MCID: MCC002
MIFTS: 46

Mucocutaneous Leishmaniasis malady

Category: Infectious diseases

Aliases & Classifications for Mucocutaneous Leishmaniasis

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Aliases & Descriptions for Mucocutaneous Leishmaniasis:

Name: Mucocutaneous Leishmaniasis 11 13 68
American Cutaneous Leishmaniasis 11 68
Mucocutaneous Leishmaniasis, American 11
American Mucocutaneous Leishmaniasis 11
 
Cutaneous Leishmaniasis, American 11
New World Cutaneous Leishmaniasis 11
Mucocutaneous Leishmaniasis, 11
Leishmaniasis, Mucocutaneous 39

Classifications:



External Ids:

Disease Ontology11 DOID:9155
ICD1030 B55.2
ICD9CM32 085.5
MeSH39 D007897

Summaries for Mucocutaneous Leishmaniasis

About this section
Disease Ontology:11 A leishmaniasis that involves a chronic inflammatory process involving the nasal, pharyngeal, and laryngeal mucosa, which can lead to extensive tissue destruction, caused by protozoan parasites belonging to the genus Leishmania. The infection is characterized by granulomatous lesion which can destroy upper respiratory tract mucosa.

MalaCards based summary: Mucocutaneous Leishmaniasis, also known as american cutaneous leishmaniasis, is related to leishmaniasis and 12p12.1 microdeletion syndrome. An important gene associated with Mucocutaneous Leishmaniasis is TNF (Tumor Necrosis Factor), and among its related pathways are IL-10 Pathway and African trypanosomiasis. Affiliated tissues include t cells, testes and skin, and related mouse phenotypes are respiratory system and muscle.

Related Diseases for Mucocutaneous Leishmaniasis

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Diseases related to Mucocutaneous Leishmaniasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 230)
idRelated DiseaseScoreTop Affiliating Genes
1leishmaniasis10.8
212p12.1 microdeletion syndrome10.6IL10, TNF
3piepkorn karp hickok syndrome10.6IL10, TNF
4night blindness10.6CD4, TNF
5graft-versus-host disease, protection against10.6IL10, TNF
6fallopian tube endometriosis10.6IL10, TNF
7trichosporonosis10.5CD4, TNF
8linitis plastica10.5CD8A, TNF
9steatorrhea10.5CD4, TNF
10addison's disease10.5IL10, TNF
11suppurative uveitis10.5CD4, TNF
12ocular hypertension10.5CD4, CD8A
13arteriovenous malformation10.5CD4, CD8A
14actinobacillosis10.5CD4, CD8A
15meckel's diverticulitis10.5CD4, CD8A
16endocarditis10.5CD4, TNF
17chronic hiccups10.5CD4, IL10
18scrotum squamous cell carcinoma10.5CD4, CD8A
19hernia of ovary and fallopian tube10.5IL10, TNF
20acute cystitis10.5CD4, CD8A
21folliculitis10.5CD4, CD8A
22cd3gamma deficiency10.5CD4, CD8A
23vaccinia10.5CD4, CD8A
24esophagus carcinoma in situ10.5CD4, CD8A
25intestinal disaccharidase deficiency10.5CD4, CD8A
26nelson syndrome10.5CD4, IL10
27penis basal cell carcinoma10.5CD4, CD8A
28burns10.5IL10, TNF
29extrapulmonary tuberculosis10.5CD4, IL10
30chronic eosinophilic pneumonia10.5CD4, CD8A
31psoriasis10.5CD4, CD8A
32inhalation anthrax10.5CD4, CD8A
33pseudoretinitis pigmentosa10.5IL10, TNF
34thoracic aortic aneurysm10.5CD4, TNF
35total internal ophthalmoplegia10.5CD4, CD8A
36idiopathic central precocious puberty10.5IL10, TNF
37soft palate cancer10.5CD4, CD8A
38agammaglobulinemia, microcephaly, and severe dermatitis10.5CD4, CD8A
39sensorineural hearing loss10.5IL10, TNF
40malignant eyelid melanoma10.5CD4, CD8A
41conventional leiomyosarcoma10.5CD4, CD8A
42gonococcal synovitis10.5IL4, TNF
43psychologic dyspareunia10.5IL10, TNF
44foodborne botulism10.5CD4, TNF
45arachnoiditis10.5CD8A, TNF
46partial third-nerve palsy10.5CD4, CD8A
47mastocytosis cutaneous with short stature conductive hearing loss and microtia10.5IL10, TNF
48hemophagocytic lymphohistiocytosis10.5IL10, TNF
49complex partial epilepsy10.5CD4, CD8A
50lymphocytic colitis10.5IL4, TNF

Graphical network of the top 20 diseases related to Mucocutaneous Leishmaniasis:



Diseases related to mucocutaneous leishmaniasis

Symptoms & Phenotypes for Mucocutaneous Leishmaniasis

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MGI Mouse Phenotypes related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.0IL10, IL4, LTA, TLR3, TNF
2MP:00053698.6IL10, NID1, SCYL1, TLR3, TNF
3MP:00053798.4CD4, CD8A, IL10, IL4, LTA, TLR3
4MP:00053858.1IL10, LTA, NID1, SCYL1, TLR3, TNF
5MP:00053977.5CD4, CD8A, IL10, IL4, LTA, SCYL1
6MP:00053877.5CD4, CD8A, IL10, IL4, LTA, SCYL1
7MP:00107687.5CD4, CD8A, IL10, IL4, LTA, SCYL1
8MP:00053917.4IL10, IL4, LTA, NID1, SCYL1, TNF
9MP:00036316.8CD4, CD8A, IL10, IL4, LTA, NID1

Drugs & Therapeutics for Mucocutaneous Leishmaniasis

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Drugs for Mucocutaneous Leishmaniasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Anti-Infective AgentsPhase 2, Phase 3, Phase 121402
2Antiprotozoal AgentsPhase 2, Phase 3, Phase 11986
3meglumine antimoniatePhase 2, Phase 326
4Antiparasitic AgentsPhase 2, Phase 3, Phase 12127
5
MiltefosineapprovedPhase 2, Phase 13458066-85-63600
Synonyms:
1-Hexadecylphosphorylcholine
2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide, inner salt
3,5-Dioxa-4-phosphaunacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide
4-04-00-01460 (Beilstein Handbook Reference)
58066-85-6
AC1L1GAH
BRN 3690495
Baxter Oncology brand of miltefosine
Baxter brand of miltefosine
C039128
C15H32.C7H17NO4P
CHEBI:125047
CHEMBL125
CID3599
Choline hydroxide, hexadecyl hydrogen phosphate, inner salt
Choline phosphate, hexadecyl ester, hydroxide, inner salt
Choline phosphate, hexadecyl ester, hydroxide, inner salt (6CI)
Choline, hexadecyl hydrogen phosphate, inner salt
D 18506
D-18506
D02494
D18506
Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt
Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, innner salt
H-1850
HDPC
HMS1922D16
HMS2089J15
HePC
Hexadecyl 2-(trimethyl-.lambda.~5~-azanyl)ethyl hydrogen phosphate
 
Hexadecylphosphocholine
Hexadecylphosphorylcholine
I14-7244
IN1227
Impavido
LS-65132
M-7200
Miltefosin
Miltefosin C
Miltefosina
Miltefosina [INN-Spanish]
Miltefosine
Miltefosine (INN)
Miltefosine [INN:BAN]
Miltefosinum
Miltefosinum [INN-Latin]
Miltex
Miltéfosine
MolPort-003-665-519
Monohexadecylphosphocholine
Monohexadecylphosphorylcholine
NCGC00095169-01
NCGC00095169-02
NCGC00095169-03
NSC605583
Prasfarma brand of miltefosine
SPECTRUM1505329
ST51055612
TF-002
UNII-53EY29W7EC
hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
n-Hexadecylphosphorylcholine
6
Miconazoleapproved, investigational, vet_approvedPhase 2, Phase 1362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
7
Coal tarapprovedPhase 21918007-45-2
Synonyms:
 
Coal tars
Tar, coal
8
Amphotericin Bapproved, investigationalPhase 2, Phase 11181397-89-314956, 5280965
Synonyms:
12633-72-6
1397-89-3
30782-62-8
5-18-10-00525 (Beilstein Handbook Reference)
54482-28-9
8055-20-7
AB00513832
ABLC
AC1L1CN2
AC1L24V6
AC1L70KF
AC1L73U6
AC1NQXTD
AC1NTQ32
AC1NUQG4
AC1NY9JC
AC1O7GCZ
AC1O8FQV
AC1O8PFK
AI3-26528
AMPH-B
AMPH-b
Abelcet
Abelecet
AmBisome (TN)
Ambap1397-89-3
Ambisome
Amfotericina B
Amfotericina B [INN-Spanish]
Ampho-Moronal
Amphocin
Amphomoronal
Amphortericin B
Amphotec
Amphotec (TN)
Amphotericin
Amphotericin .BETA.
Amphotericin B
Amphotericin B (JP15/USP/INN)
Amphotericin B Cholesterol Dispersion
Amphotericin B Colloidal Dispersion
Amphotericin B [USAN:INN:JAN]
Amphotericin B, Lipid-based
Amphotericin B, Streptomyces sp.
Amphotericin-B
Amphotericine B
Amphotericine B [INN-French]
Amphotericinum
Amphotericinum B
Amphotericinum B [INN-Latin]
Amphotherizin
Amphotherizin [German]
Amphotéricine B
Amphozone
BIDD:GT0351
BPBio1_000374
BRN 0078342
BSPBio_000340
C-AmB
C06573
C47H73NO17
CCRIS 5963
CHEBI:2682
CHEMBL1200646
CHEMBL267345
CID10533925
CID10629638
CID10677275
CID14956
CID1972
 
CID352546
CID354192
CID5280965
CID5386092
CID5458486
CID5771695
CID6604295
CID6708817
CID6713692
CID9919339
D00203
DB00681
DivK1c_007045
EINECS 215-742-2
Fungilin
Fungisome
Fungisone
Fungizone
Fungizone (TN)
HMS1569A22
HSDB 3008
HSDB 3008 IAB
Halizon
I06-0257
KBio1_001989
KBio2_000551
KBio2_003119
KBio2_005687
KBioGR_002298
KBioSS_000551
LMPK06000002
LNS-AmB
LS-187721
LS-93
Liposomal Amphotericin B
Liposomal amphotericin b
MLS002702966
MolPort-006-392-260
Mysteclin-F
NCGC00014913
NCGC00090808-01
NCGC00098014-01
NCGC00179595-01
NCI527017
NCI60_004288
NCIStruc1_001042
NCIStruc2_000920
NKTR-024
NS 718
NSC 527017
NSC-527017
NSC527017
Prestwick0_000410
Prestwick1_000410
Prestwick2_000410
Prestwick3_000410
Prestwick_721
SMP1_000302
SMR001566780
SPBio_000715
SPBio_002279
ST50999656
SinuNase
SpecPlus_000949
Spectrum2_000818
Spectrum4_001779
Spectrum_000111
UNII-7XU7A7DROE
amophotericin B
amphotericin B liposomal
amphotericin b
9
Pentoxifyllineapproved, investigationalPhase 2996493-05-64740
Synonyms:
1,2,3,6-Tetrahydro-3,7-dimethyl-1-(5-oxohexyl)-2,6-purindion
1-(5-Oxohexyl)-3,7-dimethylxanthine
1-(5-Oxohexyl)theobromine
2a3c
3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxo-hexyl)-3,7-dihydro-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl) xantine
3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)xanthine
3,7-Dimethyl-1-(5-oxohexyl)xantine
3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
5-26-14-00081 (Beilstein Handbook Reference)
6493-05-6
AB00052363
AC1L1IUN
AKOS000541484
Agapurin
Agapurin Retard
Azupentat
BAS 00897429
BB_SC-2111
BIDD:GT0174
BL 191
BL-191
BL191
BPBio1_000167
BRD-K57569181-001-05-1
BRN 0558929
BSPBio_000151
BSPBio_003439
C07424
C13H18N4O3
CAS-1677687
CCRIS 6832
CHEMBL628
CID4740
CPD000035998
D00501
D010431
DB00806
Dimethyloxohexylxanthine
DivK1c_000729
Durapental
EHT 0201
EHT-0201
EHT-201
EHT0201
EINECS 229-374-5
EU-0100936
HMS1568H13
HMS1922E16
HMS2051N06
HMS2090H13
HMS2093G21
HMS502E11
Hemovas
I06-1592
IDI1_000729
IN1161
Ikomio
KBio1_000729
KBio2_001924
KBio2_004492
KBio2_007060
KBio3_002942
KBioGR_000893
KBioSS_001924
LS-149385
 
Lopac-P-1784
Lopac0_000936
MLS000079026
MLS000758298
MLS001201764
MolPort-001-823-263
NCGC00015801-01
NCGC00015801-02
NCGC00015801-04
NCGC00015801-10
NCGC00067069-02
NCGC00067069-03
NCGC00067069-04
NCGC00067069-05
NCGC00178062-01
NCGC00178062-02
NINDS_000729
NSC 637086
NSC637086
Oxpentifylline
P 1784
PDSP1_001015
PDSP2_000999
PENTOXYPHYLINE
PNX
Pentoxifilina
Pentoxifilina [INN-Spanish]
Pentoxifyllin
Pentoxifylline
Pentoxifylline (JAN/USP/INN)
Pentoxifylline [USAN:INN:JAN]
Pentoxifyllinum
Pentoxifyllinum [INN-Latin]
Pentoxil
Pentoxil (TN)
Pentoxiphyllin
Pentoxiphylline
Pentoxiphyllium
Pentoxyfylline
Pentoxyphyllin
Pentoxyphylline
Prestwick0_000196
Prestwick1_000196
Prestwick2_000196
Prestwick3_000196
Prestwick_608
Px
Ralofect
Rentylin
SAM001247011
SMR000035998
SPBio_001221
SPBio_002072
SPECTRUM1503611
SR-01000075641-4
STK177321
Spectrum2_001181
Spectrum3_001820
Spectrum4_000227
Spectrum5_001161
Spectrum_001444
Torental
Trental
Trental (TN)
UNII-SD6QCT3TSU
Vasofirin
Vazofirin
ZINC01530776
cis-9-Octadecenoyl coenzyme A
pentoxifylline
10Liposomal amphotericin BPhase 2, Phase 1118
11AnthelminticsPhase 2, Phase 1431
12Antimony Sodium GluconatePhase 2, Phase 116
13Antifungal AgentsPhase 2, Phase 13615
14Vasodilator AgentsPhase 23438
15Radiation-Protective AgentsPhase 2466
16Protective AgentsPhase 27190
17Platelet Aggregation InhibitorsPhase 22419
18Phosphodiesterase InhibitorsPhase 21254
19AntioxidantsPhase 22928
20VaccinesPhase 16428

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Low Antimonial Dosage in American Mucosal LeishmaniasisRecruitingNCT01301937Phase 2, Phase 3
2Clinical Trial of Miltefosine to Treat Mucosal LeishmaniasisCompletedNCT01377974Phase 2
3Miltefosine to Treat Mucocutaneous LeishmaniasisCompletedNCT01050907Phase 2
4Miltefosine for Mucosal LeishmaniasisCompletedNCT00373776Phase 1, Phase 2
5Miltefosine (Long Course) for Bolivian Mucosal LeishmaniasisCompletedNCT00373568Phase 1, Phase 2
6Sodium Stibogluconate Treatment of LeishmaniasisCompletedNCT00662012Phase 2
7Miltefosine to Treat Cutaneous Leishmaniasis in BoliviaCompletedNCT00233545Phase 2
8The Association of Miltefosine and Pentoxifylline to Treat Mucosal Leishmaniasis: A Clinical Trial in BrazilRecruitingNCT02530697Phase 2
9Use of Sodium Stibogluconate as a Treatment for LeishmaniasisEnrolling by invitationNCT00657618Phase 1, Phase 2
10Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Mucosal LeishmaniasisCompletedNCT00111514Phase 1
11Diagnosis and Treatment of Leishmanial InfectionsRecruitingNCT00344188
12Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World LeishmaniasisAvailableNCT00508963
13Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous LeishmaniasisNot yet recruitingNCT02429518
14Spermiogram Assessment in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous LeishmaniasisNot yet recruitingNCT02431429

Search NIH Clinical Center for Mucocutaneous Leishmaniasis


Cochrane evidence based reviews: leishmaniasis, mucocutaneous

Genetic Tests for Mucocutaneous Leishmaniasis

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Anatomical Context for Mucocutaneous Leishmaniasis

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MalaCards organs/tissues related to Mucocutaneous Leishmaniasis:

36
T cells, Testes, Skin, Monocytes

Publications for Mucocutaneous Leishmaniasis

About this section

Articles related to Mucocutaneous Leishmaniasis:

(show top 50)    (show all 144)
idTitleAuthorsYear
1
Mucocutaneous leishmaniasis. (26994882)
2016
2
Unusual presentation of mucocutaneous leishmaniasis in HIV-infected patient. (27890957)
2016
3
Mucocutaneous leishmaniasis with marked facial disfigurement. (27643545)
2016
4
Cutaneous and mucocutaneous leishmaniasis: Differential diagnosis, diagnosis, histopathology, and management. (26568336)
2015
5
Mucocutaneous leishmaniasis in an 11-year-old girl with ataxia telangectasia - case report. (25661291)
2015
6
Immune response to Leishmania antigens in an AIDS patient with mucocutaneous leishmaniasis as a manifestation of immune reconstitution inflammatory syndrome (IRIS): a case report. (25645330)
2015
7
Accuracy of mucocutaneous leishmaniasis diagnosis using polymerase chain reaction: systematic literature review and meta-analysis. (25830540)
2015
8
Mucocutaneous leishmaniasis of the nose: a case report. (26513953)
2015
9
Cutaneous and mucocutaneous leishmaniasis: Clinical perspectives. (26568335)
2015
10
Mucocutaneous leishmaniasis must be included in the differential diagnosis of midline destructive disease: two case reports. (25442251)
2015
11
Mucocutaneous leishmaniasis caused by Leishmania infantum var Lombardi in an immunocompetent patient, Spain. (25559703)
2015
12
Accuracy of mucocutaneous leishmaniasis diagnosis using polymerase chain reaction: systematic literature review and meta-analysis. (25946238)
2015
13
Short communication: mucocutaneous leishmaniasis in HIV-related immune reconstitution syndrome. (26154873)
2015
14
Polymerase chain reaction-miniexon: a promising diagnostic method for mucocutaneous leishmaniasis. (26452681)
2015
15
Mucocutaneous Leishmaniasis/HIV Coinfection Presented as a Diffuse Desquamative Rash. (25548691)
2014
16
Mucocutaneous leishmaniasis caused by Leishmania donovani infection in an Indian man. (25557311)
2014
17
A case of mucocutaneous leishmaniasis diagnosed by serology. (25041360)
2014
18
Ear, nose and throat manifestations of mucocutaneous Leishmaniasis: a literature review. (24897964)
2014
19
Mucocutaneous leishmaniasis as presentation of HIV infection in Sardinia, insular Italy. (24126182)
2014
20
Mucocutaneous leishmaniasis: accuracy and molecular validation of noninvasive procedures in a L. (V.) braziliensis-endemic area. (24923211)
2014
21
Cutaneous and mucocutaneous leishmaniasis resembling borderline-tuberculoid leprosy: a new clinical presentation? (22434112)
2013
22
First molecular-based detection of mucocutaneous leishmaniasis caused by Leishmania major in Iran. (23669431)
2013
23
Mucocutaneous leishmaniasis: mucosal manifestations in an endemic country. (23867693)
2013
24
Interventions for American cutaneous and mucocutaneous leishmaniasis: a systematic review update. (23637917)
2013
25
Mucocutaneous leishmaniasis: knowledge, attitudes, and practices among paraguayan communities, patients, and health professionals. (23690792)
2013
26
Phosphatidylserine exposure and surface sugars in two Leishmania (Viannia) braziliensis strains involved in cutaneous and mucocutaneous leishmaniasis. (23148292)
2013
27
Therapeutic options for old world cutaneous leishmaniasis and new world cutaneous and mucocutaneous leishmaniasis. (24170665)
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Primary lesion of mucocutaneous leishmaniasis simulating external otitis. (23108835)
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Cutaneous and mucocutaneous leishmaniasis. (22632640)
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Accurate and rapid species typing from cutaneous and mucocutaneous leishmaniasis lesions of the New World. (22819605)
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Mucocutaneous leishmaniasis in a patient treated with anti-TNF-I+ therapy. (22427411)
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Mucocutaneous Leishmaniasis: clinical markers in presumptive diagnosis. (21739015)
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Diffuse mucocutaneous leishmaniasis. (22479746)
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Polymerase chain reaction detection of Leishmania kDNA from the urine of Peruvian patients with cutaneous and mucocutaneous leishmaniasis. (21460009)
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Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis. (21311023)
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Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis. (20377337)
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Treatment strategies for mucocutaneous leishmaniasis. (20606970)
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Comment on: Cutaneous and mucocutaneous leishmaniasis in Tigray, northern Ethiopia: clinical aspects and therapeutic concerns. (19836815)
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Mucocutaneous leishmaniasis masquerading as Wegener granulomatosis. (20375822)
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A chronic mutilating rhinopathy with a delayed diagnosis of mucocutaneous leishmaniasis. (20465699)
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Cutaneous and mucocutaneous leishmaniasis: emerging therapies and progress in disease management. (20163267)
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Interventions for American cutaneous and mucocutaneous leishmaniasis. (19370612)
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Cutaneous and mucocutaneous leishmaniasis in Tigray, northern Ethiopia: clinical aspects and therapeutic concerns. (19356780)
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Cutaneous and mucocutaneous leishmaniasis. (19889134)
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The value of the otorhinolaryngologic exam in correct mucocutaneous leishmaniasis diagnosis. (19706900)
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Successful diagnosis and treatment 50 years after exposure: is mucocutaneous leishmaniasis still a neglected differential diagnosis? (19090806)
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Cytokine profile in Montenegro skin test of patients with localized cutaneous and mucocutaneous leishmaniasis. (19082374)
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Mucocutaneous leishmaniasis treated with liposomal amphotericin B. (18368279)
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Multiple hybrid genotypes of Leishmania (viannia) in a focus of mucocutaneous Leishmaniasis. (17360886)
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Parenteral aminosidine is not effective for Peruvian mucocutaneous leishmaniasis. (17556623)
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Variations for Mucocutaneous Leishmaniasis

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Expression for genes affiliated with Mucocutaneous Leishmaniasis

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Search GEO for disease gene expression data for Mucocutaneous Leishmaniasis.

Pathways for genes affiliated with Mucocutaneous Leishmaniasis

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Pathways related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

(show all 25)
idSuper pathwaysScoreTop Affiliating Genes
19.8IL10, TNF
29.8IL10, TNF
39.7CD4, CD8A
4
Show member pathways
9.3IL10, IL4, TNF
59.3CD4, IL10, IL4
6
Show member pathways
9.3CD4, CD8A, IL4
7
Show member pathways
9.2CD4, IL4, TLR3
89.1IL10, IL4, LTA
99.1IL10, IL4, LTA
109.0CD4, CD8A, IL10, TNF
11
Show member pathways
9.0CD4, IL10, IL4, TNF
129.0CD4, IL10, IL4, TNF
138.9CD4, CD8A, IL4, TNF
148.8IL10, IL4, LTA, TNF
158.8IL10, IL4, LTA, TNF
16
Show member pathways
8.8IL10, IL4, LTA, TNF
17
Show member pathways
8.7IL4, LTA, TLR3, TNF
188.6CD4, CD8A, IL10, IL4, TNF
19
Show member pathways
8.6CD4, CD8A, IL10, IL4, TNF
20
Show member pathways
8.5CD4, IL10, IL4, LTA, TNF
21
Show member pathways
8.4CD4, IL10, LTA, TLR3, TNF
228.0CD4, CD8A, IL10, IL4, TLR3, TNF
238.0CD4, CD8A, IL10, IL4, LTA, TNF
24
Show member pathways
8.0CD4, CD8A, IL10, IL4, LTA, TNF
25
Show member pathways
7.9CD4, IL10, IL4, LTA, TLR3, TNF

GO Terms for genes affiliated with Mucocutaneous Leishmaniasis

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Cellular components related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor complexGO:00421019.7CD4, CD8A
2cell surfaceGO:00099869.5CD4, CD8A, TLR3, TNF
3external side of plasma membraneGO:00098979.3CD4, CD8A, IL4, TNF

Biological processes related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

(show all 26)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of cytokine secretion involved in immune responseGO:000274010.4IL10, TNF
2negative regulation of interleukin-6 productionGO:003271510.4IL10, TNF
3positive regulation of cytokine secretionGO:005071510.4IL10, TNF
4positive regulation of calcium-mediated signalingGO:005085010.4CD4, CD8A
5defense response to protozoanGO:004283210.3IL10, IL4
6positive regulation of mononuclear cell migrationGO:007167710.3IL4, TNF
7negative regulation of endothelial cell apoptotic processGO:200035210.3IL10, IL4
8necroptotic signaling pathwayGO:009752710.3TLR3, TNF
9negative regulation of nitric oxide biosynthetic processGO:004501910.3IL10, IL4
10positive regulation of chemokine productionGO:003272210.3TLR3, TNF
11positive regulation of chronic inflammatory response to antigenic stimulusGO:000287610.3LTA, TNF
12positive regulation of MHC class II biosynthetic processGO:004534810.3IL10, IL4
13positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292510.3LTA, TNF
14positive regulation of interleukin-8 productionGO:003275710.3TLR3, TNF
15positive regulation of NF-kappaB import into nucleusGO:004234610.2TLR3, TNF
16microglial cell activationGO:000177410.2IL4, TLR3
17negative regulation of osteoclast differentiationGO:004567110.1IL4, TLR3
18receptor biosynthetic processGO:003280010.0IL10, TNF
19defense response to bacteriumGO:004274210.0IL10, TLR3, TNF
20negative regulation of growth of symbiont in hostGO:00441309.9IL10, LTA, TNF
21positive regulation of chemokine biosynthetic processGO:00450809.8IL4, TLR3, TNF
22regulation of isotype switchingGO:00451919.8IL10, IL4
23positive regulation of protein phosphorylationGO:00019349.7IL4, TLR3, TNF
24type 2 immune responseGO:00420929.6IL10, IL4
25positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.6IL10, IL4, TNF
26immune responseGO:00069559.6CD4, CD8A, IL10, IL4

Molecular functions related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:001502610.3CD4, CD8A
2tumor necrosis factor receptor bindingGO:00051649.6LTA, TNF
3cytokine activityGO:00051259.2IL10, IL4, LTA, TNF

Sources for Mucocutaneous Leishmaniasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet