MCID: MCN001
MIFTS: 55

Mucinous Adenocarcinoma malady

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Summaries for Mucinous Adenocarcinoma

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Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, which produce mucin.

MalaCards based summary: Mucinous Adenocarcinoma, also known as pseudomyxoma peritonei with unknown primary site, is related to pseudomyxoma peritonei and adenocarcinoma in situ. An important gene associated with Mucinous Adenocarcinoma is AMACR (alpha-methylacyl-CoA racemase), and among its related pathways are O-linked glycosylation of mucins and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. The compounds deoxycholic acid and deoxyribonucleic acid have been mentioned in the context of this disorder. Affiliated tissues include prostate, colon and skin, and related mouse phenotypes are tumorigenesis and digestive/alimentary.

Wikipedia:65 Mucinous carcinoma is a type of cancer that arises from epithelial cells; these line certain internal... more...

Aliases & Classifications for Mucinous Adenocarcinoma

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Mucinous Adenocarcinoma, Aliases & Descriptions:

Name: Mucinous Adenocarcinoma 8 10
Pseudomyxoma Peritonei with Unknown Primary Site 8 62
Mucin-Producing Adenocarcinoma 8 62
Mucin-Secreting Adenocarcinoma 8
 
Mucin-Secreting Carcinoma 8
Adenocarcinoma, Mucinous 62
Mucous Carcinoma 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


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Disease Ontology8 DOID:3030
NCIt39 C26712
SNOMED-CT57 72495009, 900006
MeSH34 D002288

Related Diseases for Mucinous Adenocarcinoma

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Diseases related to Mucinous Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 169)
idRelated DiseaseScoreTop Affiliating Genes
1pseudomyxoma peritonei31.4CDX2, MUC2
2adenocarcinoma in situ31.1CDKN2A
3adenocarcinoma30.9AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
4nephrogenic adenoma30.8AMACR
5cystadenocarcinoma30.7MUC1, MUC2
6neuroendocrine carcinoma30.6CDX2, MUC1
7gallbladder cancer30.4MUC2, CDX2
8mucoepidermoid carcinoma30.3MUC2, MUC1
9bladder carcinoma30.1CDKN2A, MUC2
10adenoma30.1AMACR, MUC2, MUC1, CDX2, CDKN2A
11ovarian cancer30.1AMACR, MUC1, CDKN2A
12colorectal cancer30.1AMACR, MUC2, CDX2, CDKN2A
13endometrial carcinoma30.0CDKN2A, CDX2, MUC1
14lung adenocarcinoma29.8CDKN2A, CDX2, MUC1, AMACR
15prostatitis10.8
16mucinous adenocarcinoma of the appendix10.7
17ovarian mucinous adenocarcinoma10.6
18teratoma10.5
19colon mucinous adenocarcinoma10.5
20endometrial mucinous adenocarcinoma10.5
21biliary papillomatosis10.4MUC2
22endocervicitis10.4
23colitis10.4
24cystic teratoma10.4
25peritonitis10.4
26mucinous adenocarcinoma of ovary10.4
27eccrine porocarcinoma10.4MUC1
28crohn's disease10.4
29hidradenoma10.4MUC1
30syringoma10.4MUC1
31anal fistula10.3
32villous adenoma10.3
33appendix adenocarcinoma10.3
34adenomatoid tumor10.3VIM
35paraganglioma10.3VIM
36ulcerative colitis10.3
37signet ring cell variant cervical mucinous adenocarcinoma10.3
38large cell neuroendocrine carcinoma10.3
39intestinal variant cervical mucinous adenocarcinoma10.3
40villoglandular variant cervical mucinous adenocarcinoma10.3
41endocervical type cervical mucinous adenocarcinoma10.3
42intussusception10.3
43anal colloid adenocarcinoma10.3
44fallopian tube mucinous adenocarcinoma10.3
45ampulla of vater mucinous adenocarcinoma10.3
46bile duct mucinous adenocarcinoma10.3
47uterine ligament mucinous adenocarcinoma10.3
48rectum mucinous adenocarcinoma10.3
49cervical mucinous adenocarcinoma10.3
50thyroiditis10.3

Graphical network of the top 20 diseases related to Mucinous Adenocarcinoma:



Diseases related to mucinous adenocarcinoma

Symptoms for Mucinous Adenocarcinoma

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Drugs & Therapeutics for Mucinous Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Mucinous Adenocarcinoma

Search NIH Clinical Center for Mucinous Adenocarcinoma

Genetic Tests for Mucinous Adenocarcinoma

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Anatomical Context for Mucinous Adenocarcinoma

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MalaCards organs/tissues related to Mucinous Adenocarcinoma:

32
Prostate, Colon, Skin, Appendix, Ovary, Lung, Pancreas, Cervix, Salivary gland, Kidney, Breast, Eye, Thymus, Liver, Thyroid, Lymph node, Testis, Brain, Heart, Small intestine, Uterus, Placenta, T cells, Tongue, Trachea

Animal Models for Mucinous Adenocarcinoma or affiliated genes

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MGI Mouse Phenotypes related to Mucinous Adenocarcinoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.4MUC2, MUC1, CDX2, CDKN2A
2MP:00053818.4CDKN2A, CDX2, MUC1, MUC2
3MP:00053798.1MUC2, MUC1, CDX2, CDKN2A
4MP:00107687.7CDKN2A, CDX2, MUC2, VIM, AMACR
5MP:00053787.6AMACR, VIM, MUC2, CDX2, CDKN2A
6MP:00053767.2CDKN2A, CDX2, MUC1, MUC2, VIM, AMACR

Publications for Mucinous Adenocarcinoma

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Articles related to Mucinous Adenocarcinoma:

(show top 50)    (show all 458)
idTitleAuthorsYear
1
The "drunken honeycomb" feature of pulmonary mucinous adenocarcinoma: a diagnostic pitfall of bronchial brushing cytology. (21563323)
2013
2
HNF4I+ as a marker for invasive mucinous adenocarcinoma of the lung. (23108025)
2013
3
Metastatic appendiceal goblet cell carcinoid masquerading as mucinous adenocarcinoma in effusion cytology: A diagnostic pitfall. (23833405)
2013
4
Bilateral breast metastasis from mucinous adenocarcinoma of the rectum: a case report and review of the literature. (24022315)
2013
5
Endobronchial ultrasound-guided transbronchial needle aspiration diagnosis of mediastinal lymph node metastasis of mucinous adenocarcinoma: arborizing stromal meshwork fragments as a diagnostic clue. (22298306)
2013
6
Mucinous adenocarcinoma arising from diffuse serrated adenoma of the appendix which mimics appendicular abscess. (23012662)
2012
7
Unusual isolated perineal recurrence in mucinous adenocarcinoma of the rectum after abdominoperineal resection: usefulness of dual-time-point FDG PET in evaluating mucinous tumors. (22955074)
2012
8
Mucinous adenocarcinoma of the intestinal type arising from mature cystic teratoma of the ovary: a rare case report and review of the literature. (23216975)
2012
9
A rare case of mucinous adenocarcinoma of the colon presenting as ileoileal intussusception in an adult. (22454643)
2012
10
Malignant transformation of a mature cystic ovarian teratoma into thyroid carcinoma, mucinous adenocarcinoma, and strumal carcinoid: a case report and literature review. (23029627)
2012
11
Metastatic mucinous adenocarcinoma of the orbit. (21281073)
2011
12
The clinical value of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography in postoperative patients with gastrointestinal mucinous adenocarcinoma. (21956489)
2011
13
Primary mucinous adenocarcinoma of the renal pelvis and ureter. (22808823)
2011
14
Retroperitoneal primary mucinous adenocarcinoma: A case report. (22848240)
2011
15
A role of 18F-fluorodeoxyglucose positron emission/computed tomography in a strategy for abdominal wall metastasis of colorectal mucinous adenocarcinoma developed after laparoscopic surgery. (21352607)
2011
16
Expression of mucin antigens (MUC1 and MUC16) as a prognostic factor for mucinous adenocarcinoma of the uterine cervix. (20598042)
2010
17
Mucinous adenocarcinoma showing different clinicopathological and molecular characteristics in relation to different colorectal cancer subgroups. (20532535)
2010
18
Gene expression profiling of colorectal mucinous adenocarcinomas. (20485009)
2010
19
Perianal mucinous adenocarcinoma arising from chronic anorectal fistulae: a review from single institution. (19205706)
2009
20
Clinicopathologic features and survival of patients with colorectal mucinous, signet-ring cell or non-mucinous adenocarcinoma: experience at an institution in southern China. (19719934)
2009
21
Mucinous adenocarcinoma of the prostate: MRI and MR spectroscopy features. (19696265)
2009
22
Successful sphincter-sparing local excision for mucinous adenocarcinoma associated with chronic fistula in ano using preoperative MRI evaluation. (19731857)
2008
23
Mucinous adenocarcinoma of the thymus: a case report. (18670316)
2008
24
Primary mucinous adenocarcinoma of renal pelvis with carcinoembryonic antigen production. (18291507)
2008
25
Two subtypes of mucinous adenocarcinoma of the colorectum: clinicopathological and genetic features. (18301950)
2008
26
Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report. (18094900)
2007
27
Mucinous adenocarcinoma of the rectum with breast and ocular metastases. (16644510)
2006
28
Mucinous adenocarcinoma of posterior urethra. Report of a case. (15901135)
2005
29
Incidence and survival of mucinous adenocarcinoma of the colorectum: a population-based study from an Asian country. (14719155)
2004
30
Mucinous adenocarcinoma arising from fistula-in-ano: findings on MRI. (12942309)
2003
31
Case of mucinous adenocarcinoma with porcelain gallbladder. (12859733)
2003
32
Mucinous adenocarcinoma of ectopic breast tissue of the vulva. (12296762)
2002
33
Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma. (12107080)
2002
34
Mucinous adenocarcinoma of the ovary metastatic to the eye: report of a case with diagnosis by fine needle aspiration biopsy. (11575663)
2001
35
Mucinous adenocarcinoma of renal pelvis and villous adenoma of bladder after a caecal augmentation of bladder. (10075375)
1999
36
Giant mucinous ovarian tumor with low malignant potential with foci of well-differentiated mucinous adenocarcinoma masked by massive obesity. A case report. (7884758)
1994
37
Neoplastic Paneth cells in a mucinous adenocarcinoma of the bladder. (8298887)
1994
38
Cystic mucinous adenocarcinoma of the lung. Two cases of cystic variant of mucus-producing lung adenocarcinoma. (1311665)
1992
39
Primary mucinous adenocarcinoma of the lung with signet-ring cells: a histochemical comparison with signet-ring cell carcinomas of other sites. (2478443)
1989
40
Elderly man with hematuria and a pelvic mass. Mucinous adenocarcinoma of the urachus. (3036743)
1987
41
Primary mucinous adenocarcinoma of the trachea: the case for complete surgical resection. (2982060)
1985
42
Mucinous adenocarcinoma of the eyelid. A case report. (6329149)
1984
43
Mucinous adenocarcinoma in anorectal fistulae. (6327491)
1984
44
Pseudomyxoma peritonei associated with mucinous adenocarcinoma of the pancreas: CT findings and CT-guided biopsy. (6323557)
1984
45
Mucinous adenocarcinoma and clear cell adenocarcinoma arising in separate ovaries. (6293404)
1983
46
Acute disseminated intravascular coagulation as the presenting and predominant clinical manifestation in a patient with a mucinous adenocarcinoma. (4376755)
1974
47
Calcifying mucinous adenocarcinoma of the stomach. (4290508)
1967
48
Mucinous adenocarcinoma of the urinary tract. (4290108)
1966
49
Mucinous adenocarcinoma of the urachus; report of a case. (13180890)
1954
50
Mucinous adenocarcinoma of the pelvis of the kidney. (18899418)
1948

Variations for Mucinous Adenocarcinoma

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Expression for genes affiliated with Mucinous Adenocarcinoma

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Expression patterns in normal tissues for genes affiliated with Mucinous Adenocarcinoma

Search GEO for disease gene expression data for Mucinous Adenocarcinoma.

Pathways for genes affiliated with Mucinous Adenocarcinoma

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Compounds for genes affiliated with Mucinous Adenocarcinoma

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Compounds related to Mucinous Adenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idCompoundScoreTop Affiliating Genes
1deoxycholic acid44 28 24 1112.8CDX2, MUC2
2deoxyribonucleic acid449.7AMACR, CDKN2A
3temozolomide44 1110.5CDKN2A, VIM
4eosin449.4MUC1, VIM
5s 100449.4MUC1, VIM
6reticulin449.4VIM, MUC1
7mucicarmine449.4MUC1, VIM
8roscovitine449.4VIM, CDKN2A
9fatty acid449.3CDKN2A, CDX2, AMACR
10b 723449.3MUC1, VIM
11guanosine44 24 1111.2CDKN2A, VIM
12crcs449.2CDKN2A, MUC1, MUC2
13galactose449.2MUC1, MUC2
14agarose449.2CDKN2A, MUC1, MUC2
15neomycin449.2VIM, CDKN2A
165fluorouracil449.2CDKN2A, MUC1, MUC2
17vitamin d449.1AMACR, VIM, CDX2
18progestin449.0MUC1, VIM
19purine44 2410.0MUC1, CDKN2A
20azathioprine44 2 50 1112.0CDKN2A, MUC2, VIM
21cytarabine44 50 1110.9CDKN2A, MUC1, VIM
22adriamycin448.9VIM, MUC1, CDKN2A
23folate448.9VIM, MUC1, CDKN2A
24dmso448.9MUC1, MUC2, VIM
25agar448.9VIM, MUC1, CDKN2A
26chloramphenicol44 2 50 1111.9CDKN2A, MUC1, VIM
2712-o-tetradecanoylphorbol 13-acetate448.8VIM, MUC2, MUC1
28cholesterol44 28 24 1111.8AMACR, MUC2, MUC1, CDKN2A
29forskolin44 50 1110.8VIM, MUC2, MUC1
30glucose448.7CDKN2A, MUC1, MUC2, AMACR
31creatinine448.7CDKN2A, MUC1, VIM
32cyclic amp44 249.7VIM, MUC1, CDKN2A
335-aza-2deoxycytidine448.6CDKN2A, CDX2, MUC2, VIM
34biotin44 24 1110.5AMACR, VIM, MUC1, CDKN2A
35vegf448.5CDKN2A, MUC1, VIM
36testosterone44 61 24 1111.5CDKN2A, MUC1, VIM, AMACR
37methotrexate50 44 1110.4VIM, MUC2, MUC1, CDKN2A
38actinomycin d448.4VIM, MUC2, MUC1, CDKN2A
39lipid448.4AMACR, VIM, MUC1, CDKN2A
40calcium44 50 24 1111.3AMACR, MUC2, MUC1, CDX2, CDKN2A
41oligonucleotide448.2AMACR, VIM, MUC2, CDX2, CDKN2A
42serine448.2CDKN2A, MUC1, MUC2, VIM
43hematoxylin448.0CDKN2A, MUC1, MUC2, VIM, AMACR
44dexamethasone44 50 28 1111.0CDKN2A, MUC1, MUC2, VIM, AMACR
45retinoic acid44 249.0AMACR, VIM, MUC2, MUC1, CDKN2A
46butyrate448.0VIM, MUC2, MUC1, CDX2, CDKN2A
47paraffin447.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
48progesterone44 28 61 24 1111.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
49estrogen447.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A
50cysteine447.6AMACR, VIM, MUC2, MUC1, CDX2, CDKN2A

GO Terms for genes affiliated with Mucinous Adenocarcinoma

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Cellular components related to Mucinous Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peroxisomeGO:0057779.2VIM, AMACR
2Golgi lumenGO:0057969.0MUC1, MUC2

Biological processes related to Mucinous Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:0162669.3MUC1, MUC2

Molecular functions related to Mucinous Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1p53 bindingGO:0020399.3CDKN2A, MUC1

Products for genes affiliated with Mucinous Adenocarcinoma

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Sources for Mucinous Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet