MCID: MYL001
MIFTS: 52

Myelitis

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Myelitis

MalaCards integrated aliases for Myelitis:

Name: Myelitis 12 72 49 51 41 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:322
MeSH 41 D009187
NCIt 46 C26832
UMLS 69 C0026975

Summaries for Myelitis

Disease Ontology : 12 A spinal cord disease that is characterized by inflammation of the white matter or gray matter of the spinal cord.

MalaCards based summary : Myelitis is related to acute transverse myelitis and transverse myelitis. An important gene associated with Myelitis is AQP4 (Aquaporin 4), and among its related pathways/superpathways are PAK Pathway and Cytokine Signaling in Immune system. The drugs Mitoxantrone and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and t cells, and related phenotypes are hematopoietic system and immune system

Wikipedia : 72 Myelitis is inflammation of the spinal cord which can disrupt the normal responses from the brain to the... more...

Related Diseases for Myelitis

Diseases related to Myelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 338)
# Related Disease Score Top Affiliating Genes
1 acute transverse myelitis 33.4 AQP4 IL6 MMP2
2 transverse myelitis 31.4 APOH AQP4 IL17A IL6 MBP MMP2
3 systemic lupus erythematosus 31.0 APOH HLA-DPB1 IL17A IL6 TNF
4 neuromyelitis optica 30.6 AQP4 HLA-DPB1 IL17A IL6 MBP MOG
5 acute disseminated encephalomyelitis 30.5 AQP4 MBP MOG
6 spinal cord disease 30.5 AQP4 MBP MOG TNF
7 pneumonia 30.4 CCL11 IL6 TNF
8 arteriovenous fistula 30.2 APOH IL6
9 lyme disease 29.7 IL17A IL6 TNF
10 laryngitis 29.7 IL6 TNF
11 spinal cord injury 29.7 AQP4 IL6 TNF
12 rubella 29.7 HLA-DPB1 MOG TNF
13 colitis 29.5 IL17A IL6 TNF
14 spondylitis 29.4 IL17A IL6 TNF
15 intracranial hypertension 29.4 APOH AQP4 TNF
16 wegener granulomatosis 29.4 HLA-DPB1 IL6 TNF
17 optic neuritis 29.3 AQP4 MBP MOG TNF
18 neuritis 29.3 AQP4 MBP MOG TNF
19 dermatitis, atopic 29.3 CCL11 IL17A TNF
20 connective tissue disease 29.3 APOH HLA-DPB1 IL6 TNF
21 reactive arthritis 29.2 IL17A IL6 TNF
22 myocarditis 29.2 IL17A IL6 TNF
23 sialadenitis 29.2 MMP2 TNF
24 rheumatoid arthritis 29.1 HLA-DPB1 IL17A IL6 TNF
25 viral encephalitis 28.9 IL6 MBP TNF
26 internuclear ophthalmoplegia 28.9 AQP4 MBP MOG
27 narcolepsy 28.8 AQP4 HLA-DPB1 MOG TNF
28 multiple sclerosis 28.5 AQP4 IL17A IL6 MBP MOG TNF
29 malaria 28.5 CCL11 IL17A IL6 IL9 TNF
30 demyelinating disease 28.2 AQP4 IL17A MBP MOG TNF
31 acute flaccid myelitis 12.3
32 idiopathic acute transverse myelitis 12.1
33 secondary acute transverse myelitis 12.0
34 radiation myelitis 12.0
35 foix-alajouanine syndrome 11.5
36 antiphospholipid syndrome 11.2
37 thyrotoxic periodic paralysis 10.9
38 lupus - neurological sequelae 10.9
39 paresthesia 10.9
40 encephalitis 10.7
41 papillary conjunctivitis 10.4 CCL11 IL6
42 stiff-person syndrome 10.4
43 chronic eosinophilic pneumonia 10.4 CCL11 IL6
44 meningoencephalitis 10.4
45 scorpion envenomation 10.4 IL6 TNF
46 lupus erythematosus 10.4
47 angioimmunoblastic lymphadenopathy with dysproteinemia 10.4 IL6 TNF
48 critical limb ischemia 10.4 IL6 TNF
49 streptococcal toxic-shock syndrome 10.4 IL6 TNF
50 null-cell leukemia 10.4 IL6 TNF

Graphical network of the top 20 diseases related to Myelitis:



Diseases related to Myelitis

Symptoms & Phenotypes for Myelitis

MGI Mouse Phenotypes related to Myelitis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.91 IL17A IL6 IL9 MBP MMP2 MOG
2 immune system MP:0005387 9.81 CCL11 IL17A IL6 IL9 MBP MMP2
3 respiratory system MP:0005388 9.43 CCL11 IL17A IL6 MMP2 TNF AQP4
4 vision/eye MP:0005391 9.1 IL6 MBP MMP2 MOG TNF AQP4

Drugs & Therapeutics for Myelitis

Drugs for Myelitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 158)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Mitoxantrone Approved, Investigational Phase 4 65271-80-9 4212
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 50-24-8 5755
4
Interferon beta-1a Approved, Investigational Phase 4,Phase 2 145258-61-3 6438354
5
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
6
Phenol Approved, Experimental Phase 4 108-95-2 996
7
Zinc Approved, Investigational Phase 4 7440-66-6 32051 23994
8 Zinc sulfate Approved, Investigational Phase 4 7733-02-0
9
Edetic Acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 60-00-4, 62-33-9 6049
10
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
11
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
12
Mycophenolic acid Approved Phase 4 24280-93-1 446541
13
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
14 Antibodies Phase 4,Phase 3,Phase 2,Phase 1
15 Antibodies, Blocking Phase 4
16 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1
17 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
18 Analgesics Phase 4
19 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1
20 Topoisomerase Inhibitors Phase 4
21 Antiemetics Phase 4,Phase 3,Phase 1
22 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1
23 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 1
24 Autonomic Agents Phase 4,Phase 3,Phase 1
25 Gastrointestinal Agents Phase 4,Phase 3,Phase 1,Phase 2
26 glucocorticoids Phase 4,Phase 3,Phase 1
27 Hormone Antagonists Phase 4,Phase 3,Phase 1
28 Hormones Phase 4,Phase 3,Phase 1
29 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 1
30 Methylprednisolone acetate Phase 4,Phase 3,Phase 1,Phase 2
31 Methylprednisolone Hemisuccinate Phase 4,Phase 3,Phase 1,Phase 2
32 Neuroprotective Agents Phase 4,Phase 3,Phase 1
33 Prednisolone acetate Phase 4,Phase 3,Phase 1,Phase 2
34 Prednisolone hemisuccinate Phase 4,Phase 3,Phase 1,Phase 2
35 Prednisolone phosphate Phase 4,Phase 3,Phase 1,Phase 2
36 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Adjuvants, Immunologic Phase 4,Phase 1,Phase 2
38 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Early Phase 1
39 Antiviral Agents Phase 4,Phase 2,Phase 3,Early Phase 1
40 Interferon-beta Phase 4,Phase 2
41 interferons Phase 4,Phase 2
42 Anti-Bacterial Agents Phase 4
43 Polymyxin B Phase 4
44 Polymyxins Phase 4
45 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
46 Micronutrients Phase 4
47 Trace Elements Phase 4
48 Anticoagulants Phase 4,Phase 3,Phase 2
49 Antidotes Phase 4,Phase 3,Phase 2
50 Calcium, Dietary Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 235)

# Name Status NCT ID Phase Drugs
1 Immunogenicity of 1 or 2 Doses of bOPV in Chilean Infants Primed With IPV Vaccine Unknown status NCT01841671 Phase 4
2 Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders Unknown status NCT02021825 Phase 4 Mitoxantrone
3 Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis Completed NCT00179478 Phase 4 interferon beta 1a 30 ug IM once weekly
4 A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease) Completed NCT00304291 Phase 4 Mitoxantrone
5 Oral Corticotherapy in Megadoses to Treat Multiple Sclerosis During Relapse Completed NCT00753792 Phase 4 methylprednisolone;methylprednisolone;Placebo
6 Immunogenicity of Monovalent Type 2 Oral Poliovirus Vaccine Completed NCT02643368 Phase 4
7 A Study to Evaluate the Safety and Immunogenicity of Monovalent OPV2 in Children Aged 1 to 5 Years in Lithuania Completed NCT02582255 Phase 4
8 A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age Completed NCT02580201 Phase 4
9 Intestinal and Humoral Immunity of Sequential Polio Vaccination Schedules Completed NCT02412514 Phase 4
10 Polio End-game Strategies - Poliovirus Type 2 Challenge Study Completed NCT02189811 Phase 4
11 Study of IMOVAX POLIO® Subcutaneous as a Booster Vaccine in Pre-school Age Children in Japan Completed NCT02005536 Phase 4
12 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4 IPV IM Needle;IPV ID Needle;IPV IM Device;IPV ID Device
13 Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine Completed NCT01831050 Phase 4
14 IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi. Completed NCT01695798 Phase 4
15 Zinc and/or Probiotic Supplementation of Rotavirus and Oral Polio Virus Vaccines Completed NCT01616693 Phase 4
16 Sequential Inactivated Poliomyelitis Vaccine Followed by Oral Poliomyelitis Vaccine Versus Oral Poliomyelitis Vaccine Completed NCT01475539 Phase 4
17 A Safety Study of IMOVAX Polio Vaccine in Selected Cities in China Completed NCT01278433 Phase 4
18 A Study of the Safety of IMOVAX Polio™ in China Completed NCT01244464 Phase 4
19 Study to Evaluate the Safety of Co-administration of GSK Biologicals' Poliorix and Infanrix in Healthy Children in Russia Completed NCT01094171 Phase 4
20 Antibody Persistence to REVAXIS or DT Polio and Immune Response to TETRAVAC-ACELLULAIRE Completed NCT01546909 Phase 4
21 Comparison of Immunogenicity and Reactogenicity of INFANRIX™ HEXA and HEXAVAC™ Vaccines as a Primary Vaccination Course Completed NCT01457547 Phase 4
22 Regulatory Post-Marketing Surveillance Study for TETRAXIM™ Completed NCT01437423 Phase 4
23 Study to Evaluate Antibody Persistence in Children Previously Vaccinated With Infanrix Hexa™ or Infanrix-IPV/Hib™ Completed NCT01358825 Phase 4
24 Immunogenicity and Safety of Booster Dose of BoostrixTM Polio Vaccine in Previously Boosted Adults Completed NCT01323959 Phase 4
25 Immunogenicity and Safety of TETRAXIM™ Given as a Booster Dose at 4 to 6 Years of Age Completed NCT01031303 Phase 4
26 Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants Completed NCT00753649 Phase 4
27 Safety and Immunogenicity of a Booster Dose of GSK Biological's Boostrix-Polio Vaccine Completed NCT00635128 Phase 4
28 Study of a New Formulation of DTPa-HBV-IPV/Hib Vaccine Administered as a Booster Dose to 18-23 Months Old Children Completed NCT00611559 Phase 4
29 Immunogenicity and Safety Study of a Booster Dose (5th) of Diphteria-Tetanus-Pertussis-Polio Vaccine Completed NCT00514059 Phase 4 Boostrix polio
30 Assess the Safety & Reactogenicity of DTPa-IPV/Hib Vaccine Administered at 3, 4, 5 & 18 Mths of Age, in Healthy Infants Completed NCT00325156 Phase 4
31 Post-marketing Evaluation of Reactions Following Receipt of Recommended Adolescent Pertussis Vaccine Completed NCT00304265 Phase 4
32 Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand Completed NCT00255021 Phase 4
33 Comparison of Immunity Following IPV Versus fIPV: a Community Based Randomized Controlled Trial in Pakistan Recruiting NCT03286803 Phase 4
34 Duration of IPV Priming and Antibody Decay Recruiting NCT03202719 Phase 4
35 Evaluation of Immunogenicity and Safety of a Booster Dose of Infanrix Hexa™ in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Recruiting NCT02853929 Phase 4
36 Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Recruiting NCT02422264 Phase 4 Prevnar13
37 Fractional Inactivated Poliovirus Vaccine Booster and Rotavirus Study Active, not recruiting NCT02847026 Phase 4
38 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Active, not recruiting NCT03226119 Phase 4
39 To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan Active, not recruiting NCT01908114 Phase 4
40 Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients Enrolling by invitation NCT02809079 Phase 4 Mycophenolate mofetil;Prednisone
41 Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event. Withdrawn NCT00037115 Phase 4 interferon beta 1a;methotrexate;methylprednisolone
42 Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone Unknown status NCT00004645 Phase 3
43 Randomized Clinical Trial to Evaluate Immunogenicity and Safety in Mexicans Newborns Unknown status NCT01870206 Phase 3
44 Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) Unknown status NCT01343355 Phase 2, Phase 3 Tamibarotene
45 Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801 Completed NCT01604746 Phase 3
46 Randomized Controlled Trial for Immunogenicity and Safety Evaluation of Bivalent Types 1 and 3 Oral Poliovirus Vaccine Completed NCT02785705 Phase 3
47 Immunogenicity and Safety of Liquid Bivalent Oral Poliomyelitis Vaccine Completed NCT02434770 Phase 3
48 Immunogenicity of Intramuscular Inactivated Poliovirus Vaccine Completed NCT02291263 Phase 3
49 The Immunogenicity and Safety of Live Attenuated Poliomyelitis Vaccine (Human Diploid Cell) Completed NCT02231632 Phase 2, Phase 3
50 Immunogenicity of Inactivated and Live Polio Vaccines Completed NCT01813604 Phase 3

Search NIH Clinical Center for Myelitis

Cochrane evidence based reviews: myelitis

Genetic Tests for Myelitis

Anatomical Context for Myelitis

MalaCards organs/tissues related to Myelitis:

38
Spinal Cord, Brain, T Cells, Lung, Bone, Bone Marrow, B Cells

Publications for Myelitis

Articles related to Myelitis:

(show top 50) (show all 1002)
# Title Authors Year
1
Acute Transverse Myelitis Caused by Echovirus 11 in a Pediatric Patient: Case Report and Review of the Current Literature. ( 29372173 )
2018
2
Evaluation of idiopathic transverse myelitis revealing specific myelopathy diagnoses. ( 29247071 )
2018
3
Reversible paraspinal muscle hyperintensity in anti-MOG antibody-associated transverse myelitis. ( 29114566 )
2018
4
Cytomegalovirus associated longitudinally extensive transverse myelitis and acute hepatitis in an immunocompetent adult. ( 29396069 )
2018
5
MOG-antibody demyelinating diseases: a case of post-partum severe rhombencephalitis and transverse myelitis. ( 29438836 )
2018
6
Necrotic-hemorrhagic myelitis: A rare malignant variant of parainfectious acute disseminated encephalomyelitis in childhood. ( 29249379 )
2018
7
Guillain-BarrAc syndrome, transverse myelitis and infectious diseases. ( 29375121 )
2018
8
Causation of Acute Flaccid Paralysis by Myelitis and Myositis in Enterovirus-D68 Infected Mice Deficient in Interferon I+I^/I^ Receptor Deficient Mice. ( 29329211 )
2018
9
MRI Features of Aquaporin-4 Antibody-Positive Longitudinally Extensive Transverse Myelitis: Insights into the Diagnosis of Neuromyelitis Optica Spectrum Disorders. ( 29449281 )
2018
10
Clinical features and prognoses of acute transverse myelitis in patients with systemic lupus erythematosus. ( 29294596 )
2018
11
Acute transverse myelitis following scrub typhus: A case report and review of the literature. ( 29350608 )
2018
12
The association between acute flaccid myelitis (AFM) and Enterovirus D68 (EV-D68) - what is the evidence for causation? ( 29386095 )
2018
13
CLIPPERS with longitudinally extensive transverse myelitis: Role of T versus B cells. ( 29406923 )
2018
14
Clinical Features of Acute Flaccid Myelitis Temporally Associated With an Enterovirus D68 Outbreak: Results of a Nationwide Survey of Acute Flaccid Paralysis in Japan, August-December 2015. ( 29028962 )
2018
15
Acute myelitis associated with human herpesvirus 7 infection. ( 29359421 )
2018
16
Occult Disseminated Tuberculosis with Holocord Longitudinally Extensive Transverse Myelitis: A Rare Phenomenon in a Child. ( 29204202 )
2017
17
Acute myelitis resembling human T-lymphotropic virus type 1-associated myelopathy presenting as high-signal-intensity long cord lesions on T2-weighted magnetic resonance images combined with lymphoma-type adult T-cell leukemia/lymphoma. ( 27817856 )
2017
18
Elsberg syndrome: A rarely recognized cause of cauda equina syndrome and lower thoracic myelitis. ( 28534040 )
2017
19
Spinal Cord Infarction Mimicking Acute Transverse Myelitis. ( 29441246 )
2017
20
A Rare Infectious Cause of Transverse Myelitis. ( 28004628 )
2017
21
Comment on 'Acute flaccid myelitis in childhood: a retrospective cohort study'. ( 29024358 )
2017
22
Acute Flaccid Myelitis: Etiologic Challenges, Diagnostic and Management Considerations. ( 29181601 )
2017
23
Postinfectious Anti-Myelin Oligodendrocyte Glycoprotein Antibody Positive Optic Neuritis and Myelitis. ( 28820014 )
2017
24
Fulminant Acute Ascending Hemorrhagic Myelitis Treated with Eculizumab. ( 28798719 )
2017
25
Acute flaccid myelitis associated with enterovirus-D68 infection in an otherwise healthy child. ( 28081720 )
2017
26
A Case of Atopic Myelitis with Cervical Cavernous Angioma. ( 28757876 )
2017
27
Urodynamic profile in acute transverse myelitis patients: Its correlation with neurological outcome. ( 28149080 )
2017
28
Chiari I malformation in children with transverse myelitis. ( 28537458 )
2017
29
Outcomes of Colorado children with acute flaccid myelitis at 1 year. ( 28615421 )
2017
30
Acute flaccid myelitis and enterovirus D68: DAcjA vu all over again. ( 28615427 )
2017
31
Abnormal Fluid-Attenuated Inversion Recovery Signal in the Internal Capsule: A Novel Brain Magnetic Resonance Imaging Finding in a Child With Acute Flaccid Myelitis. ( 28262551 )
2017
32
Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient. ( 28785494 )
2017
33
Aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder with recurrent short partial transverse myelitis and favorable prognosis: Two new cases. ( 28580873 )
2017
34
Subacute Progressive Myelopathy: Transverse Myelitis or Subacute Combined Degeneration? A Case Report. ( 28797832 )
2017
35
Clinical outcomes and predictive factors related to good outcomes in plasma exchange in severe attack of NMOSD and long extensive transverse myelitis: Case series and review of the literature. ( 28427710 )
2017
36
Longitudinally extensive transverse myelitis after<i>Campylobacter jejuni</i>enteritis. ( 29273615 )
2017
37
Acute Flaccid Myelitis in German Children in 2016-the Return of Polio? ( 28855045 )
2017
38
Leber Hereditary Optic Neuropathy and Longitudinally Extensive Transverse Myelitis. ( 29249004 )
2017
39
Acute Flaccid Myelitis Among Children - Washington, September-November 2016. ( 28796760 )
2017
40
Coxsackie B3/B4-Related Acute Flaccid Myelitis. ( 28324262 )
2017
41
Enterovirus D68 infection in a cluster of children with acute flaccid myelitis, Buenos Aires, Argentina, 2016. ( 28747261 )
2017
42
Transverse myelitis following methotrexate treatment of ectopic pregnancy: a case report. ( 29260596 )
2017
43
Acute transverse myelitis in a pediatric patient. ( 28215959 )
2017
44
Etiologic spectrum and functional outcome of the acute inflammatory myelitis. ( 28074391 )
2017
45
Physical and Occupational Therapy for a Teenager with Acute Flaccid Myelitis: A Case Report. ( 28095134 )
2017
46
Clinical commentary on 'Aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder with recurrent short partial transverse myelitis and favorable prognosis: Two new cases', by Wang et al. ( 28580877 )
2017
47
Ventriculoperitoneal Shunt-Associated Vancomycin-Resistant Meningitis Complicating a Patient Undergoing Plasmapheresis for Presumed Systemic Lupus Erythematosus-Associated Transverse Myelitis. ( 29109928 )
2017
48
Acute motor axonal neuropathy and transverse myelitis overlap: the importance of history taking. ( 29143293 )
2017
49
Unusual increase of cases of myelitis in a pediatric hospital in Argentina. ( 28737865 )
2017
50
Successfully Managed Acute Transverse Myelitis Related to Scrub Typhus and Serial Image Findings. ( 28115665 )
2017

Variations for Myelitis

Expression for Myelitis

Search GEO for disease gene expression data for Myelitis.

Pathways for Myelitis

Pathways related to Myelitis according to GeneCards Suite gene sharing:

(show all 31)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.11 CCL11 IL17A IL6 IL9 TNF
2
Show member pathways
13.11 CCL11 HLA-DPB1 IL17A IL6 IL9 MMP2
3
Show member pathways
12.54 CCL11 HLA-DPB1 IL17A IL6 IL9 TNF
4
Show member pathways
12.44 HLA-DPB1 IL17A IL6 TNF
5
Show member pathways
12.42 IL17A IL6 MMP2 TNF
6
Show member pathways
12.26 IL17A IL6 IL9 TNF
7
Show member pathways
12.14 CCL11 IL17A IL6 TNF
8 12.07 HLA-DPB1 IL6 TNF
9
Show member pathways
12.03 CCL11 IL6 TNF
10 12.02 IL6 MMP2 TNF
11 12.01 AQP4 IL6 TNF
12
Show member pathways
11.94 IL17A IL6 IL9 TNF
13
Show member pathways
11.78 IL17A IL6 TNF
14 11.78 AQP4 IL6 MBP TNF
15 11.75 IL6 MMP2 TNF
16 11.73 HLA-DPB1 IL6 TNF
17 11.64 IL17A IL9 TNF
18 11.62 HLA-DPB1 IL17A IL6 TNF
19
Show member pathways
11.51 IL6 MMP2 TNF
20 11.41 CCL11 IL17A IL6 MMP2 TNF
21 11.38 IL6 MMP2 TNF
22 11.36 CCL11 IL6 MMP2 TNF
23 11.33 IL6 MMP2 TNF
24 11.14 IL6 TNF
25 11.12 IL6 TNF
26 10.96 IL6 TNF
27 10.89 IL6 TNF
28 10.83 CCL11 IL17A IL6 IL9 TNF
29 10.78 CCL11 IL17A IL6 IL9 TNF
30 10.68 IL6 IL9
31 10.43 IL17A IL6 IL9 TNF

GO Terms for Myelitis

Cellular components related to Myelitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 APOH CCL11 IL17A IL6 IL9 MMP2
2 extracellular space GO:0005615 9.17 APOH CCL11 IL17A IL6 IL9 MMP2

Biological processes related to Myelitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of receptor activity GO:0010469 9.55 CCL11 IL17A IL6 IL9 TNF
2 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.43 MMP2 TNF
3 positive regulation of interleukin-6 secretion GO:2000778 9.4 IL17A MBP
4 positive regulation of osteoclast differentiation GO:0045672 9.37 IL17A TNF
5 inflammatory response GO:0006954 9.35 CCL11 IL17A IL6 IL9 TNF
6 positive regulation of chemokine production GO:0032722 9.32 IL6 TNF
7 negative regulation of lipid storage GO:0010888 9.26 IL6 TNF
8 immune response GO:0006955 9.17 CCL11 HLA-DPB1 IL17A IL6 IL9 MBP

Molecular functions related to Myelitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 CCL11 IL17A IL6 IL9 TNF

Sources for Myelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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