MCID: MRR003
MIFTS: 39

Murray Valley Encephalitis malady

Infectious diseases, Neuronal diseases categories

Aliases & Classifications for Murray Valley Encephalitis

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Aliases & Descriptions for Murray Valley Encephalitis:

Name: Murray Valley Encephalitis 10 12 65
Australian Encephalitis 10
 
Australian X Disease 10


Classifications:



External Ids:

Disease Ontology10 DOID:10842
ICD9CM29 062.4
SNOMED-CT59 66454007
ICD1027 A83.4

Summaries for Murray Valley Encephalitis

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Disease Ontology:10 A viral infectious disease that results in inflammation located in brain, has material basis in murray valley encephalitis virus, which is transmitted by culex annulirostris mosquitoes. the infection has symptom fever, has symptom headache, has symptom nausea, has symptom vomiting, has symptom drowsiness, has symptom confusion, has symptom fitting, and has symptom weakness.

MalaCards based summary: Murray Valley Encephalitis, also known as australian encephalitis, is related to encephalitis and japanese encephalitis, and has symptoms including fever, headache and nausea. An important gene associated with Murray Valley Encephalitis is RAF1 (Raf-1 Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways are G-protein signaling_K-RAS regulation pathway and CD209 (DC-SIGN) signaling. Affiliated tissues include brain, brain and testes, and related mouse phenotypes are tumorigenesis and respiratory system.

Related Diseases for Murray Valley Encephalitis

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Diseases related to Murray Valley Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idRelated DiseaseScoreTop Affiliating Genes
1encephalitis11.5
2japanese encephalitis10.8
3west nile virus10.6
4st. louis encephalitis10.5
5louping ill10.4
6yellow fever10.4
7herpes simplex10.4
8poliomyelitis10.4
9herpes simplex encephalitis10.4
10labium majus cancer10.3CD40LG, RAF1
11lung benign neoplasm10.3KRAS, RAF1
12post-traumatic stress disorder10.3CD40LG, F9
1346 xx gonadal dysgenesis10.2CD40LG, IL2
14vaginal yolk sac tumor10.2F9, KRAS
15cholesterol ester storage disease10.2CD40LG, KRAS
16punctate acrokeratoderma freckle like pigmentation10.2KRAS, RAF1
17limbic encephalitis with ncmags antibodies10.2IL2, IL3
18premature ejaculation10.2CD40LG, MICE
19munchausen by proxy10.2CD40LG, MICE
20atopic dermatitis10.1CD40LG, MICE
21excessive tearing10.1CD40LG, IL2, KRAS
22hypersensitivity vasculitis10.1CD40LG, IL2, KRAS
23hematocele of tunica vaginalis testis10.1CD40LG, MICE
24inhibited male orgasm10.1CD40LG, MICE
25central pontine myelinolysis10.1CD40LG, F9, IL2
26tauopathy10.1CD40LG, MICE
27kidney hemangiopericytoma10.1KRAS, MICE
28brain glioblastoma multiforme10.1IL2, IL3
29epidermolysis bullosa10.1CD40LG, MICE
30malignant ependymoma10.1F9, KRAS
31lambert-eaton myasthenic syndrome10.1CD40LG, MICE
32deep corneal vascularisation10.1CD40LG, MICE
33middle ear adenocarcinoma10.1F9, MICE
34extrapyramidal and movement disease10.1CD40LG, MICE
35morgagni cataract10.1CD40LG, MICE
36transient cerebral ischemia10.1CD40LG, MICE
37mononeuritis multiplex10.1CD40LG, MICE
38respiratory system disease10.1KRAS, MICE, RAF1
39viral meningitis10.1CD40LG, ERVW-1, IL2
40uremic neuropathy10.1CD40LG, IL2, THY1
41orthostatic proteinuria10.0CD40LG, F9, MICE
42migraine with aura10.0CD40LG, MICE
43colitis10.0CD40LG, IL2, MICE
44common bile duct disease10.0CD40LG, IL2, MICE
45paratesticular lipoma10.0CD40LG, IL2, MICE
46primary systemic mycosis10.0CD40LG, IL2, MICE
47thyroid lymphoma10.0CD40LG, ERVW-1, MICE
48lymphoma, non-hodgkin10.0CD40LG, IL2, IL3
49bacterial exanthem10.0CD40LG, MICE
50prion disease with protracted course9.9MICE, PRNP, THY1

Graphical network of the top 20 diseases related to Murray Valley Encephalitis:



Diseases related to murray valley encephalitis

Symptoms for Murray Valley Encephalitis

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Symptoms:

 10 (show all 8)
  • fever
  • headache
  • nausea
  • vomiting
  • drowsiness
  • confusion
  • fitting
  • weakness

Drugs & Therapeutics for Murray Valley Encephalitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Murray Valley Encephalitis

Genetic Tests for Murray Valley Encephalitis

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Anatomical Context for Murray Valley Encephalitis

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MalaCards organs/tissues related to Murray Valley Encephalitis:

33
Brain, Testes, Neutrophil, B cells, Kidney

FMA organs/tissues related to Murray Valley Encephalitis:

16
Brain

Animal Models for Murray Valley Encephalitis or affiliated genes

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MGI Mouse Phenotypes related to Murray Valley Encephalitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.4IL2, IL3, KRAS, RAF1, STAB2
2MP:00053887.6IL2, IL3, KRAS, RAF1, STAB2, THY1

Publications for Murray Valley Encephalitis

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Articles related to Murray Valley Encephalitis:

(show top 50)    (show all 169)
idTitleAuthorsYear
1
A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides. (24333681)
2013
2
Murray Valley encephalitis: a review of clinical features, diagnosis and treatment. (22432670)
2012
3
Solid-phase synthesis and screening of a library of C-terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease. (22991186)
2012
4
Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. (22379060)
2012
5
Opportunistic serological surveillance for Murray Valley encephalitis virus in Victoria, February-May 2011. (22860790)
2012
6
Biochemical characterisation of Murray Valley encephalitis virus proteinase. (20621842)
2010
7
Live chimeric and inactivated Japanese encephalitis virus vaccines differ in their cross-protective values against Murray Valley encephalitis virus. (19109382)
2009
8
Structure of the Murray Valley encephalitis virus RNA helicase at 1.9 Angstrom resolution. (17893366)
2007
9
Murray Valley encephalitis in an adult traveller complicated by long-term flaccid paralysis: case report and review of the literature. (17161855)
2007
10
MR findings in Murray Valley encephalitis. (12917132)
2003
11
Polymerase chain reaction tests for the identification of Ross River, Kunjin and Murray Valley encephalitis virus infections in horses. (15084017)
2003
12
Clinical and laboratory findings on the first imported case of Murray Valley encephalitis in Europe. (12856229)
2003
13
Mechanism of virulence attenuation of glycosaminoglycan-binding variants of Japanese encephalitis virus and Murray Valley encephalitis virus. (11967307)
2002
14
Murray Valley encephalitis (Australian encephalitis): FactSheet. (12105611)
2001
15
Murray Valley encephalitis virus surveillance and control initiatives in Australia. National Arbovirus Advisory Committee of the Communicable Diseases Network Australia. (11432524)
2001
16
Murray Valley encephalitis in Western Australia in 2000, with evidence of southerly spread. (11225378)
2000
17
Early diagnosis of Murray Valley encephalitis by reverse transcriptase-polymerase chain reaction. (10740807)
2000
18
The severity of murray valley encephalitis in mice is linked to neutrophil infiltration and inducible nitric oxide synthase activity in the central nervous system. (10482632)
1999
19
DNA-based and alphavirus-vectored immunisation with prM and E proteins elicits long-lived and protective immunity against the flavivirus, Murray Valley encephalitis virus. (9770429)
1998
20
Molecular characterization of virus-specific RNA produced in the brains of flavivirus-susceptible and -resistant mice after challenge with Murray Valley encephalitis virus. (9010281)
1997
21
Protective immune responses to the E and NS1 proteins of Murray Valley encephalitis virus in hybrids of flavivirus-resistant mice. (8683218)
1996
22
Murray valley encephalitis virus envelope protein antigenic variants with altered hemagglutination properties and reduced neuroinvasiveness in mice. (7645203)
1995
23
A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes. (1383567)
1992
24
The Murray Valley encephalitis virus prM protein confers acid resistance to virus particles and alters the expression of epitopes within the R2 domain of E glycoprotein. (1280384)
1992
25
Epitope analysis of the envelope and non-structural glycoproteins of Murray Valley encephalitis virus. (1703213)
1990
26
Synthetic peptides derived from the deduced amino acid sequence of the E-glycoprotein of Murray Valley encephalitis virus elicit antiviral antibody. (2472704)
1989
27
Isolation of Murray Valley encephalitis and Ross River viruses from Aedes normanensis (Diptera: Culicidae) in Western Australia. (2540334)
1989
28
Genetic variation of Murray Valley encephalitis virus. (2841405)
1988
29
A method for predicting Murray Valley encephalitis in southeast Australia using the Southern Oscillation. (3036054)
1986
30
Experimental infection with Murray Valley encephalitis virus: galahs, sulphur-crested cockatoos, corellas, black ducks and wild mice. (3004402)
1985
31
Transovarial transmission of Murray Valley encephalitis virus by Aedes aegypti (L). (6263238)
1980
32
Quantitative studies of the vector competence of Aedes aegypti, Culex annulirostris and other mosquitoes (Diptera: Culicidae) with Murray Valley encephalitis and other Queensland arboviruses. (42801)
1979
33
Serological evidence of inter-epidemic infection of feral pigs in New South Wales with Murray Valley encephalitis virus. (1016127)
1976
34
The proteins of Murray Valley encephalitis virus. (806663)
1975
35
Letter: Murray Valley encephalitis virus in Eastern Australia, 1971. (4758166)
1973
36
Intratypic antigenic variation among strains of the group B arboviruses Murray Valley encephalitis and Kunjin. (4997354)
1971
37
A fatal case of Murray Valley encephalitis. (5430492)
1970
38
Studies of the morphology of Murray Valley encephalitis and Japanese encephalitis viruses growing in cultured mosquito cells. (5651024)
1968
39
A plaque assay method for Murray Valley encephalitis virus. (13965581)
1963
40
Antibody to Murray valley encephalitis and louping-ill viruses in Austrlia and Pauua-New Guinea. (13683282)
1961
41
The action of phospholipase A and lipid solvents on Murray Valley encephalitis virus. (13683281)
1961
42
Murray Valley encephalitis in Papua and New Guinea. II. Serological survey, 1956-1957. (13683283)
1960
43
Studies of arthropod-borne virus infections in Queensland. II. Serological investigations of antibodies to dengue and Murray Valley encephalitis in Eastern Queensland. (13723470)
1960
44
Some aspects of the reaction between crude Murray Valley encephalitis (MVE) virus and deoxycholate. (13669348)
1959
45
Murray Valley encephalitis and Australian X disease. (13221810)
1954
46
The absence of Murray Valley encephalitis virus from the Murray Valley, 1952-1953. (13132162)
1954
47
Murray Valley encephalitis; clinical aspects. (14909903)
1952
48
Murray Valley encephalitis; pathological aspects. (14909904)
1952
49
Murray Valley encephalitis infection in the laboratory mouse. II. Multiplication of virus inoculated intramuscularly. (12997454)
1952
50
Murray Valley encephalitis. (14913606)
1951

Variations for Murray Valley Encephalitis

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Expression for genes affiliated with Murray Valley Encephalitis

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Search GEO for disease gene expression data for Murray Valley Encephalitis.

Pathways for genes affiliated with Murray Valley Encephalitis

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GO Terms for genes affiliated with Murray Valley Encephalitis

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Biological processes related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of tyrosine phosphorylation of Stat5 proteinGO:004252310.4IL2, IL3
2negative regulation of T cell receptor signaling pathwayGO:005086010.3PRNP, THY1
3positive regulation of protein phosphorylationGO:000193410.0IL2, KRAS, RAF1
4MAPK cascadeGO:00001659.5IL2, IL3, KRAS, RAF1
5activation of MAPKK activityGO:00001869.5IL2, IL3, KRAS, RAF1
6Ras protein signal transductionGO:00072659.5IL2, IL3, KRAS, RAF1
7insulin receptor signaling pathwayGO:00082869.5IL2, IL3, KRAS, RAF1
8fibroblast growth factor receptor signaling pathwayGO:00085439.5IL2, IL3, KRAS, RAF1
9Fc-epsilon receptor signaling pathwayGO:00380959.4IL2, IL3, KRAS, RAF1
10neurotrophin TRK receptor signaling pathwayGO:00480119.4IL2, IL3, KRAS, RAF1
11vascular endothelial growth factor receptor signaling pathwayGO:00480109.2IL2, IL3, KRAS, RAF1
12epidermal growth factor receptor signaling pathwayGO:00071739.1IL2, IL3, KRAS, RAF1
13axon guidanceGO:00074118.6IL2, IL3, KRAS, PRNP, RAF1

Molecular functions related to Murray Valley Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051259.5CD40LG, IL2, IL3

Sources for Murray Valley Encephalitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet