MCID: MYC017
MIFTS: 38

Mycobacterium Kansasii

Categories: Rare diseases

Aliases & Classifications for Mycobacterium Kansasii

MalaCards integrated aliases for Mycobacterium Kansasii:

Name: Mycobacterium Kansasii 50
Infection Due to Mycobacterium Kansasii 69
Mycobacterium Kansasii Infection 50
M. Kansasii 50

Classifications:



Summaries for Mycobacterium Kansasii

MalaCards based summary : Mycobacterium Kansasii, also known as infection due to mycobacterium kansasii, is related to sinusitis and mycobacterium xenopi. An important gene associated with Mycobacterium Kansasii is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and Toll-Like receptor Signaling Pathways. The drugs Bedaquiline and Clofazimine have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and testes.

Wikipedia : 72 Mycobacterium kansasii is a bacterium in the Mycobacterium family. The genus includes species known to... more...

Related Diseases for Mycobacterium Kansasii

Diseases related to Mycobacterium Kansasii via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 105)
id Related Disease Score Top Affiliating Genes
1 sinusitis 29.8 CXCL8 NLRP3
2 mycobacterium xenopi 26.9 CD14 CXCL8 FN1 NLRP3 PLCG1 TLR2
3 tuberculosis 10.5
4 pneumoconiosis 10.4 CD14 CXCL8
5 arthritis 10.2
6 senile reticular retinal degeneration 10.2 CXCL8 NLRP3
7 lip cancer 10.2 CXCL8 NLRP3
8 whistling face syndrome, recessive form 10.2 CXCL8 NLRP3
9 pemphigus vulgaris 10.2 CD14 PLCG1
10 osteomyelitis 10.2
11 septic arthritis 10.2
12 tenosynovitis 10.2
13 corneal intraepithelial neoplasm 10.1 CXCL8 NLRP3
14 asbestosis 10.1 CXCL8 NLRP3
15 acquired immunodeficiency syndrome 10.1
16 mycobacterium marinum 10.1
17 reticulosarcoma 10.1 CD14 CXCL8
18 leukemia 10.1
19 pericarditis 10.1
20 pneumonia 10.1
21 lung disease 10.1
22 mycobacterium fortuitum 10.1
23 halal setton wang syndrome 10.0 CXCL8 TLR2
24 granuloma inguinale 10.0 CXCL8 TLR2
25 tumefactive multiple sclerosis 10.0 CXCL8 TLR2
26 thymus clear cell carcinoma 10.0 CXCL8 TLR2
27 lymphadenitis 10.0
28 testicular infarct 10.0 CXCL8 TLR2
29 tinea barbae 10.0 CXCL8 TLR2
30 palmoplantar keratosis 10.0 CXCL8 TLR2
31 anal atresia, hypospadias, and penoscrotal inversion 10.0 CD14 TLR2
32 atrophy of prostate 10.0 CXCL8 TLR2
33 invasive pneumococcal disease, recurrent isolated, 1 9.9 CD14 TLR2
34 chronic endophthalmitis 9.9 CXCL8 TLR2
35 systemic lupus erythematosus 9.9
36 hepatitis 9.9
37 pulmonary tuberculosis 9.9
38 bursitis 9.9
39 cellulitis 9.9
40 mediastinitis 9.9
41 lupus erythematosus 9.9
42 sheehan syndrome 9.9 CXCL8 TLR2
43 mixed mineral dust pneumoconiosis 9.9 CXCL8 TLR2
44 mucocutaneous leishmaniasis 9.9 CXCL8 TLR2
45 keratomalacia 9.9 CXCL8 TLR2
46 rheumatoid arthritis 9.9
47 myelodysplastic syndrome 9.9
48 olecranon bursitis 9.9
49 hairy cell leukemia 9.9
50 mycobacterium abscessus 9.9

Graphical network of the top 20 diseases related to Mycobacterium Kansasii:



Diseases related to Mycobacterium Kansasii

Symptoms & Phenotypes for Mycobacterium Kansasii

Drugs & Therapeutics for Mycobacterium Kansasii

Drugs for Mycobacterium Kansasii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bedaquiline Approved Phase 3 843663-66-1
2
Clofazimine Approved, Investigational Phase 3 2030-63-9 2794
3
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
4
Ethambutol Approved Phase 3 74-55-5 3279 14052
5
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
6
Isoniazid Approved Phase 3 54-85-3 3767
7
Kanamycin Approved, Vet_approved Phase 3 8063-07-8, 59-01-8 6032
8
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
9
Moxifloxacin Approved, Investigational Phase 3 354812-41-2, 151096-09-2 152946
10
Norgestimate Approved Phase 3 35189-28-7 6540478
11
Ofloxacin Approved Phase 3 82419-36-1 4583
12
Pyrazinamide Approved Phase 3 98-96-4 1046
13
Prothionamide Investigational Phase 3 14222-60-7 666418
14 Anti-Bacterial Agents Phase 3
15 Antibiotics, Antitubercular Phase 3
16 Anti-Infective Agents Phase 3
17 Anti-Inflammatory Agents Phase 3
18 Antimetabolites Phase 3
19 Antitubercular Agents Phase 3
20 Contraceptive Agents Phase 3
21 Contraceptives, Oral Phase 3
22 Contraceptives, Oral, Combined Phase 3
23 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
24 Cytochrome P-450 Enzyme Inhibitors Phase 3
25 Diarylquinolines Phase 3
26 Estradiol 17 beta-cypionate Phase 3
27 Estradiol 3-benzoate Phase 3
28 Estradiol valerate Phase 3 979-32-8
29 Fluoroquinolones Phase 3
30 Hypolipidemic Agents Phase 3
31 Lipid Regulating Agents Phase 3
32 Norgestimate, ethinyl estradiol drug combination Phase 3
33 Polyestradiol phosphate Phase 3
34 Renal Agents Phase 3
35 Topoisomerase Inhibitors Phase 3

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB Recruiting NCT02409290 Phase 3 Regimen A locally-used WHO-approved MDR-TB regimen;Moxifloxacin;Clofazimine;Ethambutol;Pyrazinamide;Isoniazid;Prothionamide;Kanamycin;Levofloxacin;Bedaquiline
2 The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis Unknown status NCT01354912

Search NIH Clinical Center for Mycobacterium Kansasii

Genetic Tests for Mycobacterium Kansasii

Anatomical Context for Mycobacterium Kansasii

MalaCards organs/tissues related to Mycobacterium Kansasii:

39
Lung, Skin, Testes, T Cells, Lymph Node, Monocytes, Liver

Publications for Mycobacterium Kansasii

Articles related to Mycobacterium Kansasii:

(show top 50) (show all 448)
id Title Authors Year
1
Draft Genome Sequences of Mycobacterium kansasii Clinical Strains. ( 28572311 )
2017
2
Osteomyelitis due to Mycobacterium kansasii in a patient with sarcoidosis. ( 28529884 )
2017
3
Mycobacterium persicum sp. nov., a novel species closely related to Mycobacterium kansasii and Mycobacterium gastri. ( 28629501 )
2017
4
Mycobacterium kansasii Pneumonia with Mediastinal Lymphadenitis in a Patient with Acute Myeloid Leukemia: Successful Treatment to Stem Cell Transplantation. ( 28271647 )
2017
5
Mycobacterium kansasii Isolated from Tuberculinpositive Rhesus Macaques (Macaca mulatta) in the Absence of Disease. ( 28830585 )
2017
6
Mycobacterium kansasii Infection in a Patient Receiving Biologic Therapy-Not All Reactive Interferon Gamma Release Assays Are Tuberculosis. ( 28317629 )
2017
7
Mycobacterium kansasii. ( 28185617 )
2017
8
Mycobacterium kansasii: A Rare Cause of Brain Abscess. ( 28104110 )
2017
9
Complete Genome Sequences of Mycobacterium kansasii Strains Isolated from Rhesus Macaques. ( 28428296 )
2017
10
Mycotic aortic pseudoaneurysms in a patient with active Mycobacterium kansasii infection. ( 28342513 )
2017
11
Systemic Mycobacterium kansasii Infection in a Domestic Shorthair Cat. ( 28942306 )
2017
12
Mycobacterium Kansasii ( 28613656 )
2017
13
Disseminated Mycobacterium kansasii infection with cutaneous lesions in an immunocompetent patient. ( 28712930 )
2017
14
A Patient-Based Analysis of the Geographic Distribution of Mycobacterium avium complex, Mycobacterium abscessus, and Mycobacterium kansasii Infections in the United States. ( 28390637 )
2017
15
Disseminated cutaneous Mycobacterium kansasii infection presenting with Rosai-Dorfman disease-like histological features in a patient carrying anti-interferon-I^ autoantibodies. ( 28836691 )
2017
16
Mycobacterium kansasii Subtype I Is Associated With Clarithromycin Resistance in China. ( 28082964 )
2016
17
Mediastinal and Disseminated Mycobacterium kansasii Disease in GATA2 Deficiency. ( 27607353 )
2016
18
The importance of computed tomography of the chest in cases of suspected infection with nontuberculous mycobacteria (Mycobacterium kansasii). ( 27777490 )
2016
19
Proposal of a new method for subtyping of Mycobacterium kansasii based upon PCR restriction enzyme analysis of the tuf gene. ( 26830053 )
2016
20
Isolated Mycobacterium kansasii wound infection and Osteomyelitis in an immunocompetent patient. ( 28031850 )
2016
21
Pulmonary Mycobacterium kansasii disease in immunocompetent host: Treatment outcomes with short-course chemotherapy. ( 27934834 )
2016
22
Interferon-gamma release assays in patients with Mycobacterium kansasii pulmonary infection: A retrospective survey. ( 27025204 )
2016
23
Pulmonary infection caused by Mycobacterium kansasii: findings on computed tomography of the chest. ( 27777472 )
2016
24
Isoniazid-resistant Mycobacterium kansasii in an HIV-positive patient, and possible development of immune reconstitution inflammatory syndrome after initiation of highly active antiretroviral therapy: case report. ( 26603644 )
2016
25
Draft Genome Sequences of Mycobacterium kansasii Strains 1010001454, 1010001458, 1010001468, 1010001493, 1010001495, and 1010001469, Isolated from Environmental Sources. ( 27257194 )
2016
26
MKAN27435 Is Required for the Biosynthesis of Higher Subclasses of Lipooligosaccharides in Mycobacterium kansasii. ( 25893968 )
2015
27
Insights on the Emergence of Mycobacterium tuberculosis from the Analysis of Mycobacterium kansasii. ( 25716827 )
2015
28
Mycobacterium kansasii causing chronic monoarticular synovitis in a patient with HIV/AIDS. ( 26629306 )
2015
29
Clinical Significance of Mycobacterium kansasii Isolates from Respiratory Specimens. ( 26431540 )
2015
30
Molecular characterisation of clinical and environmental isolates of Mycobacterium kansasii isolates from South African gold mines. ( 25719478 )
2015
31
Fatal aortic pseudoaneurysm from disseminated Mycobacterium kansasii infection: case report. ( 25537975 )
2015
32
Rapid Drug Tolerance and Dramatic Sterilizing Effect of Moxifloxacin Monotherapy in a Novel Hollow-Fiber Model of Intracellular Mycobacterium kansasii Disease. ( 25645830 )
2015
33
Immune Reconstitution Inflammatory Syndrome Secondary to Mycobacterium kansasii Infection in a Kidney Transplant Recipient. ( 26372924 )
2015
34
Sweet's syndrome associated with Mycobacterium kansasii infection in an immunocompetent woman. ( 26086480 )
2015
35
A Case of Pulmonary Mycobacterium kansasii Disease Complicated with Tension Pneumothorax. ( 26508923 )
2015
36
Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. ( 26048260 )
2015
37
Cutaneous infection with Mycobacterium kansasii in a patient with myelodysplastic syndrome and Sweet syndrome. ( 26244358 )
2015
38
Human-to-human transmission of Mycobacterium kansasii or victims of a shared source? ( 24969652 )
2014
39
Comparison of the clinical courses and chemotherapy outcomes in metastatic colorectal cancer patients with and without active Mycobacterium tuberculosis or Mycobacterium kansasii infection: a retrospective study. ( 25326267 )
2014
40
Mycobacterium kansasii infection of the spine in a patient with sarcoidosis: a case report and literature review. ( 25153815 )
2014
41
Mycobacterium kansasii cutaneous infection in a patient with sarcoidosis treated with anti-TNF agents. ( 24773076 )
2014
42
Abscess resulting from Mycobacterium kansasii in the left thigh of AIDS patient. ( 24937823 )
2014
43
Pulmonary Mycobacterium kansasii Infection Mimicking Malignancy on the (18)F-FDG PET Scan in a Patient Receiving Etanercept: A Case Report and Literature Review. ( 25389506 )
2014
44
Lithium inhibits growth of intracellular Mycobacterium kansasii through enhancement of macrophage apoptosis. ( 24535745 )
2014
45
Mycobacterium kansasii septicemia in an AIDS patient complicated by acute respiratory distress syndrome and acute liver failure. ( 23970643 )
2013
46
Short communication: subtyping of Mycobacterium kansasii by PCR-restriction enzyme analysis of the hsp65 gene. ( 24455675 )
2013
47
Mycobacterium kansasii isolation from captive South American coati (Nasua nasua). ( 23505720 )
2013
48
A photoelectrocatalytic process that disinfects water contaminated with Mycobacterium kansasii and Mycobacterium avium. ( 24079966 )
2013
49
Detection of mycobacterium kansasii using amplicons generated by the COBAS TaqMan MTB system. ( 24409683 )
2013
50
Mycobacterium kansasii-induced death of murine macrophages involves endoplasmic reticulum stress responses mediated by reactive oxygen species generation or calpain activation. ( 23264129 )
2013

Variations for Mycobacterium Kansasii

Expression for Mycobacterium Kansasii

Search GEO for disease gene expression data for Mycobacterium Kansasii.

Pathways for Mycobacterium Kansasii

Pathways related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

(show all 27)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.6 CD14 CXCL8 FN1 NLRP3 PLCG1 TLR2
2
Show member pathways
12.59 CD14 CXCL8 NLRP3 TLR2
3
Show member pathways
12.55 CD14 CXCL8 TLR2
4
Show member pathways
12.47 CXCL8 NLRP3 TLR2
5 12.34 CXCL8 FN1 PLCG1
6
Show member pathways
12.26 CD14 FN1 PLCG1 TLR2
7 11.98 FN1 PLCG1 TLR2
8 11.62 CD14 FN1
9 11.6 CXCL8 PLCG1
10
Show member pathways
11.59 CD14 CXCL8
11 11.58 CXCL8 FN1 PLCG1
12 11.57 CXCL8 TLR2
13 11.55 CD14 CXCL8
14 11.52 CD14 CXCL8 PLCG1
15
Show member pathways
11.47 CD14 CXCL8 FN1 TLR2
16 11.43 FN1 PLCG1 TLR2
17 11.42 FN1 PLCG1
18 11.4 CXCL8 PLCG1
19 11.36 CXCL8 FN1
20 11.31 CD14 CXCL8 NLRP3
21 11.25 CXCL8 TLR2
22 11.19 CXCL8 FN1
23 11.07 CD14 CXCL8 TLR2
24 11.05 CXCL8 FN1
25 10.91 NLRP3 TLR2
26 10.91 CD14 CXCL8 FN1 TLR2
27 10.76 CXCL8 FN1

GO Terms for Mycobacterium Kansasii

Biological processes related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

(show all 16)
id Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.73 CD14 NLRP3 TLR2
2 immune system process GO:0002376 9.72 CD14 NLRP3 TLR2
3 inflammatory response GO:0006954 9.67 CD14 CXCL8 NLRP3 TLR2
4 cellular response to lipopolysaccharide GO:0071222 9.61 CD14 CXCL8 NLRP3
5 calcium-mediated signaling GO:0019722 9.54 CXCL8 PLCG1
6 positive regulation of tumor necrosis factor production GO:0032760 9.52 CD14 TLR2
7 toll-like receptor signaling pathway GO:0002224 9.51 CD14 TLR2
8 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.49 CD14 TLR2
9 lipopolysaccharide-mediated signaling pathway GO:0031663 9.48 CD14 TLR2
10 cellular response to lipoteichoic acid GO:0071223 9.4 CD14 TLR2
11 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.32 CD14 TLR2
12 cellular response to diacyl bacterial lipopeptide GO:0071726 9.26 CD14 TLR2
13 positive regulation of interleukin-8 secretion GO:2000484 9.16 CD14
14 cellular response to triacyl bacterial lipopeptide GO:0071727 9.16 CD14 TLR2
15 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 8.96 CD14 TLR2
16 response to molecule of bacterial origin GO:0002237 8.8 CD14 CXCL8 TLR2

Molecular functions related to Mycobacterium Kansasii according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 lipopolysaccharide binding GO:0001530 9.16 CD14 TLR2
2 peptidoglycan binding GO:0042834 8.96 NLRP3 TLR2
3 lipopeptide binding GO:0071723 8.62 CD14 TLR2

Sources for Mycobacterium Kansasii

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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