HSMN
MCID: MTR007
MIFTS: 27

Motor Peripheral Neuropathy (HSMN) malady

Neuronal diseases, Muscle diseases categories

Summaries for Motor Peripheral Neuropathy

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34MalaCards
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MalaCards: Motor Peripheral Neuropathy, also known as hsmn - hereditary sensory and motor neuropathy, is related to motor neuritis and charcot-marie-tooth disease. An important gene associated with Motor Peripheral Neuropathy is NDRG3 (NDRG family member 3), and among its related pathways are Apoptosis and Autophagy and Angiogenesis.

Aliases & Classifications for Motor Peripheral Neuropathy

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9Disease Ontology, 46Novoseek, 63UMLS, 36MeSH, 41NCIt, 59SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Muscle diseases


Aliases & Descriptions:

motor peripheral neuropathy 9
hsmn - hereditary sensory and motor neuropathy 9
hereditary motor and sensory neuropathies 63
hereditary motor and sensory neuropathy 9
hereditary sensory motor neuropathy 46
neuropathic muscular atrophy 9
peripheral motor neuropathy 63
hsmn 9


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Disease Ontology9 DOID:2477
MeSH36 D015417
NCIt41 C75467

Related Diseases for Motor Peripheral Neuropathy

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18GeneCards, 19GeneDecks
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Diseases related to Motor Peripheral Neuropathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 125)
idRelated DiseaseScoreTop Affiliating Genes
1motor neuritis30.1NDRG4, NDRG3
2charcot-marie-tooth disease10.9
3hereditary motor and sensory neuropathy with agenesis of the corpus callosum10.8
4hereditary motor and sensory neuropathy vi10.7
5optic atrophy10.7
6tooth disease10.7
7charcot-marie-tooth disease with pyramidal features, autosomal dominant10.7
8sensory neuropathy type 110.7
9charcot-marie-tooth disease type 2c10.7
10neuropathy, hereditary motor and sensory, okinawa type10.7
11charcot-marie-tooth disease type 110.6
12neuropathy, hereditary motor and sensory, russe type10.6
13charcot-marie-tooth disease type 310.5
14paraplegia10.5
15charcot-marie-tooth disease type 1a10.5
16neuropathy, hereditary motor and sensory, lom type10.5
17spasticity10.5
18charcot-marie-tooth disease, dominant intermediate b10.5
19neuropathy10.5
20peripheral neuropathy10.5
21glaucoma10.5
22hereditary neuropathy with liability to pressure palsies10.5
23charcot-marie-tooth neuropathy type 4a10.5
24charcot-marie-tooth disease type 1b10.5
25charcot-marie-tooth disease type 1d10.5
26charcot-marie-tooth disease type 2b10.5
27charcot-marie-tooth disease type 2b110.5
28charcot-marie-tooth disease type 2b210.5
29charcot-marie-tooth disease type 2h10.5
30charcot-marie-tooth disease type 4b210.5
31charcot-marie-tooth disease x-linked 110.5
32cowchock syndrome10.5
33charcot-marie-tooth neuropathy type 2c10.5
34hereditary neuropathies10.5
35charcot-marie-tooth disease, type 2a110.5
36charcot-marie-tooth disease, type 2a210.5
37giant axonal neuropathy 2, autosomal dominant10.5
38autosomal dominant charcot-marie-tooth disease type 210.5
39charcot-marie-tooth disease - deafness - intellectual disability10.5
40axonal neuropathy10.3
41juvenile glaucoma10.3
42neuronitis10.3
43lambert-eaton myasthenic syndrome10.3
44charcot-marie-tooth disease type 410.3
45superior mesenteric artery syndrome10.3
46demyelinating polyneuropathy10.3
47gonadal dysgenesis10.3
48hereditary sensory neuropathy10.3
49multiple sclerosis10.3
50myotonic dystrophy10.3

Graphical network of the top 20 diseases related to Motor Peripheral Neuropathy:



Diseases related to motor peripheral neuropathy

Symptoms for Motor Peripheral Neuropathy

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Drugs & Therapeutics for Motor Peripheral Neuropathy

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Motor Peripheral Neuropathy

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Anatomical Context for Motor Peripheral Neuropathy

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Animal Models for Motor Peripheral Neuropathy or affiliated genes

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Publications for Motor Peripheral Neuropathy

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53PubMed
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Articles related to Motor Peripheral Neuropathy:

idTitleAuthorsYear
1
Both Schwann cell and axonal defects cause motor peripheral neuropathy in Ebf2-/- mice. (21220016)
2011
2
Paraneoplastic encephalomyelitis/sensory motor peripheral neuropathy - an autopsy case study. (16012914)
2005
3
Dapsone-induced motor peripheral neuropathy in pemphigus foliaceus. (8565254)
1995
4
Sensory and motor peripheral neuropathy in olivopontocerebellar atrophy. (3014798)
1986
5
Hereditary motor peripheral neuropathy predominantly affecting the arms. (180264)
1976

Variations for Motor Peripheral Neuropathy

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Expression for genes affiliated with Motor Peripheral Neuropathy

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Motor Peripheral Neuropathy

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Pathways for genes affiliated with Motor Peripheral Neuropathy

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51PathCards, 5Cell Signaling Technology
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Pathways related to Motor Peripheral Neuropathy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1NDRG4, NDRG3
29.1NDRG4, NDRG3
39.1NDRG4, NDRG3

Compounds for genes affiliated with Motor Peripheral Neuropathy

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GO Terms for genes affiliated with Motor Peripheral Neuropathy

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17Gene Ontology
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Biological processes related to Motor Peripheral Neuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell differentiationGO:0301549.1NDRG4, NDRG3

Products for genes affiliated with Motor Peripheral Neuropathy

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Sources for Motor Peripheral Neuropathy

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet