MCID: MYP006
MIFTS: 57

Myopia malady

Categories: Genetic diseases, Eye diseases, Rare diseases

Aliases & Classifications for Myopia

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Aliases & Descriptions for Myopia:

Name: Myopia 10 47 12 36 65
Myopia, Susceptibility to 24
Short-Sightedness 10
 
Near-Sightedness 10
Near Vision 10

Classifications:



External Ids:

Disease Ontology10 DOID:11830
ICD1027 H52.1
ICD9CM29 367.1
SNOMED-CT59 155133003, 57190000
MeSH36 D009216
NCIt42 C102533
UMLS65 C0027092

Summaries for Myopia

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Wikipedia:68 Myopia, also known as near-sightedness and short-sightedness, is a condition of the eye where the light... more...

MalaCards based summary: Myopia, also known as myopia, susceptibility to, is related to marshall syndrome and stickler syndrome, type ii, and has symptoms including aniseikoniaand aniseikonia. An important gene associated with Myopia is SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein), and among its related pathways are Protein digestion and absorption and ECM proteoglycans. Affiliated tissues include eye, retina and heart, and related mouse phenotypes are vision/eye and nervous system.

Disease Ontology:10 A refractive error characterized by the inability to see farther objects clearly.

Related Diseases for Myopia

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Diseases in the Myopia family:

Myopia 14 Myopia 21, Autosomal Dominant
Myopia 8 Myopia 23, Autosomal Recessive
Myopia 9 Myopia 22, Autosomal Dominant
Myopia 10 Myopia 7
Myopia 24, Autosomal Dominant Myopia 20, Autosomal Dominant
Myopia 6 Myopia, Autosomal

Diseases related to Myopia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 232)
idRelated DiseaseScoreTop Affiliating Genes
1marshall syndrome32.6COL11A1, COL2A1
2stickler syndrome, type ii30.6COL11A1, COL2A1
3stickler syndrome30.2COL11A1, COL2A1, FMOD
4deafness and myopia12.2
5degenerative myopia12.2
6epiphyseal dysplasia, multiple, with myopia and deafness12.0
7myopia 21, autosomal dominant12.0
8myopia 612.0
9myopia, high, with cataract and vitreoretinal degeneration12.0
10polydactyly myopia syndrome12.0
11myopia 23, autosomal recessive12.0
12myopia 22, autosomal dominant12.0
13myopia 1412.0
14myopia 812.0
15myopia 912.0
16myopia 1012.0
17myopia 712.0
18myopia 24, autosomal dominant12.0
19myopia 20, autosomal dominant11.9
20x-linked cone dysfunction syndrome with myopia11.9
21blepharoptosis myopia ectopia lentis11.9
22aplasia cutis myopia11.8
23dandy-walker malformation with mental retardation, macrocephaly, myopia and brachytelephalangy11.8
24myopia, autosomal11.8
25optic atrophy opthalmoplegia ptosis deafness myopia11.7
26sinus node disease and myopia11.7
27myopia, x-linked11.7
28facial dysmorphism-macrocephaly-myopia-dandy-walker malformation syndrome11.7
29autosomal dominant myopia-midfacial retrusion-sensorineural hearing loss-rhizomelic dysplasia syndrome11.7
30osteopenia-myopia-hearing loss-intellectual disability-facial dysmorphism syndrome11.7
31rare isolated myopia11.7
32x-linked congenital stationary night blindness11.5
33achromatopsia-311.4
34hamamy syndrome11.4
35night blindness, congenital stationary , 1a, x-linked11.3
36donnai-barrow syndrome11.2
37knobloch syndrome11.1
38mousa al din al nassar syndrome10.9
39noble bass sherman syndrome10.9
40refractive error10.8
41schwartz-jampel syndrome, type 110.7
42gastrocutaneous syndrome10.7
43rozin hertz goodman syndrome10.7
44multiple epiphyseal dysplasia, beighton type10.7
45spondyloepiphyseal dysplasia, macdermot type10.7
46craniofacial dysplasia-osteopenia syndrome10.7
47choroidal sclerosis10.7COL2A1, ZNF644
48congenital trochlear nerve palsy10.7LRPAP1, P3H2, SCO2
49trichuriasis10.6COL11A1, COL2A1
50dystrophies primarily involving the retinal pigment epithelium10.6COL11A1, COL2A1

Graphical network of the top 20 diseases related to Myopia:



Diseases related to myopia

Symptoms for Myopia

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UMLS symptoms related to Myopia:


aniseikonia

Drugs & Therapeutics for Myopia

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Drugs for Myopia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 171)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
NepafenacapprovedPhase 43978281-72-8151075
Synonyms:
2-amino-3-Benzoylbenzeneacetamide
AHR 9434
AHR-9434
AL 6515
 
AL-6515
Amfenac amide
Ilevro
Nepafenaco
Nepafenacum
Nevanac
2
DipivefrinapprovedPhase 48452365-63-63105
Synonyms:
( -)-2,2-Dimethylpropansaeure-4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylenester
( -)-4-(1-Hydroxy-2-methylaminoethyl)-o-phenylendipivalat
(+-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol 3,4-dipivalate
(+-)-4-[1-Hydroxy-2-(methylamino)ethyl]-O-phenylene divavalate
(+-)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
(RS)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylen dipivalat
1-(3',4'-Dipivaloyloxyphenyl)-2-methylamino-1-ethanol
1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol
2,2-Dimethylpropanoic acid 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylen dipivalat
4-[1-Hydroxy-2-(methylamino)ethyl]-O-phenylene divavalate
4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate)
52365-63-6
AB00514686
AC1L1F6K
AKOS003662293
AKPro
BPBio1_000688
BRD-A47494775-003-03-0
BSPBio_000624
C06963
C19H29NO5
CHEBI:4646
CID3105
D02349
DB00449
Dipivalyl Epinephrine
 
Dipivefrin
Dipivefrin (USAN)
Dipivefrin HCL
Dipivefrin Hydrochloride
Dipivefrin [USAN]
Dipivefrina
Dipivefrina [INN-Spanish]
Dipivefrine
Dipivefrine (INN)
Dipivefrinum
Dipivefrinum [INN-Latin]
Dipivéfrine
K 30081
L000915
LS-121419
NCGC00179499-01
Ophtho-Dipivefrin
Prestwick0_000632
Prestwick1_000632
Prestwick2_000632
Prestwick3_000632
Pro-Epinephrine
Propine
Propine C Cap B.I.D.
SPBio_002843
UNII-8Q1PVL543G
[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate
dipivalyl epinephrine
dipivefrin
nchembio747-comp3
3
KetorolacapprovedPhase 427866635-83-43826
Synonyms:
(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(+-)-Ketorolac
(+-)-isomer
(.+/-.)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
66635-83-4
74103-06-3
AB00053682
AC-545
AC1L1GSW
Acular
Acuvail
BRD-A40639672-234-05-7
C07062
CHEBI:105080
CHEMBL469
CID3826
D020910
D08104
DB00465
 
I14-2832
Ketoralac
Ketorolac
Ketorolac (INN)
Ketorolac Tromethamine
Ketorolac [INN:BAN]
Ketorolaco
Ketorolaco [Spanish]
Ketorolacum
Ketorolacum [Latin]
Kétorolac
LS-139094
Macril
MolPort-005-933-093
NCGC00185990-01
RS 37619
RS-37619
SBB067312
STL018674
Sprix
Toradol (TN)
UNII-YZI5105V0L
ketorolac
rac-Ketorolac
4
AtropineapprovedPhase 4, Phase 2, Phase 3, Phase 11155908-99-6, 51-55-8174174
Synonyms:
(+,-)-Tropyl tropate
(+-)-Atropine
(+-)-Hyoscyamine
(+-)-atropine
(+-)-hyoscyamine
(+/-)-Atropine
(+/-)-Hyoscyamine
(3-Endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
(3-endo)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
(3-endo,8-syn)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-azoniabicyclo[3.2.1]octane
(3-exo)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
(±)-atropine
(±)-hyoscyamine
1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester)
1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester) (8CI)
120-29-6
1alphaH,5alphaH-Tropan-3alpha-ol
1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate (ester)
1alphaH,5alphaH-Tropan-3beta-ol
2-Phenylhydracrylic acid 3-alpha-tropanyl ester
51-55-8
8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate
8-Methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropionate
A0132_SIGMA
A2468_SIGMA
AC1L5AX3
AC1Q3XL2
ACon1_000046
AI3-60219
AKOS005137976
ATROPINE
Ambap120-29-6
Anaspaz
Atropair
Atropen
Atropen (TN)
Atropin
Atropin [German]
Atropin-flexiolen
Atropina
Atropina [Italian]
Atropine
Atropine (USP)
Atropine Care
Atropine Sulfate
Atropine Sulfate S.O.P.
Atropine [BAN]
Atropinol
Atropinum
Atropt
Atrosulf
BRD-A27290375-001-01-8
Belladenal
Bellergal-S
Benzeneacetic acid, alpha-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
C01479
C17H23NO3
CAS-120-29-6
CCRIS 3080
CHEBI:15742
CHEBI:15884
CHEBI:16684
CHEBI:537621
CHEBI:57858
CHEMBL1235490
 
CID174174
CPD001906768
Cytospaz
D00113
DB00572
DB04026
DL-Hyoscyamine
DL-Tropanyl 2-hydroxy-1-phenylpropionate
DL-Tropyl tropate
EINECS 200-104-8
Eyesules
FT-0082634
HMS2089A16
HSDB 2199
Hyoscyamine sulfate
I-Tropine
Isopto Atropine
Isopto-atropine
LS-7203
MEGxp0_001878
MLS000069795
MLS001148094
MLS002695888
Minims
Minims Atropine
MolPort-001-742-593
MolPort-003-986-158
Mydriasine
NCGC00016370-01
NCGC00142514-01
NCGC00142514-03
NP-010662
Neo-Diophen
OR22908
Ocu-Tropine
Protamine & Atropine
SAM002554885
SMR000058248
ST057178
ST057655
T0534
TL8000018
Tropanol
Tropic acid, 3-alpha-tropanyl ester
Tropic acid, ester with tropine
Tropine (+/-)-tropate
Tropine tropate
Tropine, tropate (ester)
Troyl tropate
Urised
[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate
[(1S,5R)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-hydroxy-2-phenyl-propanoate
[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-hydroxy-2-phenyl-propanoate
a-Tropine
atropinium cation
atropinium(1+)
b eta-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
beta-Phenyl-gamma-oxypropionsaeure-tropyl-ester [German]
beta-Phenyl-gamma-oxypropionsaure-tropyl-ester [German]
bmse000649
d1-hyoscyamine
dl-Hyoscyamine
dl-Tropyltropate
dl-tropyltropate
endo-(+/-)-alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
endo-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
hyoscyamine
nchembio.307-comp21
tropan-3alpha-ol
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate
tropan-3beta-ol
5
Verteporfinapproved, investigationalPhase 4, Phase 3, Phase 183129497-78-55362420
Synonyms:
Verteporfin
Verteporfina
 
Verteporfinum
Vertéporfine
Visudyne
6
RanibizumabapprovedPhase 4, Phase 3, Phase 2, Phase 1460347396-82-1459903
Synonyms:
347396-82-1
D05697
Lucentis
Lucentis (TN)
 
Ranibizumab
Ranibizumab (USAN/INN)
Ranibizumab (genetical recombination)
Ranibizumab (genetical recombination) (JAN)
ranibizumab
rhuFab V2
7
Bevacizumabapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 11875216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
8
TropicamideapprovedPhase 4, Phase 2211508-75-45593
Synonyms:
(+-)-N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide
1508-75-4
5-22-09-00359 (Beilstein Handbook Reference)
AB00052120
AC-816
AC1L1KOZ
AC1Q5IFA
AR-1K6980
Akorn Brand of Tropicamide
Alcon Brand of Tropicamide
BPBio1_000303
BRD-A79672927-001-05-8
BRN 0285563
BSPBio_000275
BSPBio_002289
Bio-0810
Bistropamide
Bournonville Brand of Tropicamide
CHEMBL1200604
CID5593
CPD000058523
Cahill May Roberts Brand of Tropicamide
Chauvin Brand of Tropicamide
Colircusi Tropicamida
D00397
D014331
DB00809
DivK1c_000448
EINECS 216-140-2
EU-0101223
Epitromina
HMS1568N17
HMS1921I09
HMS2089M05
HMS2092A18
HMS501G10
I-Picamide
I06-0811
IDI1_000448
KBio1_000448
KBio2_001064
KBio2_003632
KBio2_006200
KBio3_001509
KBioGR_000873
KBioSS_001064
L001262
LS-28545
Lopac0_001223
MLS001306442
MLS002154240
Medical Ophthalmics Brand of Tropicamide
Minims tropicamide
MolPort-000-159-321
Mydral
Mydriacyl
Mydriacyl (TN)
Mydriafair
Mydriaticum
Mydrum
N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide
N-Ethyl-2-phenyl-N-4-[-pyridyl-methyl]hydracrylamide
N-Ethyl-N-(4-pyridylmethyl)tropamid
N-Ethyl-N-(4-pyridylmethyl)tropamide
N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide
N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
NCGC00016065-03
NCGC00016065-08
 
NCGC00024866-02
NCGC00024866-03
NCGC00024866-04
NCGC00024866-05
NCGC00024866-06
NINDS_000448
Novartis Brand of Tropicamide
Ocu Tropic
Ocu-Tropic
OcuTropic
Ocumed Brand of Tropicamide
Ocusoft Brand of Tropicamide
Opticyl
Paremyd
Pharmafair Brand of Tropicamide
Prestwick0_000228
Prestwick1_000228
Prestwick2_000228
Prestwick3_000228
Prestwick_487
Rivex Brand of Tropicamide
Ro 1-7683
SAM002564235
SMP1_000304
SMR000058523
SPBio_000872
SPBio_002196
SPECTRUM1500599
STK934612
Spectro-Cyl
Spectrum2_000936
Spectrum3_000655
Spectrum4_000377
Spectrum5_001585
Spectrum_000584
Stulln Brand 1 of Tropicamide
Stulln Brand 2 of Tropicamide
T 9778
T9778_SIGMA
TL8001101
Triaminic DM
Tropicacyl
Tropicamid
Tropicamida
Tropicamida [INN-Spanish]
Tropicamide
Tropicamide (JP15/USP/INN)
Tropicamide Alcon Brand
Tropicamide Chauvin Brand
Tropicamide Faure
Tropicamide Minims
Tropicamide Monofree
Tropicamide Monohydrochloride, (R)-Isomer
Tropicamide Monohydrochloride, (S)-Isomer
Tropicamide Novartis Brand
Tropicamide Ocumed Brand
Tropicamide Pharmafair Brand
Tropicamide Rivex Brand
Tropicamide [USAN:INN:BANJAN]
Tropicamide, (+-)-Isomer
Tropicamide, (R)-Isomer
Tropicamide, (S)-Isomer
Tropicamidum
Tropicamidum [INN-Latin]
Tropikamid
Tropimil
UNII-N0A3Z5XTC6
Visumidriatic
n-ethyl-n-(g-picolyl)tropamide
tropicamide
9
EchothiophateapprovedPhase 416736-03-410547, 10548
Synonyms:
(2-Mercaptoethyl)trimethylammonium iodide S-ester with O,O-diethyl phosphorothioate
(2-mercaptoethyl)trimethylammonium iodidie O,O-diethyl phosphorothioate
2-((Diethoxyphosphinyl)thio)-N,N,N,-trimethylethanaminium iodide
2-(Diethoxyphosphorylsulfanyl)ethyl-N,N,N-trimethylazanium iodide
2-Diaethoxyphosphinyl-thioaethyl-trimethyl-ammonium-jodid
2-Diaethoxyphosphinyl-thioaethyl-trimethyl-ammonium-jodid [German]
2-Diethoxy-phosphinylthioethyl-trimethylammonium iodide
2-[(diethoxyphosphinyl)thio]-N,N,N-trimethylethanaminium iodide
2-[(diethoxyphosphoryl)sulfanyl]-N,N,N-trimethylethanaminium iodide
2-diethoxyphosphorylsulfanylethyl(trimethyl)azanium iodide
2-{[bis(ethyloxy)phosphoryl]thio}-N,N,N-trimethylethanaminium iodide
217 MI
217-mi
513-10-0
AC1L1VFJ
AC1Q1TM0
Ammonium, (2-(O,O-diethylphosphorothio)ethyl)trimethyl-, iodide
Ammonium, (2-mercaptoethyl)trimethyl-, iodide, S-ester with O,O-diethylphosphorothioate
C9H22NO3PS
CHEBI:59849
CHEMBL1200367
CID10547
D004456
D02193
DB01057
Diethoxyphosphoryl-thiocholine iodide
ECOTHIOPATE IODIDE
EINECS 208-152-1
Echodide
Echothiophate
Echothiophate Iodide
Echothiophate iodide
 
Echothiophate iodide (USP)
Ecostigmini jodidum
Ecothiopate Iodide
Ecothiopate iodide (JP15/INN)
Ecothiopati iodidum
Ecothiopati iodidum [INN-Latin]
Ecothiopatum
Ecothiophate iodide
Ethanaminium, 2-((diethoxyphosphinyl)thio)-N,N,N-trimethyl-, iodide
Iodide, Echothiophate
Iodide, Ecothiopate
Iodide, Ecothiophate
Iodide, Phospholine
Iodure d'ecothiopate
Iodure d'ecothiopate [INN-French]
Ioduro de ecotiopato
Ioduro de ecotiopato [INN-Spanish]
LS-18625
MolPort-005-941-436
N-(2-(Diethoxyphosphinylthio)ethyl)trimethylammonium iodide
O,O-Diethyl S-2-trimethylammonium ethylphosphonothiolate iodide
Phospholine
Phospholine (the pharmaceutical)
Phospholine Iodide
Phospholine iodide
Phospholine iodide (TN)
S-(2-(N,N,N-Trimethylammonio)ethyl) O,O-diethylphosphorothiolate iodide
S-(2-Dimethylaminoethyl)-O.O-diethylphosphorothioate methiodide
S-(2-dimethylaminoethyl)-O,O-diethylphosphorothioate methiodide
S-Ester of (2-mercaptoethyl)trimethylammonium iodide with O,O-diethyl phosphorothioate
S-beta-dimethylaminoethyl-O,O-diethylthionophosphate methiodide
UNII-BA9QH3P00T
diethoxyphosphinylthiocholine iodide
10
Bromfenacapproved, Approved July 1997Phase 44191714-94-260726
Synonyms:
2-Amino-3-(4-bromobenzoyl)benzeneacetic acid
2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
2-amino-3-(4-Bromobenzoyl)benzeneacetic acid
91714-94-2
AC1L1TSW
AC1Q5DQ7
AHR-10282
Ambap120638-55-3
BROMFENAC SODIUM
Bromday
Bromfenac
Bromfenac (INN)
Bromfenac [INN]
Bromfenac sodium
Bromfenaco
Bromfenaco [Spanish]
 
Bromfenacum
Bromfenacum [Latin]
C15H12BrNO3
CHEBI:240107
CHEMBL1077
CID60726
D07541
DB00963
Duract
LS-178156
MolPort-000-883-091
Prolensa
UNII-864P0921DW
Xibrom
[2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
sodium 2-amino-3-(4-bromobenzoyl) phenylacetate sesquihydrate
{2-amino-3-[(4-bromophenyl)carbonyl]phenyl}acetic acid
11Dermatologic AgentsPhase 4, Phase 3, Phase 14555
12Immunologic FactorsPhase 4, Phase 3, Phase 2, Phase 118483
13Photosensitizing AgentsPhase 4, Phase 3, Phase 1374
14Respiratory System AgentsPhase 4, Phase 3, Phase 2, Phase 13931
15Angiogenesis Modulating AgentsPhase 4, Phase 3, Phase 2, Phase 13611
16MydriaticsPhase 4, Phase 2, Phase 3, Phase 1, Phase 0525
17Neurotransmitter AgentsPhase 4, Phase 2, Phase 3, Phase 114795
18ParasympatholyticsPhase 4, Phase 2, Phase 3, Phase 1902
19Muscarinic AntagonistsPhase 4, Phase 2, Phase 3, Phase 1961
20Anti-Infective AgentsPhase 4, Phase 2, Phase 117220
21MicronutrientsPhase 4, Phase 1, Phase 23901
22Trace ElementsPhase 4, Phase 1, Phase 23900
23Alkylating AgentsPhase 4, Phase 13582
24Gastrointestinal AgentsPhase 4, Phase 1, Phase 26401
25Anti-Infective Agents, LocalPhase 4, Phase 2984
26Cholinergic AntagonistsPhase 4, Phase 2, Phase 3, Phase 11423
27DisinfectantsPhase 4405
28
Hydrogen peroxidePhase 4467722-84-1784
Synonyms:
Adeka Super EL
Albone
Albone 35
Albone DS
Anti-Keim 50
Asepticper
Baquashock
CIX
Clarigel Gold
Crestal Whitestrips
Crystacide
Dentasept
Deslime LP
Hioxyl
Hipox
Hybrite
Hydrogen dioxide
Hydrogen peroxide
Inhibine
Lase Peroxide
Lensan A
 
Magic Bleaching
Metrokur
Mirasept
Nite White Excel 2
Odosat D
Opalescence Xtra
Oxigenal
Oxydol
Oxyfull
Oxysept
Oxysept I
Pegasyl
Perhydrol
Perone
Peroxaan
Peroxclean
Quasar Brite
Select Bleach
Superoxol
T-Stuff
Whiteness HP
Whitespeed
Xtra White
29Anti-Bacterial AgentsPhase 4, Phase 1, Phase 29140
30Antibiotics, AntitubercularPhase 4, Phase 1, Phase 25971
31Antirheumatic AgentsPhase 4, Phase 38496
32Angiogenesis InhibitorsPhase 4, Phase 3, Phase 2, Phase 13688
33Ophthalmic SolutionsPhase 4, Phase 2, Phase 3, Phase 11006
34Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 118510
35Cholinergic AgentsPhase 4, Phase 2, Phase 3, Phase 13243
36Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 1, Phase 28478
37Pharmaceutical SolutionsPhase 4, Phase 3, Phase 1, Phase 27004
38AnalgesicsPhase 4, Phase 39358
39Analgesics, Non-NarcoticPhase 4, Phase 35184
40TetrahydrozolinePhase 4, Phase 2, Phase 3, Phase 1542
41Anti-Inflammatory Agents, Non-SteroidalPhase 43549
42Anti-Asthmatic AgentsPhase 4, Phase 2, Phase 3, Phase 12796
43MitomycinsPhase 4, Phase 1219
44Lubricant Eye DropsPhase 4153
45Bronchodilator AgentsPhase 4, Phase 2, Phase 3, Phase 12377
46Anti-Arrhythmia AgentsPhase 4, Phase 2, Phase 3, Phase 12371
47AnestheticsPhase 4, Phase 2, Phase 3, Phase 17385
48Ketorolac TromethaminePhase 4278
49Nucleic Acid Synthesis InhibitorsPhase 4, Phase 13836
50Cyclooxygenase InhibitorsPhase 42225

Interventional clinical trials:

(show top 50)    (show all 491)
idNameStatusNCT IDPhase
1Evaluation of the Prophylactic Use of Mitomycin C 0.02% to Inhibit Haze Formation After Photorefractive Keratectomy for High Myopia: 15 x 30 SecondsCompletedNCT00564213Phase 4
2Visual Outcomes and Contrast Sensitivity After Myopic LASIKCompletedNCT01746589Phase 4
3Bevacizumab Intravitreal for Myopic Choroidal NeovascularizationCompletedNCT00797992Phase 4
4A Comparison of PRK and LASIK for Correction of MyopiaCompletedNCT00404105Phase 4
5An Evaluation of Outcomes Following Wavefront Optimized or Wavefront Guided Lasik Procedure in Low to Moderate Myopic PatientsCompletedNCT01173198Phase 4
6Presbyopic Supracor Treatment for Near Myopic/Hyperopic Pseudophakic EyesCompletedNCT01387360Phase 4
7Evaluation of the Post-LASIK Flap Thickness of the FS200 Femtosecond Laser FlapCompletedNCT01693939Phase 4
8Contralateral Comparison of Three Excimer Laser Systems in Performing LASIKCompletedNCT00821236Phase 4
9Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens ExtractionCompletedNCT01225952Phase 4
10Daily Wear Corneal Infiltrative Event StudyCompletedNCT00937105Phase 4
11Overall Performance of a 1-day Silicone Hydrogel Lens When Habitual Soft Lens Wearers Are RefitCompletedNCT02588573Phase 4
12The Clinical Performance of the Biofinity Contact Lens (Comfilcon A) With Two Lens Care SystemsCompletedNCT02510820Phase 4
13Clinical Performance of Hydrogel vs. Silicone Hydrogel Contact LensesCompletedNCT02131402Phase 4
14Clinical Evaluation of Daily Disposable Contact LensesCompletedNCT02097030Phase 4
15Daily Disposable Comparison StudyCompletedNCT02094677Phase 4
16Multi-center Clinical Evaluation of PC 1-Day vs 1-Day Acuvue MoistCompletedNCT02024698Phase 4
17Evaluation of Stenfilcon A Versus Etafilcon ACompletedNCT01809834Phase 4
18Clinical Performance of Stenfilcon A Versus Filcon II 3CompletedNCT01808209Phase 4
19Multi-Centre Clinical Evaluation Of Two Daily Disposable Contact LensesCompletedNCT01707238Phase 4
20Evaluation of Comfilcon A and Senofilcon A LensesCompletedNCT01695369Phase 4
21Bromday Versus Nevanac Eye Drops to Control Pain Following Photorefractive KeratectomyCompletedNCT01475877Phase 4
22Effect of Preoperative Pupil Size on Quality of Vision After Wavefront-Guided LASIKCompletedNCT00889941Phase 4
23Comparative Performance of PureVision, Acuvue Oasys and O2OptixCompletedNCT00640341Phase 4
24Efficacy of PEG-400 and Systane Artificial Tears (Alcon) on Quality of VisionCompletedNCT00627302Phase 4
25Corneal and Conjunctival Sensitivity and Staining StudyCompletedNCT00455455Phase 4
26Long-term Effects of Laser Refractive SurgeryCompletedNCT00350246Phase 4
27Effects of Contact Lens Care Regimens on the Corneal EpitheliumCompletedNCT00349882Phase 4
28Investigation of Multi-Purpose Solution-Based Corneal Staining and Ocular ComfortCompletedNCT00349843Phase 4
29Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRKCompletedNCT00347204Phase 4
30Visual Performance After RESTOR ImplantationCompletedNCT01065064Phase 4
31Bilateral, Masked Comparison of PEG-400 Based Artificial Tear vs. Systane for Dry Eye Signs, Symptoms & Refractive Regression Associated With Myopic Laser in Situ Keratomilieusis (LASIK).CompletedNCT00620893Phase 4
32Evaluation of 3 Intraocular Lenses Following Lens ExtractionCompletedNCT01122576Phase 4
33PreView PHP Preferential Hyperacuity Perimeter for the Detection of Choroidal NeovascularizationCompletedNCT00358345Phase 4
34Clinical Evaluation of Biofinity Multifocal Compared With Air Optix Aqua Multifocal and With PureVision MultifocalCompletedNCT01591499Phase 4
35Clinical Evaluation of the One-Piece Tecnis Multifocal Intraocular Lens (IOL)CompletedNCT01210807Phase 4
36Comparison of Visual Outcomes and Patient Satisfaction After Cataract Surgery and Implantation of ReSTOR and ReZoom IOLsCompletedNCT00366587Phase 4
37Effect of Orthokeratology Versus Spectacles on Myopia Progression in Chinese Children: A Crossover TrialRecruitingNCT02186184Phase 4
38Study of Myopia Prevention in Children With Low Concentration of AtropineRecruitingNCT00541177Phase 4
39A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser in Asian Eyes Using LASIKRecruitingNCT01977807Phase 4
40Aflibercept Intravitreal Injection for Myopic Choroidal NeovascularizationRecruitingNCT02033018Phase 4
41Wavefront-guided PRK vs Wavefront-optimized PRKRecruitingNCT02091934Phase 4
42A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser Using LASIKRecruitingNCT02071576Phase 4
43High Resolution Wavefront-guided vs. Wavefront Optimized LASIKRecruitingNCT02565537Phase 4
44Cohort Study of the Clinical Course of Macular Diseases in KagawaRecruitingNCT02321267Phase 4
45Ranibizumab for Myopic NeovascularizationActive, not recruitingNCT01246089Phase 4
46Efficacy and Safety of MiSight ® Contact Lenses in Reducing the Progression of Childhood Myopia.Active, not recruitingNCT01917110Phase 4
47Wavefront-guided Photorefractive Keratectomy (PRK) Versus Wavefront-guided Lasik for MyopiaActive, not recruitingNCT01140594Phase 4
48LASIK Using the Alcon Allegretto Wavefront-Guided Excimer Laser vs AMO Visx Wavefront-Guided Excimer LaserActive, not recruitingNCT01454843Phase 4
49Multi Laser Platform Comparison Study for LASIKActive, not recruitingNCT00770094Phase 4
50Post Photorefractive Keratectomy (PRK) Use of an Eye Shield for Maintaining Vision and Mitigating PainActive, not recruitingNCT01592643Phase 4

Search NIH Clinical Center for Myopia


Cochrane evidence based reviews: myopia

Genetic Tests for Myopia

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Anatomical Context for Myopia

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MalaCards organs/tissues related to Myopia:

33
Eye, Retina, Heart, Endothelial, Liver, Bone, Brain

Animal Models for Myopia or affiliated genes

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MGI Mouse Phenotypes related to Myopia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.0COL18A1, COL2A1, FMOD, LAMA1, NYX, OPN1LW
2MP:00036317.9CLDN19, COL11A1, COL18A1, COL2A1, COL9A2, FBN1
3MP:00053867.6CLDN19, COL2A1, COL9A2, FBN1, FMOD, LAMA1

Publications for Myopia

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Articles related to Myopia:

(show top 50)    (show all 963)
idTitleAuthorsYear
1
Spontaneous resolution of foveal detachment in traction maculopathy in high myopia unrelated to posterior vitreous detachment. (26868376)
2016
2
Myopia Control: A Review. (26513719)
2015
3
Myopia and/or longer axial length are protective against diabetic retinopathy: a meta-analysis. (26547796)
2015
4
Macular parameters of Stratus optical coherence tomography for assessing glaucoma in high myopia. (25349103)
2014
5
Correlation between central corneal thickness and myopia in Taiwan. (24388054)
2014
6
Comparative Evaluation of Higher-Order Aberrations and Corneal Asphericity Between Wavefront-guided and Aspheric LASIK for Myopia. (25375851)
2014
7
Generational difference of refractive error and risk factors in the Handan Offspring Myopia Study. (25097244)
2014
8
Association of Lumican gene polymorphism with high myopia: a meta-analysis. (24061151)
2013
9
Co-existent choroidal neovascular membrane and macular hole in pathologic myopia: a long follow-up clinical outcome and literature review. (24392342)
2013
10
Retinal nerve fiber layer in primary open-angle glaucoma with high myopia determined by optical coherence tomography and scanning laser polarimetry. (23595371)
2013
11
Peripheral defocus and myopia progression in myopic children randomly assigned to wear single vision and progressive addition lenses. (23838771)
2013
12
Clear lens phacoemulsification combined with vitrectomy to correct high myopia: four years of follow-up. (23257681)
2013
13
Effect of myopia and age on optic disc margin anatomy within the parapapillary atrophy area. (23851575)
2013
14
Heritability of myopia and ocular biometrics in Koreans: the healthy twin study. (23620424)
2013
15
The effect of the Chinese Cultural Revolution and Great Leap Forward on the prevalence of myopia. (24197389)
2013
16
Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. (23933737)
2013
17
Aqueous Concentrations of Vascular Endothelial Growth Factor in Eyes with High Myopia with and without Choroidal Neovascularization. (23533702)
2013
18
A contralateral, randomized comparison of optimized prolate ablation and conventional LASIK for myopia with the NIDEK excimer laser platform. (22767164)
2012
19
Baseline characteristics of nearwork-induced transient myopia. (23187872)
2012
20
The impact of parental myopia on myopia in Chinese children: population-based evidence. (22922777)
2012
21
Atropine for the treatment of childhood myopia: safety and efficacy of 0.5%, 0.1%, and 0.01% doses (Atropine for the Treatment of Myopia 2). (21963266)
2012
22
Ten SNPs of PAX6, Lumican, and MYOC genes are not associated with high myopia in Han Chinese. (22809227)
2012
23
High myopia as a risk factor in primary open angle glaucoma. (23275912)
2012
24
On the dangers of methodolatry, moral hazard and myopia in research. (22176663)
2012
25
Acquired optic nerve and peripapillary pits in pathologic myopia. (22494632)
2012
26
Prevalence of myopia in a population with malocclusions. (23046255)
2012
27
Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. (21095009)
2011
28
Nature and nurture: the complex genetics of myopia and refractive error. (21155761)
2011
29
A functional polymorphism at 3'UTR of the PAX6 gene may confer risk for extreme myopia in the Chinese. (21421876)
2011
30
Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population. (21640322)
2011
31
Pigmented free-floating vitreous cyst in a patient with high myopia and uveal coloboma simulating choroidal melanoma. (21485975)
2011
32
Age-related changes of phoria myopia in patients with intermittent exotropia. (19184303)
2009
33
Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. (19836009)
2009
34
Myocilin polymorphisms and high myopia in subjects of European origin. (19180258)
2009
35
Linkage analysis of high myopia susceptibility locus in 26 families. (19122830)
2008
36
Prevalence of myopia and hyperopia among urban and rural schoolchildren in Poland. (19127805)
2008
37
Pupillography of relative afferent pupillary defects in amblyopia associated with peripapillary myelinated nerve fibers and myopia. (18825905)
2008
38
Active cyclotorsion error correction during LASIK for myopia and myopic astigmatism with the NIDEK EC-5000 CX III laser. (18047004)
2007
39
Evidence for delayed presbyopia after photorefractive keratectomy for myopia. (16650666)
2006
40
The role of the retinal pigment epithelium in eye growth regulation and myopia: a review. (16079001)
2005
41
X-linked high myopia associated with cone dysfunction. (15197065)
2004
42
Fixation linked hypotropia in high myopia. A report of two similar cases. (12597767)
2003
43
Myopia and models and mechanisms of refractive error control. (12064076)
2002
44
Volume estimation of excimer laser tissue ablation for correction of spherical myopia and hyperopia. (11980859)
2002
45
Intraocular lens implantation and laser in situ keratomileusis (bioptics) to correct high myopia and hyperopia with astigmatism. (11316030)
2001
46
Clinical features and surgery for acquired progressive esotropia associated with severe myopia. (10071152)
1999
47
A second locus for familial high myopia maps to chromosome 12q. (9792869)
1998
48
Prolidase deficiency associated with pathologic myopia. (9587929)
1998
49
Flicker parameters are different for suppression of myopia and hyperopia. (9373666)
1997
50

Variations for Myopia

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Expression for genes affiliated with Myopia

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Search GEO for disease gene expression data for Myopia.

Pathways for genes affiliated with Myopia

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GO Terms for genes affiliated with Myopia

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Biological processes related to Myopia according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1proteoglycan metabolic processGO:000602910.6COL11A1, COL2A1
2cartilage condensationGO:000150210.6COL11A1, COL2A1
3collagen fibril organizationGO:003019910.1COL11A1, COL2A1, FMOD
4collagen catabolic processGO:00305749.9COL11A1, COL18A1, COL2A1
5sensory perception of soundGO:00076059.9COL11A1, COL2A1, SLITRK6
6visual perceptionGO:00076019.3COL11A1, COL18A1, OPN1LW, SLITRK6
7extracellular matrix disassemblyGO:00226179.0COL11A1, COL18A1, COL2A1, COL9A2, FBN1

Sources for Myopia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet