MCID: MYP006
MIFTS: 41

Myopia malady

Eye diseases category

Summaries for Myopia

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32MalaCards
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MalaCards: Myopia, also known as near-sightedness, is related to myopia 6 and astigmatism. An important gene associated with Myopia is NYX (nyctalopin). Affiliated tissues include eye, endothelial and retina.

Aliases & Classifications for Myopia

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

myopia 8 60
near-sightedness 8
near vision 8


External Ids:

Disease Ontology8 DOID:11830
MeSH34 D009216
SNOMED-CT56 155133003, 57190000
ICD9CM27 367.1

Related Diseases for Myopia

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Myopia 6 family:

myopia Myopia 14
Myopia 12 Myopia 8
Myopia 9 Myopia 11
Myopia 16 Myopia 19
Myopia 17 Myopia 10
Myopia 15 Myopia 7
Myopia-3 Myopia 18
Myopia 5 Myopia-2
Myopia 13 Myopia-1

Diseases related to Myopia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 286)
idRelated DiseaseScoreTop Affiliating Genes
1myopia 630.4NYX, ZNF644, FMOD
2astigmatism10.6
3choroiditis10.6
4retinitis10.6
5refractive error10.5
6degenerative myopia10.5
7glaucoma10.5
8cataract10.4
9polydactyly myopia syndrome10.3
10macular holes10.3
11open-angle glaucoma10.3
12esotropia10.3
13retinal detachment10.3
14amblyopia10.3
15primary open angle glaucoma10.2
16blepharoptosis myopia ectopia lentis10.2
17anisometropia10.2
18congenital stationary night blindness10.2
19night blindness10.2
20strabismus10.2
21presbyopia10.2
22coloboma10.1
23retinoschisis10.1
24x-linked congenital stationary night blindness10.1
25aplasia cutis myopia10.1
26sinus node disease and myopia10.1
27aniseikonia10.1
28corneal ectasia10.1
29donnai-barrow syndrome10.1
30dandy-walker malformation with mental retardation, macrocephaly, myopia and brachytelephalangy10.1
31myopia 22, autosomal dominant10.1
32gyrate atrophy10.1
33exotropia10.1
34eye disease10.1
35keratoconus10.1
36optic atrophy10.1
37myopia 21, autosomal dominant10.1
38epiphyseal dysplasia, multiple, with myopia and deafness10.1
39facial dysmorphism - macrocephaly - myopia - dandy-walker malformation10.1
40x-linked cone dysfunction syndrome with myopia10.1
41retinopathy of prematurity10.0
42chorioretinitis10.0
43corneal dystrophy10.0
44retinal degeneration10.0
45scleritis10.0
46cohen syndrome10.0
47anophthalmia or microphthalmia, retinal dystrophy and/or myopia associated with brain anomalies10.0
48stickler syndrome type 110.0
49noble bass sherman syndrome10.0
50optic atrophy opthalmoplegia ptosis deafness myopia10.0

Graphical network of the top 20 diseases related to Myopia:



Diseases related to myopia

Clinical Features for Myopia

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Drugs & Therapeutics for Myopia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Myopia

Drug clinical trials:

Search ClinicalTrials for Myopia

Search NIH Clinical Center for Myopia

Search CenterWatch for Myopia

Genetic Tests for Myopia

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Anatomical Context for Myopia

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32MalaCards
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MalaCards organs/tissues related to Myopia:

32
Eye, Endothelial, Retina, Testes, Heart, Cortex

Animal Models for Myopia or affiliated genes

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Publications for Myopia

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Sources:
50PubMed
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Articles related to Myopia:

(show top 50)    (show all 837)
idTitleAuthorsYear
1
Comparison of spectral domain and swept-source optical coherence tomography in pathological myopia. (24434661)
2014
2
Atropine for the treatment of childhood myopia: changes after stopping atropine 0.01%, 0.1% and 0.5%. (24315293)
2014
3
Laser in situ keratomileusis for astigmatisma88a8oa880.75 Diopter combined with low myopia: a retrospective data analysis. (24393469)
2014
4
Form deprivation and lens-induced myopia: are they different? (23662966)
2013
5
Evaluating the Association between Pathological Myopia and SNPs in RASGRF1. ACTC1 and GJD2 Genes at Chromosome 15q14 and 15q25 in a Chinese Population. (23834555)
2013
6
Late Acute Myopia Syndrome Induced by Combination of Sulfonamide Drugs. (23661047)
2013
7
Full-field electroretinogram findings in children in the atropine treatment for myopia (ATOM2) study. (23292524)
2013
8
Birth order and myopia: what are the messages to readers? (24229068)
2013
9
The economic cost of myopia in adults aged over 40 years in Singapore. (24159089)
2013
10
Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort. (23734076)
2013
11
Protective effects of high ambient lighting on the development of form-deprivation myopia in rhesus monkeys. (22169102)
2012
12
Outcome of photodynamic therapy in choroidal neovascularization due to pathologic myopia and related factors. (22350116)
2012
13
Posterior corneal curvature assessment after Epi-LASIK for myopia: comparison of Orbscan II and Pentacam imaging. (22323878)
2012
14
The novel human p.I587V variant in the ZNF644 gene is unlikely to be the pathogenic cause of dominantly inherited high myopia in a Chinese patient. (23024268)
2012
15
Vision Related Quality of Life in Myopia; Photorefractive Keratectomy versus Nonsurgical Optical Correction. (23264864)
2012
16
Peripheral refraction in myopia corrected with spectacles versus contact lenses. (22577970)
2012
17
Myopia. (22559900)
2012
18
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. (22665138)
2012
19
Alterations in protein expression in tree shrew sclera during development of lens-induced myopia and recovery. (22039233)
2012
20
Investigating the relationship between UMODL1 gene polymorphisms and high myopia: a case-control study in Chinese. (22857148)
2012
21
Genetic variants on chromosome 1q41 influence ocular axial length and high myopia. (22685421)
2012
22
High prevalence of myopia and high myopia in 5060 Chinese university students in Shanghai. (23060137)
2012
23
Myopia progression in children is linked with reduced foveal mfERG response. (22761262)
2012
24
Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population. (21640322)
2011
25
Systematic investigation of the relationship between high myopia and polymorphisms of the MMP2, TIMP2, and TIMP3 genes by a DNA pooling approach. (21421877)
2011
26
Dopamine antagonists and brief vision distinguish lens-induced- and form-deprivation-induced myopia. (21872586)
2011
27
PAX6 haplotypes are associated with high myopia in Han chinese. (21589860)
2011
28
Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort. (20435602)
2010
29
The development of myopia among children with intermittent exotropia. (20172074)
2010
30
High myopia is not associated with the SNPs in the TGIF, lumican, TGFB1, and HGF genes. (19060265)
2009
31
The association of haplotype at the lumican gene with high myopia susceptibility in Taiwanese patients. (19616852)
2009
32
Pupillography of relative afferent pupillary defects in amblyopia associated with peripapillary myelinated nerve fibers and myopia. (18825905)
2008
33
Visual disability, visual function, and myopia among rural chinese secondary school children: the Xichang Pediatric Refractive Error Study (X-PRES)--report 1. (18378579)
2008
34
Visual outcomes of wavefront-guided laser in situ keratomileusis in eyes with moderate or high myopia and compound myopic astigmatism. (18165076)
2008
35
Changes in aqueous vascular endothelial growth factor and pigment epithelial-derived factor levels following intravitreal bevacizumab injections for choroidal neovascularization secondary to age-related macular degeneration or pathologic myopia. (18728623)
2008
36
Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia. (18334955)
2008
37
Evidence for delayed presbyopia after photorefractive keratectomy for myopia. (16650666)
2006
38
Heritability of refractive error and ocular biometrics: the Genes in Myopia (GEM) twin study. (17065484)
2006
39
Family-based association analysis of hepatocyte growth factor (HGF) gene polymorphisms in high myopia. (16723436)
2006
40
Defining myopia using refractive error and uncorrected logMAR visual acuity >0.3 from 1334 Singapore school children ages 7-9 years. (16488963)
2006
41
Evaluation of MMP3 and TIMP1 as candidate genes for high myopia in young Taiwanese men. (16935611)
2006
42
Heritability of refractive error and familial aggregation of myopia in an elderly American population. (15851555)
2005
43
Pax-6 expression in posthatch chick retina during and recovery from form-deprivation myopia. (15855761)
2004
44
Unilateral macular retinoschisis with stellate foveal appearance in two females with myopia. (10847501)
2000
45
Familial exudative vitreoretinopathy associated with monocular axial myopia. (10380037)
1999
46
Retinal detachment with high myopia in the Rubinstein-Taybi syndrome. (1818231)
1991
47
Photocoagulation scar expansion after laser therapy for choroidal neovascularization in degenerative myopia. (1708513)
1990
48
Anisometropia and changes in anisometropia in school myopia. (2188189)
1990
49
Dominant inheritance of multiple epiphyseal dysplasia, myopia and deafness. (699354)
1978
50
A simplified technique for surgical treatment of degenerative myopia. (5054236)
1972

Genetic Variations for Myopia

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Expression for genes affiliated with Myopia

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myopia

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Pathways for genes affiliated with Myopia

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Compounds for genes affiliated with Myopia

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GO Terms for genes affiliated with Myopia

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16Gene Ontology
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Biological processes related to Myopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to stimulusGO:05089610.6NYX, CLDN19

Products for genes affiliated with Myopia

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  • Antibodies
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Sources for Myopia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet