MCID: MRN004
MIFTS: 18

Morning Glory Disc Anomaly malady

Summaries for Morning Glory Disc Anomaly

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Sources:
66Wikipedia, 48OMIM, 34MalaCards
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Wikipedia:66 The morning glory disc anomaly (MGDA) is a congenital deformity resulting from failure of the optic... more...

MalaCards: Morning Glory Disc Anomaly is related to coloboma and retinitis. An important gene associated with Morning Glory Disc Anomaly is PAX6 (paired box 6). Affiliated tissues include eye and pituitary.

Description from OMIM:48 120430

Aliases & Classifications for Morning Glory Disc Anomaly

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48OMIM
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Aliases & Descriptions:

morning glory disc anomaly 48


Related Diseases for Morning Glory Disc Anomaly

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18GeneCards, 19GeneDecks
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Diseases related to Morning Glory Disc Anomaly via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1coloboma10.6
2retinitis10.6
3neurofibromatosis10.4
4aniridia10.4
5optic nerve glioma10.4

Graphical network of diseases related to Morning Glory Disc Anomaly:



Diseases related to morning glory disc anomaly

Symptoms for Morning Glory Disc Anomaly

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48OMIM
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Symptoms by clinical synopsis from OMIM:

120430

Clinical features from OMIM:

120430

Drugs & Therapeutics for Morning Glory Disc Anomaly

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Genetic Tests for Morning Glory Disc Anomaly

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Anatomical Context for Morning Glory Disc Anomaly

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34MalaCards
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MalaCards organs/tissues related to Morning Glory Disc Anomaly:

34
Eye, Pituitary

Animal Models for Morning Glory Disc Anomaly or affiliated genes

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Publications for Morning Glory Disc Anomaly

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53PubMed
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Articles related to Morning Glory Disc Anomaly:

(show all 30)
idTitleAuthorsYear
1
Morning glory disc anomaly: characteristic MR imaging findings. (23660287)
2013
2
Contractile peripapillary staphyloma mimicking morning-glory disc anomaly. (22531311)
2012
3
Optic nerve head drusen in an eye with morning glory disc anomaly. (21805072)
2012
4
Morning glory disc anomaly and optic nerve coloboma. (21622684)
2012
5
Morning glory disc anomaly with contractile movements. (22865260)
2012
6
Morning glory disc anomaly with peripheral retinal nonperfusion in 4 consecutive cases. (23044951)
2012
7
Morning glory disc anomaly in association with ipsilateral optic nerve glioma. (22893090)
2012
8
Optic disc contractility in morning glory disc anomaly. (21323306)
2011
9
Mid line craniofacial defects and morning glory disc anomaly with clinical anophthalmos-a distinct clinical entity. (20302414)
2010
10
Update on the morning glory disc anomaly. (18484308)
2008
11
Pituitary stalk duplication in association with moya moya disease and bilateral morning glory disc anomaly - broadening the clinical spectrum of midline defects. (18350354)
2008
12
The morning glory disc anomaly. (18546928)
2008
13
Optical coherence tomographic characteristics in morning glory disc anomaly. (17392858)
2007
14
Chiari type capital I, Ukrainian malformation associated with morning glory disc anomaly. (17204923)
2006
15
Reversible carotid artery narrowing in morning glory disc anomaly. (16148627)
2005
16
Morning glory disc anomaly, midline cranial defects and abnormal carotid circulation: an association worth looking for. (15480611)
2005
17
Morning glory disc anomaly: an atypical case. (12598458)
2003
18
Bilateral morning glory disc anomaly. (12831152)
2003
19
Morning glory disc anomaly in neurofibromatosis type 2. (10369605)
1999
20
Capillary haemangiomas in association with morning glory disc anomaly. (9826051)
1998
21
Morning glory disc anomaly and moyamoya vessels. (9488287)
1998
22
Midline craniofacial defects and morning glory disc anomaly. A distinct clinical entity. (8741108)
1996
23
Retinal arteriovenous communications in the morning glory disc anomaly. (7654274)
1995
24
Morning glory disc anomaly or optic disc coloboma? (8311757)
1994
25
Morning glory disc anomaly or optic disc coloboma? (8311756)
1994
26
Trisomy 4q with morning glory disc anomaly. (2377355)
1990
27
The morning glory disc anomaly: contractile movement, classification, and embryogenesis. (3319466)
1987
28
Morning glory disc anomaly with pulsating peripapillary staphyloma. A case history. (3425268)
1987
29
Aniridia, atypical iris defects, optic pit and the morning glory disc anomaly in a family. (3097598)
1986
30
Persistence of the primary vitreous in association with the morning glory disc anomaly. (6707857)
1984

Variations for Morning Glory Disc Anomaly

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1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Morning Glory Disc Anomaly:

1
id Gene Name Type Significance SNP ID Assembly Location
1PAX6NM_000280.4(PAX6): c.202C> T (p.Pro68Ser)single nucleotide variantPathogenicrs121907923GRCh37Chr 11, 31823264: 31823264

Expression for genes affiliated with Morning Glory Disc Anomaly

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Morning Glory Disc Anomaly

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Pathways for genes affiliated with Morning Glory Disc Anomaly

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Compounds for genes affiliated with Morning Glory Disc Anomaly

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GO Terms for genes affiliated with Morning Glory Disc Anomaly

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Products for genes affiliated with Morning Glory Disc Anomaly

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Morning Glory Disc Anomaly

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet