MCID: MRP002
MIFTS: 27

Morpheaform Basal Cell Carcinoma malady

Categories: Cancer diseases

Aliases & Classifications for Morpheaform Basal Cell Carcinoma

Aliases & Descriptions for Morpheaform Basal Cell Carcinoma:

Name: Morpheaform Basal Cell Carcinoma 12 14
Morphea-Type Basal Cell Carcinoma 12
Cicatricial Basal-Cell Carcinoma 12
Basal Cell Carcinoma, Morphea 12
Morpheic Basal Cell Carcinoma 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4292
NCIt 47 C27182
UMLS 69 C0555191

Summaries for Morpheaform Basal Cell Carcinoma

MalaCards based summary : Morpheaform Basal Cell Carcinoma, also known as morphea-type basal cell carcinoma, is related to basal cell carcinoma and anal margin carcinoma. An important gene associated with Morpheaform Basal Cell Carcinoma is PHLDA1 (Pleckstrin Homology Like Domain Family A Member 1), and among its related pathways/superpathways are Developmental Biology and Cytoskeletal Signaling.

Related Diseases for Morpheaform Basal Cell Carcinoma

Diseases related to Morpheaform Basal Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 46)
id Related Disease Score Top Affiliating Genes
1 basal cell carcinoma 10.5
2 anal margin carcinoma 10.2 KRT15 KRT17
3 neurofibrosarcoma 10.2 KRT17 KRT20
4 pelvic inflammatory disease 10.2 KRT17 KRT20
5 colon signet ring adenocarcinoma 10.1 AR KRT20
6 acute stress disorder 10.1 KRT17 KRT20
7 angiolipomatosis, familial 10.1 AR KRT20
8 lateral sinus thrombosis 10.1 KRT17 KRT19
9 distal arthrogryposis 10.1 KRT17 KRT19
10 papillary adenofibroma 10.1 KRT19 KRT20
11 sensory organ benign neoplasm 10.1 KRT19 KRT20
12 rectum lymphoma 10.1 KRT19 KRT20
13 gastritis 10.1 CDH1 KRT20
14 ovarian squamous cell carcinoma 10.1 CDH1 KRT20
15 bowman's membrane folds or rupture 10.1 AR KRT19
16 granulocytopenia 10.1 CDH1 KRT20
17 familial renal oncocytoma 10.1 CDH1 KRT20
18 prostate stromal sarcoma 10.1 AR KRT20
19 mitochondrial encephalomyopathy 10.1 KRT17 KRT20
20 embryonal testis carcinoma 10.1 CDH1 KRT20
21 anal margin basal cell carcinoma 10.1 KRT17 KRT20 PHLDA1
22 gallbladder signet ring cell adenocarcinoma 10.1 CDH1 KRT20
23 pancreatic gastrinoma 10.0 KRT15 KRT17 KRT20
24 estrogen-receptor positive breast cancer 10.0 CDH1 KRT17
25 small intestine leiomyoma 10.0 KRT15 KRT17 KRT20
26 myotonic disease 10.0 CDH1 KRT20
27 advanced sleep phase syndrome 10.0 CDH1 KRT20
28 pyomyositis 10.0 CDH1 KRT17
29 alpha chain disease 10.0 KRT15 KRT20
30 vulva adenocarcinoma 10.0 AR KRT15 KRT20
31 basophilic carcinoma 10.0 CDH1 KRT19
32 papillary transitional carcinoma 10.0 CDH1 KRT20
33 angiosarcoma 9.9
34 peritoneal serous papillary adenocarcinoma 9.9 CDH1 KRT19
35 ornithinemia 9.9 CDH1 KRT19
36 pituitary carcinoma 9.9 CDH1 KRT19 KRT20
37 odontotrichoungual-digital-palmar syndrome 9.9 CDH1 KRT19 KRT20
38 tenosynovitis of foot and ankle 9.9 CDH1 KRT19 KRT20
39 gastroesophageal junction adenocarcinoma 9.9 CDH1 KRT19 KRT20
40 malignant pleural solitary fibrous tumor 9.9 CDH1 KRT19 KRT20
41 placenta praevia 9.9 CDH1 KRT19 KRT20
42 ladd syndrome 9.9 CDH1 KRT19 KRT20
43 orchitis 9.8 KRT15 KRT17 KRT19 KRT20
44 oral squamous cell carcinoma 9.8 CDH1 KRT20
45 sarcomatoid basal cell carcinoma 9.3 AR CDH1 DAND5 KRT15 KRT17 KRT20
46 infiltrative basal cell carcinoma 8.9 AR CDH1 DAND5 KRT15 KRT17 KRT19

Graphical network of the top 20 diseases related to Morpheaform Basal Cell Carcinoma:



Diseases related to Morpheaform Basal Cell Carcinoma

Symptoms & Phenotypes for Morpheaform Basal Cell Carcinoma

Drugs & Therapeutics for Morpheaform Basal Cell Carcinoma

Interventional clinical trials:


id Name Status NCT ID Phase
1 Study Evaluating the Efficacy of Oral Vismodegib in Various Histologic Subtypes Recruiting NCT01700049 Phase 2
2 Mohs Versus Traditional Surgery - Basal-Cell Carcinomas (BCC) Unknown status NCT00699829
3 Recurrence Rate and Esthetic Outcome After Excision of Basal Cell Carcinomas Excluded From Trial NCT00515970 Unknown status NCT00639652

Search NIH Clinical Center for Morpheaform Basal Cell Carcinoma

Genetic Tests for Morpheaform Basal Cell Carcinoma

Anatomical Context for Morpheaform Basal Cell Carcinoma

Publications for Morpheaform Basal Cell Carcinoma

Articles related to Morpheaform Basal Cell Carcinoma:

(show all 12)
id Title Authors Year
1
Morpheaform Basal Cell Carcinomas With Areas of Predominantly Single-Cell Pattern of Infiltration: Diagnostic Utility of p63 and Cytokeratin. ( 27043336 )
2016
2
Fluorouracil and Other Predictors of Morpheaform Basal Cell Carcinoma Among High-Risk Patients: The Veterans Affairs Topical Tretinoin Chemoprevention Trial. ( 24258386 )
2013
3
The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers. ( 23398472 )
2013
4
Diagnostic utility of cytokeratin 17 immunostaining in morpheaform basal cell carcinoma and for facilitating the detection of tumor cells at the surgical margins. ( 22691048 )
2012
5
Commentary: diagnostic utility of cytokeratin 17 immunostaining in morpheaform basal cell carcinoma and for facilitating the detection of tumor cells at the surgical margins. ( 22861061 )
2012
6
Photodynamic therapy as adjunctive therapy for morpheaform basal cell carcinoma. ( 21879201 )
2011
7
Angiosarcoma clinically resembling morpheaform basal cell carcinoma. ( 18637812 )
2008
8
Morpheaform basal cell carcinoma in African Americans. ( 15606838 )
2004
9
Can smoking and/or occupational UV exposure have any role in the development of the morpheaform basal cell carcinoma? A critical role for peritumoral mast cells. ( 12100702 )
2002
10
Analysis of morpheaform basal cell carcinoma. ( 3220994 )
1988
11
Morpheaform basal cell carcinoma in a young black woman. ( 3343426 )
1988
12
Morpheaform basal cell carcinoma. ( 5676900 )
1968

Variations for Morpheaform Basal Cell Carcinoma

Expression for Morpheaform Basal Cell Carcinoma

Search GEO for disease gene expression data for Morpheaform Basal Cell Carcinoma.

Pathways for Morpheaform Basal Cell Carcinoma

Pathways related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.77 DAND5 KRT15 KRT17 KRT19 KRT20
2 11.74 CDH1 KRT17 KRT19 KRT20
3
Show member pathways
11.38 KRT15 KRT17 KRT19 KRT20
4 11.15 AR CDH1

GO Terms for Morpheaform Basal Cell Carcinoma

Cellular components related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.96 KRT17 KRT19
2 intermediate filament GO:0005882 8.92 KRT15 KRT17 KRT19 KRT20

Biological processes related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.26 KRT15 KRT17 KRT19 KRT20
2 intermediate filament organization GO:0045109 9.16 KRT17 KRT20
3 cornification GO:0070268 8.92 KRT15 KRT17 KRT19 KRT20

Molecular functions related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 beta-catenin binding GO:0008013 8.96 AR CDH1
2 structural constituent of cytoskeleton GO:0005200 8.92 KRT15 KRT17 KRT19 KRT20

Sources for Morpheaform Basal Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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