MCID: MYC019
MIFTS: 43

Mycobacterium Marinum malady

Rare diseases category
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Summaries for Mycobacterium Marinum

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65Wikipedia, 33MalaCards
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Wikipedia:65 Mycobacterium marinum (formerly M. balnei) is a free-living bacterium, which causes opportunistic... more...

MalaCards: Mycobacterium Marinum, also known as mycobacterium marinum infection, is related to arthritis and tuberculosis. An important gene associated with Mycobacterium Marinum is IL8 (interleukin 8), and among its related pathways are Toll Comparative Pathway and NF-kappa B signaling pathway. The compounds cilomilast and n-tosyl-l-phenylalanine chloromethyl ketone have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and lymph node, and related mouse phenotypes are immune system and hematopoietic system.

Aliases & Classifications for Mycobacterium Marinum

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43NIH Rare Diseases, 62UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

mycobacterium marinum 43
mycobacterium marinum infection 43 62
fish tank granuloma 43
m. marinum 43


Related Diseases for Mycobacterium Marinum

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Mycobacterium Marinum:



Diseases related to mycobacterium marinum

Symptoms for Mycobacterium Marinum

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Drugs & Therapeutics for Mycobacterium Marinum

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Mycobacterium Marinum

Search NIH Clinical Center for Mycobacterium Marinum

Genetic Tests for Mycobacterium Marinum

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Anatomical Context for Mycobacterium Marinum

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33MalaCards
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MalaCards organs/tissues related to Mycobacterium Marinum:

33
Skin, Testes, Lymph node, T cells, Monocytes, Bone, Heart, Lung

Animal Models for Mycobacterium Marinum or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Mycobacterium Marinum:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.5TNF, FLOT1, IL8, CAMP, ARAF
2MP:00053977.2TNF, FLOT1, IL8, CAMP, ARAF

Publications for Mycobacterium Marinum

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52PubMed
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Articles related to Mycobacterium Marinum:

(show top 50)    (show all 404)
idTitleAuthorsYear
1
Increased Phagocytosis of Mycobacterium marinum Mutants Defective in Lipooligosaccharide Production: A STRUCTURE-ACTIVITY RELATIONSHIP STUDY. (24235141)
2014
2
Mycobacterium marinum infection in a case of psoriasis treated with antitumor necrosis factor I+ antibody detected by QuantiFERON(Ar) -TB test. (23675972)
2013
3
Comparative genome analysis of fish and human isolates of Mycobacterium marinum. (23728847)
2013
4
Invasive Mycobacterium marinum infection of the hand. (23971680)
2013
5
Revealing of Mycobacterium marinum transcriptome by RNA-seq. (24098731)
2013
6
Conserved mechanisms of Mycobacterium marinum pathogenesis within the environmental amoeba Acanthamoeba castellanii. (22247144)
2012
7
PPE38 modulates the innate immune response and is required for Mycobacterium marinum virulence. (22038915)
2012
8
Analysis of the immune response in infections of the goldfish (Carassius auratus L.) with Mycobacterium marinum. (22885635)
2012
9
Both phthiocerol dimycocerosates and phenolic glycolipids are required for virulence of Mycobacterium marinum. (22290144)
2012
10
Mycobacterium marinum causes a latent infection that can be reactivated by gamma irradiation in adult zebrafish. (23028333)
2012
11
Fatty acyl chains of Mycobacterium marinum lipooligosaccharides: structure, localization and acylation by PapA4 (MMAR_2343) protein. (21803773)
2011
12
Regioselective I8-hydroxylation of medium-chain n-alkanes and primary alcohols by CYP153 enzymes from Mycobacterium marinum and Polaromonas sp. strain JS666. (21837346)
2011
13
Structural analysis of an unusual bioactive N-acylated lipo-oligosaccharide LOS-IV in Mycobacterium marinum. (20964371)
2010
14
Transfer, stable maintenance and expression of the mycolactone polyketide megasynthase mls genes in a recombination-impaired Mycobacterium marinum. (19383681)
2009
15
Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis. (19636684)
2009
16
Local and disseminated infections caused by Mycobacterium marinum: an unusual cause of subcutaneous nodules. (18525435)
2008
17
Mycobacterium marinum infections in transplant recipients: case report and review of the literature. (18482202)
2008
18
Mycobacterium marinum presenting as large verrucous plaques on the lower extremity of a South Pacific Islander. (18689618)
2008
19
Identification of the lipooligosaccharide biosynthetic gene cluster from Mycobacterium marinum. (17302813)
2007
20
Identification of Mycobacterium marinum macrophage infection mutants. (16451826)
2006
21
Mycobacterium marinum, a further infectious agent associated with sarcoidosis: the polyetiology hypothesis. (16449013)
2006
22
Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous tuberculosis and is moderated by adaptive immunity. (17057088)
2006
23
Genotyping Mycobacterium ulcerans and Mycobacterium marinum by using mycobacterial interspersed repetitive units. (15716434)
2005
24
Simultaneous chronic cutaneous infection with Mycobacterium marinum and Nocardia asteroides. (15793529)
2005
25
Mycobacterium marinum infections in fish and humans in Israel. (15695698)
2005
26
Nostril infection due to Mycobacterium marinum in an immunocompetent host. (12587630)
2002
27
Strain variation in Mycobacterium marinum fish isolates. (12406715)
2002
28
Efficacy of oral minocycline and hyperthermic treatment in a case of atypical mycobacterial skin infection by Mycobacterium marinum. (12532049)
2002
29
Mycobacterium marinum infection in a lung transplant recipient. (11295588)
2001
30
Transformation and transposition of the genome of Mycobacterium marinum. (10685681)
2000
31
The Mycobacterium marinum G13 promoter is a strong sigma 70-like promoter that is expressed in Escherichia coli and mycobacteria species. (10361711)
1999
32
Picture of the month. Mycobacterium marinum facial abscess. (10323638)
1999
33
Recurrent, disseminated Mycobacterium marinum infection caused by the same genotypically defined strain in an immunocompromised patient. (10449508)
1999
34
Mycobacterium marinum: chronic and extensive infections of the lower limbs in south Pacific islanders. (9737045)
1998
35
Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens). (9009340)
1997
36
Application of the Etest to the antimicrobial susceptibility testing of Mycobacterium marinum clinical isolates. (9230386)
1997
37
Atypical mycobacterial infection caused by Mycobacterium marinum. (2304513)
1990
38
Osteomyelitis and synovitis produced by Mycobacterium marinum in a fisherman. (2254433)
1990
39
Mycobacterium marinum infection in a patient with cryptosporidiosis and the acquired immunodeficiency syndrome. (3203532)
1988
40
Swimming pool granulomas due to Mycobacterium marinum: an occupational hazard of lifeguards. (3391044)
1988
41
Synovial involvement by Mycobacterium marinum. A histopathological study of 25 culture-proven cases. (3241735)
1988
42
Mycobacterium marinum infections of the hand and wrist. Results of conservative treatment in twenty-four cases. (3356732)
1988
43
Multiplication of Mycobacterium marinum within phagolysosomes of murine macrophages. (3997252)
1985
44
Mycobacterium marinum infection in a 4-year-old child. (3987170)
1985
45
A co-operative numerical analysis of Mycobacterium gastri, Mycobacterium kansasii and Mycobacterium marinum. (745004)
1978
46
Sporotrichoid Mycobacterium marinum infection in diabetes. Chemotherapy with rifampin and ethambutol. (279836)
1978
47
Mycobacterium marinum infection. (1023872)
1976
48
Mycobacterium marinum in Gulf fishermen. (4709116)
1973
49
Tropical fish aquariums. A source of Mycobacterium marinum infections resembling sporotrichosis. (5466918)
1970
50
PREPATELLAR BURSITIS CAUSED BY MYCOBACTERIUM MARINUM (BALNEI); CASE REPORT, CLASSIFICATION, AND REVIEW OF THE LITERATURE. (14261813)
1965

Variations for Mycobacterium Marinum

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Expression for genes affiliated with Mycobacterium Marinum

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mycobacterium Marinum

Search GEO for disease gene expression data for Mycobacterium Marinum.

Pathways for genes affiliated with Mycobacterium Marinum

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50PathCards, 53QIAGEN, 60Thomson Reuters, 30KEGG, 55Reactome, 38NCBI BioSystems Database, 54R&D Systems
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Pathways related to Mycobacterium Marinum according to GeneCards/GeneDecks:

(show all 20)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Immune response MIF in innate immunity response60
9.5IL8, TNF
29.5TNF, IL8
3
Show member pathways
9.5TNF, IL8
4
Show member pathways
9.5TNF, IL8
59.5IL8, TNF
69.5IL8, TNF
79.5IL8, TNF
89.5TNF, IL8
9
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.5TNF, IL8
109.5IL8, TNF
119.5IL8, TNF
129.5IL8, TNF
139.5TNF, IL8
149.5IL8, TNF
159.5TNF, IL8
16
Show member pathways
Calcium signaling in the CD4+ TCR pathway38
9.5TNF, IL8
17
Show member pathways
IL-9 Signaling Pathway38
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway38
Immune response IL 9 signaling pathway60
9.4TNF, ARAF
189.3CAMP, TNF
199.0ARAF, IL8, TNF
20
Show member pathways
Transcription Receptor mediated HIF regulation60
Development CNTF receptor signaling60
Class IB PI3K non-lipid kinase events38
ErbB2/ErbB3 signaling events38
Development Growth hormone signaling via PI3K AKT and MAPK cascades60
Translation Regulation activity of EIF260
Regulation of lipid metabolism Insulin signaling generic cascades60
Transcription PPAR Pathway60
Cell adhesion PLAU signaling60
Translation Regulation activity of EIF4F60
8.6TNF, FLOT1, ARAF

Compounds for genes affiliated with Mycobacterium Marinum

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Sources:
45Novoseek, 61Tocris Bioscience, 29IUPHAR, 11DrugBank, 51PharmGKB, 3BitterDB, 24HMDB
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Compounds related to Mycobacterium Marinum according to GeneCards/GeneDecks:

(show top 50)    (show all 70)
idCompoundScoreTop Affiliating Genes
1cilomilast459.9IL8, TNF
2n-tosyl-l-phenylalanine chloromethyl ketone459.9IL8, TNF
3taurine chloramine459.9IL8, TNF
4gabexate mesilate459.9IL8, TNF
5toxin-1459.9IL8, TNF
6ulinastatin459.9TNF, IL8
7mip 1alpha459.9TNF, IL8
8gold sodium thiomalate459.9IL8, TNF
9aebsf459.9IL8, TNF
10il-12459.9IL8, TNF
115 aminosalicylic acid459.9TNF, IL8
12staurosporin459.9IL8, TNF
13imiquimod45 61 29 1112.9TNF, IL8
14tpck459.9TNF, IL8
15groalpha459.9IL8, TNF
16go 697645 6110.9IL8, TNF
17triptolide459.8TNF, IL8
18gm-csf45 2910.8IL8, TNF
19budesonide45 51 1111.8TNF, IL8
20ciglitazone45 2910.8TNF, IL8
21parthenolide45 310.8TNF, IL8
22hbd2459.8IL8, CAMP
23sulfasalazine29 45 51 1112.8IL8, TNF
248-isoprostane459.8IL8, TNF
25fluticasone propionate45 51 61 1112.8IL8, TNF
26ns 39845 6110.8TNF, IL8
27polyinosinic-polycytidylic acid459.7TNF, IL8
28etanercept45 51 1111.7IL8, TNF
29salbutamol45 51 29 24 1113.7CAMP, IL8
30poly(i-c)459.7TNF, IL8
31il 10459.6TNF, IL8
32diphenyleneiodonium459.6TNF, IL8
33tarc459.6IL8, TNF
34peptidoglycan45 2910.5TNF, IL8
35ccl345 2910.5TNF, IL8
36n-formylmethionyl-leucylphenylalanine459.4TNF, IL8
37polymyxin b459.3CAMP, IL8, TNF
38lipoteichoic acid459.3CAMP, IL8, TNF
39rolipram45 61 2911.3IL8, TNF, CAMP
40pentoxifylline45 1110.3CAMP, TNF, IL8
41endotoxin459.3TNF, IL8, CAMP
42fmlp459.3CAMP, IL8, TNF
43butyrate459.3CAMP, IL8, TNF
44histamine45 29 2411.3IL8, CAMP, TNF
45pd 98,059459.3TNF, IL8, CAMP
46actinomycin d459.2IL8, TNF, CAMP
47genistein45 29 61 3 24 1114.2IL8, CAMP, TNF
48erythromycin45 3 51 1112.2IL8, ARAF
49pge2459.1IL8, CAMP, TNF
50serine458.6ARAF, IL8, CAMP, TNF

GO Terms for genes affiliated with Mycobacterium Marinum

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Sources:
16Gene Ontology
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Cellular components related to Mycobacterium Marinum according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1membrane raftGO:0451219.1FLOT1, TNF

Biological processes related to Mycobacterium Marinum according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of peptidyl-serine phosphorylationGO:0331389.4ARAF, TNF
2embryonic digestive tract developmentGO:0485669.4IL8, TNF
3calcium-mediated signalingGO:0197229.2IL8, TNF

Molecular functions related to Mycobacterium Marinum according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.5ARAF, CAMP, IL8, FLOT1, TNF

Products for genes affiliated with Mycobacterium Marinum

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Sources for Mycobacterium Marinum

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet