MCID: MYL020
MIFTS: 44

Myelomeningocele malady

Rare diseases, Neuronal diseases, Fetal diseases categories

Aliases & Classifications for Myelomeningocele

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 47Novoseek, 12DISEASES, 51Orphanet, 2CDC, 36MeSH, 28ICD10 via Orphanet
See all sources

Summaries for Myelomeningocele

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NIH Rare Diseases:45 Myelomeningocele is the most severe form of spina bifida. it happens when parts of the spinal cord and nerves come through the open part of the spine. it causes nerve damage and other disabilities. seventy to ninety percent of children with this condition also have too much fluid on their brains (hydrocephalus). this happens because fluid that protects the brain and spinal cord is unable to drain like it should. the fluid builds up, causing pressure and swelling. without treatment, a person’s head grows too big, and they may have brain damage. other disorders of the spinal cord may be seen, including syringomyelia and hip dislocation. the cause of myelomeningocele is unknown. however, low levels of folic acid in a woman's body before and during early pregnancy is thought to play a part in this type of birth defect. last updated: 1/11/2013

MalaCards based summary: Myelomeningocele, also known as meningomyelocele, is related to neural tube defects, folate-sensitive and occipital encephalocele. An important gene associated with Myelomeningocele is MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H)), and among its related pathways are Folate-Alcohol and Cancer Pathway and Folate Metabolism. Affiliated tissues include spinal cord, brain and skin, and related mouse phenotypes are craniofacial and other.

Disease Ontology:10 A spina bifida characterized by protrusion of the spinal cord through an opening, covered by meningeal membranes.

CDC:2 Spina bifida is a major birth defect of a person’s spine. With good quality medical care people with spina bifida can reach their full potential. If you have spina bifida, or know someone who does, it’s important to get the facts so that you can make the best possible health care choices.

Related Diseases for Myelomeningocele

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Diseases related to Myelomeningocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 155)
idRelated DiseaseScoreTop Affiliating Genes
1neural tube defects, folate-sensitive30.0MTHFD1, MTHFR, MTRR
2occipital encephalocele29.5MTHFD1, MTHFR, T, VANGL1, VANGL2
3neural tube defects28.3CBS, CELSR1, DACT1, MTHFD1, MTHFR, MTRR
4hydrocephalus10.6
5neurogenic bladder10.5
6chiari malformation10.5
7cervicitis10.4
8scoliosis10.4
9tethered spinal cord syndrome10.3
10spina bifida aperta10.3
11imperforate anus10.3
12renal agenesis meningomyelocele mullerian defect10.3
13neurogenic bowel10.3
14cerebritis10.3
15congenital nervous system abnormality10.3
16myelocystocele10.3
17constipation10.2
18chiari malformation type 210.2
19split cord malformation10.2
20sacrococcygeal teratoma10.2
21obesity10.2
22focal dermal hypoplasia10.2
23spinal cord injury10.2
24meningocele10.2
25clubfoot10.2
26syringomyelia10.2
27strabismus10.2
28encephalocele10.2
29syringohydromyelia10.2
30familial benign flecked retina10.2MTHFR, VANGL2
31angioimmunoblastic lymphadenopathy with dysproteinemia10.2MTHFR, VANGL1
32omphalocele10.1
33spina bifida occulta10.1
34glycine n-methyltransferase deficiency10.1CBS, MTHFR
35fraser syndrome10.1
36diaphanospondylodysostosis10.1
37caudal duplication anomaly10.1
38cerebrocostomandibular syndrome10.1
39otopalatodigital syndrome, type ii10.1
40child syndrome10.1
41anencephaly10.1
42cerebral palsy10.1
43urethritis10.1
44choroiditis10.1
45waardenburg's syndrome10.1
46neuromuscular disease10.1
47sleep disorder10.1
48spinal cord disease10.1
49chromosome 8q duplication10.1
50growth hormone deficiency10.1

Graphical network of the top 20 diseases related to Myelomeningocele:



Diseases related to myelomeningocele

Symptoms for Myelomeningocele

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Drugs & Therapeutics for Myelomeningocele

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Drugs for Myelomeningocele (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Oxybutyninapproved, investigationalPhase 4625633-20-54634
Synonyms:
1508-65-2 (hydrochloride)
4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
4-(diethylamino)-2-butynyl-alpha-cyclohexyl-alpha-hydroxybenzeneacetate
4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate
4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
4-(diethylamino)but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate
4-Diethylamino-2-butinyl alpha-cyclohexylmandelat
4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
5633-20-5
AC-2153
AC1L1ILV
BPBio1_000214
BRD-A65013509-003-03-8
BSPBio_000194
Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester
C07360
CCRIS 1923
CHEBI:7856
CHEMBL1231
CID4634
Cyclohexaneglycolic acid, .alpha.-phenyl-, 4-(diethylamino)-2-butynyl ester
Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester
Cystrin
D00465
DB01062
Ditropan
Ditropan, Lyrinel XL, Oxytrol, Oxybutynin
FT-0082890
Gelnique
HSDB 3270
I06-2117
L000923
LS-28714
 
Lopac0_000923
MolPort-003-849-741
NCGC00015767-06
NCGC00089795-02
Oxibutinina
Oxibutinina [INN-Spanish]
Oxibutyninum
Oxybutinin
Oxybutynin
Oxybutynin (USAN/INN)
Oxybutynin Base
Oxybutynin Chloride
Oxybutynin Hydrochloride
Oxybutynin [USAN:INN:BAN]
Oxybutynin topical gel
Oxybutynine
Oxybutynine [INN-French]
Oxybutyninum
Oxybutyninum [INN-Latin]
Oxytrol
Oxytrol (TN)
Oxytrol For Women
Pollakisu
Prestwick0_000287
Prestwick1_000287
Prestwick2_000287
Prestwick3_000287
S1754_Selleck
SPBio_002413
Transdermal patch
UNII-K9P6MC7092
oxybutynin
oxybutynin topical gel
transdermal patch
2Botulinum ToxinsPhase 4590
3Botulinum Toxins, Type APhase 4561
4
Darifenacinapproved, investigationalPhase 222133099-04-4444031
Synonyms:
(S)-1-(2-(2,3-Dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide
(S)-1-(2-(2,3-dihydro-5-Benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide
133099-04-4
2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide
2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide
AC-302
AC1L9FKY
CHEBI:391960
CHEMBL1346
CID444031
D03654
DB00496
 
Darifenacin
Darifenacin (USAN/INN)
Darifenacin Hydrobromide
Darifenacina
Darifenacinum
Darifénacine
Emselex
Enablex
LS-187359
MolPort-005-943-011
NCGC00168775-01
STOCK6S-73577
darifenacin
5MethenaminePhase 18
6Methenamine hippuratePhase 18
7AcidophilusNutraceuticalPhase 1444
8
Mentholapproved17482216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
999 Itch Relief
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
Absorbine Back Therapeutic Pain Relief
Absorbine Jr
Absorbine Jr Ultra Strength Pain Relieving
Absorbine Jr.
Absorbine Jr. Back
Algomend Pain Relief
Alhua Huogan Pain Relieving Patch
Aloemint Skin Aid
Amar Ice
Analgesic
Anc Neverpain External Analgesic
Anti Itch
Army Health Pain Reliever
Arthri-support
Arthri-zen Relief
Arthripain Relief
Arthritis Relief
Aspercreme Heat
Aspercreme Max No Mess Roll On
Assured Cold N Hot Pain Relief Menthol
Assured Extra Strength Cold N Hot
Assured Ice Cold Topical Analgesic
Assured Muscle Rub
Assured Pain Relief Hot Menthol
Atopalm Pain Relieving
Aurorae Healing Pain Relieving Roll-on
Avapta
Avedana Pain Relieving Roll On
Avedana Pain-relieving
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
Babyganics Cold Relief Chest Rub
Barox
Barox BODY CARE MASSAGE
Barox Body Care Massage Relax Refresh Revital
Being Well Extra Strength Menthol Heat
Bengay Ultra Strength Large Size
Bengay Ultra Strength Pain Relieving Large Size
Bengay Ultra Strength Pain Relieving Regular Size
Bengay Ultra Strength Regular Size
Bengay Vanishing Scent
Bengay Zero Degrees Menthol Pain Relieving
Bentasil SUGAR FREE BLACKCURRANT SOFT Texture
Bentasil SUGAR FREE CHERRY SOFT Texture
Bentasil SUGAR FREE HONEY LEMON SOFT Texture
Berri-freez
Besthealth Cherry
Besthealth Cough Suppressant Sugar Free Black Cherry Flavor
Besthealth Cough Suppressant Sugar Free Honey Lemon Flavor
Besthealth Honey Lemon
Besthealth Menthol
Bio 2 Brazilian Heat Brazilian Heat
Bio-scriptives Extreme Pr
Bioblast Pain Relief
Bioflexor
Biofreeze
Biofreeze Colorless
Biofreeze Colorless Roll-on
Biofreeze Roll-on
Biorelief Ice Pain Relieving
Blistex Ivarest Medicated Poison Ivy Cleansing Foam
Blue Gel Pain Relieving
Blue Ice
Blue Ice Analgesic
Blue Ice Analgesic Gel
Blue Ice Pain Relieving
Body
Budpack Muscle Rub
Budpak Muscle Rub
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Canker Complete Canker Sore Relief
Caswell No. 540
Celadrin
Cepacol Sore Throat From Post Nasal Drip
Cepacol Sore Throat Regular Strength
Ching Wan Hung Soothing Herbal Balm
Choice Personal Care Theraputic Blue Ice
Cold Hot Patch
Cold Spot Point Relief
Coldaid
Cool N Heat Patch For Back Extra Strength
Coralite Extra Strength Menthol Pain Relief Sleeve - Knee
Coralite Extra Strength Menthol Pain Relief Sleeve - Wrist
Coralite Pain Relief
Counteract Cough Drops Honey Lemon
Counteract Cough Drops Orchard Cherry
Cryogel Island Rain Natural Pain Relieving Vitaminerals
Cvs Cold Hot Medicated
Cvs Soothing Itch Relief
Cvs Sore Muscle Rub Vanishing Scent
Cvs Therapeutic Menthol Gel
Cvs Therapeutic Menthol Pain Reliever
Cvs Tropical Citrus Cough
Cvs Ultra Strength Pain Relieving
Cvs Vanishing Scent Muscle Rub
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
Dg Health Extra Strength Medicated
Dg Health Pain Relieving
Dg Ice Cold Analgesic
Diapedic Foot Treatment
DivK1c_000820
Dorflex Icy Hot Flexible, Large
Dorflex Icy Hot Flexible, Small
Dorflex Icy Hot Flexible, XL
Dr. Blue
Dt Ice Cold Analgesic
Dual Action Cherry Cough Suppressant Oral Anesthetic
Dynafreeze
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
Easy
Eb301ap Pain Relief
Eb301ct Bruise Pain Relief
Eb302 Arthritis Relief
Ecolyptus Pain Relieving Muscle Rub
Efac Pain Relieving
Elgin Pain Relief
Equaline Blue Ice Pain Relieving
Equate Menthol Extra Strength
Eros Iron Man
Eucalyptamint
Eucerin Calming Itch Relief Treatment
Extra Strength Cold N Hot Pain Relief Medicated
Extra Strength Pain Relief Therapy
Extra Strength Stopain Cold Pain Relieving
Extra Strength Stopain Cold Pain Relieving Roll On
FEMA No. 2665
Family Care Maximum Strength Medicated Anti Itch
Fast Freeze
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
Flexall Pain Relieving
Flexgen
Fluaid
Foot Works Achy Foot Massager Pain Relieving
Gold Bond Foot Extra Strength
Gold Bond Medicated Foot
Gold Bond Pain Relieving Foot
Gold Bond Pain Relieving Foot Roll On
Green Bamboo
Green Guard Cough Drop Relief
HMS1922G13
HMS2092L14
HMS502I22
HSDB 5662
HSDB 593
Halls Apple Cider
Halls Butterscotch
Halls Cherry
Halls Extra Strong Menthol
Halls Honey Lemon
Halls Ice Peppermint
Halls MENTHO-LYPTUS
Halls Melon Splash
Halls Menthol
Halls Mentholyptus
Halls Mocha Mint
Halls Naturals Honey Lemon Chamomile
Halls Plus Cherry
Halls Plus Honey
Halls Plus Strawberry
Halls Spearmint
Halls Strawberry
Halls Sugar Free Black Cherry
Halls Sugar Free Citrus Blend
Halls Sugar Free Extra Strong Menthol
Halls Sugar Free Honey Berry
Halls Sugar Free Honey Lemon
Halls Sugar Free Mountain Menthol
Halls Tropical Fruit
Hallsmelon Splash Melon Splash
Hallssugar Free Extra Sugar Free Extra Strong Menthol
Han Honey Loquat Syrup
Hanbang Cataplasma
Harmon Extra Strength Pain Relieving
Harmon Extra Strength Pain Relieving Roll-on
Headache crystals
Health Smart Medicated Foot
Herbion Naturals Honey Lemon
Herbion Naturals Honey Lemon Cough Drops
Herbion Naturals Honey-Lemon Cough Drops
Herbion Naturals Mint Cough Drops
Herbion Naturals Orange
Herbion Naturals Orange Cough Drops
Hexahydrothymol
Hielo Ardiente
Honibe
 
Hot Ice Soothing Analgesic Gel
Huitomi Slimming Sports
Humphreys Bendito Alcoholado
I06-1216
I14-7371
IDI1_000820
Ice
Ice Cold Analgesic
Ice Cold Topical Analgesic Gel
Ice External Analgesic Leader
Ice Quake
Ice Quake Muscle Rub
Icy Cool Maximum Strength
Icy Hot
Icy Hot Back
Icy Hot Medicated
Icy Hot Medicated No Mess Applicator
Icy Hot Medicated Roll Large
Icy Hot Medicated Roll Medium
Icy Hot Medicated Roll, Large
Icy Hot Medicated Roll, Medium
Icy Hot Medicated, Advanced Relief
Icy Hot Medicated, Back
Icy Hot Medicated, XL
Icy Hot Naturals
Icy Hot Power Gel
Icy Hot Vanishing Scent
Icyhot Medicated
Imada Four Seasons Safe Analgesic Balm
Jakemans Blueberry
Jakemans Cherry
Jakemans Peppermint
K2 Cold Therapy
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
Kay Medic Menthol Pain Relief
Kool Comfort
Kool Comfort Pain Relieving Roll-on
Kpp Triple Action
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
La Jiao Feng Shi Gao
Lander Polar Ice
Leader Cough Drops Cherry Flavor
Leader Cough Drops Honey Lemon
Leader Cough Drops Menthol Flavor
Leader Extra Strength Medicated Pain Relief Patch
Leader Sugar Free Cough Drops Black Cherry
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
Linkus Lozenges Cough Suppressant/Oral Anesthetic
Low Sugar Cherry Flavor Fishermans Friend Menthol Cough Suppressant
Ludens Honey Lemon Throat Drops
Ludens Honey Licorice Throat Drops
Ludens Original Menthol Throat Drops
Lurosil
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Makesense Extra Strength Muscle Rub
Maxfit Freeze Gel
Maybelline New York Baby Lips Dr Rescue Medicated Balm
Medi First Plus Cherry Cough Drops
Medi-first Cherry Cough Drops
Medic Ice
Medicated Body Powder
Medicated Pain Relief
Mediflex
Medique Medikoff Drops
Medique Sugar Free Medikoff Drops
Meditowel PAIN RELIEF
Meijer Cherry Cough Drops
Meijer Honey Lemon Cough Drops
Meijer Menthol Cough Drops
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol Fresh Cough Suppressant
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Mentholatum Pain Relief Extra Strength
Mentholatum Sports Pain Relief Cold
Menthomenthol
Menthyl alcohol
Mineral Ice Pain Relieving
Miracle Foot Repair
Miracle Foot Repair Cream
Miracle Of Aloe Rub Roll On
Miracle Pain Cream
Moisture Therapy Anti-Itch
MolPort-000-849-729
MolPort-001-793-392
Moore Medical Cherry Cough Suppressant/anesthetic Drops
Moore Medical Sugar Free Black Cherry Cough Suppressant/anesthetic Drops
Moore Medical Sugar Free Menthol Cough Suppressant/anesthetic Drops
Mr Dudleys Topical Pain Relief
Muscle
Muscle Rub Ultra Strength Pain Relieving
Myo-breathe
Myorx Low Dose Pain Relieving
Myorx Pain Relieving
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Nan San Easy Flex Pain Relieving
Natural Cherry Honey Herb Throat Drops
Natural Herb cough drop
Natural Honey Herb Cough Suppressant Throat Drops
Natural Lemon Mint Herb Throat Drops
Natural Pain Relieving Lavender Breeze Cryogel
Natures Choice Cool Hot Ice
Natures Sunshine Products Everflex Topical Analgesic Pain Relief
Neoisomenthol
Nice Assorted
Nice Cherry
Nice Citrus
Nice Cool Mint
Nice Honey Lemon
Nice Menthol
No Pain More Gain
North Cough Drop
Numotizine
Olbas Lozenges Maximun Strength
Olbas Pastilles
Original Extra Strong All Natural Fishermans Friend Menthol Cough Suppressant
Ortho-nesic
Osmoflex
Oxyrub Pain Relief
Pain Relief Balmpreferred Plus Ph Preferred Plus Pharmacy
Pain Relief Therapy Patch
Pain Reliever
Pain Relieving
Pain Relieving Analgesic
Pain Relieving Patch
Pain Relieving Patch Ultra Strength
Pain Relieving Patch Ultra Strength ULTRA STRENGTH
Panitrol XR
Paraid Extra Strength Menthol Pain Relief Sleeve Knee Large Ankles Elbows
Patch Scherer Labs
Patch Walgreens
Peppermint camphor
Perfect Purity Hotice
Perfect Purity Medicated Foot Powder
Perform
Personal Care Extra Strength Cold Hot
Personal Care Ice Cold
Plaster MandAHerbalPlaster
Po Sum On Medicated
Polar Frost Cold
Power Relief
Preferred Plus Body Powder
Premier Value Medicated Foot Powder
Q Health Pain Relief Spray
Quickflex
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Raw Heat
Raw Ice
Reactice Reactivating Ice Baume
Red Lion Relief
Relief Pain Relieving Cream
Rexall Vanishing Scent Pain Relieving
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Screamin Menthol Toast
Sella Natural
Skin So Soft Bug Guard Plusitch Relief itch relief
Smith Bros Honey Lemon Cough Drops
Smith Bros Menthol Eucalyptus Cough Drops
Smith Bros Sugar-free Black Cherry Cough Drops
Sof Skin Icy Blue
Sofskin Ice Analgesic
Sombra Cool Therapy
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Stopain Cold Pain Relieving
Stopain Cold Professional Strength Pain Relieving
Stopain Extra Strength Pain Relieving
Sub-zero COOL PAIN RELIEVING
Sugar Free Cherry Fishermans Friend Menthol Cough Suppressant
Sugar Free Cherry Herb Throat Drops
Sugar Free Lemon Mint Herb Throat Drops
Sugar Free Mountain Herb Cough Suppressant Throat Drops
Sugar Free Original Swiss Herb Cough Suppressant Throat Drops
Sugar Free Refreshing Mint Fishermans Friend Menthol Cough Suppressant
Sugar Free Swiss Cherry Herb Throat Drops
The Medicine Shoppe Extra Strength Pain Relieving
The Original Natural Herb Cough Drops
Therafreeze
Theraid
Therapeutic Relief Preferred Plus Pharmacy
Theraplus Plus
Throat Coat
Tianhe Guben Yaoshen Tie Gao
Top Care Medicated
Topcare Medicated
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
Ultra Strength Stopain Pain Relieving
Us Favorite Cold Pain Relieving
Vaporizing Colds Rub
Vicks Vapodrops Cough Relief
Vitaminerals Inc. Cryogel Natural Pain Relieving
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
Walgreens Aloe Vera Cooling
Watermelon Frost Sore Throat
Wellpatch Backache Pain Relief
Xtracare Ice Cold Topical Analgesic Gel
Youngevity Invision CM
Yun Xiang Jing
ZINC01482164
Zhong Hua Jiu Patch
Zims Arnica Max
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
9ColaNutraceutical1690

Interventional clinical trials:

(show all 18)
idNameStatusNCT IDPhase
1Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord LesionsCompletedNCT01208584Phase 4
2Effect of Botulinum Toxin in Neurogenic Bladders in Children With MyelomeningoceleActive, not recruitingNCT00175123Phase 4
32 Week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Yrs) With Neurogenic Detrusor OveractivitySuspendedNCT00712322Phase 2
4Fetoscopic Meningomyelocele Repair StudyRecruitingNCT02230072Phase 1
5Bacteriuria Eradication Through ProbioticsEnrolling by invitationNCT00717600Phase 1
6Management of Myelomeningocele Study (MOMS)CompletedNCT00060606
7Feasibility of the Portable YouGrabber SystemCompletedNCT02368223
8Prenatal Surgical Repair of Fetal MyelomeningoceleRecruitingNCT01983345
9Extended Criteria For Fetal Myelomeningocele RepairRecruitingNCT02664207
10Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0RecruitingNCT02509377
11Evaluation of Hysterotomy Site After Open Fetal SurgeryRecruitingNCT02493062
12Reliability of the Melbourne AssessmentRecruitingNCT02595411
13Reciprocating Gait Orthoses for Paraplegia PatientsRecruitingNCT02227407
14Extramembranous and Interosseous Technique of Tibialis Posterior Tendon TransferRecruitingNCT01751503
15Retrograde Colonic Irrigation to Manage Spina Bifida Functional Digestive Sequelae: a Multicenter, Prospective, Randomized Controlled TrialRecruitingNCT02361450
16Self-esteem and Neuro-urological Follow-up in Patients With Spina Bifida or Spinal Cord InjuryRecruitingNCT01606618
17Psychosocial Adjustment of Adolescents With Spina BifidaActive, not recruitingNCT00891891
18Prenatal Endoscopic Repair of Fetal Spina BifidaNot yet recruitingNCT02390895

Search NIH Clinical Center for Myelomeningocele


Cochrane evidence based reviews: Meningomyelocele

Genetic Tests for Myelomeningocele

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Anatomical Context for Myelomeningocele

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MalaCards organs/tissues related to Myelomeningocele:

33
Spinal cord, Brain, Skin, Bone, Testes, Heart, Smooth muscle

Animal Models for Myelomeningocele or affiliated genes

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MGI Mouse Phenotypes related to Myelomeningocele:

38 (show all 17)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.0CBS, CELSR1, PAX3, T, VANGL2
2MP:00053959.0CELSR1, MTHFD1, VANGL2
3MP:00053778.7CELSR1, PAX3, SCRIB, VANGL1, VANGL2
4MP:00053818.7DACT1, PAX3, SCRIB, T, VANGL2
5MP:00053908.6CELSR1, DACT1, MTHFR, PAX3, T, VANGL2
6MP:00030128.6DACT1, MTHFR, PAX3, PRICKLE1, T, VANGL2
7MP:00053918.4CBS, CELSR1, MTHFR, PAX3, SCRIB, VANGL2
8MP:00053678.4CBS, DACT1, PAX3, SCRIB, T, VANGL2
9MP:00053888.1CBS, CELSR1, PAX3, SCRIB, VANGL1, VANGL2
10MP:00053897.6CBS, DACT1, MTHFR, SCRIB, T, VANGL1
11MP:00053857.4CBS, DACT1, MTHFD1, PAX3, T, VANGL1
12MP:00053766.7CBS, CELSR1, MTHFD1, MTHFR, MTRR, PAX3
13MP:00053716.5CBS, CELSR1, DACT1, MTHFD1, MTHFR, PAX3
14MP:00053806.3CBS, CELSR1, DACT1, MTHFD1, PAX3, PRICKLE1
15MP:00036316.0CELSR1, DACT1, MTHFD1, MTHFR, PAX3, PRICKLE1
16MP:00107686.0CBS, CELSR1, DACT1, MTHFD1, MTHFR, PAX3
17MP:00053785.8CBS, CELSR1, DACT1, MTHFD1, MTHFR, MTRR

Publications for Myelomeningocele

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Articles related to Myelomeningocele:

(show top 50)    (show all 581)
idTitleAuthorsYear
1
Physical model from 3D ultrasound and magnetic resonance imaging scan data reconstruction of lumbosacral myelomeningocele in a fetus with Chiari II malformation. (25686895)
2015
2
An Application of Keystone Perforator Island Flap for Closure of Lumbosacral Myelomeningocele Defects. (26418773)
2015
3
Clinical and ultrasonographic criteria for using ventriculoperitoneal shunts in newborns with myelomeningocele. (26352494)
2015
4
Who needs surgery for pediatric myelomeningocele? A retrospective study and literature review. (25029586)
2014
5
The Role of Echocardiography in the Intraoperative Management of the Fetus Undergoing Myelomeningocele Repair. (25059830)
2014
6
Muscle ultrasound quantifies segmental neuromuscular outcome in pediatric myelomeningocele. (24210858)
2014
7
Improvement of motor function and decreased need for postnatal shunting in children who had undergone intrauterine myelomeningocele repair. (24141440)
2013
8
Genetic studies of myelomeningocele. (24013315)
2013
9
Family-based association study between SLC2A1, HK1, and LEPR polymorphisms with myelomeningocele in Chile. (23427181)
2013
10
Intrauterine myelomeningocele repair postnatal results and follow-up at 3.5 years of age--initial experience from a single reference service in Brazil. (22205531)
2012
11
Psycholinguistic and scholastic abilities in children with myelomeningocele. (22231053)
2011
12
Prenatal versus postnatal repair of myelomeningocele. (21714661)
2011
13
Morphometric analysis of posterior fossa after in utero myelomeningocele repair. (21456906)
2011
14
Treatment of Gibbus deformity associated with myelomeningocele in the young child with use of the vertical expandable prosthetic titanium rib (VEPTR): a case report. (20844164)
2010
15
Anesthetic management in intrauterine surgery to evaluate an experimental model of myelomeningocele in non human primates (Macaca mulatta). (20498944)
2010
16
Transanal irrigation in myelomeningocele children: an alternative, safe and valid approach for neurogenic constipation. (20084075)
2010
17
Bone mineral density in children with myelomeningocele. (18811711)
2009
18
Bulbar urethral ligation for managing persistent urinary incontinence in young men with myelomeningocele. (19245443)
2009
19
Editorial comment. Effect of pelvic floor interferential electrostimulation on urodynamic parameters and incontinency of children with myelomeningocele and detrusor overactivity. (19646616)
2009
20
Early results of the Ponseti method for the treatment of clubfoot associated with myelomeningocele. (19487512)
2009
21
Oral findings and dental care in a patient with myelomeningocele: case report of a 3-year-old child. (20126914)
2009
22
Tissue expansion technique for closure of myelomeningocele. (21887171)
2009
23
Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently impacts on brain stem function. (19569004)
2008
24
Morphologic analysis of the neuromuscular development of the anorectal unit in fetal rats with retinoic acid induced myelomeningocele. (18063303)
2008
25
Complications of clean intermittent catheterization in young females with myelomeningocele: 10 to 19 years of followup. (17632181)
2007
26
New anchoring method for tarsal tendon transfers in myelomeningocele patients. (19308534)
2007
27
Intrauterine surgery in myelomeningocele. (17716961)
2007
28
Double myelomeningocele in a neonate: Case report and review of the literature. (15936872)
2006
29
Evaluation of sexual function in young men with spina bifida and myelomeningocele using the International Index of Erectile Function. (16504267)
2006
30
Repeated intradetrusor botulinum toxin type A in children with neurogenic bladder due to myelomeningocele. (16469632)
2006
31
Maternal diabetes and neural tube defects: prenatal diagnosis of lumbosacral myelomeningocele, ventriculomegaly, Arnold-Chiari malformation and foot deformities in a pregnancy with poor maternal metabolic control, and review of the literature. (16259331)
2005
32
Adult tethered cord syndrome in patients with postrepair myelomeningocele: an evidence-based outcome study. (16156223)
2005
33
Impact of maternal-fetal surgery for myelomeningocele on the progression of ventriculomegaly in utero. (16150266)
2005
34
Prescribing the reciprocal gait orthosis for myelomeningocele children: a different approach and clinical outcome. (15204581)
2004
35
Kyphectomy in myelomeningocele with a modified Dunn-McCarthy technique followed by an anterior inlayed strut graft. (14714245)
2004
36
Prenatal intervention for urinary obstruction and myelomeningocele. (15707516)
2004
37
Embryology of myelomeningocele and anencephaly. (15209484)
2004
38
Grip force parameters in precision grip of individuals with myelomeningocele. (12647926)
2003
39
Myelomeningocele: prenatal evaluation--comparison between transabdominal US and MR imaging. (12714679)
2003
40
Maternal-fetal surgery for treatment of myelomeningocele. (12696793)
2003
41
The immunohistochemical profile of the myelomeningocele placode: is the placode normal? (14512686)
2003
42
Correction of hindbrain herniation and anatomy of the vermis after in utero repair of myelomeningocele in sheep. (12632366)
2003
43
In utero meconium exposure increases spinal cord necrosis in arat model of myelomeningocele. (12194146)
2002
44
Postoperative sudden death in two adolescents with myelomeningocele and unrecognized arrhythmogenic right ventricular dysplasia. (11465566)
2001
45
Treatment of neuropathic bladder using botulinum toxin A in a 1-year-old child with myelomeningocele. (11793122)
2001
46
Ambulation in Patients with Myelomeningocele: A 12-Year Follow-up. (17053651)
2001
47
Oval-shaped cornea, lens duplication, and optic nerve hypoplasia associated with myelomeningocele. (11124675)
2000
48
Peripheral chemoreceptor function in children with myelomeningocele and Arnold-Chiari malformation type 2. (7634879)
1995
49
Bladder-outlet reconstruction in neurogenic bladder due to myelomeningocele. (3337968)
1988
50
Klippel-Feil syndrome. Syringomyelia, diastematomyelia, and myelomeningocele--one disease? (13896922)
1961

Variations for Myelomeningocele

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Expression for genes affiliated with Myelomeningocele

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Search GEO for disease gene expression data for Myelomeningocele.

Pathways for genes affiliated with Myelomeningocele

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GO Terms for genes affiliated with Myelomeningocele

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Cellular components related to Myelomeningocele according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lateral plasma membraneGO:00163289.3VANGL1, VANGL2

Biological processes related to Myelomeningocele according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1homocysteine metabolic processGO:005066710.4CBS, MTHFR
2homocysteine catabolic processGO:004341810.2CBS, MTRR
3sulfur amino acid metabolic processGO:000009610.1CBS, MTRR
4establishment of planar polarityGO:000173610.1CELSR1, VANGL2
5apical protein localizationGO:004517610.1CELSR1, VANGL2
6establishment of body hair planar orientationGO:004810510.1CELSR1, VANGL2
7orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesisGO:006048810.1CELSR1, VANGL2
8planar dichotomous subdivision of terminal units involved in lung branching morphogenesisGO:006048910.1CELSR1, VANGL2
9lateral sprouting involved in lung morphogenesisGO:006049010.1CELSR1, VANGL2
10planar cell polarity pathway involved in neural tube closureGO:009017910.1CELSR1, VANGL2
11regulation of actin cytoskeleton organizationGO:003295610.0CELSR1, VANGL2
12post-anal tail morphogenesisGO:003634210.0T, VANGL2
13tetrahydrofolate interconversionGO:00359999.9MTHFD1, MTHFR
14transsulfurationGO:00193469.8CBS, MTHFD1
15anterior/posterior pattern specificationGO:00099529.7CELSR1, T, VANGL2
16hair follicle developmentGO:00019429.6CELSR1, VANGL2
17methionine metabolic processGO:00065559.5MTHFD1, MTHFR, MTRR
18methionine biosynthetic processGO:00090869.4MTHFD1, MTHFR, MTRR
19vitamin metabolic processGO:00067669.1MTHFD1, MTHFR, MTRR
20water-soluble vitamin metabolic processGO:00067679.1MTHFD1, MTHFR, MTRR
21folic acid metabolic processGO:00466559.1MTHFD1, MTHFR, MTRR
22wound healingGO:00420608.8CELSR1, SCRIB, VANGL2
23oxidation-reduction processGO:00551148.6CBS, MTHFD1, MTHFR, MTRR
24neural tube closureGO:00018437.6CELSR1, MTHFD1, PAX3, PRICKLE1, SCRIB, T

Molecular functions related to Myelomeningocele according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1modified amino acid bindingGO:00723419.8CBS, MTHFR
2NADP bindingGO:00506619.7MTHFR, MTRR

Sources for Myelomeningocele

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet