HSMN
MCID: MTR007
MIFTS: 27

Motor Peripheral Neuropathy (HSMN) malady

Neuronal diseases, Muscle diseases categories
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Summaries for Motor Peripheral Neuropathy

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MalaCards based summary: Motor Peripheral Neuropathy, also known as hsmn - hereditary sensory and motor neuropathy, is related to motor neuritis and charcot-marie-tooth disease. An important gene associated with Motor Peripheral Neuropathy is NDRG3 (NDRG family member 3), and among its related pathways are Apoptosis and Autophagy and Angiogenesis.

Aliases & Classifications for Motor Peripheral Neuropathy

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Sources:
8Disease Ontology, 44Novoseek, 62UMLS, 57SNOMED-CT, 34MeSH, 39NCIt
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Motor Peripheral Neuropathy, Aliases & Descriptions:

Name: Motor Peripheral Neuropathy 8
Hsmn - Hereditary Sensory and Motor Neuropathy 8
Hereditary Motor and Sensory Neuropathies 62
Hereditary Motor and Sensory Neuropathy 8
 
Hereditary Sensory Motor Neuropathy 44
Neuropathic Muscular Atrophy 8
Peripheral Motor Neuropathy 62
Hsmn 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Muscle diseases


External Ids:

Disease Ontology8 DOID:2477
MeSH34 D015417
NCIt39 C75467

Related Diseases for Motor Peripheral Neuropathy

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Diseases related to Motor Peripheral Neuropathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 114)
idRelated DiseaseScoreTop Affiliating Genes
1motor neuritis30.3NDRG4, NDRG3
2charcot-marie-tooth disease10.9
3hereditary motor and sensory neuropathy with agenesis of the corpus callosum10.8
4charcot-marie-tooth disease with pyramidal features, autosomal dominant10.7
5hereditary motor and sensory neuropathy vi10.7
6optic atrophy10.7
7charcot-marie-tooth disease type 2c10.7
8sensory neuropathy type 110.7
9tooth disease10.7
10neuropathy, hereditary motor and sensory, okinawa type10.7
11agenesis of the corpus callosum10.6
12neuropathy, hereditary motor and sensory, russe type10.6
13charcot-marie-tooth disease type 310.6
14refsum disease10.6
15paraplegia10.6
16charcot-marie-tooth disease type 1a10.6
17charcot-marie-tooth disease type 1b10.6
18neuropathy, hereditary motor and sensory, lom type10.6
19spasticity10.6
20charcot-marie-tooth disease, dominant intermediate b10.6
21neuropathy10.5
22peripheral neuropathy10.5
23hereditary spastic paraplegia10.5
24charcot-marie-tooth disease type 110.5
25hereditary neuropathy with liability to pressure palsies10.5
26charcot-marie-tooth neuropathy type 4a10.5
27charcot-marie-tooth disease type 1d10.5
28charcot-marie-tooth disease type 2b10.5
29charcot-marie-tooth disease type 2b110.5
30charcot-marie-tooth disease type 2b210.5
31charcot-marie-tooth disease type 2h10.5
32charcot-marie-tooth disease type 4b210.5
33charcot-marie-tooth disease x-linked 110.5
34hypertrophic neuropathy of dejerine-sottas10.5
35hereditary neuropathies10.5
36charcot-marie-tooth disease, type 2a110.5
37charcot-marie-tooth disease, type 2a210.5
38giant axonal neuropathy 2, autosomal dominant10.5
39charcot-marie-tooth disease - deafness - intellectual disability10.5
40chronic inflammatory demyelinating polyneuropathy10.3
41multiple sclerosis10.3
42axonal neuropathy10.3
43juvenile glaucoma10.3
44lambert-eaton myasthenic syndrome10.3
45charcot-marie-tooth disease type 210.3
46charcot-marie-tooth disease type x10.3
47charcot-marie-tooth disease type 410.3
48neuronitis10.3
49superior mesenteric artery syndrome10.3
50demyelinating polyneuropathy10.3

Graphical network of the top 20 diseases related to Motor Peripheral Neuropathy:



Diseases related to motor peripheral neuropathy

Symptoms for Motor Peripheral Neuropathy

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Drugs & Therapeutics for Motor Peripheral Neuropathy

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Drug clinical trials:

Search ClinicalTrials for Motor Peripheral Neuropathy

Search NIH Clinical Center for Motor Peripheral Neuropathy

Genetic Tests for Motor Peripheral Neuropathy

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Anatomical Context for Motor Peripheral Neuropathy

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Animal Models for Motor Peripheral Neuropathy or affiliated genes

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Publications for Motor Peripheral Neuropathy

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Articles related to Motor Peripheral Neuropathy:

idTitleAuthorsYear
1
Both Schwann cell and axonal defects cause motor peripheral neuropathy in Ebf2-/- mice. (21220016)
2011
2
Paraneoplastic encephalomyelitis/sensory motor peripheral neuropathy - an autopsy case study. (16012914)
2005
3
Dapsone-induced motor peripheral neuropathy in pemphigus foliaceus. (8565254)
1995
4
Sensory and motor peripheral neuropathy in olivopontocerebellar atrophy. (3014798)
1986
5
Hereditary motor peripheral neuropathy predominantly affecting the arms. (180264)
1976

Variations for Motor Peripheral Neuropathy

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Expression for genes affiliated with Motor Peripheral Neuropathy

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Expression patterns in normal tissues for genes affiliated with Motor Peripheral Neuropathy

Search GEO for disease gene expression data for Motor Peripheral Neuropathy.

Pathways for genes affiliated with Motor Peripheral Neuropathy

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Pathways related to Motor Peripheral Neuropathy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1NDRG4, NDRG3
29.1NDRG4, NDRG3
39.1NDRG4, NDRG3

Compounds for genes affiliated with Motor Peripheral Neuropathy

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GO Terms for genes affiliated with Motor Peripheral Neuropathy

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Biological processes related to Motor Peripheral Neuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell differentiationGO:0301549.1NDRG4, NDRG3

Products for genes affiliated with Motor Peripheral Neuropathy

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  • Antibodies
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Sources for Motor Peripheral Neuropathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet