MCID: MYP006
MIFTS: 41

Myopia malady

Genetic diseases, Eye diseases, Rare diseases categories
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Summaries for Myopia

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MalaCards based summary: Myopia, also known as near-sightedness, is related to myopia 6 and astigmatism. An important gene associated with Myopia is ZNF644 (zinc finger protein 644). Affiliated tissues include eye, endothelial and retina.

Aliases & Classifications for Myopia

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Myopia, Aliases & Descriptions:

Name: Myopia 8 62
Near-Sightedness 8 62
 
Near Vision 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology8 DOID:11830
ICD9CM27 367.1
SNOMED-CT57 57190000, 155133003
MeSH34 D009216

Related Diseases for Myopia

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Diseases in the Myopia 6 family:

myopia Myopia 14
Myopia 12 Myopia 8
Myopia 9 Myopia 11
Myopia 16 Myopia 19
Myopia 17 Myopia 10
Myopia 15 Myopia 7
Myopia-3 Myopia 18
Myopia 5 Myopia-2
Myopia 13 Myopia-1

Diseases related to Myopia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 306)
idRelated DiseaseScoreTop Affiliating Genes
1myopia 630.7FMOD, ZNF644, NYX
2astigmatism10.7
3hyperopia10.6
4choroiditis10.6
5retinitis10.6
6refractive error10.6
7degenerative myopia10.6
8polydactyly myopia syndrome10.4
9cataract10.4
10macular holes10.4
11open-angle glaucoma10.3
12amblyopia10.3
13esotropia10.3
14retinal detachment10.3
15anisometropia10.3
16blindness10.3
17primary open angle glaucoma10.3
18blepharoptosis myopia ectopia lentis10.3
19congenital stationary night blindness10.3
20night blindness10.3
21strabismus10.3
22presbyopia10.2
23x-linked congenital stationary night blindness10.2
24coloboma10.2
25exotropia10.2
26retinoschisis10.2
27aplasia cutis myopia10.2
28sinus node disease and myopia10.2
29endotheliitis10.2
30aniseikonia10.2
31corneal ectasia10.2
32eye disease10.2
33donnai-barrow syndrome10.2
34dandy-walker malformation with mental retardation, macrocephaly, myopia and brachytelephalangy10.2
35x-linked cone dysfunction syndrome with myopia10.2
36keratoconus10.1
37gyrate atrophy10.1
38achromatopsia 310.1
39noble bass sherman syndrome10.1
40myopia 21, autosomal dominant10.1
41myopia 22, autosomal dominant10.1
42epiphyseal dysplasia, multiple, with myopia and deafness10.1
43myopia 1310.1
44facial dysmorphism - macrocephaly - myopia - dandy-walker malformation10.1
45diabetic retinopathy10.0
46retinopathy of prematurity10.0
47aniridia10.0
48chorioretinitis10.0
49corneal dystrophy10.0
50retinal degeneration10.0

Graphical network of the top 20 diseases related to Myopia:



Diseases related to myopia

Symptoms for Myopia

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Drugs & Therapeutics for Myopia

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Drug clinical trials:

Search ClinicalTrials for Myopia

Search NIH Clinical Center for Myopia

Genetic Tests for Myopia

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Anatomical Context for Myopia

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MalaCards organs/tissues related to Myopia:

32
Eye, Endothelial, Retina, Testes, Heart, Cortex

Animal Models for Myopia or affiliated genes

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Publications for Myopia

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Articles related to Myopia:

(show top 50)    (show all 867)
idTitleAuthorsYear
1
Macular parameters of Stratus optical coherence tomography for assessing glaucoma in high myopia. (25349103)
2014
2
Correlation between central corneal thickness and myopia in Taiwan. (24388054)
2014
3
Comparative Evaluation of Higher-Order Aberrations and Corneal Asphericity Between Wavefront-guided and Aspheric LASIK for Myopia. (25375851)
2014
4
Generational difference of refractive error and risk factors in the Handan Offspring Myopia Study. (25097244)
2014
5
Peripheral optical quality and myopia progression in children. (24253497)
2014
6
Measurement of Scleral Thickness using Swept-Source Optical Coherence Tomography in Open-Angle Glaucoma Patients with Myopia. (24412142)
2014
7
Association of Lumican gene polymorphism with high myopia: a meta-analysis. (24061151)
2013
8
Co-existent choroidal neovascular membrane and macular hole in pathologic myopia: a long follow-up clinical outcome and literature review. (24392342)
2013
9
Retinal nerve fiber layer in primary open-angle glaucoma with high myopia determined by optical coherence tomography and scanning laser polarimetry. (23595371)
2013
10
Peripheral defocus and myopia progression in myopic children randomly assigned to wear single vision and progressive addition lenses. (23838771)
2013
11
Clear lens phacoemulsification combined with vitrectomy to correct high myopia: four years of follow-up. (23257681)
2013
12
Effect of myopia and age on optic disc margin anatomy within the parapapillary atrophy area. (23851575)
2013
13
Heritability of myopia and ocular biometrics in Koreans: the healthy twin study. (23620424)
2013
14
The effect of the Chinese Cultural Revolution and Great Leap Forward on the prevalence of myopia. (24197389)
2013
15
Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. (23933737)
2013
16
Aqueous Concentrations of Vascular Endothelial Growth Factor in Eyes with High Myopia with and without Choroidal Neovascularization. (23533702)
2013
17
Myopia control with orthokeratology contact lenses in Spain: a comparison of vision-related quality-of-life measures between orthokeratology contact lenses and single-vision spectacles. (23392299)
2013
18
Femtosecond (FS) laser vision correction procedure for moderate to high myopia: a prospective study of ReLEx(Ar) flex and comparison with a retrospective study of FS-laser in situ keratomileusis. (22512839)
2013
19
A contralateral, randomized comparison of optimized prolate ablation and conventional LASIK for myopia with the NIDEK excimer laser platform. (22767164)
2012
20
Baseline characteristics of nearwork-induced transient myopia. (23187872)
2012
21
The impact of parental myopia on myopia in Chinese children: population-based evidence. (22922777)
2012
22
Atropine for the treatment of childhood myopia: safety and efficacy of 0.5%, 0.1%, and 0.01% doses (Atropine for the Treatment of Myopia 2). (21963266)
2012
23
Ten SNPs of PAX6, Lumican, and MYOC genes are not associated with high myopia in Han Chinese. (22809227)
2012
24
High myopia as a risk factor in primary open angle glaucoma. (23275912)
2012
25
On the dangers of methodolatry, moral hazard and myopia in research. (22176663)
2012
26
Acquired optic nerve and peripapillary pits in pathologic myopia. (22494632)
2012
27
Prevalence of myopia in a population with malocclusions. (23046255)
2012
28
Prevalence of myopia and its association with diabetic retinopathy in subjects with type II diabetes mellitus: A population-based study. (22993463)
2012
29
Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. (21095009)
2011
30
Nature and nurture: the complex genetics of myopia and refractive error. (21155761)
2011
31
A functional polymorphism at 3'UTR of the PAX6 gene may confer risk for extreme myopia in the Chinese. (21421876)
2011
32
Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population. (21640322)
2011
33
Pigmented free-floating vitreous cyst in a patient with high myopia and uveal coloboma simulating choroidal melanoma. (21485975)
2011
34
Age-related changes of phoria myopia in patients with intermittent exotropia. (19184303)
2009
35
Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. (19836009)
2009
36
Myocilin polymorphisms and high myopia in subjects of European origin. (19180258)
2009
37
Prevalence of myopia and hyperopia among urban and rural schoolchildren in Poland. (19127805)
2008
38
Pupillography of relative afferent pupillary defects in amblyopia associated with peripapillary myelinated nerve fibers and myopia. (18825905)
2008
39
Active cyclotorsion error correction during LASIK for myopia and myopic astigmatism with the NIDEK EC-5000 CX III laser. (18047004)
2007
40
Evidence for delayed presbyopia after photorefractive keratectomy for myopia. (16650666)
2006
41
The role of the retinal pigment epithelium in eye growth regulation and myopia: a review. (16079001)
2005
42
X-linked high myopia associated with cone dysfunction. (15197065)
2004
43
Fixation linked hypotropia in high myopia. A report of two similar cases. (12597767)
2003
44
Myopia and models and mechanisms of refractive error control. (12064076)
2002
45
Volume estimation of excimer laser tissue ablation for correction of spherical myopia and hyperopia. (11980859)
2002
46
Intraocular lens implantation and laser in situ keratomileusis (bioptics) to correct high myopia and hyperopia with astigmatism. (11316030)
2001
47
Clinical features and surgery for acquired progressive esotropia associated with severe myopia. (10071152)
1999
48
A second locus for familial high myopia maps to chromosome 12q. (9792869)
1998
49
Prolidase deficiency associated with pathologic myopia. (9587929)
1998
50
Flicker parameters are different for suppression of myopia and hyperopia. (9373666)
1997

Variations for Myopia

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Expression for genes affiliated with Myopia

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Expression patterns in normal tissues for genes affiliated with Myopia

Search GEO for disease gene expression data for Myopia.

Pathways for genes affiliated with Myopia

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Compounds for genes affiliated with Myopia

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GO Terms for genes affiliated with Myopia

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Biological processes related to Myopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to stimulusGO:0508969.9CLDN19, NYX

Products for genes affiliated with Myopia

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  • Antibodies
  • Proteins
  • Lysates

Sources for Myopia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet