Mumps disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

MUMPS MCID: MMP001 MIFTS: 59	Mumps (MUMPS) malady Infectious diseases category
6 symptoms, 61 genes, 11 tissues, 134 related diseases, clinical trials.

Summaries for Mumps

Sources:
⁸Disease Ontology, ³³MedlinePlus, ³CDC, ⁶³Wikipedia, ³²MalaCards
See all sources

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MedlinePlus:³³ Mumps is an illness caused by the mumps virus. it starts with fever headache muscle aches tiredness loss of appetite after that, the salivary glands under the ears or jaw become swollen and tender. the swelling can be on one or both sides of the face. symptoms last 7 to 10 days. serious complications are rare. you can catch mumps by being with another person who has it. there is no treatment for mumps, but the measles-mumps-rubella (mmr) vaccine can prevent it. before the routine vaccination program in the united states, mumps was a common illness in infants, children and young adults. now it is a rare disease in the u.s. centers for disease control and prevention

MalaCards: Mumps is related to measles and rubella, and has symptoms including swollen, loss of appetite and tiredness. An important gene associated with Mumps is STAT2 (signal transducer and activator of transcription 2, 113kDa), and among its related pathways are IL-22 Pathway and Tuberculosis. The compounds mumps and cycloheximide have been mentioned in the context of this disorder. Affiliated tissues include salivary gl, salivary gland and testes, and related mouse phenotypes are mortality/aging and hematopoietic system.

Disease Ontology:⁸ A viral infectious disease that results in inflammation located in salivary gland, has material basis in mumps virus, which is transmitted by droplet spread of saliva or mucus from the mouth, nose, or throat of an infected person, or transmitted by contaminated fomites. the infection has symptom fever, has symptom headache, has symptom muscle aches, has symptom tiredness, has symptom loss of appetite, has symptom swollen and tender salivary glands under the ears or jaw on one or both sides of the face.

CDC:³ Mumps is a contagious disease that is caused by the mumps virus. Mumps typically starts with a few days of fever, headache, muscle aches, tiredness, and loss of appetite, and is followed by swelling of salivary glands. Anyone who is not immune from either previous mumps infection or from vaccination can get mumps. Before the routine vaccination program was introduced in the United States, mumps was a common illness in infants, children and young adults. Because most people have now been vaccinated, mumps has become a rare disease in the United States...more

Wikipedia:⁶³ Mumps (epidemic parotitis) is a viral disease of the human species, caused by the mumps virus. Before... more...

Aliases & Classifications for Mumps

Sources:
⁸Disease Ontology, ⁴²NIH Rare Diseases, ¹⁰DISEASES, ⁴⁴Novoseek, ³³MedlinePlus, ⁶⁰UMLS, ⁵⁶SNOMED-CT, ³⁹NCIt, ²⁷ICD9CM, ³⁴MeSH, ²⁵ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases

ICD10: ²⁵

Certain infectious and parasitic diseases

Other viral diseases

Mumps

Mumps with other complications

Mumps without complication

Aliases & Descriptions:

mumps ⁸ ⁴² ¹⁰ ⁴⁴ ³³ ⁶⁰

External Ids:

Disease Ontology⁸ DOID:10264

NCIt³⁹ C29888

ICD9CM²⁷ 072

SNOMED-CT⁵⁶ 154352008, 186652008, 186651001 36989005, 240526004, more

MeSH³⁴ D009107

ICD10²⁵ B26, B26.8, B26.9

UMLS⁶⁰ C0026780

Related Diseases for Mumps

Sources:
¹⁷GeneCards, ¹⁸GeneDecks
See all sources

Diseases in the Mumps family:

Congenital Mumps

Diseases related to Mumps via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50) (show all 134)

id	Related Disease	Score	Top Affiliating Genes
1	measles	31.5	IRF1, STAT1, DPT
2	rubella	31.5	DPT
3	hepatitis	30.6	STAT1, IRF1, IFNA2
4	influenza	30.6	NEU1, IRF1, STAT1, ISG20, EIF2AK2
5	hepatitis b	30.4	EIF2AK2, STAT1, DPT, ISG20, IRF1, IFNA2
6	stomatitis	29.9	IFNA2
7	ovarian cancer	29.9	IRF1, NEU1
8	hepatitis c	29.9	IRF1, ISG20, EIF2AK2, IFNA2, STAT1
9	acute leukemia	29.9	IRF1, STAT1, EIF2AK2
10	herpes simplex	29.9	EIF2AK2, NEU1, IRF1, ISG20, STAT1
11	leukemia	29.9	IRF2, IFNA2, IRF1, ISG20, EIF2AK2, STAT1
12	asthma	29.9	IRF1, STAT1, NEU1
13	multiple sclerosis	29.7	EIF2AK2, IRF1, STAT1
14	orchitis	10.6
15	meningitis	10.6
16	aseptic meningitis	10.6
17	parotitis	10.5
18	meningoencephalitis	10.4
19	encephalitis	10.3
20	tetanus	10.3
21	endocardial fibroelastosis	10.3
22	epididymo-orchitis	10.3
23	diphtheria	10.2
24	hepatitis a	10.2
25	poliomyelitis	10.2
26	myelitis	10.2
27	pancreatitis	10.2
28	pertussis	10.2
29	hydrocephalus	10.2
30	purpura	10.2
31	sialadenitis	10.1
32	chickenpox	10.1
33	labyrinthitis	10.1
34	acute pancreatitis	10.1
35	infertility	10.1
36	arthritis	10.1
37	myocarditis	10.1
38	congenital mumps	10.1
39	multiple myeloma	10.0	BST2
40	sarcoma	10.0	STAT1
41	myeloid leukemia	10.0	NEU1, STAT2, IRF1, IRF9, STAT1
42	chronic myeloid leukemia	10.0	STAT1, ISG20, IRF2, EIF2AK2, IFNA2
43	myeloma	10.0	IFNA2, IRF1, STAT1, NEU1
44	hepatitis d	10.0	EIF2AK2, IFNA2
45	carcinoid syndrome	10.0	IFNA2, IRF2, IRF1
46	hepatocellular carcinoma	10.0	IFNA2, IRF1, NEU1, EIF2AK2
47	colon cancer	10.0	STAT2, STAT1, NEU1, IRF1
48	deficiency anemia	10.0	IFNA2
49	tuberculosis	10.0	MRC1, PDP1, IRF9, IRF1, STAT2, STAT1
50	ipex syndrome	10.0	ISG20, EIF2AK2, NEU1, IRF1, BST2, STAT1

Graphical network of the top 20 diseases related to Mumps:

Clinical Features for Mumps

Sources:
⁸Disease Ontology
See all sources

Symptoms:

⁸

swollen
loss of appetite
tiredness

muscle aches
headache
fever

Drugs & Therapeutics for Mumps

Sources:
⁵CenterWatch, ⁴¹NIH Clinical Center, ⁶ClinicalTrials, ⁶⁰UMLS, ⁴⁰NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Mumps

Drug clinical trials:

Search ClinicalTrials for Mumps

Search NIH Clinical Center for Mumps

Search CenterWatch for Mumps

Genetic Tests for Mumps

Anatomical Context for Mumps

Sources:
³²MalaCards, ¹⁴FMA
See all sources

MalaCards organs/tissues related to Mumps:

³²

Salivary gland, Testes, B cells, Endothelial, T cells, Skin, Thyroid, Brain, Bone, Bone marrow

FMA organs/tissues related to Mumps:

¹⁴

Salivary gl

Animal Models for Mumps or affiliated genes

Sources:
³⁶MGI
See all sources

MGI Mouse Phenotypes related to Mumps:

³⁶

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	mortality/aging	MP:0010768	9.9	IL10RB, DHX58, CHMP4B, NEU1, STAT1, STAT2
2	hematopoietic system phenotype	MP:0005397	9.8	EIF2AK2, IL10RB, NEU1, STAT1, STAT2, BST2
3	immune system phenotype	MP:0005387	9.8	EIF2AK2, DHX58, NEU1, STAT1, STAT2, BST2
4	cellular phenotype	MP:0005384	9.6	IRF1, EIF2AK2, IL10RB, DHX58, NEU1, STAT1

Publications for Mumps

Sources:
⁵⁰PubMed
See all sources

Articles related to Mumps:

(show top 50) (show all 658)

id	Title	Authors	Year
1	Increased levels of cytokines in cerebrospinal fluid of children with aseptic meningitis caused by mumps virus and echovirus 30. (24313836)	Sulik A.... Oldak E.	2014
2	Mumps among highly vaccinated people: Investigation of an outbreak in a French Military Parachuting Unit, 2013. (24035994)	Gobet A.... Michel R.	2014
3	Comparison of automated chemiluminescence immunoassays with capture enzyme immunoassays for the detection of measles and mumps IgM antibodies in serum. (24183918)	Haywood B.... Haque T.	2014
4	Influence of Vaccination dose and clinico-demographical factors on antibody titers against measles, rubella, mumps, and varicella-zoster viruses among university students in Japan. (24270137)	Takeuchi J.... Hiraide A.	2013
5	Outbreak-related mumps vaccine effectiveness among a cohort of children and of young adults in Germany 2011. (24091837)	Takla A.... Koch J.	2013
6	Characterisation of mumps virus genotype C among patients with mumps in India. (23883719)	Jeevan M.... Thangam M.	2013
7	Estimates of mumps seroprevalence may be influenced by antibody specificity and serologic method. (24371258)	Latner D.R.... Hickman C.J.	2013
8	Measles, mumps, and rubella vaccine: a new option to treat common warts? (23786798)	Iorizzo M.... Marazza G.	2013
9	A rare complication of coronary angiography: 'iodide mumps'. (23744842)	Sajeev C.G.... Muneer K.	2013
10	Hydrocephalus due to aqueductal stenosis in a case of mumps meningoencephalitis: A rare complication. (24082949)	Pongener I.... Dewan V.	2013
11	Complicated mumps viral infection: an unusual presentation affecting only submandibular gland. (23562490)	Myung N.S.... Koo S.K.	2013
12	A new method for the detection of neutralizing antibodies against mumps virus. (23861738)	Matsubara K.... Nakayama T.	2013
13	Seroprevalence of measles, mumps, rubella, varicella-zoster and hepatitis A-C in Emirati medical students. (23217121)	Sheek-Hussein M.... Souid A.K.	2012
14	Immunogenicity and safety of a two-dose regimen of a combined measles, mumps, rubella and varicella live vaccine (ProQuad(Ar)) in infants from 9 months of age. (22406278)	Vesikari T.... Baudin M.	2012
15	Attitudinal and demographic predictors of measles-mumps-rubella vaccine (MMR) uptake during the UK catch-up campaign 2008-09: cross-sectional survey. (21602931)	Brown K.... Sevdalis N.	2011
16	Immunogenicity and safety of an inactivated hepatitis A vaccine when coadministered with measles-mumps-rubella and varicella vaccines in children less than 2 years of age. (21617573)	Rinderknecht S.... Trofa A.F.	2011
17	Effect of weather variability on the incidence of mumps in children: a time-series analysis. (21211102)	Onozuka D.... Hashizume M.	2011
18	Safety and immunogenicity of coadministering a combined meningococcal serogroup C and Haemophilus influenzae type b conjugate vaccine with 7-valent pneumococcal conjugate vaccine and measles, mumps, and rubella vaccine at 12 months of age. (21191076)	Miller E.... Borrow R.	2011
19	Low measles, mumps and rubella (MMR) vaccine uptake in hospital healthcare worker contacts following suspected mumps infection. (20542592)	Williams C.J.... Nair P.	2010
20	Molecular epidemiological evaluation of the recent resurgence in mumps virus infections in Ireland. (20660212)	Carr M.J.... Hassan J.	2010
21	Ongoing mumps outbreak in a student population with high vaccination coverage, Netherlands, 2010. (20460086)	Whelan J.... HahnAc S.	2010
22	Mumps outbreak - New York, New Jersey, Quebec, 2009. (19940833)		2009
23	Presence of lysine at aa 335 of the hemagglutinin-neuraminidase protein of mumps virus vaccine strain Urabe AM9 is not a requirement for neurovirulence. (19660591)	Sauder C.J.... Rubin S.A.	2009
24	Does vaccination with the varicella vaccine within four weeks after the measles, mumps and rubella vaccine reduce protection? (20885799)	Lapphra K.... Scheifele D.	2009
25	Commentary: Is Japan deaf to mumps vaccination? (19209099)	Plotkin S.A.	2009
26	Comparative analysis of the complete nucleotide sequences of measles, mumps, and rubella strain genomes contained in Priorix-Tetra and ProQuad live attenuated combined vaccines. (19428841)	Tillieux S.L.... Vassilev V.	2009
27	Laboratory diagnosis of mumps in a partially immunized population: The Nova Scotia experience. (21119794)	Hatchette T.... Forward K.	2009
28	Mumps: a resurgent disease with protean manifestations. (18928441)	Senanayake S.N.	2008
29	An increase in the number of mumps cases in the Czech Republic, 2005-2006. (18768117)	Boxall N.... CA!stkovA! J.	2008
30	Recent resurgence of mumps in the United States. (18403766)	Dayan G.H.... Seward J.F.	2008
31	Antibody induced by immunization with the Jeryl Lynn mumps vaccine strain effectively neutralizes a heterologous wild-type mumps virus associated with a large outbreak. (18558869)	Rubin S.A.... Beeler J.	2008
32	Transmission of the L-Zagreb mumps vaccine virus, Croatia, 2005-2008. (18768116)	Kaic B.... Ilic A.	2008
33	Measles, mumps and rubella infections and atopic disorders in MMR-unvaccinated and MMR-vaccinated children. (18266826)	Bernsen R.M.... van der Wouden J.C.	2008
34	A new challenge for Europe: introducing a pediatric quadrivalent vaccine for measles, mumps, rubella, and varicella. (18162247)	Ramet J.	2007
35	Mumps and the media: changes in the reporting of mumps in response to newspaper coverage. (17435202)	Olowokure B.... Fleming A.	2007
36	Complementary findings in clinical and epidemiologic features of mumps and mumps meningoencephalitis in children without mumps vaccination. (15660864)	Kanra G.... Ceyhan M.	2004
37	Surveillance of measles-mumps-rubella vaccine-associated aseptic meningitis in Germany. (12478324)	SchlipkAPter U.... Weil J.	2002
38	Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism. (12145534)	Singh V.K.... Nelson C.	2002
39	Neuronal apoptosis mediated by IL-1 beta expression in viral encephalitis caused by a neuroadapted strain of the mumps virus (Kilham Strain) in hamsters. (11681839)	Takikita S.... Shimada M.	2001
40	Mumps interstitial nephritis: a case report. (10603152)	KabakuA9 N.... Yekeler H.	1999
41	Transverse myelitis following mumps in an adult -- a case report with MRI correlation. (9405004)	Venketasubramanian N.	1997
42	Successful interferon-alpha 2 a therapy for a patient with acute mumps orchitis. (7744163)	RA1ther U.... Jipp P.	1995
43	Experimental mumps labyrinthitis in monkeys (Macaca irus)--immunohistochemical and ultrastructural studies. (3061375)	Tanaka K.... Sugiura A.	1988
44	Mumps pancreatitis without parotitis. (4692679)	Naficy K.... Ghadimi H.	1973
45	Mumps arthritis without parotitis. (5123807)	Solem J.H.	1971
46	Mumps epididymo-orchitis and its treatment with cortisone. Report of a controlled trial. (13757310)	Kocen R.S.... CRITCHLEY E.	1961
47	Congenital defects in infants following mumps during pregnancy; a review of the literature and a report of chorioretinitis due to fetal infection. (13417036)	HOLOWACH J.... Becker B.	1957
48	Iritis and glaucoma associated with mumps. (13147625)	Riffenburgh R.S.	1954
49	Acute mesenteric vascular occlusion following mumps. (13096824)	ELKAN W.	1953
50	Acute myocarditis in mumps (epidemic parotitis). (21011878)	ROSENBERG D.H.	1945

Genes related to Mumps

Sources:
¹⁷GeneCards, ⁴⁵Novus Biologicals, ³¹LifeSpan BioSciences, Inc.
See all sources

Genes related to Mumps:

(show top 50) (show all 61)

id	Symbol	Description	Score	Implication
1	STAT2	signal transducer and activator of transcription 2, 113kDa	20.16	GeneCards inferred : Publications, Disorders, Drugs & Compounds (show sections)
2	IRF1	interferon regulatory factor 1	19.83	GeneCards inferred : Publications, Disorders (show sections)
3	IRF2	interferon regulatory factor 2	19.50	GeneCards inferred : Publications, Disorders (show sections)
4	STAT1	signal transducer and activator of transcription 1, 91kDa	19.17	GeneCards inferred : Publications, Drugs & Compounds, Disorders (show sections)
5	IFNA2	interferon, alpha 2	18.85	GeneCards inferred : Publications, Disorders (show sections)
6	NEU1	sialidase 1 (lysosomal sialidase)	18.52	GeneCards inferred : Disorders (show sections)
7	IL10RB	interleukin 10 receptor, beta	18.18	GeneCards inferred : Publications, Disorders (show sections)
8	MRC1	mannose receptor, C type 1	17.85	GeneCards inferred : Disorders (show sections)
9	CHMP4B	charged multivesicular body protein 4B	17.53	GeneCards inferred : Disorders (show sections)
10	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1	17.20	GeneCards inferred : Disorders (show sections)
11	EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	16.88	GeneCards inferred : Publications, Disorders (show sections)
12	IRF9	interferon regulatory factor 9	16.54	GeneCards inferred : Publications, Disorders (show sections)
13	DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58	16.22	GeneCards inferred : Disorders, Proteins (show sections)
14	BST2	bone marrow stromal cell antigen 2	15.89	GeneCards inferred : Publications, Disorders (show sections)
15	CHMP4A	charged multivesicular body protein 4A	15.56	GeneCards inferred : Disorders (show sections)
16	NDUFB4	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa	15.23	GeneCards inferred : Disorders (show sections)
17	ISG20	interferon stimulated exonuclease gene 20kDa	14.90	GeneCards inferred : Publications, Disorders (show sections)
18	UBQLN4	ubiquilin 4	14.58	GeneCards inferred : Publications, Disorders (show sections)
19	COPE	coatomer protein complex, subunit epsilon	14.25	GeneCards inferred : Disorders (show sections)
20	DPT	dermatopontin	13.92	GeneCards inferred : Disorders (show sections)
21	AIDA	axin interactor, dorsalization associated	13.59	GeneCards inferred : Disorders (show sections)
22	CD46	CD46 molecule, complement regulatory protein	13.26	GeneCards inferred : Publications, Disorders (show sections)
23	HLA-DPB1	major histocompatibility complex, class II, DP beta 1	12.94	GeneCards inferred : Publications, Disorders (show sections)
24	IFNAR2	interferon (alpha, beta and omega) receptor 2	12.61	GeneCards inferred : Publications, Disorders (show sections)
25	IFIH1	interferon induced with helicase C domain 1	12.28	GeneCards inferred : Disorders, Proteins (show sections)
26	HSF1	heat shock transcription factor 1	11.95	GeneCards inferred : Publications, Disorders (show sections)
27	CFB	complement factor B	11.62	GeneCards inferred : Publications, Disorders (show sections)
28	CXCL10	chemokine (C-X-C motif) ligand 10	11.30	GeneCards inferred : Publications, Disorders (show sections)
29	UMOD	uromodulin	10.97	GeneCards inferred : Publications, Disorders (show sections)
30	IL12RB2	interleukin 12 receptor, beta 2	10.64	GeneCards inferred : Publications, Disorders (show sections)
31	IL2RB	interleukin 2 receptor, beta	10.31	GeneCards inferred : Publications, Disorders (show sections)
32	IL4R	interleukin 4 receptor	9.99	GeneCards inferred : Publications, Disorders (show sections)
33	IL18R1	interleukin 18 receptor 1	9.66	GeneCards inferred : Publications, Disorders (show sections)
34	FADD	Fas (TNFRSF6)-associated via death domain	9.33	GeneCards inferred : Disorders (show sections)
35	AMOTL1	angiomotin like 1	9.00	GeneCards inferred : Disorders (show sections)
36	CD40LG	CD40 ligand	8.67	GeneCards inferred : Publications, Disorders (show sections)
37	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	8.35	GeneCards inferred : Publications, Disorders (show sections)
38	C3	complement component 3	8.02	GeneCards inferred : Publications, Disorders (show sections)
39	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	7.69	GeneCards inferred : Publications, Disorders (show sections)
40	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7.36	GeneCards inferred : Publications, Disorders (show sections)
41	IFNB1	interferon, beta 1, fibroblast	7.03	GeneCards inferred : Publications, Disorders (show sections)
42	AURKA	aurora kinase A	6.71	GeneCards inferred : Disorders (show sections)
43	IL2RA	interleukin 2 receptor, alpha	6.38	GeneCards inferred : Publications, Disorders (show sections)
44	HSPB1	heat shock 27kDa protein 1	6.05	GeneCards inferred : Publications, Disorders (show sections)
45	TPO	thyroid peroxidase	5.72	GeneCards inferred : Publications, Disorders (show sections)
46	IL1RN	interleukin 1 receptor antagonist	5.40	GeneCards inferred : Publications, Disorders (show sections)
47	IGHE	immunoglobulin heavy constant epsilon	5.07	GeneCards inferred : Publications, Disorders (show sections)
48	ICAM1	intercellular adhesion molecule 1	4.74	GeneCards inferred : Publications, Disorders (show sections)
49	HLA-DRB1	major histocompatibility complex, class II, DR beta 1	4.41	GeneCards inferred : Publications, Disorders (show sections)
50	CD4	CD4 molecule	4.08	GeneCards inferred : Disorders (show sections)

Products for genes related to Mumps disease:

id	Company	Proteins	Lysates	Antibodies
1	Novus Biologicals	49	49	50
2	LSBio	-	-	50

Genetic Variations for Mumps

Expression for genes affiliated with Mumps

Sources:
¹BioGPS, ¹⁵Gene Expression Omnibus DataSets
See all sources

Expression patterns in normal tissues for genes affiliated with Mumps

Search GEO for disease gene expression data for Mumps.

Pathways for genes affiliated with Mumps

Sources:
⁵¹QIAGEN, ²⁹KEGG, ³⁷NCBI BioSystems Database, ¹²EMD Millipore, ⁵³Reactome
See all sources

Pathways related to Mumps according to GeneCards/GeneDecks:

(show all 13)

id	Super pathways (with members indented)	Score	Top Affiliating Genes
1	IL-22 Pathway⁵¹	10.4	STAT1, IL10RB
2	Tuberculosis²⁹	10.4	IL10RB, MRC1
3	Interferon Pathway⁵¹	10.3	STAT2, STAT1, IFNA2
4	Osteoclast differentiation²⁹	10.3	IRF9, STAT2, STAT1
5	Type III interferon signaling³⁷	10.2	IRF9, STAT2, STAT1, IL10RB
6	Jak-STAT signaling pathway²⁹	10.2	IFNA2, IRF9, STAT2, STAT1, IL10RB
7	Immune response IFN gamma signaling pathway Hide members Immune response IFN gamma signaling pathway¹² IFN-gamma pathway³⁷	10.2	IRF9, IRF1, STAT2, EIF2AK2, STAT1
8	Influenza A²⁹ Hide members Measles²⁹ Herpes simplex infection²⁹	10.2	STAT1, IRF9, EIF2AK2, STAT2, IFNA2
9	Hepatitis C²⁹	10.1	IFNA2, IRF9, IRF1, STAT2, STAT1, EIF2AK2
10	Type II interferon signaling (IFNG)³⁷	10.1	IFNA2, IRF9, IRF1, IRF2, STAT2, STAT1
11	Immune response IFN alpha/beta signaling pathway Hide members Regulation of IFNA signaling⁵³ Interferon alpha/beta signaling⁵³ Immune response IFN alpha/beta signaling pathway¹²	10.1	IRF1, STAT1, ISG20, IRF9, IFNA2, STAT2
12	Interferon Signaling⁵³ Hide members ISG15 antiviral mechanism⁵³ Cytokine Signaling in Immune system⁵³ Antiviral mechanism by IFN-stimulated genes⁵³ Cytokine Signaling in Immune system⁵³ Interferon gamma signaling⁵³	10.0	ISG20, STAT2, IRF2, IFNA2, STAT1, EIF2AK2
13	Immune System⁵³ Hide members Adaptive Immune System⁵³ Innate Immune System⁵³	9.9	EIF2AK2, IFNA2, STAT1, IRF1, IRF2, ISG20

Compounds for genes affiliated with Mumps

Sources:
⁴⁴Novoseek, ⁴⁹PharmGKB, ¹¹DrugBank, ²⁴HMDB
See all sources

Compounds related to Mumps according to GeneCards/GeneDecks:

(show all 17)

id	Compound	Score	Top Affiliating Genes
1	mumps⁴⁴	10.6	STAT2, STAT1
2	cycloheximide⁴⁴	10.6	STAT1, IRF1
3	inosine monophosphate⁴⁴	10.5	EIF2AK2, STAT1, IRF1
4	polyinosinic-polycytidylic acid⁴⁴	10.5	IRF1, STAT1, EIF2AK2
5	ribavirin⁴⁴ ⁴⁹ ¹¹	12.4	IFNA2, ISG20, STAT1, NEU1, EIF2AK2
6	ifn-alpha⁴⁴	10.4	IFNA2, IRF9, IRF1, STAT2, STAT1, EIF2AK2
7	adenine⁴⁴ ¹¹ ²⁴	12.4	IRF9, IRF1, ISG20, EIF2AK2
8	poly(i-c)⁴⁴	10.4	IRF1, STAT1, EIF2AK2
9	galactose⁴⁴	10.4	NEU1, MRC1, IFNA2
10	levamisole⁴⁴ ¹¹	11.4	NEU1, IFNA2
11	2,5-oligoadenylate⁴⁴	10.3	EIF2AK2, IFNA2, IRF9, IRF1, IRF2, ISG20
12	retinoic acid⁴⁴ ²⁴	11.3	IFNA2, IRF9, IRF1, IRF2, STAT2, STAT1
13	amantadine⁴⁴ ¹¹	11.3	NEU1, IFNA2
14	oligonucleotide⁴⁴	10.2	EIF2AK2, STAT1, ISG20, IRF2, IRF1, IRF9
15	tyrosine⁴⁴	10.2	IFNA2, PDP1, IRF9, IRF1, IRF2, ISG20
16	serine⁴⁴	10.1	PDP1, IRF1, IRF2, STAT2, STAT1, NEU1
17	gliadin⁴⁴	10.1	STAT1, IRF1

GO Terms for genes affiliated with Mumps

Sources:
¹⁶Gene Ontology
See all sources

Cellular components related to Mumps according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	nucleoplasm	GO:005654	10.1	IRF1, IRF2, ISG20, STAT2, STAT1, IRF9
2	cytosol	GO:005829	9.5	EIF2AK2, COPE, UBQLN4, IRF9, IRF1, IRF2

Biological processes related to Mumps according to GeneCards/GeneDecks:

(show all 11)

id	Name	GO ID	Score	Top Affiliating Genes
1	regulation of type I interferon-mediated signaling pathway	GO:060338	10.5	STAT1, STAT2, IFNA2
2	interferon-gamma-mediated signaling pathway	GO:060333	10.4	IRF1, IRF9, IRF2, STAT1
3	cellular response to interferon-beta	GO:035458	10.4	IRF1, STAT1
4	negative regulation of viral genome replication	GO:045071	10.3	ISG20, BST2, EIF2AK2
5	response to virus	GO:009615	10.3	DHX58, EIF2AK2, BST2, ISG20
6	type I interferon-mediated signaling pathway	GO:060337	10.3	IRF1, STAT1, STAT2, IFNA2, IRF9, IRF2
7	cytokine-mediated signaling pathway	GO:019221	10.3	IRF1, ISG20, STAT1, IRF9, STAT2, IRF2
8	response to interferon-alpha	GO:035455	10.2	EIF2AK2, BST2
9	modulation by virus of host morphology or physiology	GO:019048	10.2	DHX58, STAT2, STAT1, EIF2AK2
10	defense response to virus	GO:051607	10.1	ISG20, BST2, IFNA2, IRF9, EIF2AK2, DHX58
11	regulation of innate immune response	GO:045088	10.1	DHX58, IRF1