MCID: MYP006
MIFTS: 41

Myopia malady

Genetic diseases, Eye diseases, Rare diseases categories

Summaries for Myopia

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Wikipedia:63 Myopia (Ancient more...

MalaCards based summary: Myopia, also known as myopia, susceptibility to, is related to astigmatism and hyperopia. An important gene associated with Myopia is ZNF644 (zinc finger protein 644). Affiliated tissues include eye, endothelial and retina.

Disease Ontology:9 A refractive error characterized by the inability to see farther objects clearly.

Aliases & Classifications for Myopia

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 22GTR, 27ICD9CM, 55SNOMED-CT, 33MeSH, 25ICD10
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Myopia, Aliases & Descriptions:

Name: Myopia 9 11 43 60
Myopia, Susceptibility to 22
Short-Sightedness 9
 
Near-Sightedness 9
Near Vision 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology9 DOID:11830
ICD9CM27 367.1
SNOMED-CT55 155133003, 57190000
MeSH33 D009216
ICD1025 H52.1

Related Diseases for Myopia

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Diseases in the Myopia family:

Myopia 14 Myopia 21, Autosomal Dominant
Myopia 8 Myopia 23, Autosomal Recessive
Myopia 9 Myopia 22, Autosomal Dominant
Myopia 10 Myopia 7
Myopia 24, Autosomal Dominant Myopia 20, Autosomal Dominant
Myopia 6 Myopia, Autosomal

Diseases related to Myopia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 392)
idRelated DiseaseScoreTop Affiliating Genes
1astigmatism10.7
2hyperopia10.6
3choroiditis10.6
4retinitis10.6
5refractive error10.6
6degenerative myopia10.5
7polydactyly myopia syndrome10.4
8cataract10.4
9macular holes10.3
10blepharoptosis myopia ectopia lentis10.3
11open-angle glaucoma10.3
12amblyopia10.3
13esotropia10.3
14retinal detachment10.3
15blindness10.3
16myopia 610.3
17anisometropia10.3
18donnai-barrow syndrome10.2
19myopia 810.2
20myopia 910.2
21myopia 1010.2
22myopia 710.2
23night blindness10.2
24strabismus10.2
25myopia 1410.2
26myopia 21, autosomal dominant10.2
27epiphyseal dysplasia, multiple, with myopia and deafness10.2
28presbyopia10.2
29congenital stationary night blindness10.2
30x-linked congenital stationary night blindness10.2
31aplasia cutis myopia10.2
32aniseikonia10.2
33trachoma10.2
34myopia 20, autosomal dominant10.2
35deafness and myopia10.2
36retinoschisis10.2
37coloboma10.2
38exotropia10.2
39dandy-walker malformation with mental retardation, macrocephaly, myopia and brachytelephalangy10.2
40sinus node disease and myopia10.2
41endotheliitis10.2
42myopia, high, with cataract and vitreoretinal degeneration10.1
43myopia 22, autosomal dominant10.1
44sed congenita10.1
45corneal ectasia10.1
46eye disease10.1
47mousa al din al nassar syndrome10.1
48facial dysmorphism - macrocephaly - myopia - dandy-walker malformation10.1
49osteopenia - myopia - hearing loss - intellectual disability - facial dysmorphism10.1
50ehlers-danlos syndrome, type vi10.1

Graphical network of the top 20 diseases related to Myopia:



Diseases related to myopia

Symptoms for Myopia

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Drugs & Therapeutics for Myopia

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Drug clinical trials:

Search ClinicalTrials for Myopia

Search NIH Clinical Center for Myopia

Genetic Tests for Myopia

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Genetic tests related to Myopia:

id Genetic test Affiliating Genes
1 Myopia22

Anatomical Context for Myopia

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MalaCards organs/tissues related to Myopia:

31
Eye, Endothelial, Retina, Testes, Heart, Cortex

Animal Models for Myopia or affiliated genes

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Publications for Myopia

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Articles related to Myopia:

(show top 50)    (show all 886)
idTitleAuthorsYear
1
Macular parameters of Stratus optical coherence tomography for assessing glaucoma in high myopia. (25349103)
2014
2
Correlation between central corneal thickness and myopia in Taiwan. (24388054)
2014
3
Comparative Evaluation of Higher-Order Aberrations and Corneal Asphericity Between Wavefront-guided and Aspheric LASIK for Myopia. (25375851)
2014
4
Generational difference of refractive error and risk factors in the Handan Offspring Myopia Study. (25097244)
2014
5
Peripheral optical quality and myopia progression in children. (24253497)
2014
6
Measurement of Scleral Thickness using Swept-Source Optical Coherence Tomography in Open-Angle Glaucoma Patients with Myopia. (24412142)
2014
7
Association of Lumican gene polymorphism with high myopia: a meta-analysis. (24061151)
2013
8
Co-existent choroidal neovascular membrane and macular hole in pathologic myopia: a long follow-up clinical outcome and literature review. (24392342)
2013
9
Retinal nerve fiber layer in primary open-angle glaucoma with high myopia determined by optical coherence tomography and scanning laser polarimetry. (23595371)
2013
10
Peripheral defocus and myopia progression in myopic children randomly assigned to wear single vision and progressive addition lenses. (23838771)
2013
11
Clear lens phacoemulsification combined with vitrectomy to correct high myopia: four years of follow-up. (23257681)
2013
12
Effect of myopia and age on optic disc margin anatomy within the parapapillary atrophy area. (23851575)
2013
13
Heritability of myopia and ocular biometrics in Koreans: the healthy twin study. (23620424)
2013
14
The effect of the Chinese Cultural Revolution and Great Leap Forward on the prevalence of myopia. (24197389)
2013
15
Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. (23933737)
2013
16
Aqueous Concentrations of Vascular Endothelial Growth Factor in Eyes with High Myopia with and without Choroidal Neovascularization. (23533702)
2013
17
Myopia control with orthokeratology contact lenses in Spain: a comparison of vision-related quality-of-life measures between orthokeratology contact lenses and single-vision spectacles. (23392299)
2013
18
Femtosecond (FS) laser vision correction procedure for moderate to high myopia: a prospective study of ReLEx(Ar) flex and comparison with a retrospective study of FS-laser in situ keratomileusis. (22512839)
2013
19
A contralateral, randomized comparison of optimized prolate ablation and conventional LASIK for myopia with the NIDEK excimer laser platform. (22767164)
2012
20
Baseline characteristics of nearwork-induced transient myopia. (23187872)
2012
21
The impact of parental myopia on myopia in Chinese children: population-based evidence. (22922777)
2012
22
Atropine for the treatment of childhood myopia: safety and efficacy of 0.5%, 0.1%, and 0.01% doses (Atropine for the Treatment of Myopia 2). (21963266)
2012
23
Ten SNPs of PAX6, Lumican, and MYOC genes are not associated with high myopia in Han Chinese. (22809227)
2012
24
High myopia as a risk factor in primary open angle glaucoma. (23275912)
2012
25
On the dangers of methodolatry, moral hazard and myopia in research. (22176663)
2012
26
Acquired optic nerve and peripapillary pits in pathologic myopia. (22494632)
2012
27
Prevalence of myopia in a population with malocclusions. (23046255)
2012
28
Prevalence of myopia and its association with diabetic retinopathy in subjects with type II diabetes mellitus: A population-based study. (22993463)
2012
29
Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. (21095009)
2011
30
Nature and nurture: the complex genetics of myopia and refractive error. (21155761)
2011
31
A functional polymorphism at 3'UTR of the PAX6 gene may confer risk for extreme myopia in the Chinese. (21421876)
2011
32
Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population. (21640322)
2011
33
Pigmented free-floating vitreous cyst in a patient with high myopia and uveal coloboma simulating choroidal melanoma. (21485975)
2011
34
Age-related changes of phoria myopia in patients with intermittent exotropia. (19184303)
2009
35
Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. (19836009)
2009
36
Myocilin polymorphisms and high myopia in subjects of European origin. (19180258)
2009
37
Linkage analysis of high myopia susceptibility locus in 26 families. (19122830)
2008
38
Prevalence of myopia and hyperopia among urban and rural schoolchildren in Poland. (19127805)
2008
39
Pupillography of relative afferent pupillary defects in amblyopia associated with peripapillary myelinated nerve fibers and myopia. (18825905)
2008
40
Active cyclotorsion error correction during LASIK for myopia and myopic astigmatism with the NIDEK EC-5000 CX III laser. (18047004)
2007
41
Evidence for delayed presbyopia after photorefractive keratectomy for myopia. (16650666)
2006
42
The role of the retinal pigment epithelium in eye growth regulation and myopia: a review. (16079001)
2005
43
X-linked high myopia associated with cone dysfunction. (15197065)
2004
44
Fixation linked hypotropia in high myopia. A report of two similar cases. (12597767)
2003
45
Myopia and models and mechanisms of refractive error control. (12064076)
2002
46
Volume estimation of excimer laser tissue ablation for correction of spherical myopia and hyperopia. (11980859)
2002
47
Intraocular lens implantation and laser in situ keratomileusis (bioptics) to correct high myopia and hyperopia with astigmatism. (11316030)
2001
48
Clinical features and surgery for acquired progressive esotropia associated with severe myopia. (10071152)
1999
49
A second locus for familial high myopia maps to chromosome 12q. (9792869)
1998
50
Flicker parameters are different for suppression of myopia and hyperopia. (9373666)
1997

Variations for Myopia

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Expression for genes affiliated with Myopia

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Search GEO for disease gene expression data for Myopia.

Pathways for genes affiliated with Myopia

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Compounds for genes affiliated with Myopia

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GO Terms for genes affiliated with Myopia

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Biological processes related to Myopia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to stimulusGO:00508969.9CLDN19, NYX

Products for genes affiliated with Myopia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Myopia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet