MCID: MCN001
MIFTS: 45

Mucinous Adenocarcinoma malady

Cancer diseases category

Summaries for Mucinous Adenocarcinoma

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Disease Ontology:9 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, which produce mucin.

MalaCards based summary: Mucinous Adenocarcinoma, also known as mucin-producing adenocarcinoma, is related to pseudomyxoma peritonei and adenocarcinoma in situ. An important gene associated with Mucinous Adenocarcinoma is AMACR (alpha-methylacyl-CoA racemase), and among its related pathways are O-linked glycosylation of mucins and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. The compounds deoxycholic acid and deoxyribonucleic acid have been mentioned in the context of this disorder. Affiliated tissues include prostate, colon and appendix, and related mouse phenotypes are tumorigenesis and digestive/alimentary.

Aliases & Classifications for Mucinous Adenocarcinoma

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Mucinous Adenocarcinoma, Aliases & Descriptions:

Name: Mucinous Adenocarcinoma 9 11 60
Mucin-Producing Adenocarcinoma 9 60
Pseudomyxoma Peritonei with Unknown Primary Site 9
 
Mucin-Secreting Adenocarcinoma 9
Mucin-Secreting Carcinoma 9
Mucous Carcinoma 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology9 DOID:3030
MeSH33 D002288
SNOMED-CT55 72495009, 900006
NCIt38 C26712

Related Diseases for Mucinous Adenocarcinoma

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Diseases related to Mucinous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 171)
idRelated DiseaseScoreTop Affiliating Genes
1pseudomyxoma peritonei31.4CDX2, MUC2
2adenocarcinoma in situ31.1CDKN2A
3adenocarcinoma30.9AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
4nephrogenic adenoma30.8AMACR
5cystadenocarcinoma30.7MUC1, MUC2
6gallbladder cancer30.3MUC2, CDX2
7colorectal cancer30.3AMACR, MUC2, CDX2
8endometrial cancer30.3CDKN2A, CDX2, MUC1
9mucoepidermoid carcinoma30.2MUC2, MUC1
10adenoma30.1AMACR, MUC2, MUC1, CDX2, CDKN2A
11mesothelioma30.0CDKN2A, MUC1, VIM
12prostatitis10.8
13mucinous adenocarcinoma of the appendix10.8
14ovarian mucinous adenocarcinoma10.6
15teratoma10.6
16colon mucinous adenocarcinoma10.5
17endometrial mucinous adenocarcinoma10.5
18renal cell carcinoma10.5AMACR
19colitis10.5
20peritonitis10.5
21biliary papillomatosis10.4MUC2
22endocervicitis10.4
23cystic teratoma10.4
24mucinous adenocarcinoma of ovary10.4
25crohn's disease10.4
26eccrine porocarcinoma10.4MUC1
27hidradenoma10.4MUC1
28syringoma10.4MUC1
29anal fistula10.3
30villous adenoma10.3
31intestinal variant cervical mucinous adenocarcinoma10.3
32villoglandular variant cervical mucinous adenocarcinoma10.3
33endocervical type cervical mucinous adenocarcinoma10.3
34signet ring cell variant cervical mucinous adenocarcinoma10.3
35uterine ligament mucinous adenocarcinoma10.3
36bile duct mucinous adenocarcinoma10.3
37ampulla of vater mucinous adenocarcinoma10.3
38fallopian tube mucinous adenocarcinoma10.3
39rectum mucinous adenocarcinoma10.3
40appendix adenocarcinoma10.3
41cervical mucinous adenocarcinoma10.3
42adenomatoid tumor10.3VIM
43ulcerative colitis10.3
44neuroendocrine carcinoma10.3
45large cell neuroendocrine carcinoma10.3
46intussusception10.3
47thyroiditis10.3
48urachal cyst10.3
49glomus tumor10.3VIM
50microinvasive gastric cancer10.2MUC2, CDX2

Graphical network of the top 20 diseases related to Mucinous Adenocarcinoma:



Diseases related to mucinous adenocarcinoma

Symptoms for Mucinous Adenocarcinoma

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Drugs & Therapeutics for Mucinous Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Mucinous Adenocarcinoma

Search NIH Clinical Center for Mucinous Adenocarcinoma

Genetic Tests for Mucinous Adenocarcinoma

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Anatomical Context for Mucinous Adenocarcinoma

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MalaCards organs/tissues related to Mucinous Adenocarcinoma:

31
Prostate, Colon, Appendix, Ovary, Lung, Pancreas, Cervix, Salivary gland, Kidney, Breast, Eye, Thymus, Liver, Thyroid, Lymph node, Skin, Testis, Brain, Heart, Small intestine, Uterus, Placenta, T cells, Tongue, Trachea

Animal Models for Mucinous Adenocarcinoma or affiliated genes

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MGI Mouse Phenotypes related to Mucinous Adenocarcinoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.4MUC2, MUC1, CDX2, CDKN2A
2MP:00053818.4CDKN2A, CDX2, MUC1, MUC2
3MP:00053798.1MUC2, MUC1, CDX2, CDKN2A
4MP:00107687.7CDKN2A, CDX2, MUC2, VIM, AMACR
5MP:00053787.6AMACR, VIM, MUC2, CDX2, CDKN2A
6MP:00053767.2CDKN2A, CDX2, MUC1, MUC2, VIM, AMACR

Publications for Mucinous Adenocarcinoma

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Articles related to Mucinous Adenocarcinoma:

(show top 50)    (show all 474)
idTitleAuthorsYear
1
Mixed carcinoid-mucinous adenocarcinoma arising in mature teratoma of mesentery. (25812659)
2015
2
The "drunken honeycomb" feature of pulmonary mucinous adenocarcinoma: a diagnostic pitfall of bronchial brushing cytology. (21563323)
2013
3
HNF4I+ as a marker for invasive mucinous adenocarcinoma of the lung. (23108025)
2013
4
Metastatic appendiceal goblet cell carcinoid masquerading as mucinous adenocarcinoma in effusion cytology: A diagnostic pitfall. (23833405)
2013
5
Bilateral breast metastasis from mucinous adenocarcinoma of the rectum: a case report and review of the literature. (24022315)
2013
6
Endobronchial ultrasound-guided transbronchial needle aspiration diagnosis of mediastinal lymph node metastasis of mucinous adenocarcinoma: arborizing stromal meshwork fragments as a diagnostic clue. (22298306)
2013
7
Mucinous adenocarcinoma arising from diffuse serrated adenoma of the appendix which mimics appendicular abscess. (23012662)
2012
8
Unusual isolated perineal recurrence in mucinous adenocarcinoma of the rectum after abdominoperineal resection: usefulness of dual-time-point FDG PET in evaluating mucinous tumors. (22955074)
2012
9
Mucinous adenocarcinoma of the intestinal type arising from mature cystic teratoma of the ovary: a rare case report and review of the literature. (23216975)
2012
10
A rare case of mucinous adenocarcinoma of the colon presenting as ileoileal intussusception in an adult. (22454643)
2012
11
Malignant transformation of a mature cystic ovarian teratoma into thyroid carcinoma, mucinous adenocarcinoma, and strumal carcinoid: a case report and literature review. (23029627)
2012
12
Metastatic mucinous adenocarcinoma of the orbit. (21281073)
2011
13
The clinical value of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography in postoperative patients with gastrointestinal mucinous adenocarcinoma. (21956489)
2011
14
Primary mucinous adenocarcinoma of the renal pelvis and ureter. (22808823)
2011
15
Retroperitoneal primary mucinous adenocarcinoma: A case report. (22848240)
2011
16
A role of 18F-fluorodeoxyglucose positron emission/computed tomography in a strategy for abdominal wall metastasis of colorectal mucinous adenocarcinoma developed after laparoscopic surgery. (21352607)
2011
17
Expression of mucin antigens (MUC1 and MUC16) as a prognostic factor for mucinous adenocarcinoma of the uterine cervix. (20598042)
2010
18
Mucinous adenocarcinoma showing different clinicopathological and molecular characteristics in relation to different colorectal cancer subgroups. (20532535)
2010
19
Gene expression profiling of colorectal mucinous adenocarcinomas. (20485009)
2010
20
Perianal mucinous adenocarcinoma arising from chronic anorectal fistulae: a review from single institution. (19205706)
2009
21
Clinicopathologic features and survival of patients with colorectal mucinous, signet-ring cell or non-mucinous adenocarcinoma: experience at an institution in southern China. (19719934)
2009
22
Mucinous adenocarcinoma of the prostate: MRI and MR spectroscopy features. (19696265)
2009
23
Successful sphincter-sparing local excision for mucinous adenocarcinoma associated with chronic fistula in ano using preoperative MRI evaluation. (19731857)
2008
24
Mucinous adenocarcinoma of the thymus: a case report. (18670316)
2008
25
Primary mucinous adenocarcinoma of renal pelvis with carcinoembryonic antigen production. (18291507)
2008
26
Two subtypes of mucinous adenocarcinoma of the colorectum: clinicopathological and genetic features. (18301950)
2008
27
Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report. (18094900)
2007
28
Mucinous adenocarcinoma of the rectum with breast and ocular metastases. (16644510)
2006
29
Mucinous adenocarcinoma of posterior urethra. Report of a case. (15901135)
2005
30
Incidence and survival of mucinous adenocarcinoma of the colorectum: a population-based study from an Asian country. (14719155)
2004
31
Mucinous adenocarcinoma arising from fistula-in-ano: findings on MRI. (12942309)
2003
32
Case of mucinous adenocarcinoma with porcelain gallbladder. (12859733)
2003
33
Mucinous adenocarcinoma of ectopic breast tissue of the vulva. (12296762)
2002
34
Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma. (12107080)
2002
35
Mucinous adenocarcinoma of the ovary metastatic to the eye: report of a case with diagnosis by fine needle aspiration biopsy. (11575663)
2001
36
Mucinous adenocarcinoma of renal pelvis and villous adenoma of bladder after a caecal augmentation of bladder. (10075375)
1999
37
Giant mucinous ovarian tumor with low malignant potential with foci of well-differentiated mucinous adenocarcinoma masked by massive obesity. A case report. (7884758)
1994
38
Neoplastic Paneth cells in a mucinous adenocarcinoma of the bladder. (8298887)
1994
39
Cystic mucinous adenocarcinoma of the lung. Two cases of cystic variant of mucus-producing lung adenocarcinoma. (1311665)
1992
40
Primary mucinous adenocarcinoma of the lung with signet-ring cells: a histochemical comparison with signet-ring cell carcinomas of other sites. (2478443)
1989
41
Elderly man with hematuria and a pelvic mass. Mucinous adenocarcinoma of the urachus. (3036743)
1987
42
Primary mucinous adenocarcinoma of the trachea: the case for complete surgical resection. (2982060)
1985
43
Mucinous adenocarcinoma of the eyelid. A case report. (6329149)
1984
44
Mucinous adenocarcinoma in anorectal fistulae. (6327491)
1984
45
Pseudomyxoma peritonei associated with mucinous adenocarcinoma of the pancreas: CT findings and CT-guided biopsy. (6323557)
1984
46
Acute disseminated intravascular coagulation as the presenting and predominant clinical manifestation in a patient with a mucinous adenocarcinoma. (4376755)
1974
47
Calcifying mucinous adenocarcinoma of the stomach. (4290508)
1967
48
Mucinous adenocarcinoma of the urinary tract. (4290108)
1966
49
Mucinous adenocarcinoma of the urachus; report of a case. (13180890)
1954
50
Mucinous adenocarcinoma of the pelvis of the kidney. (18899418)
1948

Variations for Mucinous Adenocarcinoma

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Expression for genes affiliated with Mucinous Adenocarcinoma

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Search GEO for disease gene expression data for Mucinous Adenocarcinoma.

Pathways for genes affiliated with Mucinous Adenocarcinoma

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Compounds for genes affiliated with Mucinous Adenocarcinoma

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Compounds related to Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 57)
idCompoundScoreTop Affiliating Genes
1deoxycholic acid43 28 24 1212.8CDX2, MUC2
2deoxyribonucleic acid439.7AMACR, CDKN2A
3temozolomide43 1210.5CDKN2A, VIM
4eosin439.4MUC1, VIM
5s 100439.4MUC1, VIM
6reticulin439.4VIM, MUC1
7mucicarmine439.4MUC1, VIM
8roscovitine439.4VIM, CDKN2A
9fatty acid439.3CDKN2A, CDX2, AMACR
10b 723439.3MUC1, VIM
11guanosine43 24 1211.2CDKN2A, VIM
12crcs439.2CDKN2A, MUC1, MUC2
13galactose439.2MUC1, MUC2
14agarose439.2CDKN2A, MUC1, MUC2
15neomycin439.2VIM, CDKN2A
165fluorouracil439.2CDKN2A, MUC1, MUC2
17vitamin d439.1AMACR, VIM, CDX2
18progestin439.0MUC1, VIM
19purine43 2410.0MUC1, CDKN2A
20azathioprine43 2 49 1212.0CDKN2A, MUC2, VIM
21cytarabine43 49 1210.9CDKN2A, MUC1, VIM
22adriamycin438.9VIM, MUC1, CDKN2A
23folate438.9VIM, MUC1, CDKN2A
24dmso438.9MUC1, MUC2, VIM
25agar438.9VIM, MUC1, CDKN2A
26chloramphenicol43 2 49 1211.9CDKN2A, MUC1, VIM
2712-o-tetradecanoylphorbol 13-acetate438.8VIM, MUC2, MUC1
28cholesterol43 28 24 1211.8AMACR, MUC2, MUC1, CDKN2A
29forskolin43 49 1210.8VIM, MUC2, MUC1
30glucose438.7CDKN2A, MUC1, MUC2, AMACR
31creatinine438.7CDKN2A, MUC1, VIM
32cyclic amp43 249.7VIM, MUC1, CDKN2A
335-aza-2deoxycytidine438.6CDKN2A, CDX2, MUC2, VIM
34biotin43 24 1210.5AMACR, VIM, MUC1, CDKN2A
35vegf438.5CDKN2A, MUC1, VIM
36testosterone43 59 24 1211.5CDKN2A, MUC1, VIM, AMACR
37methotrexate49 43 1210.4VIM, MUC2, MUC1, CDKN2A
38actinomycin d438.4VIM, MUC2, MUC1, CDKN2A
39lipid438.4AMACR, VIM, MUC1, CDKN2A
40calcium43 49 24 1211.3AMACR, MUC2, MUC1, CDX2, CDKN2A
41oligonucleotide438.2AMACR, VIM, MUC2, CDX2, CDKN2A
42serine438.2CDKN2A, MUC1, MUC2, VIM
43hematoxylin438.0CDKN2A, MUC1, MUC2, VIM, AMACR
44dexamethasone43 49 28 1211.0CDKN2A, MUC1, MUC2, VIM, AMACR
45retinoic acid43 249.0AMACR, VIM, MUC2, MUC1, CDKN2A
46butyrate438.0VIM, MUC2, MUC1, CDX2, CDKN2A
47paraffin437.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
48progesterone43 28 59 24 1211.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
49estrogen437.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
50cysteine437.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A

GO Terms for genes affiliated with Mucinous Adenocarcinoma

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Cellular components related to Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1peroxisomeGO:00057779.2VIM, AMACR
2Golgi lumenGO:00057969.0MUC1, MUC2

Biological processes related to Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:00162669.3MUC1, MUC2

Molecular functions related to Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1p53 bindingGO:00020399.3CDKN2A, MUC1

Products for genes affiliated with Mucinous Adenocarcinoma

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Sources for Mucinous Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet