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MCID: MYB001
MIFTS: 32

Myoblastoma malady

Cancer category
5 genes, 15 tissues, 16 related diseases, clinical trials.

Summaries for Myoblastoma

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33MalaCards
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MalaCards: Myoblastoma, also known as benign granular cell tumor, is related to granular cell tumor and malignant granular cell myoblastoma. An important gene associated with Myoblastoma is SOX8 (SRY (sex determining region Y)-box 8). The compounds spec-t and malondialdehyde have been mentioned in the context of this disorder. Affiliated tissues include skin, tongue and brain.

Aliases & Classifications for Myoblastoma

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Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 40NCIt, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer


Aliases & Descriptions:

myoblastoma 8 10 61
benign granular cell tumor 8


External Ids:

Disease Ontology8 DOID:5039
NCIt40 C3252
MeSH35 D009379

Related Diseases for Myoblastoma

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Myoblastoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 16)
idRelated DiseaseScoreTop Affiliating Genes
1granular cell tumor10.7
2malignant granular cell myoblastoma10.6
3granular cell carcinoma10.4
4myoma10.2
5congenital epulis10.1
6mediastinal granular cell myoblastoma10.1
7squamous cell carcinoma10.1
8merkel cell carcinoma10.0ENO2
9granuloma inguinale10.0
10polyhydramnios10.0
11bronchogenic carcinoma10.0
12chromophobe adenoma10.0
13ganglioneuroma10.0
14breast granular cell tumor10.0
15adenocarcinoma10.0
16adenoma10.0

Graphical network of diseases related to Myoblastoma:



Diseases related to myoblastoma

Clinical Features for Myoblastoma

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Drugs & Therapeutics for Myoblastoma

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Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Myoblastoma

Drug clinical trials:

Search ClinicalTrials for Myoblastoma

Search NIH Clinical Center for Myoblastoma

Search CenterWatch for Myoblastoma

Genetic Tests for Myoblastoma

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Anatomical Context for Myoblastoma

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Sources:
33MalaCards
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MalaCards organs/tissues related to Myoblastoma:

33
Skin, Tongue, Brain, Lung, Uterus, Small intestine, Colon, Pancreas, Thyroid, Breast, Cervix, Trachea, Bronchial epithelium, Appendix, Pituitary

Animal Models for Myoblastoma or affiliated genes

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Sources:
28inGenious Targeting Laboratory
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Publications for Myoblastoma

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Sources:
51PubMed
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Articles related to Myoblastoma:

(show top 50)    (show all 419)
idTitleAuthorsYear
1
C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression. (18434429)
2008
2
Congenital granular-cell myoblastoma. (1398721)
1992
3
Granular cell myoblastoma of the supraglottis. (2539423)
1989
4
Polyhydramnios caused by giant alveolar granular cell myoblastoma. (3022540)
1986
5
Granular cell myoblastoma of the breast. (2991509)
1985
6
Intracranial trigeminal nerve granular cell myoblastoma. Case report. (6310068)
1983
7
Granular cell myoblastoma in the tongue of a dog: a case report. (6308883)
1983
8
Coexisting granular cell myoblastoma and squamous carcinoma of the bronchus. (6287661)
1982
9
Granular cell myoblastoma, a rare localization in the trachea. A case report. (6280271)
1982
10
Granular cell myoblastoma of the hands. Report of a child with multiple tumors. (6255894)
1980
11
Granular cell myoblastoma of the bronchus. (6246643)
1980
12
Granular cell myoblastoma: a cause of biliary obstruction. (203183)
1978
13
Cerebral granular cell tumor (myoblastoma) in a dog: case report and literature review. (213238)
1978
14
The granular cell myoblastoma. (197457)
1977
15
Granular cell myoblastoma of the common bile duct: report of a case and review of the literature. (173012)
1975
16
Granular cell myoblastoma of the hard palate: report of case. (167143)
1975
17
Giant cell myoblastoma. (4377738)
1974
18
Granular cell myoblastoma of the trachea. Response to radiation therapy. (4333188)
1972
19
Granular cell myoblastoma of the pituitary. Case report. (4341861)
1972
20
Retrobulbar granular cell myoblastoma. (4345901)
1972
21
Endobronchial granular cell myoblastoma. A report of three cases and review of the literature. (4312334)
1970
22
Granular-cell myoblastoma of the oral cavity. (4312944)
1970
23
Ultrastructure of granular cell myoblastoma. (4322544)
1970
24
Granular cell myoblastoma of the eye. Case report. (4305121)
1969
25
'Granular-cell myoblastoma' in the horse. A report of 4 cases. (4304683)
1968
26
Case report: granular cell myoblastoma. (4296090)
1968
27
Diagnosis of granular cell myoblastoma by fine-needle aspiration biopsy. (4297295)
1968
28
Granular cell "myoblastoma" of the breast. (4311259)
1968
29
Granular cell myoblastoma of the pituitary body simulating a chromophobe adenoma. (4287311)
1966
30
GRANULAR CELL MYOBLASTOMA WITH HYPERTROPHIC PULMONARY OSTEOARTHROPATHY IN A MARE. (14317603)
1965
31
Congenital myoblastoma of the newborn: report of a case. (4284017)
1965
32
GRANULAR CELL MYOBLASTOMA OF THE VULVA. (14056179)
1963
33
Granular cell myoblastoma--a misnomer. Electron microscopic and histochemical evidence concerning its Schwann cell derivation and nature (granular cell schwannoma). (13893237)
1962
34
Granular-cell myoblastoma of stomach and colon. (13949103)
1962
35
Granular cell myoblastoma of the bronchus. (13726678)
1961
36
Perianal granular cell myoblastoma. Report of a case. (14438949)
1960
37
Granular cell myoblastoma. (13607912)
1958
38
Primary granular-cell myoblastoma of the bronchus; report of a case with resection. (13463941)
1957
39
Malignant granular-cell myoblastoma. (13268207)
1955
40
Granular cell myoblastoma; report of case in newborn. (14394653)
1955
41
Vulva: myoblastoma. (13149943)
1953
42
Myoblastoma of the buccal mucosa. (14928130)
1952
43
Tumour of the male urethra; "myoblastoma" of the perineal portion of the urethra. (14923177)
1952
44
Malignant granular-cell myoblastoma. (14886903)
1952
45
Granular-cell myoblastoma of common bile duct; report of a case with autopsy findings. (12984946)
1952
46
A morphological and histochemical study of the granular-cell myoblastoma. (12988184)
1952
47
Myoblastoma of the labium majus; report of a case. (14849921)
1951
48
Granular cell myoblastoma (myoblastic myoma, rhabdomyome granulo-cellulaire). (20295396)
1947
49
Myoblastoma. (20341667)
1947
50
Myoblastoma: Case Report. (17858633)
1945

Genetic Variations for Myoblastoma

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Expression for genes affiliated with Myoblastoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myoblastoma

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Pathways for genes affiliated with Myoblastoma

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Compounds for genes affiliated with Myoblastoma

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Sources:
45Novoseek, 24HMDB, 11DrugBank
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Compounds related to Myoblastoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1spec-t459.5ENO2, CHKB
2malondialdehyde459.4ENO2, CHKB
3bicarbonate459.4ENO2, CHKB
4uric acid45 2410.3CHKB, ENO2
5choline45 11 2411.3ENO2, CHKB
6catecholamine459.2ENO2, CHKB
7mannitol45 1110.0ENO2, CHKB

GO Terms for genes affiliated with Myoblastoma

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Products for genes affiliated with Myoblastoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Myoblastoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet
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