MCID: MRG001
MIFTS: 21

Morgagni Cataract

Categories: Eye diseases

Aliases & Classifications for Morgagni Cataract

MalaCards integrated aliases for Morgagni Cataract:

Name: Morgagni Cataract 12 14
Hypermature Cataract 12
Morgagnian Cataract 69

Classifications:



External Ids:

Disease Ontology 12 DOID:13964
ICD9CM 34 366.18
UMLS 69 C0152258

Summaries for Morgagni Cataract

MalaCards based summary : Morgagni Cataract, also known as hypermature cataract, is related to phacogenic glaucoma and iris disease. An important gene associated with Morgagni Cataract is CRYAA (Crystallin Alpha A), and among its related pathways/superpathways are Selenium Micronutrient Network and TP53 Regulates Metabolic Genes. Affiliated tissues include eye.

Related Diseases for Morgagni Cataract

Diseases related to Morgagni Cataract via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 phacogenic glaucoma 10.2 CRYAA PHEX
2 iris disease 10.1 CRYAA PHEX
3 senile cataract 10.0 CRYAA GSR
4 cataract 10.0
5 lens disease 9.9 CRYAA PHEX

Comorbidity relations with Morgagni Cataract via Phenotypic Disease Network (PDN):


Phacolytic Glaucoma

Graphical network of the top 20 diseases related to Morgagni Cataract:



Diseases related to Morgagni Cataract

Symptoms & Phenotypes for Morgagni Cataract

Drugs & Therapeutics for Morgagni Cataract

Search Clinical Trials , NIH Clinical Center for Morgagni Cataract

Genetic Tests for Morgagni Cataract

Anatomical Context for Morgagni Cataract

MalaCards organs/tissues related to Morgagni Cataract:

38
Eye

Publications for Morgagni Cataract

Articles related to Morgagni Cataract:

# Title Authors Year
1
Study of the substructure of the Morgagni and Brunescens cataract with the TAO non-coating technique. Part 1: Morgagni cataract. ( 1305020 )
1992
2
A modified erisophake. Extraction of a hypermature (Morgagni) cataract. ( 13903577 )
1962

Variations for Morgagni Cataract

Expression for Morgagni Cataract

Search GEO for disease gene expression data for Morgagni Cataract.

Pathways for Morgagni Cataract

GO Terms for Morgagni Cataract

Biological processes related to Morgagni Cataract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.62 GAPDH GSR PRDX5 TXN
2 movement of cell or subcellular component GO:0006928 9.37 CALD1 TXN
3 cellular response to oxidative stress GO:0034599 9.33 GSR PRDX5 TXN
4 nucleobase-containing small molecule interconversion GO:0015949 9.26 GSR TXN
5 cellular oxidant detoxification GO:0098869 9.13 GSR PRDX5 TXN
6 cell redox homeostasis GO:0045454 8.8 GSR PRDX5 TXN

Molecular functions related to Morgagni Cataract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADP binding GO:0050661 8.62 GAPDH GSR

Sources for Morgagni Cataract

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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