MCID: MCC002
MIFTS: 46

Mucocutaneous Leishmaniasis malady

Category: Infectious diseases

Aliases & Classifications for Mucocutaneous Leishmaniasis

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Aliases & Descriptions for Mucocutaneous Leishmaniasis:

Name: Mucocutaneous Leishmaniasis 11 13 67
American Cutaneous Leishmaniasis 11 67
Mucocutaneous Leishmaniasis, American 11
American Mucocutaneous Leishmaniasis 11
 
Cutaneous Leishmaniasis, American 11
New World Cutaneous Leishmaniasis 11
Mucocutaneous Leishmaniasis, 11
Leishmaniasis, Mucocutaneous 38

Classifications:



External Ids:

Disease Ontology11 DOID:9155
ICD1029 B55.2
ICD9CM31 085.5
MeSH38 D007897

Summaries for Mucocutaneous Leishmaniasis

About this section
Disease Ontology:11 A leishmaniasis that involves a chronic inflammatory process involving the nasal, pharyngeal, and laryngeal mucosa, which can lead to extensive tissue destruction, caused by protozoan parasites belonging to the genus Leishmania. The infection is characterized by granulomatous lesion which can destroy upper respiratory tract mucosa.

MalaCards based summary: Mucocutaneous Leishmaniasis, also known as american cutaneous leishmaniasis, is related to leishmaniasis and 12p12.1 microdeletion syndrome. An important gene associated with Mucocutaneous Leishmaniasis is TNF (Tumor Necrosis Factor), and among its related pathways are IL-10 Pathway and African trypanosomiasis. Affiliated tissues include t cells, testes and skin, and related mouse phenotypes are respiratory system and muscle.

Related Diseases for Mucocutaneous Leishmaniasis

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Diseases related to Mucocutaneous Leishmaniasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 230)
idRelated DiseaseScoreTop Affiliating Genes
1leishmaniasis10.8
212p12.1 microdeletion syndrome10.6IL10, TNF
3piepkorn karp hickok syndrome10.6IL10, TNF
4night blindness10.6CD4, TNF
5graft-versus-host disease, protection against10.6IL10, TNF
6fallopian tube endometriosis10.6IL10, TNF
7trichosporonosis10.5CD4, TNF
8linitis plastica10.5CD8A, TNF
9steatorrhea10.5CD4, TNF
10addison's disease10.5IL10, TNF
11suppurative uveitis10.5CD4, TNF
12ocular hypertension10.5CD4, CD8A
13arteriovenous malformation10.5CD4, CD8A
14actinobacillosis10.5CD4, CD8A
15meckel's diverticulitis10.5CD4, CD8A
16endocarditis10.5CD4, TNF
17chronic hiccups10.5CD4, IL10
18scrotum squamous cell carcinoma10.5CD4, CD8A
19hernia of ovary and fallopian tube10.5IL10, TNF
20acute cystitis10.5CD4, CD8A
21folliculitis10.5CD4, CD8A
22cd3gamma deficiency10.5CD4, CD8A
23vaccinia10.5CD4, CD8A
24esophagus carcinoma in situ10.5CD4, CD8A
25intestinal disaccharidase deficiency10.5CD4, CD8A
26nelson syndrome10.5CD4, IL10
27penis basal cell carcinoma10.5CD4, CD8A
28burns10.5IL10, TNF
29extrapulmonary tuberculosis10.5CD4, IL10
30chronic eosinophilic pneumonia10.5CD4, CD8A
31psoriasis10.5CD4, CD8A
32inhalation anthrax10.5CD4, CD8A
33pseudoretinitis pigmentosa10.5IL10, TNF
34thoracic aortic aneurysm10.5CD4, TNF
35total internal ophthalmoplegia10.5CD4, CD8A
36idiopathic central precocious puberty10.5IL10, TNF
37soft palate cancer10.5CD4, CD8A
38agammaglobulinemia, microcephaly, and severe dermatitis10.5CD4, CD8A
39sensorineural hearing loss10.5IL10, TNF
40malignant eyelid melanoma10.5CD4, CD8A
41conventional leiomyosarcoma10.5CD4, CD8A
42gonococcal synovitis10.5IL4, TNF
43psychologic dyspareunia10.5IL10, TNF
44foodborne botulism10.5CD4, TNF
45arachnoiditis10.5CD8A, TNF
46partial third-nerve palsy10.5CD4, CD8A
47mastocytosis cutaneous with short stature conductive hearing loss and microtia10.5IL10, TNF
48hemophagocytic lymphohistiocytosis10.5IL10, TNF
49complex partial epilepsy10.5CD4, CD8A
50lymphocytic colitis10.5IL4, TNF

Graphical network of the top 20 diseases related to Mucocutaneous Leishmaniasis:



Diseases related to mucocutaneous leishmaniasis

Symptoms for Mucocutaneous Leishmaniasis

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Drugs & Therapeutics for Mucocutaneous Leishmaniasis

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Drugs for Mucocutaneous Leishmaniasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Anti-Infective AgentsPhase 2, Phase 3, Phase 121402
2Antiprotozoal AgentsPhase 2, Phase 3, Phase 11986
3meglumine antimoniatePhase 2, Phase 326
4Antiparasitic AgentsPhase 2, Phase 3, Phase 12127
5
MiltefosineapprovedPhase 2, Phase 13458066-85-63600
Synonyms:
1-Hexadecylphosphorylcholine
2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide, inner salt
3,5-Dioxa-4-phosphaunacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide
4-04-00-01460 (Beilstein Handbook Reference)
58066-85-6
AC1L1GAH
BRN 3690495
Baxter Oncology brand of miltefosine
Baxter brand of miltefosine
C039128
C15H32.C7H17NO4P
CHEBI:125047
CHEMBL125
CID3599
Choline hydroxide, hexadecyl hydrogen phosphate, inner salt
Choline phosphate, hexadecyl ester, hydroxide, inner salt
Choline phosphate, hexadecyl ester, hydroxide, inner salt (6CI)
Choline, hexadecyl hydrogen phosphate, inner salt
D 18506
D-18506
D02494
D18506
Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt
Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, innner salt
H-1850
HDPC
HMS1922D16
HMS2089J15
HePC
Hexadecyl 2-(trimethyl-.lambda.~5~-azanyl)ethyl hydrogen phosphate
 
Hexadecylphosphocholine
Hexadecylphosphorylcholine
I14-7244
IN1227
Impavido
LS-65132
M-7200
Miltefosin
Miltefosin C
Miltefosina
Miltefosina [INN-Spanish]
Miltefosine
Miltefosine (INN)
Miltefosine [INN:BAN]
Miltefosinum
Miltefosinum [INN-Latin]
Miltex
Miltéfosine
MolPort-003-665-519
Monohexadecylphosphocholine
Monohexadecylphosphorylcholine
NCGC00095169-01
NCGC00095169-02
NCGC00095169-03
NSC605583
Prasfarma brand of miltefosine
SPECTRUM1505329
ST51055612
TF-002
UNII-53EY29W7EC
hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
n-Hexadecylphosphorylcholine
6
Miconazoleapproved, investigational, vet_approvedPhase 2, Phase 1362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
7
Coal tarapprovedPhase 21918007-45-2
Synonyms:
 
Coal tars
Tar, coal
8
Amphotericin Bapproved, investigationalPhase 2, Phase 11181397-89-314956, 5280965
Synonyms:
12633-72-6
1397-89-3
30782-62-8
5-18-10-00525 (Beilstein Handbook Reference)
54482-28-9
8055-20-7
AB00513832
ABLC
AC1L1CN2
AC1L24V6
AC1L70KF
AC1L73U6
AC1NQXTD
AC1NTQ32
AC1NUQG4
AC1NY9JC
AC1O7GCZ
AC1O8FQV
AC1O8PFK
AI3-26528
AMPH-B
AMPH-b
Abelcet
Abelecet
AmBisome (TN)
Ambap1397-89-3
Ambisome
Amfotericina B
Amfotericina B [INN-Spanish]
Ampho-Moronal
Amphocin
Amphomoronal
Amphortericin B
Amphotec
Amphotec (TN)
Amphotericin
Amphotericin .BETA.
Amphotericin B
Amphotericin B (JP15/USP/INN)
Amphotericin B Cholesterol Dispersion
Amphotericin B Colloidal Dispersion
Amphotericin B [USAN:INN:JAN]
Amphotericin B, Lipid-based
Amphotericin B, Streptomyces sp.
Amphotericin-B
Amphotericine B
Amphotericine B [INN-French]
Amphotericinum
Amphotericinum B
Amphotericinum B [INN-Latin]
Amphotherizin
Amphotherizin [German]
Amphotéricine B
Amphozone
BIDD:GT0351
BPBio1_000374
BRN 0078342
BSPBio_000340
C-AmB
C06573
C47H73NO17
CCRIS 5963
CHEBI:2682
CHEMBL1200646
CHEMBL267345
CID10533925
CID10629638
CID10677275
CID14956
CID1972
 
CID352546
CID354192
CID5280965
CID5386092
CID5458486
CID5771695
CID6604295
CID6708817
CID6713692
CID9919339
D00203
DB00681
DivK1c_007045
EINECS 215-742-2
Fungilin
Fungisome
Fungisone
Fungizone
Fungizone (TN)
HMS1569A22
HSDB 3008
HSDB 3008 IAB
Halizon
I06-0257
KBio1_001989
KBio2_000551
KBio2_003119
KBio2_005687
KBioGR_002298
KBioSS_000551
LMPK06000002
LNS-AmB
LS-187721
LS-93
Liposomal Amphotericin B
Liposomal amphotericin b
MLS002702966
MolPort-006-392-260
Mysteclin-F
NCGC00014913
NCGC00090808-01
NCGC00098014-01
NCGC00179595-01
NCI527017
NCI60_004288
NCIStruc1_001042
NCIStruc2_000920
NKTR-024
NS 718
NSC 527017
NSC-527017
NSC527017
Prestwick0_000410
Prestwick1_000410
Prestwick2_000410
Prestwick3_000410
Prestwick_721
SMP1_000302
SMR001566780
SPBio_000715
SPBio_002279
ST50999656
SinuNase
SpecPlus_000949
Spectrum2_000818
Spectrum4_001779
Spectrum_000111
UNII-7XU7A7DROE
amophotericin B
amphotericin B liposomal
amphotericin b
9
Pentoxifyllineapproved, investigationalPhase 2996493-05-64740
Synonyms:
1,2,3,6-Tetrahydro-3,7-dimethyl-1-(5-oxohexyl)-2,6-purindion
1-(5-Oxohexyl)-3,7-dimethylxanthine
1-(5-Oxohexyl)theobromine
2a3c
3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxo-hexyl)-3,7-dihydro-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl) xantine
3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)xanthine
3,7-Dimethyl-1-(5-oxohexyl)xantine
3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
5-26-14-00081 (Beilstein Handbook Reference)
6493-05-6
AB00052363
AC1L1IUN
AKOS000541484
Agapurin
Agapurin Retard
Azupentat
BAS 00897429
BB_SC-2111
BIDD:GT0174
BL 191
BL-191
BL191
BPBio1_000167
BRD-K57569181-001-05-1
BRN 0558929
BSPBio_000151
BSPBio_003439
C07424
C13H18N4O3
CAS-1677687
CCRIS 6832
CHEMBL628
CID4740
CPD000035998
D00501
D010431
DB00806
Dimethyloxohexylxanthine
DivK1c_000729
Durapental
EHT 0201
EHT-0201
EHT-201
EHT0201
EINECS 229-374-5
EU-0100936
HMS1568H13
HMS1922E16
HMS2051N06
HMS2090H13
HMS2093G21
HMS502E11
Hemovas
I06-1592
IDI1_000729
IN1161
Ikomio
KBio1_000729
KBio2_001924
KBio2_004492
KBio2_007060
KBio3_002942
KBioGR_000893
KBioSS_001924
LS-149385
 
Lopac-P-1784
Lopac0_000936
MLS000079026
MLS000758298
MLS001201764
MolPort-001-823-263
NCGC00015801-01
NCGC00015801-02
NCGC00015801-04
NCGC00015801-10
NCGC00067069-02
NCGC00067069-03
NCGC00067069-04
NCGC00067069-05
NCGC00178062-01
NCGC00178062-02
NINDS_000729
NSC 637086
NSC637086
Oxpentifylline
P 1784
PDSP1_001015
PDSP2_000999
PENTOXYPHYLINE
PNX
Pentoxifilina
Pentoxifilina [INN-Spanish]
Pentoxifyllin
Pentoxifylline
Pentoxifylline (JAN/USP/INN)
Pentoxifylline [USAN:INN:JAN]
Pentoxifyllinum
Pentoxifyllinum [INN-Latin]
Pentoxil
Pentoxil (TN)
Pentoxiphyllin
Pentoxiphylline
Pentoxiphyllium
Pentoxyfylline
Pentoxyphyllin
Pentoxyphylline
Prestwick0_000196
Prestwick1_000196
Prestwick2_000196
Prestwick3_000196
Prestwick_608
Px
Ralofect
Rentylin
SAM001247011
SMR000035998
SPBio_001221
SPBio_002072
SPECTRUM1503611
SR-01000075641-4
STK177321
Spectrum2_001181
Spectrum3_001820
Spectrum4_000227
Spectrum5_001161
Spectrum_001444
Torental
Trental
Trental (TN)
UNII-SD6QCT3TSU
Vasofirin
Vazofirin
ZINC01530776
cis-9-Octadecenoyl coenzyme A
pentoxifylline
10Liposomal amphotericin BPhase 2, Phase 1118
11AnthelminticsPhase 2, Phase 1431
12Antimony Sodium GluconatePhase 2, Phase 116
13Antifungal AgentsPhase 2, Phase 13615
14Vasodilator AgentsPhase 23438
15Radiation-Protective AgentsPhase 2466
16Protective AgentsPhase 27190
17Platelet Aggregation InhibitorsPhase 22419
18Phosphodiesterase InhibitorsPhase 21254
19AntioxidantsPhase 22928
20VaccinesPhase 16428

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Low Antimonial Dosage in American Mucosal LeishmaniasisRecruitingNCT01301937Phase 2, Phase 3
2Clinical Trial of Miltefosine to Treat Mucosal LeishmaniasisCompletedNCT01377974Phase 2
3Miltefosine to Treat Mucocutaneous LeishmaniasisCompletedNCT01050907Phase 2
4Miltefosine for Mucosal LeishmaniasisCompletedNCT00373776Phase 1, Phase 2
5Miltefosine (Long Course) for Bolivian Mucosal LeishmaniasisCompletedNCT00373568Phase 1, Phase 2
6Sodium Stibogluconate Treatment of LeishmaniasisCompletedNCT00662012Phase 2
7Miltefosine to Treat Cutaneous Leishmaniasis in BoliviaCompletedNCT00233545Phase 2
8The Association of Miltefosine and Pentoxifylline to Treat Mucosal Leishmaniasis: A Clinical Trial in BrazilRecruitingNCT02530697Phase 2
9Use of Sodium Stibogluconate as a Treatment for LeishmaniasisEnrolling by invitationNCT00657618Phase 1, Phase 2
10Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Mucosal LeishmaniasisCompletedNCT00111514Phase 1
11Diagnosis and Treatment of Leishmanial InfectionsRecruitingNCT00344188
12Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World LeishmaniasisAvailableNCT00508963
13Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous LeishmaniasisNot yet recruitingNCT02429518
14Spermiogram Assessment in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous LeishmaniasisNot yet recruitingNCT02431429

Search NIH Clinical Center for Mucocutaneous Leishmaniasis


Cochrane evidence based reviews: leishmaniasis, mucocutaneous

Genetic Tests for Mucocutaneous Leishmaniasis

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Anatomical Context for Mucocutaneous Leishmaniasis

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MalaCards organs/tissues related to Mucocutaneous Leishmaniasis:

35
T cells, Testes, Skin, Monocytes

Animal Models for Mucocutaneous Leishmaniasis or affiliated genes

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MGI Mouse Phenotypes related to Mucocutaneous Leishmaniasis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.0IL10, IL4, LTA, TLR3, TNF
2MP:00053698.6IL10, NID1, SCYL1, TLR3, TNF
3MP:00053798.4CD4, CD8A, IL10, IL4, LTA, TLR3
4MP:00053858.1IL10, LTA, NID1, SCYL1, TLR3, TNF
5MP:00053977.5CD4, CD8A, IL10, IL4, LTA, SCYL1
6MP:00053877.5CD4, CD8A, IL10, IL4, LTA, SCYL1
7MP:00107687.5CD4, CD8A, IL10, IL4, LTA, SCYL1
8MP:00053917.4IL10, IL4, LTA, NID1, SCYL1, TNF
9MP:00036316.8CD4, CD8A, IL10, IL4, LTA, NID1

Publications for Mucocutaneous Leishmaniasis

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Articles related to Mucocutaneous Leishmaniasis:

(show top 50)    (show all 144)
idTitleAuthorsYear
1
Mucocutaneous leishmaniasis. (26994882)
2016
2
Unusual presentation of mucocutaneous leishmaniasis in HIV-infected patient. (27890957)
2016
3
Cutaneous and mucocutaneous leishmaniasis: Differential diagnosis, diagnosis, histopathology, and management. (26568336)
2015
4
Mucocutaneous leishmaniasis in an 11-year-old girl with ataxia telangectasia - case report. (25661291)
2015
5
Immune response to Leishmania antigens in an AIDS patient with mucocutaneous leishmaniasis as a manifestation of immune reconstitution inflammatory syndrome (IRIS): a case report. (25645330)
2015
6
Mucocutaneous Leishmaniasis/HIV Coinfection Presented as a Diffuse Desquamative Rash. (25548691)
2014
7
Cutaneous and mucocutaneous leishmaniasis resembling borderline-tuberculoid leprosy: a new clinical presentation? (22434112)
2013
8
Primary lesion of mucocutaneous leishmaniasis simulating external otitis. (23108835)
2012
9
Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis. (20377337)
2010
10
Interventions for American cutaneous and mucocutaneous leishmaniasis. (19370612)
2009
11
Successful diagnosis and treatment 50 years after exposure: is mucocutaneous leishmaniasis still a neglected differential diagnosis? (19090806)
2008
12
Cytokine profile in Montenegro skin test of patients with localized cutaneous and mucocutaneous leishmaniasis. (19082374)
2008
13
Mucocutaneous leishmaniasis treated with liposomal amphotericin B. (18368279)
2008
14
Multiple hybrid genotypes of Leishmania (viannia) in a focus of mucocutaneous Leishmaniasis. (17360886)
2007
15
Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony. (17119754)
2006
16
Mucocutaneous leishmaniasis: an imported infection among travellers to central and South America. (15472268)
2004
17
Disseminated mucocutaneous leishmaniasis resulting from chronic use of corticosteroid. (12956682)
2003
18
Chronic dacryocystitis in American mucocutaneous leishmaniasis. (11206745)
2001
19
Atypical mucocutaneous leishmaniasis caused by Leishmania braziliensis in an acquired immunodeficiency syndrome patient: T-cell responses and remission of lesions associated with antigen immunotherapy. (10446016)
1999
20
Risk factors for onset of cutaneous and mucocutaneous leishmaniasis in Bolivia. (9242324)
1997
21
Cutaneous and mucocutaneous leishmaniasis. (8620680)
1996
22
Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis. (7595196)
1995
23
T-cell responses to infected autologous monocytes in patients with cutaneous and mucocutaneous leishmaniasis. (7496967)
1994
24
American cutaneous and mucocutaneous leishmaniasis (tegumentary): a diagnostic challenge. (1492379)
1992
25
Electrocardiographic alterations during treatment of mucocutaneous leishmaniasis with meglumine antimoniate and allopurinol. (1566297)
1992
26
Evaluation of the histopathological classifications of American cutaneous and mucocutaneous leishmaniasis. (1842401)
1991
27
Prevalence of mucocutaneous leishmaniasis in littoral Bahia, Brazil. (2389315)
1990
28
Histological analysis and the pathogenesis of mucocutaneous leishmaniasis. (2614573)
1989
29
Evaluation of serological diagnostic indices for mucocutaneous leishmaniasis: immunofluorescence tests and enzyme-linked immunoassays for IgG, IgM and IgA antibodies. (2699277)
1989
30
Evaluation of a skin test on the canine mucocutaneous leishmaniasis diagnosis. (3078346)
1988
31
Frequency of Leishmania-reactive T cells in lesions of American mucocutaneous leishmaniasis (AMCL) patients. Its relevance in the process of healing or aggravation of the disease. (3267032)
1988
32
Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis). (2687621)
1988
33
Peroxidase antibody test for mucocutaneous leishmaniasis serology. Performance indexes and comparison with a fluorescent antibody test. (3075341)
1988
34
Identification and purification of a 72 kDa antigen of Leishmania braziliensis braziliensis present on the surface and in the cytoplasm of the promastigotes and its specific recognition by sera from mucocutaneous leishmaniasis patients. (3253506)
1988
35
Diagnosis of cutaneous and mucocutaneous leishmaniasis in Colombia: a comparison of seven methods. (2437815)
1987
36
A focus of mucocutaneous leishmaniasis in TrA-s BraAsos, Bahia, Brazil: characterization and identification of Leishmania stocks isolated from man and dogs. (3909556)
1985
37
Identification of human stocks of Leishmania spp. isolated from patients with mucocutaneous leishmaniasis in TrA-s BraAsos, Bahia, Brazil. (6506171)
1984
38
Specific IgE antibodies to Leishmania braziliensis in patients with mucocutaneous leishmaniasis. (6625531)
1983
39
Immunoenzymatic assy (ELISA) in mucocutaneous leishmaniasis, kala-azar, and Chagas' disease: an epimastigote Trypanosoma cruzi antigen able to distinguish between anti-Trypanosoma and anti-Leishmania antibodies. (6792937)
1981
40
Parasitologic and immunologic diagnosis of American (mucocutaneous) leishmaniasis. (7030439)
1981
41
A histological classification of mucocutaneous leishmaniasis in Brazil and its clinical evaluation. (7445048)
1980
42
Interstitial keratitis caused by American (mucocutaneous) leishmaniasis. (434070)
1979
43
Failure of metronidazole treatment in Ethiopian mucocutaneous leishmaniasis. (708614)
1978
44
Use of amphotericin B in mucocutaneous leishmaniasis. (933229)
1976
45
Leishmaniasis in Brazil: X. Some observations of intradermal reactions to different trypanosomatid antigens of patients suffering from cutaneous and mucocutaneous leishmaniasis. (52214)
1975
46
Mucocutaneous leishmaniasis in guinea-pigs inoculated intravenously with Leishmania enriettii. Preliminary report. (1182080)
1975
47
THE HUMAN TRYPANOSOMATIDAE. IV. CUTANEOUS AND MUCOCUTANEOUS LEISHMANIASIS. (14083450)
1963
48
The treatment of American (mucocutaneous) leishmaniasis with amphotericin B. (13745957)
1960
49
Leishmaniasis; report of a case of mucocutaneous leishmaniasis diagnosed in Sweden. (13180240)
1954
50
Mucocutaneous leishmaniasis in Kenya, with a note on penicillin treatment. (20243886)
1947

Variations for Mucocutaneous Leishmaniasis

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Expression for genes affiliated with Mucocutaneous Leishmaniasis

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Search GEO for disease gene expression data for Mucocutaneous Leishmaniasis.

Pathways for genes affiliated with Mucocutaneous Leishmaniasis

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Pathways related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

(show all 25)
idSuper pathwaysScoreTop Affiliating Genes
19.8IL10, TNF
29.8IL10, TNF
39.7CD4, CD8A
4
Show member pathways
9.3IL10, IL4, TNF
59.3CD4, IL10, IL4
6
Show member pathways
9.3CD4, CD8A, IL4
7
Show member pathways
9.2CD4, IL4, TLR3
89.1IL10, IL4, LTA
99.1IL10, IL4, LTA
109.0CD4, CD8A, IL10, TNF
11
Show member pathways
9.0CD4, IL10, IL4, TNF
129.0CD4, IL10, IL4, TNF
138.9CD4, CD8A, IL4, TNF
148.8IL10, IL4, LTA, TNF
158.8IL10, IL4, LTA, TNF
16
Show member pathways
8.8IL10, IL4, LTA, TNF
17
Show member pathways
8.7IL4, LTA, TLR3, TNF
188.6CD4, CD8A, IL10, IL4, TNF
19
Show member pathways
8.6CD4, CD8A, IL10, IL4, TNF
20
Show member pathways
8.5CD4, IL10, IL4, LTA, TNF
21
Show member pathways
8.4CD4, IL10, LTA, TLR3, TNF
228.0CD4, CD8A, IL10, IL4, TLR3, TNF
238.0CD4, CD8A, IL10, IL4, LTA, TNF
24
Show member pathways
8.0CD4, CD8A, IL10, IL4, LTA, TNF
25
Show member pathways
7.9CD4, IL10, IL4, LTA, TLR3, TNF

GO Terms for genes affiliated with Mucocutaneous Leishmaniasis

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Cellular components related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor complexGO:004210110.2CD4, CD8A
2cell surfaceGO:00099868.9CD4, CD8A, TLR3, TNF
3external side of plasma membraneGO:00098978.8CD4, CD8A, IL4, TNF

Biological processes related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

(show all 26)
idNameGO IDScoreTop Affiliating Genes
1receptor biosynthetic processGO:003280010.4IL10, TNF
2negative regulation of cytokine secretion involved in immune responseGO:000274010.4IL10, TNF
3positive regulation of mononuclear cell migrationGO:007167710.3IL4, TNF
4regulation of isotype switchingGO:004519110.3IL10, IL4
5positive regulation of cytokine secretionGO:005071510.3IL10, TNF
6positive regulation of calcium-mediated signalingGO:005085010.3CD4, CD8A
7necroptotic signaling pathwayGO:009752710.3TLR3, TNF
8negative regulation of interleukin-6 productionGO:003271510.3IL10, TNF
9positive regulation of chemokine productionGO:003272210.3TLR3, TNF
10positive regulation of chronic inflammatory response to antigenic stimulusGO:000287610.3LTA, TNF
11positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292510.2LTA, TNF
12type 2 immune responseGO:004209210.2IL10, IL4
13negative regulation of endothelial cell apoptotic processGO:200035210.2IL10, IL4
14negative regulation of nitric oxide biosynthetic processGO:004501910.2IL10, IL4
15positive regulation of NF-kappaB import into nucleusGO:004234610.2TLR3, TNF
16positive regulation of MHC class II biosynthetic processGO:004534810.2IL10, IL4
17defense response to protozoanGO:004283210.2IL10, IL4
18microglial cell activationGO:000177410.0IL4, TLR3
19negative regulation of osteoclast differentiationGO:004567110.0IL4, TLR3
20positive regulation of chemokine biosynthetic processGO:00450809.8IL4, TLR3, TNF
21negative regulation of growth of symbiont in hostGO:00441309.7IL10, LTA, TNF
22positive regulation of protein phosphorylationGO:00019349.7IL4, TLR3, TNF
23positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.5IL10, IL4, TNF
24positive regulation of interleukin-8 productionGO:00327579.3TLR3, TNF
25defense response to bacteriumGO:00427429.3IL10, TLR3, TNF
26immune responseGO:00069558.9CD4, CD8A, IL10, IL4

Molecular functions related to Mucocutaneous Leishmaniasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:000516410.0LTA, TNF
2coreceptor activityGO:00150269.7CD4, CD8A
3cytokine activityGO:00051258.7IL10, IL4, LTA, TNF

Sources for Mucocutaneous Leishmaniasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet