MCID: MYX008
MIFTS: 42

Myxoid Chondrosarcoma malady

Summaries for Myxoid Chondrosarcoma

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Myxoid chondrosarcoma is a type of sarcoma. more...

MalaCards: Myxoid Chondrosarcoma is related to chondrosarcoma and extraskeletal myxoid chondrosarcoma. An important gene associated with Myxoid Chondrosarcoma is TAF15 (TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa), and among its related pathways is Transcriptional misregulation in cancer. The compounds askin and nor 1 have been mentioned in the context of this disorder. Affiliated tissues include bone, breast and lung, and related mouse phenotypes are hematopoietic system and cellular.

Aliases & Classifications for Myxoid Chondrosarcoma

About this section
Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 39NCIt
See all sources

Aliases & Descriptions:

myxoid chondrosarcoma 8 60


External Ids:

Disease Ontology8 DOID:5861
SNOMED-CT56 189881008, 75622000
NCIt39 C4303

Related Diseases for Myxoid Chondrosarcoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Myxoid Chondrosarcoma family:

Adult Myxoid Chondrosarcoma

Diseases related to Myxoid Chondrosarcoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 86)
idRelated DiseaseScoreTop Affiliating Genes
1chondrosarcoma31.9FUS, S100B, S100A1, EWSR1, NR4A3, MUC1
2extraskeletal myxoid chondrosarcoma31.8TAF15, NR4A3, TFG
3sarcoma30.9S100B, S100A1, EWSR1, CREB3L2, NR4A3, MUC1
4chordoma30.5S100B, S100A1, MUC1
5synovial sarcoma30.2EWSR1
6myxoid liposarcoma30.1FUS, EWSR1
7lipoma30.1FUS, S100A1, C11orf95
8liposarcoma30.1C11orf95, EWSR1, TSN, FUS
9intracranial chondrosarcoma10.5
10pediatric myxoid chondrosarcoma10.4
11adult myxoid chondrosarcoma10.4
12extraosseous chondrosarcoma10.4
13mesenchymal chondrosarcoma10.3
14thyroiditis10.3
15adult extraosseous chondrosarcoma10.1
16epithelial-myoepithelial carcinoma10.1
17localized chondrosarcoma10.1
18extraskeletal mesenchymal chondrosarcoma10.1
19chondroid lipoma10.1
20chondroid chordoma10.1
21encephalomyelitis10.1
22parachordoma10.1
23polyneuropathy10.1
24glomus tumor10.0S100A1
25papilloma10.0NR1H2
26angiomyolipoma10.0S100A1
27thymus cancer10.0MUC1
28fibrosarcoma10.0CREB3L2
29retroperitoneal leiomyosarcoma10.0SMARCB1
30central nervous system cancer10.0ENO2
31amyotrophic lateral sclerosis10.0FUS, TAF15
32epulis10.0ENO2
33cerebral primitive neuroectodermal tumor10.0ENO2, EWSR1
34nephrogenic adenoma10.0S100A1
35langerhans-cell histiocytosis10.0S100B, S100A1
36desmoplastic small round cell tumor10.0EWSR1, MUC1
37rhabdoid tumor10.0SMARCB1, MUC1
38rosai-dorfman disease10.0S100B
39prostate cancer10.0NR1H2, ENO2
40ganglioglioma10.0ENO2, S100B
41fibrous meningioma10.0S100B, MUC1
42myoepithelioma10.0EWSR1, S100A1, S100B
43olfactory neuroblastoma10.0ENO2, S100B
44cutaneous fibrous histiocytoma10.0S100A1, S100B
45choroid plexus papilloma10.0S100B, MUC1
46anaplastic ependymoma10.0S100B, MUC1
47clear cell sarcoma10.0FUS, EWSR1, S100B
48spindle cell sarcoma10.0MUC1, S100B
49pleomorphic adenoma10.0PLAGL1
50dermatofibrosarcoma protuberans10.0MUC1, S100A1, S100B

Graphical network of the top 20 diseases related to Myxoid Chondrosarcoma:



Diseases related to myxoid chondrosarcoma

Clinical Features for Myxoid Chondrosarcoma

About this section

Drugs & Therapeutics for Myxoid Chondrosarcoma

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Myxoid Chondrosarcoma

Drug clinical trials:

Search ClinicalTrials for Myxoid Chondrosarcoma

Search NIH Clinical Center for Myxoid Chondrosarcoma

Search CenterWatch for Myxoid Chondrosarcoma

Genetic Tests for Myxoid Chondrosarcoma

About this section

Anatomical Context for Myxoid Chondrosarcoma

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Myxoid Chondrosarcoma:

32
Bone, Breast, Lung, Thyroid, Heart, Bone marrow, Uterus, Liver, Pancreas, Pineal

Animal Models for Myxoid Chondrosarcoma or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Myxoid Chondrosarcoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053979.1NR4A3, NR1H2, CHI3L1, TEC, TSN, FUS
2MP:00053848.4SMARCB1, EWSR1, NR4A3, NR1H2, CHI3L1, PLAGL1

Publications for Myxoid Chondrosarcoma

About this section
Sources:
50PubMed
See all sources

Articles related to Myxoid Chondrosarcoma:

(show top 50)    (show all 204)
idTitleAuthorsYear
1
Myxoid chondrosarcoma of sphenoid bone. (23189013)
2012
2
Extraskeletal myxoid chondrosarcoma: a review of 23 patients treated at a single referral center with long-term follow-up. (22678528)
2012
3
Intracranial extraskeletal myxoid chondrosarcoma : case report and literature review. (23115670)
2012
4
Intra-articular extraskeletal myxoid chondrosarcoma of the ankle. (22438126)
2012
5
A case of highly aggressive extraskeletal myxoid chondrosarcoma. (21941486)
2011
6
Cellular variant of extraskeletal myxoid chondrosarcoma with Ewing's sarcoma-like areas: a diagnostic pitfall in core needle biopsy. (20496272)
2010
7
Extraskeletal myxoid chondrosarcoma of the perineum. (19309044)
2009
8
Extraskeletal myxoid chondrosarcoma: Diagnosis of a rare soft tissue tumor based on fine needle aspiration cytology. (21938148)
2009
9
Extraskeletal myxoid chondrosarcoma: rare presentation in the knee joint space. (19968226)
2009
10
Extraskeletal myxoid chondrosarcoma: a study using a quick-freezing and deep-etching method. (19784746)
2009
11
Spectrum of cytomorphological features, including literature review, of an extraskeletal myxoid chondrosarcoma with t(9;22)(q22;q12) (TEC/EWS) results in one case. (18925568)
2008
12
SMARCB1/INI1 protein expression in round cell soft tissue sarcomas associated with chromosomal translocations involving EWS: a special reference to SMARCB1/INI1 negative variant extraskeletal myxoid chondrosarcoma. (18580682)
2008
13
Myxoid chondrosarcoma in the calcaneus: a case report with MR imaging findings. (17219232)
2007
14
Myxoid chondrosarcoma of the sinonasal cavity in a child: a case report. (17923790)
2007
15
Extraskeletal myxoid chondrosarcoma: a report of a gynecologic case. (15992919)
2005
16
The gene expression profile of extraskeletal myxoid chondrosarcoma. (15920699)
2005
17
Extraskeletal myxoid chondrosarcoma in a cow. (15980139)
2005
18
TFG is a novel fusion partner of NOR1 in extraskeletal myxoid chondrosarcoma. (15188455)
2004
19
Bulbous urethra involved in perineal extraskeletal myxoid chondrosarcoma in a child. (15157219)
2004
20
Microtubule-associated protein-2 and class III beta-tubulin are expressed in extraskeletal myxoid chondrosarcoma. (12748252)
2003
21
Primary intracranial myxoid chondrosarcoma: report of a case and review of the literature. (12692436)
2003
22
Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcoma-cytogenetic, molecular genetic, and cDNA microarray analyses. (12598313)
2003
23
Extraskeletal myxoid chondrosarcoma of the infratemporal fossa: a case report. (12767886)
2003
24
Extraskeletal myxoid chondrosarcoma: a light microscopic, immunohistochemical, ultrastructural and immuno-ultrastructural study indicating neuroendocrine differentiation. (11737310)
2001
25
Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 18 cases. (11679947)
2001
26
Expression of the intermediate filament peripherin in extraskeletal myxoid chondrosarcoma. (10728817)
2000
27
Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma. (10478665)
1999
28
Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11). (10602519)
1999
29
High-grade extraskeletal myxoid chondrosarcoma: a high-grade epithelioid malignancy. (10469211)
1999
30
Extraskeletal and Skeletal Myxoid Chondrosarcoma: A Multiparameter Analysis of Three Cases Including Cytogenetic Analysis and Fluorescence In Situ Hybridization. (10330205)
1996
31
Fusion of the EWS gene to a DNA segment from 9q22-31 in a human myxoid chondrosarcoma. (7539287)
1995
32
Translocation t(9;22)(q22;q12) is a primary cytogenetic abnormality in extraskeletal myxoid chondrosarcoma. (7635565)
1995
33
Extraskeletal myxoid chondrosarcoma with intracisternal microtubules. (8191636)
1994
34
Case report 829: Intramuscular myxoid chondrosarcoma. (8191303)
1994
35
Extraskeletal myxoid chondrosarcoma: fine-needle aspiration biopsy findings. (7534681)
1994
36
Extraskeletal myxoid chondrosarcoma. A clinicopathologic study of ten patients with long-term follow-up. (1451062)
1992
37
Embryonal form of extraskeletal myxoid chondrosarcoma with intermediate filament positive hyaline-like globules. (1384692)
1992
38
Extraskeletal myxoid chondrosarcoma of the pleura. Report of a case clinically simulating mesothelioma. (1553915)
1992
39
Cellular variant of extraskeletal myxoid chondrosarcoma of abdominal wall--a case report with comparative immunohistochemical study on cartilaginous collagenous proteins in various myxoid mesenchymal tumors. (1531226)
1992
40
Chromosomal abnormality t(9;22)(q22;q12) in an extraskeletal myxoid chondrosarcoma characterized by fine needle aspiration cytology, electron microscopy, immunohistochemistry and DNA flow cytometry. (1782363)
1991
41
Extraskeletal myxoid chondrosarcoma--a review of three cases. (2090579)
1990
42
Myxoid chondrosarcoma of the mediastinum. (2561417)
1989
43
Recurrent breakpoints at 9q31 and 22q12.2 in extraskeletal myxoid chondrosarcoma. (3422040)
1988
44
Primary myxoid chondrosarcoma of the thyroid gland. (3337623)
1988
45
Extraskeletal myxoid chondrosarcoma in young children. (2835146)
1988
46
Aspiration biopsy cytology of metastatic extraskeletal myxoid chondrosarcoma and its cytologic differential diagnosis. (3861047)
1985
47
Immunohistochemistry and histogenesis of extraskeletal myxoid chondrosarcoma. (4045599)
1985
48
Extraskeletal myxoid chondrosarcoma. A case report with histochemical and ultrastructural features. (6678591)
1983
49
Mandibular metastasis of an extraskeletal myxoid chondrosarcoma arising on the plantar surface of the foot: report of case. (273676)
1978
50
A comparative ultrastructural study of mesenchymal chondrosarcoma and myxoid chondrosarcoma. (4834151)
1974

Genetic Variations for Myxoid Chondrosarcoma

About this section

Expression for genes affiliated with Myxoid Chondrosarcoma

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Myxoid Chondrosarcoma

Search GEO for disease gene expression data for Myxoid Chondrosarcoma.

Pathways for genes affiliated with Myxoid Chondrosarcoma

About this section
Sources:
29KEGG
See all sources

Pathways related to Myxoid Chondrosarcoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9FUS, TAF15, NR4A3, EWSR1

Compounds for genes affiliated with Myxoid Chondrosarcoma

About this section
Sources:
44Novoseek, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR
See all sources

Compounds related to Myxoid Chondrosarcoma according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1askin4410.4ENO2, EWSR1
2nor 14410.4EWSR1, NR4A3
3edss4410.3S100B, ENO2
4eosin4410.3MUC1, S100B
5smcc4410.3NR1H2, ENO2
6mucicarmine4410.3S100B, S100A1, MUC1
7b 7234410.3MUC1, S100A1, S100B
8s 1004410.3ENO2, MUC1, S100B
9reticulin4410.2MUC1, S100B
10olopatadine44 1111.1S100B, S100A1
11hematoxylin4410.1ENO2, MUC1, S100A1, S100B
12formaldehyde44 2411.1S100B, NR1H2, MUC1, ENO2
13paraffin449.9S100B, S100A1, EWSR1, MUC1, ENO2
14zinc44 2410.8S100B, S100A1, EWSR1, NR1H2, PLAGL1, FUS
15toluidine449.8ENO2, S100A1
16progesterone44 59 28 11 2413.7ENO2, MUC1, NR1H2, S100A1, S100B
17retinoic acid44 2410.6S100B, S100A1, EWSR1, NR1H2, MUC1, ENO2
18testosterone44 59 11 2412.5S100B, NR1H2, MUC1, PLAGL1, ENO2
19tyrosine449.3S100B, S100A1, EWSR1, TFG, NR4A3, MUC1

GO Terms for genes affiliated with Myxoid Chondrosarcoma

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Myxoid Chondrosarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:0056348.5SMARCB1, S100A1, EWSR1, CREB3L2, NR4A3, NR1H2

Molecular functions related to Myxoid Chondrosarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:0445489.8S100B, S100A1
2identical protein bindingGO:0428029.6FUS, TFG, EWSR1, S100A1, S100B
3sequence-specific DNA bindingGO:0435659.6TSN, SIX3, NR1H2, NR4A3, CREB3L2

Products for genes affiliated with Myxoid Chondrosarcoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Myxoid Chondrosarcoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet