MCID: MYC013
MIFTS: 35

Mycobacterium Abscessus malady

Category: Rare diseases

Aliases & Classifications for Mycobacterium Abscessus

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Aliases & Descriptions for Mycobacterium Abscessus:

Name: Mycobacterium Abscessus 45
Mycobacterium Abscessus Infection 45
 
M. Abscessus 45

Classifications:



Summaries for Mycobacterium Abscessus

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Wikipedia:68 Mycobacterium abscessus is a rapidly growing mycobacterium that is a common water contaminant. It was... more...

MalaCards based summary: Mycobacterium Abscessus, also known as mycobacterium abscessus infection, is related to vulvovaginitis and periodontal disease. An important gene associated with Mycobacterium Abscessus is TLR2 (Toll Like Receptor 2), and among its related pathways are Malaria and Disorders of transmembrane transporters. Affiliated tissues include lung, skin and t cells, and related mouse phenotypes are liver/biliary system and hematopoietic system.

Related Diseases for Mycobacterium Abscessus

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Diseases related to Mycobacterium Abscessus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 297)
idRelated DiseaseScoreTop Affiliating Genes
1vulvovaginitis30.4CLEC7A, NLRP3
2periodontal disease30.4CXCL8, TLR2
3melioidosis29.9TLR1, TLR2
4asthma29.5CFTR, CXCL8, NLRP3, SYK
5malaria29.4CXCL8, NLRP3, TLR1, TLR2
6immunodeficiency 28, mycobacteriosis10.5
7breast cancer10.4
8bartonellosis10.4CXCL8, TLR2
9tuberculous uveitis10.4CXCL8, TLR2
10occipital lobe neoplasm10.4CXCL8, TLR2
11auricular cancer10.3CXCL8, TLR2
12pancreatitis10.3
13neuronitis10.3
14aneurysm10.3
15aniseikonia10.3CLEC7A, TLR2
16endocarditis10.3CXCL8, SERPINA1
17alcoholic gastritis10.3CXCL8, TLR2
18colorectal cancer10.3
19prostatitis10.3
20adenocarcinoma10.3
21cerebritis10.3
22wells-jankovic syndrome10.3CXCL8, NLRP3
23astrakhan spotted fever10.3CXCL8, TLR2
24peripheral retinal degeneration10.3CXCL8, NLRP3
25lung cancer10.2
26keratitis10.2
27drug addiction10.2
28gastric cancer10.2
29hepatitis10.2
30leukemia10.2
31hypogonadism10.2
32cervicitis10.2
33macular holes10.2
34endotheliitis10.2
35bardet-biedl syndrome 810.2CXCL8, SERPINA1
36noonan-like/multiple giant cell lesion syndrome10.2CFTR, TLR2
37trachoma10.2CXCL8, TLR2
38hair defect with photosensitivity and mental retardation10.2CLEC7A, CXCL8, TLR2
39prostate cancer10.1
40obesity10.1
41allergic rhinitis10.1
42glucocorticoid resistance10.1
43bipolar disorder10.1
44pulmonary emphysema10.1
45sinusitis10.1
46intracranial aneurysm10.1
47dementia10.1
48down syndrome10.1
49lymphadenitis10.1
50astrocytoma10.1

Graphical network of the top 20 diseases related to Mycobacterium Abscessus:



Diseases related to mycobacterium abscessus

Symptoms for Mycobacterium Abscessus

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Drugs & Therapeutics for Mycobacterium Abscessus

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Drugs for Mycobacterium Abscessus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AzithromycinapprovedPhase 432283905-01-555185, 53477736, 447043
Synonyms:
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*
121470-24-4
75199_FLUKA
83905-01-5
9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A
AC-16014
AC1L9KEG
Aritromicina
Azasite
Azenil
Azifast
Azigram
Azimakrol
Azithramycine
Azithromycin
Azithromycin & Tumor Necrosis Factor
Azithromycin (AIDS Initiative)
Azithromycin (anhydrous)
Azithromycin Dihydrate
Azithromycin Monohydrate
Azithromycin Sterile
Azithromycin dihydrate
Azithromycin plus Tumor Necrosis Factor
Azithromycine
Azithromycine [French]
Azithromycinum
Azithromycinum [Latin]
Azitrocin
Azitromax
Azitromicina
Azitromicina [Spanish]
Azitromin
Azythromycin
BIDD:GT0792
BRN 5387583
BSPBio_002285
Bio-0676
C38H72N2O12
CCRIS 1961
CHEBI:2955
CHEMBL529
CID447043
CP-62993
CP62,993
CPD000471864
DCH3
DRG-0104
 
DivK1c_000233
HMS1922G12
HMS2094M11
HMS500L15
HSDB 7205
Hemomycin
IDI1_000233
KBio1_000233
KBio2_000787
KBio2_003355
KBio2_005923
KBio3_001505
KBioGR_000731
KBioSS_000787
LS-1834
MLS001055353
MLS001066331
MLS001201763
MLS001304005
MLS001332499
MLS001332500
Misultina
MolPort-002-507-426
N,N-Dimethyl-4-amino-benzaldehyde
NCGC00090753-01
NCGC00090753-02
NINDS_000233
NSC643732
SAM002589961
SMR000471864
SPBio_001544
SPECTRUM1503679
Spectrum2_001582
Spectrum3_000653
Spectrum4_000186
Spectrum5_001867
Spectrum_000307
Sumamed
Tromix
UNII-JTE4MNN1MD
XZ-450
Z-Pak
ZIT
Zentavion
Zithromac
Zithromax
Zithromax IV
Zithromycin
Zitromax
Zitromax Avium 600
Zmas
Zmax
azithromycin
2
TigecyclineapprovedPhase 253220620-09-75282044
Synonyms:
(4S,12aS)-4,7-Bis(dimethylamino)-9-{2-[(tert-butyl)amino]acetylamino}-3,10,12,12a-tetrahydroxy-1,11-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide
(4S,4AS,5ar,12as)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
(4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
121GE002
220620-09-7
9-t-Butylglycylamido minocycline
AC-1798
AC1NQZEU
C12012
CHEBI:149836
CHEMBL1212946
CHEMBL376140
CID5282044
D01079
DB00560
GAR 936
GAR-936
 
GAR-936,Tigecycline
LS-186580
LS-187002
LS-187782
N-[(5aR,6aS,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5a,6,6a,7-tetrahydro-5H-tetracen-2-yl]-2-(tert-butylamino)acetamide
S1403_Selleck
TBG-MINO
Tigeciclina
Tigecycline
Tigecycline (JAN/USAN)
Tigecycline [USAN]
Tigecyclinum
Tigilcycline
Tygacil
Tygacil (TN)
Tygacil(TM)
Tygacil, GAR-936, WAY-GAR-936, TBG-MINO, Tigecycline
UNII-70JE2N95KR
WAY-GAR-936
3Anti-Bacterial AgentsPhase 29140
4Anti-Infective AgentsPhase 217220

Interventional clinical trials:

idNameStatusNCT IDPhase
1Azithromycin in the Treatment of M. Avium Complex Lung DiseaseActive, not recruitingNCT00599079Phase 4
2Tigecycline for Treatment of Rapidly Growing MycobacteriaActive, not recruitingNCT00600600Phase 2
3Inhaled Amikacin Treatment for Nontuberculous Mycobacterial Lung DiseaseWithdrawnNCT01528930Phase 2
4The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung DiseaseRecruitingNCT02005094
5The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and BronchiolitisRecruitingNCT01354912
6PATIENCE Trial: Prospective Algorithm for Treatment of NTM in Cystic FibrosisRecruitingNCT02419989

Search NIH Clinical Center for Mycobacterium Abscessus

Genetic Tests for Mycobacterium Abscessus

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Anatomical Context for Mycobacterium Abscessus

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MalaCards organs/tissues related to Mycobacterium Abscessus:

33
Lung, Skin, T cells, Neutrophil, Heart, Liver, Breast

Animal Models for Mycobacterium Abscessus or affiliated genes

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MGI Mouse Phenotypes related to Mycobacterium Abscessus:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.4CFTR, NLRP3, SQSTM1, SYK, TLR2
2MP:00053977.0CFTR, CLEC7A, NLRP3, SQSTM1, SYK, TLR1
3MP:00053876.7CFTR, CLEC7A, NLRP3, SQSTM1, SYK, TLR1

Publications for Mycobacterium Abscessus

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Articles related to Mycobacterium Abscessus:

(show top 50)    (show all 382)
idTitleAuthorsYear
1
Early neurodevelopmental screening in tuberous sclerosis complex: a potential window of opportunity. (25160545)
2014
2
Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells. (25204797)
2014
3
Rotavirus G2P[4] and G2P[4]+[6] infections during norovirus gastroenteritis outbreak: summer season 2010, Brazil. (23740058)
2013
4
Life-threatening pharyngeal edema after sclerotherapy of oral venous malformations in a patient with blue rubber bleb nevus syndrome. (24133559)
2013
5
Gallstone ileus ten days after laparoscopic cholecystectomy. (22546112)
2012
6
EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis. (21156006)
2011
7
No association of common VCP variants with sporadic frontotemporal dementia. (17618707)
2009
8
Impact of age at first drink on vulnerability to alcohol-related problems: testing the marker hypothesis in a prospective study of young adults. (19332346)
2009
9
Crohn's disease-associated small bowel adenocarcinoma with pre-existing low-grade dysplasia: a case report. (17593171)
2007
10
Long-term anatomical and visual outcome of vitreous surgery for retinal detachment with choroidal coloboma. (17189899)
2007
11
Staged approach to the urachal cyst with infected omphalitis. (16706104)
2006
12
A giant coronary artery aneurysm in the right coronary artery. (16697928)
2006
13
Oxygen and retinopathy of prematurity. (16482198)
2006
14
Interethnic variability of warfarin maintenance requirement is explained by VKORC1 genotype in an Asian population. (16513444)
2006
15
Differential cell adhesion to vocal fold extracellular matrix constituents. (16531030)
2006
16
Receptor-antagonist interactions in the complexes of agouti and agouti-related protein with human melanocortin 1 and 4 receptors. (15736952)
2005
17
Comparison between partial agonist (ME3412) and antagonist (alosetron) of 5-hydroxytryptamine 3 receptor on gastrointestinal function. (15787949)
2005
18
Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling. (15905359)
2005
19
Images in clinical medicine. Pemphigus foliaceus. (16354895)
2005
20
Variations within OLF1/EBF-associated zinc finger protein gene confer susceptibility to lupus nephritis in Chinese population]. (16061000)
2005
21
Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist. (15608077)
2005
22
In vitro evidence for the recognition of 8-oxoGTP by Ras, a small GTP-binding protein. (15629468)
2005
23
Pendred syndrome and DFNB4-mutation screening of SLC26A4 by denaturing high-performance liquid chromatography and the identification of eleven novel mutations. (14679580)
2004
24
Circulating growth factor levels are associated with tumorigenesis in neurofibromatosis type 1. (15355893)
2004
25
An unusual combination: lipedema with myiasis. (15153906)
2004
26
Spinal cord infarction caused by malignant intramedullary glioma: the traps of epidemiology and travel history. (15176568)
2004
27
Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins. (14722252)
2004
28
The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology. (12610647)
2003
29
Cleaved beta 2-microglobulin partially attains a conformation that has amyloidogenic features. (11801591)
2002
30
Eczema herpeticum: a dermatologic emergency. (12430518)
2002
31
K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels. (11872696)
2002
32
Maternal serum hyperglycosylated human chorionic gonadotrophin (HhCG) in the first trimester of pregnancies affected by Down syndrome, using a sialic acid-specific lectin immunoassay. (12210572)
2002
33
A case of SLE presenting the features of antiphospholipid antibody syndrome during a treatment for complicated cryptococcal meningitis]. (11517489)
2001
34
Olanzapine: a review of its use in the treatment of bipolar I disorder. (11700151)
2001
35
Hypovitaminosis D myopathy without biochemical signs of osteomalacic bone involvement. (10821877)
2000
36
Soluble adhesion molecules as a marker of disease severity in human fascioliasis. (10946501)
2000
37
Transfusion to blood group A and O patients of group B RBCs that have been enzymatically converted to group O. (11099655)
2000
38
Infrequent mutation of the p16/MTS1 gene and overexpression of cyclin-dependent kinase 4 in human primary soft-tissue sarcoma. (9563903)
1998
39
Ca2+ binding to the first epidermal growth factor-like domain of factor VIIa increases amidolytic activity and tissue factor affinity. (9242658)
1997
40
Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels. (9409218)
1997
41
Brachydactyly type C gene maps to human chromsome 12q24. (8954778)
1996
42
p53 gene mutation analysis and antisense-mediated growth inhibition of human ovarian carcinoma cell lines. (8557231)
1996
43
Identification of ligand binding residues in extracellular loops of the melanocortin 1 receptor. (8605020)
1996
44
Adhalin gene mutations in patients with autosomal recessive childhood onset muscular dystrophy with adhalin deficiency. (7657792)
1995
45
Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. (7670487)
1995
46
Sequence analysis and fine specificity of two human monoclonal antibodies to histone H1. (7511211)
1994
47
Cyclic thrombocytopenia associated with IgM anti-GPIIb-IIIa autoantibodies. (7529542)
1994
48
Expression of proliferating cell nuclear antigen in superficial bladder cancer--application to paraffin-embedded tissue sections]. (8099249)
1993
49
Lidocaine inhibits stimulation-coupled responses of neutrophils and protein kinase C activity. (1966297)
1990
50
Immunological studies of dengue fever and Colorado tick fever. (20982508)
1946

Variations for Mycobacterium Abscessus

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Expression for genes affiliated with Mycobacterium Abscessus

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Search GEO for disease gene expression data for Mycobacterium Abscessus.

Pathways for genes affiliated with Mycobacterium Abscessus

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GO Terms for genes affiliated with Mycobacterium Abscessus

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Biological processes related to Mycobacterium Abscessus according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1cellular response to molecule of fungal originGO:007122610.2CLEC7A, SYK
2receptor internalizationGO:00316239.9CXCL8, SYK
3toll-like receptor 4 signaling pathwayGO:00341429.9TLR1, TLR2
4cellular response to triacyl bacterial lipopeptideGO:00717279.8TLR1, TLR2
5defense responseGO:00069529.6NLRP3, TLR1
6defense response to bacteriumGO:00427429.0SYK, TLR1
7inflammatory responseGO:00069549.0NLRP3, SYK, TLR1
8innate immune responseGO:00450878.9CLEC7A, NLRP3, SYK, TLR2
9signal transductionGO:00071658.3CXCL8, NLRP3, TLR1, TLR2

Sources for Mycobacterium Abscessus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet