MCID: MYL001
MIFTS: 51

Myelitis malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Myelitis

Aliases & Descriptions for Myelitis:

Name: Myelitis 12 50 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:322
MeSH 42 D009187
NCIt 47 C26832
UMLS 69 C0026975

Summaries for Myelitis

Disease Ontology : 12 A spinal cord disease that is characterized by inflammation of the white matter or gray matter of the spinal cord.

MalaCards based summary : Myelitis is related to hepatitis and meningitis. An important gene associated with Myelitis is AQP4 (Aquaporin 4), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Mitoxantrone and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and lung, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and hematopoietic system

Wikipedia : 71 Myelitis involves the infection or the inflammation of the white matter or gray matter of the spinal... more...

Related Diseases for Myelitis

Diseases related to Myelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 396)
id Related Disease Score Top Affiliating Genes
1 hepatitis 30.2 IL10 IL6 TNF
2 meningitis 30.1 CXCL8 IL6 TNF
3 neuropathy 30.0 CXCL8 IL6 TNF
4 tuberculosis 29.5 IL10 IL17A IL6 TNF
5 dermatitis herpetiformis 29.3 IL17A TNF
6 crest syndrome 29.3 AQP4 MBP
7 colon adenocarcinoma 29.0 CXCL8 IL10 IL6 TNF
8 pulmonary eosinophilia 29.0 CXCL8 IL10 IL6 TNF
9 rheumatoid arthritis 28.7 CXCL8 HLA-DPB1 IL10 IL17A IL6 TNF
10 transverse myelitis 12.4
11 acute flaccid myelitis 12.2
12 acute transverse myelitis 12.1
13 idiopathic acute transverse myelitis 12.0
14 secondary acute transverse myelitis 11.9
15 radiation myelitis 11.9
16 neuromyelitis optica 11.4
17 foix-alajouanine syndrome 11.3
18 antiphospholipid syndrome 11.1
19 spinal cord disease 10.8
20 encephalitis 10.5
21 acute disseminated encephalomyelitis 10.4
22 tropical spastic paraparesis 10.3
23 stiff-person syndrome 10.3
24 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.3 IL6 TNF
25 supraumbilical midabdominal raphe and facial cavernous hemangiomas 10.3 APOH IL6
26 systemic lupus erythematosus 10.3
27 lupus erythematosus 10.3
28 dyslexia 5 10.3 IL6 TNF
29 aortic atherosclerosis 10.3 IL6 TNF
30 degenerative disc disease 10.3 IL6 TNF
31 pyridoxal 5'-phosphate-dependent epilepsy 10.2 IL10 TNF
32 atherosclerosis 10.2 APOH IL6
33 ureter inverted papilloma 10.2 IL10 IL6
34 unilateral multicystic dysplastic kidney 10.2 IL6 TNF
35 tubular renal disease-cardiomyopathy syndrome 10.2 IL10 TNF
36 oculomotor nerve paralysis 10.2 CXCL8 IL6
37 meningoencephalitis 10.2
38 nguyen syndrome 10.2 IL10 IL17A
39 common peroneal nerve lesion 10.2 CXCL8 IL6
40 lagophthalmos 10.2 IL10 TNF
41 multiple vertebral anomalies unusual facies 10.2 IL10 TNF
42 swine influenza 10.2 IL6 TNF
43 primary non-gestational choriocarcinoma of ovary 10.2 CXCL8 IL17A
44 drug dependence 10.2 IL6 TNF
45 childhood brainstem astrocytoma 10.2 AQP4 MBP
46 endosalpingiosis 10.2 IL10 TNF
47 uterine corpus cancer 10.2 APOH AQP4 TNF
48 psychotic disorder 10.2 CXCL8 IL6
49 autoimmune disease of central nervous system 10.2 APOH IL6 TNF
50 severe combined immunodeficiency, t cell-negative, b-cell/natural killer-cell positive 10.2 IL10 TNF

Graphical network of the top 20 diseases related to Myelitis:



Diseases related to Myelitis

Symptoms & Phenotypes for Myelitis

GenomeRNAi Phenotypes related to Myelitis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.32 APOH CXCL8 IL10 IL17A TNF
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.32 APOH CXCL8 IL10 IL17A TNF

MGI Mouse Phenotypes related to Myelitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.92 MBP AQP4 MMP2 IL10 TNF IL17A
2 homeostasis/metabolism MP:0005376 9.91 APOH MBP AQP4 MMP2 IL10 TNF
3 digestive/alimentary MP:0005381 9.85 AQP4 IL10 TNF IL17A IL6 IL9
4 immune system MP:0005387 9.76 MBP AQP4 MMP2 IL10 TNF IL17A
5 respiratory system MP:0005388 9.43 AQP4 MMP2 IL10 TNF IL17A IL6
6 vision/eye MP:0005391 9.1 MBP AQP4 MMP2 IL10 TNF IL6

Drugs & Therapeutics for Myelitis

Drugs for Myelitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 158)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Mitoxantrone Approved, Investigational Phase 4 65271-80-9 4212
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 50-24-8 5755
4
Interferon beta-1a Approved, Investigational Phase 4,Phase 2 145258-61-3 6438354
5
Zinc Approved Phase 4 7440-66-6 32051 23994
6 Zinc sulfate Approved Phase 4 7733-02-0
7
Edetic Acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 60-00-4, 62-33-9 6049
8
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
9
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
10
Mycophenolic acid Approved Phase 4 24280-93-1 446541
11
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
12
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
13
Phenol Approved, Experimental Phase 4 108-95-2 996
14 Antibodies Phase 4,Phase 3,Phase 2,Phase 1
15 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1
16 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
17 Analgesics Phase 4
18 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1
19 Topoisomerase Inhibitors Phase 4
20 Antiemetics Phase 4,Phase 3,Phase 1
21 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1
22 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 1
23 Autonomic Agents Phase 4,Phase 3,Phase 1
24 Gastrointestinal Agents Phase 4,Phase 3,Phase 1,Phase 2
25 glucocorticoids Phase 4,Phase 3,Phase 1
26 Hormone Antagonists Phase 4,Phase 3,Phase 1
27 Hormones Phase 4,Phase 3,Phase 1
28 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 1
29 Methylprednisolone acetate Phase 4,Phase 3,Phase 1,Phase 2
30 Methylprednisolone Hemisuccinate Phase 4,Phase 3,Phase 1,Phase 2
31 Neuroprotective Agents Phase 4,Phase 3,Phase 1
32 Prednisolone acetate Phase 4,Phase 3,Phase 1,Phase 2
33 Prednisolone hemisuccinate Phase 4,Phase 3,Phase 1,Phase 2
34 Prednisolone phosphate Phase 4,Phase 3,Phase 1,Phase 2
35 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
36 Adjuvants, Immunologic Phase 4,Phase 1,Phase 2
37 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Early Phase 1
38 Antiviral Agents Phase 4,Phase 2,Phase 3,Early Phase 1
39 Interferon-beta Phase 4,Phase 2
40 interferons Phase 4,Phase 2
41 Micronutrients Phase 4
42 Trace Elements Phase 4
43 Anticoagulants Phase 4,Phase 3,Phase 2
44 Antidotes Phase 4,Phase 3,Phase 2
45 Calcium, Dietary Phase 4,Phase 3,Phase 2
46 Chelating Agents Phase 4,Phase 3,Phase 2
47 Iron Chelating Agents Phase 4,Phase 3,Phase 2
48 Pentetic Acid Phase 4,Phase 3,Phase 2
49 Fibrinolytic Agents Phase 4,Phase 3,Phase 2
50 PENTA Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 221)
id Name Status NCT ID Phase
1 Immunogenicity of 1 or 2 Doses of bOPV in Chilean Infants Primed With IPV Vaccine Unknown status NCT01841671 Phase 4
2 Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders Unknown status NCT02021825 Phase 4
3 Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis Completed NCT00179478 Phase 4
4 A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease) Completed NCT00304291 Phase 4
5 Oral Corticotherapy in Megadoses to Treat Multiple Sclerosis During Relapse Completed NCT00753792 Phase 4
6 Immunogenicity of Monovalent Type 2 Oral Poliovirus Vaccine Completed NCT02643368 Phase 4
7 Intestinal and Humoral Immunity of Sequential Polio Vaccination Schedules Completed NCT02412514 Phase 4
8 Polio End-game Strategies - Poliovirus Type 2 Challenge Study Completed NCT02189811 Phase 4
9 Study of IMOVAX POLIO® Subcutaneous as a Booster Vaccine in Pre-school Age Children in Japan Completed NCT02005536 Phase 4
10 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4
11 Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine Completed NCT01831050 Phase 4
12 IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi. Completed NCT01695798 Phase 4
13 Zinc and/or Probiotic Supplementation of Rotavirus and Oral Polio Virus Vaccines Completed NCT01616693 Phase 4
14 Sequential Inactivated Poliomyelitis Vaccine Followed by Oral Poliomyelitis Vaccine Versus Oral Poliomyelitis Vaccine Completed NCT01475539 Phase 4
15 A Safety Study of IMOVAX Polio Vaccine in Selected Cities in China Completed NCT01278433 Phase 4
16 A Study of the Safety of IMOVAX Polio™ in China Completed NCT01244464 Phase 4
17 Study to Evaluate the Safety of Co-administration of GSK Biologicals' Poliorix and Infanrix in Healthy Children in Russia Completed NCT01094171 Phase 4
18 Antibody Persistence to REVAXIS or DT Polio and Immune Response to TETRAVAC-ACELLULAIRE Completed NCT01546909 Phase 4
19 Comparison of Immunogenicity and Reactogenicity of INFANRIX™ HEXA and HEXAVAC™ Vaccines as a Primary Vaccination Course Completed NCT01457547 Phase 4
20 Regulatory Post-Marketing Surveillance Study for TETRAXIM™ Completed NCT01437423 Phase 4
21 Study to Evaluate Antibody Persistence in Children Previously Vaccinated With Infanrix Hexa™ or Infanrix-IPV/Hib™ Completed NCT01358825 Phase 4
22 Immunogenicity and Safety of Booster Dose of BoostrixTM Polio Vaccine in Previously Boosted Adults Completed NCT01323959 Phase 4
23 Immunogenicity and Safety of TETRAXIM™ Given as a Booster Dose at 4 to 6 Years of Age Completed NCT01031303 Phase 4
24 Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants Completed NCT00753649 Phase 4
25 Safety and Immunogenicity of a Booster Dose of GSK Biological's Boostrix-Polio Vaccine Completed NCT00635128 Phase 4
26 Study of a New Formulation of DTPa-HBV-IPV/Hib Vaccine Administered as a Booster Dose to 18-23 Months Old Children Completed NCT00611559 Phase 4
27 Immunogenicity and Safety Study of a Booster Dose (5th) of Diphteria-Tetanus-Pertussis-Polio Vaccine Completed NCT00514059 Phase 4
28 Assess the Safety & Reactogenicity of DTPa-IPV/Hib Vaccine Administered at 3, 4, 5 & 18 Mths of Age, in Healthy Infants Completed NCT00325156 Phase 4
29 Post-marketing Evaluation of Reactions Following Receipt of Recommended Adolescent Pertussis Vaccine Completed NCT00304265 Phase 4
30 Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand Completed NCT00255021 Phase 4
31 Evaluation of Immunogenicity and Safety of a Booster Dose of Infanrix Hexa™ in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Recruiting NCT02853929 Phase 4
32 Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Recruiting NCT02422264 Phase 4
33 Fractional Inactivated Poliovirus Vaccine Booster and Rotavirus Study Active, not recruiting NCT02847026 Phase 4
34 To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan Active, not recruiting NCT01908114 Phase 4
35 Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients Enrolling by invitation NCT02809079 Phase 4
36 A Study to Evaluate the Safety and Immunogenicity of Monovalent OPV2 in Children Aged 1 to 5 Years in Lithuania Not yet recruiting NCT02582255 Phase 4
37 A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age Not yet recruiting NCT02580201 Phase 4
38 Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event. Withdrawn NCT00037115 Phase 4
39 Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone Unknown status NCT00004645 Phase 3
40 Randomized Clinical Trial to Evaluate Immunogenicity and Safety in Mexicans Newborns Unknown status NCT01870206 Phase 3
41 Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) Unknown status NCT01343355 Phase 2, Phase 3
42 Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801 Completed NCT01604746 Phase 3
43 Randomized Controlled Trial for Immunogenicity and Safety Evaluation of Bivalent Types 1 and 3 Oral Poliovirus Vaccine Completed NCT02785705 Phase 3
44 Immunogenicity and Safety of Liquid Bivalent Oral Poliomyelitis Vaccine Completed NCT02434770 Phase 3
45 Immunogenicity of Intramuscular Inactivated Poliovirus Vaccine Completed NCT02291263 Phase 3
46 The Immunogenicity and Safety of Live Attenuated Poliomyelitis Vaccine (Human Diploid Cell) Completed NCT02231632 Phase 2, Phase 3
47 Immunogenicity of Inactivated and Live Polio Vaccines Completed NCT01813604 Phase 3
48 The Clinical Trial Protocol for the Inactivated Poliomyelitis Vaccine Made From Sabin Strains(Sabin IPV) Completed NCT01510366 Phase 3
49 Study of SP059 Given Subcutaneously as a Three-dose Primary and Booster Vaccination in Infants in Japan Completed NCT01389687 Phase 3
50 Immunogenicity and Safety of Booster Dose of PoliorixTM Vaccine in Previously Vaccinated Toddlers Completed NCT01323647 Phase 3

Search NIH Clinical Center for Myelitis

Cochrane evidence based reviews: myelitis

Genetic Tests for Myelitis

Anatomical Context for Myelitis

MalaCards organs/tissues related to Myelitis:

39
Spinal Cord, Brain, Lung, Bone, Bone Marrow, Breast, B Cells

Publications for Myelitis

Articles related to Myelitis:

(show top 50) (show all 927)
id Title Authors Year
1
Acute myelitis resembling human T-lymphotropic virus type 1-associated myelopathy presenting as high-signal-intensity long cord lesions on T2-weighted magnetic resonance images combined with lymphoma-type adult T-cell leukemia/lymphoma. ( 27817856 )
2017
2
Recall radiation myelitis after stereotactic radiation and dabrafenib in metastatic melanoma. ( 27830981 )
2017
3
Comorbidity of narcolepsy with cataplexy and transverse myelitis: aA common autoimmune background? A case report. ( 28449899 )
2017
4
Acute flaccid myelitis associated with enterovirus-D68 infection in an otherwise healthy child. ( 28081720 )
2017
5
Chronic neuropathic pain severity is determined by lesion level in aquaporin 4-antibody-positive myelitis. ( 27884934 )
2017
6
Short segment myelitis as a first manifestation of neuromyelitis optica spectrum disorders. ( 28067584 )
2017
7
A Rare Infectious Cause of Transverse Myelitis. ( 28004628 )
2017
8
Etiologic spectrum and functional outcome of the acute inflammatory myelitis. ( 28074391 )
2017
9
Toxocara canis-Associated Myelitis with Eosinophilic Pneumonia. ( 27358582 )
2016
10
Serological prevalence of celiac disease in Brazilian population of multiple sclerosis, neuromyelitis optica and myelitis. ( 27645359 )
2016
11
Myelitis in systemic lupus erythematosus: clinical characteristics and effect in accrual damage. A single-center experience. ( 27480991 )
2016
12
Transverse myelitis-like presentation of methanol intoxication: A case report and review of the literature. ( 27707395 )
2016
13
Cervical Myelitis Presenting as Occipital Neuralgia. ( 28025377 )
2016
14
Transverse Myelitis and Neuromyelitis Optica Spectrum Disorders. ( 27616312 )
2016
15
Transverse myelitis. ( 26882855 )
2016
16
Cervical spinal cord atrophy in NMOSD without a history of myelitis or MRI-visible lesions. ( 27144215 )
2016
17
Recognition and Management of Acute Flaccid Myelitis in Children. ( 26621554 )
2016
18
Longitudinally extensive transverse myelitis: A retrospective analysis of sixty-four patients at tertiary care center of North-West India. ( 27348743 )
2016
19
Parainfectious longitudinally extensive transverse myelitis associated with varicella-zoster virus. ( 27157526 )
2016
20
Longitudinal extensive transverse myelitis and Zika virus: A diagnostic challenge in a hospital in Colombia. ( 27776956 )
2016
21
Differentiation of neuromyelitis optica spectrum disorders from ultra-longitudinally extensive transverse myelitis in a cohort of Chinese patients. ( 26857502 )
2016
22
Transverse myelitis associated with heroin and cannabis abuse: a new issue from the past. ( 27003705 )
2016
23
A pediatric patient of hemorrhagic acute transverse myelitis. ( 27686688 )
2016
24
Longitudinal extensive transverse myelitis with cervical epidural haematoma following dengue virus infection. ( 26900103 )
2016
25
Elevated Lipid Profiles in Patients with Acute Transverse Myelitis. ( 26949935 )
2016
26
Teaching NeuroImages: Longitudinally extensive transverse myelitis in MELAS. ( 26810428 )
2016
27
An Unusual Case of Myelitis with Myositis. ( 27437283 )
2016
28
Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014. ( 27434186 )
2016
29
Viral load and ganciclovir (GCV) concentration in cerebrospinal fluid of patients successfully treated with GCV or valGCV for human herpesvirus 6 encephalitis/myelitis following umbilical cord blood transplantation. ( 27459097 )
2016
30
Successful management of methicillin-resistant Staphylococcus aureus bacteremia complicated with diffuse myelitis. ( 27464005 )
2016
31
Concomitant Guillain Barre Syndrome and Transverse Myelitis as Initial Neuropsychiatric Manifestation in a Case of Lupus: A Diagnostic Quandary. ( 27242943 )
2016
32
Poster 463 Unexpected Transverse Myelitis after Dinutuximab Therapy for Relapsed Neuroblastoma: A Case Report. ( 27673209 )
2016
33
Evaluation and management of longitudinally extensive transverse myelitis: a guide for radiologists. ( 27450408 )
2016
34
Leprous ganglionitis and myelitis. ( 27218117 )
2016
35
Linear lesions may assist early diagnosis of neuromyelitis optica and longitudinally extensive transverse myelitis, two subtypes of NMOSD. ( 26723980 )
2016
36
Post-Herpes zoster myelitis in a very old patient: A complication not to be missed. ( 27440114 )
2016
37
Neuromyelitis optica spectrum initially diagnosed as antiphospholipid antibody myelitis. ( 26810544 )
2016
38
An unusual case of acute transverse myelitis caused by HSV-1 infection. ( 27419072 )
2016
39
Acute myelitis due to Zika virus infection. ( 26946926 )
2016
40
A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient. ( 27883372 )
2016
41
Hemorrhagic Longitudinally Extensive Transverse Myelitis. ( 27847660 )
2016
42
Rehabilitation of a patient with overlap of acute transverse myelitis and Bickerstaff's brainstem encephalitis: a case report. ( 28053734 )
2016
43
Acute transverse myelitis of the cervical spine secondary to psoas abscess. ( 27756229 )
2016
44
Transverse Myelitis as an Unusual Complication of Dengue Fever. ( 27956656 )
2016
45
Myelitis: A Rare Neurological Complication of Herpes Zoster. ( 27904197 )
2016
46
Idiopathic Transverse Myelitis Mimicking an Intramedullary Spinal Cord Tumor. ( 27672469 )
2016
47
Acute myelitis by human herpes virus 7 in an HIV-infected patient. ( 26906233 )
2016
48
Extensive myelitis revealing common variable immunodeficiency. ( 27374860 )
2016
49
Acute Transverse Myelitis and Nicolau Syndrome after Benzathine Penicillin Injection. ( 27762530 )
2016
50
Amphiphysin-positive paraneoplastic myelitis and stiff-person syndrome. ( 27734022 )
2016

Variations for Myelitis

Expression for Myelitis

Search GEO for disease gene expression data for Myelitis.

Pathways for Myelitis

Pathways related to Myelitis according to GeneCards Suite gene sharing:

(show top 50) (show all 51)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.9 CXCL8 HLA-DPB1 IL10 IL17A IL6 IL9
2
Show member pathways
13.42 CXCL8 IL10 IL17A IL6 IL9 TNF
3
Show member pathways
13.3 CXCL8 IL10 IL17A IL6 IL9 TNF
4
Show member pathways
13.21 CXCL8 IL10 IL17A IL6 IL9 TNF
5
Show member pathways
13.21 CXCL8 HLA-DPB1 IL10 IL17A IL6 IL9
6
Show member pathways
12.69 CXCL8 HLA-DPB1 IL6 TNF
7
Show member pathways
12.61 CXCL8 HLA-DPB1 IL10 IL17A IL6 IL9
8
Show member pathways
12.54 HLA-DPB1 IL10 IL17A IL6 TNF
9
Show member pathways
12.53 IL10 IL17A IL6 MMP2 TNF
10
Show member pathways
12.37 IL10 IL17A IL6 IL9 TNF
11
Show member pathways
12.29 CXCL8 IL17A IL6 TNF
12 12.19 HLA-DPB1 IL10 IL6 TNF
13
Show member pathways
12.17 CXCL8 IL6 TNF
14
Show member pathways
12.12 IL10 IL6 IL9
15
Show member pathways
12.09 CXCL8 IL6 TNF
16 12.09 AQP4 CXCL8 IL10 IL6 TNF
17 12.08 IL6 MMP2 TNF
18 11.93 IL10 IL6 TNF
19
Show member pathways
11.92 IL10 IL17A IL6 TNF
20 11.88 CXCL8 IL6 MMP2 TNF
21 11.88 AQP4 CXCL8 IL6 MBP TNF
22 11.86 CXCL8 IL10 IL6 TNF
23 11.84 HLA-DPB1 IL6 TNF
24
Show member pathways
11.82 CXCL8 IL17A IL6
25 11.75 IL10 IL17A IL9 TNF
26 11.72 IL10 IL6 TNF
27 11.72 CXCL8 IL10 IL6 TNF
28 11.68 IL10 IL6 TNF
29 11.65 CXCL8 IL6 MMP2
30
Show member pathways
11.64 CXCL8 IL10 IL17A IL6 IL9 TNF
31 11.62 CXCL8 IL6 MMP2 TNF
32
Show member pathways
11.61 CXCL8 IL6 MMP2 TNF
33 11.61 CXCL8 HLA-DPB1 IL17A IL6 TNF
34 11.57 CXCL8 IL6 MMP2
35 11.56 CXCL8 IL6 TNF
36 11.53 IL6 MMP2 TNF
37 11.49 IL6 MMP2 TNF
38 11.45 CXCL8 IL10 IL6 TNF
39 11.42 CXCL8 IL10 IL6 TNF
40 11.35 IL10 IL6 TNF
41 11.34 IL10 IL6 TNF
42 11.32 CXCL8 IL6 MMP2
43 11.26 IL10 IL6 TNF
44 11.17 IL17A IL6 IL9 TNF
45 11.16 CXCL8 IL10 IL17A IL6 MMP2 TNF
46 11.12 IL10 IL9
47 11.08 CXCL8 TNF
48 11.03 IL6 TNF
49 11.02 CXCL8 IL6 TNF
50 10.86 IL6 IL9

GO Terms for Myelitis

Cellular components related to Myelitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 APOH CXCL8 IL10 IL17A IL6 IL9
2 external side of plasma membrane GO:0009897 9.46 AQP4 IL17A IL6 TNF
3 extracellular space GO:0005615 9.23 APOH CXCL8 IL10 IL17A IL6 IL9

Biological processes related to Myelitis according to GeneCards Suite gene sharing:

(show all 24)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.71 IL10 IL6 TNF
2 cellular response to interleukin-1 GO:0071347 9.63 CXCL8 IL17A IL6
3 negative regulation of mitotic cell cycle GO:0045930 9.62 IL10 TNF
4 negative regulation of interleukin-6 production GO:0032715 9.61 IL10 TNF
5 positive regulation of osteoclast differentiation GO:0045672 9.61 IL17A TNF
6 response to glucocorticoid GO:0051384 9.61 IL10 IL6 TNF
7 positive regulation of interleukin-6 secretion GO:2000778 9.6 IL17A MBP
8 defense response to protozoan GO:0042832 9.59 IL10 IL6
9 embryonic digestive tract development GO:0048566 9.58 CXCL8 TNF
10 positive regulation of chemokine production GO:0032722 9.58 IL6 TNF
11 negative regulation of growth of symbiont in host GO:0044130 9.57 IL10 TNF
12 cellular response to hepatocyte growth factor stimulus GO:0035729 9.56 IL10 IL6
13 cellular response to lipopolysaccharide GO:0071222 9.56 CXCL8 IL10 IL6 TNF
14 response to molecule of bacterial origin GO:0002237 9.55 CXCL8 IL10
15 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.52 IL10 TNF
16 negative regulation of lipid storage GO:0010888 9.51 IL6 TNF
17 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.49 IL10 MBP
18 endothelial cell apoptotic process GO:0072577 9.48 IL10 TNF
19 inflammatory response GO:0006954 9.43 CXCL8 IL10 IL17A IL6 IL9 TNF
20 negative regulation of cytokine secretion involved in immune response GO:0002740 9.4 IL10 TNF
21 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.37 IL6 TNF
22 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.33 IL10 MMP2 TNF
23 receptor biosynthetic process GO:0032800 9.32 IL10 TNF
24 immune response GO:0006955 9.23 CXCL8 HLA-DPB1 IL10 IL17A IL6 IL9

Molecular functions related to Myelitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.13 IL10 IL6 IL9
2 cytokine activity GO:0005125 9.1 CXCL8 IL10 IL17A IL6 IL9 TNF

Sources for Myelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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