MCID: MYC007
MIFTS: 92

Myocardial Infarction malady

Genetic diseases (common), Cardiovascular diseases categories
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Summaries for Myocardial Infarction

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Sources:
34MedlinePlus, 65Wikipedia, 47OMIM, 33MalaCards
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Fully expand this MalaCard
MedlinePlus:34 Each year over a million people in the u.s. have a heart attack. about half of them die. many people have permanent heart damage or die because they don't get help immediately. it's important to know the symptoms of a heart attack and call 9-1-1 if someone is having them. those symptoms include chest discomfort - pressure, squeezing, or pain shortness of breath discomfort in the upper body - arms, shoulder, neck, back nausea, vomiting, dizziness, lightheadedness, sweating these symptoms can sometimes be different in women. what exactly is a heart attack? most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. often this leads to an irregular heartbeat - called an arrhythmia - that causes a severe decrease in the pumping function of the heart. a blockage that is not treated within a few hours causes the affected heart muscle to die. nih: national heart, lung, and blood institute

MalaCards: Myocardial Infarction, also known as myocardial infarctions, is related to acute myocardial infarction and coronary artery disease. An important gene associated with Myocardial Infarction is MIAT (myocardial infarction associated transcript (non-protein coding)), and among its related pathways are Keap1-Nrf2 Pathway and OX40 Pathway. The drugs diltiazem and verapamil and the compounds z-dqmd-fmk and pravastatin have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and endothelial, and related mouse phenotypes are cardiovascular system and immune system.

Wikipedia:65 Myocardial infarction (from Latin: Infarctus myocardii, MI) or acute myocardial infarction (AMI) is the... more...

Description from OMIM:47 608446

Aliases & Classifications for Myocardial Infarction

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Sources:
8Disease Ontology, 22GTR, 47OMIM, 10DISEASES, 45Novoseek, 34MedlinePlus, 31LifeMap Discovery™, 62UMLS, 58SNOMED-CT, 40NCIt, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

myocardial infarction 8 47 10 45 31 62
myocardial infarctions 8 22
heart attack 8 34
mi - myocardial infarction 8
myocardial infarction nos 8
myocardial infarct 8
attack - heart 8


External Ids:

Disease Ontology8 DOID:5844
NCIt40 C27996
MeSH35 D009203

Related Diseases for Myocardial Infarction

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17GeneCards, 18GeneDecks
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Diseases in the Myocardial Infarction family:

Posterior Myocardial Infarction Acute Myocardial Infarction
Myocardial Infarction, Susceptibility to, 1 Myocardial Infarction 2

Diseases related to Myocardial Infarction via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 485)
idRelated DiseaseScoreTop Affiliating Genes
1acute myocardial infarction32.8CKM, OLR1, ACE
2coronary artery disease31.7ACE, ITGB3, OLR1
3hypertension31.5PPIG, PTGIS, ACE, OLR1
4atherosclerosis31.5PPIG, PTGIS, CIITA, PROCR, MEF2A, ACE
5ischemia31.4PPIG, PTGIS, CIITA, CASP1, OLR1
6systemic lupus erythematosus30.9TNFSF4, CIITA, PROCR, LTA
7vascular disease30.9PTGIS, MEF2A, ACE, ITGB3, OLR1
8psoriasis30.7CIITA, CASP1, GZMB, LTA
9arthritis30.7LTA, GZMB, CASP1, CIITA
10rheumatoid arthritis30.7LTA, GZMB, CASP1, ITGB3, CIITA
11cerebrovascular disease30.7MEF2A, PROCR, CIITA, PTGIS, PPIG, ACE
12leukemia30.6PPIG, TNFSF4, ITGB3, CASP1, CKM, GZMB
13influenza30.6PPIG, CIITA, CASP1, GZMB, LTA
14septic shock30.6LTA, CASP1, CIITA
15lung cancer30.5PPIG, PTGIS, CIITA, PROCR, CASP1, GZMB
16sarcoidosis30.4ACE, GZMB, LTA
17diabetic retinopathy30.4ACE, ITGB3, CASP1
18systemic scleroderma30.4CIITA, ACE, CASP1
19type 1 diabetes mellitus30.4CIITA, ACE, LTA
20congenital heart disease30.2PPIG, ACE, OLR1
21melanoma30.2PPIG, CIITA, ITGB3, CASP1, GZMB
22prostate cancer30.1PPIG, ESR1, ITGB3, GZMB, LTA
23adenocarcinoma30.0PPIG, PTGIS, ESR1, CASP1, GCLM
24inferior myocardial infarction11.3
25cardiogenic shock11.1
26artery disease11.0
27cardiac rupture11.0
28endotheliitis11.0
29posterior myocardial infarction11.0
30aneurysm11.0
31coronary thrombosis11.0
32angina pectoris10.9
33silent myocardial infarction10.9
34right bundle branch block10.9
35myocardial infarction 210.9
36myocarditis10.9
37anteroseptal myocardial infarction10.8
38diabetes mellitus10.8
39coronary artery aneurysm10.8
40dextrocardia10.7
41coronary stenosis10.7
42spontaneous coronary artery dissection10.7
43coronary aneurysm10.7
44blindness10.7
45lateral myocardial infarction10.7
46acute myocarditis10.7
47ventricular septal defect10.7
48obesity10.7
49atrioventricular block10.7
50congestive heart failure10.6

Graphical network of the top 20 diseases related to Myocardial Infarction:



Diseases related to myocardial infarction

Symptoms for Myocardial Infarction

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47OMIM
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Clinical features from OMIM:

608446

Drugs & Therapeutics for Myocardial Infarction

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 31LifeMap Discovery™, 62UMLS, 41NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Myocardial Infarction

Search NIH Clinical Center for Myocardial Infarction

Inferred drug relations via UMLS62/NDF-RT41:

Show with subtypes

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Myocardial Infarction cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Myocardial Infarction:
ADRCs, adipose-derived regenerative cells for treatment of cardiovascular disease
AMI MultiStem
AMR-001, bone marrow-derived CD34+ cells for myocardial infarction
Autologous bone marrow-derived mononuclear cells for myocardial infarction
Bone marrow or peripheral blood-derived stem cells for treatment of myocardial ischemia
Bone marrow-derived adult mononuclear cells for heart diseases
Bone marrow-derived CD133+ vs. mononuclear cells for treatment of myocardial infarction
Bone marrow-derived mesenchymal stem cells for treatment of myocardial ischemia
Bone marrow-derived mononuclear cells for acute myocardial infarction
Bone marrow-derived mononuclear cells for myocardial infarction
Bone marrow-derived mononuclear cells for myocardial infarction
Bone marrow-derived mononuclear cells for myocardial infarction
Bone marrow-derived mononuclear cells for treatment of myocardial infarction
Bone marrow-derived progenitor cells for myocardial infarction
Bone marrow-derived stem cells for treatment of ischemic cardiomyopathy
Cardiosphere-derived autologous stem cells for reverse ventricular dysfunction
Cardiosphere-derived cells for the treatment of myocardial infarction
CD133+ bone marrow-derived stem cells in conjuction with coronary artery bypass grafting
Combination therapy of mononuclear cells with laser for coronary disease
Early endothelial progenitor cells for acute myocardial infarction
Embryonic stem cell-derived cardiomyocyte transplantation for myocardial infarction
Embryonic stem cell-derived cardiomyocytes for treatment of myocardial infarction
Enriched bone marrow-derived progenitor cells for heart diseases
Hearticellgram
Hydrogels with cardiomyocytes for myocardial repair
Mesenchymal precursor cells for cardiovascular diseases
Mesendo, stem cell combination for treatment of cardiovascular diseases
MyoCell
Prochymal
Sca-1-positive cardiac progenitor cells for treatment of myocardial infarction
Stem cell therapy for treatment of acute myocardial infarction
StempeucelAMI
Umbilical cord blood-derived CD133 positive cells for treatment of myocardial infarction
Embryonic/Adult Cultured Cells Related to Myocardial Infarction:
Adipose-derived stem and regenerative cell, PMIDs: 21082397, 22281257
Bone marrow-derived adherent progenitor cells (MultiStem), PMIDs: 22004910, 22052917
Bone marrow-derived autologous CD34+cells (AMR-001), PMID: 21167340
Bone marrow-derived mononuclear cells, PMID: 19002124
Bone marrow-derived mononuclear cells
Peripheral blood-derived hematopoietic stem cells (family)
Bone marrow-derived mononuclear cells, PMIDs: 22137069, 19699857, 20445812, 20524773
Bone marrow-derived CD133+ hematopoietic stem cells
Bone marrow-derived mononuclear cells (family)
Bone marrow-derived mesenchymal stem cells (family)
Bone marrow-derived mononuclear cells (family)
Bone marrow-derived mononuclear cells, PMID: 22834565
Bone marrow-derived mononuclear cells, PMID: 22834565
Bone marrow-derived mononuclear cells (family), PMIDs: 22192151, 21414223
Bone marrow-derived mononuclear cells (family), PMIDs: 16889856, 16382259
Bone marrow-derived mesenchymal stem cells, PMIDs: 16889856, 16382259
Bone marrow-derived mononuclear cells
Bone marrow-derived progenitor cells, PMIDs: 20448133, 16159812, 18293890
Bone marrow-derived mesenchymal stem cells , PMIDs: 21392602, 22940024
Bone marrow-derived mononuclear cells (family), PMIDs: 21392602, 22940024
Porcine bone marrow-derived mesenchymal stem cells, PMIDs: 21392602, 22940024
Cardiosphere-derived cells, PMID: 22336189
Cardiosphere-derived cells, PMIDs: 17283259, 22336189
Bone marrow-derived CD133+ cells, PMID: 17320570
Bone marrow-derived mononuclear cells (family)
eNOS-transfected endothelial progenitor cells, PMIDs: 21362705, 22239631
Peripheral blood-derived endothelial progenitor cells, PMIDs: 21362705, 22239631
Cardiomyocyte-like cells, PMID: 17980256
Cardiomyocyte-like cells, PMID: 22040108
Bone marrow-derived progenitor cells, PMIDs: 23362308, 22936827, 18794392, 16990384, 16990385, 22651868
Bone marrow-derived mesenchymal stem cells (family)
Neonatal rat ventricular cardiomyocytes , PMID: 21783246
Cardiomyocyte-like cells, PMID: 21783246
Mesenchymal Precursor Cells (STRO-3 selected), PMIDs: 20850099, 21155976
Bone marrow-derived mononuclear cells, PMIDs: 21323410, 20631864
Bone marrow-derived mesenchymal stem cells, PMIDs: 21323410, 20631864
Skeletal myoblasts (MyoCell, PMIDs: 19051139, 15615560, 16446778
Cardiac progenitor cells (Sca1+), PMID: 21980409
Bone marrow-derived mononuclear cells (family)
Bone marrow-derived CD34+/CXCR4+ cells
Bone marrow-derived mesenchymal stem cells (Stempeucel, PMID: 18720444
Umbilical cord blood-derived CD133+ cells, PMID: 16195418

Genetic Tests for Myocardial Infarction

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22GTR
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Genetic tests related to Myocardial Infarction:

id Genetic test Affiliating Genes
1 Myocardial Infarction22

Anatomical Context for Myocardial Infarction

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31LifeMap Discovery™, 33MalaCards
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MalaCards organs/tissues related to Myocardial Infarction:

33
Heart, Bone, Endothelial, Brain, Lung, Monocytes, Testes, Bone marrow, Kidney, Prostate, Whole blood, Thyroid, Skeletal muscle, Liver, Pituitary, Myeloid, Skin, Spinal cord, T cells, Atrioventricular node, Uterus, Small intestine, Spleen, Cardiac myocytes, Pons

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Myocardial Infarction:
id TissueAnatomical CompartmentCell Relevance
1 BoneBone MarrowBone Marrow Stromal Cells Potential therapeutic candidate
2 LimbPelvic GirdleBone Marrow Stromal Cells Potential therapeutic candidate
3 HeartMyocardiumCardiomyocytes Potential therapeutic candidate, affected by disease

Animal Models for Myocardial Infarction or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Myocardial Infarction:

37 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538510.6TNFSF4, PTGIS, ESR1, MEF2A, ACE, ITGB3
2MP:000538710.5PROCR, ESR1, CIITA, TNFSF4, ACE, ITGB3
3MP:000537610.5LTA, TNFSF4, PTGIS, CIITA, ESR1, PROCR
4MP:001076810.5ACE, MEF2A, PROCR, ESR1, LRP8, ITGB3
5MP:000539710.5TNFSF4, CIITA, ESR1, PROCR, ACE, ITGB3
6MP:000538410.5LRP8, ESR1, ACE, ITGB3, CASP1, CKM
7MP:000536910.5ESR1, MEF2A, ITGB3, OLR1, GJA4, CKM
8MP:000200610.4ESR1, ACE, ITGB3, CASP1, GZMB
9MP:000287310.4GCLC, OLR1, ITGB3, PROCR, CIITA, LRP8
10MP:000537810.3LRP8, ESR1, PROCR, ACE, ITGB3, CKM
11MP:000537010.1ESR1, ACE, ITGB3, GCLC, LTA

Publications for Myocardial Infarction

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52PubMed
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Articles related to Myocardial Infarction:

(show top 50)    (show all 6111)
idTitleAuthorsYear
1
Recurrent Myocardial Infarction After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction. (24188893)
2014
2
Negative Impact of I^-Arrestin-1 on Post-Myocardial Infarction Heart Failure via Cardiac and Adrenal-Dependent Neurohormonal Mechanisms. (24218435)
2014
3
The effects of aging on apoptosis following myocardial infarction. (24279384)
2013
4
Acute Myocardial Infarction Caused by Infective Endocarditis. (24316084)
2013
5
The Relationship of Acute Myocardial Infarction With or Without ST-Segment Elevation and Viscosity. (23742945)
2013
6
Endoscopy after acute myocardial infarction: an evaluation of safety. (24096947)
2013
7
Comparison of cancer risk associated with low-dose ionizing radiation from cardiac imaging and therapeutic procedures after acute myocardial infarction in women versus men. (23972348)
2013
8
Validity of the GRACE score for 6-month death or reinfarction after presentation with acute myocardial infarction in patients 80 years of age and older. (23965947)
2013
9
Cardiovascular outcomes using intra-aortic balloon pump in high-risk acute myocardial infarction with or without cardiogenic shock: a meta-analysis. (21335478)
2012
10
Lack of association between IL-1 and IL-6 gene polymorphisms and myocardial infarction in Turkish population. (21199393)
2011
11
Diagnostic performance of high-sensitivity troponin T, myeloperoxidase, and pregnancy-associated plasma protein A assays for triage of patients with acute myocardial infarction. (21779191)
2011
12
Myocardial infarction and cerebrovascular accident in patients with retinal vein occlusion. (21402990)
2011
13
Hepatic and renal failure after anterior myocardial infarction induced apical ventricular septal defect. (21274286)
2010
14
Oxidative stress and platelet activation: markers of myocardial infarction in type 2 diabetes mellitus. (19759031)
2010
15
Appraisal of the prognosis in patients with acute myocardial infarction treated with primary percutaneous coronary intervention. (19568720)
2009
16
The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor mediated ex vivo platelet function in acute myocardial infarction. (19637097)
2009
17
Acute inferior myocardial infarction due to cannabis smoking in a young man. (19436220)
2009
18
Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients. (19540141)
2009
19
Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels. (19404549)
2009
20
Plasma adiponectin and resistin levels as predictors of mortality in patients with acute myocardial infarction: data from infarction prognosis study registry. (18997620)
2009
21
Intensive insulin therapy in non-diabetic patients with myocardial infarction and hyperglycemia. INSUCOR study]. (18482525)
2008
22
Quantitative relationship between resting heart rate reduction and magnitude of clinical benefits in post-myocardial infarction: a meta-regression of randomized clinical trials. (17981830)
2007
23
Glomerular filtration rate on admission independently predicts short-term in-hospital mortality after acute myocardial infarction. (16926535)
2006
24
Incidental myocardial infarction in Ehlers-Danlos syndrome type IV? (15813560)
2005
25
No replication of association between estrogen receptor alpha gene polymorphisms and susceptibility to myocardial infarction in a large sample of patients of European descent. (16203927)
2005
26
The risk for myocardial infarction with cyclooxygenase-2 inhibitors. (16230737)
2005
27
Do statins influence the prognostic impact of non-sustained ventricular tachycardia after ST-elevation myocardial infarction? (15728647)
2005
28
Serum levels of endostatin, vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in patients with acute myocardial infarction undergoing early reperfusion therapy. (14965340)
2004
29
Plasma adiponectin levels and risk of myocardial infarction in men. (15082700)
2004
30
Interheart: nine risk factors predict nine out of ten myocardial infarctions]. (15646744)
2004
31
Mitochondrial 5178A/C genotype is associated with acute myocardial infarction. (12520145)
2003
32
Essential thrombocytosis causing a massive myocardial infarction. (12826291)
2003
33
Myoglobin, creatine kinase MB isoforms and creatine kinase MB mass in early diagnosis of myocardial infarction in patients with acute chest pain. (12499000)
2002
34
Annexin V does not represent a diagnostic alternative to myoglobin for early detection of myocardial infarction. (12389712)
2002
35
Acute myocardial infarction: a rare complication of protein C deficiency. (11294179)
2001
36
Soluble P-selectin and the success of thrombolysis in acute myocardial infarction. (11461745)
2001
37
Plasma levels of neuropeptide Y i patients with current myocardial infarction]. (11505745)
2001
38
Angiotensin II type-I receptor and ACE polymorphisms and risk of myocardial infarction in men and women. (11122322)
2000
39
Survival outcomes 1 year after reperfusion therapy with either alteplase or reteplase for acute myocardial infarction: results from the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO) III Trial. (11023929)
2000
40
Intracranial hemorrhage rates and effect of immediate beta-blocker use in patients with acute myocardial infarction treated with tissue plasminogen activator. Participants in the National Registry of Myocardial Infarction-2. (11078295)
2000
41
Elevated plasma levels of interleukin-1 receptor antagonist and interleukin-10 in patients with acute myocardial infarction. (9085939)
1997
42
Effects of ramipril and spironolactone on ventricular remodeling after acute myocardial infarction: randomized and double-blind study]. (9515282)
1997
43
Indicators of lipoprotein metabolism in normolipemic men after myocardial infarct]. (7489572)
1995
44
Brazilian study with alteplase in acute myocardial infarction--EBRALT]. (8554497)
1995
45
Plasma neuropeptide Y levels in the acute and early convalescent phase after myocardial infarction. (8154414)
1994
46
Evidence of a partial escape of renin-angiotensin-aldosterone blockade in patients with acute myocardial infarction treated with ACE inhibitors. (8429112)
1993
47
Exercise-induced precordial ST-segment depression in prior inferior myocardial infarction with single-vessel disease; with special reference to its mechanisms and distinction from multi-vessel disease. (3343075)
1988
48
The beriberi analogy to myocardial infarction. (6341793)
1983
49
Anatomic, clinical, and therapeutic features of acute cardiac rupture. Successful surgical management fourteen hours after myocardial infarction. (661371)
1978
50
Contribution to the enzymic diagnosis of acute myocarditis, myocardial infarction and cardiogenic shock. (5384064)
1969

Variations for Myocardial Infarction

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1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Myocardial Infarction:

1
id Gene Name Type Significance SNP ID Assembly Location
1ACENM_000789.3: c.2306-117_2306-116insAF118569.1: g.14094_14382insertionBenign, Pathogenic, risk factorrs4340GRCh37Chr 17, 61565892: 61565893

Expression for genes affiliated with Myocardial Infarction

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myocardial Infarction

Search GEO for disease gene expression data for Myocardial Infarction.

Pathways for genes affiliated with Myocardial Infarction

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Sources:
50PathCards, 38NCBI BioSystems Database, 53QIAGEN, 55Reactome, 30KEGG, 57SinoBiological, 54R&D Systems
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Pathways related to Myocardial Infarction according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.5GCLC, GCLM
210.5LTA, TNFSF4
3
Show member pathways
creatine-phosphate biosynthesis38
glycine degradation (creatine biosynthesis)38
putrescine biosynthesis III38
spermidine biosynthesis I38
tryptophan degradation via kynurenine38
spermine biosynthesis38
urea cycle38
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I38
tyrosine degradation I38
L-carnitine biosynthesis38
methylthiopropionate biosynthesis38
2-oxoglutarate decarboxylation to succinyl-CoA38
S-methyl-5-thioadenosine degradation II38
10.4GCLM, GCLC, CKM
4
Show member pathways
10.4LTA, CASP1, TNFSF4
5
Show member pathways
10.4TNFSF4, CASP1, LTA
6
Show member pathways
Apoptosis Modulation and Signaling38
Apoptosis38
10.4LTA, GZMB, CASP1
7
Show member pathways
10.4LTA, GZMB, CASP1, ITGB3

Compounds for genes affiliated with Myocardial Infarction

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Sources:
61Tocris Bioscience, 29IUPHAR, 45Novoseek, 51PharmGKB, 24HMDB, 11DrugBank
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Compounds related to Myocardial Infarction according to GeneCards/GeneDecks:

(show all 48)
idCompoundScoreTop Affiliating Genes
1z-dqmd-fmk61 2911.8PPIG, CASP1, GZMB
2pravastatin45 51 29 24 1114.8PPIG, ACE, CASP1, OLR1
3az 104178086110.8PPIG, CASP1, GZMB
4z-devd-fmk61 2911.8PPIG, CASP1, GZMB
5clopidogrel45 51 24 1113.8PPIG, ACE, ITGB3
6z-vad-fmk45 6111.8GZMB, CASP1, PPIG
7diethylmaleate4510.8GCLM, GCLC
84-hydroxynonenal45 2411.8CASP1, GCLC, GCLM
9cholesterol45 29 24 1113.8LRP8, PTGIS, CIITA, ACE, OLR1, LTA
10endotoxin4510.8LTA, CASP1, PROCR, CIITA
11aspirin45 51 29 2413.8CASP1, ITGB3, ACE, PTGIS
12fluvastatin45 51 29 1113.8CASP1, ACE, PPIG
13cisplatin45 51 61 1113.8PPIG, ESR1, CASP1, GZMB, GCLC, GCLM
14sele4510.8ACE, ITGB3
15oxygen45 2411.8PTGIS, CIITA, CASP1, OLR1, CKM, GZMB
16steroid4510.8PPIG, CIITA, ESR1, MEF2A, ITGB3, GZMB
17cyclosporin a45 29 6112.8PPIG, CIITA, MEF2A, CASP1, GZMB, LTA
18vegf4510.8ESR1, PROCR, ITGB3, CASP1, GZMB, LTA
19cysteine4510.8CIITA, ITGB3, CASP1, OLR1, CKM, GZMB
20toxin-14510.8CIITA, LTA
21glucose4510.8ACE, MEF2A, CIITA, PTGIS, ITGB3, CASP1
22atorvastatin45 51 29 24 1114.8OLR1, ACE, PPIG
23lipid4510.8PROCR, CIITA, PTGIS, LRP8, ACE, ITGB3
24serine4510.8CIITA, PROCR, MEF2A, ITGB3, CASP1, GJA4
25retinoic acid45 2411.8ESR1, MEF2A, CASP1, GJA4, GZMB, LTA
26actinomycin d4510.8CIITA, ESR1, CASP1, LTA
27nitric oxide45 24 1112.8LTA, LRP8, PTGIS, CIITA, PROCR, ACE
28calcium45 51 24 1113.7CIITA, PROCR, MEF2A, ACE, ITGB3, CASP1
29dexamethasone45 51 29 1113.7PPIG, CIITA, CASP1, GZMB, LTA
30tyrosine4510.7LRP8, PTGIS, CIITA, ITGB3, CASP1, GZMB
31L-Cysteine24 1111.7GCLC, GCLM
32pge24510.7LTA, CASP1, CIITA, PTGIS
33simvastatin45 51 61 29 24 1115.7OLR1, CIITA, PPIG
34lactate4510.7CASP1, CKM, GZMB, LTA
35glutamate4510.7MEF2A, CASP1, CKM, GZMB, LTA
36superoxide45 2411.7PTGIS, CASP1, OLR1, GZMB
37chromium4510.7CASP1, GZMB
38mannose4510.7LTA, OLR1, CIITA
39estrogen4510.6ESR1, ITGB3, CASP1, GZMB, LTA
40creatinine4510.6CKM, CASP1, ACE, MEF2A
41minocycline45 1111.6CIITA, CASP1
425-aza-2deoxycytidine4510.6CASP1, ESR1, CIITA
43atp45 2911.5ITGB3, CASP1, OLR1, CKM, GZMB
44ecori4510.5LTA, CIITA
45buthionine sulfoximine4510.5GCLM, GCLC
46beta-naphthoflavone45 1111.4GCLC, PPIG
47phosphatidylserine45 29 1112.3ITGB3, CASP1, GZMB
48cycloheximide4510.1LTA, CASP1, ESR1, CIITA

GO Terms for genes affiliated with Myocardial Infarction

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16Gene Ontology
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Cellular components related to Myocardial Infarction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor complexGO:04323510.5OLR1, ITGB3, LRP8
2glutamate-cysteine ligase complexGO:01710910.2GCLM, GCLC

Biological processes related to Myocardial Infarction according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1regulation of mitochondrial depolarizationGO:05190010.7GCLM, GCLC
2response to nitrosative stressGO:05140910.7GCLM, GCLC
3cysteine metabolic processGO:00653410.7GCLC, GCLM
4glutamate metabolic processGO:00653610.7GCLM, GCLC
5proteolysisGO:00650810.7GZMB, OLR1, CASP1, LRP8
6regulation of blood vessel sizeGO:05088010.7GCLM, GCLC
7glutathione biosynthetic processGO:00675010.6GCLM, GCLC
8xenobiotic metabolic processGO:00680510.6PTGIS, GCLC, GCLM
9apoptotic mitochondrial changesGO:00863710.6GCLM, GCLC
10blood coagulationGO:00759610.5OLR1, ITGB3, PROCR, LRP8
11cellular nitrogen compound metabolic processGO:03464110.4GCLM, GCLC, CKM
12signal transductionGO:00716510.4LRP8, TNFSF4, ESR1, CASP1, LTA
13sulfur amino acid metabolic processGO:00009610.4GCLM, GCLC
14glutathione derivative biosynthetic processGO:190168710.2GCLM, GCLC

Molecular functions related to Myocardial Infarction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1glutamate-cysteine ligase activityGO:00435710.5GCLM, GCLC
2tumor necrosis factor receptor bindingGO:00516410.5TNFSF4, LTA
3protein bindingGO:00551510.2PPIG, LRP8, PTGIS, CIITA, ESR1, PROCR
4activating transcription factor bindingGO:03361310.1MEF2A, CIITA

Products for genes affiliated with Myocardial Infarction

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Myocardial Infarction

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet