MCID: MYP006
MIFTS: 41

Myopia malady

Eye diseases category

Summaries for Myopia

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32MalaCards
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MalaCards: Myopia, also known as near-sightedness, is related to myopia 6 and astigmatism. An important gene associated with Myopia is NYX (nyctalopin). Affiliated tissues include eye, endothelial and retina.

Aliases & Classifications for Myopia

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

myopia 8 60
near-sightedness 8
near vision 8


External Ids:

Disease Ontology8 DOID:11830
MeSH34 D009216
SNOMED-CT56 155133003, 57190000
ICD9CM27 367.1

Related Diseases for Myopia

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Myopia 6 family:

myopia Myopia 14
Myopia 12 Myopia 8
Myopia 9 Myopia 11
Myopia 16 Myopia 19
Myopia 17 Myopia 10
Myopia 15 Myopia 7
Myopia-3 Myopia 18
Myopia 5 Myopia-2
Myopia 13 Myopia-1

Diseases related to Myopia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 286)
idRelated DiseaseScoreTop Affiliating Genes
1myopia 630.4NYX, ZNF644, FMOD
2astigmatism10.6
3choroiditis10.6
4retinitis10.6
5refractive error10.5
6degenerative myopia10.5
7glaucoma10.5
8cataract10.4
9polydactyly myopia syndrome10.3
10macular holes10.3
11open-angle glaucoma10.3
12esotropia10.3
13retinal detachment10.3
14amblyopia10.3
15primary open angle glaucoma10.2
16blepharoptosis myopia ectopia lentis10.2
17anisometropia10.2
18congenital stationary night blindness10.2
19night blindness10.2
20strabismus10.2
21presbyopia10.2
22coloboma10.1
23retinoschisis10.1
24x-linked congenital stationary night blindness10.1
25aplasia cutis myopia10.1
26sinus node disease and myopia10.1
27aniseikonia10.1
28corneal ectasia10.1
29donnai-barrow syndrome10.1
30dandy-walker malformation with mental retardation, macrocephaly, myopia and brachytelephalangy10.1
31myopia 22, autosomal dominant10.1
32gyrate atrophy10.1
33exotropia10.1
34eye disease10.1
35keratoconus10.1
36optic atrophy10.1
37myopia 21, autosomal dominant10.1
38epiphyseal dysplasia, multiple, with myopia and deafness10.1
39facial dysmorphism - macrocephaly - myopia - dandy-walker malformation10.1
40x-linked cone dysfunction syndrome with myopia10.1
41retinopathy of prematurity10.0
42chorioretinitis10.0
43corneal dystrophy10.0
44retinal degeneration10.0
45scleritis10.0
46cohen syndrome10.0
47anophthalmia or microphthalmia, retinal dystrophy and/or myopia associated with brain anomalies10.0
48stickler syndrome type 110.0
49noble bass sherman syndrome10.0
50optic atrophy opthalmoplegia ptosis deafness myopia10.0

Graphical network of the top 20 diseases related to Myopia:



Diseases related to myopia

Clinical Features for Myopia

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Drugs & Therapeutics for Myopia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Myopia

Drug clinical trials:

Search ClinicalTrials for Myopia

Search NIH Clinical Center for Myopia

Search CenterWatch for Myopia

Genetic Tests for Myopia

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Anatomical Context for Myopia

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32MalaCards
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MalaCards organs/tissues related to Myopia:

32
Eye, Endothelial, Retina, Testes, Heart, Cortex

Animal Models for Myopia or affiliated genes

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Publications for Myopia

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Sources:
50PubMed
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Articles related to Myopia:

(show top 50)    (show all 837)
idTitleAuthorsYear
1
Integration of Defocus by Dual Power Fresnel Lenses Inhibits Myopia in the Mammalian Eye. (24398103)
2014
2
Vascular endothelial growth factor gene and the response to anti-vascular endothelial growth factor treatment for choroidal neovascularization in high myopia. (23953100)
2014
3
Comparison of visual acuity, higher-order aberrations and corneal asphericity after refractive lenticule extraction and wavefront-guided laser-assisted in situ keratomileusis for myopia. (23269682)
2013
4
Distinct ocular expression in infants and children with Down syndrome in Cairo, Egypt: myopia and heart disease. (23764677)
2013
5
Epigenetic Regulation of I+A-crystallin in High Myopia-Induced Dark Nuclear Cataract. (24312600)
2013
6
Mutations in LRPAP1 are associated with severe myopia in humans. (23830514)
2013
7
Influence of periodic vs continuous daily bright light exposure on development of experimental myopia in the chick. (23668224)
2013
8
Myopia control using toric orthokeratology (TO-SEE study). (24003088)
2013
9
Differential associations of myopia with major age-related eye diseases: the Singapore Indian Eye Study. (23084122)
2013
10
Myopia and age-related cataract: a systematic review and meta-analysis. (23938120)
2013
11
A characteristic optic disc appearance associated with myopia in subjects with Graves' ophthalmopathy and in subjects with primary open-angle glaucoma. (23326183)
2013
12
Association study of fibroblast growth factor 10 (FGF10) polymorphisms with susceptibility to extreme myopia in a Japanese population. (24265547)
2013
13
Focusing in on the complex genetics of myopia. (23593034)
2013
14
Correction of High Myopia with Foldable Artiflex Phakic Intraocular Lenses: 1 Year Follow-up Results. (24338193)
2013
15
Is myopia a failure of homeostasis? (23454097)
2013
16
High myopia as a risk factor in primary open angle glaucoma. (23275912)
2012
17
A retrospective analysis of the first Yemeni experience on Artisan phakic intraocular lens for the treatment of moderate and high myopia. (23439933)
2012
18
Myopia progression in Chinese children is slower in summer than in winter. (22797511)
2012
19
Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility. (22539872)
2012
20
Photorefractive keratectomy with mitomycin-C for the combined treatment of myopia and subepithelial infiltrates after epidemic keratoconjunctivitis. (22624902)
2012
21
Corneal higher order aberrations after LASIK for high myopia with a fast repetition rate excimer laser, optimized ablation profile, and femtosecond laser-assisted flap. (23061998)
2012
22
Acupuncture for slowing the progression of myopia in children and adolescents. (21901710)
2011
23
Assessment of exonic single nucleotide polymorphisms in the adenosine A2A receptor gene to high myopia susceptibility in Chinese subjects. (22740769)
2011
24
Efficacy of primary silicone oil tamponade for the treatment of retinal detachment caused by macular hole in high myopia. (21130979)
2011
25
Polymorphisms in steroidogenesis genes, sex steroid levels, and high myopia in the Taiwanese population. (21921981)
2011
26
Risk factors for hyperopia and myopia in preschool children the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. (21856013)
2011
27
Drug-induced myopia, hyperopia and accommodation disorders. (20738037)
2010
28
Absence of association between COL1A1 polymorphisms and high myopia in the Japanese population. (18836165)
2009
29
Corneal topography six years after photorefractive keratectomy for myopia and myopic astigmatism. (19507798)
2009
30
Association of PAX6 polymorphisms with high myopia in Han Chinese nuclear families. (19124844)
2009
31
A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1. (19779542)
2009
32
Inherited partial aniridia, microcornea with high myopia and Bergmeister's papilla: a new phenotypic expression. (18292626)
2008
33
Wavefront-guided LASIK for the correction of primary myopia and astigmatism a report by the American Academy of Ophthalmology. (18598819)
2008
34
A genome-wide scan maps a novel high myopia locus to 5p15. (18421076)
2008
35
Association between high myopia and progression of visual field loss in primary open-angle glaucoma. (19129056)
2008
36
Application of fluorescence difference gel electrophoresis technology in searching for protein biomarkers in chick myopia. (17924678)
2007
37
Analysis of single nucleotide polymorphisms at 13 loci within the transforming growth factor-induced factor gene shows no association with high myopia in Japanese subjects. (17048038)
2006
38
Identification of a novel locus on 2q for autosomal dominant high-grade myopia. (15980214)
2005
39
Fundamentals of modern treatment of myopia]. (16519089)
2005
40
Volume estimation of excimer laser tissue ablation for correction of spherical myopia and hyperopia. (11980859)
2002
41
Excessive myopia and anisometropia associated with familial exudative vitreoretinopathy. (12173668)
2002
42
A study on the prevention and treatment of myopia with nacre on chicks. (11428903)
2001
43
Laser in situ keratomileusis for myopia and hyperopia using the Lasersight 200 laser in 300 consecutive eyes. (11110312)
2000
44
Iatrogenic keratoconus: corneal ectasia following laser in situ keratomileusis for myopia. (10676799)
2000
45
High myopia, hypertelorism, iris coloboma, exomphalos, absent corpus callosum, and sensorineural deafness: report of a case and further evidence for autosomal recessive inheritance. (10794262)
2000
46
Autosomal dominant typical coloboma associated with unilateral pseudoptosis, myopia and cataract. (7585914)
1995
47
Refractive change in hyperglycaemia: hyperopia, not myopia. (7104266)
1982
48
Bullous keratopathy after anterior-posterior radial keratotomy for myopia for myopic astigmatism. (7081358)
1982
49
Stickler syndrome. Presenting as a syndrome of cleft palate, myopia and blindness inherited as a dominant trait. (4218495)
1974
50
Retinal changes in degenerative myopia. (13900972)
1962

Genetic Variations for Myopia

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Expression for genes affiliated with Myopia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myopia

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Pathways for genes affiliated with Myopia

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Compounds for genes affiliated with Myopia

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GO Terms for genes affiliated with Myopia

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16Gene Ontology
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Biological processes related to Myopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to stimulusGO:05089610.6NYX, CLDN19

Products for genes affiliated with Myopia

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  • Antibodies
  • Proteins
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Sources for Myopia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet