MCID: MRR003
MIFTS: 39

Murray Valley Encephalitis malady

Categories: Infectious diseases

Aliases & Classifications for Murray Valley Encephalitis

Aliases & Descriptions for Murray Valley Encephalitis:

Name: Murray Valley Encephalitis 12 14 69
Australian Encephalitis 12
Australian X Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10842
ICD10 33 A83.4
ICD9CM 35 062.4
SNOMED-CT 64 66454007
UMLS 69 C0153066

Summaries for Murray Valley Encephalitis

Disease Ontology : 12 A viral infectious disease that results_in inflammation located in brain, has material basis in Murray Valley encephalitis virus, which is transmitted_by Culex annulirostris mosquitoes. The infection has symptom fever, has symptom headache, has symptom nausea, has symptom vomiting, has symptom drowsiness, has symptom confusion, has symptom fitting, and has symptom weakness.

MalaCards based summary : Murray Valley Encephalitis, also known as australian encephalitis, is related to st. louis encephalitis and encephalitis, and has symptoms including fever, headache and nausea. An important gene associated with Murray Valley Encephalitis is RAF1 (Raf-1 Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways/superpathways are Proteoglycans in cancer and IL-2 Signaling Pathway. Affiliated tissues include brain, testes and neutrophil, and related phenotypes are cardiovascular system and endocrine/exocrine gland

Related Diseases for Murray Valley Encephalitis

Diseases related to Murray Valley Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
id Related Disease Score Top Affiliating Genes
1 st. louis encephalitis 27.8 CD40LG DICER1 DROSHA ERVW-1 IL2 KRAS
2 encephalitis 11.1
3 japanese encephalitis 10.4
4 pseudomonas stutzeri infections 10.3 KRAS RAF1
5 erysipelas 10.3 CD40LG RAF1
6 rdh12-related leber congenital amaurosis 10.3 KRAS RAF1
7 relapsing-remitting multiple sclerosis 10.3 CD40LG STAB2
8 syndactyly-polydactyly-earlobe syndrome 10.2 KRAS RAF1
9 jaw cancer 10.2 CD40LG MYOM2
10 cannabis dependence 10.2 CD40LG MYOM2
11 nerve compression syndrome 10.2 CD40LG MYOM2
12 west nile virus 10.2
13 generalized atherosclerosis 10.2 CD40LG MYOM2
14 bone deterioration disease 10.2 DICER1 KRAS
15 exudative glomerulonephritis 10.1 DICER1 KRAS
16 hemangioma of orbit 10.1 CD40LG IL2
17 thymic neuroendocrine carcinoma 10.1 IL2 MYOM2
18 acute allergic sanguinous otitis media 10.1 IL2 MYOM2
19 glomangiosarcoma 10.1 CD40LG MYOM2
20 gastrointestinal system benign neoplasm 10.1 KRAS RAF1
21 neuropathy, hereditary thermosensitive 10.1 CD40LG IL2
22 lipomatosis, multiple symmetric 10.1 CD40LG MYOM2
23 female breast nipple and areola cancer 10.1 CD40LG MYOM2
24 multinodular goiter 10.1 CD40LG IL2 KRAS
25 endogenous depression 10.0 CD40LG IL2 MYOM2
26 newcastle disease 10.0 CD40LG IL2 MYOM2
27 dermatitis herpetiformis 10.0 CD40LG ERVW-1
28 mumps 10.0 CD40LG ERVW-1 STAB2
29 louping ill 9.9
30 poliomyelitis 9.9
31 herpes simplex 9.9
32 yellow fever 9.9
33 herpes simplex encephalitis 9.9
34 huntington disease-like 1 9.9 PRNP THY1
35 anus leiomyosarcoma 9.9 CD40LG ERVW-1 IL2
36 exophthalmos 9.8 CD40LG ERVW-1 IL2
37 middle ear cholesterol granuloma 9.7 ERVW-1 KRAS RAF1 SNORA73B

Graphical network of the top 20 diseases related to Murray Valley Encephalitis:



Diseases related to Murray Valley Encephalitis

Symptoms & Phenotypes for Murray Valley Encephalitis

Symptoms:

12
  • fever
  • headache
  • nausea
  • vomiting
  • drowsiness
  • confusion
  • fitting
  • weakness

MGI Mouse Phenotypes related to Murray Valley Encephalitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.95 CD40LG DICER1 DROSHA IL2 KRAS RAF1
2 endocrine/exocrine gland MP:0005379 9.91 CD40LG DICER1 DROSHA IL2 KRAS PRNP
3 integument MP:0010771 9.8 DICER1 DROSHA KRAS PRNP RAF1 CD40LG
4 liver/biliary system MP:0005370 9.73 RAF1 STAB2 DICER1 DROSHA IL2 KRAS
5 neoplasm MP:0002006 9.55 DICER1 IL2 KRAS RAF1 STAB2
6 normal MP:0002873 9.5 DICER1 DROSHA KRAS PRNP RAF1 STAB2
7 respiratory system MP:0005388 9.17 DICER1 DROSHA IL2 KRAS RAF1 STAB2

Drugs & Therapeutics for Murray Valley Encephalitis

Search Clinical Trials , NIH Clinical Center for Murray Valley Encephalitis

Genetic Tests for Murray Valley Encephalitis

Anatomical Context for Murray Valley Encephalitis

MalaCards organs/tissues related to Murray Valley Encephalitis:

39
Brain, Testes, Neutrophil, B Cells, Kidney

The Foundational Model of Anatomy Ontology organs/tissues related to Murray Valley Encephalitis:

18
Brain

Publications for Murray Valley Encephalitis

Articles related to Murray Valley Encephalitis:

(show top 50) (show all 176)
id Title Authors Year
1
Long-term outcomes of Murray Valley encephalitis cases in Western Australia: what have we learnt? ( 26601912 )
2016
2
A Bayesian Belief Network for Murray Valley encephalitis virus risk assessment in Western Australia. ( 26823368 )
2016
3
Phylogeny of Murray Valley encephalitis virus in Australia and Papua New Guinea. ( 27086158 )
2016
4
Proteolytic cleavage analysis at the Murray Valley encephalitis virus NS1-2A junction. ( 26377679 )
2015
5
Viral neuronotropism is important in the pathogenesis of Murray Valley encephalitis. ( 26373772 )
2015
6
A case of Murray Valley encephalitis in a 2-year-old Australian Stock Horse in south-east Queensland. ( 25708787 )
2015
7
Visual detection of murray valley encephalitis virus by reverse transcription loop-mediated isothermal amplification. ( 25800449 )
2015
8
The Molecular Epidemiology and Evolution of Murray Valley Encephalitis Virus: Recent Emergence of Distinct Sub-lineages of the Dominant Genotype 1. ( 26600318 )
2015
9
Rainfall and sentinel chicken seroconversions predict human cases of Murray Valley encephalitis in the north of Western Australia. ( 25490948 )
2014
10
The changing epidemiology of Murray Valley encephalitis in Australia: the 2011 outbreak and a review of the literature. ( 24466360 )
2014
11
Complete genome sequences of the prototype isolates of genotypes 2, 3, and 4 of murray valley encephalitis virus. ( 24948762 )
2014
12
Substrate-based peptidomimetic inhibitors of the Murray Valley encephalitis virus NS2B/NS3 serine protease: a P1-P4 SAR study. ( 23974013 )
2013
13
Molecular characterization and phylogenetic analysis of Murray Valley encephalitis virus and West Nile virus (Kunjin subtype) from an arbovirus disease outbreak in horses in Victoria, Australia, in 2011. ( 23345269 )
2013
14
A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides. ( 24333681 )
2013
15
Low seroprevalence of Murray Valley encephalitis and Kunjin viruses in an opportunistic serosurvey, Victoria 2011. ( 24090325 )
2013
16
Clinical and radiological predictors of outcome for Murray Valley encephalitis. ( 23296449 )
2013
17
A new insect-specific flavivirus from northern Australia suppresses replication of West Nile virus and Murray Valley encephalitis virus in co-infected mosquito cells. ( 23460804 )
2013
18
Murray Valley encephalitis: a review of clinical features, diagnosis and treatment. ( 22432670 )
2012
19
Solid-phase synthesis and screening of a library of C-terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease. ( 22991186 )
2012
20
Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. ( 22379060 )
2012
21
Opportunistic serological surveillance for Murray Valley encephalitis virus in Victoria, February-May 2011. ( 22860790 )
2012
22
Biochemical characterisation of Murray Valley encephalitis virus proteinase. ( 20621842 )
2010
23
Factsheet: Murray Valley encephalitis. ( 21604606 )
2010
24
Live chimeric and inactivated Japanese encephalitis virus vaccines differ in their cross-protective values against Murray Valley encephalitis virus. ( 19109382 )
2009
25
Murray Valley encephalitis virus. ( 20191691 )
2009
26
Influence of hosts on the ecology of arboviral transmission: potential mechanisms influencing dengue, Murray Valley encephalitis, and Ross River virus in Australia. ( 18800866 )
2009
27
Murray Valley encephalitis in an adult traveller complicated by long-term flaccid paralysis: case report and review of the literature. ( 17161855 )
2007
28
Structure of the Murray Valley encephalitis virus RNA helicase at 1.9 Angstrom resolution. ( 17893366 )
2007
29
In situ reactions of monoclonal antibodies with a viable mutant of Murray Valley encephalitis virus reveal an absence of dimeric NS1 protein. ( 17374761 )
2007
30
Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. ( 17622627 )
2007
31
Genetic and phenotypic differences between isolates of Murray Valley encephalitis virus in Western Australia, 1972-2003. ( 17393295 )
2007
32
Murray valley encephalitis mimicking herpes simplex encephalitis. ( 16169227 )
2005
33
Virus spread, tissue inflammation and antiviral response in brains of flavivirus susceptible and resistant mice acutely infected with Murray Valley encephalitis virus. ( 14991436 )
2004
34
Antibody-dependent enhancement of Murray Valley encephalitis virus virulence in mice. ( 12810865 )
2003
35
Epizootic activity of Murray Valley encephalitis and Kunjin viruses in an aboriginal community in the southeast Kimberley region of Western Australia: results of mosquito fauna and virus isolation studies. ( 14628944 )
2003
36
Murray Valley encephalitis: case report and review of neuroradiological features. ( 12581057 )
2003
37
Polymerase chain reaction tests for the identification of Ross River, Kunjin and Murray Valley encephalitis virus infections in horses. ( 15084017 )
2003
38
MR findings in Murray Valley encephalitis. ( 12917132 )
2003
39
Clinical and laboratory findings on the first imported case of Murray Valley encephalitis in Europe. ( 12856229 )
2003
40
Investigation of the southern limits of Murray Valley encephalitis activity in Western Australia during the 2000 wet season. ( 12653302 )
2002
41
Epizootic activity of Murray Valley encephalitis virus in an aboriginal community in the southeast Kimberley region of Western Australia: results of cross-sectional and longitudinal serologic studies. ( 12408675 )
2002
42
Mechanism of virulence attenuation of glycosaminoglycan-binding variants of Japanese encephalitis virus and Murray Valley encephalitis virus. ( 11967307 )
2002
43
Reappearance of human cases due to Murray Valley encephalitis virus and Kunjin virus in central Australia after an absence of 26 years. ( 11950201 )
2002
44
Murray Valley encephalitis virus recombinant subviral particles protect mice from lethal challenge with virulent wild-type virus. ( 12111426 )
2002
45
Murray Valley encephalitis (Australian encephalitis): FactSheet. ( 12105611 )
2001
46
Murray Valley encephalitis in Mt Isa, north Queensland. Tropical Public Health Unit Network, Queensland Health. ( 11432525 )
2001
47
Attenuation of Murray Valley encephalitis virus by site-directed mutagenesis of the hinge and putative receptor-binding regions of the envelope protein. ( 11462041 )
2001
48
Murray Valley encephalitis virus surveillance and control initiatives in Australia. National Arbovirus Advisory Committee of the Communicable Diseases Network Australia. ( 11432524 )
2001
49
Determination of the intramolecular disulfide bond arrangement and biochemical identification of the glycosylation sites of the nonstructural protein NS1 of Murray Valley encephalitis virus. ( 11514736 )
2001
50
Murray valley encephalitis. ( 11596721 )
2001

Variations for Murray Valley Encephalitis

Expression for Murray Valley Encephalitis

Search GEO for disease gene expression data for Murray Valley Encephalitis.

Pathways for Murray Valley Encephalitis

GO Terms for Murray Valley Encephalitis

Cellular components related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 anchored component of external side of plasma membrane GO:0031362 8.62 PRNP THY1

Biological processes related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.62 CD40LG IL2 PRNP RAF1
2 positive regulation of protein phosphorylation GO:0001934 9.43 IL2 KRAS RAF1
3 negative regulation of T cell receptor signaling pathway GO:0050860 9.16 PRNP THY1
4 miRNA metabolic process GO:0010586 8.96 DICER1 DROSHA
5 pre-miRNA processing GO:0031054 8.62 DICER1 DROSHA

Molecular functions related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endoribonuclease activity GO:0004521 8.96 DICER1 DROSHA
2 ribonuclease III activity GO:0004525 8.62 DICER1 DROSHA

Sources for Murray Valley Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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