MCID: MYC065
MIFTS: 15

Myocardial Infarction, Decreased malady

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Summaries for Myocardial Infarction, Decreased

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MalaCards based summary: Myocardial Infarction, Decreased is related to myocardial infarction and acute myocardial infarction. An important gene associated with Myocardial Infarction, Decreased is F7 (coagulation factor VII (serum prothrombin conversion accelerator)), and among its related pathways are Platelet homeostasis and Hemostasis. Affiliated tissues include endothelial.

Description from OMIM:46 608446

Aliases & Classifications for Myocardial Infarction, Decreased

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Myocardial Infarction, Decreased, Aliases & Descriptions:

Name: Myocardial Infarction, Decreased 46


Related Diseases for Myocardial Infarction, Decreased

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Diseases related to Myocardial Infarction, Decreased via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1myocardial infarction31.2F7
2acute myocardial infarction10.3
3patent foramen ovale10.2
4hyperglycemia10.2
5cardiac rupture10.2
6endotheliitis10.2

Graphical network of diseases related to Myocardial Infarction, Decreased:



Diseases related to myocardial infarction, decreased

Symptoms for Myocardial Infarction, Decreased

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Clinical features from OMIM:

608446

Drugs & Therapeutics for Myocardial Infarction, Decreased

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Drug clinical trials:

Search ClinicalTrials for Myocardial Infarction, Decreased

Search NIH Clinical Center for Myocardial Infarction, Decreased

Genetic Tests for Myocardial Infarction, Decreased

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Anatomical Context for Myocardial Infarction, Decreased

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MalaCards organs/tissues related to Myocardial Infarction, Decreased:

32
Endothelial

Animal Models for Myocardial Infarction, Decreased or affiliated genes

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Publications for Myocardial Infarction, Decreased

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Articles related to Myocardial Infarction, Decreased:

idTitleAuthorsYear
1
Using a single cut-off for stress hyperglycemia in myocardial infarction decreases its prognostic value particularly in diabetes. (24211277)
2014
2
Early initiation of low-dose atorvastatin treatment after an acute ST-elevated myocardial infarction, decreases inflammatory process and prevents endothelial injury and activation. (18187214)
2009

Variations for Myocardial Infarction, Decreased

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Clinvar genetic disease variations for Myocardial Infarction, Decreased:

6
id Gene Name Type Significance SNP ID Assembly Location
1ABCC9NM_005691.3(ABCC9): c.2200G> A (p.Val734Ile)single nucleotide variantLikely pathogenicrs61688134GRCh37Chr 12, 22017410: 22017410
2GUCY1A3NM_000856.5(GUCY1A3): c.488dupT (p.Leu163Phefs)duplicationPathogenicGRCh37Chr 4, 156631805: 156631805
3CCT7NM_001166284.1(CCT7): c.1313C> T (p.Ser438Leu)single nucleotide variantPathogenicGRCh37Chr 2, 73479931: 73479931
4LRP8NM_004631.4(LRP8): c.2855G> A (p.Arg952Gln)single nucleotide variantrisk factorrs5174GRCh37Chr 1, 53712727: 53712727

Expression for genes affiliated with Myocardial Infarction, Decreased

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Expression patterns in normal tissues for genes affiliated with Myocardial Infarction, Decreased

Search GEO for disease gene expression data for Myocardial Infarction, Decreased.

Pathways for genes affiliated with Myocardial Infarction, Decreased

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Pathways related to Myocardial Infarction, Decreased according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1GUCY1A3, LRP8
2
Show member pathways
8.6F7, GUCY1A3, LRP8

Compounds for genes affiliated with Myocardial Infarction, Decreased

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GO Terms for genes affiliated with Myocardial Infarction, Decreased

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Biological processes related to Myocardial Infarction, Decreased according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1proteolysisGO:0065089.4F7, LRP8
2blood coagulationGO:0075968.3F7, GUCY1A3, LRP8

Products for genes affiliated with Myocardial Infarction, Decreased

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  • Antibodies
  • Proteins
  • Lysates

Sources for Myocardial Infarction, Decreased

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet