MCID: MYC017
MIFTS: 40

Mycobacterium Kansasii malady

Categories: Rare diseases

Aliases & Classifications for Mycobacterium Kansasii

Aliases & Descriptions for Mycobacterium Kansasii:

Name: Mycobacterium Kansasii 50
Infection Due to Mycobacterium Kansasii 69
Mycobacterium Kansasii Infection 50
M. Kansasii 50

Classifications:



Summaries for Mycobacterium Kansasii

MalaCards based summary : Mycobacterium Kansasii, also known as infection due to mycobacterium kansasii, is related to fasciitis and tuberculosis. An important gene associated with Mycobacterium Kansasii is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and Toll-Like receptor Signaling Pathways. The drugs Estradiol and Isoniazid have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and skin, and related phenotypes are hematopoietic system and immune system

Wikipedia : 71 Mycobacterium kansasii is a bacterium in the Mycobacterium family. The genus includes species known to... more...

Related Diseases for Mycobacterium Kansasii

Diseases related to Mycobacterium Kansasii via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 99)
id Related Disease Score Top Affiliating Genes
1 fasciitis 29.5 CXCL8 TLR2
2 tuberculosis 10.5
3 arthritis 10.2
4 septic arthritis 10.2
5 tenosynovitis 10.2
6 mixed mineral dust pneumoconiosis 10.2 CD14 CXCL8
7 mycobacterium marinum 10.1
8 acquired immunodeficiency syndrome 10.1
9 osteomyelitis 10.1
10 senile reticular retinal degeneration 10.1 CXCL8 NLRP3
11 malignant histiocytosis 10.1 CXCL8 NLRP3
12 wilkes stevenson syndrome 10.1 CXCL8 NLRP3
13 skin conditions 10.1 CXCL8 NLRP3
14 baritosis 10.1 CXCL8 NLRP3
15 mycobacterium fortuitum 10.1
16 pericarditis 10.1
17 lung disease 10.1
18 thyroid hyalinizing trabecular adenoma 10.1 CXCL8 NLRP3
19 handl syndrome 10.0 CXCL8 TLR2
20 ulcerative proctitis 10.0 CXCL8 TLR2
21 stomach carcinoma in situ 10.0 CXCL8 TLR2
22 appendiceal l-cell glucagon-like peptide producing tumor 10.0 CXCL8 TLR2
23 leukemia 10.0
24 pneumonia 10.0
25 mycobacterium xenopi 10.0
26 ectothrix infectious disease 10.0 CXCL8 TLR2
27 cardioskeletal syndrome, kuwaiti type 10.0 CD14 TLR2
28 inappropriate adh syndrome 10.0 CXCL8 TLR2
29 ovarian cystic teratoma 10.0 CXCL8 TLR2
30 fibrosis of extraocular muscles, congenital, 1 10.0 CD14 TLR2
31 atrophy of prostate 10.0 CXCL8 TLR2
32 paragonimiasis 10.0 CXCL8 TLR2
33 unilateral hypoactive labyrinth 10.0 CXCL8 TLR2
34 hepatitis 9.9
35 cellulitis 9.9
36 systemic lupus erythematosus 9.9
37 lymphadenitis 9.9
38 lupus erythematosus 9.9
39 pulmonary tuberculosis 9.9
40 bursitis 9.9
41 asbestosis 9.9 CXCL8 TLR2
42 keratomalacia 9.9 CXCL8 TLR2
43 optic nerve hypoplasia 9.9 CXCL8 TLR2
44 pyoderma gangrenosum 9.9 CD14 CXCL8
45 nephropathy with pretibial epidermolysis bullosa and deafness 9.9 CXCL8 TLR2
46 pigmentation disease 9.9 CXCL8 TLR2
47 rheumatoid arthritis 9.9
48 mycobacterium chelonae 9.9
49 mycobacterium gordonae 9.9
50 myelodysplastic syndrome 9.9

Graphical network of the top 20 diseases related to Mycobacterium Kansasii:



Diseases related to Mycobacterium Kansasii

Symptoms & Phenotypes for Mycobacterium Kansasii

MGI Mouse Phenotypes related to Mycobacterium Kansasii:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.35 CD14 FN1 NLRP3 PLCG1 TLR2
2 immune system MP:0005387 9.02 FN1 NLRP3 PLCG1 TLR2 CD14

Drugs & Therapeutics for Mycobacterium Kansasii

Drugs for Mycobacterium Kansasii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757 53477783
2
Isoniazid Approved Phase 3 54-85-3 3767
3
Pyrazinamide Approved Phase 3 98-96-4 1046
4
Norgestimate Approved Phase 3 35189-28-7 6540478
5
Ofloxacin Approved Phase 3 82419-36-1 4583
6
Kanamycin Approved, Vet_approved Phase 3 8063-07-8, 59-01-8 6032
7
Moxifloxacin Approved, Investigational Phase 3 354812-41-2, 151096-09-2 152946
8
Ethambutol Approved Phase 3 74-55-5 3279 14052
9
Clofazimine Approved, Investigational Phase 3 2030-63-9 2794
10
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
11
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
12
Bedaquiline Approved Phase 3 843663-66-1
13 Estradiol valerate Phase 3 979-32-8
14
Prothionamide Phase 3 14222-60-7 666418
15 Contraceptive Agents Phase 3
16 Contraceptives, Oral Phase 3
17 Contraceptives, Oral, Combined Phase 3
18 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
19 Cytochrome P-450 Enzyme Inhibitors Phase 3
20 Norgestimate, ethinyl estradiol drug combination Phase 3
21 Topoisomerase Inhibitors Phase 3
22 Diarylquinolines Phase 3
23 Estradiol 17 beta-cypionate Phase 3
24 Estradiol 3-benzoate Phase 3
25 Anti-Bacterial Agents Phase 3
26 Hypolipidemic Agents Phase 3
27 Polyestradiol phosphate Phase 3
28 Anti-Infective Agents Phase 3
29 Fluoroquinolones Phase 3
30 Anti-Inflammatory Agents Phase 3
31 Lipid Regulating Agents Phase 3
32 Antimetabolites Phase 3
33 Renal Agents Phase 3
34 Antibiotics, Antitubercular Phase 3
35 Antitubercular Agents Phase 3

Interventional clinical trials:


id Name Status NCT ID Phase
1 The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB Recruiting NCT02409290 Phase 3
2 The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis Unknown status NCT01354912

Search NIH Clinical Center for Mycobacterium Kansasii

Genetic Tests for Mycobacterium Kansasii

Anatomical Context for Mycobacterium Kansasii

MalaCards organs/tissues related to Mycobacterium Kansasii:

39
Lung, Testes, Skin, T Cells, Lymph Node, Monocytes, Liver

Publications for Mycobacterium Kansasii

Articles related to Mycobacterium Kansasii:

(show top 50) (show all 433)
id Title Authors Year
1
Pulmonary Mycobacterium kansasii disease in immunocompetent host: Treatment outcomes with short-course chemotherapy. ( 27934834 )
2016
2
Draft Genome Sequences of Mycobacterium kansasii Strains 1010001454, 1010001458, 1010001468, 1010001493, 1010001495, and 1010001469, Isolated from Environmental Sources. ( 27257194 )
2016
3
Proposal of a new method for subtyping of Mycobacterium kansasii based upon PCR restriction enzyme analysis of the tuf gene. ( 26830053 )
2016
4
Isolated Mycobacterium kansasii wound infection and Osteomyelitis in an immunocompetent patient. ( 28031850 )
2016
5
Mycobacterium kansasii Subtype I Is Associated With Clarithromycin Resistance in China. ( 28082964 )
2016
6
Isoniazid-resistant Mycobacterium kansasii in an HIV-positive patient, and possible development of immune reconstitution inflammatory syndrome after initiation of highly active antiretroviral therapy: case report. ( 26603644 )
2016
7
Mediastinal and Disseminated Mycobacterium kansasii Disease in GATA2 Deficiency. ( 27607353 )
2016
8
Interferon-gamma release assays in patients with Mycobacterium kansasii pulmonary infection: A retrospective survey. ( 27025204 )
2016
9
Pulmonary infection caused by Mycobacterium kansasii: findings on computed tomography of the chest. ( 27777472 )
2016
10
The importance of computed tomography of the chest in cases of suspected infection with nontuberculous mycobacteria (Mycobacterium kansasii). ( 27777490 )
2016
11
Molecular characterisation of clinical and environmental isolates of Mycobacterium kansasii isolates from South African gold mines. ( 25719478 )
2015
12
Fatal aortic pseudoaneurysm from disseminated Mycobacterium kansasii infection: case report. ( 25537975 )
2015
13
Mycobacterium kansasii causing chronic monoarticular synovitis in a patient with HIV/AIDS. ( 26629306 )
2015
14
A Case of Pulmonary Mycobacterium kansasii Disease Complicated with Tension Pneumothorax. ( 26508923 )
2015
15
Rapid Drug Tolerance and Dramatic Sterilizing Effect of Moxifloxacin Monotherapy in a Novel Hollow-Fiber Model of Intracellular Mycobacterium kansasii Disease. ( 25645830 )
2015
16
Sweet's syndrome associated with Mycobacterium kansasii infection in an immunocompetent woman. ( 26086480 )
2015
17
Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. ( 26048260 )
2015
18
Cutaneous infection with Mycobacterium kansasii in a patient with myelodysplastic syndrome and Sweet syndrome. ( 26244358 )
2015
19
Clinical Significance of Mycobacterium kansasii Isolates from Respiratory Specimens. ( 26431540 )
2015
20
Immune Reconstitution Inflammatory Syndrome Secondary to Mycobacterium kansasii Infection in a Kidney Transplant Recipient. ( 26372924 )
2015
21
Insights on the Emergence of Mycobacterium tuberculosis from the Analysis of Mycobacterium kansasii. ( 25716827 )
2015
22
MKAN27435 Is Required for the Biosynthesis of Higher Subclasses of Lipooligosaccharides in Mycobacterium kansasii. ( 25893968 )
2015
23
Human-to-human transmission of Mycobacterium kansasii or victims of a shared source? ( 24969652 )
2014
24
Mycobacterium kansasii infection of the spine in a patient with sarcoidosis: a case report and literature review. ( 25153815 )
2014
25
Pulmonary Mycobacterium kansasii Infection Mimicking Malignancy on the (18)F-FDG PET Scan in a Patient Receiving Etanercept: A Case Report and Literature Review. ( 25389506 )
2014
26
Mycobacterium kansasii cutaneous infection in a patient with sarcoidosis treated with anti-TNF agents. ( 24773076 )
2014
27
Lithium inhibits growth of intracellular Mycobacterium kansasii through enhancement of macrophage apoptosis. ( 24535745 )
2014
28
Abscess resulting from Mycobacterium kansasii in the left thigh of AIDS patient. ( 24937823 )
2014
29
Comparison of the clinical courses and chemotherapy outcomes in metastatic colorectal cancer patients with and without active Mycobacterium tuberculosis or Mycobacterium kansasii infection: a retrospective study. ( 25326267 )
2014
30
Asymptomatic lung disease caused by Mycobacterium kansasii as an opportunistic infection in a patient treated with natalizumab for relapsing-remitting multiple sclerosis. ( 23959714 )
2013
31
Mastitis caused by Mycobacterium kansasii infection in a dog. ( 23808608 )
2013
32
Detection of mycobacterium kansasii using amplicons generated by the COBAS TaqMan MTB system. ( 24409683 )
2013
33
Mycobacterium kansasii-induced death of murine macrophages involves endoplasmic reticulum stress responses mediated by reactive oxygen species generation or calpain activation. ( 23264129 )
2013
34
A Case of Mycobacterium kansasii Pulmonary Disease Presenting as Endobronchial Lesions in HIV-Infected Patient. ( 24265644 )
2013
35
Mycobacterium kansasii isolation from captive South American coati (Nasua nasua). ( 23505720 )
2013
36
Tenosynovitis of the right hand. Mycobacterium kansasii. ( 24394739 )
2013
37
Mycobacterium kansasii septicemia in an AIDS patient complicated by acute respiratory distress syndrome and acute liver failure. ( 23970643 )
2013
38
Short communication: subtyping of Mycobacterium kansasii by PCR-restriction enzyme analysis of the hsp65 gene. ( 24455675 )
2013
39
A photoelectrocatalytic process that disinfects water contaminated with Mycobacterium kansasii and Mycobacterium avium. ( 24079966 )
2013
40
Uveitis with occult choroiditis due to Mycobacterium kansasii: limitations of interferon-gamma release assay (IGRA) tests (case report and mini-review on ocular non-tuberculous mycobacteria and IGRA cross-reactivity). ( 22661050 )
2012
41
hsp65 PCR-restriction analysis (PRA) with capillary electrophoresis for species identification and differentiation of Mycobacterium kansasii and Mycobacterium chelonae-Mycobacterium abscessus group. ( 22240012 )
2012
42
A case of wrist tenosynovitis caused by Mycobacterium kansasii in a renal transplant recipient. ( 22822725 )
2012
43
Mutations in the essential FAS II I^-hydroxyacyl ACP dehydratase complex confer resistance to thiacetazone in Mycobacterium tuberculosis and Mycobacterium kansasii. ( 22994892 )
2012
44
Pathological features of Mycobacterium kansasii infection in black bearded sakis (Chiropotes satanas). ( 22520255 )
2012
45
Heat-killed bacillus Calmette-GuAcrin and Mycobacterium kansasii antigen 85B combined vaccination ameliorates dermatitis in a mouse model of atopic dermatitis by inducing regulatory T cells. ( 22136598 )
2012
46
Septic subacromial bursitis caused by Mycobacterium kansasii in an immunocompromised host. ( 22645893 )
2012
47
Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection. ( 22558425 )
2012
48
Temporal interferon-gamma release response to Mycobacterium kansasii infection in an anorexia nervosa patient. ( 22859583 )
2012
49
Mycobacterium kansasii pulmonary infection: CT findings in 29 cases. ( 22396065 )
2012
50
Mycobacterium kansasii pericarditis in a kidney transplant recipient: a case report and comprehensive review of the literature. ( 22823928 )
2012

Variations for Mycobacterium Kansasii

Expression for Mycobacterium Kansasii

Search GEO for disease gene expression data for Mycobacterium Kansasii.

Pathways for Mycobacterium Kansasii

Pathways related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

(show all 27)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.61 CD14 CXCL8 FN1 NLRP3 PLCG1 TLR2
2
Show member pathways
12.63 CD14 CXCL8 NLRP3 TLR2
3
Show member pathways
12.47 CXCL8 NLRP3 TLR2
4 12.35 CXCL8 FN1 PLCG1
5
Show member pathways
12.26 CD14 FN1 PLCG1 TLR2
6 11.99 FN1 PLCG1 TLR2
7
Show member pathways
11.93 CD14 CXCL8 TLR2
8 11.62 CD14 FN1
9 11.6 CXCL8 PLCG1
10
Show member pathways
11.59 CD14 CXCL8
11 11.58 CXCL8 FN1 PLCG1
12 11.57 CXCL8 TLR2
13 11.55 CD14 CXCL8
14 11.52 CD14 CXCL8 PLCG1
15
Show member pathways
11.47 CD14 CXCL8 FN1 TLR2
16 11.43 FN1 PLCG1
17 11.43 FN1 PLCG1 TLR2
18 11.4 CXCL8 PLCG1
19 11.37 CXCL8 FN1
20 11.31 CD14 CXCL8 NLRP3
21 11.26 CXCL8 TLR2
22 11.2 CXCL8 FN1
23 11.07 CXCL8 FN1
24 11.07 CD14 CXCL8 TLR2
25 10.92 NLRP3 TLR2
26 10.91 CD14 CXCL8 FN1 TLR2
27 10.74 CXCL8 FN1

GO Terms for Mycobacterium Kansasii

Cellular components related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 secretory granule membrane GO:0030667 8.62 CD14 TLR2

Biological processes related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.72 CD14 NLRP3 TLR2
2 immune system process GO:0002376 9.71 CD14 NLRP3 TLR2
3 inflammatory response GO:0006954 9.67 CD14 CXCL8 NLRP3 TLR2
4 cellular response to lipopolysaccharide GO:0071222 9.61 CD14 CXCL8 NLRP3
5 calcium-mediated signaling GO:0019722 9.52 CXCL8 PLCG1
6 positive regulation of tumor necrosis factor production GO:0032760 9.51 CD14 TLR2
7 toll-like receptor signaling pathway GO:0002224 9.49 CD14 TLR2
8 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.48 CD14 TLR2
9 lipopolysaccharide-mediated signaling pathway GO:0031663 9.46 CD14 TLR2
10 cellular response to lipoteichoic acid GO:0071223 9.4 CD14 TLR2
11 cellular response to diacyl bacterial lipopeptide GO:0071726 9.32 CD14 TLR2
12 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.26 CD14 TLR2
13 cellular response to triacyl bacterial lipopeptide GO:0071727 9.16 CD14 TLR2
14 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 8.96 CD14 TLR2
15 response to molecule of bacterial origin GO:0002237 8.8 CD14 CXCL8 TLR2

Molecular functions related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 lipopolysaccharide binding GO:0001530 9.16 CD14 TLR2
2 peptidoglycan binding GO:0042834 8.96 NLRP3 TLR2
3 lipopeptide binding GO:0071723 8.62 CD14 TLR2

Sources for Mycobacterium Kansasii

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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