Myoblastoma disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Myoblastoma

MalaCards based summary: Myoblastoma, also known as benign granular cell tumor, is related to granular cell tumor and malignant granular cell myoblastoma. An important gene associated with Myoblastoma is SOX8 (SRY (sex determining region Y)-box 8). The compounds spec-t and malondialdehyde have been mentioned in the context of this disorder. Affiliated tissues include tongue, breast and trachea.

Aliases & Classifications for Myoblastoma

Sources:
⁹Disease Ontology, ¹¹DISEASES, ⁶¹UMLS, ³⁴MeSH, ³⁹NCIt
See all sources

Myoblastoma, Aliases & Descriptions:

Name: Myoblastoma ⁹ ¹¹ ⁶¹

Benign Granular Cell Tumor ⁹ ⁶¹

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Muscle diseases

External Ids:

Disease Ontology⁹ DOID:5039

MeSH³⁴ D009379

NCIt³⁹ C3252

UMLS⁶¹ C0027043

Related Diseases for Myoblastoma

Sources:
¹⁸GeneCards, ¹⁹GeneDecks
See all sources

Diseases related to Myoblastoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 27)

id	Related Disease	Score
1	granular cell tumor	10.6
2	malignant granular cell myoblastoma	10.6
3	laryngitis	10.3
4	myoma	10.2
5	mediastinal granular cell myoblastoma	10.2
6	cervicitis	10.2
7	congenital epulis	10.1
8	epulis	10.1
9	esophagitis	10.1
10	gingivitis	10.1
11	neurofibroma	10.1
12	thyroiditis	10.1
13	granuloma inguinale	10.0
14	ganglioneuroma	10.0
15	polyhydramnios	10.0
16	cerebritis	10.0
17	chromophobe adenoma	10.0
18	adenocarcinoma	10.0
19	adenoma	10.0
20	cholecystitis	10.0
21	histiocytoma	10.0
22	meningioma	10.0
23	meningitis	10.0
24	papillary adenocarcinoma	10.0
25	rectal neoplasm	10.0
26	sarcoidosis	10.0
27	bronchogenic carcinoma	10.0

Graphical network of the top 20 diseases related to Myoblastoma:

Symptoms for Myoblastoma

Drugs & Therapeutics for Myoblastoma

Sources:
⁴¹NIH Clinical Center, ⁶ClinicalTrials
See all sources

Drug clinical trials:

Search ClinicalTrials for Myoblastoma

Search NIH Clinical Center for Myoblastoma

Genetic Tests for Myoblastoma

Anatomical Context for Myoblastoma

Sources:
³²MalaCards
See all sources

MalaCards organs/tissues related to Myoblastoma:

³²

Tongue, Breast, Trachea, Colon, Lung, Cervix, Pituitary, Eye, Thyroid, Brain, Pancreas, Skin, Uterus, Appendix

Animal Models for Myoblastoma or affiliated genes

Publications for Myoblastoma

Sources:
⁵¹PubMed
See all sources

Articles related to Myoblastoma:

(show top 50) (show all 409)

id	Title	Authors	Year
1	Persistently altered visceral perception after resection of an esophageal granular cell myoblastoma: a therapeutic concept revisited. (13130329)	Canbay A.... RA1nzi M.	2003
2	Granular cell myoblastoma of the cervical esophagus: MR findings. (8896641)	Boncoeur-Martel M.P.... Weinstein G.S.	1996
3	Case report: granular cell myoblastoma of the breast: a rare benign tumour mimicking breast carcinoma. (7489634)	Green D.H.... Clark A.H.	1995
4	Granular cell myoblastoma of the parapharyngeal space. (2832804)	Remsen K.... Vacca M.	1988
5	Granular cell tumor (myoblastoma) of the eyebrow. (3035448)	Pe'er J.... Kopolovic J.	1987
6	Granular cell myoblastoma of the bladder. (2982445)	Fletcher M.S.... Whimster W.F.	1985
7	Contiguous granular cell myoblastoma and squamous cell carcinoma in the oesophagus. (2994248)	Mannion P.... Hasleton P.S.	1985
8	Coexisting granular cell myoblastoma and squamous carcinoma of the bronchus. (6287661)	Hurwitz S.S.... Krut L.H.	1982
9	Granular cell myoblastoma of the head and neck: review of the literature and 10 year experience. (225962)	Noonan J.D.... Stokes T.L.	1979
10	Malignant granular cell tumour (granular cell myoblastoma): a case report. (747994)	Ndinya-Achola J.O.... Kivindu C.M.	1978
11	Granular cell myoblastoma of the vulva. Report of 4 cases. (211789)	Dgani R.... Lancet M.	1978
12	Granular myoblastoma: perineal neoplasm of probable neural origin. (197680)	Eason A.A.... Collins E.J.	1977
13	Giant cell myoblastoma. (4377738)	Schiess A.V.	1974
14	Granular cell myoblastoma of the trachea. (4372978)	Thawley S.E.... Ogura J.H.	1974
15	Bilateral granular cell myoblastoma of the lip: report of case. (4359605)	Slavkin D.M.... Catone G.A.	1973
16	Granular cell myoblastoma of the bladder: report of an additional case. (4355053)	Mizutani S.... Sonoda T.	1973
17	What's your diagnosis? Granular cell myoblastoma. (4346874)	Appel B.N.... Guggenheimer J.	1972
18	Granular cell myoblastoma of the trachea. Response to radiation therapy. (4333188)	Sargent E.N.... George F.W.	1972
19	Granular cell tumor (myoblastoma) of the stomach. A case report with ultrastructural findings and review the literature. (4344382)	Goodman M.D.... Cooper P.H.	1972
20	Seemingly malignant granular cell myoblastoma of the bronchus. (5008122)	Malette W.G.... McClellan J.T.	1972
21	Airway obstruction due to a large laryngeal granular cell myoblastoma. (4326348)	Miglets A.W.... Gregg L.O.	1971
22	Granular cell myoblastoma of the neurohypophysis. Report of two cases. (4328296)	Symon L.... Gonz J.C.	1971
23	Granular-cell myoblastoma of the bronchus. (4327935)	Pollock D.J.... Vernon-Roberts B.	1971
24	Granular cell myoblastoma and carcinoma of the larynx. (4329148)	Goldstein A.... Rozycki D.	1971
25	Endobronchial granular cell myoblastoma. A report of three cases and review of the literature. (4312334)	Ostermiller W.E.... Barker W.L.	1970
26	Granular-cell myoblastoma of the vulva. (4304788)	Radman H.M.... Bhagavan B.S.	1969
27	Granular cell myoblastoma of the breast. (4305173)	Vidyarthi S.C.	1969
28	Granular cell myoblastoma of the bladder: report of a case. (4301412)	Seery W.H.	1968
29	Malignant granular cell myoblastoma. (5602985)	Mackenzie D.H.	1967
30	Granular cell myoblastoma of the vulva. (4294987)	Fliegner J.R.	1967
31	Multiple granular cell myoblastoma. (4289667)	Abel R.R.... Fessenden W.	1966
32	Granular cell myoblastoma of the perianal area: report of a case. (4284069)	Grosberg S.J.... Gellin G.A.	1965
33	GRANULAR CELL MYOBLASTOMA OF THE TONGUE: REPORT OF CASE. (14238016)	FRANCISCO J.V.... REICHMAN L.	1965
34	Granular cell myoblastoma--a misnomer. Electron microscopic and histochemical evidence concerning its Schwann cell derivation and nature (granular cell schwannoma). (13893237)	Fisher E.R.... WECHSLER H.	1962
35	Myoblastoma of the larynx. A report of five cases. (14467644)	LYONS G.D.... BLATT I.M.	1962
36	Exfoliative cytology of a case of bronchial granular cell myoblastoma. (13937258)	NAIB Z.M.... GOLDSTEIN H.G.	1962
37	Granular cell myoblastoma of the bronchus. Report of two cases and review of the literature. (13729494)	NORA P.... HOLMES G.W.	1961
38	Granular cell myoblastoma of the bronchus. (13726678)	MULLANEY P.J.... GODFREY L.B.	1961
39	Benign granular-cell myoblastoma of the bronchus. (13638589)	JONES E.R.... MACARTHUR A.M.	1959
40	Granular-cell myoblastoma of the vulva. (13498077)	WINKELSTEIN L.B.... Friedman S.	1958
41	Granular-cell myoblastoma of the vulva and lower respiratory tract; report of a case. (13419268)	CHIODI N.E.... MCCAUGHAN D.	1957
42	Pseudoepitheliomatous hyperplasia associated with myoblastoma; a diagnostic pitfall. (13169447)	SWERDLOW M.A.... Edwards A.L.	1954
43	Congenital myoblastoma of the newborn. (13063924)	Hayward J.R.	1953
44	Granular-cell myoblastoma; two unusual cases. (13059774)	CRAWFORD E.S.... DE BAKEY M.E.	1953
45	Granular cell myoblastoma of multicentric origin. (13040635)	GUTSTEIN W.H.	1953
46	An early granular-cell myoblastoma confined within a small peripheral myelinated nerve. (13059775)	BANGLE R.	1953
47	Myoblastoma of the floor of the mouth. (13073188)	Bradley J.L.	1953
48	Myoblastoma of the buccal mucosa. (14928130)	FABE S.S.	1952
49	Intracerebral metastatic granular cell myoblastoma. (14804125)	SCHWIDDE J.T.... SWEENEY D.B.	1951
50	Malignant granular cell myoblastoma of the gluteal region. (21000890)	ACKERMAN L.V.... PHELPS C.R.	1946

Genes related to Myoblastoma

Sources:
¹⁸GeneCards, ¹antibodies-online, ⁴⁵Novus Biologicals
See all sources

Genes related to Myoblastoma:

- Elite gene

id	Symbol	Description	Score	Implication
1	SOX8	SRY (sex determining region Y)-box 8	22.45	GeneCards inferred via : Disorders (show sections)
2	CHKB	choline kinase beta	17.45	GeneCards inferred via : Publications (show sections)
3	ENO2	enolase 2 (gamma, neuronal)	12.57	GeneCards inferred via : Disorders (show sections)
4	NPRL3	nitrogen permease regulator-like 3 (S. cerevisiae)	7.45	GeneCards inferred via : Disorders (show sections)

Products for genes related to Myoblastoma disease:

id	Company	Proteins	Lysates	Antibodies	Kits and Assays
1	Antibodies-online	4	-	4	4
2	Novus Biologicals	4	4	4	-

Variations for Myoblastoma

Expression for genes affiliated with Myoblastoma

Sources:
²BioGPS, ¹⁶Gene Expression Omnibus DataSets
See all sources

Expression patterns in normal tissues for genes affiliated with Myoblastoma

Search GEO for disease gene expression data for Myoblastoma.

Pathways for genes affiliated with Myoblastoma

Compounds for genes affiliated with Myoblastoma

Sources:
⁴⁴Novoseek, ²⁵HMDB, ¹²DrugBank, ⁵⁰PharmGKB, ²⁹IUPHAR
See all sources

Compounds related to Myoblastoma according to GeneCards/GeneDecks:

(show all 17)

id	Compound	Score	Top Affiliating Genes
1	spec-t⁴⁴	9.3	ENO2, CHKB
2	malondialdehyde⁴⁴	9.3	ENO2, CHKB
3	bicarbonate⁴⁴	9.3	ENO2, CHKB
4	uric acid⁴⁴ ²⁵	10.3	ENO2, CHKB
5	catecholamine⁴⁴	9.3	CHKB, ENO2
6	mannitol⁴⁴ ¹²	10.3	ENO2, CHKB
7	choline⁴⁴ ²⁵ ¹²	11.3	ENO2, CHKB
8	pyruvate⁴⁴	9.3	ENO2, CHKB
9	methotrexate⁵⁰ ⁴⁴ ¹²	11.2	CHKB, ENO2
10	norepinephrine⁴⁴ ²⁵ ¹²	11.2	ENO2, CHKB
11	glycogen⁴⁴ ²⁵	10.2	ENO2, CHKB
12	potassium⁴⁴ ²⁵ ¹²	11.1	ENO2, CHKB
13	paraffin⁴⁴	9.1	CHKB, ENO2
14	glutamine⁴⁴	9.0	ENO2, CHKB
15	superoxide⁴⁴ ²⁵	10.0	ENO2, CHKB
16	lactate⁴⁴	8.9	ENO2, CHKB
17	dopamine⁴⁴ ²⁹ ²⁵ ¹²	11.7	ENO2, CHKB

GO Terms for genes affiliated with Myoblastoma

Products for genes affiliated with Myoblastoma

Antibodies
Proteins
Lysates

Antibodies
Proteins
Kits and Assays

Sources for Myoblastoma

¹antibodies-online

²BioGPS

³BitterDB

⁴CDC

⁵Cell Signaling Technology

⁶ClinicalTrials

⁷Clinvar

⁸dbSNP

⁹Disease Ontology

¹⁰diseasecard

¹¹DISEASES

¹²DrugBank

¹³EMD Millipore

¹⁴ExPASy

¹⁵FMA

¹⁶Gene Expression Omnibus DataSets

¹⁷Gene Ontology

¹⁸GeneCards

¹⁹GeneDecks

²⁰GeneReviews

²¹GeneTests

²²Genetics Home Reference

²³GTR

²⁴HGMD

²⁵HMDB

²⁶ICD10

²⁷ICD10 via Orphanet

²⁸ICD9CM

²⁹IUPHAR

³⁰KEGG

³¹LifeMap Discovery®

³²MalaCards

³³MedlinePlus

³⁴MeSH

³⁵MESH via Orphanet

³⁶MGI

³⁷NCBI BioSystems Database

³⁸NCBI Bookshelf

³⁹NCIt

⁴⁰NDF-RT

⁴¹NIH Clinical Center

⁴²NIH Rare Diseases

⁴³NINDS

⁴⁴Novoseek

⁴⁵Novus Biologicals

⁴⁶OMIM

⁴⁷OMIM via Orphanet

⁴⁸Orphanet

⁴⁹PathCards

⁵⁰PharmGKB

⁵¹PubMed

⁵²QIAGEN

⁵³R&D Systems

⁵⁴Reactome

⁵⁵SinoBiological

⁵⁶SNOMED-CT

⁵⁷SNOMED-CT via Orphanet

⁵⁸The Human Phenotype Ontology

⁵⁹Thomson Reuters

⁶⁰Tocris Bioscience

⁶¹UMLS

⁶²UMLS via Orphanet

⁶³UniProtKB/Swiss-Prot

⁶⁴Wikipedia

MCID: MYB001 MIFTS: 36	Myoblastoma malady Muscle diseases, Cancer diseases categories
4 genes, 14 tissues, 27 related diseases, clinical trials Download this MalaCard Expand all tables

Myoblastoma malady