MCID: MCP008
MIFTS: 19

Mucoepidermoid Esophageal Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Mucoepidermoid Esophageal Carcinoma

MalaCards integrated aliases for Mucoepidermoid Esophageal Carcinoma:

Name: Mucoepidermoid Esophageal Carcinoma 12 14
Mucoepidermoid Carcinoma of the Esophagus 12
Esophageal Mucoepidermoid Carcinoma 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4686
NCIt 46 C5343
UMLS 69 C1333461

Summaries for Mucoepidermoid Esophageal Carcinoma

MalaCards based summary : Mucoepidermoid Esophageal Carcinoma, also known as mucoepidermoid carcinoma of the esophagus, is related to mucoepidermoid carcinoma and esophageal adenosquamous carcinoma. An important gene associated with Mucoepidermoid Esophageal Carcinoma is WWOX (WW Domain Containing Oxidoreductase), and among its related pathways/superpathways is DNA Damage. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Mucoepidermoid Esophageal Carcinoma

Diseases related to Mucoepidermoid Esophageal Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 mucoepidermoid carcinoma 10.2
2 esophageal adenosquamous carcinoma 10.0 CEACAM5 WWOX
3 mucositis 9.9
4 adenocarcinoma 9.9
5 intracranial chondrosarcoma 9.9 CEACAM5 TP53
6 malignant spiradenoma 9.9 CEACAM5 TP53
7 atypical follicular adenoma 9.9 CEACAM5 TP53
8 biliary papillomatosis 9.9 CEACAM5 TP53
9 ovary adenocarcinoma 9.9 CEACAM5 TP53
10 breast metaplastic carcinoma 9.9 CEACAM5 TP53
11 xanthogranulomatous cholecystitis 9.8 CEACAM5 TP53
12 gastrointestinal carcinoma 9.8 CEACAM5 TP53
13 bile duct adenocarcinoma 9.8 CEACAM5 TP53
14 gastrointestinal system benign neoplasm 9.8 CEACAM5 TP53
15 intestinal benign neoplasm 9.8 CEACAM5 TP53
16 malignant ovarian surface epithelial-stromal neoplasm 9.8 CEACAM5 TP53
17 lymph node cancer 9.8 TP53 WWOX
18 ovary epithelial cancer 9.8 CEACAM5 TP53
19 cystadenocarcinoma 9.8 CEACAM5 TP53
20 esophagus adenocarcinoma 9.8 TP53 WWOX
21 organ system benign neoplasm 9.8 CEACAM5 TP53
22 esophageal basaloid squamous cell carcinoma 9.8 TP53 WWOX
23 squamous cell papilloma 9.8 TP53 WWOX
24 integumentary system cancer 9.8 CEACAM5 TP53
25 gastric cardia adenocarcinoma 9.8 TP53 WWOX
26 cell type benign neoplasm 9.8 CEACAM5 TP53
27 esophageal disease 9.8 TP53 WWOX
28 pancreas adenocarcinoma 9.8 CEACAM5 TP53
29 colorectal adenocarcinoma 9.7 CEACAM5 TP53
30 ovarian cancer 1 9.7 CEACAM5 TP53
31 female reproductive organ cancer 9.7 CEACAM5 TP53
32 rectal neoplasm 9.7 CEACAM5 TP53
33 endocrine gland cancer 9.7 CEACAM5 TP53
34 gallbladder cancer 9.6 CEACAM5 TP53
35 small cell cancer of the lung 9.6 CEACAM5 TP53
36 vaccinia 9.5 CEACAM5 TP53
37 gastrointestinal system cancer 9.4 CEACAM5 TP53 WWOX
38 cell type cancer 9.4 CEACAM5 TP53 WWOX
39 squamous cell carcinoma 9.4 CEACAM5 TP53 WWOX
40 esophageal cancer 9.4 CEACAM5 TP53 WWOX
41 lung cancer susceptibility 3 9.4 CEACAM5 TP53

Graphical network of the top 20 diseases related to Mucoepidermoid Esophageal Carcinoma:



Diseases related to Mucoepidermoid Esophageal Carcinoma

Symptoms & Phenotypes for Mucoepidermoid Esophageal Carcinoma

GenomeRNAi Phenotypes related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

25 (show all 15)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.53 WWOX
2 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.53 WWOX
3 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.53 TP53
4 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.53 TP53
5 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.53 WWOX
6 Increased shRNA abundance (Z-score > 2) GR00366-A-129 9.53 WWOX
7 Increased shRNA abundance (Z-score > 2) GR00366-A-132 9.53 TP53
8 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.53 WWOX
9 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.53 TP53 WWOX
10 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.53 TP53 WWOX
11 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.53 TP53
12 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.53 TP53
13 Increased shRNA abundance (Z-score > 2) GR00366-A-39 9.53 TP53
14 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.53 WWOX
15 Decreased viability with paclitaxel GR00293-A 8.96 TP53 WWOX

Drugs & Therapeutics for Mucoepidermoid Esophageal Carcinoma

Search Clinical Trials , NIH Clinical Center for Mucoepidermoid Esophageal Carcinoma

Genetic Tests for Mucoepidermoid Esophageal Carcinoma

Anatomical Context for Mucoepidermoid Esophageal Carcinoma

Publications for Mucoepidermoid Esophageal Carcinoma

Articles related to Mucoepidermoid Esophageal Carcinoma:

# Title Authors Year
1
Primary mucoepidermoid carcinoma of the esophagus. ( 21587086 )
2011
2
Mucoepidermoid carcinoma of the esophagus treated by endoscopic mucosal resection. ( 14641323 )
2003
3
Biological behavior of mucoepidermoid carcinoma of the esophagus. ( 14578940 )
2003
4
Primary mucoepidermoid carcinoma of the esophagus misclassified as adenocarcinoma on endoscopic biopsy. ( 11051397 )
2000

Variations for Mucoepidermoid Esophageal Carcinoma

Expression for Mucoepidermoid Esophageal Carcinoma

Search GEO for disease gene expression data for Mucoepidermoid Esophageal Carcinoma.

Pathways for Mucoepidermoid Esophageal Carcinoma

Pathways related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.09 TP53 WWOX

GO Terms for Mucoepidermoid Esophageal Carcinoma

Biological processes related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 8.62 TP53 WWOX

Sources for Mucoepidermoid Esophageal Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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