DBMD
MCID: MSC011
MIFTS: 24

Muscular Dystrophy, Duchenne and Becker Types (DBMD) malady

Neuronal diseases, Muscle diseases categories

Summaries for Muscular Dystrophy, Duchenne and Becker Types

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21Genetics Home Reference, 32MalaCards
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Genetics Home Reference:21 Muscular dystrophies are a group of genetic conditions characterized by progressive muscle weakness and wasting (atrophy). The Duchenne and Becker types of muscular dystrophy are two related conditions that primarily affect skeletal muscles, which are used for movement, and heart (cardiac) muscle. These forms of muscular dystrophy occur almost exclusively in males.

MalaCards: Muscular Dystrophy, Duchenne and Becker Types, also known as duchenne and becker muscular dystrophy, is related to becker muscular dystrophy and duchenne muscular dystrophy, and has symptoms including narrowed/gracile diaphysis/diaphyses/long bones/dolichostenomelia, x-linked recessive inheritance and abnormal emg/electromyogram/electropmyography. An important gene associated with Muscular Dystrophy, Duchenne and Becker Types is DMD (dystrophin). Affiliated tissues include skeletal muscle, heart and bone.

Aliases & Classifications for Muscular Dystrophy, Duchenne and Becker Types

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63Wikipedia, 21Genetics Home Reference, 48Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Muscle diseases


Characteristics (Orphanet epidemiological data):

48
duchenne and becker muscular dystrophy:
Inheritance: X-linked recessive; Prevalence: 1-9/100000; Age of onset: Childhood; Age of death: Young adult


Aliases & Descriptions:

muscular dystrophy, duchenne and becker types 63 21
duchenne and becker muscular dystrophy 21 48
duchenne/becker muscular dystrophy 63 21
dbmd 63 21
severe dystrophinopathy, duchenne and becker type 48
muscular dystrophy, duchenne and becker type 63
muscular dystrophy, pseudohypertrophic 21


External Ids:

ICD10 via Orphanet26 G71.0

Related Diseases for Muscular Dystrophy, Duchenne and Becker Types

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17GeneCards, 18GeneDecks
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Diseases related to Muscular Dystrophy, Duchenne and Becker Types via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1becker muscular dystrophy11.4
2duchenne muscular dystrophy11.4
3muscular dystrophy11.4
4muscular atrophy10.5
5spinal muscular atrophy10.5
6fatty liver disease10.4
7dilated cardiomyopathy10.4
8ischemia10.4
9liver disease10.4
10myositis10.4
11myotonic disease10.4
12neuromuscular disease10.4
13myotonic dystrophy type 110.4
14dystrophinopathies10.0

Graphical network of diseases related to Muscular Dystrophy, Duchenne and Becker Types:



Diseases related to muscular dystrophy, duchenne and becker types

Clinical Features for Muscular Dystrophy, Duchenne and Becker Types

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48Orphanet
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Symptoms:

48 (show all 14)
  • narrowed/gracile diaphysis/diaphyses/long bones/dolichostenomelia
  • x-linked recessive inheritance
  • abnormal emg/electromyogram/electropmyography
  • abnormal muscle biopsy/muscle enzymes/cpk/ldh/aldolase/creatin phosphokinase
  • cardiomyopathy/hypertrophic/dilated
  • muscle hypotrophy/atrophy/dystrophy/agenesis/amyotrophy
  • myopathy
  • restricted joint mobility/joint stiffness/ankylosis
  • osteoporosis/osteopenia/demineralisation/osteomalacia/rickets
  • psychic/psychomotor regression/dementia/intellectual decline
  • lordosis
  • abnormal gait
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • scoliosis

Drugs & Therapeutics for Muscular Dystrophy, Duchenne and Becker Types

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Muscular Dystrophy, Duchenne and Becker Types

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Anatomical Context for Muscular Dystrophy, Duchenne and Becker Types

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32MalaCards
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MalaCards organs/tissues related to Muscular Dystrophy, Duchenne and Becker Types:

32
Skeletal muscle, Heart, Bone

Animal Models for Muscular Dystrophy, Duchenne and Becker Types or affiliated genes

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Publications for Muscular Dystrophy, Duchenne and Becker Types

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50PubMed
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Articles related to Muscular Dystrophy, Duchenne and Becker Types:

idTitleAuthorsYear
1
Prenatal molecular diagnosis of inherited neuromuscular diseases: Duchenne/Becker muscular dystrophy, myotonic dystrophy type 1 and spinal muscular atrophy. (23729582)
2013

Genetic Variations for Muscular Dystrophy, Duchenne and Becker Types

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Expression for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

Search GEO for disease gene expression data for Muscular Dystrophy, Duchenne and Becker Types.

Pathways for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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Compounds for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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GO Terms for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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Products for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Muscular Dystrophy, Duchenne and Becker Types

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet