MCID: MCN001
MIFTS: 54

Mucinous Adenocarcinoma malady

Cancer diseases category
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Summaries for Mucinous Adenocarcinoma

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8Disease Ontology, 65Wikipedia, 33MalaCards
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Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, which produce mucin.

MalaCards: Mucinous Adenocarcinoma, also known as mucin-producing adenocarcinoma, is related to adenocarcinoma and pseudomyxoma peritonei. An important gene associated with Mucinous Adenocarcinoma is AMACR (alpha-methylacyl-CoA racemase), and among its related pathways are O-linked glycosylation of mucins and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. The compounds deoxycholic acid and deoxyribonucleic acid have been mentioned in the context of this disorder. Affiliated tissues include prostate, colon and skin, and related mouse phenotypes are tumorigenesis and digestive/alimentary.

Wikipedia:65 Mucinous carcinoma is a type of cancer that arises from epithelial cells; these line certain internal... more...

Aliases & Classifications for Mucinous Adenocarcinoma

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8Disease Ontology, 10DISEASES, 62UMLS, 40NCIt, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

mucinous adenocarcinoma 8 10
mucin-producing adenocarcinoma 8 62
pseudomyxoma peritonei with unknown primary site 8
mucin-secreting adenocarcinoma 8
mucin-secreting carcinoma 8
adenocarcinoma, mucinous 62
mucous carcinoma 8


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Disease Ontology8 DOID:3030
NCIt40 C26712
SNOMED-CT58 72495009, 900006
MeSH35 D002288

Related Diseases for Mucinous Adenocarcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Mucinous Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 162)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma31.8VIM, MUC2, MUC1, CDX2, CDKN2A, AMACR
2pseudomyxoma peritonei31.1MUC2, CDX2
3adenocarcinoma in situ30.6CDKN2A
4adenoma30.5AMACR, CDKN2A, CDX2, MUC2, MUC1
5neuroendocrine carcinoma30.5MUC1, CDX2
6cystadenocarcinoma30.3MUC1, MUC2
7ovarian cancer30.2AMACR, CDKN2A, MUC1
8nephrogenic adenoma30.2AMACR
9colorectal cancer30.2MUC2, CDKN2A, CDX2, AMACR
10gallbladder cancer30.1CDX2, MUC2
11colon cancer30.0AMACR, MUC2, CDX2
12adenoid cystic carcinoma30.0VIM, MUC1
13endometrial carcinoma30.0MUC1, CDX2, CDKN2A
14lung adenocarcinoma30.0MUC1, CDX2, CDKN2A, AMACR
15prostatitis10.8
16mucinous adenocarcinoma of the appendix10.7
17ovarian mucinous adenocarcinoma10.5
18teratoma10.5
19colon mucinous adenocarcinoma10.5
20endometrial mucinous adenocarcinoma10.5
21endocervicitis10.4
22cystic teratoma10.4
23peritonitis10.4
24crohn's disease10.4
25anal fistula10.3
26mucinous adenocarcinoma of ovary10.3
27villous adenoma10.3
28large cell neuroendocrine carcinoma10.3
29intestinal variant cervical mucinous adenocarcinoma10.3
30villoglandular variant cervical mucinous adenocarcinoma10.3
31endocervical type cervical mucinous adenocarcinoma10.3
32signet ring cell variant cervical mucinous adenocarcinoma10.3
33intussusception10.3
34fallopian tube mucinous adenocarcinoma10.3
35uterine ligament mucinous adenocarcinoma10.3
36bile duct mucinous adenocarcinoma10.3
37ampulla of vater mucinous adenocarcinoma10.3
38rectum mucinous adenocarcinoma10.3
39appendix adenocarcinoma10.3
40cervical mucinous adenocarcinoma10.3
41thyroiditis10.3
42urachal cyst10.3
43ulcerative colitis10.2
44clear cell adenocarcinoma10.2
45anal colloid adenocarcinoma10.2
46cervicitis10.2
47pyelonephritis10.2
48biliary papillomatosis10.1MUC2
49eccrine porocarcinoma10.1MUC1
50hidradenoma10.1MUC1

Graphical network of the top 20 diseases related to Mucinous Adenocarcinoma:



Diseases related to mucinous adenocarcinoma

Symptoms for Mucinous Adenocarcinoma

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Drugs & Therapeutics for Mucinous Adenocarcinoma

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Mucinous Adenocarcinoma

Search NIH Clinical Center for Mucinous Adenocarcinoma

Genetic Tests for Mucinous Adenocarcinoma

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Anatomical Context for Mucinous Adenocarcinoma

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33MalaCards
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MalaCards organs/tissues related to Mucinous Adenocarcinoma:

33
Prostate, Colon, Skin, Ovary, Appendix, Lung, Pancreas, Cervix, Salivary gland, Kidney, Breast, Thyroid, Thymus, Testis, Liver, Eye, Lymph node, Heart, Uterus, Small intestine, Trachea, T cells, Placenta, Brain, Tongue

Animal Models for Mucinous Adenocarcinoma or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Mucinous Adenocarcinoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.4MUC2, MUC1, CDX2, CDKN2A
2MP:00053818.4CDKN2A, CDX2, MUC1, MUC2
3MP:00053798.1MUC2, MUC1, CDX2, CDKN2A
4MP:00107687.7CDKN2A, CDX2, MUC2, VIM, AMACR
5MP:00053787.6AMACR, VIM, MUC2, CDX2, CDKN2A
6MP:00053767.2CDKN2A, CDX2, MUC1, MUC2, VIM, AMACR

Publications for Mucinous Adenocarcinoma

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52PubMed
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Articles related to Mucinous Adenocarcinoma:

(show top 50)    (show all 434)
idTitleAuthorsYear
1
The "drunken honeycomb" feature of pulmonary mucinous adenocarcinoma: a diagnostic pitfall of bronchial brushing cytology. (21563323)
2013
2
HNF4I+ as a marker for invasive mucinous adenocarcinoma of the lung. (23108025)
2013
3
Metastatic appendiceal goblet cell carcinoid masquerading as mucinous adenocarcinoma in effusion cytology: A diagnostic pitfall. (23833405)
2013
4
Bilateral breast metastasis from mucinous adenocarcinoma of the rectum: a case report and review of the literature. (24022315)
2013
5
Endobronchial ultrasound-guided transbronchial needle aspiration diagnosis of mediastinal lymph node metastasis of mucinous adenocarcinoma: arborizing stromal meshwork fragments as a diagnostic clue. (22298306)
2013
6
Mucinous adenocarcinoma arising from diffuse serrated adenoma of the appendix which mimics appendicular abscess. (23012662)
2012
7
Unusual isolated perineal recurrence in mucinous adenocarcinoma of the rectum after abdominoperineal resection: usefulness of dual-time-point FDG PET in evaluating mucinous tumors. (22955074)
2012
8
Mucinous adenocarcinoma of the intestinal type arising from mature cystic teratoma of the ovary: a rare case report and review of the literature. (23216975)
2012
9
A rare case of mucinous adenocarcinoma of the colon presenting as ileoileal intussusception in an adult. (22454643)
2012
10
Malignant transformation of a mature cystic ovarian teratoma into thyroid carcinoma, mucinous adenocarcinoma, and strumal carcinoid: a case report and literature review. (23029627)
2012
11
Metastatic mucinous adenocarcinoma of the orbit. (21281073)
2011
12
The clinical value of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography in postoperative patients with gastrointestinal mucinous adenocarcinoma. (21956489)
2011
13
Primary mucinous adenocarcinoma of the renal pelvis and ureter. (22808823)
2011
14
Retroperitoneal primary mucinous adenocarcinoma: A case report. (22848240)
2011
15
A role of 18F-fluorodeoxyglucose positron emission/computed tomography in a strategy for abdominal wall metastasis of colorectal mucinous adenocarcinoma developed after laparoscopic surgery. (21352607)
2011
16
Expression of mucin antigens (MUC1 and MUC16) as a prognostic factor for mucinous adenocarcinoma of the uterine cervix. (20598042)
2010
17
Mucinous adenocarcinoma showing different clinicopathological and molecular characteristics in relation to different colorectal cancer subgroups. (20532535)
2010
18
Gene expression profiling of colorectal mucinous adenocarcinomas. (20485009)
2010
19
Perianal mucinous adenocarcinoma arising from chronic anorectal fistulae: a review from single institution. (19205706)
2009
20
Clinicopathologic features and survival of patients with colorectal mucinous, signet-ring cell or non-mucinous adenocarcinoma: experience at an institution in southern China. (19719934)
2009
21
Mucinous adenocarcinoma of the prostate: MRI and MR spectroscopy features. (19696265)
2009
22
Primary mucinous adenocarcinoma of renal pelvis with carcinoembryonic antigen production. (18291507)
2008
23
Two subtypes of mucinous adenocarcinoma of the colorectum: clinicopathological and genetic features. (18301950)
2008
24
Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report. (18094900)
2007
25
Mucinous adenocarcinoma of the rectum with breast and ocular metastases. (16644510)
2006
26
Intraductal papillary mucinous adenocarcinoma of the bile ducts. (16923498)
2006
27
Mucinous adenocarcinoma of posterior urethra. Report of a case. (15901135)
2005
28
Incidence and survival of mucinous adenocarcinoma of the colorectum: a population-based study from an Asian country. (14719155)
2004
29
Mucinous adenocarcinoma arising from fistula-in-ano: findings on MRI. (12942309)
2003
30
Case of mucinous adenocarcinoma with porcelain gallbladder. (12859733)
2003
31
Mucinous adenocarcinoma of ectopic breast tissue of the vulva. (12296762)
2002
32
Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma. (12107080)
2002
33
Mucinous adenocarcinoma of the ovary metastatic to the eye: report of a case with diagnosis by fine needle aspiration biopsy. (11575663)
2001
34
Mucinous adenocarcinoma of renal pelvis and villous adenoma of bladder after a caecal augmentation of bladder. (10075375)
1999
35
Giant mucinous ovarian tumor with low malignant potential with foci of well-differentiated mucinous adenocarcinoma masked by massive obesity. A case report. (7884758)
1994
36
Neoplastic Paneth cells in a mucinous adenocarcinoma of the bladder. (8298887)
1994
37
Signet-ring mucinous adenocarcinoma of the pancreas. (7865839)
1994
38
Cystic mucinous adenocarcinoma of the lung. Two cases of cystic variant of mucus-producing lung adenocarcinoma. (1311665)
1992
39
Primary mucinous adenocarcinoma of the lung with signet-ring cells: a histochemical comparison with signet-ring cell carcinomas of other sites. (2478443)
1989
40
Elderly man with hematuria and a pelvic mass. Mucinous adenocarcinoma of the urachus. (3036743)
1987
41
Primary mucinous adenocarcinoma of the trachea: the case for complete surgical resection. (2982060)
1985
42
Mucinous adenocarcinoma of the eyelid. A case report. (6329149)
1984
43
Mucinous adenocarcinoma in anorectal fistulae. (6327491)
1984
44
Pseudomyxoma peritonei associated with mucinous adenocarcinoma of the pancreas: CT findings and CT-guided biopsy. (6323557)
1984
45
Mucinous adenocarcinoma and clear cell adenocarcinoma arising in separate ovaries. (6293404)
1983
46
Acute disseminated intravascular coagulation as the presenting and predominant clinical manifestation in a patient with a mucinous adenocarcinoma. (4376755)
1974
47
Calcifying mucinous adenocarcinoma of the stomach. (4290508)
1967
48
Mucinous adenocarcinoma of the urinary tract. (4290108)
1966
49
Mucinous adenocarcinoma of the urachus; report of a case. (13180890)
1954
50
Mucinous adenocarcinoma of the pelvis of the kidney. (18899418)
1948

Variations for Mucinous Adenocarcinoma

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Expression for genes affiliated with Mucinous Adenocarcinoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mucinous Adenocarcinoma

Search GEO for disease gene expression data for Mucinous Adenocarcinoma.

Pathways for genes affiliated with Mucinous Adenocarcinoma

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50PathCards, 55Reactome, 30KEGG, 38NCBI BioSystems Database
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Compounds for genes affiliated with Mucinous Adenocarcinoma

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Sources:
45Novoseek, 29IUPHAR, 24HMDB, 11DrugBank, 3BitterDB, 51PharmGKB, 61Tocris Bioscience
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Compounds related to Mucinous Adenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idCompoundScoreTop Affiliating Genes
1deoxycholic acid45 29 24 1112.8CDX2, MUC2
2deoxyribonucleic acid459.7AMACR, CDKN2A
3temozolomide45 1110.5CDKN2A, VIM
4eosin459.4MUC1, VIM
5s 100459.4MUC1, VIM
6reticulin459.4VIM, MUC1
7mucicarmine459.4MUC1, VIM
8roscovitine459.4VIM, CDKN2A
9fatty acid459.3CDKN2A, CDX2, AMACR
10b 723459.3MUC1, VIM
11guanosine45 24 1111.2CDKN2A, VIM
12crcs459.2CDKN2A, MUC1, MUC2
13galactose459.2MUC1, MUC2
14agarose459.2CDKN2A, MUC1, MUC2
15neomycin459.2VIM, CDKN2A
165fluorouracil459.2CDKN2A, MUC1, MUC2
17vitamin d459.1AMACR, VIM, CDX2
18progestin459.0MUC1, VIM
19purine45 2410.0MUC1, CDKN2A
20azathioprine45 3 51 1112.0CDKN2A, MUC2, VIM
21cytarabine45 51 1110.9CDKN2A, MUC1, VIM
22adriamycin458.9VIM, MUC1, CDKN2A
23folate458.9VIM, MUC1, CDKN2A
24dmso458.9MUC1, MUC2, VIM
25agar458.9VIM, MUC1, CDKN2A
26chloramphenicol45 3 51 1111.9CDKN2A, MUC1, VIM
2712-o-tetradecanoylphorbol 13-acetate458.8VIM, MUC2, MUC1
28cholesterol45 29 24 1111.8AMACR, MUC2, MUC1, CDKN2A
29forskolin45 51 1110.8VIM, MUC2, MUC1
30glucose458.7CDKN2A, MUC1, MUC2, AMACR
31creatinine458.7CDKN2A, MUC1, VIM
32cyclic amp45 249.7VIM, MUC1, CDKN2A
335-aza-2deoxycytidine458.6CDKN2A, CDX2, MUC2, VIM
34biotin45 24 1110.5AMACR, VIM, MUC1, CDKN2A
35vegf458.5CDKN2A, MUC1, VIM
36testosterone45 61 24 1111.5CDKN2A, MUC1, VIM, AMACR
37methotrexate51 45 1110.4VIM, MUC2, MUC1, CDKN2A
38actinomycin d458.4VIM, MUC2, MUC1, CDKN2A
39lipid458.4AMACR, VIM, MUC1, CDKN2A
40calcium45 51 24 1111.3AMACR, MUC2, MUC1, CDX2, CDKN2A
41oligonucleotide458.2AMACR, VIM, MUC2, CDX2, CDKN2A
42serine458.2CDKN2A, MUC1, MUC2, VIM
43hematoxylin458.0CDKN2A, MUC1, MUC2, VIM, AMACR
44dexamethasone45 51 29 1111.0CDKN2A, MUC1, MUC2, VIM, AMACR
45retinoic acid45 249.0AMACR, VIM, MUC2, MUC1, CDKN2A
46butyrate458.0VIM, MUC2, MUC1, CDX2, CDKN2A
47paraffin457.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
48progesterone45 29 61 24 1111.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
49estrogen457.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
50cysteine457.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A

GO Terms for genes affiliated with Mucinous Adenocarcinoma

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16Gene Ontology
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Cellular components related to Mucinous Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peroxisomeGO:0057779.2VIM, AMACR
2Golgi lumenGO:0057969.0MUC1, MUC2

Biological processes related to Mucinous Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:0162669.3MUC1, MUC2

Molecular functions related to Mucinous Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1p53 bindingGO:0020399.3CDKN2A, MUC1

Products for genes affiliated with Mucinous Adenocarcinoma

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Sources for Mucinous Adenocarcinoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet