MCID: MYF001
MIFTS: 29

Myofibroma malady

Cancer diseases category

Summaries for Myofibroma

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34MalaCards
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MalaCards: Myofibroma, also known as lipoleiomyoma, is related to sarcoma and uterine corpus lipoleiomyoma. An important gene associated with Myofibroma is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways are Cytoskeletal Signaling and Myometrial Relaxation and Contraction Pathways. The compound actomyosin have been mentioned in the context of this disorder. Affiliated tissues include bone, smooth muscle and testes, and related mouse phenotype muscle.

Aliases & Classifications for Myofibroma

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9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

myofibroma 9 11 63
lipoleiomyoma 9


External Ids:

Disease Ontology9 DOID:4386
SNOMED-CT59 44598004, 128917003
MeSH36 D047708

Related Diseases for Myofibroma

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Myofibroma:



Diseases related to myofibroma

Symptoms for Myofibroma

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Drugs & Therapeutics for Myofibroma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Myofibroma

Search CenterWatch for Myofibroma

Genetic Tests for Myofibroma

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Anatomical Context for Myofibroma

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34MalaCards
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MalaCards organs/tissues related to Myofibroma:

34
Bone, Smooth muscle, Testes, Colon, Breast, Skin, Testis, Tongue

Animal Models for Myofibroma or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Myofibroma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.1CALD1, ACTC1

Publications for Myofibroma

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53PubMed
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Articles related to Myofibroma:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Myofibroma of the tongue: a case suggesting autosomal dominant inheritance. (23850370)
2014
2
Submandibular myofibroma: a case report. (23404191)
2013
3
Solitary myofibroma of the mandible: an immunohistochemical and ultrastructural study with a review of the literature. (24213519)
2013
4
Intraosseous myofibroma of mandible: A rarity of jaws: With clinical, radiological, histopathological and immunohistochemical features. (23798845)
2013
5
A case of congenital solitary testicular myofibroma associated with an undescended testis. (23856846)
2013
6
A case of congenital myofibroma of the orbit presenting at birth. (23387453)
2013
7
Myofibroma of the oral mucosa: a case report. (22179419)
2012
8
Myofibroma of the mandible in an infant: case report, review of the literature, and discussion. (21958664)
2012
9
Solitary infantile myofibroma of the orbit. (20977698)
2011
10
Clinical pathologic conference case 6: infantile myofibroma. (21892764)
2011
11
Congenital cranio-orbital myofibroma. (21088629)
2011
12
Penile myofibroma occurring in a dorsal hood prepuce. (21168192)
2011
13
A large tumor on the scalp of a newborn. Solitary myofibroma. (21182644)
2010
14
Myofibroma of the oral cavity. A rare spindle cell neoplasm. (20038894)
2010
15
Myofibroma of the conjunctiva invading the cornea in infancy. (21214145)
2010
16
Infantile myofibroma of the pharynx presenting with severe upper airway obstruction in a child. (20071800)
2010
17
Myofibroma of the gingiva: report of a case. (20578664)
2010
18
Myofibroma of the external auditory canal: report of an adult case. (20163056)
2009
19
Intraosseous myofibroma simulating an odontogenic lesion. (19550103)
2009
20
Solitary myofibroma of the skull presenting outside infancy. (18714810)
2008
21
Adult cutaneous myofibroma. (18187828)
2008
22
Solitary infantile myofibromatosis (myofibroma) of the skull: a case presentation and histopathological differential diagnosis. (18549297)
2008
23
Myofibroma of the mandible. (19246965)
2008
24
Masson trichrome stain helps differentiate myofibroma from smooth muscle lesions in the head and neck region. (18926943)
2008
25
Solitary myofibroma of the sclera. (17198028)
2007
26
Complex regional pain syndrome after solitary adult myofibroma excision. (17659013)
2007
27
Oral and maxillofacial pathology case of the month. Myofibroma. (18038860)
2007
28
Clinico-pathologic correlations of myofibroblastic tumors of the oral cavity. II. Myofibroma and myofibromatosis of the oral soft tissues. (17448141)
2007
29
Myofibroma of the proximal nail fold: an uncommon neoplasm. (16648928)
2006
30
Solitary orbital infantile myofibroma: a case report and review of the literature. (16814188)
2006
31
Solitary intraosseous orbital myofibroma in four cases. (16855503)
2006
32
Solitary infantile myofibroma of the orbital bone. (16181295)
2005
33
Testing your diagnostic skills. Case no. 1: myofibroma. (17632922)
2005
34
Solitary infantile gastrointestinal myofibroma: case report. (16080950)
2005
35
Soft tissue solitary adult myofibroma in an intervertebral foramen. (15550108)
2004
36
Myofibroma of the cheek: a case report. (15266876)
2004
37
Solitary myofibroma of the eyelid. (14738496)
2004
38
Infantile myofibroma in a prematurely born twin: a case report. (12869160)
2003
39
Myofibroma of the upper arm in a 52-year-old woman. (11904694)
2002
40
"Infantile" myofibroma of the oral cavity: report of case. (11289185)
2001
41
Myofibroma/myofibromatosis is the most common fibrous proliferation of infancy and childhood. (10889935)
2000
42
Solitary intracranial myofibroma in a child. (10475760)
1999
43
Solitary intraosseous infantile myofibroma of the orbital roof. (9823360)
1998
44
Solitary cutaneous myofibroma of the glans penis. (8806969)
1996
45
Facial myofibroma of the newborn simulating sarcoma]. (9615114)
1996
46
Cutaneous adult myofibroma: a vascular neoplasm. (8915853)
1996
47
Solitary myofibroma in adults: clinicopathological analysis of a series. (8514276)
1993
48
Solitary cutaneous "infantile" myofibroma in a 49-year-old woman. (2338335)
1990
49
CLINICAL pathologic conference; cystic myofibroma. (14804073)
1951
50
X. Myofibroma of the Large Intestine. (17861846)
1906

Variations for Myofibroma

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Expression for genes affiliated with Myofibroma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myofibroma

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Pathways for genes affiliated with Myofibroma

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51PathCards, 5Cell Signaling Technology, 39NCBI BioSystems Database, 56Reactome
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Pathways related to Myofibroma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1CALD1, ACTC1
2
Show member pathways
Calcium Regulation in the Cardiac Cell39
9.1CALD1, ACTC1
3
Show member pathways
9.1CALD1, ACTC1

Compounds for genes affiliated with Myofibroma

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46Novoseek
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Compounds related to Myofibroma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1actomyosin469.1CALD1, ACTC1

GO Terms for genes affiliated with Myofibroma

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17Gene Ontology
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Molecular functions related to Myofibroma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1myosin bindingGO:0170229.1CALD1, ACTC1

Products for genes affiliated with Myofibroma

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Sources for Myofibroma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet