MCID: MYS001
MIFTS: 33

Myositis Ossificans

Categories: Muscle diseases

Aliases & Classifications for Myositis Ossificans

MalaCards integrated aliases for Myositis Ossificans:

Name: Myositis Ossificans 12 72 14 69
Ossification - Muscle 12
Myisitis Ossificans 12

Classifications:



External Ids:

Disease Ontology 12 DOID:668
MeSH 41 D009221
NCIt 46 C3253
UMLS 69 C0027122

Summaries for Myositis Ossificans

Disease Ontology : 12 A myositis that is accompanied by ossification of muscle tissue or bony deposits in the muscles.

MalaCards based summary : Myositis Ossificans, also known as ossification - muscle, is related to fibrodysplasia ossificans progressiva and osteogenic sarcoma. An important gene associated with Myositis Ossificans is USP6 (Ubiquitin Specific Peptidase 6). The drugs Tretinoin and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include bone, lymph node and bone marrow.

Wikipedia : 72 Myositis ossificans comprises two syndromes characterized by heterotopic ossification (calcification) of... more...

Related Diseases for Myositis Ossificans

Diseases related to Myositis Ossificans via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 fibrodysplasia ossificans progressiva 33.2 BMP1 FOS
2 osteogenic sarcoma 29.5 BMP1 FOS
3 osseous heteroplasia, progressive 11.2
4 myositis 11.2
5 tetanus 10.3
6 sarcoma 10.2
7 cervicitis 10.2
8 inflammatory spondylopathy 10.1
9 poliomyelitis 10.1
10 spondylitis 10.1
11 aneurysmal bone cysts 10.0
12 ankylosis 10.0
13 aneurysm 10.0
14 spondyloarthropathy 1 9.9
15 cherubism 9.9
16 chondrosarcoma 9.9
17 osteoid osteoma 9.9
18 episodic pain syndrome, familial, 1 9.9
19 arthritis 9.9
20 dermatomyositis 9.9
21 ischemia 9.9
22 compartment syndrome 9.9
23 periostitis 9.9
24 hemophilia 9.9
25 soft tissue sarcoma 9.9
26 amyotrophic lateral sclerosis 7 9.9 FOS MRPS22
27 lipomatosis, multiple 9.8
28 radioulnar synostosis 9.8
29 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 9.8
30 sarcoma, synovial 9.8
31 branchiootic syndrome 1 9.8
32 alveolar soft part sarcoma 9.8
33 niemann-pick disease, type b 9.8
34 aplastic anemia 9.8
35 chromosome 16p13.3 deletion syndrome, proximal 9.8
36 factor xi deficiency 9.8
37 gastric cancer 9.8
38 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.8
39 takenouchi-kosaki syndrome 9.8
40 cerebral palsy 9.8
41 childhood type dermatomyositis 9.8
42 leukemia 9.8
43 niemann-pick disease 9.8
44 spinal cord injury 9.8
45 lymphoma 9.8
46 connective tissue benign neoplasm 9.8
47 thrombosis 9.8
48 fibrous dysplasia 9.8
49 spindle cell lipoma 9.8
50 osteomalacia 9.8

Graphical network of the top 20 diseases related to Myositis Ossificans:



Diseases related to Myositis Ossificans

Symptoms & Phenotypes for Myositis Ossificans

Drugs & Therapeutics for Myositis Ossificans

Drugs for Myositis Ossificans (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tretinoin Approved, Investigational, Nutraceutical Phase 3,Phase 2 302-79-4 5538
2 Pharmaceutical Solutions Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Efficacy and Safety Study of Palovarotene for the Treatment of FOP Recruiting NCT03312634 Phase 3 Palovarotene
2 An Efficacy and Safety Study of Palovarotene to Treat Preosseous Flare-ups in FOP Subjects Completed NCT02190747 Phase 2 Palovarotene;Placebo
3 A Study to Examine the Safety, Tolerability and Effects on Abnormal Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans Progressiva Recruiting NCT03188666 Phase 2 REGN2477;Matching placebo
4 An Open-Label Extension Study of Palovarotene Treatment in FOP Active, not recruiting NCT02279095 Phase 2 Palovarotene dose level 1;Palovarotene dose level 2;Palovarotene dose level 3;Palovarotene dose level 4
5 An Open-Label Extension Study of Palovarotene to Prevent Heterotopic Ossification in FOP Subjects in France Active, not recruiting NCT02979769 Phase 2 Palovarotene dose level 1;Palovarotene dose level 2
6 In-Home Evaluation of Episodic Administration of Palovarotene in Fibrodysplasia Ossificans Progressiva (FOP) Subjects Suspended NCT02521792 Phase 2 Palovarotene
7 Urine Sample Collection From FOP Patients Completed NCT02066324
8 The Fibrodysplasia Ossificans Progressiva (FOP) Connection Registry Recruiting NCT02745158
9 A Natural History Study of Fibrodysplasia Ossificans Progressiva (FOP) Active, not recruiting NCT02322255
10 Discovering the Gene(s) Causing Developmental Dysplasia of the Hip (DDH) Active, not recruiting NCT01193673

Search NIH Clinical Center for Myositis Ossificans

Genetic Tests for Myositis Ossificans

Anatomical Context for Myositis Ossificans

MalaCards organs/tissues related to Myositis Ossificans:

38
Bone, Lymph Node, Bone Marrow, Ovary, Breast, Brain, Spinal Cord

Publications for Myositis Ossificans

Articles related to Myositis Ossificans:

(show top 50) (show all 559)
# Title Authors Year
1
Paratesticular myositis ossificans of the spermatic cord. ( 29301813 )
2018
2
Extraskeletal osteosarcoma arising in myositis ossificans: a case report and review of the literature. ( 28536749 )
2017
3
Myositis ossificans in elbow mimicking soft tissue sarcoma: Similar clinical and radiological findings. ( 28641932 )
2017
4
Unsupervised Exercise-Induced Myositis Ossificans in the Brachialis Muscle of a Young Healthy Male: A Case Report. ( 28795074 )
2017
5
Imaging in myositis ossificans: Bone scintigraphy and 18F-fluorodeoxyglucose positron emission tomography/computed tomography. ( 28325501 )
2017
6
Myositis Ossificans of the Hip Due to Pyogenic Arthritis Caused by Campylobacter fetus Subspecies fetus. ( 28420848 )
2017
7
A fatal case of metastatic squamous cell carcinoma in a patient with myositis ossificans traumatica. ( 28741585 )
2017
8
Heterotopic ossification (myositis ossificans progressiva): A condition interfering with rheumatic disease. ( 28293462 )
2017
9
Surgical excision of symptomatic mature posttraumatic myositis ossificans: characteristics and outcomes in 32 athletes. ( 28780628 )
2017
10
Traumatic myositis ossificans circumscripta (MOC). ( 28679511 )
2017
11
Management of Myositis Ossificans of the Hand: A Case Report and a Review of the Literature. ( 28385291 )
2017
12
Myositis ossificans in children: a review. ( 28275867 )
2017
13
Myositis ossificans of the longus coli muscle following cervical spine fracture-dislocation. ( 27077572 )
2016
14
Intra-abdominal myositis ossificans in an asymptomatic patient during closure of a Hartmann's colostomy. ( 27887014 )
2016
15
A rare case of pediatric Nontraumatic Myositis Ossificans in the posterior triangle. ( 27063765 )
2016
16
Myositis ossificans after navigated knee surgery: A report of two cases and literature review. ( 26993571 )
2016
17
MYOSITIS OSSIFICANS TRAUMATICA IN A VAMPIRE BAT (DESMODUS ROTUNDUS). ( 27691970 )
2016
18
Myositis Ossificans Associated with Prayer Mark. ( 27107753 )
2016
19
Posttraumatic myositis ossificans of the hand : A locally aggressive malignancy-mimicking tumor. ( 27048331 )
2016
20
MR imaging and ultrasonography findings of early myositis ossificans: a case report. ( 27511030 )
2016
21
Myositis ossificans progressive: case report. ( 27800117 )
2016
22
Non-traumatic myositis ossificans circumscripta at elbow joint in a 9-year old child. ( 27140223 )
2016
23
Myositis ossificans: A rare location in the foot. Report of a case and review of literature. ( 27474831 )
2016
24
Nontraumatic Myositis Ossificans of Hip: A Case Presentation. ( 27437157 )
2016
25
Pre-surgical CT-assessment of neurogenic myositis ossificans of the hip and risk factors of recurrence: a series of 101 consecutive patients. ( 27756329 )
2016
26
Synovial Sarcoma Mimicking Myositis Ossificans. ( 27595081 )
2016
27
Myositis ossificans of the platysma mimicking a malignancy: a case report with review of the literature. ( 26904497 )
2016
28
Poster 92 Identifying Nonhereditary Myositis Ossificans Traumaticus in a Community Hospital. ( 27672859 )
2016
29
Myositis ossificans of the masseter muscle: A rare location. Report of a case and review of literature. ( 27034763 )
2016
30
(18)F-fluorodeoxyglucose-positron emission tomography avid paraspinal soft-tissue mass mimicking a malign neoplasm: non-traumatic myositis ossificans. ( 27001110 )
2016
31
Myositis ossificans traumatica (circumscripta) and return to sport: A retrospective series of 19 cases. ( 26934992 )
2016
32
Myositis ossificans of the quadriceps femoris in a soccer player. ( 26264943 )
2015
33
The stone women-Myositis ossificans Progressiva. ( 27299087 )
2015
34
A Rare Metastatic Myositis Ossificans of Obturator Muscle Secondary to Urothelial Carcinoma. ( 26500729 )
2015
35
Myositis Ossificans. ( 26320160 )
2015
36
Myositis Ossificans of Rectus Femoris: A Rare Case Report. ( 27299083 )
2015
37
Adult Niemann-Pick disease type B with myositis ossificans: a case report. ( 26338042 )
2015
38
A Rare Case Of Non Traumatic Myositis Ossificans Circumscripta. ( 27299058 )
2015
39
Avulsion Fracture and Myositis Ossificans in a Professional Teenage Dancer: A Case Report. ( 26046617 )
2015
40
Myositis ossificans circumscripta. ( 26215631 )
2015
41
Post-infectious myositis ossificans in medial, lateral pterygoid muscles: A case report and review of the literature. ( 25621069 )
2015
42
Atraumatic Myositis Ossificans of Iliopsoas Excised through an ASIS Osteotomy Case Report and Description of a Novel Technique. ( 26517003 )
2015
43
Pediatric myositis ossificans mimicking osteosarcoma. ( 26508182 )
2015
44
Delayed Sciatic Nerve Injury Resulting from Myositis Ossificans Traumatica. ( 26548968 )
2015
45
Myositis Ossificans in the Thigh of a Lacrosse Player. ( 26313164 )
2015
46
Myositis ossificans traumatica of the medial pterygoid muscle following a third molar extraction. ( 25487562 )
2015
47
Myositis Ossificans Circumscripta in the Masseter Muscle Mimicking Phleboliths. ( 26147036 )
2015
48
An Unusual Presentation of Myositis Ossificans in a Pediatric Patient. ( 26491916 )
2015
49
Myositis ossificans occupying the thenar region: a case report. ( 25943356 )
2015
50
Myositis ossificans on the forearm in a 10-year-old girl. ( 25647566 )
2015

Variations for Myositis Ossificans

Expression for Myositis Ossificans

Search GEO for disease gene expression data for Myositis Ossificans.

Pathways for Myositis Ossificans

GO Terms for Myositis Ossificans

Sources for Myositis Ossificans

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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