DBMD
MCID: MSC011
MIFTS: 19

Muscular Dystrophy, Duchenne and Becker Types (DBMD) malady

Neuronal, Muscle categories

Summaries for Muscular Dystrophy, Duchenne and Becker Types

Sources:
21Genetics Home Reference, 33MalaCards
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Genetics Home Reference:21 Muscular dystrophies are a group of genetic conditions characterized by progressive muscle weakness and wasting (atrophy). The Duchenne and Becker types of muscular dystrophy are two related conditions that primarily affect skeletal muscles, which are used for movement, and heart (cardiac) muscle. These forms of muscular dystrophy occur almost exclusively in males.

MalaCards: Muscular Dystrophy, Duchenne and Becker Types, also known as duchenne and becker muscular dystrophy, is related to becker muscular dystrophy and duchenne muscular dystrophy, and has symptoms including scoliosis, intellectual deficit/mental/psychomotor retardation/learning disability and abnormal gait. An important gene associated with Muscular Dystrophy, Duchenne and Becker Types is DMD (dystrophin). Affiliated tissues include heart and skeletal muscle.

Aliases & Classifications for Muscular Dystrophy, Duchenne and Becker Types

Sources:
64Wikipedia, 21Genetics Home Reference, 49Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal, Muscle


Characteristics (Orphanet epidemiological data):

49
duchenne and becker muscular dystrophy:
Inheritance: X-linked recessive; Prevalence: 1-9/100000; Age of onset: Childhood; Age of death: Young adult


Aliases & Descriptions:

muscular dystrophy, duchenne and becker types 64 21
duchenne and becker muscular dystrophy 21 49
duchenne/becker muscular dystrophy 64 21
dbmd 64 21
severe dystrophinopathy, duchenne and becker type 49
muscular dystrophy, duchenne and becker type 64
muscular dystrophy, pseudohypertrophic 21


External Ids:

ICD10 via Orphanet26 G71.0

Related Diseases for Muscular Dystrophy, Duchenne and Becker Types

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17GeneCards, 18GeneDecks
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Diseases related to Muscular Dystrophy, Duchenne and Becker Types via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1becker muscular dystrophy11.4
2duchenne muscular dystrophy11.4
3muscular atrophy10.5
4spinal muscular atrophy10.5
5fatty liver disease10.4
6ocular muscular dystrophy10.4
7left ventricular noncompaction10.4
8nondystrophic myotonia10.4
9myotonia10.4
10pulmonary function10.4
11dystrophinopathies10.0

Graphical network of diseases related to Muscular Dystrophy, Duchenne and Becker Types:



Diseases related to muscular dystrophy, duchenne and becker types

Clinical Features for Muscular Dystrophy, Duchenne and Becker Types

Sources:
49Orphanet
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Symptoms:

49 (show all 14)
  • scoliosis
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • abnormal gait
  • lordosis
  • psychic/psychomotor regression/dementia/intellectual decline
  • osteoporosis/osteopenia/demineralisation/osteomalacia/rickets
  • restricted joint mobility/joint stiffness/ankylosis
  • myopathy
  • muscle hypotrophy/atrophy/dystrophy/agenesis/amyotrophy
  • cardiomyopathy/hypertrophic/dilated
  • abnormal muscle biopsy/muscle enzymes/cpk/ldh/aldolase/creatin phosphokinase
  • abnormal emg/electromyogram/electropmyography
  • x-linked recessive inheritance
  • narrowed/gracile diaphysis/diaphyses/long bones/dolichostenomelia

Drugs & Therapeutics for Muscular Dystrophy, Duchenne and Becker Types

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Muscular Dystrophy, Duchenne and Becker Types

Anatomical Context for Muscular Dystrophy, Duchenne and Becker Types

Sources:
33MalaCards
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MalaCards organs/tissues related to Muscular Dystrophy, Duchenne and Becker Types:

33
Heart, Skeletal muscle

Animal Models for Muscular Dystrophy, Duchenne and Becker Types or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Muscular Dystrophy, Duchenne and Becker Types

Genetic Variations for Muscular Dystrophy, Duchenne and Becker Types

Expression for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

Search GEO for disease gene expression data for Muscular Dystrophy, Duchenne and Becker Types.

Pathways for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

Compounds for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

GO Terms for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

Products for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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  • Lysates
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Sources for Muscular Dystrophy, Duchenne and Becker Types

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet