MCID: MYL015
MIFTS: 25

Myeloproliferative Disorder with Eosinophilia malady

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Summaries for Myeloproliferative Disorder with Eosinophilia

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47OMIM, 33MalaCards
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MalaCards: Myeloproliferative Disorder with Eosinophilia is related to eosinophilia and myeloproliferative disorder. An important gene associated with Myeloproliferative Disorder with Eosinophilia is PDGFRB (platelet-derived growth factor receptor, beta polypeptide), and among its related pathways are Pathways in cancer and Signaling by FGFR. The compounds dasatinib and ganglioside have been mentioned in the context of this disorder. Affiliated tissues include t cells.

Description from OMIM:47 131440

Aliases & Classifications for Myeloproliferative Disorder with Eosinophilia

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47OMIM
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Aliases & Descriptions:

myeloproliferative disorder with eosinophilia 47


Related Diseases for Myeloproliferative Disorder with Eosinophilia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Myeloproliferative Disorder with Eosinophilia:



Diseases related to myeloproliferative disorder with eosinophilia

Symptoms for Myeloproliferative Disorder with Eosinophilia

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47OMIM
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Symptoms by clinical synopsis from OMIM:

131440

Clinical features from OMIM:

131440

Drugs & Therapeutics for Myeloproliferative Disorder with Eosinophilia

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Myeloproliferative Disorder with Eosinophilia

Search NIH Clinical Center for Myeloproliferative Disorder with Eosinophilia

Genetic Tests for Myeloproliferative Disorder with Eosinophilia

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Anatomical Context for Myeloproliferative Disorder with Eosinophilia

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33MalaCards
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MalaCards organs/tissues related to Myeloproliferative Disorder with Eosinophilia:

33
T cells

Animal Models for Myeloproliferative Disorder with Eosinophilia or affiliated genes

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Publications for Myeloproliferative Disorder with Eosinophilia

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52PubMed
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Articles related to Myeloproliferative Disorder with Eosinophilia:

idTitleAuthorsYear
1
Congenital and childhood myeloproliferative disorders with eosinophilia responsive to imatinib. (22488677)
2012
2
Myeloproliferative disorder with eosinophilia and ETV6-ABL gene rearrangement: efficacy of second-generation tyrosine kinase inhibitors. (19394693)
2009
3
Complete haematological and cytogenetic response to interferon alpha-2a of a myeloproliferative disorder with eosinophilia associated with a unique t(4;7) aberration. (10741923)
2000
4
Cytogenetic response induced by interferon alpha in the myeloproliferative disorder with eosinophilia, T cell lymphoma and the chromosomal translocation t(8;13)(p11;q12) (9639434)
1998
5
A myeloproliferative disorder with eosinophilia associated with a unique translocation (3;5). (8943895)
1996

Variations for Myeloproliferative Disorder with Eosinophilia

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Expression for genes affiliated with Myeloproliferative Disorder with Eosinophilia

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myeloproliferative Disorder with Eosinophilia

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Pathways for genes affiliated with Myeloproliferative Disorder with Eosinophilia

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50PathCards, 30KEGG, 55Reactome, 60Thomson Reuters, 5Cell Signaling Technology
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Compounds for genes affiliated with Myeloproliferative Disorder with Eosinophilia

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45Novoseek, 51PharmGKB, 11DrugBank, 29IUPHAR, 61Tocris Bioscience, 3BitterDB, 24HMDB
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Compounds related to Myeloproliferative Disorder with Eosinophilia according to GeneCards/GeneDecks:

(show all 25)
idCompoundScoreTop Affiliating Genes
1dasatinib45 51 1111.7PDGFRB, BCR
2ganglioside459.7BCR, PDGFRB
3gp 130459.7BCR, PDGFRB
4inositol 1,4,5 trisphosphate459.6BCR, PDGFRB
5imatinib45 51 1111.6PDGFRB, BCR
6phenylalanine459.6BCR, PDGFRB
7phosphotyrosine459.5PDGFRB, BCR
8busulfan45 51 1111.5BCR, IFNA2
9rituximab45 51 1111.5BCR, IFNA2
10cytarabine45 51 1111.5BCR, IFNA2
11ly294002459.4PDGFRB, BCR
12cyclophosphamide45 51 1111.4BCR, IFNA2
13phosphoinositide459.4PDGFRB, BCR
14genistein45 29 61 3 24 1114.3BCR, PDGFRB
15leucine459.3PDGFRB, BCR
165fluorouracil459.3PDGFRB, IFNA2
17agar459.3IFNA2, PDGFRB
18ribonucleic acid459.2PDGFRB, IFNA2
19methionine459.2IFNA2, PDGFRB
20thymidine45 2410.0BCR, IFNA2
21oxygen45 249.9PDGFRB, BCR, IFNA2
22cysteine458.8PDGFRB, BCR, IFNA2
23lipid458.8PDGFRB, BCR, IFNA2
24tyrosine458.8IFNA2, BCR, PDGFRB
25cisplatin45 51 61 1111.7PDGFRB, IFNA2

GO Terms for genes affiliated with Myeloproliferative Disorder with Eosinophilia

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16Gene Ontology
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Biological processes related to Myeloproliferative Disorder with Eosinophilia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein autophosphorylationGO:0467779.3PDGFRB, BCR
2platelet-derived growth factor receptor signaling pathwayGO:0480089.2PDGFRB, BCR
3peptidyl-tyrosine phosphorylationGO:0181089.0PDGFRB, BCR

Molecular functions related to Myeloproliferative Disorder with Eosinophilia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein tyrosine kinase activityGO:0047139.3PDGFRB, BCR

Products for genes affiliated with Myeloproliferative Disorder with Eosinophilia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Myeloproliferative Disorder with Eosinophilia

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet