MCID: MYC001
MIFTS: 17

Myoclonic Cerebellar Dyssynergia

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Myoclonic Cerebellar Dyssynergia

MalaCards integrated aliases for Myoclonic Cerebellar Dyssynergia:

Name: Myoclonic Cerebellar Dyssynergia 12 41 14 69
Dyssynergia Cerebellaris Myoclonica 12 49 50
Dyssynergia Cerebellaris Progressiva 49 50
Dentate Cerebellar Ataxia 49 50
Primary Dentatum Atrophy 49 50
Dentatorubral Atrophy 49 50
Ramsay Hunt Cerebellar Syndrome 49
Progressive Cerebellar Tremor 12
Progressive Myoclonus Ataxia 49
Myoclonus and Ataxia 49

Classifications:



External Ids:

Disease Ontology 12 DOID:12707
ICD10 32 G11.1
MeSH 41 D002527
UMLS 69 C0007761

Summaries for Myoclonic Cerebellar Dyssynergia

NINDS : 50 Dyssynergia Cerebellaris Myoclonica refers to a collection of rare, degenerative, neurological disorders characterized by epilepsy, cognitive impairment, myoclonus, and progressive ataxia.  Symptoms include seizures, tremor, and reduced muscle coordination.  Onset of the disorder generally occurs in early adulthood.  Tremor may begin in one extremity and later spread to involve the entire voluntary muscular system.  Arms are usually more affected than legs.  Some of the cases are due to mitochondrial abnormalities.

MalaCards based summary : Myoclonic Cerebellar Dyssynergia, also known as dyssynergia cerebellaris myoclonica, is related to cerebelloparenchymal disorder v and gosr2-related progressive myoclonus ataxia. An important gene associated with Myoclonic Cerebellar Dyssynergia is MT-TK (Mitochondrially Encoded TRNA Lysine). Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Myoclonic Cerebellar Dyssynergia

Diseases related to Myoclonic Cerebellar Dyssynergia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 cerebelloparenchymal disorder v 11.4
2 gosr2-related progressive myoclonus ataxia 11.4
3 ramsay hunt syndrome i 11.4
4 myoclonus and ataxia 10.5
5 mitochondrial encephalomyopathy 10.3
6 encephalomyopathy 10.3
7 myoclonus 10.3
8 tay-sachs disease 9.4 CTSA VIM

Graphical network of the top 20 diseases related to Myoclonic Cerebellar Dyssynergia:



Diseases related to Myoclonic Cerebellar Dyssynergia

Symptoms & Phenotypes for Myoclonic Cerebellar Dyssynergia

GenomeRNAi Phenotypes related to Myoclonic Cerebellar Dyssynergia according to GeneCards Suite gene sharing:

25 (show all 19)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.62 VIM
2 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.62 VIM
3 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.62 VIM
4 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.62 VIM CTSA
5 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.62 VIM
6 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.62 VIM
7 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.62 CTSA
8 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.62 CTSA
9 Increased shRNA abundance (Z-score > 2) GR00366-A-215 9.62 CTSA
10 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.62 CTSA
11 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.62 VIM
12 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.62 VIM
13 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.62 CTSA
14 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.62 CTSA
15 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.62 VIM
16 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.62 CTSA
17 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.62 VIM
18 Increased shRNA abundance (Z-score > 2) GR00366-A-93 9.62 CTSA
19 Increased shRNA abundance (Z-score > 2) GR00366-A-96 9.62 CTSA

Drugs & Therapeutics for Myoclonic Cerebellar Dyssynergia

Search Clinical Trials , NIH Clinical Center for Myoclonic Cerebellar Dyssynergia

Cochrane evidence based reviews: myoclonic cerebellar dyssynergia

Genetic Tests for Myoclonic Cerebellar Dyssynergia

Anatomical Context for Myoclonic Cerebellar Dyssynergia

Publications for Myoclonic Cerebellar Dyssynergia

Articles related to Myoclonic Cerebellar Dyssynergia:

# Title Authors Year
1
Clinical and electroencephalographic investigations in myoclonic cerebellar dyssynergia. ( 14411893 )
1959

Variations for Myoclonic Cerebellar Dyssynergia

Expression for Myoclonic Cerebellar Dyssynergia

Search GEO for disease gene expression data for Myoclonic Cerebellar Dyssynergia.

Pathways for Myoclonic Cerebellar Dyssynergia

GO Terms for Myoclonic Cerebellar Dyssynergia

Sources for Myoclonic Cerebellar Dyssynergia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....