MCID: MTG002
MIFTS: 40

Mutagen Sensitivity malady

Rare diseases category

Aliases & Classifications for Mutagen Sensitivity

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Aliases & Descriptions for Mutagen Sensitivity:

Name: Mutagen Sensitivity 42


Classifications:



Summaries for Mutagen Sensitivity

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MalaCards based summary: Mutagen Sensitivity is related to lung cancer and breast cancer. An important gene associated with Mutagen Sensitivity is BLMH (bleomycin hydrolase), and among its related pathways are Platinum Pathway, Pharmacokinetics/Pharmacodynamics and Naphthalene metabolism. The compounds drugs for treatment of tuberculosis and vinylchloride have been mentioned in the context of this disorder. Affiliated tissues include lung, breast and skin, and related mouse phenotypes are pigmentation and vision/eye.

Related Diseases for Mutagen Sensitivity

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Diseases related to Mutagen Sensitivity via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 91)
idRelated DiseaseScoreTop Affiliating Genes
1lung cancer31.0TP53, DNMT1, GSTM1
2breast cancer31.0TP53, BRCA1
3oral cancer30.6TP53, GSTM1, GSTT1
4endometriosis30.5GSTT1, GSTM1, NAT2
5melanoma29.7TP53, BRCA2, XRCC1, XRCC3, DNMT1, GSTT1
6nasopharyngeal carcinoma29.6TP53, NAT2, XRCC1, DNMT3B, DNMT1, GSTM1
7ataxia-telangiectasia29.5DNMT1, XRCC3, XRCC1, BRCA1, BRCA2, TP53
8hepatocellular carcinoma29.2TP53, BRCA2, NAT2, DNMT3B, DNMT1, GSTM1
9colorectal cancer28.1DNMT3B, DNMT1, GSTM1, GSTT1, XRCC1, NAT2
10hereditary breast ovarian cancer10.4BRCA2
11brain cancer10.4GSTM1, GSTT1
12asbestosis10.4GSTM1, GSTT1
13trichothiodystrophy10.4XPA, ERCC2
14senile cataract10.4GSTM1, GSTT1
15mismatch repair cancer syndrome10.4GSTM1, GSTT1
16immunodeficiency, centromere instability and facial anomalies syndrome10.3DNMT3B, DNMT1
17open-angle glaucoma10.3GSTM1, GSTT1
18acute myeloid leukemia, adult10.3GSTM1, GSTT1
19leukoplakia10.3GSTM1, GSTT1
20acute lymphoblastic leukemia, childhood10.3XRCC1, GSTM1, GSTT1
21skin benign neoplasm10.3XPC, XPA, ERCC2
22nasopharyngitis10.3
23brca1 and brca2 hereditary breast and ovarian cancer10.2BRCA2, BRCA1
24fallopian tube cancer10.2BRCA2, BRCA1
25peritoneal carcinoma10.2BRCA2, BRCA1
26bilateral breast cancer10.2BRCA2, BRCA1
27gastric adenocarcinoma10.2NAT2, GSTM1, GSTT1
28pulmonary disease, chronic obstructive10.2GSTT1, GSTM1, NAT2
29lynch syndrome10.2BRCA2, BRCA1
30dysgerminoma10.2BRCA1, BRCA2
31cockayne syndrome10.2XPC, XPA, RAD23B, ERCC2
32cowden disease10.2BRCA2, BRCA1
33oligodendroglioma10.2TP53, GSTT1, ERCC2
34laryngeal carcinoma10.2TP53, NAT2, GSTT1
35alcoholic liver cirrhosis10.2NAT2, GSTM1
36thyroid cancer10.2TP53, GSTM1, GSTT1
37gynecomastia10.1BRCA1, BRCA2
38alzheimer disease10.1GSTT1, GSTM1, NAT2, BLMH
39myelodysplastic syndrome10.1DNMT3B, DNMT1, GSTM1, GSTT1
40sporadic breast cancer10.1
41sarcoma10.1
42soft tissue sarcoma10.1
43ataxia10.1
44cytomegalovirus infection10.1
45acute leukemia10.1GSTT1, GSTM1, DNMT1, DNMT3B
46breast ductal carcinoma10.1TP53, BRCA1
47lymphoma, non-hodgkin10.1NAT2, GSTM1, GSTT1, ERCC2
48cervical cancer, somatic10.1TP53, XRCC1, GSTM1, GSTT1
49fanconi anemia, complementation group a10.1ERCC2, BRCA1, BRCA2
50nicotine dependence, protection against10.1NAT2, XRCC1, XRCC3, GSTM1, GSTT1

Graphical network of the top 20 diseases related to Mutagen Sensitivity:



Diseases related to mutagen sensitivity

Symptoms for Mutagen Sensitivity

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Drugs & Therapeutics for Mutagen Sensitivity

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Drug clinical trials:

Search ClinicalTrials for Mutagen Sensitivity

Search NIH Clinical Center for Mutagen Sensitivity

Genetic Tests for Mutagen Sensitivity

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Anatomical Context for Mutagen Sensitivity

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MalaCards organs/tissues related to Mutagen Sensitivity:

31
Lung, Breast, Skin, Testes, Colon

Animal Models for Mutagen Sensitivity or affiliated genes

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MGI Mouse Phenotypes related to Mutagen Sensitivity:

35 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011868.7ERCC2, XPA, DNMT1, BRCA1, TP53
2MP:00053918.5XPC, ERCC2, RAD23B, XPA, TP53, DNMT3B
3MP:00053717.8BRCA2, BRCA1, BLMH, XPA, TP53, IGF1
4MP:00053807.8XRCC1, DNMT3B, RAD23B, BRCA1, BRCA2, TP53
5MP:00053757.4ERCC2, IGF1, TP53, BRCA1, RAD23B, XPA
6MP:00053907.4TP53, IGF1, BRCA2, BRCA1, DNMT3B, XPA
7MP:00028736.9DNMT1, XRCC1, BRCA1, BRCA2, RAD23B, TP53
8MP:00053796.8IGFBP3, BRCA2, IGF1, ERCC2, RAD23B, XPA
9MP:00053976.8ERCC2, DNMT3B, DNMT1, XPA, BRCA2, BRCA1
10MP:00020066.7TP53, BRCA2, XRCC1, IGF1, DNMT3B, DNMT1
11MP:00107716.7XPA, IGF1, BLMH, TP53, BRCA1, DNMT1
12MP:00053876.6BRCA2, IGF1, BLMH, TP53, BRCA1, DNMT3B
13MP:00053896.5XPA, IGF1, RAD23B, ERCC2, DNMT1, DNMT3B
14MP:00053866.3BRCA1, ERCC2, RAD23B, XPA, XPC, IGFBP3
15MP:00036316.3IGF1, XPA, XPC, GSTM1, DNMT1, XRCC1
16MP:00107686.1XPC, DNMT3B, XPA, RAD23B, XRCC1, BRCA2
17MP:00053846.0ERCC2, XPC, RAD23B, XPA, IGF1, TP53
18MP:00053785.6DNMT1, XPC, RAD23B, XPA, ERCC2, DNMT3B
19MP:00053765.3XPC, XPA, RAD23B, ERCC2, IGF1, IGFBP3

Publications for Mutagen Sensitivity

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Articles related to Mutagen Sensitivity:

(show top 50)    (show all 121)
idTitleAuthorsYear
1
4-Nitroquinoline-1-oxide-induced mutagen sensitivity and risk of cutaneous melanoma: a case-control analysis. (24977319)
2014
2
Mutagen sensitivity as measured by induced chromatid breakage as a marker of cancer risk. (24623229)
2014
3
Bleomycin-induced mutagen sensitivity, passive smoking, and risk of breast cancer in Chinese women: a case-control study. (23371556)
2013
4
Gamma-ray-induced mutagen sensitivity and risk of sporadic breast cancer in young women: a case-control study. (22218884)
2012
5
Evaluating the effects of genetic variants of DNA repair genes using cytogenetic mutagen sensitivity approaches. (21595606)
2011
6
Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure. (21164199)
2011
7
Mutagen sensitivity in oral cancer patients, healthy tobacco chewers and controls. (20391973)
2010
8
Mutagen sensitivity and DNA repair of the EGFR gene in oropharyngeal cancer. (20400363)
2010
9
Mutagen sensitivity, tobacco smoking and breast cancer risk: a case-control study. (20110285)
2010
10
Chromosomal alterations and mutagen sensitivity in human mucosal cells of the oropharynx and lymphocytes caused by BPDE. (19996129)
2009
11
Haplotypes of DNMT1 and DNMT3B are associated with mutagen sensitivity induced by benzo[a]pyrene diol epoxide among smokers. (18499700)
2008
12
Mutagen sensitivity: a genetic predisposition factor for cancer. (17440053)
2007
13
Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. (17932354)
2007
14
Mutagen sensitivity has high heritability: evidence from a twin study. (16778168)
2006
15
Mutagen sensitivity and neoplastic progression in patients with Barrett's esophagus: a prospective analysis. (17035402)
2006
16
gamma-Radiation-induced chromosomal mutagen sensitivity is associated with breast cancer risk in African-American women: caffeine modulates the outcome of mutagen sensitivity assay. (16537698)
2006
17
High mutagen sensitivity in peripheral blood lymphocytes predicts poor overall and disease-specific survival in patients with stage III non-small cell lung cancer treated with radiotherapy and chemotherapy. (15837739)
2005
18
Mutagen sensitivity of patients with cancer at different sites of the head and neck. (16105906)
2005
19
Differential mutagen sensitivity of peripheral blood lymphocytes from smokers and nonsmokers: effect of human cytomegalovirus infection. (15065204)
2004
20
Inter-rater agreement on chromosome 5 breakage in FISH-based mutagen sensitivity assays (MSAs). (15279836)
2004
21
Aphidicolin and bleomycin induced chromosome damage as biomarker of mutagen sensitivity: a twin study. (14757193)
2004
22
Chromosomal mutagen sensitivity associated with mutations in BRCA genes. (15162060)
2004
23
Mutagen sensitivity of human lymphoblastoid cells with a BRCA1 mutation. (12611459)
2003
24
Mutagen sensitivity as a susceptibility marker for endometriosis. (14507820)
2003
25
Construction of green fluorescent protein reporter genes for genotoxicity test (SOS/umu-test) and improvement of mutagen-sensitivity. (16233101)
2001
26
Joint effect of insulin-like growth factors and mutagen sensitivity in lung cancer risk. (10984281)
2000
27
Mutagen sensitivity in patients with familial and non-familial urothelial cell carcinoma. (11054683)
2000
28
Mutagen sensitivity as a biomarker for second primary tumors after head and neck squamous cell carcinoma. (10919742)
2000
29
Family history of cancer, mutagen sensitivity, and increased risk of head and neck cancer. (10656614)
1999
30
Genetics of smoking-related cancer and mutagen sensitivity. (10393708)
1999
31
Mutagen sensitivity to benzo(a)pyrene diol epoxide and the risk of squamous cell carcinoma of the head and neck. (9676854)
1998
32
Increased mutagen sensitivity in patients with head and neck cancer is less pronounced in patients with nasopharyngeal carcinoma. (9604986)
1998
33
A statistical analysis of the reliability and classification error in application of the mutagen sensitivity assay. (8833619)
1996
34
Mutagen sensitivity as a predisposing factor in familial oral cancer. (8797865)
1996
35
Mutagen sensitivity: enhanced risk assessment of squamous cell carcinoma. (9039218)
1996
36
Mutagen sensitivity and risk of gliomas: a case-control analysis. (8603389)
1996
37
Correlations between mutagen sensitivity and plasma nutrient levels of healthy individuals. (7541679)
1995
38
A case-control study of wood dust exposure, mutagen sensitivity, and lung cancer risk. (8547823)
1995
39
Evidence of a chromatin basis for increased mutagen sensitivity associated with multiple primary malignancies of the head and neck. (7539412)
1995
40
Mutagen sensitivity as a biological marker of lung cancer risk in African Americans. (7537995)
1995
41
Lung cancer, smoking patterns, and mutagen sensitivity in Mexican-Americans. (8562219)
1995
42
Mutagen sensitivity and suppression of position-effect variegation result from mutations in mus209, the Drosophila gene encoding PCNA. (7907981)
1994
43
Mitotic catastrophe is the mechanism of lethality for mutations that confer mutagen sensitivity in Aspergillus nidulans. (7506362)
1994
44
Association between family history of cancer and mutagen sensitivity in upper aerodigestive tract cancer patients. (7682127)
1993
45
Increased mutagen sensitivity in human cultured fibroblasts with constitutively high micronucleus levels. (1551087)
1992
46
Mutagen sensitivity in patients with head and neck cancers: a biologic marker for risk of multiple primary malignancies. (1700135)
1990
47
Epistasis, photoreactivation and mutagen sensitivity of DNA repair mutants upr-1 and mus-26 in Neurospora crassa. (2528064)
1989
48
Mutagen sensitivity and mutability in lentil. (24247709)
1986
49
Biochemical genetics of Neurospora nuclease II: Mutagen sensitivity and other characteristics of the nuclease mutants. (6309614)
1983
50
Mutagen sensitivity of wild type and recombination deficient c(3)G strains of Drosophila melanogaster. (121955)
1978

Variations for Mutagen Sensitivity

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Expression for genes affiliated with Mutagen Sensitivity

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Search GEO for disease gene expression data for Mutagen Sensitivity.

Pathways for genes affiliated with Mutagen Sensitivity

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Pathways related to Mutagen Sensitivity according to GeneCards Suite gene sharing:

(show all 28)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9GSTT1, GSTM1
29.9GSTM1, GSTT1
3
Show member pathways
9.6TP53, ERCC2
4
Show member pathways
9.5GSTM1, NAT2, GSTT1
5
Show member pathways
9.5BRCA2, BRCA1
6
Show member pathways
9.5BRCA1, BRCA2
79.5TP53, BRCA1
89.5BRCA1, TP53
99.5TP53, BRCA1
10
Show member pathways
One Carbon Metabolism36
dTMP de novo biosynthesis (mitochondrial)36
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate36
Trans-sulfuration and one carbon metabolism36
methionine salvage36
Methionine metabolism59
9.5DNMT3B, GSTM1, DNMT1
11
Show member pathways
9.4ERCC2, XRCC3, TP53
12
Show member pathways
9.3ERCC2, RAD23B, XPC, XPA
139.1TP53, XPC, XPA, ERCC2
149.0IGFBP3, IGF1
15
Show member pathways
9.0BRCA1, TP53, BRCA2
168.8TP53, DNMT1, BRCA1, DNMT3B
178.8TP53, BRCA2, XRCC3, BRCA1
188.7XPC, BRCA1, BRCA2, TP53
198.5IGFBP3, IGF1, TP53
20
Show member pathways
Development IGF RI signaling
Immune response IL 4 signaling pathway59
Signal transduction AKT signaling59
8.5IGFBP3, IGF1, TP53
218.5IGFBP3, TP53, IGF1
22
Show member pathways
Signaling Pathways in Glioblastoma36
8.2IGF1, BRCA2, BRCA1, TP53
23
Show member pathways
8.1XPC, RAD23B, XPA, ERCC2, XRCC1, BRCA1
24
Show member pathways
8.1XRCC1, XPC, BRCA1, ERCC2, BRCA2, TP53
25
Show member pathways
DNA damage response36
8.1IGF1, BRCA1, TP53, IGFBP3
267.5TP53, IGF1, IGFBP3, BRCA2, BRCA1
27
Show member pathways
7.3BRCA1, IGF1, ERCC2, RAD23B, XRCC1, TP53

Compounds for genes affiliated with Mutagen Sensitivity

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Compounds related to Mutagen Sensitivity according to GeneCards Suite gene sharing:

(show top 50)    (show all 160)
idCompoundScoreTop Affiliating Genes
1drugs for treatment of tuberculosis509.9NAT2, GSTM1, GSTT1
2vinylchloride449.9GSTT1, GSTM1, XRCC1
3pyrazinamide44 50 1111.6NAT2, GSTM1, GSTT1
4arylamine449.6NAT2, GSTM1, GSTT1
5gsts449.6GSTM1, NAT2, XRCC1, GSTT1
6styrene449.5NAT2, GSTT1, GSTM1
7platinum44 5010.5BRCA1, XRCC1, GSTT1, ERCC2
8benzene449.5XRCC3, GSTM1, GSTT1, XRCC1, NAT2
9epoxide449.5GSTM1, NAT2, GSTT1, XRCC1
10fluorouracil50 1110.4XRCC3, XRCC1, ERCC2, TP53
11aflatoxin b144 2410.4GSTM1, TP53, NAT2, GSTT1
12cotinine44 2410.4XRCC1, GSTM1, GSTT1, ERCC2, NAT2
13bpde449.3TP53, GSTT1, GSTM1, BRCA1
14diepoxybutane449.3XRCC1, GSTM1, GSTT1, BRCA1, NAT2
151-hydroxypyrene449.2NAT2, GSTM1, GSTT1
165-methylcytosine44 2410.2DNMT3B, DNMT1, BRCA1, TP53
17hydrocarbons449.1GSTT1, ERCC2, BRCA1, GSTM1, NAT2
188-oxoguanine449.1GSTM1, BRCA2, GSTT1, XRCC1, BRCA1
19carboplatin44 50 1111.1BRCA1, GSTM1, XRCC1, GSTT1, TP53
20p002449.0BRCA1, BRCA2, XRCC1, GSTM1, GSTT1
21methylmethanesulfonate449.0BRCA2, BRCA1, TP53, XRCC1
22thymidylate448.9GSTM1, ERCC2, XRCC1, TP53, BRCA1
23mitomycin c448.9XRCC3, TP53, BRCA2, BRCA1, XPA
24betacarotene448.8IGFBP3, NAT2, XRCC1, GSTM1
25camptothecin44 60 1110.8TP53, BRCA2, XRCC1, XRCC3, BRCA1
26adpribose448.7DNMT1, XRCC1, BRCA1, BRCA2, TP53
27vincristine44 50 1110.7BRCA1, BRCA2, GSTM1, ERCC2, TP53
28oxaliplatin44 50 1110.5XRCC1, TP53, BRCA1, XPA, GSTM1, ERCC2
29mspi448.5DNMT1, BRCA2, NAT2, XRCC1, GSTM1, GSTT1
30docetaxel44 50 60 1111.4BRCA2, BRCA1, NAT2, TP53, ERCC2, XRCC3
315-aza-2deoxycytidine448.4DNMT1, DNMT3B, IGFBP3, TP53, BRCA1
32lycopene44 249.4IGFBP3, BRCA1, BRCA2, IGF1
33cyclophosphamide44 50 1110.4TP53, NAT2, XRCC1, GSTM1, ERCC2, BRCA1
345fluorouracil448.4BRCA1, GSTM1, XRCC1, IGFBP3, TP53, ERCC2
35p003448.3XRCC1, BRCA1, IGFBP3, BRCA2, XRCC3, GSTM1
36methotrexate50 44 1110.2IGFBP3, BRCA2, NAT2, GSTM1, ERCC2, BRCA1
37proline448.2GSTT1, RAD23B, BRCA1, BRCA2, TP53, DNMT1
38benzo(a)pyrene448.2TP53, NAT2, XRCC1, GSTM1, GSTT1, XPC
39doxorubicin44 50 1110.2GSTM1, BRCA1, TP53, DNMT1, GSTT1, IGFBP3
40adriamycin448.1IGF1, BRCA2, BRCA1, DNMT1, TP53
41bleomycin44 118.8IGF1, BLMH, BRCA2, BRCA1, XRCC1, GSTM1
42glutamine447.7XRCC1, BRCA1, BRCA2, IGF1, IGFBP3, RAD23B
43etoposide44 50 60 1110.4IGFBP3, IGF1, GSTT1, BRCA1, BRCA2, TP53
44oligonucleotide447.3GSTT1, BRCA2, DNMT1, XPC, TP53, XPA
45tamoxifen44 50 28 1110.3DNMT3B, BRCA2, DNMT1, IGF1, IGFBP3, BRCA1
46thymidine44 248.1BRCA1, IGFBP3, DNMT1, BRCA2, TP53, IGF1
47progesterone44 28 60 24 1111.1IGF1, TP53, BRCA2, NAT2, DNMT1, IGFBP3
48folate446.9GSTM1, GSTT1, ERCC2, DNMT1, DNMT3B, XRCC3
49estrogen446.3GSTM1, GSTT1, DNMT1, IGF1, BRCA2, TP53
50cisplatin44 50 60 119.1DNMT1, XRCC3, XRCC1, IGFBP3, TP53, BRCA2

GO Terms for genes affiliated with Mutagen Sensitivity

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Cellular components related to Mutagen Sensitivity according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1XPC complexGO:00719429.8XPC, RAD23B
2replication forkGO:00056579.4TP53, XRCC3, DNMT1
3insulin-like growth factor binding protein complexGO:00169428.7IGFBP3, IGF1
4nucleolusGO:00057308.3RAD23B, XPA, XPC, DNMT3B, BRCA2, TP53
5nucleoplasmGO:00056547.7TP53, BRCA2, BRCA1, XRCC1, XPC, XPA
6cytoplasmGO:00057376.8BLMH, TP53, BRCA2, BRCA1, XRCC3, DNMT3B
7nucleusGO:00056346.0ERCC2, IGFBP3, BLMH, TP53, BRCA2, BRCA1

Biological processes related to Mutagen Sensitivity according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1nucleotide-excision repair, DNA damage recognitionGO:000071510.2XPC, RAD23B
2regulation of mitotic cell cycle phase transitionGO:0190199010.1ERCC2, XPC
3response to organic substanceGO:001003310.0XRCC1, XRCC3
4DNA methylationGO:00063069.9DNMT3B, DNMT1
5glutathione derivative biosynthetic processGO:019016879.8GSTM1, GSTT1
6xenobiotic metabolic processGO:00068059.7GSTM1, NAT2, GSTT1
7positive regulation of cell cycle arrestGO:00711589.7BRCA1, TP53
8negative regulation of histone H3-K9 methylationGO:00515739.7DNMT1, BRCA1, DNMT3B
9positive regulation of histone H3-K4 methylationGO:00515719.7BRCA1, DNMT1, DNMT3B
10nucleotide-excision repair, DNA damage removalGO:00007189.7XPC, ERCC2, RAD23B, XPA
11response to X-rayGO:00101659.6BRCA2, TP53
12double-strand break repair via homologous recombinationGO:00007249.5XRCC3, BRCA1, BRCA2
13response to drugGO:00424939.5XPC, GSTT1, DNMT3B, XRCC1, BLMH
14cell agingGO:00075699.4BRCA2, TP53
15positive regulation of DNA bindingGO:00433889.4ERCC2, IGF1
16cellular response to DNA damage stimulusGO:00069749.3TP53, BRCA1, XRCC3
17DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:00069789.3TP53, BRCA1, BRCA2
18positive regulation of insulin-like growth factor receptor signaling pathwayGO:00435689.3IGF1, IGFBP3
19double-strand break repairGO:00063029.2TP53, BRCA2, BRCA1
20response to gamma radiationGO:00103329.1BRCA2, TP53
21multicellular organism growthGO:00352648.9IGF1, ERCC2, TP53, XPA
22nucleotide-excision repairGO:00062898.6XPA, XPC, BRCA2, TP53, ERCC2, RAD23B
23DNA repairGO:00062818.2ERCC2, XPA, XRCC3, XRCC1, BRCA1, BRCA2
24positive regulation of transcription, DNA-templatedGO:00458938.1IGF1, ERCC2, BRCA1, BRCA2, TP53

Molecular functions related to Mutagen Sensitivity according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glutathione transferase activityGO:00043649.9GSTT1, GSTM1
2DNA-methyltransferase activityGO:00090089.8DNMT3B, DNMT1
3DNA (cytosine-5-)-methyltransferase activityGO:00038869.7DNMT1, DNMT3B
4single-stranded DNA bindingGO:00036979.1RAD23B, XPC, BRCA2
5damaged DNA bindingGO:00036849.0RAD23B, XPA, XPC, XRCC1, TP53
6protein bindingGO:00055155.1BRCA1, BRCA2, TP53, BLMH, IGF1, IGFBP3

Sources for Mutagen Sensitivity

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet