MCID: MRG001
MIFTS: 20

Morgagni Cataract malady

Categories: Eye diseases

Aliases & Classifications for Morgagni Cataract

Aliases & Descriptions for Morgagni Cataract:

Name: Morgagni Cataract 12 14
Hypermature Cataract 12
Morgagnian Cataract 69

Classifications:



External Ids:

Disease Ontology 12 DOID:13964
ICD9CM 35 366.18
UMLS 69 C0152258

Summaries for Morgagni Cataract

MalaCards based summary : Morgagni Cataract, also known as hypermature cataract, is related to mechanical strabismus and pseudopterygium. An important gene associated with Morgagni Cataract is CRYAA (Crystallin Alpha A), and among its related pathways/superpathways are Folate Metabolism and TP53 Regulates Metabolic Genes. Affiliated tissues include eye.

Related Diseases for Morgagni Cataract

Diseases related to Morgagni Cataract via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 mechanical strabismus 10.1 CRYAA PHEX
2 pseudopterygium 10.1 CRYAA PHEX
3 olecranon bursitis 10.1 CRYAA PHEX
4 tenosynovitis 10.0 CRYAA GSR
5 cataract 9.9
6 peptic esophagitis 8.6 CALD1 CBARP CRYAA GAPDH GSR HHEX

Comorbidity relations with Morgagni Cataract via Phenotypic Disease Network (PDN):


Phacolytic Glaucoma

Graphical network of the top 20 diseases related to Morgagni Cataract:



Diseases related to Morgagni Cataract

Symptoms & Phenotypes for Morgagni Cataract

Drugs & Therapeutics for Morgagni Cataract

Search Clinical Trials , NIH Clinical Center for Morgagni Cataract

Genetic Tests for Morgagni Cataract

Anatomical Context for Morgagni Cataract

MalaCards organs/tissues related to Morgagni Cataract:

39
Eye

Publications for Morgagni Cataract

Articles related to Morgagni Cataract:

id Title Authors Year
1
Study of the substructure of the Morgagni and Brunescens cataract with the TAO non-coating technique. Part 1: Morgagni cataract. ( 1305020 )
1992
2
A modified erisophake. Extraction of a hypermature (Morgagni) cataract. ( 13903577 )
1962

Variations for Morgagni Cataract

Expression for Morgagni Cataract

Search GEO for disease gene expression data for Morgagni Cataract.

Pathways for Morgagni Cataract

Pathways related to Morgagni Cataract according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.77 GSR PRDX5 TXN
2 11.06 GSR PRDX5 TXN
3 10.55 GSR TXN
4
Show member pathways
10.54 GSR PRDX5 TXN

GO Terms for Morgagni Cataract

Biological processes related to Morgagni Cataract according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.62 GAPDH GSR PRDX5 TXN
2 movement of cell or subcellular component GO:0006928 9.37 CALD1 TXN
3 cellular response to oxidative stress GO:0034599 9.33 GSR PRDX5 TXN
4 nucleobase-containing small molecule interconversion GO:0015949 9.26 GSR TXN
5 cell redox homeostasis GO:0045454 9.13 GSR PRDX5 TXN
6 cellular oxidant detoxification GO:0098869 8.8 GSR PRDX5 TXN

Molecular functions related to Morgagni Cataract according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 NADP binding GO:0050661 8.62 GAPDH GSR

Sources for Morgagni Cataract

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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