MCID: MYC017
MIFTS: 42

Mycobacterium Kansasii

Categories: Rare diseases

Aliases & Classifications for Mycobacterium Kansasii

MalaCards integrated aliases for Mycobacterium Kansasii:

Name: Mycobacterium Kansasii 49
Infection Due to Mycobacterium Kansasii 69
Mycobacterium Kansasii Infection 49
M. Kansasii 49

Classifications:



External Ids:

UMLS 69 C0275706

Summaries for Mycobacterium Kansasii

MalaCards based summary : Mycobacterium Kansasii, also known as infection due to mycobacterium kansasii, is related to septic arthritis and silicosis. An important gene associated with Mycobacterium Kansasii is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and Toll-Like receptor Signaling Pathways. The drugs Estradiol and Isoniazid have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and testes.

Wikipedia : 72 Mycobacterium kansasii is a bacterium in the Mycobacterium family. The genus includes species known to... more...

Related Diseases for Mycobacterium Kansasii

Diseases related to Mycobacterium Kansasii via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 septic arthritis 30.3 CXCL8 TLR2
2 silicosis 29.8 CXCL8 NLRP3
3 bone inflammation disease 29.7 CXCL8 NLRP3
4 mastitis 29.6 CXCL8 TLR2
5 peritonitis 29.4 CXCL8 TLR2
6 mycobacterium chelonae 29.4 CD14 CXCL8 TLR2
7 mycobacterium abscessus 29.2 CXCL8 NLRP3 TLR2
8 mycobacterium tuberculosis 1 10.6
9 arthritis 10.3
10 osteomyelitis 10.3
11 tenosynovitis 10.3
12 acquired immunodeficiency syndrome 10.2
13 mycobacterium marinum 10.2
14 viral meningitis 10.2 CD14 CXCL8
15 leukemia 10.1
16 mycobacterium fortuitum 10.1
17 pneumonia 10.1
18 pericarditis 10.1
19 lung disease 10.1
20 aseptic meningitis 10.1 CXCL8 NLRP3
21 lymphadenitis 10.1
22 mycobacterium xenopi 10.1
23 pyoderma gangrenosum 10.1 CXCL8 NLRP3
24 wells syndrome 10.1 CXCL8 NLRP3
25 paroxysmal nocturnal hemoglobinuria 10.1 CD14 PLCG1
26 conjunctivitis 10.0 CXCL8 NLRP3
27 cellulitis 10.0
28 mononeuropathy of the median nerve, mild 10.0
29 mediastinitis 10.0
30 carpal tunnel syndrome 10.0
31 lupus erythematosus 10.0
32 systemic lupus erythematosus 10.0
33 pulmonary tuberculosis 10.0
34 bursitis 10.0
35 hepatitis 10.0
36 pneumoconiosis 10.0 CXCL8 NLRP3
37 monocytic leukemia 10.0 CD14 CXCL8
38 haemophilus influenzae 10.0 CXCL8 TLR2
39 sebaceous gland disease 10.0 CXCL8 TLR2
40 tuberculous meningitis 10.0 CXCL8 TLR2
41 mycobacterium gordonae 10.0
42 myelodysplastic syndrome 10.0
43 hairy cell leukemia 10.0
44 rheumatoid arthritis 10.0
45 olecranon bursitis 10.0
46 middle ear disease 9.9 CXCL8 TLR2
47 invasive aspergillosis 9.9 CXCL8 TLR2
48 bacterial vaginosis 9.9 CXCL8 TLR2
49 myd88 deficiency 9.9 CD14 TLR2
50 leptospirosis 9.9 CXCL8 TLR2

Graphical network of the top 20 diseases related to Mycobacterium Kansasii:



Diseases related to Mycobacterium Kansasii

Symptoms & Phenotypes for Mycobacterium Kansasii

Drugs & Therapeutics for Mycobacterium Kansasii

Drugs for Mycobacterium Kansasii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
2
Isoniazid Approved, Investigational Phase 3 54-85-3 3767
3
Pyrazinamide Approved, Investigational Phase 3 98-96-4 1046
4
Norgestimate Approved, Investigational Phase 3 35189-28-7 6540478
5
Ofloxacin Approved Phase 3 82419-36-1 4583
6
Kanamycin Approved, Investigational, Vet_approved Phase 3 59-01-8, 8063-07-8 6032
7
Moxifloxacin Approved, Investigational Phase 3 151096-09-2, 354812-41-2 152946
8
Ethambutol Approved Phase 3 74-55-5 14052 3279
9
Clofazimine Approved, Investigational Phase 3 2030-63-9 2794
10
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
11
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
12
Bedaquiline Approved Phase 3 843663-66-1
13
Prothionamide Approved, Investigational Phase 3 14222-60-7 666418
14 Estradiol valerate Phase 3 979-32-8
15 Renal Agents Phase 3
16 Fluoroquinolones Phase 3
17 Topoisomerase Inhibitors Phase 3
18 Contraceptive Agents Phase 3
19 Contraceptives, Oral Phase 3
20 Contraceptives, Oral, Combined Phase 3
21 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
22 Cytochrome P-450 Enzyme Inhibitors Phase 3
23 Norgestimate, ethinyl estradiol drug combination Phase 3
24 Diarylquinolines Phase 3
25 Anti-Bacterial Agents Phase 3
26 Estradiol 17 beta-cypionate Phase 3
27 Estradiol 3-benzoate Phase 3
28 Hypolipidemic Agents Phase 3
29 Anti-Infective Agents Phase 3
30 Polyestradiol phosphate Phase 3
31 Antimetabolites Phase 3
32 Anti-Inflammatory Agents Phase 3
33 Lipid Regulating Agents Phase 3
34 Antibiotics, Antitubercular Phase 3
35 Antitubercular Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB Recruiting NCT02409290 Phase 3 Regimen A locally-used WHO-approved MDR-TB regimen;Moxifloxacin;Clofazimine;Ethambutol;Pyrazinamide;Isoniazid;Prothionamide;Kanamycin;Levofloxacin;Bedaquiline
2 The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis Unknown status NCT01354912

Search NIH Clinical Center for Mycobacterium Kansasii

Genetic Tests for Mycobacterium Kansasii

Anatomical Context for Mycobacterium Kansasii

MalaCards organs/tissues related to Mycobacterium Kansasii:

38
Lung, Skin, Testes, T Cells, Lymph Node, Monocytes, Liver

Publications for Mycobacterium Kansasii

Articles related to Mycobacterium Kansasii:

(show top 50) (show all 449)
# Title Authors Year
1
Drug susceptibility profiling and genetic determinants of drug resistance in<i>Mycobacterium kansasii</i>. ( 29437627 )
2018
2
Mycobacterium persicum sp. nov., a novel species closely related to Mycobacterium kansasii and Mycobacterium gastri. ( 28629501 )
2017
3
Mycobacterium kansasii. ( 28185617 )
2017
4
Mycobacterium kansasii Pneumonia with Mediastinal Lymphadenitis in a Patient with Acute Myeloid Leukemia: Successful Treatment to Stem Cell Transplantation. ( 28271647 )
2017
5
Mycobacterium kansasii Isolated from Tuberculinpositive Rhesus Macaques (Macaca mulatta) in the Absence of Disease. ( 28830585 )
2017
6
Osteomyelitis due to Mycobacterium kansasii in a patient with sarcoidosis. ( 28529884 )
2017
7
Disseminated Mycobacterium kansasii infection with cutaneous lesions in an immunocompetent patient. ( 28712930 )
2017
8
Complete Genome Sequences of Mycobacterium kansasii Strains Isolated from Rhesus Macaques. ( 28428296 )
2017
9
Disseminated cutaneous Mycobacterium kansasii infection presenting with Rosai-Dorfman disease-like histological features in a patient carrying anti-interferon-I^ autoantibodies. ( 28836691 )
2017
10
Draft Genome Sequences of Mycobacterium kansasii Clinical Strains. ( 28572311 )
2017
11
Mycobacterium kansasii Infection in a Patient Receiving Biologic Therapy-Not All Reactive Interferon Gamma Release Assays Are Tuberculosis. ( 28317629 )
2017
12
Mycotic aortic pseudoaneurysms in a patient with active Mycobacterium kansasii infection. ( 28342513 )
2017
13
A Patient-Based Analysis of the Geographic Distribution of Mycobacterium avium complex, Mycobacterium abscessus, and Mycobacterium kansasii Infections in the United States. ( 28390637 )
2017
14
Systemic Mycobacterium kansasii Infection in a Domestic Shorthair Cat. ( 28942306 )
2017
15
Mycobacterium kansasii: A Rare Cause of Brain Abscess. ( 28104110 )
2017
16
Mycobacterium Kansasii ( 28613656 )
2017
17
Isoniazid-resistant Mycobacterium kansasii in an HIV-positive patient, and possible development of immune reconstitution inflammatory syndrome after initiation of highly active antiretroviral therapy: case report. ( 26603644 )
2016
18
Mediastinal and Disseminated Mycobacterium kansasii Disease in GATA2 Deficiency. ( 27607353 )
2016
19
Draft Genome Sequences of Mycobacterium kansasii Strains 1010001454, 1010001458, 1010001468, 1010001493, 1010001495, and 1010001469, Isolated from Environmental Sources. ( 27257194 )
2016
20
Pulmonary Mycobacterium kansasii disease in immunocompetent host: Treatment outcomes with short-course chemotherapy. ( 27934834 )
2016
21
Interferon-gamma release assays in patients with Mycobacterium kansasii pulmonary infection: A retrospective survey. ( 27025204 )
2016
22
Proposal of a new method for subtyping of Mycobacterium kansasii based upon PCR restriction enzyme analysis of the tuf gene. ( 26830053 )
2016
23
Pulmonary infection caused by Mycobacterium kansasii: findings on computed tomography of the chest. ( 27777472 )
2016
24
The importance of computed tomography of the chest in cases of suspected infection with nontuberculous mycobacteria (Mycobacterium kansasii). ( 27777490 )
2016
25
Mycobacterium kansasii Subtype I Is Associated With Clarithromycin Resistance in China. ( 28082964 )
2016
26
Isolated Mycobacterium kansasii wound infection and Osteomyelitis in an immunocompetent patient. ( 28031850 )
2016
27
MKAN27435 Is Required for the Biosynthesis of Higher Subclasses of Lipooligosaccharides in Mycobacterium kansasii. ( 25893968 )
2015
28
Clinical Significance of Mycobacterium kansasii Isolates from Respiratory Specimens. ( 26431540 )
2015
29
Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. ( 26048260 )
2015
30
Fatal aortic pseudoaneurysm from disseminated Mycobacterium kansasii infection: case report. ( 25537975 )
2015
31
Rapid Drug Tolerance and Dramatic Sterilizing Effect of Moxifloxacin Monotherapy in a Novel Hollow-Fiber Model of Intracellular Mycobacterium kansasii Disease. ( 25645830 )
2015
32
Mycobacterium kansasii causing chronic monoarticular synovitis in a patient with HIV/AIDS. ( 26629306 )
2015
33
Insights on the Emergence of Mycobacterium tuberculosis from the Analysis of Mycobacterium kansasii. ( 25716827 )
2015
34
A Case of Pulmonary Mycobacterium kansasii Disease Complicated with Tension Pneumothorax. ( 26508923 )
2015
35
Sweet's syndrome associated with Mycobacterium kansasii infection in an immunocompetent woman. ( 26086480 )
2015
36
Immune Reconstitution Inflammatory Syndrome Secondary to Mycobacterium kansasii Infection in a Kidney Transplant Recipient. ( 26372924 )
2015
37
Molecular characterisation of clinical and environmental isolates of Mycobacterium kansasii isolates from South African gold mines. ( 25719478 )
2015
38
Cutaneous infection with Mycobacterium kansasii in a patient with myelodysplastic syndrome and Sweet syndrome. ( 26244358 )
2015
39
Pulmonary Mycobacterium kansasii Infection Mimicking Malignancy on the (18)F-FDG PET Scan in a Patient Receiving Etanercept: A Case Report and Literature Review. ( 25389506 )
2014
40
Mycobacterium kansasii infection of the spine in a patient with sarcoidosis: a case report and literature review. ( 25153815 )
2014
41
Abscess resulting from Mycobacterium kansasii in the left thigh of AIDS patient. ( 24937823 )
2014
42
Human-to-human transmission of Mycobacterium kansasii or victims of a shared source? ( 24969652 )
2014
43
Comparison of the clinical courses and chemotherapy outcomes in metastatic colorectal cancer patients with and without active Mycobacterium tuberculosis or Mycobacterium kansasii infection: a retrospective study. ( 25326267 )
2014
44
Lithium inhibits growth of intracellular Mycobacterium kansasii through enhancement of macrophage apoptosis. ( 24535745 )
2014
45
Mycobacterium kansasii cutaneous infection in a patient with sarcoidosis treated with anti-TNF agents. ( 24773076 )
2014
46
Mycobacterium kansasii septicemia in an AIDS patient complicated by acute respiratory distress syndrome and acute liver failure. ( 23970643 )
2013
47
Mastitis caused by Mycobacterium kansasii infection in a dog. ( 23808608 )
2013
48
Mycobacterium kansasii-induced death of murine macrophages involves endoplasmic reticulum stress responses mediated by reactive oxygen species generation or calpain activation. ( 23264129 )
2013
49
Asymptomatic lung disease caused by Mycobacterium kansasii as an opportunistic infection in a patient treated with natalizumab for relapsing-remitting multiple sclerosis. ( 23959714 )
2013
50
A photoelectrocatalytic process that disinfects water contaminated with Mycobacterium kansasii and Mycobacterium avium. ( 24079966 )
2013

Variations for Mycobacterium Kansasii

Expression for Mycobacterium Kansasii

Search GEO for disease gene expression data for Mycobacterium Kansasii.

Pathways for Mycobacterium Kansasii

Pathways related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.61 CD14 CXCL8 FN1 NLRP3 PLCG1 TLR2
2
Show member pathways
12.58 CD14 CXCL8 NLRP3 TLR2
3 12.53 CXCL8 FN1 PLCG1
4
Show member pathways
12.49 CXCL8 NLRP3 TLR2
5
Show member pathways
12.27 CXCL8 PLCG1 TLR2
6
Show member pathways
12.26 CD14 FN1 PLCG1 TLR2
7
Show member pathways
12.22 CD14 CXCL8 TLR2
8 11.99 FN1 PLCG1 TLR2
9
Show member pathways
11.95 CD14 CXCL8 TLR2
10
Show member pathways
11.89 CXCL8 FN1 PLCG1
11 11.63 CD14 FN1
12 11.61 CXCL8 PLCG1
13
Show member pathways
11.61 CD14 CXCL8
14 11.59 CXCL8 TLR2
15 11.58 CXCL8 FN1 PLCG1
16 11.56 CD14 CXCL8
17 11.52 CD14 CXCL8 PLCG1
18
Show member pathways
11.47 CD14 CXCL8 FN1 TLR2
19 11.44 FN1 PLCG1
20 11.43 FN1 PLCG1 TLR2
21 11.41 CXCL8 PLCG1
22 11.38 CXCL8 FN1
23 11.31 CD14 CXCL8 NLRP3
24 11.27 CXCL8 TLR2
25 11.21 CXCL8 FN1
26 11.07 CXCL8 FN1
27 11.07 CD14 CXCL8 TLR2
28 10.92 NLRP3 TLR2
29 10.91 CD14 CXCL8 FN1 TLR2
30 10.76 CXCL8 FN1

GO Terms for Mycobacterium Kansasii

Biological processes related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.74 CD14 NLRP3 TLR2
2 immune system process GO:0002376 9.73 CD14 NLRP3 TLR2
3 inflammatory response GO:0006954 9.71 CD14 CXCL8 NLRP3 TLR2
4 cellular response to lipopolysaccharide GO:0071222 9.61 CD14 CXCL8 NLRP3
5 defense response to Gram-positive bacterium GO:0050830 9.58 NLRP3 TLR2
6 calcium-mediated signaling GO:0019722 9.55 CXCL8 PLCG1
7 positive regulation of tumor necrosis factor production GO:0032760 9.54 CD14 TLR2
8 toll-like receptor signaling pathway GO:0002224 9.52 CD14 TLR2
9 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.51 CD14 TLR2
10 lipopolysaccharide-mediated signaling pathway GO:0031663 9.49 CD14 TLR2
11 positive regulation of interleukin-8 secretion GO:2000484 9.48 CD14 TLR2
12 cellular response to lipoteichoic acid GO:0071223 9.46 CD14 TLR2
13 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.37 CD14 TLR2
14 cellular response to diacyl bacterial lipopeptide GO:0071726 9.32 CD14 TLR2
15 cytokine secretion involved in immune response GO:0002374 9.26 NLRP3 TLR2
16 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 9.16 CD14 TLR2
17 cellular response to triacyl bacterial lipopeptide GO:0071727 8.96 CD14 TLR2
18 response to molecule of bacterial origin GO:0002237 8.8 CD14 CXCL8 TLR2

Molecular functions related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopolysaccharide binding GO:0001530 9.16 CD14 TLR2
2 peptidoglycan binding GO:0042834 8.96 NLRP3 TLR2
3 lipopeptide binding GO:0071723 8.62 CD14 TLR2

Sources for Mycobacterium Kansasii

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....