Mumps disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Mumps

Sources:
⁹Disease Ontology, ³³MedlinePlus, ⁴CDC, ⁶⁴Wikipedia, ³²MalaCards
See all sources

MedlinePlus:³³ Mumps is an illness caused by the mumps virus. it starts with fever headache muscle aches tiredness loss of appetite after that, the salivary glands under the ears or jaw become swollen and tender. the swelling can be on one or both sides of the face. symptoms last 7 to 10 days. serious complications are rare. you can catch mumps by being with another person who has it. there is no treatment for mumps, but the measles-mumps-rubella (mmr) vaccine can prevent it. before the routine vaccination program in the united states, mumps was a common illness in infants, children and young adults. now it is a rare disease in the u.s. centers for disease control and prevention

MalaCards based summary: Mumps is related to measles and hepatitis, and has symptoms including fever, headache and muscle aches. An important gene associated with Mumps is STAT2 (signal transducer and activator of transcription 2, 113kDa), and among its related pathways are NF-kappaB Signaling and CXCR4-mediated signaling events. The compounds mumps and gliadin have been mentioned in the context of this disorder. Affiliated tissues include salivary gl, salivary gland and testes, and related mouse phenotypes are integument and skeleton.

Disease Ontology:⁹ A viral infectious disease that results in inflammation located in salivary gland, has material basis in mumps virus, which is transmitted by droplet spread of saliva or mucus from the mouth, nose, or throat of an infected person, or transmitted by contaminated fomites. the infection has symptom fever, has symptom headache, has symptom muscle aches, has symptom tiredness, has symptom loss of appetite, has symptom swollen and tender salivary glands under the ears or jaw on one or both sides of the face.

CDC:⁴ Mumps is a contagious disease that is caused by the mumps virus. Mumps typically starts with a few days of fever, headache, muscle aches, tiredness, and loss of appetite, and is followed by swelling of salivary glands. Anyone who is not immune from either previous mumps infection or from vaccination can get mumps. Before the routine vaccination program was introduced in the United States, mumps was a common illness in infants, children and young adults. Because most people have now been vaccinated, mumps has become a rare disease in the United States...more

Wikipedia:⁶⁴ Mumps (epidemic parotitis) is a viral disease of the human species, caused by the mumps virus. Before... more...

Aliases & Classifications for Mumps

Sources:
⁹Disease Ontology, ⁴²NIH Rare Diseases, ¹¹DISEASES, ⁴⁴Novoseek, ³³MedlinePlus, ⁶¹UMLS, ⁵⁶SNOMED-CT, ³⁹NCIt, ³⁴MeSH, ²⁸ICD9CM, ²⁶ICD10
See all sources

Mumps, Aliases & Descriptions:

Name: Mumps ⁹ ⁴² ¹¹ ⁴⁴ ³³ ⁶¹

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases
Anatomical: Oral diseases

ICD10: ²⁶

Certain infectious and parasitic diseases

Other viral diseases

Mumps

Mumps with other complications

Mumps without complication

External Ids:

Disease Ontology⁹ DOID:10264

NCIt³⁹ C29888

MeSH³⁴ D009107

SNOMED-CT⁵⁶ 186652008, 240526004, 36989005 186651001, 154352008, more

ICD9CM²⁸ 072

ICD10²⁶ B26, B26.8, B26.9

UMLS⁶¹ C0026780

Related Diseases for Mumps

Sources:
¹⁸GeneCards, ¹⁹GeneDecks
See all sources

Diseases in the Mumps family:

Congenital Mumps

Diseases related to Mumps via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50) (show all 163)

id	Related Disease	Score	Top Affiliating Genes
1	measles	31.6	IRF1, STAT1, IFNAR2
2	hepatitis	30.8	IFNA2, STAT1
3	influenza	30.6	STAT1, IRF1, NEU1
4	newcastle disease	30.1	NEU1, IRF1
5	herpes simplex	29.9	NEU1, IRF1, STAT1
6	leukemia	29.9	IRF1, IRF2, STAT1, IFNA2
7	asthma	29.8	STAT1, IRF1, NEU1
8	multiple sclerosis	29.8	IRF1, STAT1, IFNAR2
9	hepatitis b	29.7	CFB, IRF1, STAT1, IFNA2, IFNAR2
10	myeloid leukemia	29.5	NEU1, IRF1, STAT2, STAT1
11	rubella	11.1
12	orchitis	10.7
13	meningitis	10.7
14	aseptic meningitis	10.6
15	parotitis	10.6
16	meningoencephalitis	10.4
17	encephalitis	10.4
18	tetanus	10.4
19	endocardial fibroelastosis	10.3
20	epididymo-orchitis	10.3
21	haemophilus influenzae	10.3
22	diphtheria	10.3
23	pertussis	10.3
24	poliomyelitis	10.3
25	myelitis	10.3
26	hepatitis a	10.3
27	pancreatitis	10.3
28	transverse myelitis	10.3
29	epididymitis	10.3
30	hydrocephalus	10.2
31	sialadenitis	10.2
32	chickenpox	10.2
33	labyrinthitis	10.2
34	purpura	10.2
35	congenital mumps	10.2
36	congenital rubella	10.2
37	viral hepatitis	10.1	IFNA2, STAT1
38	fanconi's anemia	10.1	IRF1, STAT1
39	cutaneous t cell lymphoma	10.1	STAT1, IFNA2
40	arthritis	10.1
41	acute pancreatitis	10.1
42	infertility	10.1
43	myocarditis	10.1
44	febrile seizures	10.1
45	endotheliitis	10.1
46	hemolytic anemia	10.1	NEU1, IFNA2
47	carcinoid syndrome	10.1	IFNA2, IRF2, IRF1
48	fibrosarcoma	10.1	STAT1, STAT2, IRF1
49	peripheral primitive neuroectodermal tumor	10.1	IRF1, STAT1
50	eosinophilia	10.1	IFNA2, STAT1

Graphical network of the top 20 diseases related to Mumps:

Symptoms for Mumps

Sources:
⁹Disease Ontology
See all sources

Symptoms:

⁹

fever
headache
muscle aches

tiredness
loss of appetite
swollen

Drugs & Therapeutics for Mumps

Sources:
⁴¹NIH Clinical Center, ⁶ClinicalTrials, ⁶¹UMLS, ⁴⁰NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Mumps

Search NIH Clinical Center for Mumps

Genetic Tests for Mumps

Anatomical Context for Mumps

Sources:
³²MalaCards, ¹⁵FMA
See all sources

MalaCards organs/tissues related to Mumps:

³²

Salivary gland, Testes, B cells, Thyroid, Skin, T cells, Endothelial, Bone marrow, Bone, Brain, Myeloid

FMA organs/tissues related to Mumps:

¹⁵

Salivary gl

Animal Models for Mumps or affiliated genes

Sources:
³⁶MGI
See all sources

MGI Mouse Phenotypes related to Mumps:

³⁶

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	integument phenotype	MP:0010771	8.5	STAT1, IRF2, IRF1, NEU1
2	skeleton phenotype	MP:0005390	7.8	CFB, NEU1, IRF1, STAT1
3	hematopoietic system phenotype	MP:0005397	7.7	NEU1, IRF1, IRF2, STAT2, STAT1, IFNAR2
4	mortality/aging	MP:0010768	7.6	NEU1, IRF1, IRF2, STAT2, STAT1, IFNAR2
5	immune system phenotype	MP:0005387	6.9	IFNAR2, CFB, NEU1, IRF1, IRF2, STAT2

Publications for Mumps

Sources:
⁵¹PubMed
See all sources

Articles related to Mumps:

(show top 50) (show all 680)

id	Title	Authors	Year
1	Mumps outbreak in the Federation of Bosnia and Herzegovina with large cohorts of susceptibles and genetically diverse strains of genotype G, Bosnia and Herzegovina, December 2010 to September 2012. (25166347)	Hukic M.... Hubschen J.M.	2014
2	Increased levels of cytokines in cerebrospinal fluid of children with aseptic meningitis caused by mumps virus and echovirus 30. (24313836)	Sulik A.... Oldak E.	2014
3	Mumps vaccine effectiveness and risk factors for disease in households during an outbreak in New York City. (24252695)	Livingston K.A.... Zimmerman C.M.	2014
4	Decline of varicella vaccination in German surveillance regions after recommendation of separate first-dose vaccination for varicella and measles-mumps-rubella. (24412300)	Streng A.... Liese J.G.	2014
5	Seroprevalence survey on measles, mumps, rubella and varicella antibodies in healthcare workers in Japan: sex, age, occupational-related differences and vaccine efficacy. (23574767)	Kumakura S.... Hirose M.	2014
6	Risk Factors for Transmission of Mumps in a Highly Vaccinated Population in Orange County, NY, 2009-2010. (23995590)	Kutty P.K.... Wallace G.	2014
7	Investigation of an outbreak of hypersensitivity-type reactions during the 2004 national measles-mumps-rubella vaccination campaign in Brazil. (23246259)	Freitas D.R.... Hatch D.L.	2013
8	Influence of Vaccination dose and clinico-demographical factors on antibody titers against measles, rubella, mumps, and varicella-zoster viruses among university students in Japan. (24270137)	Takeuchi J.... Hiraide A.	2013
9	Outbreak-related mumps vaccine effectiveness among a cohort of children and of young adults in Germany 2011. (24091837)	Takla A.... Koch J.	2013
10	Waning of maternal antibodies against measles, mumps, rubella, and varicella in communities with contrasting vaccination coverage. (23661802)	Waaijenborg S.... Wallinga J.	2013
11	Characterisation of mumps virus genotype C among patients with mumps in India. (23883719)	Jeevan M.... Thangam M.	2013
12	Spermiogram part of population with the manifest orchitis during an ongoing epidemic of mumps. (22937687)	Gazibera B.... Muratovic P.	2012
13	Establishment of a standard seed lot system of an Iranian Mumps virus strain; RS-12, for mass production of mumps and MMR vaccines. (23115712)	Shahkarami M.K.... Mohammadi A.	2012
14	Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations? (22687578)	Eriksen J.... Pebody R.	2012
15	Acupuncture for mumps in children. (22972121)	He J.... Jiang H.	2012
16	Pityriasis lichenoides et varioliformis acuta: a rare association with the measles, mumps and rubella vaccine. (23157791)	Gunatheesan S.... Moosa Y.	2012
17	Seroprevalence of measles, mumps, rubella, varicella-zoster and hepatitis A-C in Emirati medical students. (23217121)	Sheek-Hussein M.... Souid A.K.	2012
18	Air-coupled MUMPs capacitive micromachined ultrasonic transducers with resonant cavities. (22099252)	Octavio Manzanares A.... Montero de Espinosa F.	2012
19	Mumps exposure of a health care provider working in a neonatal intensive care unit leads to a hospital-wide effort that prevented an outbreak. (21641085)	Gilroy S.A.... Stahl R.	2011
20	Mumps virus encephalitis with symmetric claustrum lesions. (21659481)	Ishii K.... Tamaoka A.	2011
21	Vaccines for measles, mumps, rubella, varicella, and herpes zoster: immunization guidelines for adults. (22086887)	Hendriksz T.... Foy J.E.	2011
22	A 176 amino acid polypeptide derived from the mumps virus HN ectodomain shows immunological and biological properties similar to the HN protein. (20727167)	Herrera E.... BarrA^n B.	2010
23	Lower long-term immunogenicity of mumps component after MMR vaccine. (20975455)	De Laval F.... Simon F.	2010
24	Measles-mumps-rubella-varicella combination vaccine and the risk of febrile seizures. (20587679)	Klein N.P.... Weintraub E.	2010
25	Closer look at autism and the measles-mumps-rubella vaccine. (21071320)	Hensley E.... Briars L.	2010
26	Mumps vaccine effectiveness in highly immunized populations. (20226249)	DomA-nguez A.... Jansa J.M.	2010
27	Role of laboratory in rapid diagnosis of atypical mumps. (20563452)	Vandana K.E.... Bairy I.	2010
28	Molecular differences between two Jeryl Lynn mumps virus vaccine component strains, JL5 and JL2. (19656963)	Chambers P.... Duprex W.P.	2009
29	An office-based prospective study of deafness in mumps. (19209100)	Hashimoto H.... Kinumaki H.	2009
30	Immunogenicity and safety of measles-mumps-rubella-varicella (MMRV) vaccine followed by one dose of varicella vaccine in children aged 15 months-2 years or 2-6 years primed with measles-mumps-rubella (MMR) vaccine. (19007835)	Gillet Y.... Willems P.	2009
31	Mumps virus Enders strain is sensitive to interferon (IFN) despite encoding a functional IFN antagonist. (19625458)	Young D.F.... Randall R.E.	2009
32	Mumps: not an innocent bystander in solid organ transplantation. (19563333)	Baas M.C.... Bemelman F.J.	2009
33	Immunogenicity and safety of concomitant administration of a measles, mumps and rubella vaccine (M-M-RvaxPro) and a varicella vaccine (VARIVAX) by intramuscular or subcutaneous routes at separate injection sites: a randomised clinical trial. (19366435)	Gillet Y.... Fiquet A.	2009
34	Mumps outbreak on the island of Anglesey, North Wales, December 2008-January 2009. (19215718)	Roberts C.... Hart J.	2009
35	Differential mechanisms of complement-mediated neutralization of the closely related paramyxoviruses simian virus 5 and mumps virus. (18440578)	Johnson J.B.... Parks G.D.	2008
36	Detection of mumps virus RNA by real-time one-step reverse transcriptase PCR using the LightCycler platform. (18945836)	Leblanc J.J.... Hatchette T.F.	2008
37	The role of air travel in the spread of mumps. (18831704)	Marienau K.J.... Redd S.	2008
38	Updated recommendations for isolation of persons with mumps. (18846033)		2008
39	Mumps outbreak in a highly vaccinated school population: assessment of secondary vaccine failure using IgG avidity measurements. (17498856)	Park D.W.... Kim M.J.	2007
40	Assessing participation bias in a population-based study of measles-mumps-rubella vaccine immunity in children and adolescents aged 12-18. (17564596)	St Sauver J.L.... Poland G.A.	2007
41	Comparison of the safety and immunogenicity of a refrigerator-stable versus a frozen formulation of ProQuad (measles, mumps, rubella, and varicella virus vaccine live). (17502347)	Bernstein H.H.... Kuter B.J.	2007
42	Human leukocyte antigen class II alleles and rubella-specific humoral and cell-mediated immunity following measles-mumps-rubella-II vaccination. (15655774)	Ovsyannikova I.G.... Poland G.A.	2005
43	Assessment of humoral immunity to poliomyelitis, tetanus, hepatitis B, measles, rubella, and mumps in children after chemotherapy. (15717298)	Fioredda F.... Castagnola E.	2005
44	Mumps epididymo-orchitis with prolonged detection of virus in semen and the development of anti-sperm antibodies. (15042662)	Jalal H.... Brink N.	2004
45	The risk of aseptic meningitis associated with the Leningrad-Zagreb mumps vaccine strain following mass vaccination with measles-mumps-rubella vaccine, Rio Grande do Sul, Brazil, 1997. (12435771)	da Silveira C.M.... Prevots D.R.	2002
46	Previous exposure to measles, mumps, and rubella--but not vaccination during adolescence--correlates to the prevalence of pancreatic and thyroid autoantibodies. (10390298)	Lindberg B.... Ivarsson S.A.	1999
47	Systemic alpha-interferon therapy: a possible method for prevention of testicular atrophy and permanent sterility in patients with bilateral mumps orchitis]. (1926670)	Erpenbach K.... Derschum W.	1991
48	Mumps pancreatitis without parotitis. (4692679)	Naficy K.... Ghadimi H.	1973
49	LEUKEMOID REACTION TO MUMPS VIRUS. (14160741)	Garcia R.... RASCH C.A.	1964
50	Mumps meningoencephalitis with and without parotitis. (18147966)	KILHAM L.	1949

Genes related to Mumps

Sources:
¹⁸GeneCards, ¹antibodies-online, ⁴⁵Novus Biologicals
See all sources

Genes related to Mumps:

- Elite gene

id	Symbol	Description	Score	Implication
1	STAT2	signal transducer and activator of transcription 2, 113kDa	21.21	GeneCards inferred via : Publications, Drugs & Compounds, Disorders (show sections)
2	IRF1	interferon regulatory factor 1	18.71	GeneCards inferred via : Publications, Disorders (show sections)
3	IRF2	interferon regulatory factor 2	16.21	GeneCards inferred via : Publications, Disorders (show sections)
4	IFNA2	interferon, alpha 2	13.71	GeneCards inferred via : Publications, Disorders (show sections)
5	STAT1	signal transducer and activator of transcription 1, 91kDa	11.21	GeneCards inferred via : Publications, Drugs & Compounds, Disorders (show sections)
6	NEU1	sialidase 1 (lysosomal sialidase)	8.71	GeneCards inferred via : Disorders (show sections)
7	CFB	complement factor B	6.15	GeneCards inferred via : Publications (show sections)
8	IFNAR2	interferon (alpha, beta and omega) receptor 2	3.65	GeneCards inferred via : Publications (show sections)

Products for genes related to Mumps disease:

id	Company	Proteins	Lysates	Antibodies	Kits and Assays
1	Antibodies-online	8	-	8	8
2	Novus Biologicals	8	8	8	-

Variations for Mumps

Expression for genes affiliated with Mumps

Sources:
²BioGPS, ¹⁶Gene Expression Omnibus DataSets
See all sources

Expression patterns in normal tissues for genes affiliated with Mumps

Search GEO for disease gene expression data for Mumps.

Pathways for genes affiliated with Mumps

Sources:
⁴⁹PathCards, ⁵Cell Signaling Technology, ³⁷NCBI BioSystems Database, ⁵³R&D Systems, ⁵²QIAGEN, ⁵⁹Thomson Reuters, ⁵⁴Reactome, ³⁰KEGG
See all sources

Pathways related to Mumps according to GeneCards/GeneDecks:

(show all 26)

id	Super pathways (with members indented)	Score	Top Affiliating Genes
1	NF-kappaB Signaling⁵	9.7	IRF2, IRF1
2	CXCR4-mediated signaling events³⁷	9.6	STAT1, STAT2
3	Th1 Differentiation⁵³ Show member pathways IL27-mediated signaling events³⁷	9.6	STAT2, STAT1
4	CNTF Signaling⁵² Show member pathways Nur77-Induced AICD in Macrophage⁵² IL-3 Pathway⁵² OSM Pathway⁵² FLT3 Signaling⁵²	9.6	STAT1, STAT2
5	Jak/Stat Pathway⁵ Show member pathways Development Thrombopoetin signaling via JAK STAT pathway⁵⁹	9.6	STAT2, STAT1
6	Immune response Bacterial infections in normal airways⁵⁹ Show member pathways Transcription NF kB signaling pathway⁵⁹ Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response⁵⁹ Bacterial infections in CF airways⁵⁹ IL 1 beta dependent CFTR expression⁵⁹	9.6	STAT1, IRF1
7	Toll Comparative Pathway⁵² Show member pathways Immune response MIF in innate immunity response⁵⁹ iNOS Signaling⁵² TLR-TRIF Pathway⁵² IL-1 Pathway⁵²	9.6	STAT1, IRF1
8	IL6-mediated signaling events³⁷	9.6	IRF1, STAT1
9	Glucocorticoid receptor regulatory network³⁷	9.6	IRF1, STAT1
10	Regulation of Telomerase³⁷	9.6	IFNAR2, IRF1
11	Hemostasis⁵⁴ Show member pathways Platelet activation, signaling and aggregation⁵⁴	9.2	IFNA2, IRF1, IRF2
12	Factors involved in megakaryocyte development and platelet production⁵⁴	9.2	IRF2, IFNA2, IRF1
13	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways⁵⁴ Show member pathways RIG-I-like receptor signaling pathway³⁰ TRAF6 mediated IRF7 activation⁵⁴ TRAF3-dependent IRF activation pathway⁵⁴ NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10⁵⁴ Negative regulators of RIG-I/MDA5 signaling⁵⁴	9.2	IRF1, IRF2, IFNA2
14	Immune response IFN gamma signaling pathway⁵⁹ Show member pathways IFN-gamma pathway³⁷	9.2	STAT1, STAT2, IRF1
15	NOD-like Receptor Signaling Pathways⁵³ Show member pathways Toll-Like receptor Signaling Pathways⁵³ Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways⁵³ Inflammasome Activation Pathways⁵³ Mucin expression in CF via TLRs, EGFR signaling pathways⁵⁹ IL-1 Family Signaling Pathways⁵³ Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways⁵⁹ Immune response IL 1 signaling pathway⁵⁹	9.1	IFNA2, STAT1, IRF1
16	Interferon type I³⁷	9.1	STAT1, STAT2, IFNAR2
17	Osteoclast differentiation³⁰	9.1	IFNAR2, STAT1, STAT2
18	Interferon Pathway⁵²	8.6	STAT1, IFNA2, STAT2, IFNAR2
19	Jak-STAT signaling pathway³⁰ Show member pathways Type III interferon signaling³⁷	8.6	STAT1, STAT2, IFNAR2, IFNA2
20	Toll-like receptor signaling pathway³⁰ Show member pathways Chagas disease (American trypanosomiasis)³⁰ Toll-like receptor signaling pathway³⁷ Regulation of toll-like receptor signaling pathway³⁷ Hepatitis B³⁰	8.6	IFNA2, STAT1, STAT2, IFNAR2
21	Influenza A³⁰ Show member pathways Measles³⁰ Herpes simplex infection³⁰	8.6	IFNAR2, STAT2, STAT1, IFNA2
22	TGF-Beta Pathway⁵² Show member pathways SOCS Pathway⁵² JAK-STAT Pathway⁵² Regulation of eIF4 and p70S6K⁵² JNK Pathway⁵² MAPK Family Pathway⁵²	8.6	IFNAR2, STAT2, STAT1, IFNA2
23	Type II interferon signaling (IFNG)³⁷	8.4	IRF1, STAT2, STAT1, IFNA2, IRF2
24	Hepatitis C³⁰	8.3	IFNAR2, IFNA2, STAT1, IRF1, STAT2
25	Interferon Signaling⁵⁴ Show member pathways ISG15 antiviral mechanism⁵⁴ Cytokine Signaling in Immune system⁵⁴ Regulation of IFNG signaling⁵⁴ Interferon gamma signaling⁵⁴ Antiviral mechanism by IFN-stimulated genes⁵⁴	7.8	IRF1, IFNAR2, STAT2, IRF2, STAT1, IFNA2
26	Immune response IFN alpha beta signaling pathway⁵⁹ Show member pathways Regulation of IFNA signaling⁵⁴ Interferon alpha/beta signaling⁵⁴	7.8	IRF1, IFNA2, IFNAR2, STAT2, STAT1, IRF2

Compounds for genes affiliated with Mumps

Sources:
⁴⁴Novoseek, ¹²DrugBank, ⁶⁰Tocris Bioscience, ²⁹IUPHAR, ⁵⁰PharmGKB, ²⁵HMDB
See all sources

Compounds related to Mumps according to GeneCards/GeneDecks:

(show all 30)

id	Compound	Score	Top Affiliating Genes
1	mumps⁴⁴	10.0	STAT1, STAT2
2	gliadin⁴⁴	9.9	IRF1, STAT1
3	indoleamine⁴⁴	9.9	STAT1, IRF1
4	inosine monophosphate⁴⁴	9.8	IRF1, STAT1
5	deferoxamine⁴⁴ ¹²	10.8	STAT1, IRF1
6	imiquimod⁴⁴ ⁶⁰ ²⁹ ¹²	12.8	IFNA2, STAT1
7	polyinosinic-polycytidylic acid⁴⁴	9.8	STAT1, IRF1
8	amantadine⁴⁴ ¹²	10.7	IFNA2, NEU1
9	suberoylanilide hydroxamic acid⁴⁴	9.7	IRF1, STAT1
10	levamisole⁴⁴ ¹²	10.7	NEU1, IFNA2
11	acyclovir⁴⁴ ¹²	10.7	IFNA2, NEU1
12	poly(i-c)⁴⁴	9.7	STAT1, IRF1
13	con a⁴⁴	9.6	IFNA2, NEU1
14	vanadate⁴⁴	9.6	STAT1, STAT2
15	retinoid⁴⁴	9.4	IRF1, STAT1, IFNA2
16	etoposide⁴⁴ ⁵⁰ ⁶⁰ ¹²	12.4	IRF1, STAT1, IFNA2
17	galactose⁴⁴	9.4	IFNA2, NEU1
18	zidovudine⁴⁴ ⁵⁰ ¹²	11.3	NEU1, IFNA2
19	cellulose acetate⁴⁴	9.3	NEU1, CFB
20	ribavirin⁴⁴ ⁵⁰ ¹²	11.2	NEU1, STAT1, IFNA2
21	polyethylene glycol⁴⁴	9.1	IFNA2, NEU1
22	agarose⁴⁴	8.9	CFB, NEU1, IFNA2
23	cycloheximide⁴⁴	8.9	STAT1, IRF2, IRF1, NEU1
24	estrogen⁴⁴	8.8	NEU1, IRF1, STAT1, IFNA2
25	lipid⁴⁴	8.7	IRF1, STAT1, IFNA2, IFNAR2
26	ifn-alpha⁴⁴	8.6	IRF1, STAT2, STAT1, IFNA2, IFNAR2
27	2,5-oligoadenylate⁴⁴	8.2	IFNAR2, IFNA2, STAT1, STAT2, IRF2, IRF1
28	tyrosine⁴⁴	8.2	IRF1, IRF2, STAT2, STAT1, IFNA2, IFNAR2
29	serine⁴⁴	7.8	CFB, NEU1, IRF1, IRF2, STAT2, STAT1
30	retinoic acid⁴⁴ ²⁵	8.6	NEU1, IRF1, IRF2, STAT2, STAT1, IFNA2

GO Terms for genes affiliated with Mumps

Sources:
¹⁷Gene Ontology
See all sources

Cellular components related to Mumps according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	nuclear chromatin	GO:000790	9.6	STAT1, IRF1
2	nucleoplasm	GO:005654	8.5	STAT1, STAT2, IRF2, IRF1

Biological processes related to Mumps according to GeneCards/GeneDecks:

(show all 10)

id	Name	GO ID	Score	Top Affiliating Genes
1	cellular response to interferon-beta	GO:035458	9.6	IRF1, STAT1
2	interferon-gamma-mediated signaling pathway	GO:060333	9.2	STAT1, IRF2, IRF1
3	JAK-STAT cascade	GO:007259	9.2	IFNAR2, STAT1, STAT2
4	apoptotic process	GO:006915	9.1	IFNA2, STAT1, IRF1
5	regulation of transcription from RNA polymerase II promoter	GO:006357	9.0	IFNAR2, STAT1, STAT2
6	blood coagulation	GO:007596	8.9	IRF1, IRF2, IFNA2
7	defense response to virus	GO:051607	8.9	IRF1, STAT2, STAT1, IFNA2
8	regulation of type I interferon-mediated signaling pathway	GO:060338	8.8	IFNAR2, IFNA2, STAT1, STAT2
9	type I interferon signaling pathway	GO:060337	8.1	IFNAR2, IFNA2, STAT1, STAT2, IRF2, IRF1
10	cytokine-mediated signaling pathway	GO:019221	8.0	IRF1, IRF2, STAT2, STAT1, IFNA2, IFNAR2

Molecular functions related to Mumps according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:000978	9.6	STAT1, IRF1
2	sequence-specific DNA binding transcription factor activity	GO:003700	8.5	STAT1, STAT2, IRF2, IRF1

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³⁷NCBI BioSystems Database

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⁴¹NIH Clinical Center

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⁵⁷SNOMED-CT via Orphanet

⁵⁸The Human Phenotype Ontology

⁵⁹Thomson Reuters

⁶⁰Tocris Bioscience

⁶¹UMLS

⁶²UMLS via Orphanet

⁶³UniProtKB/Swiss-Prot

⁶⁴Wikipedia

MUMPS MCID: MMP001 MIFTS: 59	Mumps (MUMPS) malady Rare diseases, Infectious diseases, Oral diseases categories
6 symptoms, 8 genes, 12 tissues, 163 related diseases, clinical trials Download this MalaCard Expand all tables

Mumps (MUMPS) malady