MCID: MYL001
MIFTS: 48

Myelitis

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Myelitis

MalaCards integrated aliases for Myelitis:

Name: Myelitis 12 50 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:322
MeSH 42 D009187
NCIt 47 C26832
UMLS 69 C0026975

Summaries for Myelitis

Disease Ontology : 12 A spinal cord disease that is characterized by inflammation of the white matter or gray matter of the spinal cord.

MalaCards based summary : Myelitis is related to systemic lupus erythematosus and toxoplasmosis. An important gene associated with Myelitis is AQP4 (Aquaporin 4), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Allograft rejection. The drugs Mitoxantrone and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and t cells, and related phenotypes are hematopoietic system and immune system

Wikipedia : 72 Myelitis involves the infection or the inflammation of the white matter or gray matter of the spinal... more...

Related Diseases for Myelitis

Diseases related to Myelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 324)
id Related Disease Score Top Affiliating Genes
1 systemic lupus erythematosus 30.7 APOH HLA-DPB1 IL17A IL6 TNF
2 toxoplasmosis 30.2 IL6 TNF
3 influenza 30.0 CCL11 MMP2
4 primary biliary cirrhosis 29.9 IL6 TNF
5 vogt-koyanagi-harada disease 29.8 IL6 TNF
6 colon adenocarcinoma 29.5 CCL11 IL6 TNF
7 lymphoma 29.3 APOH IL17A IL6 TNF
8 rheumatoid arthritis 28.9 HLA-DPB1 IL17A IL6 TNF
9 ulcerative colitis 28.4 AQP4 IL6 MBP TNF
10 malaria 28.2 CCL11 IL17A IL6 IL9 TNF
11 transverse myelitis 12.4
12 acute flaccid myelitis 12.2
13 acute transverse myelitis 12.0
14 idiopathic acute transverse myelitis 12.0
15 secondary acute transverse myelitis 11.9
16 radiation myelitis 11.9
17 neuromyelitis optica 11.4
18 foix-alajouanine syndrome 11.3
19 antiphospholipid syndrome 11.1
20 spinal cord disease 10.7
21 thyrotoxic periodic paralysis 10.7
22 lupus - neurological sequelae 10.7
23 paresthesia 10.7
24 psychotic disorder 10.7 CCL11 IL6
25 asphyxia neonatorum 10.6 APOH IL6
26 smarca4-deficient sarcoma of thorax 10.6 IL6 TNF
27 aortic arch interruption 10.6 IL6 TNF
28 cutaneous leishmaniasis 10.6 IL6 TNF
29 spirillary rat-bite fever 10.6 IL6 TNF
30 dyslexia 5 10.6 IL6 TNF
31 epstein-barr virus hepatitis 10.6 IL6 TNF
32 encephalitis 10.5
33 scrotal carcinoma 10.5 IL6 TNF
34 anencephaly and spina bifida x-linked 10.5 IL6 TNF
35 antigen-peptide-transporter 2 deficiency 10.5 IL6 TNF
36 papilledema 10.5 IL6 TNF
37 ethmoid sinus adenocarcinoma 10.5 IL6 TNF
38 upper gum cancer 10.5 IL6 TNF
39 potato nose 10.5 IL6 TNF
40 tarsal tunnel syndrome 10.5 IL9 TNF
41 bipolar i disorder 10.5 IL6 TNF
42 biemond syndrome 10.5 HLA-DPB1 TNF
43 lymphocytic colitis 10.5 IL6 TNF
44 pasteurellosis 10.5 IL6 TNF
45 mosaic trisomy 1 10.5 HLA-DPB1 TNF
46 tinea favosa 10.5 IL6 TNF
47 indolent myeloma 10.5 IL6 TNF
48 stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features 10.5 IL6 TNF
49 cicatricial lagophthalmos 10.4 IL6 TNF
50 malignant gastric granular cell tumor 10.4 IL17A IL6

Graphical network of the top 20 diseases related to Myelitis:



Diseases related to Myelitis

Symptoms & Phenotypes for Myelitis

MGI Mouse Phenotypes related to Myelitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.91 AQP4 CCL11 IL17A IL6 IL9 MBP
2 immune system MP:0005387 9.81 IL9 MBP MMP2 MOG TNF AQP4
3 respiratory system MP:0005388 9.43 AQP4 CCL11 IL17A IL6 MMP2 TNF
4 vision/eye MP:0005391 9.1 AQP4 IL6 MBP MMP2 MOG TNF

Drugs & Therapeutics for Myelitis

Drugs for Myelitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 157)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Mitoxantrone Approved, Investigational Phase 4 65271-80-9 4212
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 50-24-8 5755
4
Interferon beta-1a Approved, Investigational Phase 4,Phase 2 145258-61-3 6438354
5
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
6
Phenol Approved, Experimental Phase 4 108-95-2 996
7
Zinc Approved Phase 4 7440-66-6 32051 23994
8 Zinc sulfate Approved Phase 4 7733-02-0
9
Edetic Acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 60-00-4, 62-33-9 6049
10
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
11
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
12
Mycophenolic acid Approved Phase 4 24280-93-1 446541
13
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
14 Antibodies Phase 4,Phase 3,Phase 2,Phase 1
15 Antibodies, Blocking Phase 4
16 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1
17 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
18 Analgesics Phase 4
19 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1
20 Topoisomerase Inhibitors Phase 4
21 Antiemetics Phase 4,Phase 3,Phase 1
22 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1
23 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 1
24 Autonomic Agents Phase 4,Phase 3,Phase 1
25 Gastrointestinal Agents Phase 4,Phase 3,Phase 1,Phase 2
26 glucocorticoids Phase 4,Phase 3,Phase 1
27 Hormone Antagonists Phase 4,Phase 3,Phase 1
28 Hormones Phase 4,Phase 3,Phase 1
29 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 1
30 Methylprednisolone acetate Phase 4,Phase 3,Phase 1,Phase 2
31 Methylprednisolone Hemisuccinate Phase 4,Phase 3,Phase 1,Phase 2
32 Neuroprotective Agents Phase 4,Phase 3,Phase 1
33 Prednisolone acetate Phase 4,Phase 3,Phase 1,Phase 2
34 Prednisolone hemisuccinate Phase 4,Phase 3,Phase 1,Phase 2
35 Prednisolone phosphate Phase 4,Phase 3,Phase 1,Phase 2
36 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Adjuvants, Immunologic Phase 4,Phase 1,Phase 2
38 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Early Phase 1
39 Antiviral Agents Phase 4,Phase 2,Phase 3,Early Phase 1
40 Interferon-beta Phase 4,Phase 2
41 interferons Phase 4,Phase 2
42 Anti-Bacterial Agents Phase 4
43 Polymyxin B Phase 4
44 Polymyxins Phase 4
45 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
46 Micronutrients Phase 4
47 Trace Elements Phase 4
48 Anticoagulants Phase 4,Phase 3,Phase 2
49 Antidotes Phase 4,Phase 3,Phase 2
50 Calcium, Dietary Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 227)

id Name Status NCT ID Phase Drugs
1 Immunogenicity of 1 or 2 Doses of bOPV in Chilean Infants Primed With IPV Vaccine Unknown status NCT01841671 Phase 4
2 Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders Unknown status NCT02021825 Phase 4 Mitoxantrone
3 Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis Completed NCT00179478 Phase 4 interferon beta 1a 30 ug IM once weekly
4 A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease) Completed NCT00304291 Phase 4 Mitoxantrone
5 Oral Corticotherapy in Megadoses to Treat Multiple Sclerosis During Relapse Completed NCT00753792 Phase 4 methylprednisolone;methylprednisolone;Placebo
6 Immunogenicity of Monovalent Type 2 Oral Poliovirus Vaccine Completed NCT02643368 Phase 4
7 A Study to Evaluate the Safety and Immunogenicity of Monovalent OPV2 in Children Aged 1 to 5 Years in Lithuania Completed NCT02582255 Phase 4
8 A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age Completed NCT02580201 Phase 4
9 Intestinal and Humoral Immunity of Sequential Polio Vaccination Schedules Completed NCT02412514 Phase 4
10 Polio End-game Strategies - Poliovirus Type 2 Challenge Study Completed NCT02189811 Phase 4
11 Study of IMOVAX POLIO® Subcutaneous as a Booster Vaccine in Pre-school Age Children in Japan Completed NCT02005536 Phase 4
12 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4 IPV IM Needle;IPV ID Needle;IPV IM Device;IPV ID Device
13 Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine Completed NCT01831050 Phase 4
14 IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi. Completed NCT01695798 Phase 4
15 Zinc and/or Probiotic Supplementation of Rotavirus and Oral Polio Virus Vaccines Completed NCT01616693 Phase 4
16 Sequential Inactivated Poliomyelitis Vaccine Followed by Oral Poliomyelitis Vaccine Versus Oral Poliomyelitis Vaccine Completed NCT01475539 Phase 4
17 A Safety Study of IMOVAX Polio Vaccine in Selected Cities in China Completed NCT01278433 Phase 4
18 A Study of the Safety of IMOVAX Polio™ in China Completed NCT01244464 Phase 4
19 Study to Evaluate the Safety of Co-administration of GSK Biologicals' Poliorix and Infanrix in Healthy Children in Russia Completed NCT01094171 Phase 4
20 Antibody Persistence to REVAXIS or DT Polio and Immune Response to TETRAVAC-ACELLULAIRE Completed NCT01546909 Phase 4
21 Comparison of Immunogenicity and Reactogenicity of INFANRIX™ HEXA and HEXAVAC™ Vaccines as a Primary Vaccination Course Completed NCT01457547 Phase 4
22 Regulatory Post-Marketing Surveillance Study for TETRAXIM™ Completed NCT01437423 Phase 4
23 Study to Evaluate Antibody Persistence in Children Previously Vaccinated With Infanrix Hexa™ or Infanrix-IPV/Hib™ Completed NCT01358825 Phase 4
24 Immunogenicity and Safety of Booster Dose of BoostrixTM Polio Vaccine in Previously Boosted Adults Completed NCT01323959 Phase 4
25 Immunogenicity and Safety of TETRAXIM™ Given as a Booster Dose at 4 to 6 Years of Age Completed NCT01031303 Phase 4
26 Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants Completed NCT00753649 Phase 4
27 Safety and Immunogenicity of a Booster Dose of GSK Biological's Boostrix-Polio Vaccine Completed NCT00635128 Phase 4
28 Study of a New Formulation of DTPa-HBV-IPV/Hib Vaccine Administered as a Booster Dose to 18-23 Months Old Children Completed NCT00611559 Phase 4
29 Immunogenicity and Safety Study of a Booster Dose (5th) of Diphteria-Tetanus-Pertussis-Polio Vaccine Completed NCT00514059 Phase 4 Boostrix polio
30 Assess the Safety & Reactogenicity of DTPa-IPV/Hib Vaccine Administered at 3, 4, 5 & 18 Mths of Age, in Healthy Infants Completed NCT00325156 Phase 4
31 Post-marketing Evaluation of Reactions Following Receipt of Recommended Adolescent Pertussis Vaccine Completed NCT00304265 Phase 4
32 Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand Completed NCT00255021 Phase 4
33 Comparison of Immunity Following IPV Versus fIPV: a Community Based Randomized Controlled Trial in Pakistan Recruiting NCT03286803 Phase 4
34 Evaluation of Immunogenicity and Safety of a Booster Dose of Infanrix Hexa™ in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Recruiting NCT02853929 Phase 4
35 Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Recruiting NCT02422264 Phase 4 Prevnar13
36 Fractional Inactivated Poliovirus Vaccine Booster and Rotavirus Study Active, not recruiting NCT02847026 Phase 4
37 To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan Active, not recruiting NCT01908114 Phase 4
38 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Active, not recruiting NCT03226119 Phase 4
39 Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients Enrolling by invitation NCT02809079 Phase 4 Mycophenolate mofetil;Prednisone
40 Duration of IPV Priming and Antibody Decay Not yet recruiting NCT03202719 Phase 4
41 Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event. Withdrawn NCT00037115 Phase 4 interferon beta 1a;methotrexate;methylprednisolone
42 Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone Unknown status NCT00004645 Phase 3
43 Randomized Clinical Trial to Evaluate Immunogenicity and Safety in Mexicans Newborns Unknown status NCT01870206 Phase 3
44 Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) Unknown status NCT01343355 Phase 2, Phase 3 Tamibarotene
45 Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801 Completed NCT01604746 Phase 3
46 Randomized Controlled Trial for Immunogenicity and Safety Evaluation of Bivalent Types 1 and 3 Oral Poliovirus Vaccine Completed NCT02785705 Phase 3
47 Immunogenicity and Safety of Liquid Bivalent Oral Poliomyelitis Vaccine Completed NCT02434770 Phase 3
48 Immunogenicity of Intramuscular Inactivated Poliovirus Vaccine Completed NCT02291263 Phase 3
49 The Immunogenicity and Safety of Live Attenuated Poliomyelitis Vaccine (Human Diploid Cell) Completed NCT02231632 Phase 2, Phase 3
50 Immunogenicity of Inactivated and Live Polio Vaccines Completed NCT01813604 Phase 3

Search NIH Clinical Center for Myelitis

Cochrane evidence based reviews: myelitis

Genetic Tests for Myelitis

Anatomical Context for Myelitis

MalaCards organs/tissues related to Myelitis:

39
Spinal Cord, Brain, T Cells, Lung, Bone, Bone Marrow, Breast

Publications for Myelitis

Articles related to Myelitis:

(show top 50) (show all 973)
id Title Authors Year
1
Acute transverse myelitis in a pediatric patient. ( 28215959 )
2017
2
Notes from the Field: Cluster of Acute Flaccid Myelitis in Five Pediatric Patients - Maricopa County, Arizona, 2016. ( 28727681 )
2017
3
Hyponatremia associated with human herpesvirus-6 (HHV-6) encephalitis after allogeneic hematopoietic stem cell transplantation: A presentation different from HHV-6 myelitis. ( 28501929 )
2017
4
Outcomes of Colorado children with acute flaccid myelitis at 1 year. ( 28615421 )
2017
5
Refractory Longitudinally Extensive Transverse Myelitis Responsive to Cyclophosphamide. ( 28724464 )
2017
6
Recall radiation myelitis after stereotactic radiation and dabrafenib in metastatic melanoma. ( 27830981 )
2017
7
Urodynamic profile in acute transverse myelitis patients: Its correlation with neurological outcome. ( 28149080 )
2017
8
Abnormal Fluid-Attenuated Inversion Recovery Signal in the Internal Capsule: A Novel Brain Magnetic Resonance Imaging Finding in a Child With Acute Flaccid Myelitis. ( 28262551 )
2017
9
Unusual increase of cases of myelitis in a pediatric hospital in Argentina. ( 28737865 )
2017
10
Comorbidity of narcolepsy with cataplexy and transverse myelitis: aA common autoimmune background? A case report. ( 28449899 )
2017
11
A child with acute transverse myelitis requiring permanent pacemaker implantation. ( 28551037 )
2017
12
Longitudinally Extensive Transverse Myelitis and Optic Neuropathy Associated with Syphilitic Meningomyelitis and Human Immunodeficiency Virus Infection: A Case Report and Review of the Literature. ( 28768983 )
2017
13
Fulminant Acute Ascending Hemorrhagic Myelitis Treated with Eculizumab. ( 28798719 )
2017
14
Hepatitis B virus induced cytoplasmic antineutrophil cytoplasmic antibody-mediated vasculitis causing subarachnoid hemorrhage, acute transverse myelitis, and nephropathy: a case report. ( 28366165 )
2017
15
Transverse myelitis as an unexpected complication following treatment with dinutuximab in pediatric patients with high-risk neuroblastoma: A case series. ( 28748630 )
2017
16
Acute Flaccid Myelitis Among Children - Washington, September-November 2016. ( 28796760 )
2017
17
Enterovirus D68-Associated Acute Flaccid Myelitis in Immunocompromised Woman, Italy. ( 28930024 )
2017
18
Elsberg syndrome: A rarely recognized cause of cauda equina syndrome and lower thoracic myelitis. ( 28534040 )
2017
19
A multicentre randomiSed controlled TRial of IntraVEnous immunoglobulin compared with standard therapy for the treatment of transverse myelitis in adults and children (STRIVE). ( 28639937 )
2017
20
Acute flaccid myelitis and enterovirus D68: DAcjA vu all over again. ( 28615427 )
2017
21
Acute simultaneous development of brain tumour-like lesion and demyelinating polyneuropathy in a patient with chronic relapsing myelitis. ( 28795610 )
2017
22
Acute paraparesis and sensory loss following intravenous corticosteroid administration in a case of longitudinally extensive transverse myelitis caused by spinal dural arteriovenous fistula: case report and review of literature. ( 28546874 )
2017
23
A Rare Infectious Cause of Transverse Myelitis. ( 28004628 )
2017
24
Case series of two patients with Fibrocartilaginous Embolism mimicking Transverse Myelitis of the Spinal Cord. ( 28246010 )
2017
25
Case Report: Zika Virus Meningoencephalitis and Myelitis and Associated Magnetic Resonance Imaging Findings. ( 28829736 )
2017
26
Coxsackie B3/B4-Related Acute Flaccid Myelitis. ( 28324262 )
2017
27
Clinical outcomes and predictive factors related to good outcomes in plasma exchange in severe attack of NMOSD and long extensive transverse myelitis: Case series and review of the literature. ( 28427710 )
2017
28
Physical and Occupational Therapy for a Teenager with Acute Flaccid Myelitis: A Case Report. ( 28095134 )
2017
29
Short segment myelitis as a first manifestation of neuromyelitis optica spectrum disorders. ( 28067584 )
2017
30
A Case of Atopic Myelitis with Cervical Cavernous Angioma. ( 28757876 )
2017
31
A rare case of acute transverse myelitis associated with Staphylococcusaureus bacteremia and osteomyelitis. ( 28584662 )
2017
32
Enterovirus D68 infection in a cluster of children with acute flaccid myelitis, Buenos Aires, Argentina, 2016. ( 28747261 )
2017
33
Atypical Acute Motor Axonal Neuropathy with Cerebrospinal Pleocytosis Mimicking Myelitis. ( 28176505 )
2017
34
Acute Flaccid Myelitis in German Children in 2016-the Return of Polio? ( 28855045 )
2017
35
Clinical commentary on 'Aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder with recurrent short partial transverse myelitis and favorable prognosis: Two new cases', by Wang et al. ( 28580877 )
2017
36
Acute flaccid myelitis in childhood: a retrospective cohort study. ( 28639345 )
2017
37
Pediatric acute transverse myelitis. ( 28678221 )
2017
38
Response to 'Foix-Alajouanine is another differential diagnosis in longitudinal myelitis thought to be a case of multiple sclerosis or neuromyelitis optica'. ( 28868157 )
2017
39
Acute myelitis resembling human T-lymphotropic virus type 1-associated myelopathy presenting as high-signal-intensity long cord lesions on T2-weighted magnetic resonance images combined with lymphoma-type adult T-cell leukemia/lymphoma. ( 27817856 )
2017
40
Chronic neuropathic pain severity is determined by lesion level in aquaporin 4-antibody-positive myelitis. ( 27884934 )
2017
41
Acute flaccid myelitis associated with enterovirus-D68 infection in an otherwise healthy child. ( 28081720 )
2017
42
Cytomegalovirus-related transverse myelitis in an immunocompetent host: a subacute onset of an immune-mediated disease? ( 28801328 )
2017
43
Aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder with recurrent short partial transverse myelitis and favorable prognosis: Two new cases. ( 28580873 )
2017
44
Subacute Progressive Myelopathy: Transverse Myelitis or Subacute Combined Degeneration? A Case Report. ( 28797832 )
2017
45
Thyroid hormone level is associated with the frequency and severity of acute transverse myelitis. ( 28240719 )
2017
46
Chiari I malformation in children with transverse myelitis. ( 28537458 )
2017
47
Postinfectious Anti-Myelin Oligodendrocyte Glycoprotein Antibody Positive Optic Neuritis and Myelitis. ( 28820014 )
2017
48
Etiologic spectrum and functional outcome of the acute inflammatory myelitis. ( 28074391 )
2017
49
Effect of Electroacupuncture Rehabilitation in Transverse Myelitis: A Case Report. ( 28889845 )
2017
50
Neurosarcoidosis-induced longitudinal extensive transverse myelitis. ( 28879911 )
2017

Variations for Myelitis

Expression for Myelitis

Search GEO for disease gene expression data for Myelitis.

Pathways for Myelitis

Pathways related to Myelitis according to GeneCards Suite gene sharing:

(show all 29)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.11 CCL11 HLA-DPB1 IL17A IL6 IL9 MMP2
2
Show member pathways
12.54 CCL11 HLA-DPB1 IL17A IL6 IL9 TNF
3
Show member pathways
12.43 HLA-DPB1 IL17A IL6 TNF
4
Show member pathways
12.41 IL17A IL6 MMP2 TNF
5
Show member pathways
12.25 IL17A IL6 IL9 TNF
6
Show member pathways
12.14 CCL11 IL17A IL6 TNF
7 12.06 HLA-DPB1 IL6 TNF
8
Show member pathways
12.02 CCL11 IL6 TNF
9 12.02 IL6 MMP2 TNF
10 12.01 AQP4 IL6 TNF
11
Show member pathways
11.94 IL17A IL6 IL9 TNF
12
Show member pathways
11.79 IL17A IL6 TNF
13 11.78 AQP4 IL6 MBP TNF
14 11.74 IL6 MMP2 TNF
15 11.72 HLA-DPB1 IL6 TNF
16 11.63 IL17A IL9 TNF
17 11.62 HLA-DPB1 IL17A IL6 TNF
18
Show member pathways
11.5 IL6 MMP2 TNF
19 11.41 CCL11 IL17A IL6 MMP2 TNF
20 11.38 IL6 MMP2 TNF
21 11.36 CCL11 IL6 MMP2 TNF
22 11.33 IL6 MMP2 TNF
23 11.13 IL6 TNF
24 11.11 IL6 TNF
25 10.95 IL6 TNF
26 10.88 IL6 TNF
27 10.78 CCL11 IL17A IL6 IL9 TNF
28 10.77 IL6 IL9
29 10.43 IL17A IL6 IL9 TNF

GO Terms for Myelitis

Cellular components related to Myelitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 APOH CCL11 IL17A IL6 IL9 MMP2
2 external side of plasma membrane GO:0009897 9.26 AQP4 IL17A IL6 TNF
3 extracellular space GO:0005615 9.17 APOH CCL11 IL17A IL6 IL9 MMP2

Biological processes related to Myelitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.65 CCL11 IL6 TNF
2 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.46 MMP2 TNF
3 positive regulation of interleukin-6 secretion GO:2000778 9.43 IL17A MBP
4 cellular response to interleukin-1 GO:0071347 9.43 CCL11 IL17A IL6
5 positive regulation of osteoclast differentiation GO:0045672 9.4 IL17A TNF
6 positive regulation of chemokine production GO:0032722 9.37 IL6 TNF
7 inflammatory response GO:0006954 9.35 CCL11 IL17A IL6 IL9 TNF
8 negative regulation of lipid storage GO:0010888 9.32 IL6 TNF
9 immune response GO:0006955 9.17 CCL11 HLA-DPB1 IL17A IL6 IL9 MBP
10 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.16 IL6 TNF

Molecular functions related to Myelitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 CCL11 IL17A IL6 IL9 TNF

Sources for Myelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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