide44 60 28 1112.4GAL, MPO, IFNA2
245fluorouracil449.3GAL, IFNA2, MPO
25acetylcholine44 50 28 24 1113.2MPO, GAL, IGHE
26phosphatidylserine44 28 1111.2APOH, PRTN3, GAL
27indomethacin44 28 60 1112.1IGHE, IFNA2, MPO
28rituximab44 50 1111.1IFNA2, APOH, PRTN3
29azathioprine44 1 50 1112.1APOH, IFNA2, PRTN3
30arginine449.1APOH, GAL, IGHE, PMP22
31gold449.1PRTN3, APOH, IFNA2
32cytochalasin b449.0PRTN3, MPO
33formaldehyde44 2410.0MPO, PRTN3, GAL
34propylthiouracil44 1 1111.0MPO, PRTN3, APOH
35fmlp449.0PRTN3, GAL, MPO
36iron44 249.9MPO, APOH, IFNA2, GAL
37ascorbic acid44 249.9MPO, IFNA2, PMP22, IGHE
38histamine44 28 2410.8IFNA2, IGHE, MPO, GAL
39prednisolone44 28 1110.8IFNA2, MPO, APOH, IGHE
40cyclophosphamide44 50 1110.8IGHE, IFNA2, MPO, APOH
41vegf448.7IGHE, APOH, MPO, IFNA2
42infliximab44 50 1110.6PRTN3, APOH, IGHE, IFNA2
43alanine448.6IFNA2, PRTN3, IGHE, GAL
44valine448.5APOH, MPO, PRTN3, IFNA2
45superoxide44 249.5IFNA2, PRTN3, MPO, APOH
46oxygen44 249.4MPO, PRTN3, IFNA2, APOH
47nadph44 249.3GAL, PRTN3, MPO
48lipid448.3IFNA2, PRTN3, APOH, GAL
49estrogen448.2IFNA2, PRTN3, IGHE, APOH, GAL
50retinoic acid44 248.7IGHE, MPO, PRTN3, IFNA2, GAL, PMP22

GO Terms for genes affiliated with Mononeuropathy

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Cellular components related to Mononeuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:00301419.4GAL, MPO

Sources for Mononeuropathy

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet