MCID: MRR003
MIFTS: 35

Murray Valley Encephalitis malady

Infectious category

Summaries for Murray Valley Encephalitis

Sources:
8Disease Ontology, 33MalaCards
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Disease Ontology:8 A viral infectious disease that results in inflammation located in brain, has material basis in murray valley encephalitis virus, which is transmitted by culex annulirostris mosquitoes. the infection has symptom fever, has symptom headache, has symptom nausea, has symptom vomiting, has symptom drowsiness, has symptom confusion, has symptom fitting, and has symptom weakness.

MalaCards: Murray Valley Encephalitis, also known as australian encephalitis, is related to yellow fever and kunjin encephalitis, and has symptoms including fever, headache and nausea. An important gene associated with Murray Valley Encephalitis is RAF1 (v-raf-1 murine leukemia viral oncogene homolog 1), and among its related pathways are NCAM signaling for neurite out-growth and SHC1 events in ERBB2 signaling. The compound pd-184352 have been mentioned in the context of this disorder. Affiliated tissues include brain, brain and kidney.

Aliases & Classifications for Murray Valley Encephalitis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 27ICD9CM, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Aliases & Descriptions:

murray valley encephalitis 8 10 61
australian encephalitis 8
australian x disease 8


External Ids:

Disease Ontology8 DOID:10842
ICD9CM27 062.4
SNOMED-CT57 66454007
ICD1025 A83.4

Related Diseases for Murray Valley Encephalitis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Murray Valley Encephalitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 15)
idRelated DiseaseScoreTop Affiliating Genes
1yellow fever30.4KRAS, RAF1
2kunjin encephalitis10.9
3japanese encephalitis10.8
4west nile encephalitis10.8
5west nile virus10.8
6viral encephalitis10.5
7herpes simplex encephalitis10.3
8cardiofaciocutaneous syndrome10.0KRAS
9encephalitis10.0RAF1
10tick-borne encephalitis10.0RAF1
11juvenile myelomonocytic leukemia10.0KRAS
12dengue disease10.0RAF1, KRAS
13factor vii deficiency10.0KRAS, RAF1
14neurofibromatosis10.0RAF1, KRAS
15noonan syndrome10.0KRAS, RAF1

Graphical network of diseases related to Murray Valley Encephalitis:



Diseases related to murray valley encephalitis

Clinical Features for Murray Valley Encephalitis

Sources:
8Disease Ontology
See all sources


Symptoms:

8 (show all 8)
  • fever
  • headache
  • nausea
  • vomiting
  • weakness
  • confusion
  • drowsiness
  • fitting

Drugs & Therapeutics for Murray Valley Encephalitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Murray Valley Encephalitis

Drug clinical trials:

Search ClinicalTrials for Murray Valley Encephalitis

Search NIH Clinical Center for Murray Valley Encephalitis

Search CenterWatch for Murray Valley Encephalitis

Genetic Tests for Murray Valley Encephalitis

Anatomical Context for Murray Valley Encephalitis

Sources:
14FMA, 33MalaCards
See all sources

MalaCards organs/tissues related to Murray Valley Encephalitis:

33
Brain, Kidney, T cells, B cells

FMA organs/tissues related to Murray Valley Encephalitis:

14
Brain

Animal Models for Murray Valley Encephalitis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Murray Valley Encephalitis

Sources:
51PubMed
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Articles related to Murray Valley Encephalitis:

(show top 50)    (show all 165)
idTitleAuthorsYear
1
A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides. (24333681)
2013
2
Murray Valley encephalitis: a review of clinical features, diagnosis and treatment. (22432670)
2012
3
Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. (22379060)
2012
4
Opportunistic serological surveillance for Murray Valley encephalitis virus in Victoria, February-May 2011. (22860790)
2012
5
In situ reactions of monoclonal antibodies with a viable mutant of Murray Valley encephalitis virus reveal an absence of dimeric NS1 protein. (17374761)
2007
6
Murray valley encephalitis mimicking herpes simplex encephalitis. (16169227)
2005
7
Virus spread, tissue inflammation and antiviral response in brains of flavivirus susceptible and resistant mice acutely infected with Murray Valley encephalitis virus. (14991436)
2004
8
Murray Valley encephalitis: case report and review of neuroradiological features. (12581057)
2003
9
Attenuation of Murray Valley encephalitis virus by site-directed mutagenesis of the hinge and putative receptor-binding regions of the envelope protein. (11462041)
2001
10
Murray Valley encephalitis in Mt Isa, north Queensland. Tropical Public Health Unit Network, Queensland Health. (11432525)
2001
11
Murray Valley encephalitis in Western Australia in 2000, with evidence of southerly spread. (11225378)
2000
12
Morphological features of Murray Valley encephalitis virus infection in the central nervous system of Swiss mice. (10718862)
2000
13
Molecular characterization of virus-specific RNA produced in the brains of flavivirus-susceptible and -resistant mice after challenge with Murray Valley encephalitis virus. (9010281)
1997
14
Protective immune responses to the E and NS1 proteins of Murray Valley encephalitis virus in hybrids of flavivirus-resistant mice. (8683218)
1996
15
Neurovirulence and neuroinvasiveness of Murray Valley encephalitis virus mutants selected by passage in a monkey kidney cell line. (9049332)
1995
16
Australian X disease, Murray Valley encephalitis and the French connection. (8545982)
1995
17
A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes. (1383567)
1992
18
Persistent infection of Vero cells by the flavivirus Murray Valley encephalitis virus. (1848592)
1991
19
Epitope analysis of the envelope and non-structural glycoproteins of Murray Valley encephalitis virus. (1703213)
1990
20
Host cell selection of Murray Valley encephalitis virus variants altered at an RGD sequence in the envelope protein and in mouse virulence. (2161151)
1990
21
Larval diet and the vector competence of Culex annulirostris (Diptera: Culicidae) for Murray Valley encephalitis virus. (2552121)
1989
22
The vector competence of Culex annulirostris, Aedes sagax and Aedes alboannulatus for Murray Valley encephalitis virus at different temperatures. (2562418)
1989
23
Type-specific monoclonal antibodies produced to proteins of Murray Valley encephalitis virus. (2453454)
1988
24
Comparison of proteins specified by Murray Valley encephalitis, West Nile, Japanese encephalitis and St. Louis encephalitis viruses. (3579743)
1986
25
Genetic differentiation of Murray Valley encephalitis virus in Australia and Papua New Guinea. (2884985)
1986
26
The vector competence of Australian Culex annulirostris with Murray Valley encephalitis and Kunjin viruses. (6100042)
1984
27
Primary viraemia responses of herons to experimental infection with Murray Valley encephalitis, Kunjin and Japanese encephalitis viruses. (6326724)
1983
28
Comparisons by peptide mapping of proteins specified by Kunjin, West Nile and Murray Valley encephalitis viruses. (6326723)
1983
29
Vector competence of Culex pipiens quinquefasciatus for Murray Valley encephalitis, Kunjin, and Ross River viruses from Australia. (6285750)
1982
30
Murray Valley encephalitis in Australia, 1974: antibody response in cases and community. (1071876)
1976
31
Murray Valley encephalitis, 1974: clinical features. (994930)
1976
32
The proteins of Murray Valley encephalitis virus. (806663)
1975
33
Letter: Murray Valley encephalitis virus in Eastern Australia, 1971. (4758166)
1973
34
A fatal case of Murray Valley encephalitis. (5430492)
1970
35
Studies of the morphology of Murray Valley encephalitis and Japanese encephalitis viruses growing in cultured mosquito cells. (5651024)
1968
36
Particle counts and some chemical properties of Murray Valley encephalitis virus. (13859227)
1962
37
The action of phospholipase A and lipid solvents on Murray Valley encephalitis virus. (13683281)
1961
38
Purification of Murray Valley encephalitis virus. (13681287)
1961
39
A lipid component of Murray Valley encephalitis virus. (13683280)
1960
40
Some aspects of the reaction between crude Murray Valley encephalitis (MVE) virus and deoxycholate. (13669348)
1959
41
Murray Valley encephalitis in the Murray Valley, 1956 and 1957. (13565011)
1958
42
Murray Valley encephalitis virus: its serological relationship to the Japanese-West Nile-St. Louis encephalitis group of viruses. (13242806)
1955
43
A note on the persistence and distribution of antibodies to Murray Valley encephalitis in man in South Australia. (13234951)
1955
44
Transmission of Murray Valley encephalitis virus by mosquitoes. (13115309)
1953
45
Murray Valley encephalitis: a survey of avian sera, 1951-1952. (13062866)
1953
46
Murray Valley encephalitis; clinical aspects. (14909903)
1952
47
Poliomyelitis and Murray Valley encephalitis; a comparison of two neurotropic virus diseases. (14909922)
1952
48
MURRAY Valley encephalitis. (13001561)
1952
49
Murray Valley encephalitis; epidemiological aspects. (14909901)
1952
50
MURRAY Valley encephalitis. (14833187)
1951

Genetic Variations for Murray Valley Encephalitis

Expression for genes affiliated with Murray Valley Encephalitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Murray Valley Encephalitis

Search GEO for disease gene expression data for Murray Valley Encephalitis.

Pathways for genes affiliated with Murray Valley Encephalitis

Sources:
54Reactome, 38NCBI BioSystems Database, 50PharmGKB, 56SinoBiological, 30KEGG, 12EMD Millipore
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Compounds for genes affiliated with Murray Valley Encephalitis

Sources:
45Novoseek
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Compounds related to Murray Valley Encephalitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1pd-184352459.8KRAS, RAF1

GO Terms for genes affiliated with Murray Valley Encephalitis

Sources:
16Gene Ontology
See all sources

Biological processes related to Murray Valley Encephalitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Ras protein signal transductionGO:0072659.8KRAS, RAF1
2activation of MAPKK activityGO:0001869.7KRAS, RAF1
3MAPK cascadeGO:0001659.5KRAS, RAF1

Products for genes affiliated with Murray Valley Encephalitis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Murray Valley Encephalitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet