MCID: MRR003
MIFTS: 37

Murray Valley Encephalitis malady

Infectious diseases category

Summaries for Murray Valley Encephalitis

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A viral infectious disease that results in inflammation located in brain, has material basis in murray valley encephalitis virus, which is transmitted by culex annulirostris mosquitoes. the infection has symptom fever, has symptom headache, has symptom nausea, has symptom vomiting, has symptom drowsiness, has symptom confusion, has symptom fitting, and has symptom weakness.

MalaCards: Murray Valley Encephalitis, also known as australian encephalitis, is related to encephalitis and yellow fever, and has symptoms including weakness, fitting and confusion. An important gene associated with Murray Valley Encephalitis is RAF1 (v-raf-1 murine leukemia viral oncogene homolog 1), and among its related pathways are NCAM signaling for neurite out-growth and SHC1 events in ERBB2 signaling. The compound pd-184352 have been mentioned in the context of this disorder. Affiliated tissues include brain, brain and testes.

Aliases & Classifications for Murray Valley Encephalitis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

murray valley encephalitis 8 10 60
australian encephalitis 8
australian x disease 8


External Ids:

Disease Ontology8 DOID:10842
ICD9CM27 062.4
SNOMED-CT56 66454007
ICD1025 A83.4

Related Diseases for Murray Valley Encephalitis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Murray Valley Encephalitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1encephalitis32.1RAF1
2yellow fever30.4KRAS, RAF1
3kunjin encephalitis10.8
4japanese encephalitis10.8
5west nile encephalitis10.7
6st. louis encephalitis10.5
7viral encephalitis10.5
8louping ill10.3
9herpes simplex10.3
10poliomyelitis10.3
11cardiofaciocutaneous syndrome10.0KRAS
12tick-borne encephalitis10.0RAF1
13juvenile myelomonocytic leukemia10.0KRAS
14dengue disease10.0RAF1, KRAS
15factor vii deficiency10.0KRAS, RAF1
16neurofibromatosis10.0RAF1, KRAS
17noonan syndrome10.0KRAS, RAF1

Graphical network of diseases related to Murray Valley Encephalitis:



Diseases related to murray valley encephalitis

Clinical Features for Murray Valley Encephalitis

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Sources:
8Disease Ontology
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Symptoms:

8 (show all 8)
  • weakness
  • fitting
  • confusion
  • drowsiness
  • vomiting
  • nausea
  • headache
  • fever

Drugs & Therapeutics for Murray Valley Encephalitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Murray Valley Encephalitis

Drug clinical trials:

Search ClinicalTrials for Murray Valley Encephalitis

Search NIH Clinical Center for Murray Valley Encephalitis

Search CenterWatch for Murray Valley Encephalitis

Genetic Tests for Murray Valley Encephalitis

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Anatomical Context for Murray Valley Encephalitis

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Murray Valley Encephalitis:

32
Brain, Testes, B cells, Kidney

FMA organs/tissues related to Murray Valley Encephalitis:

14
Brain

Animal Models for Murray Valley Encephalitis or affiliated genes

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Publications for Murray Valley Encephalitis

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Sources:
50PubMed
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Articles related to Murray Valley Encephalitis:

(show top 50)    (show all 165)
idTitleAuthorsYear
1
A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides. (24333681)
2013
2
A new insect-specific flavivirus from northern Australia suppresses replication of West Nile virus and Murray Valley encephalitis virus in co-infected mosquito cells. (23460804)
2013
3
Solid-phase synthesis and screening of a library of C-terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease. (22991186)
2012
4
Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. (22379060)
2012
5
Opportunistic serological surveillance for Murray Valley encephalitis virus in Victoria, February-May 2011. (22860790)
2012
6
Biochemical characterisation of Murray Valley encephalitis virus proteinase. (20621842)
2010
7
Factsheet: Murray Valley encephalitis. (21604606)
2010
8
Live chimeric and inactivated Japanese encephalitis virus vaccines differ in their cross-protective values against Murray Valley encephalitis virus. (19109382)
2009
9
Influence of hosts on the ecology of arboviral transmission: potential mechanisms influencing dengue, Murray Valley encephalitis, and Ross River virus in Australia. (18800866)
2009
10
Murray Valley encephalitis in an adult traveller complicated by long-term flaccid paralysis: case report and review of the literature. (17161855)
2007
11
In situ reactions of monoclonal antibodies with a viable mutant of Murray Valley encephalitis virus reveal an absence of dimeric NS1 protein. (17374761)
2007
12
Virus spread, tissue inflammation and antiviral response in brains of flavivirus susceptible and resistant mice acutely infected with Murray Valley encephalitis virus. (14991436)
2004
13
Clinical and laboratory findings on the first imported case of Murray Valley encephalitis in Europe. (12856229)
2003
14
Mechanism of virulence attenuation of glycosaminoglycan-binding variants of Japanese encephalitis virus and Murray Valley encephalitis virus. (11967307)
2002
15
Attenuation of Murray Valley encephalitis virus by site-directed mutagenesis of the hinge and putative receptor-binding regions of the envelope protein. (11462041)
2001
16
Murray Valley encephalitis in Western Australia in 2000, with evidence of southerly spread. (11225378)
2000
17
Early diagnosis of Murray Valley encephalitis by reverse transcriptase-polymerase chain reaction. (10740807)
2000
18
Immune response to a Murray Valley encephalitis virus epitope expressed in the flagellin of an attenuated strain of Salmonella. (9060872)
1997
19
Protective immune responses to the E and NS1 proteins of Murray Valley encephalitis virus in hybrids of flavivirus-resistant mice. (8683218)
1996
20
Two possible mechanisms for survival and initiation of Murray Valley encephalitis virus activity in the Kimberley region of Western Australia. (7625542)
1995
21
Murray valley encephalitis virus envelope protein antigenic variants with altered hemagglutination properties and reduced neuroinvasiveness in mice. (7645203)
1995
22
A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes. (1383567)
1992
23
Immunoaffinity purification of the NS1 protein of Murray Valley encephalitis virus: selection of the appropriate ligand and optimal conditions for elution. (1648569)
1991
24
Murray Valley encephalitis acquired in Western Australia. (1645843)
1991
25
Epitope analysis of the envelope and non-structural glycoproteins of Murray Valley encephalitis virus. (1703213)
1990
26
The 5'-terminal non-coding region of Murray Valley encephalitis virus RNA is highly conserved. (2154536)
1990
27
Larval diet and the vector competence of Culex annulirostris (Diptera: Culicidae) for Murray Valley encephalitis virus. (2552121)
1989
28
The vector competence of Culex annulirostris, Aedes sagax and Aedes alboannulatus for Murray Valley encephalitis virus at different temperatures. (2562418)
1989
29
The experimental infection of horses with Murray Valley encephalitis and Ross River viruses. (3038067)
1987
30
A mathematical model for the rural amplification of Murray Valley encephalitis virus in southern Australia. (3826047)
1987
31
Comparison of proteins specified by Murray Valley encephalitis, West Nile, Japanese encephalitis and St. Louis encephalitis viruses. (3579743)
1986
32
Partial nucleotide sequence of the Murray Valley encephalitis virus genome. Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins. (3009829)
1986
33
The vector competence of Australian Culex annulirostris with Murray Valley encephalitis and Kunjin viruses. (6100042)
1984
34
Primary viraemia responses of herons to experimental infection with Murray Valley encephalitis, Kunjin and Japanese encephalitis viruses. (6326724)
1983
35
Primary antibody responses of herons to experimental infection with Murray Valley encephalitis and Kunjin viruses. (6326725)
1983
36
Isolation of Murray Valley encephalitis virus and other arboviruses in the Ord River Valley 1972-1976. (6117274)
1981
37
Towards prediction and surveillance of Murray Valley encephalitis activity in Australia. (6255919)
1980
38
Quantitative studies of the vector competence of Aedes aegypti, Culex annulirostris and other mosquitoes (Diptera: Culicidae) with Murray Valley encephalitis and other Queensland arboviruses. (42801)
1979
39
Isolation of Murray Valley encephalitis virus from the brains of three patients with encephalitis. (994931)
1976
40
Murray Valley encephalitis virus infection in mosquitoes and domestic fowls in Queensland, 1974. (13773)
1976
41
Isolation of Murray Valley encephalitis virus from sentinel chickens. (1164265)
1975
42
Intratypic antigenic variation among strains of the group B arboviruses Murray Valley encephalitis and Kunjin. (4997354)
1971
43
ARTHROPOD-BORNE VIRUS INFECTIONS IN WESTERN NEW GUINEA. I. REPORT OF A CASE OF MURRAY VALLEY ENCEPHALITIS IN A PAPUAN WOMAN. (14317227)
1965
44
THE BEHAVIOR OF MURRAY VALLEY ENCEPHALITIS VIRUS IN CULEX TRITAENIORHYNCHUS GILES AND CULEX PIPIENS QUINQUEFASCIATUS SAY. (14044755)
1963
45
Purification of Murray Valley encephalitis virus. (13681287)
1961
46
Murray Valley encephalitis virus: preparation of an infective "ribonucleic acid" fraction. (13793450)
1959
47
Murray Valley encephalitis in the Murray Valley, 1956 and 1957. (13565011)
1958
48
Transmission of the virus of Murray Valley encephalitis by Culex tarsalis Coquillett, Aedes polynesiensis Marks, and A. pseudoscutellaris Theobald. (13302203)
1956
49
Murray Valley encephalitis: a survey of suspected mosquito vectors. (13114600)
1954
50
Poliomyelitis and Murray Valley encephalitis; a comparison of two neurotropic virus diseases. (14909922)
1952

Genetic Variations for Murray Valley Encephalitis

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Expression for genes affiliated with Murray Valley Encephalitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Murray Valley Encephalitis

Search GEO for disease gene expression data for Murray Valley Encephalitis.

Pathways for genes affiliated with Murray Valley Encephalitis

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Sources:
53Reactome, 37NCBI BioSystems Database, 49PharmGKB, 55SinoBiological, 29KEGG, 12EMD Millipore
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Compounds for genes affiliated with Murray Valley Encephalitis

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44Novoseek
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Compounds related to Murray Valley Encephalitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1pd-184352449.8KRAS, RAF1

GO Terms for genes affiliated with Murray Valley Encephalitis

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16Gene Ontology
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Biological processes related to Murray Valley Encephalitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Ras protein signal transductionGO:0072659.8KRAS, RAF1
2activation of MAPKK activityGO:0001869.7KRAS, RAF1
3MAPK cascadeGO:0001659.5KRAS, RAF1

Products for genes affiliated with Murray Valley Encephalitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Murray Valley Encephalitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet