MCID: MRR003
MIFTS: 39

Murray Valley Encephalitis malady

Category: Infectious diseases

Aliases & Classifications for Murray Valley Encephalitis

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Aliases & Descriptions for Murray Valley Encephalitis:

Name: Murray Valley Encephalitis 11 13 68
Australian Encephalitis 11
 
Australian X Disease 11

Classifications:



External Ids:

Disease Ontology11 DOID:10842
ICD1030 A83.4
SNOMED-CT62 66454007
ICD9CM32 062.4

Summaries for Murray Valley Encephalitis

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Disease Ontology:11 A viral infectious disease that results in inflammation located in brain, has material basis in Murray Valley encephalitis virus, which is transmitted by Culex annulirostris mosquitoes. The infection has symptom fever, has symptom headache, has symptom nausea, has symptom vomiting, has symptom drowsiness, has symptom confusion, has symptom fitting, and has symptom weakness.

MalaCards based summary: Murray Valley Encephalitis, also known as australian encephalitis, is related to st. louis encephalitis and encephalitis, and has symptoms including fever, headache and nausea. An important gene associated with Murray Valley Encephalitis is RAF1 (Raf-1 Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways are G-protein signaling_K-RAS regulation pathway and Extracellular vesicle-mediated signaling in recipient cells. Affiliated tissues include brain, brain and testes, and related mouse phenotypes are neoplasm and integument.

Related Diseases for Murray Valley Encephalitis

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Diseases related to Murray Valley Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
idRelated DiseaseScoreTop Affiliating Genes
1st. louis encephalitis27.8CD40LG, DICER1, DROSHA, ERVW-1, IL2, KRAS
2encephalitis11.1
3japanese encephalitis10.4
4pseudomonas stutzeri infections10.3KRAS, RAF1
5erysipelas10.3CD40LG, RAF1
6rdh12-related leber congenital amaurosis10.3KRAS, RAF1
7relapsing-remitting multiple sclerosis10.3CD40LG, STAB2
8syndactyly-polydactyly-earlobe syndrome10.2KRAS, RAF1
9jaw cancer10.2CD40LG, MYOM2
10cannabis dependence10.2CD40LG, MYOM2
11nerve compression syndrome10.2CD40LG, MYOM2
12west nile virus10.2
13generalized atherosclerosis10.2CD40LG, MYOM2
14bone deterioration disease10.2DICER1, KRAS
15exudative glomerulonephritis10.1DICER1, KRAS
16hemangioma of orbit10.1CD40LG, IL2
17thymic neuroendocrine carcinoma10.1IL2, MYOM2
18acute allergic sanguinous otitis media10.1IL2, MYOM2
19glomangiosarcoma10.1CD40LG, MYOM2
20gastrointestinal system benign neoplasm10.1KRAS, RAF1
21neuropathy, hereditary thermosensitive10.1CD40LG, IL2
22lipomatosis, multiple symmetric10.1CD40LG, MYOM2
23female breast nipple and areola cancer10.1CD40LG, MYOM2
24multinodular goiter10.1CD40LG, IL2, KRAS
25endogenous depression10.0CD40LG, IL2, MYOM2
26newcastle disease10.0CD40LG, IL2, MYOM2
27dermatitis herpetiformis10.0CD40LG, ERVW-1
28mumps10.0CD40LG, ERVW-1, STAB2
29louping ill9.9
30poliomyelitis9.9
31herpes simplex9.9
32yellow fever9.9
33herpes simplex encephalitis9.9
34huntington disease-like 19.9PRNP, THY1
35anus leiomyosarcoma9.9CD40LG, ERVW-1, IL2
36exophthalmos9.8CD40LG, ERVW-1, IL2
37middle ear cholesterol granuloma9.7ERVW-1, KRAS, RAF1, SNORA73B

Graphical network of the top 20 diseases related to Murray Valley Encephalitis:



Diseases related to murray valley encephalitis

Symptoms & Phenotypes for Murray Valley Encephalitis

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Symptoms:

 11 (show all 8)
  • fever
  • headache
  • nausea
  • vomiting
  • drowsiness
  • confusion
  • fitting
  • weakness

MGI Mouse Phenotypes related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.5DICER1, IL2, KRAS, RAF1, STAB2
2MP:00107719.2CD40LG, DICER1, DROSHA, KRAS, PRNP, RAF1
3MP:00053709.2DICER1, DROSHA, IL2, KRAS, RAF1, STAB2
4MP:00053858.9CD40LG, DICER1, DROSHA, IL2, KRAS, RAF1
5MP:00053798.7CD40LG, DICER1, DROSHA, IL2, KRAS, PRNP
6MP:00028738.6DICER1, DROSHA, KRAS, PRNP, RAF1, STAB2
7MP:00053887.9DICER1, DROSHA, IL2, KRAS, RAF1, STAB2

Drugs & Therapeutics for Murray Valley Encephalitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Murray Valley Encephalitis

Genetic Tests for Murray Valley Encephalitis

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Anatomical Context for Murray Valley Encephalitis

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MalaCards organs/tissues related to Murray Valley Encephalitis:

36
Brain, Testes, Neutrophil, B cells, Kidney

FMA organs/tissues related to Murray Valley Encephalitis:

17
Brain

Publications for Murray Valley Encephalitis

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Articles related to Murray Valley Encephalitis:

(show top 50)    (show all 176)
idTitleAuthorsYear
1
Long-term outcomes of Murray Valley encephalitis cases in Western Australia: what have we learnt? (26601912)
2016
2
A Bayesian Belief Network for Murray Valley encephalitis virus risk assessment in Western Australia. (26823368)
2016
3
Phylogeny of Murray Valley encephalitis virus in Australia and Papua New Guinea. (27086158)
2016
4
Proteolytic cleavage analysis at the Murray Valley encephalitis virus NS1-2A junction. (26377679)
2015
5
Viral neuronotropism is important in the pathogenesis of Murray Valley encephalitis. (26373772)
2015
6
A case of Murray Valley encephalitis in a 2-year-old Australian Stock Horse in south-east Queensland. (25708787)
2015
7
Visual detection of murray valley encephalitis virus by reverse transcription loop-mediated isothermal amplification. (25800449)
2015
8
The Molecular Epidemiology and Evolution of Murray Valley Encephalitis Virus: Recent Emergence of Distinct Sub-lineages of the Dominant Genotype 1. (26600318)
2015
9
Rainfall and sentinel chicken seroconversions predict human cases of Murray Valley encephalitis in the north of Western Australia. (25490948)
2014
10
The changing epidemiology of Murray Valley encephalitis in Australia: the 2011 outbreak and a review of the literature. (24466360)
2014
11
Complete genome sequences of the prototype isolates of genotypes 2, 3, and 4 of murray valley encephalitis virus. (24948762)
2014
12
Substrate-based peptidomimetic inhibitors of the Murray Valley encephalitis virus NS2B/NS3 serine protease: a P1-P4 SAR study. (23974013)
2013
13
Molecular characterization and phylogenetic analysis of Murray Valley encephalitis virus and West Nile virus (Kunjin subtype) from an arbovirus disease outbreak in horses in Victoria, Australia, in 2011. (23345269)
2013
14
A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides. (24333681)
2013
15
Low seroprevalence of Murray Valley encephalitis and Kunjin viruses in an opportunistic serosurvey, Victoria 2011. (24090325)
2013
16
Clinical and radiological predictors of outcome for Murray Valley encephalitis. (23296449)
2013
17
A new insect-specific flavivirus from northern Australia suppresses replication of West Nile virus and Murray Valley encephalitis virus in co-infected mosquito cells. (23460804)
2013
18
Murray Valley encephalitis: a review of clinical features, diagnosis and treatment. (22432670)
2012
19
Solid-phase synthesis and screening of a library of C-terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease. (22991186)
2012
20
Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. (22379060)
2012
21
Opportunistic serological surveillance for Murray Valley encephalitis virus in Victoria, February-May 2011. (22860790)
2012
22
Biochemical characterisation of Murray Valley encephalitis virus proteinase. (20621842)
2010
23
Factsheet: Murray Valley encephalitis. (21604606)
2010
24
Live chimeric and inactivated Japanese encephalitis virus vaccines differ in their cross-protective values against Murray Valley encephalitis virus. (19109382)
2009
25
Murray Valley encephalitis virus. (20191691)
2009
26
Influence of hosts on the ecology of arboviral transmission: potential mechanisms influencing dengue, Murray Valley encephalitis, and Ross River virus in Australia. (18800866)
2009
27
Murray Valley encephalitis in an adult traveller complicated by long-term flaccid paralysis: case report and review of the literature. (17161855)
2007
28
Structure of the Murray Valley encephalitis virus RNA helicase at 1.9 Angstrom resolution. (17893366)
2007
29
In situ reactions of monoclonal antibodies with a viable mutant of Murray Valley encephalitis virus reveal an absence of dimeric NS1 protein. (17374761)
2007
30
Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. (17622627)
2007
31
Genetic and phenotypic differences between isolates of Murray Valley encephalitis virus in Western Australia, 1972-2003. (17393295)
2007
32
Murray valley encephalitis mimicking herpes simplex encephalitis. (16169227)
2005
33
Virus spread, tissue inflammation and antiviral response in brains of flavivirus susceptible and resistant mice acutely infected with Murray Valley encephalitis virus. (14991436)
2004
34
Antibody-dependent enhancement of Murray Valley encephalitis virus virulence in mice. (12810865)
2003
35
Epizootic activity of Murray Valley encephalitis and Kunjin viruses in an aboriginal community in the southeast Kimberley region of Western Australia: results of mosquito fauna and virus isolation studies. (14628944)
2003
36
Murray Valley encephalitis: case report and review of neuroradiological features. (12581057)
2003
37
Polymerase chain reaction tests for the identification of Ross River, Kunjin and Murray Valley encephalitis virus infections in horses. (15084017)
2003
38
MR findings in Murray Valley encephalitis. (12917132)
2003
39
Clinical and laboratory findings on the first imported case of Murray Valley encephalitis in Europe. (12856229)
2003
40
Investigation of the southern limits of Murray Valley encephalitis activity in Western Australia during the 2000 wet season. (12653302)
2002
41
Epizootic activity of Murray Valley encephalitis virus in an aboriginal community in the southeast Kimberley region of Western Australia: results of cross-sectional and longitudinal serologic studies. (12408675)
2002
42
Mechanism of virulence attenuation of glycosaminoglycan-binding variants of Japanese encephalitis virus and Murray Valley encephalitis virus. (11967307)
2002
43
Reappearance of human cases due to Murray Valley encephalitis virus and Kunjin virus in central Australia after an absence of 26 years. (11950201)
2002
44
Murray Valley encephalitis virus recombinant subviral particles protect mice from lethal challenge with virulent wild-type virus. (12111426)
2002
45
Murray Valley encephalitis (Australian encephalitis): FactSheet. (12105611)
2001
46
Murray Valley encephalitis in Mt Isa, north Queensland. Tropical Public Health Unit Network, Queensland Health. (11432525)
2001
47
Attenuation of Murray Valley encephalitis virus by site-directed mutagenesis of the hinge and putative receptor-binding regions of the envelope protein. (11462041)
2001
48
Murray Valley encephalitis virus surveillance and control initiatives in Australia. National Arbovirus Advisory Committee of the Communicable Diseases Network Australia. (11432524)
2001
49
Determination of the intramolecular disulfide bond arrangement and biochemical identification of the glycosylation sites of the nonstructural protein NS1 of Murray Valley encephalitis virus. (11514736)
2001
50
Murray valley encephalitis. (11596721)
2001

Variations for Murray Valley Encephalitis

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Expression for genes affiliated with Murray Valley Encephalitis

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Search GEO for disease gene expression data for Murray Valley Encephalitis.

Pathways for genes affiliated with Murray Valley Encephalitis

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GO Terms for genes affiliated with Murray Valley Encephalitis

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Cellular components related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1anchored component of external side of plasma membraneGO:00313629.5PRNP, THY1

Biological processes related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1miRNA metabolic processGO:001058610.4DICER1, DROSHA
2negative regulation of T cell receptor signaling pathwayGO:005086010.1PRNP, THY1
3pre-miRNA processingGO:00310549.8DICER1, DROSHA
4positive regulation of protein phosphorylationGO:00019349.7IL2, KRAS, RAF1
5negative regulation of apoptotic processGO:00430669.5CD40LG, IL2, PRNP, RAF1

Molecular functions related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endoribonuclease activityGO:00045219.8DICER1, DROSHA
2ribonuclease III activityGO:00045259.8DICER1, DROSHA

Sources for Murray Valley Encephalitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet