Myoblastoma disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Myoblastoma

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³²MalaCards
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MalaCards: Myoblastoma, also known as benign granular cell tumor, is related to granular cell tumor and malignant granular cell myoblastoma. An important gene associated with Myoblastoma is SOX8 (SRY (sex determining region Y)-box 8). The compounds spec-t and malondialdehyde have been mentioned in the context of this disorder. Affiliated tissues include tongue, breast and trachea.

Aliases & Classifications for Myoblastoma

Sources:
⁸Disease Ontology, ¹⁰DISEASES, ⁶⁰UMLS, ³⁹NCIt, ³⁴MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases

Aliases & Descriptions:

myoblastoma ⁸ ¹⁰ ⁶⁰

benign granular cell tumor ⁸

External Ids:

Disease Ontology⁸ DOID:5039

NCIt³⁹ C3252

MeSH³⁴ D009379

UMLS⁶⁰ C0027043

Related Diseases for Myoblastoma

Sources:
¹⁷GeneCards, ¹⁸GeneDecks
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Diseases related to Myoblastoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 33)

id	Related Disease	Score	Top Affiliating Genes
1	granular cell tumor	10.6
2	malignant granular cell myoblastoma	10.5
3	laryngitis	10.3
4	breast disease	10.2
5	myoma	10.1
6	cervicitis	10.1
7	congenital epulis	10.1
8	mediastinal granular cell myoblastoma	10.1
9	epulis	10.1
10	esophagitis	10.1
11	gingivitis	10.1
12	neurofibroma	10.1
13	squamous cell carcinoma	10.1
14	thyroiditis	10.1
15	merkel cell carcinoma	10.0	ENO2
16	cerebritis	9.9
17	granuloma inguinale	9.9
18	polyhydramnios	9.9
19	hydrops of gallbladder	9.9
20	bronchogenic carcinoma	9.9
21	chromophobe adenoma	9.9
22	ganglioneuroma	9.9
23	breast granular cell tumor	9.9
24	adenocarcinoma	9.9
25	adenoma	9.9
26	cholecystitis	9.9
27	histiocytoma	9.9
28	meningioma	9.9
29	meningitis	9.9
30	papillary adenocarcinoma	9.9
31	pituitary adenoma	9.9
32	rectal neoplasm	9.9
33	sarcoidosis	9.9

Graphical network of the top 20 diseases related to Myoblastoma:

Clinical Features for Myoblastoma

Drugs & Therapeutics for Myoblastoma

Sources:
⁵CenterWatch, ⁴¹NIH Clinical Center, ⁶ClinicalTrials
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Approved drugs:

Search CenterWatch for Myoblastoma

Drug clinical trials:

Search ClinicalTrials for Myoblastoma

Search NIH Clinical Center for Myoblastoma

Search CenterWatch for Myoblastoma

Genetic Tests for Myoblastoma

Anatomical Context for Myoblastoma

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³²MalaCards
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MalaCards organs/tissues related to Myoblastoma:

³²

Tongue, Breast, Trachea, Cervix, Lung, Pituitary, Colon, Eye, Thyroid, Pancreas, Skin, Uterus, Brain, Appendix

Animal Models for Myoblastoma or affiliated genes

Publications for Myoblastoma

Sources:
⁵⁰PubMed
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Articles related to Myoblastoma:

(show top 50) (show all 412)

id	Title	Authors	Year
1	Genetic profiling of granular cell myoblastoma. (15346026)	Carinci F.... Pezzetti F.	2004
2	Gingival granular cell myoblastoma in newborns. Report of two cases. (9278111)	RabczyA8ski J.... Kochman A.	1997
3	Granular cell myoblastoma (Abrikossoff tumor) of the chest wall: a never described site of a rare tumor. (7934123)	D'Andrea V.... Di Matteo G.	1994
4	Use of Nd:YAG laser in endobronchial granular cell myoblastoma. (8365322)	Epstein L.J.... Mohsenifar Z.	1993
5	Granular cell myoblastoma: report of a case. (2135233)	Mosier K.... Krutchkoff D.	1990
6	Granular cell myoblastoma of the parapharyngeal space. (2832804)	Remsen K.... Vacca M.	1988
7	Granular cell myoblastoma (GCM): contribution of three cases with genital involvement. (3569328)	Bonilla-Musoles F.... Pellicer A.	1987
8	Large granular-cell myoblastoma of the oesophagus. (3027887)	Hjelms E.... Thomsen P.	1986
9	Granular cell myoblastoma of the vulva in a 6-year-old girl. (3000184)	Brooks G.G.	1985
10	Granular cell myoblastoma of the extrahepatic biliary system. (6329014)	Orenstein H.H.... Nay H.R.	1984
11	CT features of endobronchial granular cell myoblastoma. (6088603)	Coleman B.G.... Stephenson L.W.	1984
12	Malignant granular cell tumour (myoblastoma) of the vulva: report of a case and review of the literature. (7194305)	Robertson A.J.... Guthrie W.	1981
13	Granular cell myoblastoma of the uterine cervix. (6276117)	Copas P.... Diddle A.W.	1981
14	Granular cell myoblastoma. (232887)	Pendse A.K.... Gupta S.P.	1979
15	Granular cell variants in a rat schwannoma. Evidence of neurogenic origin of granular cell tumor (myoblastoma). (220775)	Berman J.J.... Strandberg J.	1978
16	Granular cell myoblastoma of the larynx. (207797)	Kenefick C.	1978
17	Granular myoblastoma: perineal neoplasm of probable neural origin. (197680)	Eason A.A.... Collins E.J.	1977
18	Granular-cell myoblastoma of the cercum: report of a case. (186241)	Weitzner S.... Nascimento A.G.	1976
19	Granular-cell myoblastoma of the floor of the mouth. (167332)	Caine R.L.... Mesa M.	1975
20	Granular cell myoblastoma arising from the thoracic sympathetic nerve chain. (171368)	Rosenbloom P.M.... Canty T.G.	1975
21	Granular cell tumor (myoblastoma) of the bladder. (4368755)	Mouradian J.A.... Gray G.F.	1974
22	Granular cell myoblastoma of the Larynx. (4370056)	Thawley S.E.... Ogura J.H.	1974
23	Granular cell myoblastoma of the oesophagus. (4361526)	Larsen G.L.... Cline R.E.	1973
24	Granular-cell myoblastoma in parotid gland. (4344178)	Nussbaum M.... Haselkorn A.	1972
25	Granular cell myoblastoma of the neurohypophysis. Report of two cases. (4328296)	Symon L.... Gonz J.C.	1971
26	Granular cell myoblastoma and carcinoma of the larynx. (4329148)	Goldstein A.... Rozycki D.	1971
27	Granular cell myoblastoma (granular cell schwannoma) of the right upper bronchus coexisting with a bronchogenic carcinoma. Report of the first case in the literature. (4327102)	Tamayo J.L.... Rojas M.C.	1971
28	Granular cell myoblastoma of the tongue. (4311994)	Bahuth J.J.... Acquarelli M.J.	1970
29	Granular cell myoblastoma of the canine tongue: case reports. (4297859)	Wyand D.S.... Wolke R.E.	1968
30	Granular-cell myoblastoma of the larynx. (4290655)	Cracovaner A.J.... Opler S.R.	1967
31	Granular cell myoblastoma of the larynx. (4290497)	Sedee G.A.	1967
32	Granular-cell myoblastoma of the anterior uvea. (4378159)	Cunha S.L.... Lobo F.G.	1966
33	Myoblastoma of the tongue. (4286970)	Coyas A.... Pratsika-Ougourloglou C.	1966
34	Granular-cell myoblastoma of the pituitary. (4286074)	Talerman A.... Dawson-Butterworth K.	1966
35	ATRANSPLANTABLE GRANULAR CELL MYOBLASTOMA IN STRAIN C3H MICE. (14342587)	Dunn T.B.... GREEN A.W.	1965
36	BENIGN GRANULAR-CELL MYOBLASTOMA OF THE BRONCHUS. REVIEW OF THE LITERATURE AND REPORT OF A CASE. (14248505)	Campbell D.C.... HOOD R.H.	1964
37	Myoblastoma of the larynx. A report of five cases. (14467644)	LYONS G.D.... BLATT I.M.	1962
38	Myoblastoma of the larynx. (13796324)	Balshi S.F.	1960
39	Granular cell myoblastoma of the breast. (13806636)	BYRNE J.J.... DEAN M.A.	1960
40	Case of granular-cell myoblastoma (organoid type) involving arm, lung, and brain, with twenty years' survival. (13514804)	MEREDITH J.M.... BOSHER L.H.	1958
41	Myoblastoma of the vulva. (13282988)	Hanson S.M.... BEECHAM C.T.	1956
42	Adamantinoma containing tissue resembling granular-cell myoblastoma. (13307333)	Campbell J.A.	1956
43	Benign granular cell myoblastoma of tongue; report of case. (13367952)	Kennedy D.J.	1956
44	Granular cell myoblastoma of the vulva. (13201380)	REICH W.J.... NECHTOW M.J.	1954
45	Congenital myoblastoma of the newborn. (13063924)	Hayward J.R.	1953
46	Granular cell myoblastoma. (13031491)	ROTHCHILD T.P.... CRARY R.H.	1953
47	Granular-cell myoblastoma of labium majus. (13016697)	VALENTINE F.M.... Thomas J.R.	1953
48	Granular cell myoblastoma; report of a case simulating granuloma inguinale. (15426322)	Kern A.B.... COMBES F.C.	1950
49	Granular cell myoblastoma of the anterior rectus sheath. (18114670)	Rogers S.S.	1949
50	Myoblastoma of the bronchus. (18865482)	KRAUS A.R.... WEINBERG J.A.	1948

Genes related to Myoblastoma

Sources:
¹⁷GeneCards, ⁴⁵Novus Biologicals, ³¹LifeSpan BioSciences, Inc.
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Genes related to Myoblastoma:

id	Symbol	Description	Score	Implication
1	SOX8	SRY (sex determining region Y)-box 8	21.96	GeneCards inferred : Disorders (show sections)
2	CHKB	choline kinase beta	17.96	GeneCards inferred : Publications, Disorders (show sections)
3	ENO2	enolase 2 (gamma, neuronal)	14.06	GeneCards inferred : Disorders (show sections)
4	GGCT	gamma-glutamylcyclotransferase	9.96	GeneCards inferred : Disorders (show sections)
5	NPRL3	nitrogen permease regulator-like 3 (S. cerevisiae)	5.96	GeneCards inferred : Disorders (show sections)

Products for genes related to Myoblastoma disease:

id	Company	Proteins	Lysates	Antibodies
1	Novus Biologicals	5	5	5
2	LSBio	-	-	5

Genetic Variations for Myoblastoma

Expression for genes affiliated with Myoblastoma

Sources:
¹BioGPS, ¹⁵Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myoblastoma

Search GEO for disease gene expression data for Myoblastoma.

Pathways for genes affiliated with Myoblastoma

Compounds for genes affiliated with Myoblastoma

Sources:
⁴⁴Novoseek, ²⁴HMDB, ¹¹DrugBank
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Compounds related to Myoblastoma according to GeneCards/GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	spec-t⁴⁴	9.5	ENO2, CHKB
2	malondialdehyde⁴⁴	9.4	ENO2, CHKB
3	bicarbonate⁴⁴	9.4	ENO2, CHKB
4	uric acid⁴⁴ ²⁴	10.3	CHKB, ENO2
5	choline⁴⁴ ¹¹ ²⁴	11.3	ENO2, CHKB
6	catecholamine⁴⁴	9.2	ENO2, CHKB
7	mannitol⁴⁴ ¹¹	10.0	ENO2, CHKB