MCID: MLT016
MIFTS: 46

Multicentric Reticulohistiocytosis malady

Categories: Rare diseases, Bone diseases, Skin diseases

Aliases & Classifications for Multicentric Reticulohistiocytosis

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Summaries for Multicentric Reticulohistiocytosis

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NIH Rare Diseases:48 Multicentric reticulohistiocytosis is a disease that is characterized by the presence of papules and nodules and associated with arthritis mutilans. the disease can involve the skin, the bones, the tendons, the muscles, the joints, and nearly any other organ (e.g., eyes, larynx, thyroid, salivary glands, bone marrow, heart, lung, kidney, liver, gastrointestinal tract). in the majority of cases, the cause of multicentric reticulohistiocytosis is unknown; however, it has been associated with an underlying cancer in about one fourth of cases, suggesting that it may be a paraneoplastic syndrome. last updated: 9/28/2012

MalaCards based summary: Multicentric Reticulohistiocytosis, also known as lipoid dermatoarthritis, is related to rheumatoid arthritis and arthritis, and has symptoms including Array, Array and Array. An important gene associated with Multicentric Reticulohistiocytosis is TNFSF11 (TNF Superfamily Member 11), and among its related pathways are Transcription_Role of VDR in regulation of genes involved in osteoporosis and TNF Superfamily Pathway: Human Ligand-Receptor Interactions and their Associated Functions. Affiliated tissues include skin, bone and liver, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and immune system.

Disease Ontology:11 A syndrome that is characterized by papulonodular skin lesions containing a proliferation of true macrophages associated with arthritis.

Wikipedia:71 Multicentric reticulohistiocytosis is a multisystem disease beginning usually around the age of 50... more...

Related Diseases for Multicentric Reticulohistiocytosis

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Diseases related to Multicentric Reticulohistiocytosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 98)
idRelated DiseaseScoreTop Affiliating Genes
1rheumatoid arthritis29.5CSF1, TNFRSF11B, TNFSF11
2arthritis10.3
3congenital myasthenic syndrome10.2F13A1, VIM
4postgerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma10.2F13A1, VIM
5hematologic cancer10.2F13A1, VIM
6cavernous sinus meningioma10.2F13A1, VIM
7dyslexia10.2F13A1, VIM
8hinman syndrome10.2PTPRC, VIM
9diarrhea, chronic, with villous atrophy10.2F13A1, VIM
10ribbing disease10.2PTPRC, VIM
11appendix mucinous cystadenocarcinoma10.2PTPRC, VIM
12caroli disease10.2F13A1, VIM
13omodysplasia 210.2PTPRC, VIM
14congenital muscular dystrophy with hyperlaxity10.2PTPRC, VIM
15juvenile xanthogranuloma10.2F13A1, VIM
16lung benign neoplasm10.1PTPRC, VIM
17desmoid tumor10.1PTPRC, VIM
18neutrophil immunodeficiency syndrome10.1F13A1, VIM
19kidney benign neoplasm10.1PTPRC, VIM
20diabetes persistent mullerian ducts10.1PTPRC, VIM
21central nervous system hemangioma10.1TNFRSF11B, VIM
22phka2-related phosphorylase kinase deficiency10.1TNFRSF11B, TNFSF11
23birk-barel mental retardation dysmorphism syndrome10.1TNFRSF11B, TNFSF11
24osteopetrosis, autosomal recessive 710.1TNFRSF11B, TNFSF11
25hepatic fibrosis renal cysts mental retardation10.1TNFRSF11B, TNFSF11
26epilepsy, idiopathic generalized 1410.1TNFRSF11B, TNFSF11
27pulmonary immaturity10.1F13A1, PTPRC
28peripheral scars of retina10.1TNFRSF11B, TNFSF11
29polyomavirus allograft nephropathy10.1TNFRSF11B, TNFSF11
30microcephaly 10, primary, autosomal recessive10.1TNFRSF11B, TNFSF11
31maroteaux stanescu cousin syndrome10.1TNFRSF11B, TNFSF11
32bronchus cancer10.1TNFRSF11B, TNFSF11
33bulbomembranous urethral cancer10.1TNFRSF11B, TNFSF11
34dermatomyositis10.1
35acrorenal syndrome10.1TNFRSF11B, TNFSF11
36glossitis10.1TNFRSF11B, TNFSF11
37chromosomal disease10.1TNFRSF11B, TNFSF11
38post-traumatic stress disorder10.0TNFRSF11B, TNFSF11
39celiac disease10.0TNFRSF11B, TNFSF11
40dysbaric osteonecrosis10.0TNFRSF11B, TNFSF11
41dentin dysplasia with sclerotic bones10.0CSF1, F13A1
42ischemic bone disease10.0TNFRSF11B, TNFSF11
43plasma protein metabolism disease10.0CSF1, TNFSF11
44vascular dementia10.0TNFRSF11B, TNFSF11
45impotence10.0CSF1, TNFSF11
46intrahepatic cholestasis10.0TNFRSF11B, TNFSF11
47keratoconus10.0CSF1, TNFSF11
48developmental coordination disorder10.0PTPRC, TNFSF11, VIM
49ceroid lipofuscinosis, neuronal, kufs type, adult onset10.0TNFRSF11B, TNFSF11
50fungal gastritis9.9TNFRSF11B, TNFSF11

Graphical network of the top 20 diseases related to Multicentric Reticulohistiocytosis:



Diseases related to multicentric reticulohistiocytosis

Symptoms & Phenotypes for Multicentric Reticulohistiocytosis

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Human phenotypes related to Multicentric Reticulohistiocytosis:

 54 64 (show all 6)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 muscle weakness64 54 Occasional (29-5%) HP:0001324
2 arthritis64 54 Very frequent (99-80%) HP:0001369
3 fever64 54 Occasional (29-5%) HP:0001945
4 cachexia64 54 Occasional (29-5%) HP:0004326
5 histiocytosis64 54 Very frequent (99-80%) HP:0100727
6 skin nodule64 54 Very frequent (99-80%) HP:0200036

GenomeRNAi Phenotypes related to Multicentric Reticulohistiocytosis according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-849.6CSF1, TNFSF11, VIM

MGI Mouse Phenotypes related to Multicentric Reticulohistiocytosis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.4CSF1, PTPRC, TNFRSF11B, TNFSF11, VIM
2MP:00053977.9CSF1, F13A1, PTPRC, TNFRSF11B, TNFSF11, VIM
3MP:00107687.8CSF1, F13A1, PTPRC, TNFRSF11B, TNFSF11, VIM
4MP:00053887.7CSF1, F13A1, PTPRC, TNFSF11, VIM

Drugs & Therapeutics for Multicentric Reticulohistiocytosis

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Drugs for Multicentric Reticulohistiocytosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Prednisoneapproved, vet_approvedPhase 3139853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
2
VinblastineapprovedPhase 3420865-21-413342, 241903
Synonyms:
(2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE
(2xi,3beta,4'beta,19xi)-vincaleukoblastine
(3aR-(3aalpha,4beta,5beta,5abeta,9(3R*,5S*,7R*,9S*),10bR*,13aalpha))-methyl 4-(acetyloxy)-3a-ethyl-9-(5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino(5,4-b)indol-9-yl)-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino(8,1-cd)carbazole-5-carboxylate
143-67-9
1z2b
29060-LE
865-21-4
AC-20335
AC1L21JC
AC1L68D2
AC1MXZJ2
BIDD:PXR0201
BRD-K01188359-065-02-5
BSPBio_001228
BSPBio_003594
Bio-0111
C07201
C46H58N4O9
CCRIS 9002
CHEBI:171516
CHEBI:27375
CHEMBL159
CHEMBL607706
CID13342
CID241903
CID3823887
CID6710780
D08675
DB00570
EINECS 212-734-0
HMS2090K05
HSDB 3263
KBio3_003033
LS-1859
LS-187263
MolPort-002-518-262
 
MolPort-005-910-359
NCGC00022585-04
NCGC00181127-01
NCI-C04842
NCI60_004200
NChemBio.2007.10-comp22
NDC 0002-1452-01
NSC 47842
Neuro_000020
Nincaluicolflastine
Rozevin
SPBio_000680
STOCK1N-38480
Spectrum2_000890
Spectrum3_001994
UNII-5V9KLZ54CY
VLB
VR-8
Velban
Velbe
Vinblastin
Vinblastina
Vinblastina (TN)
Vinblastina [DCIT]
Vinblastina [Dcit]
Vinblastine
Vinblastine (INN)
Vinblastine Sulfate
Vinblastine [INN:BAN]
Vinblastinum
Vinblastinum [INN-Latin]
Vincaleucoblastin
Vincaleucoblastine
Vincaleukoblastine
Vincoblastine
nchembio873-comp22
vinblastine
3
MethotrexateapprovedPhase 315511959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
4
leucovorinapproved, NutraceuticalPhase 3323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
5
Folic Acidapproved, nutraceutical, vet_approvedPhase 3439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
6HormonesPhase 314415
7Hormone AntagonistsPhase 313180
8Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 313168
9Immunosuppressive AgentsPhase 313086
10Nucleic Acid Synthesis InhibitorsPhase 34962
11glucocorticoidsPhase 35103
12Vitamin B ComplexPhase 34337
13Folic Acid AntagonistsPhase 32257
14Antimitotic AgentsPhase 35657
15Antimetabolites, AntineoplasticPhase 37361
16AntimetabolitesPhase 312054
17Anti-Inflammatory AgentsPhase 310729
186-MercaptopurinePhase 3202
19Antineoplastic Agents, HormonalPhase 35592
20Antineoplastic Agents, PhytogenicPhase 35602
21Dermatologic AgentsPhase 35806
22Antirheumatic AgentsPhase 310956
23Vitamin B9NutraceuticalPhase 34392
24FolateNutraceuticalPhase 34392

Interventional clinical trials:

idNameStatusNCT IDPhase
1H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell HistiocytosisCompletedNCT00488605Phase 3
2Prospective Evaluation of Adult Pulmonary Langerhans Cell HistiocytosisCompletedNCT01225601
3International Rare Histiocytic Disorders Registry (IRHDR)RecruitingNCT02285582

Search NIH Clinical Center for Multicentric Reticulohistiocytosis

Genetic Tests for Multicentric Reticulohistiocytosis

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Anatomical Context for Multicentric Reticulohistiocytosis

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MalaCards organs/tissues related to Multicentric Reticulohistiocytosis:

36
Skin, Bone, Liver, Thyroid, Salivary gland, Lung, Bone marrow

Publications for Multicentric Reticulohistiocytosis

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Articles related to Multicentric Reticulohistiocytosis:

(show top 50)    (show all 239)
idTitleAuthorsYear
1
Multicentric Reticulohistiocytosis: an Unknown Source of Embolic Stroke. (27839900)
2017
2
Multicentric Reticulohistiocytosis: A Unique Case of Chronic Colitis. (27580770)
2016
3
Metastatic Inflammatory Breast Cancer Associated With Multicentric Reticulohistiocytosis Successfully Treated With Zoledronic Acid. (27435627)
2016
4
Tumor necrosis factor antagonists in the treatment of multicentric reticulohistiocytosis: Current clinical evidence. (27175854)
2016
5
Efficacy of Vinblastine and Prednisone in Multicentric Reticulohistiocytosis With Onset in Infancy. (27199388)
2016
6
Successful treatment of FKBP51-expressed multicentric reticulohistiocytosis using combination therapy with low-dose denosumab and tacrolimus. (26652057)
2016
7
Nailfold Capillary Patterns in a Patient With Multicentric Reticulohistiocytosis and Raynaud Phenomenon. (27219314)
2016
8
Multicentric Reticulohistiocytosis in a 5-Year-Old Girl. (27492868)
2016
9
Multicentric reticulohistiocytosis: Rheumatology perspective. (27886798)
2016
10
Multicentric reticulohistiocytosis (MRH): case report with review of literature between 1991 and 2014 with in depth analysis of various treatment regimens and outcomes. (27026876)
2016
11
18F-FDG PET/CT Findings in Multicentric Reticulohistiocytosis. (26571445)
2015
12
Multicentric Reticulohistiocytosis: A Case Report of an Atypical Presentation in a 2-Year-Old. (25727569)
2015
13
Organizing pneumonia associated with multicentric reticulohistiocytosis. (26740877)
2015
14
Multicentric reticulohistiocytosis: a critical review. (25900189)
2015
15
Bilateral Total Hip Arthroplasty in a Rare Case of Multicentric Reticulohistiocytosis. (26640636)
2015
16
Erythema, papules, and arthralgia associated with liver cancer: report of a rare case of multicentric reticulohistiocytosis. (26045857)
2015
17
Successful Treatment of Multicentric Reticulohistiocytosis with Adalimumab, Prednisolone and Methotrexate. (26072967)
2015
18
Multicentric reticulohistiocytosis can mimic rheumatoid arthritis. (24692603)
2014
19
A case of multicentric reticulohistiocytosis. (25211404)
2014
20
Multicentric reticulohistiocytosis: case report with response to infliximab and review of treatment options. (24733253)
2014
21
Multicentric reticulohistiocytosis. (25092372)
2014
22
Multicentric reticulohistiocytosis: contrasting presentations in 2 Hispanic patients. (24897136)
2014
23
Multicentric reticulohistiocytosis misdiagnosed as rheumatoid arthritis. (25040783)
2014
24
Granuloma annulare mimicking multicentric reticulohistiocytosis. (24314776)
2013
25
Hand surgery for Multicentric Reticulohistiocytosis: A new avenue of treatment and review of the literature. (23796955)
2013
26
Multicentric reticulohistiocytosis presenting with papulonodular skin lesions and arthritis mutilans. (23555066)
2013
27
Treatment of multicentric reticulohistiocytosis with adalimumab, minocycline, methotrexate. (23441782)
2013
28
Treatment of multicentric reticulohistiocytosis with tocilizumab. (23872542)
2013
29
Multicentric reticulohistiocytosis: a rare yet challenging disease. (23417597)
2013
30
The usefulness of the scan with 67Ga-citrate in the multicentric reticulohistiocytosis. (23219024)
2013
31
Treatment of facial lesions of multicentric reticulohistiocytosis by carbon dioxide laser. (24163535)
2013
32
Multicentric reticulohistiocytosis with extra-mammillary Paget's disease: a case report. (24168966)
2013
33
Multicentric reticulohistiocytosis. (22945300)
2013
34
Leonine facies in the cutaneous form of multicentric reticulohistiocytosis. (22864143)
2012
35
Multicentric reticulohistiocytosis associated with liver carcinoma: report of a case. (22949898)
2012
36
Multicentric reticulohistiocytosis presenting with the cutaneous features of photosensitivity dermatitis. (21545508)
2012
37
Multicentric reticulohistiocytosis masquerading as dermatomyositis: similar and different features. (21950771)
2012
38
Multicentric reticulohistiocytosis and fibroblastic rheumatism. (23040366)
2012
39
Resident rounds. Part III: Multicentric reticulohistiocytosis presenting as granuloma annulare. (23547330)
2012
40
Multicentric reticulohistiocytosis: a unique case with pulmonary fibrosis. (22351825)
2012
41
Overexpression of monocyte chemoattractant protein-1 in the overlying epidermis of multicentric reticulohistiocytosis lesions: a case report. (22435444)
2012
42
Progressive multicentric reticulohistiocytosis. (22449693)
2012
43
Multicentric reticulohistiocytosis: a rare case report. (22837570)
2012
44
Multicentric reticulohistiocytosis with dermatomyositis-like features: a more common disease presentation than previously thought. (21252485)
2011
45
Multicentric reticulohistiocytosis. (23130232)
2011
46
Multicentric reticulohistiocytosis associated arthritis responding to anti-TNF and methotrexate. (21485770)
2011
47
Malignancy-associated multicentric reticulohistiocytosis. (20012625)
2011
48
Ultraviolet light-induced KAPbner phenomenon contributes to the development of skin eruptions in multicentric reticulohistiocytosis. (21279300)
2011
49
Multicentric reticulohistiocytosis with elevated cytokine serum levels. (21658110)
2011
50
A case of multicentric reticulohistiocytosis responsive to azathioprine in a patient with no underlying malignancy. (22070706)
2011

Variations for Multicentric Reticulohistiocytosis

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Expression for genes affiliated with Multicentric Reticulohistiocytosis

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Search GEO for disease gene expression data for Multicentric Reticulohistiocytosis.

Pathways for genes affiliated with Multicentric Reticulohistiocytosis

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GO Terms for genes affiliated with Multicentric Reticulohistiocytosis

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Biological processes related to Multicentric Reticulohistiocytosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1osteoclast differentiationGO:00303169.8CSF1, TNFSF11
2osteoclast proliferationGO:00021589.8CSF1, TNFSF11
3positive regulation of osteoclast differentiationGO:00456729.7CSF1, TNFSF11
4positive regulation of protein kinase activityGO:00458609.1CSF1, PTPRC

Molecular functions related to Multicentric Reticulohistiocytosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051258.6CSF1, TNFRSF11B, TNFSF11

Sources for Multicentric Reticulohistiocytosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet