MCID: MRR003
MIFTS: 39

Murray Valley Encephalitis malady

Categories: Infectious diseases, Neuronal diseases

Aliases & Classifications for Murray Valley Encephalitis

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Aliases & Descriptions for Murray Valley Encephalitis:

Name: Murray Valley Encephalitis 11 13 67
Australian Encephalitis 11
 
Australian X Disease 11

Classifications:



External Ids:

Disease Ontology11 DOID:10842
ICD1029 A83.4
SNOMED-CT61 66454007
ICD9CM31 062.4

Summaries for Murray Valley Encephalitis

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Disease Ontology:11 A viral infectious disease that results in inflammation located in brain, has material basis in Murray Valley encephalitis virus, which is transmitted by Culex annulirostris mosquitoes. The infection has symptom fever, has symptom headache, has symptom nausea, has symptom vomiting, has symptom drowsiness, has symptom confusion, has symptom fitting, and has symptom weakness.

MalaCards based summary: Murray Valley Encephalitis, also known as australian encephalitis, is related to japanese encephalitis and encephalitis, and has symptoms including fever, headache and nausea. An important gene associated with Murray Valley Encephalitis is RAF1 (Raf-1 Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways are CD209 (DC-SIGN) signaling and G-protein signaling_K-RAS regulation pathway. Affiliated tissues include brain, brain and testes, and related mouse phenotypes are neoplasm and integument.

Related Diseases for Murray Valley Encephalitis

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Diseases related to Murray Valley Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idRelated DiseaseScoreTop Affiliating Genes
1japanese encephalitis25.4CD40LG, DICER1, DROSHA, ERVW-1, IL2, KRAS
2encephalitis11.1
3pterygium colli mental retardation digital anomalies10.6KRAS, RAF1
4rad51c-related fanconi anemia10.6KRAS, RAF1
5ainhum10.5CD40LG, RAF1
6brachial plexus neuritis10.5KRAS, RAF1
7bladder benign neoplasm10.5KRAS, RAF1
8bone cancer10.4CD40LG, MYOM2
9rete ovarii cystadenoma10.4CD40LG, MYOM2
10calcinosis10.4CD40LG, MYOM2
11classic pulmonary blastoma10.4DICER1, KRAS
12radioulnar synostosis10.4KRAS, RAF1
13ureter leiomyoma10.4CD40LG, MYOM2
14infertility10.3CD40LG, MYOM2
15smoldering myeloma10.3CD40LG, MYOM2
16temporal arteritis10.3CD40LG, MYOM2
17non-secretory myeloma10.3CD40LG, MYOM2
18dentin dysplasia10.3CD40LG, KRAS, RAF1
19secretory diarrhea10.3CD40LG, STAB2
20brucella abortus brucellosis10.3CD40LG, IL2
21phlyctenulosis10.3CD40LG, MYOM2
22generalized atherosclerosis10.3CD40LG, MYOM2
23agammaglobulinemia, microcephaly, and severe dermatitis10.3CD40LG, IL2
24strawberry gallbladder10.3CD40LG, IL2
25maligant granulosa cell tumor of ovary10.2IL2, MYOM2
26solitary osseous plasmacytoma10.2IL2, MYOM2
27west nile virus10.2
28neurofibroma of the esophagus10.1IL2, MYOM2
29huntington disease-like 110.1PRNP, THY1
30pneumonic tularemia10.1CD40LG, IL2
31epididymis adenomatoid tumor10.1CD40LG, MYOM2
32st. louis encephalitis10.1
33early congenital syphilis10.1CD40LG, IL2, KRAS
34foodborne botulism10.1CD40LG, MYOM2
35ovarian endometrioid malignant adenofibroma10.1CD40LG, IL2
36night blindness10.0CD40LG, ERVW-1
37lacrimal system cancer10.0CD40LG, IL2, MYOM2
38renovascular hypertension10.0CD40LG, IL2, MYOM2
39bacteriuria10.0CD40LG, IL2, MYOM2
40heart lymphoma10.0CD40LG, MYOM2
41hemolytic anemia10.0CD40LG, IL2, MYOM2
42organ system benign neoplasm10.0CD40LG, IL2, MYOM2
43male urethral cancer10.0CD40LG, IL2
44louping ill9.9
45poliomyelitis9.9
46herpes simplex9.9
47yellow fever9.9
48herpes simplex encephalitis9.9
49gemistocytic astrocytoma9.9CD40LG, IL2, PRNP
50sweat gland cancer9.9CD40LG, ERVW-1

Graphical network of the top 20 diseases related to Murray Valley Encephalitis:



Diseases related to murray valley encephalitis

Symptoms for Murray Valley Encephalitis

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Symptoms:

 11 (show all 8)
  • fever
  • headache
  • nausea
  • vomiting
  • drowsiness
  • confusion
  • fitting
  • weakness

Drugs & Therapeutics for Murray Valley Encephalitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Murray Valley Encephalitis

Genetic Tests for Murray Valley Encephalitis

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Anatomical Context for Murray Valley Encephalitis

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MalaCards organs/tissues related to Murray Valley Encephalitis:

35
Brain, Testes, Neutrophil, B cells, Kidney

FMA organs/tissues related to Murray Valley Encephalitis:

17
Brain

Animal Models for Murray Valley Encephalitis or affiliated genes

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MGI Mouse Phenotypes related to Murray Valley Encephalitis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.5DICER1, IL2, KRAS, RAF1, STAB2
2MP:00107719.2CD40LG, DICER1, DROSHA, KRAS, PRNP, RAF1
3MP:00053709.2DICER1, DROSHA, IL2, KRAS, RAF1, STAB2
4MP:00053858.9CD40LG, DICER1, DROSHA, IL2, KRAS, RAF1
5MP:00053798.7CD40LG, DICER1, DROSHA, IL2, KRAS, PRNP
6MP:00028738.7DICER1, DROSHA, KRAS, PRNP, RAF1, STAB2
7MP:00053887.9DICER1, DROSHA, IL2, KRAS, RAF1, STAB2

Publications for Murray Valley Encephalitis

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Articles related to Murray Valley Encephalitis:

(show top 50)    (show all 176)
idTitleAuthorsYear
1
Phylogeny of Murray Valley encephalitis virus in Australia and Papua New Guinea. (27086158)
2016
2
A Bayesian Belief Network for Murray Valley encephalitis virus risk assessment in Western Australia. (26823368)
2016
3
The Molecular Epidemiology and Evolution of Murray Valley Encephalitis Virus: Recent Emergence of Distinct Sub-lineages of the Dominant Genotype 1. (26600318)
2015
4
Murray Valley encephalitis: a review of clinical features, diagnosis and treatment. (22432670)
2012
5
Solid-phase synthesis and screening of a library of C-terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease. (22991186)
2012
6
Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. (22379060)
2012
7
Biochemical characterisation of Murray Valley encephalitis virus proteinase. (20621842)
2010
8
Live chimeric and inactivated Japanese encephalitis virus vaccines differ in their cross-protective values against Murray Valley encephalitis virus. (19109382)
2009
9
Murray Valley encephalitis in an adult traveller complicated by long-term flaccid paralysis: case report and review of the literature. (17161855)
2007
10
Genetic and phenotypic differences between isolates of Murray Valley encephalitis virus in Western Australia, 1972-2003. (17393295)
2007
11
Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. (17622627)
2007
12
Antibody-dependent enhancement of Murray Valley encephalitis virus virulence in mice. (12810865)
2003
13
Mechanism of virulence attenuation of glycosaminoglycan-binding variants of Japanese encephalitis virus and Murray Valley encephalitis virus. (11967307)
2002
14
Murray Valley encephalitis virus surveillance and control initiatives in Australia. National Arbovirus Advisory Committee of the Communicable Diseases Network Australia. (11432524)
2001
15
Attenuation of Murray Valley encephalitis virus by site-directed mutagenesis of the hinge and putative receptor-binding regions of the envelope protein. (11462041)
2001
16
Determination of the intramolecular disulfide bond arrangement and biochemical identification of the glycosylation sites of the nonstructural protein NS1 of Murray Valley encephalitis virus. (11514736)
2001
17
Characterization of infectious Murray Valley encephalitis virus derived from a stably cloned genome-length cDNA. (10567642)
1999
18
DNA-based and alphavirus-vectored immunisation with prM and E proteins elicits long-lived and protective immunity against the flavivirus, Murray Valley encephalitis virus. (9770429)
1998
19
Two possible mechanisms for survival and initiation of Murray Valley encephalitis virus activity in the Kimberley region of Western Australia. (7625542)
1995
20
Murray valley encephalitis virus envelope protein antigenic variants with altered hemagglutination properties and reduced neuroinvasiveness in mice. (7645203)
1995
21
A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes. (1383567)
1992
22
Persistent infection of Vero cells by the flavivirus Murray Valley encephalitis virus. (1848592)
1991
23
Sequence of the 3' half of the Murray Valley encephalitis virus genome and mapping of the nonstructural proteins NS1, NS3, and NS5. (1702914)
1990
24
Synthetic peptides derived from the deduced amino acid sequence of the E-glycoprotein of Murray Valley encephalitis virus elicit antiviral antibody. (2472704)
1989
25
The vector competence of Culex annulirostris, Aedes sagax and Aedes alboannulatus for Murray Valley encephalitis virus at different temperatures. (2562418)
1989
26
Murray Valley encephalitis virus field strains from Australia and Papua New Guinea: studies on the sequence of the major envelope protein gene and virulence for mice. (2838962)
1988
27
Type-specific monoclonal antibodies produced to proteins of Murray Valley encephalitis virus. (2453454)
1988
28
The experimental infection of horses with Murray Valley encephalitis and Ross River viruses. (3038067)
1987
29
A method for predicting Murray Valley encephalitis in southeast Australia using the Southern Oscillation. (3036054)
1986
30
Comparison of proteins specified by Murray Valley encephalitis, West Nile, Japanese encephalitis and St. Louis encephalitis viruses. (3579743)
1986
31
Partial nucleotide sequence of the Murray Valley encephalitis virus genome. Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins. (3009829)
1986
32
Serological evidence of inter-epidemic infection of feral pigs in New South Wales with Murray Valley encephalitis virus. (1016127)
1976
33
Isolation of Murray Valley encephalitis virus from the brains of three patients with encephalitis. (994931)
1976
34
Murray Valley encephalitis in Australia, 1974: antibody response in cases and community. (1071876)
1976
35
The proteins of Murray Valley encephalitis virus. (806663)
1975
36
Letter: Murray Valley encephalitis virus in Eastern Australia, 1971. (4758166)
1973
37
Intratypic antigenic variation among strains of the group B arboviruses Murray Valley encephalitis and Kunjin. (4997354)
1971
38
Studies of the morphology of Murray Valley encephalitis and Japanese encephalitis viruses growing in cultured mosquito cells. (5651024)
1968
39
Antibody to Murray valley encephalitis and louping-ill viruses in Austrlia and Pauua-New Guinea. (13683282)
1961
40
Murray Valley encephalitis in Papua and New Guinea. II. Serological survey, 1956-1957. (13683283)
1960
41
Some aspects of the reaction between crude Murray Valley encephalitis (MVE) virus and deoxycholate. (13669348)
1959
42
The psychological sequelae to Murray Valley encephalitis. (13492797)
1957
43
Challenge of hamsters with Japanese B, St. Louis and Murray Valley encephalitis viruses after immunization by West Nile infection plus specific vaccine. (13481371)
1957
44
Serological group reactions of Murray Valley encephalitis virus. (13328731)
1956
45
Between Australian x-disease and the virus of Murray Valley encephalitis. (13164666)
1954
46
Murray Valley encephalitis; the contrasting epidemiological picture in 1951 and 1952. (13054045)
1953
47
Murray Valley encephalitis; clinical aspects. (14909903)
1952
48
Murray Valley encephalitis; pathological aspects. (14909904)
1952
49
Murray Valley encephalitis infection in the laboratory mouse. I. Influence of age on susceptibility to infection. (12997453)
1952
50
A fatal case of Murray Valley encephalitis occurring at Narrabri in New South Wales. (13001576)
1952

Variations for Murray Valley Encephalitis

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Expression for genes affiliated with Murray Valley Encephalitis

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Search GEO for disease gene expression data for Murray Valley Encephalitis.

Pathways for genes affiliated with Murray Valley Encephalitis

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GO Terms for genes affiliated with Murray Valley Encephalitis

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Biological processes related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of T cell receptor signaling pathwayGO:005086010.0PRNP, THY1
2pre-miRNA processingGO:00310549.8DICER1, DROSHA
3positive regulation of protein phosphorylationGO:00019349.7IL2, KRAS, RAF1
4production of siRNA involved in RNA interferenceGO:00304229.5DICER1, DROSHA
5negative regulation of apoptotic processGO:00430668.8CD40LG, IL2, PRNP, RAF1

Molecular functions related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ribonuclease III activityGO:00045259.8DICER1, DROSHA
2endoribonuclease activityGO:00045219.5DICER1, DROSHA

Sources for Murray Valley Encephalitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet