DBMD
MCID: MSC011
MIFTS: 21

Muscular Dystrophy, Duchenne and Becker Types (DBMD) malady

Neuronal diseases, Rare diseases, Muscle diseases categories

Summaries for Muscular Dystrophy, Duchenne and Becker Types

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22Genetics Home Reference, 34MalaCards
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Genetics Home Reference:22 Muscular dystrophies are a group of genetic conditions characterized by progressive muscle weakness and wasting (atrophy). The Duchenne and Becker types of muscular dystrophy are two related conditions that primarily affect skeletal muscles, which are used for movement, and heart (cardiac) muscle. These forms of muscular dystrophy occur almost exclusively in males.

MalaCards: Muscular Dystrophy, Duchenne and Becker Types, also known as duchenne and becker muscular dystrophy, is related to becker muscular dystrophy and muscular dystrophy, and has symptoms including psychic/psychomotor regression/dementia/intellectual decline, intellectual deficit/mental/psychomotor retardation/learning disability and restricted joint mobility/joint stiffness/ankylosis. An important gene associated with Muscular Dystrophy, Duchenne and Becker Types is DMD (dystrophin). Affiliated tissues include bone.

Aliases & Classifications for Muscular Dystrophy, Duchenne and Becker Types

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66Wikipedia, 22Genetics Home Reference, 50Orphanet, 27ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases, Muscle diseases


Characteristics (Orphanet epidemiological data):

50
duchenne and becker muscular dystrophy:
Inheritance: X-linked recessive; Prevalence: 1-9/100000; Age of onset: Childhood; Age of death: Young adult


Aliases & Descriptions:

muscular dystrophy, duchenne and becker types 66 22
duchenne and becker muscular dystrophy 22 50
duchenne/becker muscular dystrophy 66 22
dbmd 66 22
severe dystrophinopathy, duchenne and becker type 50
muscular dystrophy, duchenne and becker type 66
muscular dystrophy, pseudohypertrophic 22


External Ids:

ICD10 via Orphanet27 G71.0

Related Diseases for Muscular Dystrophy, Duchenne and Becker Types

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18GeneCards, 19GeneDecks
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Diseases related to Muscular Dystrophy, Duchenne and Becker Types via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1becker muscular dystrophy11.4
2muscular dystrophy11.4
3muscular atrophy10.5
4spinal muscular atrophy10.5
5fatty liver disease10.4
6dilated cardiomyopathy10.4
7ischemia10.4
8liver disease10.4
9duchenne muscular dystrophy10.4
10myositis10.4
11myotonic dystrophy10.4
12neuromuscular disease10.4
13myotonic dystrophy type 110.4
14left ventricular noncompaction10.4
15nondystrophic myotonia10.4
16myotonia10.4
17pulmonary function10.4
18dystrophinopathies10.1

Graphical network of diseases related to Muscular Dystrophy, Duchenne and Becker Types:



Diseases related to muscular dystrophy, duchenne and becker types

Symptoms for Muscular Dystrophy, Duchenne and Becker Types

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50Orphanet
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Symptoms:

50 (show all 14)
  • psychic/psychomotor regression/dementia/intellectual decline
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • restricted joint mobility/joint stiffness/ankylosis
  • narrowed/gracile diaphysis/diaphyses/long bones/dolichostenomelia
  • osteoporosis/osteopenia/demineralisation/osteomalacia/rickets
  • cardiomyopathy/hypertrophic/dilated
  • scoliosis
  • lordosis
  • x-linked recessive inheritance
  • abnormal emg/electromyogram/electropmyography
  • abnormal muscle biopsy/muscle enzymes/cpk/ldh/aldolase/creatin phosphokinase
  • muscle hypotrophy/atrophy/dystrophy/agenesis/amyotrophy
  • myopathy
  • abnormal gait

Drugs & Therapeutics for Muscular Dystrophy, Duchenne and Becker Types

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Muscular Dystrophy, Duchenne and Becker Types

Drug clinical trials:

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Genetic Tests for Muscular Dystrophy, Duchenne and Becker Types

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Anatomical Context for Muscular Dystrophy, Duchenne and Becker Types

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34MalaCards
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MalaCards organs/tissues related to Muscular Dystrophy, Duchenne and Becker Types:

34
Bone

Animal Models for Muscular Dystrophy, Duchenne and Becker Types or affiliated genes

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Publications for Muscular Dystrophy, Duchenne and Becker Types

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Variations for Muscular Dystrophy, Duchenne and Becker Types

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Expression for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

Search GEO for disease gene expression data for Muscular Dystrophy, Duchenne and Becker Types.

Pathways for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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Compounds for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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GO Terms for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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Products for genes affiliated with Muscular Dystrophy, Duchenne and Becker Types

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Muscular Dystrophy, Duchenne and Becker Types

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet