MCID: MYL020
MIFTS: 50

Myelomeningocele malady

Categories: Rare diseases, Neuronal diseases, Fetal diseases

Aliases & Classifications for Myelomeningocele

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Sources:
2CDC, 11Disease Ontology, 13DISEASES, 26GTR, 29ICD10, 30ICD10 via Orphanet, 38MeSH, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS
See all MalaCards sources

Summaries for Myelomeningocele

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CDC:2 Spina bifida is a major birth defect of a person’s spine. With good quality medical care people with spina bifida can reach their full potential. If you have spina bifida, or know someone who does, it’s important to get the facts so that you can make the best possible health care choices.

MalaCards based summary: Myelomeningocele, also known as meningomyelocele, is related to neural tube defects, folate-sensitive and spina bifida aperta. An important gene associated with Myelomeningocele is MTHFR (Methylenetetrahydrofolate Reductase), and among its related pathways are Folate-Alcohol and Cancer Pathway and Wnt / Hedgehog / Notch. Affiliated tissues include spinal cord, brain and bone, and related mouse phenotypes are craniofacial and hearing/vestibular/ear.

Disease Ontology:11 A spina bifida characterized by protrusion of the spinal cord through an opening, covered by meningeal membranes.

Related Diseases for Myelomeningocele

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Diseases related to Myelomeningocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 108)
idRelated DiseaseScoreTop Affiliating Genes
1neural tube defects, folate-sensitive30.5MTHFD1, MTHFR, MTR, MTRR
2spina bifida aperta28.7MTHFD1, MTHFR, T, VANGL1, VANGL2
3neural tube defects26.5CBS, CELSR1, DACT1, MTHFD1, MTHFR, MTR
4renal agenesis meningomyelocele mullerian defect11.8
5chiari malformation type ii11.3
6chiari malformation11.2
7schwartz cohen-addad lambert syndrome10.8
8heterotaxy, visceral, 1, x-linked10.8
9critical limb ischemia10.2CELSR1, DACT1, SCRIB
10hydrocephalus10.2
11functional diarrhea10.2CBS, MTHFR
12candidiasis, familial, 6, autosomal dominant10.1CBS, MTHFR
13homocystinuria due to mthfr deficiency10.1MTHFR, MTR
14noma10.1MTHFD1, MTHFR
15neurogenic bladder10.1
16cervicitis10.1
17serine deficiency10.0MTHFR, MTR
18vaginal adenoma10.0PRICKLE1, VANGL1, VANGL2
19scoliosis10.0
20methylmalonic aciduria and homocystinuria type cblg10.0MTHFR, MTR
21congenital intrinsic factor deficiency10.0MTR, MTRR
22x-linked disease9.9MTR, MTRR
23dysferlinopathy9.9MTR, MTRR
24neurogenic bowel9.8
25cerebritis9.8
26diastematomyelia9.8
27clubfoot9.8
28apraxia9.8CBS, MTHFR
29homocystinuria due to defect in methylation cbl g9.8MTHFR, MTR, MTRR
30x-linked congenital generalized hypertrichosis9.8MTHFR, MTR, MTRR
31agammaglobulinemia 29.7MTHFR, MTR, MTRR
32spinal cord injury9.7
33meningocele9.7
34constipation9.7
35syringomyelia9.7
36strabismus9.7
37encephalocele9.7
38tethered cord syndrome9.7
39syringohydromyelia9.7
40exostosis9.7MTHFD1, MTR
41obesity9.6
42focal dermal hypoplasia9.6
43anencephaly9.6
44cerebral palsy9.6
45tethered spinal cord syndrome9.6
46choroiditis9.6
47urethritis9.6
48epilepsy9.6
49teratoma9.6
50congenital diaphragmatic hernia9.6

Graphical network of the top 20 diseases related to Myelomeningocele:



Diseases related to myelomeningocele

Symptoms for Myelomeningocele

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Drugs & Therapeutics for Myelomeningocele

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Drugs for Myelomeningocele (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholineapprovedPhase 477651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
2
Oxybutyninapproved, investigationalPhase 4675633-20-54634
Synonyms:
1508-65-2 (hydrochloride)
4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
4-(diethylamino)-2-butynyl-alpha-cyclohexyl-alpha-hydroxybenzeneacetate
4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate
4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
4-(diethylamino)but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate
4-Diethylamino-2-butinyl alpha-cyclohexylmandelat
4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
5633-20-5
AC-2153
AC1L1ILV
BPBio1_000214
BRD-A65013509-003-03-8
BSPBio_000194
Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester
C07360
CCRIS 1923
CHEBI:7856
CHEMBL1231
CID4634
Cyclohexaneglycolic acid, .alpha.-phenyl-, 4-(diethylamino)-2-butynyl ester
Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester
Cystrin
D00465
DB01062
Ditropan
Ditropan, Lyrinel XL, Oxytrol, Oxybutynin
FT-0082890
HSDB 3270
I06-2117
L000923
LS-28714
 
Lopac0_000923
MolPort-003-849-741
NCGC00015767-06
NCGC00089795-02
Oxibutinina
Oxibutinina [INN-Spanish]
Oxibutyninum
Oxybutinin
Oxybutynin
Oxybutynin (USAN/INN)
Oxybutynin Base
Oxybutynin Chloride
Oxybutynin Hydrochloride
Oxybutynin [USAN:INN:BAN]
Oxybutynin topical gel
Oxybutynine
Oxybutynine [INN-French]
Oxybutyninum
Oxybutyninum [INN-Latin]
Oxytrol
Oxytrol (TN)
Pollakisu
Prestwick0_000287
Prestwick1_000287
Prestwick2_000287
Prestwick3_000287
S1754_Selleck
SPBio_002413
Transdermal patch
UNII-K9P6MC7092
oxybutynin
oxybutynin topical gel
transdermal patch
3onabotulinumtoxinAPhase 4626
4abobotulinumtoxinAPhase 4626
5Botulinum ToxinsPhase 4669
6Neurotransmitter AgentsPhase 4, Phase 217734
7Peripheral Nervous System AgentsPhase 422776
8Botulinum Toxins, Type APhase 4630
9Cholinergic AgentsPhase 4, Phase 23846
10incobotulinumtoxinAPhase 4635
11Neuromuscular AgentsPhase 41129
12
Darifenacinapproved, investigationalPhase 222133099-04-4444031
Synonyms:
(S)-1-(2-(2,3-Dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide
(S)-1-(2-(2,3-dihydro-5-Benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide
133099-04-4
2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide
2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide
AC-302
AC1L9FKY
CHEBI:391960
CHEMBL1346
CID444031
D03654
 
DB00496
Darifenacin
Darifenacin (USAN/INN)
Darifenacina
Darifenacinum
Darifénacine
Emselex
Enablex
LS-187359
MolPort-005-943-011
NCGC00168775-01
STOCK6S-73577
darifenacin
13Cholinergic AntagonistsPhase 21658
14Muscarinic AntagonistsPhase 21134
15Methenamine hippuratePhase 19
16MethenaminePhase 19
17AcidophilusNutraceuticalPhase 1518
18
Mentholapproved23532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
19ColaNutraceutical1881

Interventional clinical trials:

(show all 18)
idNameStatusNCT IDPhase
1Effect of Botulinum Toxin in Neurogenic Bladders in Children With MyelomeningoceleUnknown statusNCT00175123Phase 4
2Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord LesionsCompletedNCT01208584Phase 4
32 Week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Yrs) With Neurogenic Detrusor OveractivitySuspendedNCT00712322Phase 2
4Bacteriuria Eradication Through ProbioticsUnknown statusNCT00717600Phase 1
5Fetoscopic Meningomyelocele Repair StudyRecruitingNCT02230072Phase 1
6Reciprocating Gait Orthoses for Paraplegia PatientsUnknown statusNCT02227407
7Management of Myelomeningocele Study (MOMS)CompletedNCT00060606
8Feasibility of the Portable YouGrabber SystemCompletedNCT02368223
9Prenatal Surgical Repair of Fetal MyelomeningoceleRecruitingNCT01983345
10Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0RecruitingNCT02509377
11Extended Criteria For Fetal Myelomeningocele RepairRecruitingNCT02664207
12Evaluation of Hysterotomy Site After Open Fetal SurgeryRecruitingNCT02493062
13Extramembranous and Interosseous Technique of Tibialis Posterior Tendon TransferRecruitingNCT01751503
14Retrograde Colonic Irrigation to Manage Spina Bifida Functional Digestive Sequelae: a Multicenter, Prospective, Randomized Controlled TrialRecruitingNCT02361450
15Self-esteem and Neuro-urological Follow-up in Patients With Spina Bifida or Spinal Cord InjuryRecruitingNCT01606618
16Psychosocial Adjustment of Adolescents With Spina BifidaActive, not recruitingNCT00891891
17Reliability of the Melbourne AssessmentActive, not recruitingNCT02595411
18Prenatal Endoscopic Repair of Fetal Spina BifidaNot yet recruitingNCT02390895

Search NIH Clinical Center for Myelomeningocele


Cochrane evidence based reviews: meningomyelocele

Genetic Tests for Myelomeningocele

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Genetic tests related to Myelomeningocele:

id Genetic test Affiliating Genes
1 Myelomeningocele26

Anatomical Context for Myelomeningocele

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MalaCards organs/tissues related to Myelomeningocele:

35
Spinal cord, Brain, Bone, Skin, Colon, Heart, Smooth muscle

Animal Models for Myelomeningocele or affiliated genes

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Publications for Myelomeningocele

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Articles related to Myelomeningocele:

(show top 50)    (show all 647)
idTitleAuthorsYear
1
Ultrasound functional evaluation of fetuses with myelomeningocele: study of the interpretation of results. (27997256)
2017
2
Surgical Management of Hip Problems in Myelomeningocele: A Review Article. (27517062)
2016
3
Latex sensitization in patients with myelomeningocele undergoing urological procedures: prevalence and associated factors. (27033690)
2016
4
Correlation of mortality with lesion level in patients with myelomeningocele: a population-based study. (27911247)
2016
5
Trends in epidemiology and hospitalization utilization for myelomeningocele repair from 2000 to 2009. (27112355)
2016
6
Fetal Heart Rate during in Utero Myelomeningocele Repair: Effect of Anesthesia and Analgesia. (27509040)
2016
7
Clinical and ultrasonographic criteria for using ventriculoperitoneal shunts in newborns with myelomeningocele. (26352494)
2015
8
Surgical results of strabismus correction in patients with myelomeningocele. (25714531)
2015
9
OP-21 QUALITY OF LIFE BEFORE AND AFTER BIOFEEDBACK TREATMENT IN MYELOMENINGOCELE PATIENT. (26439562)
2015
10
Bladder Function After Fetal Surgery for Myelomeningocele. (26416930)
2015
11
Muscle ultrasound quantifies segmental neuromuscular outcome in pediatric myelomeningocele. (24210858)
2014
12
Bladder Changes After Several Coverage Modalities in the Surgically Induced Model of Myelomeningocele in Lambs. (24126194)
2014
13
Predictors of the need for cerebrospinal fluid diversion in patients with myelomeningocele. (24877604)
2014
14
Family-based association study between SLC2A1, HK1, and LEPR polymorphisms with myelomeningocele in Chile. (23427181)
2013
15
Treatment of spinal deformity associated with myelomeningocele in young children with the use of the four-rib construct. (23787773)
2013
16
Fetal surgery for myelomeningocele: a critical appraisal. (23572465)
2013
17
Fetal myelomeningocele repair: a new standard of care. (22840506)
2012
18
Open fetal surgery for myelomeningocele. (22380954)
2012
19
Prenatal versus postnatal repair of myelomeningocele. (21714661)
2011
20
Latencies obtained of the somatosensory evoked potentials of the median and tibial nerve in rhesus monkey undergoing intrauterine laminectomy to simulate myelomeningocele. (22380994)
2011
21
Decreased incidence of myelomeningocele at birth: effect of folic acid recommendations or prenatal diagnostics? (21552997)
2011
22
Repeated Botulinum-A toxin injection in the treatment of neuropathic bladder dysfunction and poor bladder compliance in children with myelomeningocele. (21674597)
2011
23
Transanal irrigation in myelomeningocele children: an alternative, safe and valid approach for neurogenic constipation. (20084075)
2010
24
Local and regional flap closure in myelomeningocele repair: a 15-year review. (20195618)
2010
25
Bone mineral density in children with myelomeningocele. (18811711)
2009
26
Bulbar urethral ligation for managing persistent urinary incontinence in young men with myelomeningocele. (19245443)
2009
27
Oral findings and dental care in a patient with myelomeningocele: case report of a 3-year-old child. (20126914)
2009
28
Independence in the toilet activity in children and adolescents with myelomeningocele--managing clean intermittent catheterization in a hospital setting. (19604172)
2009
29
Primary closure of large thoracolumbar myelomeningocele with bilateral latissimus dorsi flaps. (19338414)
2009
30
Vascular and apoptotic changes in the placode of myelomeningocele mice during the final stages of in utero development. (18671624)
2008
31
Complications of clean intermittent catheterization in young females with myelomeningocele: 10 to 19 years of followup. (17632181)
2007
32
New anchoring method for tarsal tendon transfers in myelomeningocele patients. (19308534)
2007
33
Intrauterine surgery in myelomeningocele. (17716961)
2007
34
Does a myelomeningocele sac compared to no sac result in decreased postnatal leg function following maternal fetal surgery for spina bifida aperta? (17556822)
2007
35
Double myelomeningocele in a neonate: Case report and review of the literature. (15936872)
2006
36
Evaluation of sexual function in young men with spina bifida and myelomeningocele using the International Index of Erectile Function. (16504267)
2006
37
Influence of family environment on language outcomes in children with myelomeningocele. (16101655)
2005
38
Amniotic fluid brain-specific proteins are biomarkers for spinal cord injury in experimental myelomeningocele. (16190875)
2005
39
Kyphectomy in myelomeningocele with a modified Dunn-McCarthy technique followed by an anterior inlayed strut graft. (14714245)
2004
40
Prenatal intervention for urinary obstruction and myelomeningocele. (15707516)
2004
41
Botulinum-A toxin injection into the detrusor: a safe alternative in the treatment of children with myelomeningocele with detrusor hyperreflexia. (14713840)
2004
42
Grip force parameters in precision grip of individuals with myelomeningocele. (12647926)
2003
43
Maternal-fetal surgery for treatment of myelomeningocele. (12696793)
2003
44
Correction of hindbrain herniation and anatomy of the vermis after in utero repair of myelomeningocele in sheep. (12632366)
2003
45
Fetal surgery for myelomeningocele: panacea or peril? (12557043)
2003
46
Preservation of renal function in children with myelomeningocele managed with basic newborn evaluation and close followup. (12478177)
2003
47
Treatment of neuropathic bladder using botulinum toxin A in a 1-year-old child with myelomeningocele. (11793122)
2001
48
Ambulation in Patients with Myelomeningocele: A 12-Year Follow-up. (17053651)
2001
49
Peripheral chemoreceptor function in children with myelomeningocele and Arnold-Chiari malformation type 2. (7634879)
1995
50
Bladder-outlet reconstruction in neurogenic bladder due to myelomeningocele. (3337968)
1988

Variations for Myelomeningocele

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Expression for genes affiliated with Myelomeningocele

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Search GEO for disease gene expression data for Myelomeningocele.

Pathways for genes affiliated with Myelomeningocele

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Pathways related to Myelomeningocele according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.9CBS, MTHFR
29.4PAX3, SCRIB, VANGL1
3
Show member pathways
9.4CBS, MTHFR, MTR
4
Show member pathways
9.4MTHFR, MTRR
5
Show member pathways
9.1MTR, MTRR
69.1MTR, MTRR
7
Show member pathways
8.9DACT1, PRICKLE1, SCRIB, VANGL2
8
Show member pathways
8.8CBS, MTR, MTRR
9
Show member pathways
8.3MTHFD1, MTHFR, MTR, MTRR
10
Show member pathways
8.0CBS, MTHFD1, MTHFR, MTR, MTRR

GO Terms for genes affiliated with Myelomeningocele

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Cellular components related to Myelomeningocele according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00058296.9CBS, DACT1, MTHFD1, MTHFR, MTR, MTRR

Biological processes related to Myelomeningocele according to GeneCards Suite gene sharing:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1planar dichotomous subdivision of terminal units involved in lung branching morphogenesisGO:006048910.2CELSR1, VANGL2
2lateral sprouting involved in lung morphogenesisGO:006049010.2CELSR1, VANGL2
3orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesisGO:006048810.2CELSR1, VANGL2
4planar cell polarity pathway involved in neural tube closureGO:009017910.2CELSR1, VANGL2
5establishment of body hair planar orientationGO:004810510.2CELSR1, VANGL2
6tetrahydrofolate interconversionGO:003599910.2MTHFD1, MTHFR
7transsulfurationGO:001934610.1CBS, MTHFD1
8post-anal tail morphogenesisGO:003634210.1T, VANGL2
9establishment of planar polarityGO:000173610.0CELSR1, VANGL2
10homocysteine catabolic processGO:004341810.0CBS, MTRR
11hair follicle developmentGO:00019429.9CELSR1, VANGL2
12homocysteine metabolic processGO:00506679.8CBS, MTHFR
13apical protein localizationGO:00451769.8CELSR1, VANGL2
14anterior/posterior pattern specificationGO:00099529.7CELSR1, T, VANGL2
15sulfur amino acid metabolic processGO:00000969.7MTR, MTRR
16cobalamin metabolic processGO:00092359.7MTR, MTRR
17methionine metabolic processGO:00065559.5MTHFD1, MTHFR, MTRR
18Wnt signaling pathway, planar cell polarity pathwayGO:00600719.3CELSR1, PRICKLE1, VANGL1, VANGL2
19methionine biosynthetic processGO:00090869.1MTHFD1, MTR, MTRR
20wound healingGO:00420609.0CELSR1, SCRIB, VANGL2
21folic acid metabolic processGO:00466558.9MTHFD1, MTHFR, MTRR
22oxidation-reduction processGO:00551148.5CBS, MTHFD1, MTHFR, MTRR
23neural tube closureGO:00018438.3CELSR1, MTHFD1, PRICKLE1, SCRIB, T, VANGL2

Molecular functions related to Myelomeningocele according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1modified amino acid bindingGO:007234110.4CBS, MTHFR
2NADP bindingGO:00506619.8MTHFR, MTRR
3protein bindingGO:00055155.2CBS, CELSR1, DACT1, MTHFD1, MTR, MTRR

Sources for Myelomeningocele

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
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45NDF-RT
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49Novoseek
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52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet