MCID: MLT016
MIFTS: 48

Multicentric Reticulohistiocytosis malady

Categories: Rare diseases, Bone diseases, Skin diseases

Aliases & Classifications for Multicentric Reticulohistiocytosis

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Aliases & Descriptions for Multicentric Reticulohistiocytosis:

Name: Multicentric Reticulohistiocytosis 10 45 12 51
Lipoid Dermatoarthritis 10 51 65
 
Giant Cell Histiocytomatosis 51

Characteristics:

Orphanet epidemiological data:

51
multicentric reticulohistiocytosis:
Inheritance: Not applicable; Age of onset: Adult; Age of death: any age

Classifications:



External Ids:

Disease Ontology10 DOID:11824
ICD1027 E78.81, M14.3
NCIt42 C27896
SNOMED-CT59 190801003, 84241008
Orphanet51 139436
ICD10 via Orphanet28 D76.3
UMLS65 C0311284

Summaries for Multicentric Reticulohistiocytosis

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NIH Rare Diseases:45 Multicentric reticulohistiocytosis is a disease that is characterized by the presence of papules and nodules and associated with arthritis mutilans. the disease can involve the skin, the bones, the tendons, the muscles, the joints, and nearly any other organ (e.g., eyes, larynx, thyroid, salivary glands, bone marrow, heart, lung, kidney, liver, gastrointestinal tract). in the majority of cases, the cause of multicentric reticulohistiocytosis is unknown; however, it has been associated with an underlying cancer in about one fourth of cases, suggesting that it may be a paraneoplastic syndrome. last updated: 9/28/2012

MalaCards based summary: Multicentric Reticulohistiocytosis, also known as lipoid dermatoarthritis, is related to rheumatoid arthritis and arthritis, and has symptoms including abnormality of the oral cavity, abnormality of the skin and arthritis. An important gene associated with Multicentric Reticulohistiocytosis is TNFSF11 (Tumor Necrosis Factor Superfamily Member 11), and among its related pathways are Osteoclast Signaling and Osteoblast Signaling. Affiliated tissues include skin, bone and heart.

Disease Ontology:10 A syndrome that is characterized by papulonodular skin lesions containing a proliferation of true macrophages associated with arthritis.

Wikipedia:68 Multicentric reticulohistiocytosis is a multisystem disease beginning usually around the age of 50... more...

Related Diseases for Multicentric Reticulohistiocytosis

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Diseases related to Multicentric Reticulohistiocytosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 67)
idRelated DiseaseScoreTop Affiliating Genes
1rheumatoid arthritis29.1TNFRSF11B, TNFRSF1B, TNFSF11
2arthritis10.4
3hemorrhagic fever10.4TNFRSF11B, TNFSF11
4paget disease of bone 2, early-onset10.4TNFRSF11B, TNFSF11
5tibial hemimelia10.4TNFRSF11B, TNFSF11
6polycystic bone disease10.3TNFRSF11B, TNFSF11
7intrahepatic biliary papillomatosis10.3TNFRSF11B, TNFSF11
8mucocele of appendix10.3TNFRSF11B, TNFSF11
9collagenopathy, types ii and xi10.3TNFRSF11B, TNFSF11
10acrodermatitis chronica atrophicans10.3TNFRSF11B, TNFSF11
11marcus gunn phenomenon10.3TNFRSF11B, TNFSF11
12bone structure disease10.3TNFRSF11B, TNFSF11
13foster-kennedy syndrome10.3TNFRSF11B, TNFSF11
14van buchem disease, type 210.3TNFRSF11B, TNFSF11
15chromosomal disease10.3TNFRSF11B, TNFSF11
16bone development disease10.2TNFRSF11B, TNFSF11
17ceroid lipofuscinosis, neuronal, 610.2TNFRSF11B, TNFSF11
18eosinophilic gastritis10.2TNFRSF11B, TNFSF11
19dermatomyositis10.2
20myeloid leukemia10.2TNFRSF11B, TNFSF11
21mononeuritis of upper limb10.2TNFRSF11B, TNFSF11
22pulmonary neuroendocrine tumor10.1TNFRSF11B, TNFSF11
23central nervous system chondroma10.1TNFRSF11B, TNFSF11
24small cell cancer of the lung, somatic10.0TNFRSF11B, TNFSF11
25leprosy10.0
26granuloma annulare10.0
27lymphoma10.0
28lepromatous leprosy10.0
29melanoma10.0
30accessory nerve disease9.9TNFRSF11B, TNFSF11
31chromosome 9p deletion syndrome9.9PTPRC, TNFRSF1B
32cpt deficiency, hepatic, type ia9.8PTPRC, TNFRSF11B, TNFSF11
33systemic lupus erythematosus9.8
34psoriatic arthritis9.8
35burkitt lymphoma9.8
36nasopharyngeal carcinoma9.8
37myelofibrosis9.8
38osteoarthritis9.8
39primary biliary cirrhosis9.8
40pulmonary fibrosis9.8
41nasopharyngitis9.8
42pericardial effusion9.8
43gout9.8
44ovarian cancer9.8
45dermatitis9.8
46adenocarcinoma9.8
47xanthomatosis9.8
48arthropathy9.8
49tuberculosis9.8
50myopathy9.8

Graphical network of the top 20 diseases related to Multicentric Reticulohistiocytosis:



Diseases related to multicentric reticulohistiocytosis

Symptoms for Multicentric Reticulohistiocytosis

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Symptoms:

 51
  • follicular/erythematous/edematous papules/milium
  • enanthema/aphtosa/aphta/leukoplakia
  • arthritis/synovitis/synovial proliferation
  • muscle weakness/flaccidity
  • wasted (excluding lipodystrophy)/poorly muscled build/cachexy
  • fever/chilling

HPO human phenotypes related to Multicentric Reticulohistiocytosis:

(show all 6)
id Description Frequency HPO Source Accession
1 abnormality of the oral cavity hallmark (90%) HP:0000163
2 abnormality of the skin hallmark (90%) HP:0000951
3 arthritis hallmark (90%) HP:0001369
4 muscle weakness occasional (7.5%) HP:0001324
5 decreased body weight occasional (7.5%) HP:0004325
6 abnormality of temperature regulation occasional (7.5%) HP:0004370

UMLS symptoms related to Multicentric Reticulohistiocytosis:


vestibulitis, skin symptom, abnormal granulation tissue, osler's node, umbilical discharge

Drugs & Therapeutics for Multicentric Reticulohistiocytosis

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Drugs for Multicentric Reticulohistiocytosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
leucovorinapprovedPhase 39521492-18-854575
Synonyms:
(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
(6S)-Folinic acid
(6S)-Leucovorin
(S)-Leucovorin
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinic acid
Folinic acid calcium salt
Folinic acid calcium salt USP27
Folinic acid-SF
Fusilev
 
L-Folinic acid
L-leucovorin
Leucal
Leucovorin
Leucovorin Calcium
Leucovorin calcium
Leucovorin folinic acid
Leucovorin sodium
Leukovorin
Levofolene
Levofolinic acid
Levoleucovorin
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
Wellcovorin
2
PrednisoneapprovedPhase 3126753-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
Juvason
 
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Perrigo Prednisone
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rayos
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
3
MethotrexateapprovedPhase 314441959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
Methopterin
Methotextrate
 
Methotrate
Methotrexat
Methotrexate
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metoject
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Otrexup
Rasuvo
Rheumatrex
Rheumatrex Dose Pack
Trexall
4
VinblastineapprovedPhase 3230865-21-413342, 241903
Synonyms:
(2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE
(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine
(2xi,3beta,4'beta,19xi)-vincaleukoblastine
(3aR-(3aalpha,4beta,5beta,5abeta,9(3R*,5S*,7R*,9S*),10bR*,13aalpha))-methyl 4-(acetyloxy)-3a-ethyl-9-(5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino(5,4-b)indol-9-yl)-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino(8,1-cd)carbazole-5-carboxylate
143-67-9
1z2b
29060-LE
865-21-4
AC-20335
AC1L21JC
AC1L68D2
AC1MXZJ2
BIDD:PXR0201
BRD-K01188359-065-02-5
BSPBio_001228
BSPBio_003594
Bio-0111
C07201
C46H58N4O9
CCRIS 9002
CHEBI:171516
CHEBI:27375
CHEMBL159
CHEMBL607706
CID13342
CID241903
CID3823887
CID6710780
D08675
DB00570
EINECS 212-734-0
HMS2090K05
HSDB 3263
KBio3_003033
LS-1859
LS-187263
 
MolPort-002-518-262
MolPort-005-910-359
NCGC00022585-04
NCGC00181127-01
NCI-C04842
NCI60_004200
NChemBio.2007.10-comp22
NDC 0002-1452-01
NSC 47842
Neuro_000020
Nincaluicolflastine
Rozevin
SPBio_000680
STOCK1N-38480
Spectrum2_000890
Spectrum3_001994
UNII-5V9KLZ54CY
VLB
VR-8
Velban
Velbe
Vinblastin
Vinblastina
Vinblastina (TN)
Vinblastina [DCIT]
Vinblastina [Dcit]
Vinblastine
Vinblastine (INN)
Vinblastine Sulfate
Vinblastine [INN:BAN]
Vinblastinum
Vinblastinum [INN-Latin]
Vincaleucoblastin
Vincaleucoblastine
Vincaleukoblastine
Vincoblastine
nchembio873-comp22
vinblastine
5
Folic Acidapproved, nutraceuticalPhase 3292459-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
6Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 39988
7HormonesPhase 311748
8Immunologic FactorsPhase 318483
9Vitamin B ComplexPhase 32847
10Nucleic Acid Synthesis InhibitorsPhase 33836
11Hormone AntagonistsPhase 310002
12Tubulin ModulatorsPhase 34279
13Immunosuppressive AgentsPhase 310422
14glucocorticoidsPhase 33896
15Antimitotic AgentsPhase 34296
16Antineoplastic Agents, HormonalPhase 34256
17Antimetabolites, AntineoplasticPhase 35770
18AntimetabolitesPhase 39454
19Anti-Inflammatory AgentsPhase 38478
206-MercaptopurinePhase 3185
21Antineoplastic Agents, PhytogenicPhase 34294
22Folic Acid AntagonistsPhase 31643
23Antirheumatic AgentsPhase 38496
24Dermatologic AgentsPhase 34555
25Vitamin B9NutraceuticalPhase 32924
26FolateNutraceuticalPhase 32924
27Folinic AcidNutraceuticalPhase 32604

Interventional clinical trials:

idNameStatusNCT IDPhase
1H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell HistiocytosisCompletedNCT00488605Phase 3
2Prospective Evaluation of Adult Pulmonary Langerhans Cell HistiocytosisCompletedNCT01225601
3International Rare Histiocytic Disorders Registry (IRHDR)RecruitingNCT02285582

Search NIH Clinical Center for Multicentric Reticulohistiocytosis

Genetic Tests for Multicentric Reticulohistiocytosis

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Anatomical Context for Multicentric Reticulohistiocytosis

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MalaCards organs/tissues related to Multicentric Reticulohistiocytosis:

33
Skin, Bone, Heart, Liver, Lung, Kidney, Thyroid

Animal Models for Multicentric Reticulohistiocytosis or affiliated genes

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Publications for Multicentric Reticulohistiocytosis

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Articles related to Multicentric Reticulohistiocytosis:

(show top 50)    (show all 235)
idTitleAuthorsYear
1
Tumor necrosis factor antagonists in the treatment of multicentric reticulohistiocytosis: Current clinical evidence. (27175854)
2016
2
The usefulness of the scan with 67Ga-citrate in the multicentric reticulohistiocytosis. (23219024)
2013
3
Multicentric reticulohistiocytosis presenting with papulonodular skin lesions and arthritis mutilans. (23555066)
2013
4
Multicentric reticulohistiocytosis associated with liver carcinoma: report of a case. (22949898)
2012
5
Multicentric reticulohistiocytosis with elevated cytokine serum levels. (21658110)
2011
6
Multicentric reticulohistiocytosis. (23130232)
2011
7
A case of multicentric reticulohistiocytosis responsive to azathioprine in a patient with no underlying malignancy. (22070706)
2011
8
Paraneoplastic multicentric reticulohistiocytosis: a clinicopathologic challenge. (21508571)
2011
9
Multicentric reticulohistiocytosis successfully treated with infliximab: an illustrative case and evaluation of cytokine expression supporting anti-tumor necrosis factor therapy. (18936400)
2008
10
Multiple pink papules in the setting of arthritis and fever. Multicentric reticulohistiocytosis (MRH). (18936405)
2008
11
Multicentric reticulohistiocytosis: a systemic osteoclastic disease? (18311766)
2008
12
Multicentric reticulohistiocytosis associated with Burkitt lymphoma and adenocarcinoma. (18792542)
2008
13
Multicentric reticulohistiocytosis-mimicking dermatomyositis. Case report and review of the literature. (17377390)
2007
14
Multicentric reticulohistiocytosis with positive anticyclic citrullinated antibodies. (17595939)
2007
15
A case of multicentric reticulohistiocytosis with multiple lytic skull lesions. (16045682)
2005
16
Alleviation of polyarticular syndrome in multicentric reticulohistiocytosis with intravenous zoledronate. (16162909)
2005
17
Refractory multicentric reticulohistiocytosis treated by infliximab: two cases. (15789895)
2005
18
Multicentric reticulohistiocytosis with generalized systemic involvement. (15245533)
2004
19
Multicentric reticulohistiocytosis misdiagnosed as lepromatous leprosy. (15267195)
2003
20
Multicentric reticulohistiocytosis treated successfully with an anti-tumor necrosis factor agent: comment on the article by Gorman et al. (12632456)
2003
21
Multicentric reticulohistiocytosis: a rare cause of erosive arthropathy of the distal interphalangeal finger joints. (12006317)
2002
22
Multicentric reticulohistiocytosis in a 14-year-old girl. (12437557)
2002
23
Multicentric reticulohistiocytosis associated with SjAPgren's syndrome. (10971349)
2000
24
Multicentric reticulohistiocytosis in a child: radiologic findings and clinical correlation. (9879265)
1998
25
Atypical multicentric reticulohistiocytosis. (20921740)
1998
26
A case of multicentric reticulohistiocytosis, systemic sclerosis and SjAPgren syndrome. (9301147)
1997
27
Severe multicentric reticulohistiocytosis: disease stabilization achieved with methotrexate and hydroxychloroquine. (9375893)
1997
28
Upper airway involvement in multicentric reticulohistiocytosis. (8643284)
1996
29
Multicentric reticulohistiocytosis. (8929779)
1996
30
Unusual immunocytochemical and ultrastructural features of synovial fluid cells in multicentric reticulohistiocytosis. A case report. (8042427)
1994
31
Unusual digital nodules. Multicentric reticulohistiocytosis (MRH). (1599279)
1992
32
Close temporal and anatomic relationship between multicentric reticulohistiocytosis and carcinoma of the breast. (1629839)
1992
33
Methotrexate treatment of multicentric reticulohistiocytosis. (2066959)
1991
34
A case of multicentric reticulohistiocytosis: uncommon clinical signs and a report of T-cell marker characteristics. (3491619)
1986
35
A case of multicentric reticulohistiocytosis with thyroid involvement. (3771858)
1986
36
A mesothelioma presenting with multicentric reticulohistiocytosis. (3991408)
1985
37
Multicentric reticulohistiocytosis and SjAPgren's syndrome. (4093930)
1985
38
Topical nitrogen mustard therapy in multicentric reticulohistiocytosis. (7061747)
1982
39
Collagen phagocytosis in multicentric reticulohistiocytosis. (7229425)
1981
40
Multicentric reticulohistiocytosis with carcinoma-in-situ of the cervix. (465344)
1979
41
Multicentric reticulohistiocytosis and malignant disease. (204325)
1978
42
Relationship between multicentric reticulohistiocytosis and tuberculosis. (404438)
1977
43
Cardiopulmonary complications in multicentric reticulohistiocytosis. Report of a case. (133639)
1976
44
Multicentric reticulohistiocytosis with ovarian carcinoma. (1273092)
1976
45
Multicentric reticulohistiocytosis (lipoid dermatoarthritis). A multisystem disorder. (5030179)
1972
46
Multicentric reticulohistiocytosis. (5797976)
1969
47
Multicentric reticulohistiocytosis. Report of a case with histochemical studies. (4296608)
1968
48
Myositis and myotonia in a case of multicentric reticulohistiocytosis. (5635595)
1968
49
The nails in multicentric reticulohistiocytosis. (Lipoid dermato-arthritis). (6018996)
1967
50
A STUDY OF MULTICENTRIC RETICULOHISTIOCYTOSIS. (14122094)
1964

Variations for Multicentric Reticulohistiocytosis

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Expression for genes affiliated with Multicentric Reticulohistiocytosis

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Search GEO for disease gene expression data for Multicentric Reticulohistiocytosis.

Pathways for genes affiliated with Multicentric Reticulohistiocytosis

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GO Terms for genes affiliated with Multicentric Reticulohistiocytosis

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Biological processes related to Multicentric Reticulohistiocytosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of MAPK cascadeGO:00434109.5TNFRSF11B, TNFRSF1B
2apoptotic signaling pathwayGO:00971909.5TNFRSF11B, TNFRSF1B
3regulation of cell proliferationGO:00421279.2TNFRSF11B, TNFRSF1B
4dephosphorylationGO:00163119.1EPHX2, PTPRC
5response to lipopolysaccharideGO:00324969.1TNFRSF11B, TNFRSF1B
6inflammatory responseGO:00069548.8EPHX2, TNFRSF11B, TNFRSF1B

Sources for Multicentric Reticulohistiocytosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet