MCID: MYC058
MIFTS: 28

Myocardial Infarction 2 malady

Categories: Genetic diseases, Cardiovascular diseases

Aliases & Classifications for Myocardial Infarction 2

Aliases & Descriptions for Myocardial Infarction 2:

Name: Myocardial Infarction 2 54
Myocardial Infarction, Susceptibility to, 2 13

Classifications:



External Ids:

OMIM 54 608557

Summaries for Myocardial Infarction 2

MalaCards based summary : Myocardial Infarction 2, also known as myocardial infarction, susceptibility to, 2, is related to myocardial infarction and acute myocardial infarction. An important gene associated with Myocardial Infarction 2 is MCI2 (Myocardial Infarction, Susceptiblity To, 2). The drugs Ticagrelor and Abciximab have been mentioned in the context of this disorder. Affiliated tissues include atrioventricular node and heart.

Description from OMIM: 608557

Related Diseases for Myocardial Infarction 2

Diseases in the Myocardial Infarction family:

Myocardial Infarction 2 Acute Myocardial Infarction
Posterior Myocardial Infarction Myocardial Infarction, Susceptibility to, 1

Diseases related to Myocardial Infarction 2 via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 myocardial infarction 10.4
2 acute myocardial infarction 10.3
3 muscular dystrophy, limb-girdle, type 2c 9.8 MCI2 PLAT
4 cardiogenic shock 9.6

Symptoms & Phenotypes for Myocardial Infarction 2

Clinical features from OMIM:

608557

Drugs & Therapeutics for Myocardial Infarction 2

Drugs for Myocardial Infarction 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 807)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
2
Abciximab Approved Phase 4,Phase 3,Phase 2 143653-53-6
3
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
5
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
6
Tirofiban Approved Phase 4,Phase 3,Phase 2,Phase 1 144494-65-5 60947
7
Colchicine Approved Phase 4,Phase 3,Phase 2 64-86-8 6167 2833
8
Acenocoumarol Approved Phase 4,Phase 3 152-72-7 9052 54676537
9
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
10
Salicylic acid Approved, Vet_approved Phase 4,Phase 3 69-72-7 338
11
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 55142-85-3 5472
12
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
13
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2 188627-80-7 123610
14
Insulin Glargine Approved Phase 4,Phase 3 160337-95-1
15
Metformin Approved Phase 4,Phase 2,Phase 3,Early Phase 1 657-24-9 14219 4091
16
Zinc Approved Phase 4,Phase 3 7440-66-6 32051 23994
17
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
18
Etanercept Approved, Investigational Phase 4,Phase 1,Phase 2 185243-69-0
19
Cilostazol Approved Phase 4,Phase 3 73963-72-1 2754
20
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
21
Nicorandil Approved Phase 4,Phase 3 65141-46-0 47528
22
Clonidine Approved Phase 4,Phase 3,Early Phase 1 4205-90-7 2803
23
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
24
Acarbose Approved, Investigational Phase 4,Phase 3,Phase 2 56180-94-0 441184
25
Pioglitazone Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 111025-46-8 4829
26
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 169590-42-5 2662
27
Ethanol Approved Phase 4,Early Phase 1 64-17-5 702
28
Udenafil Approved, Investigational Phase 4 268203-93-6 6918523
29
Desflurane Approved Phase 4 57041-67-5 42113
30
Isoflurane Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 26675-46-7 3763
31
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 2078-54-8 4943
32
Amlodipine Approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 88150-42-9 2162
33
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 58-93-5 3639
34
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2 137862-53-4 60846
35
Amiloride Approved Phase 4,Phase 3 2016-88-8, 2609-46-3 16231
36
Simvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 79902-63-9 54454
37
Telmisartan Approved, Investigational Phase 4,Phase 3,Phase 2 144701-48-4 65999
38
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2 83-43-2 6741
39
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
40
Tenecteplase Approved Phase 4,Phase 3,Phase 2 191588-94-0
41
Citalopram Approved Phase 4,Phase 2 59729-33-8 2771
42
Acetylcholine Approved Phase 4,Phase 2,Phase 1 51-84-3 187
43
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
44
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 73590-58-6 4594
45
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
46
Phenprocoumon Approved Phase 4,Phase 3 435-97-2 9908 54680692
47
Warfarin Approved Phase 4,Phase 2,Phase 3 81-81-2 6691 54678486
48
Losartan Approved Phase 4,Phase 3,Early Phase 1 114798-26-4 3961
49
Rivaroxaban Approved Phase 4,Phase 2,Phase 3 366789-02-8
50
Lenograstim Approved Phase 4,Phase 2,Phase 3,Phase 1 135968-09-1

Interventional clinical trials:

(show top 50) (show all 2193)
id Name Status NCT ID Phase
1 Cost-effectiveness of Genotype Guided Treatment With Antiplatelet Drugs in STEMI Patients: Optimization of Treatment Unknown status NCT01761786 Phase 4
2 Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Versus Abciximab and SES Versus BMS in AMI Unknown status NCT00229515 Phase 4
3 Customized Choice of Oral P2Y12 Receptor Blocker Unknown status NCT01477775 Phase 4
4 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4
5 Colchicine in ST-elevation Myocardial Infarction Unknown status NCT01936285 Phase 4
6 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
7 Anticoagulation in Stent Intervention Unknown status NCT01141153 Phase 4
8 Peri-Procedural Myocardial Infarction, Platelet Reactivity, Thrombin Generation, and Clot Strength: Differential Effects of Eptifibatide + Bivalirudin Versus Bivalirudin Unknown status NCT00370045 Phase 4
9 Optimizing Infarct Size by Transforming Emergent Stenting Into an Elective Procedure Study Unknown status NCT01462188 Phase 4
10 Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD) Unknown status NCT01035528 Phase 4
11 Multifactorial Intervention in Type 2 Diabetes - Italy Unknown status NCT01240070 Phase 4
12 Intracoronary Bolus Only Compared With Intravenous Bolus and 12-hours Infusion of Abciximab in Non-ST Elevation Myocardial Infarction. Unknown status NCT01080638 Phase 4
13 A Study to Evaluate Safety and Efficacy of the ExcelTM Sirolimus Eluting Stent With a Biodegradable Polymer Versus Sirolimus Eluting Stent With Non-Biodegradable Polymer in the Treatment of Patients With de Novo Coronary Artery Lesions Unknown status NCT00825773 Phase 4
14 MGuard Stent in ST-elevation Myocardial Infarction Unknown status NCT01124942 Phase 4
15 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4
16 Twelve vs 24 Months of Dual Antiplatelet Therapy in Patients With Coronary Revascularization for In-stent Restenosis Unknown status NCT02402491 Phase 4
17 Effect of Modifying Anti-platelet Treatment to Ticagrelor in Patients With Diabetes and Low Response to Clopidogrel Unknown status NCT01643031 Phase 4
18 Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention Unknown status NCT01968577 Phase 4
19 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4
20 Comparison of Biolimus A9 and Everolimus Drug-Eluting Stents in Patients With ST Segment Elevation Myocardial Infarction Unknown status NCT00888758 Phase 4
21 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4
22 IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction Unknown status NCT00157768 Phase 4
23 Efficacy of Early Intensive ROsuvastatin Therapy in Patients With ST-segment Elevation Myocardial Infarction Undergoing PrimARY Percutaneous Coronary Intervention (the ROSEMARY Trial) Unknown status NCT01153334 Phase 4
24 Efficacy Study of Cilostazol Loading in Elective Percutaneous Coronary Intervention Unknown status NCT00938522 Phase 4
25 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4
26 EPIC (Evaluating Perioperative Ischemia Reduction by Clonidine) Unknown status NCT00335582 Phase 4
27 Test Efficacy of Biodegradable and Permanent Limus-Eluting Stents Unknown status NCT01068106 Phase 4
28 Do Cobalt Chrome Stent and Paclitaxel-Eluting Stent Have Equivalent Clinical Result in Non-Complex Lesion? Unknown status NCT00852215 Phase 4
29 Zotarolimus and Everolimus-Eluting Stents ProsPectively Compared in Real World Unknown status NCT00768846 Phase 4
30 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4
31 Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy Unknown status NCT01175486 Phase 4
32 Effects of Celecoxib On Restenosis After Coronary Intervention and Evolution of Atherosclerosis Trial Unknown status NCT00500279 Phase 4
33 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4
34 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4
35 Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL) Unknown status NCT02170103 Phase 4
36 N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure Unknown status NCT00692718 Phase 4
37 Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients Unknown status NCT01198379 Phase 4
38 Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - SAfety & EffectiveneSS of Drug-ElUting Stents & Anti-platelet REgimen Unknown status NCT01267734 Phase 4
39 A Prospective Multicenter Trial Evaluating Helios Biodegradable Polymer SES Safety and Effectiveness in CAD Treatment Unknown status NCT01880879 Phase 4
40 Non-Polymer-Based, Rapamycin-Eluting Stents to Prevent Restenosis Unknown status NCT00152308 Phase 4
41 Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image Unknown status NCT01769482 Phase 4
42 Platelet Function Assessment for Atherothrombotic Patients Unknown status NCT00513149 Phase 4
43 Late Incomplete Stent Apposition Evaluation II: Comparison Between Polimer-based and No-polimer Stent System. IVUS Based Study Unknown status NCT01375855 Phase 4
44 Post-MI PET Scan Imaging of Inflammation Unknown status NCT02281305 Phase 4
45 Desflurane-induced Myocardial Protection Unknown status NCT02019797 Phase 4
46 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4
47 Regression of Fatty Heart by Valsartan Therapy Unknown status NCT00745953 Phase 4
48 Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients Unknown status NCT01011660 Phase 4
49 Steroids In caRdiac Surgery Trial (SIRS Trial) Unknown status NCT00427388 Phase 4
50 Comparison of Ticagrelor And Clopidogrel on Inflammatory Biomarkers And Vascular Endothelial Function Unknown status NCT02123004 Phase 4

Search NIH Clinical Center for Myocardial Infarction 2

Genetic Tests for Myocardial Infarction 2

Anatomical Context for Myocardial Infarction 2

MalaCards organs/tissues related to Myocardial Infarction 2:

39
Atrioventricular Node, Heart

Publications for Myocardial Infarction 2

Articles related to Myocardial Infarction 2:

(show all 32)
id Title Authors Year
1
Letter by Fresco regarding article "Primary angioplasty versus fibrinolysis in acute myocardial infarction: long-term follow-up in the Danish Acute Myocardial Infarction 2 trial". ( 21173360 )
2010
2
Primary angioplasty versus fibrinolysis in acute myocardial infarction: long-term follow-up in the Danish acute myocardial infarction 2 trial. ( 20308618 )
2010
3
Timing of ischemic onset estimated from the electrocardiogram is better than historical timing for predicting outcome after reperfusion therapy for acute anterior myocardial infarction: a DANish trial in Acute Myocardial Infarction 2 (DANAMI-2) substudy. ( 17584552 )
2007
4
Smoking and mortality following acute myocardial infarction: results from the National Registry of Myocardial Infarction 2 (NRMI 2). ( 11906686 )
2002
5
Use of emergency medical services in acute myocardial infarction and subsequent quality of care: observations from the National Registry of Myocardial Infarction 2. ( 12473545 )
2002
6
A risk model derived from the National Registry of Myocardial Infarction 2 database for predicting mortality after coronary artery bypass grafting during acute myocardial infarction. ( 12088769 )
2002
7
The use of intra-aortic balloon counterpulsation in patients with cardiogenic shock complicating acute myocardial infarction: data from the National Registry of Myocardial Infarction 2. ( 11376306 )
2001
8
Death or nonfatal stroke in patients with acute myocardial infarction treated with tissue plasminogen activator. Participants in the National Registry of Myocardial Infarction 2. ( 11230850 )
2001
9
Treatment and outcomes of left bundle-branch block patients with myocardial infarction who present without chest pain. National Registry of Myocardial Infarction 2 Investigators. ( 10987588 )
2000
10
The volume of primary angioplasty procedures and survival after acute myocardial infarction. National Registry of Myocardial Infarction 2 Investigators. ( 10824077 )
2000
11
Payer status and the utilization of hospital resources in acute myocardial infarction: a report from the National Registry of Myocardial Infarction 2. ( 10737281 )
2000
12
Impact of history of diabetes mellitus on hospital mortality in men and women with first acute myocardial infarction. The National Registry of Myocardial Infarction 2 Participants. ( 10856398 )
2000
13
Reperfusion therapy for acute myocardial infarction: observations from the National Registry of Myocardial Infarction 2. ( 10423667 )
1999
14
Early use of ACE inhibitors in the treatment of acute myocardial infarction in the United States: experience from the National Registry of Myocardial Infarction 2. National Registry of Myocardial Infarction 2 participants. ( 10569326 )
1999
15
Sex-based differences in early mortality after myocardial infarction. National Registry of Myocardial Infarction 2 Participants. ( 10413733 )
1999
16
The association between the on-site availability of cardiac procedures and the utilization of those services for acute myocardial infarction by payer group. The National Registry of Myocardial Infarction 2 Investigators. ( 10492841 )
1999
17
A comparison of the national registry of myocardial infarction 2 with the cooperative cardiovascular project. ( 10362189 )
1999
18
Management and outcomes for black patients with acute myocardial infarction in the reperfusion era. National Registry of Myocardial Infarction 2 Investigators. ( 9817474 )
1998
19
Presenting characteristics, treatment patterns, and clinical outcomes of non-black minorities in the National Registry of Myocardial Infarction 2. ( 9817473 )
1998
20
Risk for intracranial hemorrhage after tissue plasminogen activator treatment for acute myocardial infarction. Participants in the National Registry of Myocardial Infarction 2. ( 9786806 )
1998
21
Use of angiotensin-converting enzyme inhibitors at discharge in patients with acute myocardial infarction in the United States: data from the National Registry of Myocardial Infarction 2. ( 9708461 )
1998
22
Bundle-branch block and in-hospital mortality in acute myocardial infarction. National Registry of Myocardial Infarction 2 Investigators. ( 9841600 )
1998
23
Use of reperfusion therapy for acute myocardial infarction in the United States: data from the National Registry of Myocardial Infarction 2. ( 9537341 )
1998
24
The prehospital electrocardiogram in acute myocardial infarction: is its full potential being realized? National Registry of Myocardial Infarction 2 Investigators. ( 9060884 )
1997
25
Recurrent myocardial infarction. 2. Possibilities of prediction. ( 4029186 )
1985
26
Thrombolytic therapy. A new strategy for the treatment of acute myocardial infarction (2). ( 6236369 )
1984
27
Dissociation of the atrioventricular node in acute inferior wall myocardial infarction. 2. Longitudinal dissociation (dual atrioventricular nodal pathways). ( 648218 )
1978
28
The clinical significance of bundle branch block complicating acute myocardial infarction. 2. Indications for temporary and permanent pacemaker insertion. ( 688580 )
1978
29
Myocardial infarction. 2. ( 4844740 )
1974
30
Management of dysrhythmias associated with acute myocardial infarction. 2. ( 5130352 )
1971
31
Treatment of acute myocardial infarction. 2. Ventricular ectopic arrhythmias. ( 4194547 )
1970
32
Diseases of the heart and blood-vessels. Recovery after myocardial infarction--2. ( 5941505 )
1966

Variations for Myocardial Infarction 2

Expression for Myocardial Infarction 2

Search GEO for disease gene expression data for Myocardial Infarction 2.

Pathways for Myocardial Infarction 2

GO Terms for Myocardial Infarction 2

Sources for Myocardial Infarction 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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