MCID: MYP006
MIFTS: 36

Myopia malady

Summaries for Myopia

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33MalaCards
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MalaCards: Myopia, also known as near-sightedness, is related to myopia 6 and astigmatism. An important gene associated with Myopia is NYX (nyctalopin).

Aliases & Classifications for Myopia

Sources:
8Disease Ontology, 61UMLS, 57SNOMED-CT, 35MeSH, 27ICD9CM
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Aliases & Descriptions:

myopia 8 61
near-sightedness 8
near vision 8


External Ids:

Disease Ontology8 DOID:11830
MeSH35 D009216
SNOMED-CT57 155133003, 57190000
ICD9CM27 367.1

Related Diseases for Myopia

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the myopia 6 family:

myopia myopia 14
myopia 12 myopia 8
myopia 9 myopia 11
myopia 16 myopia 19
myopia 17 myopia 10
myopia 15 myopia 7
myopia-3 myopia 18
myopia 5 myopia-2
myopia 13 myopia-1

Diseases related to Myopia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 274)
idRelated DiseaseScoreTop Affiliating Genes
1myopia 630.4NYX, ZNF644, FMOD
2astigmatism10.6
3hyperopia10.6
4degenerative myopia10.5
5myopia-110.4
6polydactyly myopia syndrome10.4
7myopia, autosomal10.4
8amblyopia10.3
9primary open angle glaucoma10.3
10blepharoptosis myopia ectopia lentis10.3
11blindness10.3
12anisometropia10.2
13congenital stationary night blindness10.2
14strabismus10.2
15myopia 1510.2
16presbyopia10.2
17aplasia cutis myopia10.2
18myopia 510.2
19coloboma10.2
20x-linked congenital stationary night blindness10.2
21sinus node disease and myopia10.2
22myopia 1910.2
23myopia-210.2
24aniseikonia10.2
25corneal ectasia10.1
26donnai-barrow syndrome10.1
27dandy-walker malformation with mental retardation, macrocephaly, myopia and brachytelephalangy10.1
28myopia 810.1
29myopia 22, autosomal dominant10.1
30myopia 1310.1
31gyrate atrophy10.1
32myopia, x-linked10.1
33myopia 21, autosomal dominant10.1
34myopia 1110.1
35myopia 1010.1
36myopia 710.1
37epiphyseal dysplasia, multiple, with myopia and deafness10.1
38myopia 1810.1
39facial dysmorphism - macrocephaly - myopia - dandy-walker malformation10.1
40x-linked cone dysfunction syndrome with myopia10.1
41cohen syndrome10.0
42anophthalmia or microphthalmia, retinal dystrophy and/or myopia associated with brain anomalies10.0
43stickler syndrome type 110.0
44noble bass sherman syndrome10.0
45optic atrophy opthalmoplegia ptosis deafness myopia10.0
46myopia 1210.0
47myopia, high, with cataract and vitreoretinal degeneration10.0
48myopia 910.0
49deafness and myopia10.0
50night blindness, congenital stationary , 1a, x-linked10.0

Graphical network of the top 20 diseases related to Myopia:



Diseases related to myopia

Clinical Features for Myopia

Drugs & Therapeutics for Myopia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Myopia

Drug clinical trials:

Search ClinicalTrials for Myopia

Search NIH Clinical Center for Myopia

Search CenterWatch for Myopia

Genetic Tests for Myopia

Anatomical Context for Myopia

Animal Models for Myopia or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Myopia

Sources:
51PubMed
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Articles related to Myopia:

(show top 50)    (show all 840)
idTitleAuthorsYear
1
Vascular endothelial growth factor gene and the response to anti-vascular endothelial growth factor treatment for choroidal neovascularization in high myopia. (23953100)
2014
2
Clear lens phacoemulsification combined with vitrectomy to correct high myopia: four years of follow-up. (23257681)
2013
3
Choroidal neovascularization following laser in situ keratomileusis for high myopia: a case series. (23076454)
2013
4
Effect of the combination of basic fibroblast growth factor and cysteine on corneal epithelial healing after photorefractive keratectomy in patients affected by myopia. (24145571)
2013
5
Contribution of TGFI^1 codon 10 polymorphism to high myopia in an ethnic Kashmiri population from India. (23325483)
2013
6
Epigenetic Regulation of I+A-crystallin in High Myopia-Induced Dark Nuclear Cataract. (24312600)
2013
7
Mutations in LRPAP1 are associated with severe myopia in humans. (23830514)
2013
8
Influence of periodic vs continuous daily bright light exposure on development of experimental myopia in the chick. (23668224)
2013
9
Myopia control using toric orthokeratology (TO-SEE study). (24003088)
2013
10
Differential associations of myopia with major age-related eye diseases: the Singapore Indian Eye Study. (23084122)
2013
11
Myopia and age-related cataract: a systematic review and meta-analysis. (23938120)
2013
12
A characteristic optic disc appearance associated with myopia in subjects with Graves' ophthalmopathy and in subjects with primary open-angle glaucoma. (23326183)
2013
13
Association study of fibroblast growth factor 10 (FGF10) polymorphisms with susceptibility to extreme myopia in a Japanese population. (24265547)
2013
14
Focusing in on the complex genetics of myopia. (23593034)
2013
15
Correction of High Myopia with Foldable Artiflex Phakic Intraocular Lenses: 1 Year Follow-up Results. (24338193)
2013
16
Is myopia a failure of homeostasis? (23454097)
2013
17
Annual changes in refractive errors and ocular components before and after the onset of myopia in Chinese children. (22578257)
2012
18
Phacomorphic intermittent angle closure in a patient with retinopathy of prematurity and lenticular high myopia. (22171987)
2012
19
Myopia progression in Chinese children is slower in summer than in winter. (22797511)
2012
20
Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility. (22539872)
2012
21
Photorefractive keratectomy with mitomycin-C for the combined treatment of myopia and subepithelial infiltrates after epidemic keratoconjunctivitis. (22624902)
2012
22
Corneal higher order aberrations after LASIK for high myopia with a fast repetition rate excimer laser, optimized ablation profile, and femtosecond laser-assisted flap. (23061998)
2012
23
Nature and nurture: the complex genetics of myopia and refractive error. (21155761)
2011
24
Acupuncture for slowing the progression of myopia in children and adolescents. (21901710)
2011
25
Assessment of exonic single nucleotide polymorphisms in the adenosine A2A receptor gene to high myopia susceptibility in Chinese subjects. (22740769)
2011
26
Efficacy of primary silicone oil tamponade for the treatment of retinal detachment caused by macular hole in high myopia. (21130979)
2011
27
Polymorphisms in steroidogenesis genes, sex steroid levels, and high myopia in the Taiwanese population. (21921981)
2011
28
Risk factors for hyperopia and myopia in preschool children the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. (21856013)
2011
29
Drug-induced myopia, hyperopia and accommodation disorders. (20738037)
2010
30
Absence of association between COL1A1 polymorphisms and high myopia in the Japanese population. (18836165)
2009
31
Corneal topography six years after photorefractive keratectomy for myopia and myopic astigmatism. (19507798)
2009
32
Association of PAX6 polymorphisms with high myopia in Han Chinese nuclear families. (19124844)
2009
33
A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1. (19779542)
2009
34
Inherited partial aniridia, microcornea with high myopia and Bergmeister's papilla: a new phenotypic expression. (18292626)
2008
35
Wavefront-guided LASIK for the correction of primary myopia and astigmatism a report by the American Academy of Ophthalmology. (18598819)
2008
36
A genome-wide scan maps a novel high myopia locus to 5p15. (18421076)
2008
37
Application of fluorescence difference gel electrophoresis technology in searching for protein biomarkers in chick myopia. (17924678)
2007
38
Analysis of single nucleotide polymorphisms at 13 loci within the transforming growth factor-induced factor gene shows no association with high myopia in Japanese subjects. (17048038)
2006
39
Fundamentals of modern treatment of myopia]. (16519089)
2005
40
Effect of peripapillary chorioretinal atrophy on GDx parametersin patients with degenerative myopia. (12427231)
2002
41
Excessive myopia and anisometropia associated with familial exudative vitreoretinopathy. (12173668)
2002
42
A study on the prevention and treatment of myopia with nacre on chicks. (11428903)
2001
43
Iatrogenic keratoconus: corneal ectasia following laser in situ keratomileusis for myopia. (10676799)
2000
44
High myopia, hypertelorism, iris coloboma, exomphalos, absent corpus callosum, and sensorineural deafness: report of a case and further evidence for autosomal recessive inheritance. (10794262)
2000
45
Clinical features and surgery for acquired progressive esotropia associated with severe myopia. (10071152)
1999
46
Autosomal dominant typical coloboma associated with unilateral pseudoptosis, myopia and cataract. (7585914)
1995
47
Bullous keratopathy after anterior-posterior radial keratotomy for myopia for myopic astigmatism. (7081358)
1982
48
Stickler syndrome. Presenting as a syndrome of cleft palate, myopia and blindness inherited as a dominant trait. (4218495)
1974
49
Recessive sex-linked inheritance of congenital external ophthalmoplegia and myopia coincident with other dysplasias. A reappraisal after 15 years. (5928925)
1966
50
Retinal changes in degenerative myopia. (13900972)
1962

Genetic Variations for Myopia

Expression for genes affiliated with Myopia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myopia

Search GEO for disease gene expression data for Myopia.

Pathways for genes affiliated with Myopia

Compounds for genes affiliated with Myopia

GO Terms for genes affiliated with Myopia

Sources:
16Gene Ontology
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Biological processes related to Myopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to stimulusGO:05089610.6NYX, CLDN19

Products for genes affiliated with Myopia

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Sources for Myopia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet