MCID: MMP001
MIFTS: 56

Mumps malady

Categories: Rare diseases, Infectious diseases, Oral diseases

Aliases & Classifications for Mumps

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Summaries for Mumps

About this section
MedlinePlus:37 Mumps is an illness caused by the mumps virus. it starts with fever headache muscle aches tiredness loss of appetite after that, the salivary glands under the ears or jaw become swollen and tender. the swelling can be on one or both sides of the face. symptoms last 7 to 10 days. serious complications are rare. you can catch mumps by being with another person who has it. there is no treatment for mumps, but the measles-mumps-rubella (mmr) vaccine can prevent it. before the routine vaccination program in the united states, mumps was a common illness in infants, children and young adults. now it is a rare disease in the u.s. centers for disease control and prevention

MalaCards based summary: Mumps is related to sensorineural hearing loss and hepatitis b, and has symptoms including fever, headache and muscle aches. An important gene associated with Mumps is STAT2 (Signal Transducer And Activator Of Transcription 2), and among its related pathways are Interferon type I and CXCR4-mediated signaling events. Affiliated tissues include salivary gl, salivary gland and brain, and related mouse phenotypes are liver/biliary system and endocrine/exocrine gland.

Disease Ontology:11 A viral infectious disease that results in inflammation located in salivary gland, has material basis in Mumps virus, which is transmitted by droplet spread of saliva or mucus from the mouth, nose, or throat of an infected person, or transmitted by contaminated fomites. The infection has symptom fever, has symptom headache, has symptom muscle aches, has symptom tiredness, has symptom loss of appetite, has symptom swollen and tender salivary glands under the ears or jaw on one or both sides of the face.

CDC:2 Mumps is a contagious disease caused by a virus. It typically starts with a few days of fever, headache, muscle aches, tiredness, and loss of appetite, followed by swollen salivary glands. You can protect yourself and your family against mumps with vaccination.

Wikipedia:70 Mumps, also known as epidemic parotitis, is a viral disease caused by the mumps virus. Initial signs and... more...

Related Diseases for Mumps

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Diseases in the Mumps family:

Congenital Mumps

Diseases related to Mumps via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 294)
idRelated DiseaseScoreTop Affiliating Genes
1sensorineural hearing loss29.8HLA-DRB1, IFNG, TNF
2hepatitis b29.8IFNG, IL2RA, TNF
3chlamydia29.6CD40LG, STAT1, STAT2
4asthma28.1CD40LG, HLA-DPB1, HLA-DRB1, IFNG, IL2RA, TNF
5nervous system disease27.6CD46, IFNAR2, IFNG, IL2, IL2RA, STAT1
6congenital mumps11.9
7rubella11.4
8measles11.3
9endotheliitis11.1
10testicular microlithiasis10.7
11infections, recurrent, with encephalopathy, hepatic dysfunction, and cardiovasuclar malformations10.7
12male infertility10.7
13salivary gland disease10.7
14common variable immunodeficiency10.5HLA-DRB1, TNF
15weber syndrome10.5HLA-DRB1, TNF
16krieble bixler syndrome10.5HLA-DRB1, TNF
17panner disease10.4IFNG, TNF
18baetz-greenwalt syndrome10.4IFNG, TNF
19dentine erosion10.4IFNG, STAT1
20rhizomelic pseudopolyarthritis10.4HLA-DRB1, TNF
21autoimmune pancreatitis10.4IFNG, TNF
22endometrial stromal nodule10.4CD40LG, IFNG
23epstein-barr virus hepatitis10.4HLA-DRB1, TNF
24chronic polyneuropathy10.4HLA-DRB1, IFNG, STAT1
25abdominal chemodectomas with cutaneous angiolipomas10.4HLA-DRB1, TNF
26gonococcal bursitis10.4CD40LG, STAT1
27primary systemic mycosis10.4IFNG, TNF
28indian tick typhus10.3CD40LG, IFNG
29eye accommodation disease10.3IFNG, IL2RA
30motor peripheral neuropathy10.3IFNG, IL2RA
31gonococcal synovitis10.3IFNG, TNF
32multicentric castleman disease10.3HLA-DPB1, HLA-DRB1, IFNG
33night blindness10.3CD40LG, TNF
34lymphocytic colitis10.3HLA-DRB1, IFNG, TNF
35orchitis10.3
36mastocytosis cutaneous with short stature conductive hearing loss and microtia10.3HLA-DRB1, IFNG, TNF
37hemophagocytic lymphohistiocytosis10.3HLA-DRB1, IFNG, TNF
38parsonage turner syndrome10.3HLA-DPB1, HLA-DRB1, TNF
39myopathy-growth delay-intellectual disability-hypospadias syndrome10.2HLA-DPB1, HLA-DRB1, TNF
40meningitis10.2
41lens-induced iridocyclitis10.2CD40LG, HLA-DPB1
42crohn's colitis10.2IL2RA, TNF
43adult malignant hemangiopericytoma10.2HLA-DRB1, IFNG, TNF
44dermatitis herpetiformis, familial10.2CD40LG, HLA-DRB1, IFNG
45intermittent proptosis10.2HLA-DRB1, IFNG, TNF
46chronic hiccups10.2IFNG, IL2RA
47aseptic meningitis10.2
48ileocolitis10.2CD40LG, TNF
49allergic hypersensitivity disease10.2CD40LG, HLA-DRB1, TNF
50chronic apical periodontitis10.2CD40LG, HLA-DRB1, TNF

Graphical network of the top 20 diseases related to Mumps:



Diseases related to mumps

Symptoms for Mumps

About this section

Symptoms:

 11 (show all 6)
  • fever
  • headache
  • muscle aches
  • tiredness
  • loss of appetite
  • swollen

UMLS symptoms related to Mumps:


pruritus

Drugs & Therapeutics for Mumps

About this section

Drugs for Mumps (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 39)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1VaccinesPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 16428
2AntibodiesPhase 4, Phase 2, Phase 16045
3ImmunoglobulinsPhase 4, Phase 2, Phase 16045
4Pharmaceutical SolutionsPhase 4, Phase 3, Phase 27793
5Heptavalent Pneumococcal Conjugate VaccinePhase 4, Phase 3, Phase 2454
6Liver ExtractsPhase 43868
7
Tetracyclineapproved, vet_approvedPhase 39960-54-85353990
Synonyms:
(-)-Tetracycline
(4S,4AS,5as,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
6-Methyl-1,11-dioxy-2-naphthacenecarboxamide
60-54-8
64-75-5 (mono-hydrochloride)
6591-49-7
87128_FLUKA
87128_SIGMA
AC-13151
AC1L1KAT
AC1NQXT7
AC1NRDAM
AC1NS4RQ
AC1NSDX8
AC1NTUT2
AC1NUZHL
AC1O52HS
Abramycin
Abricycline
Achromycin
Achromycin (naphthacene derivative)
Achromycin V
Achromycin, naphthacene derivative
Agromicina
Ambramicina
Ambramycin
Amycin
Anhydrotetracycline
BIDD:GT0653
BPBio1_000242
BSPBio_000220
BSPBio_001950
Bio-tetra
Biocycline
Bristaciclin
Bristaciclin .alpha.
Bristaciclina
Bristacycline
C06570
CHEBI:27902
CHEMBL1440
CID12309720
CID5280962
CID5289435
CID5353990
CID5359245
CID5388997
CID5412
CID5497101
CID6426717
Cefracycline
Cefracycline suspension
Centet (base)
Ciclibion
Copharlan
Criseociclina
Cyclomycin
Cyclopar
Cytome
D00201
DB00759
Democracin
Deschlorobiomycin
DivK1c_000827
Dumocyclin
EINECS 200-481-9
Enterocycline
HMS2090B04
HSDB 3188
Hostacyclin
IDI1_000827
KBio1_000827
KBio2_001514
KBio2_004082
KBio2_006650
KBio3_001450
KBioGR_000783
KBioSS_001514
LS-187078
LS-93869
Lemtrex (base)
Lexacycline
Limecycline
Liquamycin
Liquamycin (Veterinary)
 
Liquamycin, veterinary
MLS000069728
Medocycline
Mericycline
Micycline
MolPort-001-794-633
MolPort-003-983-460
MolPort-005-934-198
NCGC00161665-01
NINDS_000827
NSC 108579
NSC108579
Neocycline
Omegamycin
Orlycycline
Panmycin
Piracaps (base)
Polycycline
Polycycline (VAN)
Polycycline (antibiotic)
Polycycline, antibiotic
Polyotic
Prestwick0_000140
Prestwick1_000140
Prestwick2_000140
Prestwick3_000140
Purocyclina
Resteclin
Robitet
Roviciclina
SK-Tetracycline
SMR000058220
SPBio_001457
SPBio_002159
STOCK1N-42738
Sanclomycine
Solvocin
Spectrum2_001329
Spectrum3_000565
Spectrum4_000352
Spectrum5_001112
Spectrum_001034
Sumycin
Sumycin (TN)
Sumycin syrup
T-125
T3258_SIGMA
Tetra-Co
Tetrabon
Tetrachel
Tetraciclina
Tetraciclina [INN-Spanish]
Tetracycl
Tetracyclin
Tetracycline & VRC3375
Tetracycline (JAN/USP/INN)
Tetracycline (internal use)
Tetracycline Free Base
Tetracycline HCl
Tetracycline I
Tetracycline II
Tetracycline Monohydrochloride
Tetracycline [USAN:INN:BAN:JAN]
Tetracyclinum
Tetracyclinum [INN-Latin]
Tetracyn
Tetradecin
Tetrafil
Tetraverine
Tetrazyklin
Topicycline
Tsiklomistsin
Tsiklomitsin
Tétracycline
UNII-F8VB5M810T
UPCMLD-DP127
UPCMLD-DP127:001
UPCMLD-DP127:002
Veracin
Vetacyclinum
Vetquamycin-324 (free base)
WLN: L E6 C666 BV FV CU GUTTT&J DQ EQ GVZ HQ IN1&1 MQ M1 RQ
component of Tetrastatin
methyl-1,11-dioxo-2-naphthacenecarboxamide
nchembio.273-comp1
nchembio.289-comp1
tetracycline
8
Aluminum hydroxideapprovedPhase 3, Phase 220121645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
9PENTAPhase 3, Phase 2109
10Anti-Infective AgentsPhase 321402
11Anti-Bacterial AgentsPhase 310884
12
LactitolPhase 3, Phase 2332585-86-43871
Synonyms:
4-O-b-D-Galactopyranosyl-D-glucitol, 9CI
E966
Emportal
 
Floralac
Importal
Oponaf
Portolac
13
Daclizumabapproved, investigationalPhase 298152923-56-3
Synonyms:
 
Dacliximab
Daclizumab beta
14
AltretamineapprovedPhase 259645-05-62123
Synonyms:
2,4, 6-Tris(dimethylamino)-1,3,5-triazine
2,4,6-Tris(dimethylami
2,4,6-Tris(dimethylamino)-1,3,5-triazine
2,4,6-Tris(dimethylamino)-S-triazine
2,4,6-Tris(dimethylamino)-s-triazine
2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine
549835_ALDRICH
645-05-6
A 8723
A0567/0026158
A8723_SIGMA
AB00052308
AC-12006
AC1L1CYX
AI3-50852
AKOS001729401
Altretamin
Altretamina
Altretamina [INN-Spanish]
Altretamine (USP/INN)
Altretamine Bellon Brand
Altretamine Chiesi Brand
Altretamine Wassermann Brand
Altretamine [USAN:INN:BAN]
Altretaminum
Altretaminum [INN-Latin]
Altrétamine
BPBio1_001004
BRD-K67043667-001-04-1
BRN 0195058
BSPBio_000912
Bellon Brand of Altretamine
C9H18N6
CAS-654-05-6
CCRIS 5492
CHEBI:24564
CHEMBL1455
CID2123
CPD000058181
ChemDiv2_005185
Chiesi Brand of Altretamine
D006585
D02841
DB00488
DivK1c_000772
EINECS 211-428-4
ENT 50852
EU-0100083
FT-0083576
HEXAMETHYLMELAMINE
HMM
HMS1383L15
HMS1570N14
HMS1922C05
HMS2090G17
HMS2092H16
HMS502G14
HSDB 7559
HTM
HXM
Hemel
Hexalen
Hexalen (TN)
Hexalen, Altretamine
 
Hexamethylmelamine
Hexastat
Hexinawas
I06-0604
IDI1_000772
IDI1_003900
InChI=1/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H
KB-913
KBio1_000772
KBio2_001788
KBio2_004356
KBio2_006924
KBio3_002042
KBioGR_001388
KBioSS_001788
LS-1549
Lopac-A-8723
Lopac0_000083
MGI Pharma Brand of Altretamine
MLS000069621
MLS001076123
MolPort-002-111-210
N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine
NC 195
NCGC00015100-01
NCGC00015100-02
NCGC00015100-03
NCGC00015100-06
NCGC00015100-11
NCGC00021216-03
NCGC00021216-04
NCGC00021216-05
NCGC00021216-06
NCGC00021216-07
NCI-C50259
NCI60_000871
NINDS_000772
NSC 13875
NSC-13875
NSC13875
N~2~,N~2~,N~4~,N~4~,N~6~,N~6~-Hexamethyl-1,3,5-triazine-2,4,6-triamine
Prestwick0_000946
Prestwick1_000946
Prestwick2_000946
Prestwick3_000946
Rhone Poulenc Rorer Brand of Altretamine
Rhone-Poulenc Rorer Brand of Altretamine
S1278_Selleck
SAM002564241
SMR000058181
SPBio_000754
SPBio_003071
SPECTRUM1503065
ST086739
STK749184
Spectrum2_000907
Spectrum3_000951
Spectrum4_001064
Spectrum5_001092
Spectrum_001308
UNII-Q8BIH59O7H
WLN: T6N CN ENJ BN1&1 DN1&1 FN1&1
Wassermann Brand of Altretamine
ZINC00000905
altretamine
no)-s-triazine
15Immunoglobulin GPhase 2265
16Immunosuppressive AgentsPhase 212770
17Interleukin-2Phase 2553
18AnticoagulantsPhase 22516
19Fibrinolytic AgentsPhase 22317
20Antibodies, MonoclonalPhase 23795
21
Acetylcholineapproved77651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
22
Adalimumabapproved478331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
23
Methotrexateapproved15181959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
24
Infliximabapproved378170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
25
Azathioprineapproved165446-86-62265
Synonyms:
446-86-6
55774-33-9 (hydrochloride salt)
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]
6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine
6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine
6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
6-(Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(Methyl-p-nitro-5-imidazolyl)thiopurine
6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine
6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine
6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine
6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
A 4638
A2593_SIAL
A4638_SIAL
A4638_SIGMA
AB00443544
AB00443544-03
AC-4230
AC1L1DAL
AC1Q3Z1F
AI-981/34845012
AI3-50290
Azamun
Azamun [Czech]
Azanin
Azasan
Azasan (TN)
Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine
Azathioprin
Azathioprine (JP15/USP/INN)
Azathioprine Sodium
Azathioprine [USAN:INN:BAN:JAN]
Azathioprine sodium
Azathioprinum
Azathioprinum [INN-Latin]
Azathiopurine
Azatioprin
Azatioprina
Azatioprina [INN-Spanish]
Azothioprine
B. W. 57-322
BPBio1_000054
BRD-K32821942-001-05-6
BRD-K60324116-001-01-5
BSPBio_000048
BSPBio_001876
BW 57-322
BW 57322
BW-57-322
C06837
C9H7N7O2S
CAS-446-86-6
CBDivE_013132
CCRIS 62
CHEBI:2948
CHEMBL1542
CID2265
CPD000427366
Ccucol
ChemDiv1_002659
Cytostatics
D00238
DB00993
DivK1c_000586
EINECS 207-175-4
EU-0100027
FT-0083532
HMS1568C10
HMS1920E17
 
HMS2091K19
HMS501N08
HMS594I19
HSDB 7084
IDI1_000586
Immuran
Imuran
Imuran (TN)
Imuran (tn)
Imurek
Imurel
KBio1_000586
KBio2_000464
KBio2_002427
KBio2_003032
KBio2_004995
KBio2_005600
KBio2_007563
KBio3_001376
KBio3_002906
KBioGR_000646
KBioGR_002427
KBioSS_000464
KBioSS_002433
LS-123
Lopac-A-4638
Lopac0_000027
MLS001049307
Methylnitroimidazolylmercaptopurine
MolPort-000-745-914
MolPort-000-764-262
MolPort-003-665-485
Muran
NCGC00015060-01
NCGC00015060-02
NCGC00015060-04
NCGC00015060-12
NCGC00090836-01
NCGC00090836-02
NCGC00090836-03
NCGC00090836-04
NCGC00090836-05
NCGC00090836-06
NCGC00094593-01
NCGC00094593-02
NCGC00094593-03
NCI-C03474
NINDS_000586
NSC 39084
NSC-39084
NSC39084
Oprea1_375441
Oprea1_533384
Oprea1_633462
Prestwick0_000094
Prestwick1_000094
Prestwick2_000094
Prestwick3_000094
Prestwick_41
S1721_Selleck
SAM002589938
SDCCGMLS-0065415.P001
SMR000427366
SPBio_000255
SPBio_001987
SPECTRUM1500133
STK831906
STOCK1S-20293
STOCK1S-27186
Spectrum2_000068
Spectrum3_000308
Spectrum4_000243
Spectrum5_000848
Spectrum_000064
Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl)
UNII-MRK240IY2L
WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW
ZINC04258316
[Methyl(nitroimidazolyl)mercaptopurine]
azathioprine
azatiopr in
cMAP_000046
26
Certolizumab pegolapproved122428863-50-7
Synonyms:
428863-50-7
CDP870
Certolizumab pegol
 
Certolizumab pegol (USAN/INN)
Certolizumab pegol (genetical recombination)
Certolizumab pegol (genetical recombination) (JAN)
D03441
cimzia
27Peripheral Nervous System Agents22776
28Anti-HIV Agents3100
29onabotulinumtoxinA626
30Neuromuscular Agents1129
31Neurotransmitter Agents17734
32Botulinum Toxins, Type A630
33Cholinergic Agents3846
34abobotulinumtoxinA626
35incobotulinumtoxinA635
36Botulinum Toxins669
37Adjuvants, Immunologic2484
386-Mercaptopurine199
39AcidophilusNutraceutical518

Interventional clinical trials:

(show top 50)    (show all 122)
idNameStatusNCT IDPhase
1The Safety and Immunogenicity Study of Rotavirus Vaccine Simultaneously Vaccinated With MR or MMR VaccineUnknown statusNCT02153866Phase 4
2Immunogenicity and Safety of Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox DiseasesCompletedNCT00126997Phase 4
3Safety and Efficacy of Measles, Mumps, Rubella Vaccination in Juvenile Idiopathic ArthritisCompletedNCT00731965Phase 4
4Comparative Study of the Immunogenicity of MMR (Measles, Mumps and Rubella) Single Dose and Multidose PresentationsCompletedNCT01777529Phase 4
5Measles, Mumps, and Rubella (MMR) Immunity in College StudentsCompletedNCT00962819Phase 4
6Immunogenicity and Safety of Hepatitis A Vaccine Given at the Same Time of Measles, Mumps, Rubella Combined VaccineCompletedNCT00313950Phase 4
7MMR Vaccination Among HIV-infected AdultsCompletedNCT02724852Phase 4
8Concomitant Use of Hepatitis A Vaccine With Measles, Mumps, Rubella and Varicella Vaccine and Pneumococcal 7-Valent Conjugate Vaccine in Healthy 12-Month-Old Children (V251-067)CompletedNCT00312858Phase 4
9Assess GSK Biologicals' MMR Vaccine (Priorix) When Given to Healthy Children at the Age of 12 to 18 Months in Singapore.CompletedNCT00388440Phase 4
10MMR and Varicella Vaccine in Premature InfantsCompletedNCT00156559Phase 4
11Safety & Immunogenicity of MMR Vaccine by DSJI to That by Needle-Syringe in 15-18 Months Old ChildrenCompletedNCT02253407Phase 4
12Safety Study of a Refrigerator-Stable Formulation of VARIVAX®CompletedNCT00432731Phase 4
13Study of the Influence of Vaccination in HIV Viral Load and Immunologic Responses Against HIVCompletedNCT00329251Phase 4
14Immunogenicity and Safety of Japanese Encephalitis Vaccine When Given With Measles-Mumps-Rubella VaccineRecruitingNCT02880865Phase 4
15Homeopathic Vaccine TrialRecruitingNCT02825368Phase 4
16Induction of Immunity Against Measles in Pediatric Liver Transplant RecipientsRecruitingNCT01770119Phase 4
17Search for the Measles Vaccine Virus Excretion in Breast Milk of Breastfeeding Women After Postpartum Vaccination With MMRActive, not recruitingNCT02325310Phase 4
18Responses of Premature Infants to Measles-Mumps-Rubella (MMR) and Varicella VaccinesTerminatedNCT00138255Phase 4
19Immunogenicity and Reactogenicity of a Trivalent MMR (Trivivac) in Healthy InfantsUnknown statusNCT01763268Phase 2, Phase 3
20A Study of An Approved Vaccine at Mumps Expiry Potency in Healthy Children 12 to 18 Months of Age (V205C-007)(COMPLETED)CompletedNCT00092391Phase 3
21Immunogenicity and Safety of a Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox DiseasesCompletedNCT00127023Phase 3
22Immunogenicity and Safety of a Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox DiseasesCompletedNCT00127010Phase 3
23Immunogenicity and Safety of GSK Biologicals' Combined Measles-mumps-rubella Vaccine in Volunteers, Seven Years of Age and OlderCompletedNCT02058563Phase 3
24Study of Japanese Encephalitis Chimeric Virus Vaccine Given With Measles-Mumps-Rubella Vaccine in Taiwanese ToddlersCompletedNCT01188343Phase 3
25Safety, Tolerability, and Immunogenicity of Measles, Mumps, Rubella, and Varicella (MMRV) Vaccine Made With an Alternative Manufacturing Process (AMP)(V221-027)CompletedNCT01536405Phase 3
26Study to Evaluate Frozen Versus Refrigerated MMRV (Combined Measles, Mumps, Rubella, and Varicella) Investigational Vaccine (V221-016)CompletedNCT00092430Phase 3
27Study of Immunogenicity, Reactogenicity and Safety of the Combined Measles, Mumps and Rubella Vaccine Produced by Bio-Manguinhos/Fiocruz in Children 12-15 Months of Age, Followed by Tetraviral Vaccine in Children 15-18 Months.CompletedNCT01991899Phase 3
28Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Combined Measles-mumps-rubella (MMR) Vaccine in Children in Their Second Year of LifeCompletedNCT01681992Phase 3
29Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' Measles, Mumps and Rubella (MMR) Vaccine (209762) Compared to Merck & Co., Inc.'s MMR Vaccine in Healthy Children 12 to 15 Months of AgeCompletedNCT02184572Phase 3
30Immunogenicity & Safety Study of GSK Biologicals' Combined Measles-mumps-rubella-varicella Vaccine 208136CompletedNCT00751348Phase 3
31Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Combined Measles-mumps-rubella (MMR) Vaccine in Subjects Four to Six Years of AgeCompletedNCT01621802Phase 3
32Trial to Assess Safety, Tolerability, and Immunogenicity of Influenza Virus Vaccine, Trivalent, Types A & B, Live Cold-Adapted (FluMist) and Measles, Mumps, Rubella, and Varicella Vaccines Administered Concurrently to Healthy ChildrenCompletedNCT00192491Phase 3
33Immunogenicity & Safety of Hepatitis A Vaccine Co-admin With a Measles/Mumps/Rubella & a Varicella Vaccine in ChildrenCompletedNCT00197015Phase 3
34Evaluate Vaccine Against Chickenpox and a Combined Vaccine Against 4 Viral Childhood Diseases: Measles, Mumps, Rubella and ChickenpoxCompletedNCT00226499Phase 3
35ProQuad™ Versus M-M-R II™ and VARIVAX™ in Healthy Children (V221-009)(COMPLETED)CompletedNCT00975507Phase 3
36Comparison of GSK Measles-mumps-rubella-varicella (MMRV) Vaccine Versus PriorixTMCompletedNCT00969436Phase 3
37Immunogenicity and Safety Study of PriorixTetra™ When Co-administered With Conjugated MenC Vaccine in Healthy ChildrenCompletedNCT01506193Phase 3
38ProQuad® rHA SafetyCompletedNCT00560755Phase 3
39Immunogenicity and Safety Study of Proquad® and Infanrix® Hexa When Administered ConcomitantlyCompletedNCT00432042Phase 3
40Long-term Follow-up on Immunogenicity & Safety of Measles-Mumps-Rubella-Varicella (MMRV) Combined VaccineCompletedNCT00406211Phase 3
41Hepatitis A Vaccine, Inactivated and Measles, Mumps, Rubella and Varicella Virus Vaccine Live Safety StudyCompletedNCT00326183Phase 3
42Consistency Study of GlaxoSmithKline (GSK) Biologicals' MMR Vaccine (209762) (Priorix®) Comparing Immunogenicity and Safety to Merck & Co., Inc.'s MMR Vaccine (M M R®II), in Children 12 to 15 Months of AgeCompletedNCT01702428Phase 3
43Safety, Tolerability, and Immunogenicity of 3 Frozen ProQuad Consistency Lots in Healthy Children (V221-012)(COMPLETED)CompletedNCT00985153Phase 3
44A Study of ProQuad in Healthy 4 to 6 Year Old Children (V221-014)CompletedNCT00985166Phase 3
45Immunogenicity and Safety of Pediatric Vaccines When Administered With Menactra® in Healthy ToddlersCompletedNCT00422292Phase 3
46ProQuad® Intramuscular vs SubcutaneousCompletedNCT00402831Phase 3
47Immunogenicity and Safety of Concomitant Administration of MMR™ rHA and VARIVAX® by Intramuscular Versus Subcutaneous RouteCompletedNCT00432523Phase 3
48Comparative Study of Immunogenicity and Safety of a 2-Dose Regimen of ProQuad® Manufactured With rHACompletedNCT00566527Phase 3
49Immunogenicity and Safety of Kinrix + (Measles Mumps Rubella) MMR Vaccine With and Without Varicella Vaccine in Healthy Children 4-6 YearsCompletedNCT00871117Phase 3
50V221 Concomitant Use Study With Pneumococcal Conjugate Vaccine (V221-019)CompletedNCT00109343Phase 3

Search NIH Clinical Center for Mumps


Cochrane evidence based reviews: mumps

Genetic Tests for Mumps

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Anatomical Context for Mumps

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MalaCards organs/tissues related to Mumps:

35
Salivary gland, Brain, Testes, Liver, B cells, Skin, Heart

FMA organs/tissues related to Mumps:

17
Salivary gl

Animal Models for Mumps or affiliated genes

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MGI Mouse Phenotypes related to Mumps:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.0IFNG, IL10RB, IL12RB2, IL2, STAT1, TNF
2MP:00053798.7CD40LG, IFNG, IL10RB, IL12RB2, IL2, STAT1
3MP:00053818.4IFNG, IL10RB, IL12RB2, IL2, IL2RA, STAT1
4MP:00020068.3IFNAR2, IFNG, IL12RB2, IL2, STAT1, TNF
5MP:00107687.4CD40LG, IFNAR2, IFNG, IL10RB, IL2, IL2RA
6MP:00053977.2CD40LG, IFNAR2, IFNG, IL10RB, IL12RB2, IL2
7MP:00053877.2CD40LG, IFNAR2, IFNG, IL10RB, IL12RB2, IL2

Publications for Mumps

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Articles related to Mumps:

(show top 50)    (show all 793)
idTitleAuthorsYear
1
Challenges in interpreting diagnostic test results in a mumps outbreak in a highly vaccinated population. (28003216)
2016
2
Emerging mumps infection. (27097351)
2016
3
A Case of Anesthesia Mumps with Electroconvulsive Therapy. (27922460)
2016
4
Mumps Virus: Modification of the Identify-Isolate-Inform Tool for Frontline Healthcare Providers. (27625709)
2016
5
Immunogenicity and safety of early vaccination with two doses of a combined measles-mumps-rubella-varicella vaccine in healthy Indian children from 9a88months of age: a phase III, randomised, non-inferiority trial. (26362659)
2015
6
Seroprevalence of measles, mumps and rubella among young adults, after 20A years of universal two-dose MMR vaccination in Israel. (25891446)
2015
7
Measles-Mumps-Rubella-Varicella Combination Vaccine (ProQuad(Ar)): A Guide to Its Use in Children in the EU. (25732634)
2015
8
Vestibular dysfunction in patients with post-mumps sensorineural hearing loss. (25776266)
2015
9
Mumps outbreak in the Federation of Bosnia and Herzegovina with large cohorts of susceptibles and genetically diverse strains of genotype G, Bosnia and Herzegovina, December 2010 to September 2012. (25166347)
2014
10
Mumps vaccine effectiveness and risk factors for disease in households during an outbreak in New York City. (24252695)
2014
11
Seroprevalence survey on measles, mumps, rubella and varicella antibodies in healthcare workers in Japan: sex, age, occupational-related differences and vaccine efficacy. (23574767)
2014
12
Risk Factors for Transmission of Mumps in a Highly Vaccinated Population in Orange County, NY, 2009-2010. (23995590)
2014
13
Outbreak-related mumps vaccine effectiveness among a cohort of children and of young adults in Germany 2011. (24091837)
2013
14
Characterisation of mumps virus genotype C among patients with mumps in India. (23883719)
2013
15
Quantification of measles, mumps and rubella viruses using real-time quantitative TaqMan-based RT-PCR assay. (23018058)
2013
16
Spermiogram part of population with the manifest orchitis during an ongoing epidemic of mumps. (22937687)
2012
17
Establishment of a standard seed lot system of an Iranian Mumps virus strain; RS-12, for mass production of mumps and MMR vaccines. (23115712)
2012
18
Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations? (22687578)
2012
19
Immunogenicity and safety of a quadrivalent meningococcal conjugate vaccine administered concomitantly with measles, mumps, rubella, varicella vaccine in healthy toddlers. (22504039)
2012
20
Mumps exposure of a health care provider working in a neonatal intensive care unit leads to a hospital-wide effort that prevented an outbreak. (21641085)
2011
21
Anaphylactic reactions to measles-mumps-rubella vaccine in three children with allergies to hen's egg and cow's milk. (21244488)
2011
22
Mumps in prison: description of an outbreak in Manitoba, Canada. (22032098)
2011
23
Gene-specific contributions to mumps virus neurovirulence and neuroattenuation. (21543475)
2011
24
A 176 amino acid polypeptide derived from the mumps virus HN ectodomain shows immunological and biological properties similar to the HN protein. (20727167)
2010
25
Lower long-term immunogenicity of mumps component after MMR vaccine. (20975455)
2010
26
Measles-mumps-rubella-varicella combination vaccine and the risk of febrile seizures. (20587679)
2010
27
Closer look at autism and the measles-mumps-rubella vaccine. (21071320)
2010
28
Role of laboratory in rapid diagnosis of atypical mumps. (20563452)
2010
29
Assessment of humoral and cell-mediated immune response to measles-mumps-rubella vaccine viruses among patients with asthma. (21708062)
2010
30
Mumps control today. (20662719)
2010
31
An office-based prospective study of deafness in mumps. (19209100)
2009
32
Immunogenicity and safety of measles-mumps-rubella-varicella (MMRV) vaccine followed by one dose of varicella vaccine in children aged 15 months-2 years or 2-6 years primed with measles-mumps-rubella (MMR) vaccine. (19007835)
2009
33
Mumps: not an innocent bystander in solid organ transplantation. (19563333)
2009
34
Immunogenicity and safety of concomitant administration of a measles, mumps and rubella vaccine (M-M-RvaxPro) and a varicella vaccine (VARIVAX) by intramuscular or subcutaneous routes at separate injection sites: a randomised clinical trial. (19366435)
2009
35
Mumps outbreak on the island of Anglesey, North Wales, December 2008-January 2009. (19215718)
2009
36
Updated recommendations for isolation of persons with mumps. (18846033)
2008
37
Mumps epidemiology and immunity: the anatomy of a modern epidemic. (18820583)
2008
38
Mumps: a resurgent disease with protean manifestations. (18928441)
2008
39
An increase in the number of mumps cases in the Czech Republic, 2005-2006. (18768117)
2008
40
Mumps outbreak in a highly vaccinated school population: assessment of secondary vaccine failure using IgG avidity measurements. (17498856)
2007
41
Assessing participation bias in a population-based study of measles-mumps-rubella vaccine immunity in children and adolescents aged 12-18. (17564596)
2007
42
Comparison of the safety and immunogenicity of a refrigerator-stable versus a frozen formulation of ProQuad (measles, mumps, rubella, and varicella virus vaccine live). (17502347)
2007
43
Human leukocyte antigen class II alleles and rubella-specific humoral and cell-mediated immunity following measles-mumps-rubella-II vaccination. (15655774)
2005
44
Mumps virus-associated hemophagocytic syndrome. (15759337)
2005
45
Mumps epididymo-orchitis with prolonged detection of virus in semen and the development of anti-sperm antibodies. (15042662)
2004
46
Surveillance of measles-mumps-rubella vaccine-associated aseptic meningitis in Germany. (12478324)
2002
47
Phenotype distribution of the third component of complement (C3) and of the properdin B factor (BF) in children with mumps meningitis. (8399122)
1993
48
Mumps pancreatitis without parotitis. (4692679)
1973
49
LEUKEMOID REACTION TO MUMPS VIRUS. (14160741)
1964
50
Mumps meningoencephalitis with and without parotitis. (18147966)
1949

Variations for Mumps

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Expression for genes affiliated with Mumps

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Search GEO for disease gene expression data for Mumps.

Pathways for genes affiliated with Mumps

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Pathways related to Mumps according to GeneCards Suite gene sharing:

(show all 47)
idSuper pathwaysScoreTop Affiliating Genes
19.7IFNAR2, STAT1, STAT2
29.5HLA-DRB1, STAT1, STAT2
39.4IFNG, IL2, STAT1
49.3IFNAR2, IFNG, IL2
5
Show member pathways
9.3IFNAR2, IL10RB, STAT1, STAT2
69.3IFNAR2, IFNG, STAT1, STAT2
79.2IFNG, STAT1, TNF
89.2CD40LG, IFNG, TNF
99.2IFNAR2, STAT1, STAT2, TNF
109.2IFNG, IRF2, STAT1, STAT2
11
Show member pathways
9.1IFNG, IL12RB2, IL2RA
129.1IFNG, IL2, TNF
139.0CD40LG, IL2RA, TNF
148.7IFNG, IL2, IRF2, TNF
158.7IFNAR2, IFNG, STAT1, STAT2, TNF
168.7CD40LG, IFNG, IL2, IL2RA
178.7IFNG, IL12RB2, IL2, IL2RA
18
Show member pathways
8.6CD40LG, HLA-DRB1, IL2, IL2RA
198.6HLA-DRB1, IFNG, IL2, TNF
208.5HLA-DRB1, IFNG, IL2, IL2RA
21
Show member pathways
8.5IFNG, IL2, IL2RA, TNF
228.5IFNG, IL2, IL2RA, TNF
23
Show member pathways
8.5IFNG, IL10RB, IL2, STAT1, TNF
24
Show member pathways
8.3IFNAR2, IFNG, IL2, STAT1, STAT2, TNF
258.3HLA-DPB1, HLA-DRB1, IFNG, IL10RB
26
Show member pathways
8.3IFNG, IL12RB2, IL2, STAT1, STAT2, TNF
27
Show member pathways
8.2IFNAR2, IFNG, IL2, IL2RA, TNF
28
Show member pathways
8.2CD40LG, IFNG, IL2, IL2RA, TNF
298.2IFNG, IL12RB2, IL2, IL2RA, TNF
308.2HLA-DPB1, HLA-DRB1, IFNG, TNF
31
Show member pathways
8.1IFNG, IL10RB, IL2, IL2RA, STAT1, STAT2
32
Show member pathways
8.0IFNAR2, IFNG, IL2, IRF2, STAT1, STAT2
33
Show member pathways
7.9HLA-DRB1, IFNG, IL12RB2, IL2, IL2RA, STAT1
347.6HLA-DPB1, HLA-DRB1, IL2, IL2RA, TNF
35
Show member pathways
7.6HLA-DPB1, HLA-DRB1, IFNAR2, IFNG, IRF2, STAT1
367.5IFNAR2, IFNG, IL10RB, IL12RB2, IL2, IL2RA
377.5HLA-DPB1, HLA-DRB1, IFNG, IL10RB, STAT1, TNF
38
Show member pathways
7.5CD40LG, IL10RB, IL12RB2, IL2, IL2RA, STAT1
39
Show member pathways
7.4HLA-DRB1, IFNG, IL2, IL2RA, STAT1, STAT2
40
Show member pathways
7.2CD40LG, HLA-DPB1, HLA-DRB1, IFNG, IL10RB, STAT1
41
Show member pathways
7.2CD40LG, IFNAR2, IFNG, IL10RB, IL12RB2, IL2
42
Show member pathways
7.0IFNAR2, IFNG, IL10RB, IL12RB2, IL2, IL2RA
437.0CD40LG, CD46, IFNG, IL2, IL2RA, IRF2
44
Show member pathways
6.9CD40LG, HLA-DPB1, HLA-DRB1, IFNG, IL12RB2, IL2
45
Show member pathways
6.0CD46, HLA-DPB1, HLA-DRB1, IFNAR2, IFNG, IL2
46
Show member pathways
5.9CD40LG, HLA-DPB1, HLA-DRB1, IFNAR2, IFNG, IL10RB
47
Show member pathways
4.7CD40LG, CD46, HLA-DPB1, HLA-DRB1, IFNAR2, IFNG

GO Terms for genes affiliated with Mumps

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Cellular components related to Mumps according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:00426139.8HLA-DPB1, HLA-DRB1
2external side of plasma membraneGO:00098978.7CD40LG, IFNG, IL12RB2, IL2RA, TNF
3intracellularGO:00056228.6CD40LG, IFNAR2, IFNG, IL2RA, TNF
4cell surfaceGO:00099867.5CD40LG, CD46, HLA-DPB1, HLA-DRB1, IL2RA, TNF
5plasma membraneGO:00058866.2CD40LG, CD46, HLA-DPB1, HLA-DRB1, IFNAR2, IL10RB

Biological processes related to Mumps according to GeneCards Suite gene sharing:

(show all 27)
idNameGO IDScoreTop Affiliating Genes
1response to interferon-betaGO:003545610.6IFNAR2, STAT1
2regulation of interferon-gamma-mediated signaling pathwayGO:006033410.3IFNG, STAT1
3positive regulation of regulatory T cell differentiationGO:004559110.3CD46, IL2
4regulation of type I interferon-mediated signaling pathwayGO:006033810.3IFNAR2, STAT1, STAT2
5regulation of immunoglobulin secretionGO:005102310.2CD40LG, TNF
6JAK-STAT cascadeGO:000725910.2IFNAR2, STAT1, STAT2
7positive regulation of isotype switching to IgG isotypesGO:004830410.2IFNG, IL2
8regulation of T cell homeostatic proliferationGO:004601310.2IL2, IL2RA
9negative regulation of lymphocyte proliferationGO:005067210.1IL2, IL2RA
10positive regulation of vitamin D biosynthetic processGO:006055710.1IFNG, TNF
11positive regulation of calcidiol 1-monooxygenase activityGO:006055910.1IFNG, TNF
12positive regulation of membrane protein ectodomain proteolysisGO:005104410.1IFNG, TNF
13positive regulation of chemokine biosynthetic processGO:004508010.1IFNG, TNF
14positive regulation of osteoclast differentiationGO:004567210.0IFNG, TNF
15type I interferon signaling pathwayGO:006033710.0IFNAR2, IRF2, STAT1, STAT2
16tumor necrosis factor-mediated signaling pathwayGO:00332099.9CD40LG, STAT1, TNF
17negative regulation of growth of symbiont in hostGO:00441309.9IFNG, TNF
18positive regulation of T cell differentiationGO:00455829.9IL2, IL2RA
19adaptive immune responseGO:00022509.7CD46, IFNG, IL2
20response to virusGO:00096159.4IFNAR2, IFNG, TNF
21positive regulation of interferon-gamma productionGO:00327299.0HLA-DPB1, IL12RB2, IL2, TNF
22defense response to virusGO:00516078.9IFNAR2, IFNG, IL10RB, STAT1, STAT2
23T cell costimulationGO:00312958.8CD40LG, HLA-DPB1, HLA-DRB1
24inflammatory responseGO:00069548.8CD40LG, IL10RB, IL2RA, TNF
25interferon-gamma-mediated signaling pathwayGO:00603338.6HLA-DPB1, HLA-DRB1, IFNG, IRF2, STAT1
26cell surface receptor signaling pathwayGO:00071668.5IFNAR2, IFNG, IL12RB2, IL2RA
27positive regulation of T cell proliferationGO:00421027.7CD40LG, CD46, HLA-DPB1, IFNG, IL2, IL2RA

Molecular functions related to Mumps according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:00051649.8CD40LG, STAT1, TNF
2cytokine activityGO:00051258.8CD40LG, IFNG, IL2, TNF

Sources for Mumps

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet