MCID: MCC002
MIFTS: 43

Mucocutaneous Leishmaniasis malady

Category: Infectious diseases

Aliases & Classifications for Mucocutaneous Leishmaniasis

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Aliases & Descriptions for Mucocutaneous Leishmaniasis:

Name: Mucocutaneous Leishmaniasis 10 12 65
American Cutaneous Leishmaniasis 10 65
Mucocutaneous Leishmaniasis, American 10
American Mucocutaneous Leishmaniasis 10
 
Cutaneous Leishmaniasis, American 10
New World Cutaneous Leishmaniasis 10
Mucocutaneous Leishmaniasis, 10
Leishmaniasis, Mucocutaneous 36

Classifications:



External Ids:

Disease Ontology10 DOID:9155
ICD1027 B55.2
ICD9CM29 085.5
MeSH36 D007897
UMLS65 C1328252, C3495436

Summaries for Mucocutaneous Leishmaniasis

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Disease Ontology:10 A leishmaniasis that involves a chronic inflammatory process involving the nasal, pharyngeal, and laryngeal mucosa, which can lead to extensive tissue destruction, caused by protozoan parasites belonging to the genus Leishmania. The infection is characterized by granulomatous lesion which can destroy upper respiratory tract mucosa.

MalaCards based summary: Mucocutaneous Leishmaniasis, also known as american cutaneous leishmaniasis, is related to extrapulmonary tuberculosis and lymphocytic choriomeningitis. An important gene associated with Mucocutaneous Leishmaniasis is CD4 (CD4 Molecule), and among its related pathways are Primary immunodeficiency and IL-10 Pathway. Affiliated tissues include thyroid, liver and brain, and related mouse phenotypes are integument and endocrine/exocrine gland.

Related Diseases for Mucocutaneous Leishmaniasis

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Diseases related to Mucocutaneous Leishmaniasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 314)
idRelated DiseaseScoreTop Affiliating Genes
1extrapulmonary tuberculosis30.6CD4, IL4
2lymphocytic choriomeningitis30.4CD8A, TNF
3congenital heart block30.1IL10, IL4, TNF
4leishmaniasis10.6
5pituitary apoplexy10.4CD4, CD8A
6hyperhomocysteinemia10.4CD4, CD8A
7malignant cornea melanoma10.4CD4, CD8A
8acute cystitis10.4CD4, CD8A
9cd3epsilon deficiency10.4CD4, CD8A
10mycotic corneal ulcer10.4CD4, CD8A
11monkeypox10.4CD4, CD8A
12neurotic disorder10.4CD4, IL10
13rem sleep behavior disorder10.4CD4, CD8A
14toxic maculopathy10.4CD4, CD8A
15coronin-1a deficiency10.4CD4, CD8A
16leukocyte disease10.4CD4, CD8A
17desquamative interstitial pneumonia10.4CD4, CD8A
18microsporidiosis10.4CD4, CD8A
19late congenital syphilis10.4CD4, CD8A
20lichen disease10.4CD4, CD8A
21pityriasis rosea10.4CD4, CD8A
22enophthalmos10.4CD4, CD8A
23inflammatory leiomyosarcoma10.4CD4, CD8A
24myositis ossificans10.4CD4, CD8A
25juvenile spinal muscular atrophy10.4CD4, CD8A
26hyperinsulinism10.4CD4, CD8A
27rhabdoid cancer10.4CD4, CD8A
28paralytic squint10.4CD4, CD8A
29pharyngoconjunctival fever10.4CD4, CD8A
30vein disease10.4CD4, CD8A
31arcus senilis10.4CD4, CD8A
32rheumatic myocarditis10.4CD4, IL4
33autoimmune disease of cardiovascular system10.4CD4, CD8A
34status asthmaticus10.4CD4, IL4
35cervical incompetence10.4CD4, CD8A
36cycloplegia10.4IL10, IL4
37eosinophilic gastroenteritis10.4CD4, IL4
38internal hordeolum10.4CD4, CD8A
39mobitz type ii atrioventricular block10.4CD4, IL4
40interleukin-7 receptor alpha deficiency10.4CD4, CD8A
41dioctophymiasis10.4IL10, IL4
42female breast central part cancer10.3CD4, CD8A
43penicillin allergy10.3IL10, IL4
44superficial urinary bladder cancer10.3IL10, IL4
45neurofibromatosis10.3CD4, IL4
46buruli ulcer10.3IL10, IL4
47nemaline myopathy10.3CD4, CD8A
48clivus chordoma10.3CD4, CD8A
49parathyroid gland disease10.3CD4, CD8A
50ethmoid sinus squamous cell carcinoma10.3CD4, TNF

Graphical network of the top 20 diseases related to Mucocutaneous Leishmaniasis:



Diseases related to mucocutaneous leishmaniasis

Symptoms for Mucocutaneous Leishmaniasis

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Drugs & Therapeutics for Mucocutaneous Leishmaniasis

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Drugs for Mucocutaneous Leishmaniasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Anti-Infective AgentsPhase 2, Phase 3, Phase 117220
2Antiprotozoal AgentsPhase 2, Phase 3, Phase 11730
3meglumine antimoniatePhase 2, Phase 325
4Antiparasitic AgentsPhase 2, Phase 3, Phase 11854
5
Miconazoleapproved, investigationalPhase 2, Phase 1302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
6
Amphotericin Bapproved, investigationalPhase 2, Phase 11171397-89-314956, 5280965
Synonyms:
12633-72-6
1397-89-3
30782-62-8
5-18-10-00525 (Beilstein Handbook Reference)
54482-28-9
8055-20-7
AB00513832
ABLC
AC1L1CN2
AC1L24V6
AC1L70KF
AC1L73U6
AC1NQXTD
AC1NTQ32
AC1NUQG4
AC1NY9JC
AC1O7GCZ
AC1O8FQV
AC1O8PFK
AI3-26528
AMPH-B
AMPH-b
Abelcet
Abelecet
AmBisome (TN)
Ambap1397-89-3
Ambisome
Amfotericina B
Amfotericina B [INN-Spanish]
Ampho-Moronal
Amphocin
Amphomoronal
Amphortericin B
Amphotec
Amphotec (TN)
Amphotericin
Amphotericin .BETA.
Amphotericin B
Amphotericin B (JP15/USP/INN)
Amphotericin B Cholesterol Dispersion
Amphotericin B Cholesteryl Sulfate Complex
Amphotericin B Colloidal Dispersion
Amphotericin B [USAN:INN:JAN]
Amphotericin B, Lipid-based
Amphotericin B, Streptomyces sp.
Amphotericin-B
Amphotericine B
Amphotericine B [INN-French]
Amphotericinum
Amphotericinum B
Amphotericinum B [INN-Latin]
Amphotherizin
Amphotherizin [German]
Amphotéricine B
Amphozone
BIDD:GT0351
BPBio1_000374
BRN 0078342
BSPBio_000340
C-AmB
C06573
C47H73NO17
CCRIS 5963
CHEBI:2682
CHEMBL1200646
CHEMBL267345
CID10533925
CID10629638
CID10677275
CID14956
 
CID1972
CID352546
CID354192
CID5280965
CID5386092
CID5458486
CID5771695
CID6604295
CID6708817
CID6713692
CID9919339
D00203
DB00681
DivK1c_007045
EINECS 215-742-2
Fungilin
Fungisome
Fungisone
Fungizone
Fungizone (TN)
HMS1569A22
HSDB 3008
HSDB 3008 IAB
Halizon
I06-0257
KBio1_001989
KBio2_000551
KBio2_003119
KBio2_005687
KBioGR_002298
KBioSS_000551
LMPK06000002
LNS-AmB
LS-187721
LS-93
Liposomal Amphotericin B
Liposomal amphotericin b
MLS002702966
MolPort-006-392-260
Mysteclin-F
NCGC00014913
NCGC00090808-01
NCGC00098014-01
NCGC00179595-01
NCI527017
NCI60_004288
NCIStruc1_001042
NCIStruc2_000920
NKTR-024
NS 718
NSC 527017
NSC-527017
NSC527017
Prestwick0_000410
Prestwick1_000410
Prestwick2_000410
Prestwick3_000410
Prestwick_721
SMP1_000302
SMR001566780
SPBio_000715
SPBio_002279
ST50999656
SinuNase
SpecPlus_000949
Spectrum2_000818
Spectrum4_001779
Spectrum_000111
UNII-7XU7A7DROE
amophotericin B
amphotericin B liposomal
amphotericin b
7
MiltefosineapprovedPhase 2, Phase 13358066-85-63600
Synonyms:
1-Hexadecylphosphorylcholine
2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide, inner salt
3,5-Dioxa-4-phosphaunacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide
4-04-00-01460 (Beilstein Handbook Reference)
58066-85-6
AC1L1GAH
BRN 3690495
Baxter Oncology brand of miltefosine
Baxter brand of miltefosine
C039128
C15H32.C7H17NO4P
CHEBI:125047
CHEMBL125
CID3599
Choline hydroxide, hexadecyl hydrogen phosphate, inner salt
Choline phosphate, hexadecyl ester, hydroxide, inner salt
Choline phosphate, hexadecyl ester, hydroxide, inner salt (6CI)
Choline, hexadecyl hydrogen phosphate, inner salt
D 18506
D-18506
D02494
D18506
Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt
Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, innner salt
H-1850
HDPC
HMS1922D16
HMS2089J15
HePC
Hexadecyl 2-(trimethyl-.lambda.~5~-azanyl)ethyl hydrogen phosphate
 
Hexadecylphosphocholine
Hexadecylphosphorylcholine
I14-7244
IN1227
Impavido
LS-65132
M-7200
Miltefosin
Miltefosin C
Miltefosina
Miltefosina [INN-Spanish]
Miltefosine
Miltefosine (INN)
Miltefosine [INN:BAN]
Miltefosinum
Miltefosinum [INN-Latin]
Miltex
Miltéfosine
MolPort-003-665-519
Monohexadecylphosphocholine
Monohexadecylphosphorylcholine
NCGC00095169-01
NCGC00095169-02
NCGC00095169-03
NSC605583
Prasfarma brand of miltefosine
SPECTRUM1505329
ST51055612
TF-002
UNII-53EY29W7EC
hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
n-Hexadecylphosphorylcholine
8
Pentoxifyllineapproved, investigationalPhase 2906493-05-64740
Synonyms:
1,2,3,6-Tetrahydro-3,7-dimethyl-1-(5-oxohexyl)-2,6-purindion
1-(5-Oxohexyl)-3,7-dimethylxanthine
1-(5-Oxohexyl)theobromine
2a3c
3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxo-hexyl)-3,7-dihydro-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl) xantine
3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)xanthine
3,7-Dimethyl-1-(5-oxohexyl)xantine
3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
5-26-14-00081 (Beilstein Handbook Reference)
6493-05-6
AB00052363
AC1L1IUN
AKOS000541484
Agapurin
Agapurin Retard
Azupentat
BAS 00897429
BB_SC-2111
BIDD:GT0174
BL 191
BL-191
BL191
BPBio1_000167
BRD-K57569181-001-05-1
BRN 0558929
BSPBio_000151
BSPBio_003439
C07424
C13H18N4O3
CAS-1677687
CCRIS 6832
CHEMBL628
CID4740
CPD000035998
D00501
D010431
DB00806
Dimethyloxohexylxanthine
DivK1c_000729
Durapental
EHT 0201
EHT-0201
EHT-201
EHT0201
EINECS 229-374-5
EU-0100936
HMS1568H13
HMS1922E16
HMS2051N06
HMS2090H13
HMS2093G21
HMS502E11
Hemovas
I06-1592
IDI1_000729
IN1161
Ikomio
KBio1_000729
KBio2_001924
KBio2_004492
KBio2_007060
KBio3_002942
KBioGR_000893
KBioSS_001924
LS-149385
 
Lopac-P-1784
Lopac0_000936
MLS000079026
MLS000758298
MLS001201764
MolPort-001-823-263
NCGC00015801-01
NCGC00015801-02
NCGC00015801-04
NCGC00015801-10
NCGC00067069-02
NCGC00067069-03
NCGC00067069-04
NCGC00067069-05
NCGC00178062-01
NCGC00178062-02
NINDS_000729
NSC 637086
NSC637086
Oxpentifylline
P 1784
PDSP1_001015
PDSP2_000999
PENTOXYPHYLINE
PNX
Pentoxifilina
Pentoxifilina [INN-Spanish]
Pentoxifyllin
Pentoxifylline
Pentoxifylline (JAN/USP/INN)
Pentoxifylline [USAN:INN:JAN]
Pentoxifyllinum
Pentoxifyllinum [INN-Latin]
Pentoxil
Pentoxil (TN)
Pentoxiphyllin
Pentoxiphylline
Pentoxiphyllium
Pentoxyfylline
Pentoxyphyllin
Pentoxyphylline
Prestwick0_000196
Prestwick1_000196
Prestwick2_000196
Prestwick3_000196
Prestwick_608
Px
Ralofect
Rentylin
SAM001247011
SMR000035998
SPBio_001221
SPBio_002072
SPECTRUM1503611
SR-01000075641-4
STK177321
Spectrum2_001181
Spectrum3_001820
Spectrum4_000227
Spectrum5_001161
Spectrum_001444
Torental
Trental
Trental (TN)
UNII-SD6QCT3TSU
Vasofirin
Vazofirin
ZINC01530776
cis-9-Octadecenoyl coenzyme A
pentoxifylline
9Liposomal amphotericin BPhase 2, Phase 1117
10Antimony Sodium GluconatePhase 2, Phase 115
11Antifungal AgentsPhase 2, Phase 13015
12AnthelminticsPhase 2, Phase 1379
13Coal TarPhase 2165
14Radiation-Protective AgentsPhase 2333
15Vasodilator AgentsPhase 22926
16Protective AgentsPhase 25651
17Platelet Aggregation InhibitorsPhase 21935
18Phosphodiesterase InhibitorsPhase 21062
19AntioxidantsPhase 22442
20VaccinesPhase 16085
21Immunologic FactorsPhase 118483

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Low Antimonial Dosage in American Mucosal LeishmaniasisRecruitingNCT01301937Phase 2, Phase 3
2Clinical Trial of Miltefosine to Treat Mucosal LeishmaniasisCompletedNCT01377974Phase 2
3Miltefosine to Treat Mucocutaneous LeishmaniasisCompletedNCT01050907Phase 2
4Miltefosine for Mucosal LeishmaniasisCompletedNCT00373776Phase 1, Phase 2
5Miltefosine (Long Course) for Bolivian Mucosal LeishmaniasisCompletedNCT00373568Phase 1, Phase 2
6Sodium Stibogluconate Treatment of LeishmaniasisCompletedNCT00662012Phase 2
7Miltefosine to Treat Cutaneous Leishmaniasis in BoliviaCompletedNCT00233545Phase 2
8The Association of Miltefosine and Pentoxifylline to Treat Mucosal Leishmaniasis: A Clinical Trial in BrazilRecruitingNCT02530697Phase 2
9Use of Sodium Stibogluconate as a Treatment for LeishmaniasisEnrolling by invitationNCT00657618Phase 1, Phase 2
10Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Mucosal LeishmaniasisCompletedNCT00111514Phase 1
11Diagnosis and Treatment of Leishmanial InfectionsRecruitingNCT00344188
12Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World LeishmaniasisAvailableNCT00508963
13Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous LeishmaniasisNot yet recruitingNCT02429518
14Spermiogram Assessment in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous LeishmaniasisNot yet recruitingNCT02431429

Search NIH Clinical Center for Mucocutaneous Leishmaniasis


Cochrane evidence based reviews: leishmaniasis, mucocutaneous

Genetic Tests for Mucocutaneous Leishmaniasis

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Anatomical Context for Mucocutaneous Leishmaniasis

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MalaCards organs/tissues related to Mucocutaneous Leishmaniasis:

33
Thyroid, Liver, Brain, Lymph node, Endothelial, Prostate, Breast

Animal Models for Mucocutaneous Leishmaniasis or affiliated genes

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MGI Mouse Phenotypes related to Mucocutaneous Leishmaniasis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.7CD4, CD8A, IL10, IL4, TNF
2MP:00053797.9CD4, CD8A, IL10, IL4, LTA, TNF
3MP:00053917.4IL10, IL4, LTA, NID1, SCYL1, TNF
4MP:00107686.9CD4, CD8A, IL10, IL4, LTA, SCYL1
5MP:00053976.9CD4, CD8A, IL10, IL4, LTA, SCYL1
6MP:00053876.6CD4, CD8A, IL10, IL4, LTA, SCYL1
7MP:00036316.6CD4, CD8A, IL10, IL4, LTA, NID1

Publications for Mucocutaneous Leishmaniasis

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Articles related to Mucocutaneous Leishmaniasis:

(show top 50)    (show all 141)
idTitleAuthorsYear
1
The Burden of Undiagnosed Opioid Abuse Among Commercially Insured Individuals. (25929289)
2015
2
Endoscopic CO2 Laser Excision of a Ruptured Laryngocele: A novel "blue-dye" technique to assist dissection and avoid recurrent laryngeal nerve injury. (26584527)
2015
3
Reverse Correlation between MicroRNA-145 and FSCN1 Affecting Gastric Cancer Migration and Invasion. (26010149)
2015
4
An isolated left ventricular septal aneurysm in BehAset's disease. (25762556)
2015
5
Genotype CC of rs1800947 in the C-reactive protein gene may increase susceptibility to colorectal cancer: a meta-analysis. (24761881)
2014
6
Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5. (24594601)
2014
7
Mental nerve paresthesia secondary to initiation of endodontic therapy: a case report. (25110646)
2014
8
Characterization of genetic lesions in rhabdomyosarcoma using a high-density single nucleotide polymorphism array. (23578105)
2013
9
Headache associated with cough: a review. (23687906)
2013
10
Overexpression of EFEMP1 correlates with tumor progression and poor prognosis in human ovarian carcinoma. (24236050)
2013
11
Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent antitumor, antiangiogenic, and antimetastatic efficacy. (24097868)
2013
12
Cardiovascular importance of hyperglycemia and hypoglycemia. (23882057)
2013
13
The Role of Celiac Disease in Severity of Liver Disorders and Effect of a Gluten Free Diet on Diseases Improvement. (24348636)
2013
14
Brimonidine (Alphagan) associated anterior uveitis. (22257785)
2012
15
Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate and azathioprine. (22284862)
2012
16
Liver fibrosis may reduce the efficacy of budesonide in the treatment of autoimmune hepatitis and overlap syndrome. (22001521)
2012
17
Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice. (21325051)
2011
18
Autoimmune hepatitis, HLA and extended haplotypes. (20933106)
2011
19
A pilot study of gene/gene and gene/environment interactions in Alzheimer disease. (20682755)
2011
20
Sublingual lymph node metastasis of early tongue cancer: report of two cases and review of the literature. (21277742)
2011
21
Abelmoschus moschatus (Malvaceae), an aromatic plant, suitable for medical or food uses to improve insulin sensitivity. (19610024)
2010
22
Spontaneous thrombosis of congenital extrahepatic portosystemic shunt (Abernethy malformation) simulating inguinal hernia incarceration. (20551093)
2010
23
The volume perspective: a comparison of two excisional treatments for cervical intraepithelial neoplasia (laser versus LLETZ). (20156211)
2010
24
Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK. (19306925)
2009
25
Dual left ventricular restorations in a patient with cardiac sarcoidosis. (19380011)
2009
26
Pitavastatin suppresses formation and progression of cerebral aneurysms through inhibition of the nuclear factor kappaB pathway. (19190463)
2009
27
Angiotensin-(1-7) inhibits tumor angiogenesis in human lung cancer xenografts with a reduction in vascular endothelial growth factor. (19509262)
2009
28
Dynamic changes in transcription factor HIF-1alpha, rapid response protein, and membrane structure resistance following acute hypoxia]. (17396559)
2007
29
Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production. (16938404)
2006
30
Melanocytic lesions associated with dermatofibromas: a spectrum of lesions ranging from junctional nevus to malignant melanoma in situ. (15803191)
2005
31
Relation between chemotherapy dose, oestrogen receptor expression, and body-mass index. (16182899)
2005
32
The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4. (16144413)
2005
33
Jak2 tyrosine kinase residues glutamic acid 1024 and arginine 1113 form a hydrogen bond interaction that is essential for Jak-STAT signal transduction. (15543946)
2004
34
PET in the follow-up of differentiated thyroid cancer. (14512328)
2003
35
Quantitative evaluation of atopic blepharitis by scoring of eyelid conditions and measuring the water content of the skin and evaporation from the eyelid surface. (11322412)
2001
36
High sensitivity of human epidermal keratinocytes (HaCaT) to topoisomerase inhibitors. (11529882)
2001
37
Inhibition of human NK cell function by valinomycin, a toxin from Streptomyces griseus in indoor air. (10603383)
2000
38
Humoral immunity against the proline-rich peptide epitope of the IgA1 hinge region in IgA nephropathy. (10607764)
2000
39
Pick's disease is associated with mutations in the tau gene. (11117542)
2000
40
Carboxy-substituted cinnamides: a novel series of potent, orally active LTB4 receptor antagonists. (9888841)
1999
41
Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-XL and Bcl-2. (8781412)
1996
42
Evaluation of school children at high risk for fragile X syndrome utilizing buccal cell FMR-1 testing. (7943023)
1994
43
Acinar cell carcinoma of the pancreas. A histologic, immunocytochemical and ultrastructural study. (8003821)
1994
44
Treatment of liver metastases of human colon cancers in nude mice with somatostatin analogue RC-160. (1358828)
1992
45
Immunohistochemical and immunocytochemical localization of cathepsin E compared with cathepsin D. (1812728)
1991
46
The effect of luliberin and sulpiride on the secretion of gonadotropic hormones and prolactin in patients with obesity]. (2204052)
1990
47
Carrageenan-induced pulmonary emphysema of rabbit. (2711383)
1989
48
Neonatal familial hyperalphalipoproteinemia. (191726)
1977
49
Pseudomyxoma peritonei: an unusual case. (5082549)
1972
50
Case of Placenta Praevia. (20793788)
1845

Variations for Mucocutaneous Leishmaniasis

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Expression for genes affiliated with Mucocutaneous Leishmaniasis

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Search GEO for disease gene expression data for Mucocutaneous Leishmaniasis.

Pathways for genes affiliated with Mucocutaneous Leishmaniasis

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Pathways related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

(show all 22)
idSuper pathwaysScoreTop Affiliating Genes
19.7CD4, CD8A
29.6IL10, TNF
39.6IL10, TNF
4
Show member pathways
9.6IL10, TNF
59.3CD4, IL10, IL4
6
Show member pathways
9.3CD4, CD8A, IL4
7
Show member pathways
9.2CD4, IL10, TNF
8
Show member pathways
9.1IL10, IL4, TNF
98.8CD4, CD8A, IL10, TNF
108.8IL10, IL4, LTA
118.8IL10, IL4, LTA
128.8CD4, IL10, IL4, TNF
138.7CD4, CD8A, IL4, TNF
14
Show member pathways
8.4CD4, IL10, LTA, TNF
158.4CD4, CD8A, IL10, IL4, TNF
16
Show member pathways
8.4CD4, CD8A, IL10, IL4, TNF
17
Show member pathways
8.3IL10, IL4, LTA, TNF
188.3IL10, IL4, LTA, TNF
19
Show member pathways
8.0CD4, IL10, IL4, LTA, TNF
20
Show member pathways
8.0CD4, IL10, IL4, LTA, TNF
217.5CD4, CD8A, IL10, IL4, LTA, TNF
22
Show member pathways
7.5CD4, CD8A, IL10, IL4, LTA, TNF

GO Terms for genes affiliated with Mucocutaneous Leishmaniasis

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Biological processes related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1defense response to protozoanGO:004283210.2IL10, IL4
2receptor biosynthetic processGO:003280010.2IL10, TNF
3type 2 immune responseGO:004209210.2IL10, IL4
4B cell differentiationGO:003018310.2IL10, IL4
5negative regulation of cytokine secretion involved in immune responseGO:000274010.2IL10, TNF
6positive regulation of mononuclear cell migrationGO:007167710.1IL4, TNF
7positive regulation of chemokine biosynthetic processGO:004508010.1IL4, TNF
8negative regulation of endothelial cell apoptotic processGO:200035210.1IL10, IL4
9negative regulation of growth of symbiont in hostGO:004413010.1IL10, TNF
10negative regulation of nitric oxide biosynthetic processGO:004501910.1IL10, IL4
11negative regulation of interleukin-6 productionGO:003271510.0IL10, TNF
12positive regulation of MHC class II biosynthetic processGO:004534810.0IL10, IL4
13positive regulation of calcium-mediated signalingGO:005085010.0CD4, CD8A
14positive regulation of chronic inflammatory response to antigenic stimulusGO:00028769.7LTA, TNF
15response to organic substanceGO:00100339.6IL10, TNF
16positive regulation of interferon-gamma productionGO:00327299.5LTA, TNF
17positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.5IL10, IL4, TNF
18T cell activationGO:00421109.4CD4, CD8A
19response to drugGO:00424938.9IL10, IL4, LTA
20immune responseGO:00069558.8CD4, IL10, IL4, TNF

Molecular functions related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:00150269.7CD4, CD8A

Sources for Mucocutaneous Leishmaniasis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet