MCID: MYC007
MIFTS: 93

Myocardial Infarction malady

Genetic diseases (common), Cardiovascular diseases categories
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Summaries for Myocardial Infarction

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MedlinePlus:33 Each year over a million people in the u.s. have a heart attack. about half of them die. many people have permanent heart damage or die because they don't get help immediately. it's important to know the symptoms of a heart attack and call 9-1-1 if someone is having them. those symptoms include chest discomfort - pressure, squeezing, or pain shortness of breath discomfort in the upper body - arms, shoulder, neck, back nausea, vomiting, dizziness, lightheadedness, sweating these symptoms can sometimes be different in women. what exactly is a heart attack? most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. often this leads to an irregular heartbeat - called an arrhythmia - that causes a severe decrease in the pumping function of the heart. a blockage that is not treated within a few hours causes the affected heart muscle to die. nih: national heart, lung, and blood institute

MalaCards based summary: Myocardial Infarction, also known as myocardial infarctions, is related to acute myocardial infarction and atherosclerosis. An important gene associated with Myocardial Infarction is MIAT (myocardial infarction associated transcript (non-protein coding)), and among its related pathways are Keap1-Nrf2 Pathway and OX40 Pathway. The drugs diltiazem and verapamil and the compounds oxygen and lipid have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and endothelial, and related mouse phenotypes are homeostasis/metabolism and cardiovascular system.

Wikipedia:65 Myocardial infarction (MI; Latin: infarctus myocardii) or acute myocardial infarction (AMI) is the... more...

Description from OMIM:46 608446

Aliases & Classifications for Myocardial Infarction

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Myocardial Infarction, Aliases & Descriptions:

Name: Myocardial Infarction 30 8 46 10 44 62
Myocardial Infarctions 8 22 62
Mi - Myocardial Infarction 8 62
Heart Attack 8 33
 
Myocardial Infarction Nos 8
Myocardial Infarct 8
Attack - Heart 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)
Anatomical: Cardiovascular diseases


External Ids:

Disease Ontology8 DOID:5844
MeSH34 D009203
NCIt39 C27996

Related Diseases for Myocardial Infarction

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Diseases in the Myocardial Infarction family:

Acute Myocardial Infarction Posterior Myocardial Infarction
Myocardial Infarction, Susceptibility to, 1 Myocardial Infarction 2

Diseases related to Myocardial Infarction via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 482)
idRelated DiseaseScoreTop Affiliating Genes
1acute myocardial infarction33.4CKM, OLR1, ACE
2atherosclerosis32.2GJA4, PTGIS, PROCR, MEF2A, ACE, ITGB3
3hypertension32.0PTGIS, ACE, OLR1
4vascular disease31.5ITGB3, OLR1, PTGIS, MEF2A, ACE
5coronary artery anomaly31.5ACE, OLR1, ITGB3
6cerebrovascular disease31.4OLR1, CASP1, ITGB3, ACE, MEF2A, LTA
7influenza31.1CASP1, GZMB, LTA
8leukemia31.1LTA, GZMB, CKM, CASP1, ITGB3, TNFSF4
9sarcoidosis31.1LTA, ACE, GZMB
10diabetic retinopathy31.1ACE, ITGB3, CASP1
11congenital heart disease30.8CASP1, CKM, ACE, MEF2A
12inferior myocardial infarction11.3
13cardiogenic shock11.1
14artery disease11.1
15cardiac rupture11.0
16endotheliitis11.0
17posterior myocardial infarction11.0
18aneurysm11.0
19coronary thrombosis11.0
20angina pectoris10.9
21silent myocardial infarction10.9
22right bundle branch block10.9
23myocardial infarction 210.9
24myocarditis10.9
25diabetes mellitus10.9
26anteroseptal myocardial infarction10.8
27ischemia10.8
28coronary artery aneurysm10.8
29dextrocardia10.8
30spontaneous coronary artery dissection10.7
31coronary aneurysm10.7
32acute myocarditis10.7
33coronary stenosis10.7
34blindness10.7
35lateral myocardial infarction10.7
36ventricular septal defect10.7
37obesity10.7
38congestive heart failure10.7
39atrioventricular block10.7
40subendocardial myocardial infarction10.7
41wolff-parkinson-white syndrome10.6
42left ventricular outflow tract obstruction10.6
43ischemic heart disease10.6
44septal myocardial infarction10.6
45pericarditis10.6
46hemopericardium10.6
47myositis10.6CASP1, GZMB, CKM
48ulcerative colitis10.6PROCR, CASP1, GZMB, LTA
49apical myocardial infarction10.6
50hyperglycemia10.6

Graphical network of the top 20 diseases related to Myocardial Infarction:



Diseases related to myocardial infarction

Symptoms for Myocardial Infarction

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Clinical features from OMIM:

608446

Drugs & Therapeutics for Myocardial Infarction

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Drug clinical trials:

Search ClinicalTrials for Myocardial Infarction

Search NIH Clinical Center for Myocardial Infarction

Inferred drug relations via UMLS62/NDF-RT40:

Show with subtypes

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Myocardial Infarction cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Myocardial Infarction:
ADRCs, adipose-derived regenerative cells for treatment of cardiovascular disease
AMI MultiStem
AMR-001, bone marrow-derived CD34+ cells for myocardial infarction
Autologous bone marrow-derived mononuclear cells for myocardial infarction
Bone marrow or peripheral blood-derived stem cells for treatment of myocardial ischemia
Bone marrow-derived adult mononuclear cells for heart diseases
Bone marrow-derived CD133+ vs. mononuclear cells for treatment of myocardial infarction
Bone marrow-derived mesenchymal stem cells for treatment of myocardial ischemia
Bone marrow-derived mononuclear cells for acute myocardial infarction
Bone marrow-derived mononuclear cells for myocardial infarction
Bone marrow-derived mononuclear cells for myocardial infarction
Bone marrow-derived mononuclear cells for myocardial infarction
Bone marrow-derived mononuclear cells for treatment of myocardial infarction
Bone marrow-derived progenitor cells for myocardial infarction
Bone marrow-derived stem cells for treatment of ischemic cardiomyopathy
Cardiosphere-derived autologous stem cells for reverse ventricular dysfunction
Cardiosphere-derived cells for the treatment of myocardial infarction
CD133+ bone marrow-derived stem cells in conjuction with coronary artery bypass grafting
Combination therapy of mononuclear cells with laser for coronary disease
Early endothelial progenitor cells for acute myocardial infarction
Embryonic stem cell-derived cardiomyocyte transplantation for myocardial infarction
Embryonic stem cell-derived cardiomyocytes for treatment of myocardial infarction
Enriched bone marrow-derived progenitor cells for heart diseases
Hearticellgram
Hydrogels with cardiomyocytes for myocardial repair
Mesenchymal precursor cells for cardiovascular diseases
Mesendo, stem cell combination for treatment of cardiovascular diseases
MyoCell
Prochymal
Sca-1-positive cardiac progenitor cells for treatment of myocardial infarction
Stem cell therapy for treatment of acute myocardial infarction
StempeucelAMI
Umbilical cord blood-derived CD133 positive cells for treatment of myocardial infarction
Embryonic/Adult Cultured Cells Related to Myocardial Infarction:
Adipose-derived stem and regenerative cell, PMIDs: 21082397, 22281257
Bone marrow-derived adherent progenitor cells (MultiStem), PMIDs: 22004910, 22052917
Bone marrow-derived autologous CD34+cells (AMR-001), PMID: 21167340
Bone marrow-derived mononuclear cells, PMID: 19002124
Bone marrow-derived mononuclear cells
Peripheral blood-derived hematopoietic stem cells (family)
Bone marrow-derived mononuclear cells, PMIDs: 22137069, 19699857, 20445812, 20524773
Bone marrow-derived CD133+ hematopoietic stem cells
Bone marrow-derived mononuclear cells (family)
Bone marrow-derived mesenchymal stem cells (family)
Bone marrow-derived mononuclear cells (family)
Bone marrow-derived mononuclear cells, PMID: 22834565
Bone marrow-derived mononuclear cells, PMID: 22834565
Bone marrow-derived mononuclear cells (family), PMIDs: 22192151, 21414223
Bone marrow-derived mononuclear cells (family), PMIDs: 16889856, 16382259
Bone marrow-derived mesenchymal stem cells, PMIDs: 16889856, 16382259
Bone marrow-derived mononuclear cells
Bone marrow-derived progenitor cells, PMIDs: 20448133, 16159812, 18293890
Bone marrow-derived mesenchymal stem cells , PMIDs: 21392602, 22940024
Bone marrow-derived mononuclear cells (family), PMIDs: 21392602, 22940024
Porcine bone marrow-derived mesenchymal stem cells, PMIDs: 21392602, 22940024
Cardiosphere-derived cells, PMID: 22336189
Cardiosphere-derived cells, PMIDs: 17283259, 22336189
Bone marrow-derived CD133+ cells, PMID: 17320570
Bone marrow-derived mononuclear cells (family)
eNOS-transfected endothelial progenitor cells, PMIDs: 21362705, 22239631
Peripheral blood-derived endothelial progenitor cells, PMIDs: 21362705, 22239631
Cardiomyocyte-like cells, PMID: 17980256
Cardiomyocyte-like cells, PMID: 22040108
Bone marrow-derived progenitor cells, PMIDs: 23362308, 22936827, 18794392, 16990384, 16990385, 22651868
Bone marrow-derived mesenchymal stem cells (family)
Neonatal rat ventricular cardiomyocytes , PMID: 21783246
Cardiomyocyte-like cells, PMID: 21783246
Mesenchymal Precursor Cells (STRO-3 selected), PMIDs: 20850099, 21155976
Bone marrow-derived mononuclear cells, PMIDs: 21323410, 20631864
Bone marrow-derived mesenchymal stem cells, PMIDs: 21323410, 20631864
Skeletal myoblasts (MyoCell, PMIDs: 19051139, 15615560, 16446778
Cardiac progenitor cells (Sca1+), PMID: 21980409
Bone marrow-derived mononuclear cells (family)
Bone marrow-derived CD34+/CXCR4+ cells
Bone marrow-derived mesenchymal stem cells (Stempeucel, PMID: 18720444
Umbilical cord blood-derived CD133+ cells, PMID: 16195418

Genetic Tests for Myocardial Infarction

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Genetic tests related to Myocardial Infarction:

id Genetic test Affiliating Genes
1 Myocardial Infarction22

Anatomical Context for Myocardial Infarction

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MalaCards organs/tissues related to Myocardial Infarction:

32
Heart, Bone, Endothelial, Brain, Lung, Monocytes, Testes, Neutrophil, Bone marrow, Kidney, Prostate, Whole blood, Thyroid, Liver, Skeletal muscle, Spinal cord, Skin, Myeloid, Pituitary, T cells, Atrioventricular node, Spleen, Small intestine, Uterus, Pons, Cardiac myocytes

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Myocardial Infarction:
id TissueAnatomical CompartmentCell Relevance
1 BoneBone MarrowBone Marrow Stromal Cells Potential therapeutic candidate
2 LimbPelvic GirdleBone Marrow Stromal Cells Potential therapeutic candidate
3 HeartMyocardiumCardiomyocytes Potential therapeutic candidate, affected by disease

Animal Models for Myocardial Infarction or affiliated genes

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MGI Mouse Phenotypes related to Myocardial Infarction:

36 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537610.7GUCY1A3, ITGB3, LTA, GCLM, GCLC, GZMB
2MP:000538510.6CASP1, ITGB3, ACE, MEF2A, ESR1, PTGIS
3MP:001076810.6LTA, GZMB, GJA4, LRP8, GUCY1A3, ESR1
4MP:000539710.6LTA, GCLC, GZMB, CASP1, ITGB3, ACE
5MP:000538710.6GCLC, GZMB, OLR1, CASP1, ACE, PROCR
6MP:000536910.6ESR1, OLR1, CKM, GJA4, GUCY1A3, MEF2A
7MP:000538410.5CASP1, GCLC, CKM, LRP8, ESR1, ACE
8MP:000537010.5LTA, GCLC, ITGB3, ACE, ESR1
9MP:000538810.5ESR1, LTA, GJA4, ITGB3, GUCY1A3, MEF2A
10MP:000200610.4GZMB, ACE, ITGB3, CASP1, ESR1
11MP:000537810.2ESR1, LTA, ITGB3, LRP8, PROCR, ACE

Publications for Myocardial Infarction

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Articles related to Myocardial Infarction:

(show top 50)    (show all 6261)
idTitleAuthorsYear
1
Recurrent Myocardial Infarction After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction. (24188893)
2014
2
Negative Impact of I^-Arrestin-1 on Post-Myocardial Infarction Heart Failure via Cardiac and Adrenal-Dependent Neurohormonal Mechanisms. (24218435)
2014
3
The effects of aging on apoptosis following myocardial infarction. (24279384)
2013
4
Reactive thrombocytosis leading to acute myocardial infarction. (24772734)
2013
5
Acute Myocardial Infarction Caused by Infective Endocarditis. (24316084)
2013
6
The Relationship of Acute Myocardial Infarction With or Without ST-Segment Elevation and Viscosity. (23742945)
2013
7
Endoscopy after acute myocardial infarction: an evaluation of safety. (24096947)
2013
8
The angiotensinogen gene M235T polymorphism and acute myocardial infarction risk: a meta-analysis of 22 studies. (23666149)
2013
9
Comparison of cancer risk associated with low-dose ionizing radiation from cardiac imaging and therapeutic procedures after acute myocardial infarction in women versus men. (23972348)
2013
10
Validity of the GRACE score for 6-month death or reinfarction after presentation with acute myocardial infarction in patients 80 years of age and older. (23965947)
2013
11
Cardiovascular outcomes using intra-aortic balloon pump in high-risk acute myocardial infarction with or without cardiogenic shock: a meta-analysis. (21335478)
2012
12
Lack of association between IL-1 and IL-6 gene polymorphisms and myocardial infarction in Turkish population. (21199393)
2011
13
Diagnostic performance of high-sensitivity troponin T, myeloperoxidase, and pregnancy-associated plasma protein A assays for triage of patients with acute myocardial infarction. (21779191)
2011
14
Myocardial infarction and cerebrovascular accident in patients with retinal vein occlusion. (21402990)
2011
15
Hepatic and renal failure after anterior myocardial infarction induced apical ventricular septal defect. (21274286)
2010
16
Oxidative stress and platelet activation: markers of myocardial infarction in type 2 diabetes mellitus. (19759031)
2010
17
Appraisal of the prognosis in patients with acute myocardial infarction treated with primary percutaneous coronary intervention. (19568720)
2009
18
The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor mediated ex vivo platelet function in acute myocardial infarction. (19637097)
2009
19
Acute inferior myocardial infarction due to cannabis smoking in a young man. (19436220)
2009
20
Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients. (19540141)
2009
21
Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels. (19404549)
2009
22
Plasma adiponectin and resistin levels as predictors of mortality in patients with acute myocardial infarction: data from infarction prognosis study registry. (18997620)
2009
23
Intensive insulin therapy in non-diabetic patients with myocardial infarction and hyperglycemia. INSUCOR study]. (18482525)
2008
24
Quantitative relationship between resting heart rate reduction and magnitude of clinical benefits in post-myocardial infarction: a meta-regression of randomized clinical trials. (17981830)
2007
25
Glomerular filtration rate on admission independently predicts short-term in-hospital mortality after acute myocardial infarction. (16926535)
2006
26
Incidental myocardial infarction in Ehlers-Danlos syndrome type IV? (15813560)
2005
27
No replication of association between estrogen receptor alpha gene polymorphisms and susceptibility to myocardial infarction in a large sample of patients of European descent. (16203927)
2005
28
The risk for myocardial infarction with cyclooxygenase-2 inhibitors. (16230737)
2005
29
Serum levels of endostatin, vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in patients with acute myocardial infarction undergoing early reperfusion therapy. (14965340)
2004
30
Plasma adiponectin levels and risk of myocardial infarction in men. (15082700)
2004
31
Interheart: nine risk factors predict nine out of ten myocardial infarctions]. (15646744)
2004
32
Mitochondrial 5178A/C genotype is associated with acute myocardial infarction. (12520145)
2003
33
Essential thrombocytosis causing a massive myocardial infarction. (12826291)
2003
34
Myoglobin, creatine kinase MB isoforms and creatine kinase MB mass in early diagnosis of myocardial infarction in patients with acute chest pain. (12499000)
2002
35
Annexin V does not represent a diagnostic alternative to myoglobin for early detection of myocardial infarction. (12389712)
2002
36
Acute myocardial infarction: a rare complication of protein C deficiency. (11294179)
2001
37
Soluble P-selectin and the success of thrombolysis in acute myocardial infarction. (11461745)
2001
38
Plasma levels of neuropeptide Y i patients with current myocardial infarction]. (11505745)
2001
39
Angiotensin II type-I receptor and ACE polymorphisms and risk of myocardial infarction in men and women. (11122322)
2000
40
Survival outcomes 1 year after reperfusion therapy with either alteplase or reteplase for acute myocardial infarction: results from the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO) III Trial. (11023929)
2000
41
Intracranial hemorrhage rates and effect of immediate beta-blocker use in patients with acute myocardial infarction treated with tissue plasminogen activator. Participants in the National Registry of Myocardial Infarction-2. (11078295)
2000
42
Elevated plasma levels of interleukin-1 receptor antagonist and interleukin-10 in patients with acute myocardial infarction. (9085939)
1997
43
Effects of ramipril and spironolactone on ventricular remodeling after acute myocardial infarction: randomized and double-blind study]. (9515282)
1997
44
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. (8921781)
1996
45
Indicators of lipoprotein metabolism in normolipemic men after myocardial infarct]. (7489572)
1995
46
Brazilian study with alteplase in acute myocardial infarction--EBRALT]. (8554497)
1995
47
Evidence of a partial escape of renin-angiotensin-aldosterone blockade in patients with acute myocardial infarction treated with ACE inhibitors. (8429112)
1993
48
Exercise-induced precordial ST-segment depression in prior inferior myocardial infarction with single-vessel disease; with special reference to its mechanisms and distinction from multi-vessel disease. (3343075)
1988
49
Anatomic, clinical, and therapeutic features of acute cardiac rupture. Successful surgical management fourteen hours after myocardial infarction. (661371)
1978
50
Contribution to the enzymic diagnosis of acute myocarditis, myocardial infarction and cardiogenic shock. (5384064)
1969

Variations for Myocardial Infarction

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Clinvar genetic disease variations for Myocardial Infarction:

6
id Gene Name Type Significance SNP ID Assembly Location
1ABCC9NM_005691.3(ABCC9): c.2200G> A (p.Val734Ile)single nucleotide variantLikely pathogenicrs61688134GRCh37Chr 12, 22017410: 22017410
2GUCY1A3NM_000856.5(GUCY1A3): c.488dupT (p.Leu163Phefs)duplicationPathogenicGRCh37Chr 4, 156631805: 156631805
3CCT7NM_001166284.1(CCT7): c.1313C> T (p.Ser438Leu)single nucleotide variantPathogenicGRCh37Chr 2, 73479931: 73479931
4LRP8NM_004631.4(LRP8): c.2855G> A (p.Arg952Gln)single nucleotide variantrisk factorrs5174GRCh37Chr 1, 53712727: 53712727

Expression for genes affiliated with Myocardial Infarction

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Expression patterns in normal tissues for genes affiliated with Myocardial Infarction

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Pathways for genes affiliated with Myocardial Infarction

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Pathways related to Myocardial Infarction according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.5GCLC, GCLM
210.5LTA, TNFSF4
3
Show member pathways
10.5LRP8, OLR1, ITGB3, GUCY1A3
4
Show member pathways
creatine-phosphate biosynthesis37
glycine degradation (creatine biosynthesis)37
putrescine biosynthesis III37
spermidine biosynthesis I37
tryptophan degradation via kynurenine37
spermine biosynthesis37
urea cycle37
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I37
tyrosine degradation I37
L-carnitine biosynthesis37
methylthiopropionate biosynthesis37
2-oxoglutarate decarboxylation to succinyl-CoA37
S-methyl-5-thioadenosine degradation II37
10.5GCLM, GCLC, CKM
510.5GUCY1A3, ESR1
6
Show member pathways
10.5LTA, CASP1, TNFSF4
7
Show member pathways
10.5CASP1, TNFSF4, LTA
8
Show member pathways
10.5ITGB3, LTA, MEF2A, ESR1, TNFSF4
9
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
10.5GZMB, CASP1, LTA
10
Show member pathways
10.5LTA, ITGB3, CASP1, GZMB

Compounds for genes affiliated with Myocardial Infarction

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Compounds related to Myocardial Infarction according to GeneCards/GeneDecks:

(show all 34)
idCompoundScoreTop Affiliating Genes
1oxygen44 2411.8GZMB, CKM, CASP1, PTGIS, OLR1, LTA
2lipid4410.8PTGIS, LTA, LRP8, CKM, CASP1, ITGB3
3aspirin44 50 28 2413.8ITGB3, CASP1, PTGIS, ACE
4cisplatin44 50 61 1113.8ESR1, GCLM, GCLC, GZMB, CASP1
5vegf4410.8LTA, CASP1, PROCR, ESR1, ITGB3, GZMB
6nitric oxide44 24 1112.8GCLM, LTA, GZMB, CKM, GJA4, OLR1
7glucose4410.8PTGIS, LTA, GZMB, CKM, OLR1, CASP1
8cholesterol44 28 24 1113.8OLR1, LRP8, PTGIS, ACE, LTA
9diethylmaleate4410.8GCLC, GCLM
10cysteine4410.8CKM, OLR1, ITGB3, CASP1, GCLC, GZMB
114-hydroxynonenal44 2411.8GCLM, CASP1, GCLC
12serine4410.8LTA, CKM, GJA4, CASP1, ITGB3, MEF2A
13retinoic acid44 2411.8GZMB, LTA, GJA4, CASP1, MEF2A, ESR1
14pravastatin44 50 28 24 1114.8CASP1, ACE, OLR1
15calcium44 50 24 1113.8GZMB, LTA, CASP1, ITGB3, ACE, PROCR
16steroid4410.8ESR1, MEF2A, GZMB, LTA, ITGB3
17az 104178086110.8CASP1, GZMB
18sele4410.8ITGB3, ACE
19z-dqmd-fmk61 2811.8CASP1, GZMB
20z-devd-fmk61 2811.8CASP1, GZMB
21glutamate4410.7CKM, GZMB, LTA, MEF2A, CASP1
22cyclosporin a44 28 6112.7GZMB, LTA, CASP1, MEF2A
23lactate4410.7GZMB, CKM, CASP1, LTA
24L-Cysteine24 1111.7GCLM, GCLC
25superoxide44 2411.7CASP1, OLR1, GZMB, PTGIS
26chromium4410.7CASP1, GZMB
27endotoxin4410.6PROCR, CASP1, LTA
28estrogen4410.6ESR1, ITGB3, CASP1, LTA, GZMB
29creatinine4410.6MEF2A, CASP1, CKM, ACE
30z-vad-fmk44 6111.5GZMB, CASP1
31atp44 2811.5ITGB3, CASP1, GZMB, CKM, OLR1
32tyrosine4410.4PTGIS, ITGB3, LRP8, CASP1, LTA, GZMB
33buthionine sulfoximine4410.4GCLM, GCLC
34phosphatidylserine44 28 1112.2CASP1, ITGB3, GZMB

GO Terms for genes affiliated with Myocardial Infarction

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Cellular components related to Myocardial Infarction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integral component of plasma membraneGO:00588710.5TNFSF4, PROCR, ITGB3, OLR1, GJA4
2glutamate-cysteine ligase complexGO:01710910.4GCLM, GCLC
3receptor complexGO:04323510.2ITGB3, OLR1, LRP8

Biological processes related to Myocardial Infarction according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1regulation of mitochondrial depolarizationGO:05190010.8GCLM, GCLC
2response to nitrosative stressGO:05140910.7GCLM, GCLC
3proteolysisGO:00650810.7CASP1, OLR1, GZMB, LRP8
4blood coagulationGO:00759610.7PROCR, GUCY1A3, LRP8, ITGB3, OLR1
5cysteine metabolic processGO:00653410.7GCLC, GCLM
6glutamate metabolic processGO:00653610.7GCLC, GCLM
7regulation of blood vessel sizeGO:05088010.7GCLC, GCLM
8glutathione biosynthetic processGO:00675010.6GCLC, GCLM
9xenobiotic metabolic processGO:00680510.6PTGIS, GCLC, GCLM
10apoptotic mitochondrial changesGO:00863710.5GCLC, GCLM
11cellular nitrogen compound metabolic processGO:03464110.5CKM, GCLC, GCLM
12signal transductionGO:00716510.5TNFSF4, ESR1, CASP1, LTA, LRP8
13glutathione derivative biosynthetic processGO:190168710.4GCLM, GCLC
14sulfur amino acid metabolic processGO:00009610.2GCLM, GCLC

Molecular functions related to Myocardial Infarction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:00516410.5LTA, TNFSF4
2glutamate-cysteine ligase activityGO:00435710.2GCLM, GCLC

Products for genes affiliated with Myocardial Infarction

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  • Antibodies
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Sources for Myocardial Infarction

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet