MCID: MYX008
MIFTS: 42

Myxoid Chondrosarcoma malady

Summaries for Myxoid Chondrosarcoma

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63Wikipedia, 32MalaCards
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Wikipedia:63 Myxoid chondrosarcoma is a type of sarcoma. more...

MalaCards: Myxoid Chondrosarcoma is related to chondrosarcoma and extraskeletal myxoid chondrosarcoma. An important gene associated with Myxoid Chondrosarcoma is TAF15 (TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa), and among its related pathways is Transcriptional misregulation in cancer. The compounds askin and nor 1 have been mentioned in the context of this disorder. Affiliated tissues include bone, breast and lung, and related mouse phenotypes are hematopoietic system and cellular.

Aliases & Classifications for Myxoid Chondrosarcoma

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8Disease Ontology, 60UMLS, 56SNOMED-CT, 39NCIt
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Aliases & Descriptions:

myxoid chondrosarcoma 8 60


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Disease Ontology8 DOID:5861
SNOMED-CT56 189881008, 75622000
NCIt39 C4303

Related Diseases for Myxoid Chondrosarcoma

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17GeneCards, 18GeneDecks
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Diseases in the Myxoid Chondrosarcoma family:

Adult Myxoid Chondrosarcoma

Diseases related to Myxoid Chondrosarcoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 86)
idRelated DiseaseScoreTop Affiliating Genes
1chondrosarcoma31.9FUS, S100B, S100A1, EWSR1, NR4A3, MUC1
2extraskeletal myxoid chondrosarcoma31.8TAF15, NR4A3, TFG
3sarcoma30.9S100B, S100A1, EWSR1, CREB3L2, NR4A3, MUC1
4chordoma30.5S100B, S100A1, MUC1
5synovial sarcoma30.2EWSR1
6myxoid liposarcoma30.1FUS, EWSR1
7lipoma30.1FUS, S100A1, C11orf95
8liposarcoma30.1C11orf95, EWSR1, TSN, FUS
9intracranial chondrosarcoma10.5
10pediatric myxoid chondrosarcoma10.4
11adult myxoid chondrosarcoma10.4
12extraosseous chondrosarcoma10.4
13mesenchymal chondrosarcoma10.3
14thyroiditis10.3
15adult extraosseous chondrosarcoma10.1
16epithelial-myoepithelial carcinoma10.1
17localized chondrosarcoma10.1
18extraskeletal mesenchymal chondrosarcoma10.1
19chondroid lipoma10.1
20chondroid chordoma10.1
21encephalomyelitis10.1
22parachordoma10.1
23polyneuropathy10.1
24glomus tumor10.0S100A1
25papilloma10.0NR1H2
26angiomyolipoma10.0S100A1
27thymus cancer10.0MUC1
28fibrosarcoma10.0CREB3L2
29retroperitoneal leiomyosarcoma10.0SMARCB1
30central nervous system cancer10.0ENO2
31amyotrophic lateral sclerosis10.0FUS, TAF15
32epulis10.0ENO2
33cerebral primitive neuroectodermal tumor10.0ENO2, EWSR1
34nephrogenic adenoma10.0S100A1
35langerhans-cell histiocytosis10.0S100B, S100A1
36desmoplastic small round cell tumor10.0EWSR1, MUC1
37rhabdoid tumor10.0SMARCB1, MUC1
38rosai-dorfman disease10.0S100B
39prostate cancer10.0NR1H2, ENO2
40ganglioglioma10.0ENO2, S100B
41fibrous meningioma10.0S100B, MUC1
42myoepithelioma10.0EWSR1, S100A1, S100B
43olfactory neuroblastoma10.0ENO2, S100B
44cutaneous fibrous histiocytoma10.0S100A1, S100B
45choroid plexus papilloma10.0S100B, MUC1
46anaplastic ependymoma10.0S100B, MUC1
47clear cell sarcoma10.0FUS, EWSR1, S100B
48spindle cell sarcoma10.0MUC1, S100B
49pleomorphic adenoma10.0PLAGL1
50dermatofibrosarcoma protuberans10.0MUC1, S100A1, S100B

Graphical network of the top 20 diseases related to Myxoid Chondrosarcoma:



Diseases related to myxoid chondrosarcoma

Clinical Features for Myxoid Chondrosarcoma

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Drugs & Therapeutics for Myxoid Chondrosarcoma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Myxoid Chondrosarcoma

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Anatomical Context for Myxoid Chondrosarcoma

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32MalaCards
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MalaCards organs/tissues related to Myxoid Chondrosarcoma:

32
Bone, Breast, Lung, Thyroid, Heart, Bone marrow, Uterus, Liver, Pancreas, Pineal

Animal Models for Myxoid Chondrosarcoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Myxoid Chondrosarcoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053979.1NR4A3, NR1H2, CHI3L1, TEC, TSN, FUS
2MP:00053848.4SMARCB1, EWSR1, NR4A3, NR1H2, CHI3L1, PLAGL1

Publications for Myxoid Chondrosarcoma

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50PubMed
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Articles related to Myxoid Chondrosarcoma:

(show top 50)    (show all 204)
idTitleAuthorsYear
1
Primary myxoid chondrosarcoma of the breast. (24417859)
2014
2
Anthracycline-based chemotherapy in extraskeletal myxoid chondrosarcoma: a retrospective study. (24345066)
2013
3
Calcaneal myxoid chondrosarcoma: a rare case. (23591173)
2012
4
Extraskeletal myxoid chondrosarcoma of the thigh with a t(9;17) translocation. (22740963)
2012
5
NR4A3 rearrangement reliably distinguishes between the clinicopathologically overlapping entities myoepithelial carcinoma of soft tissue and cellular extraskeletal myxoid chondrosarcoma. (22569967)
2012
6
Primary intracranial extraskeletal myxoid chondrosarcoma. (22426765)
2012
7
Extraskeletal myxoid chondrosarcoma of the left buccal mucosa. (22843913)
2012
8
A myxoid chondrosarcoma associated with an anti-Hu-positive paraneoplastic encephalomyelitis. (20443130)
2011
9
Parasellar myxoid chondrosarcoma: a rare variant of cranial chondrosarcoma. (22198591)
2011
10
Extraskeletal myxoid chondrosarcoma: a case report of complete remission by chemotherapy and review of the literature. (22315646)
2010
11
Fine-needle aspiration cytology of extraskeletal myxoid chondrosarcoma: a case report. (19894252)
2010
12
Supraclavicular extraskeletal myxoid chondrosarcoma presenting with a sensorimotor polyneuropathy associated with anti-Hu antibodies. (19711588)
2009
13
Metastases of a myxoid chondrosarcoma to the breast. (18850510)
2009
14
Testicular metastasis of extraskeletal myxoid chondrosarcoma: report of first case. (18308379)
2008
15
Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma. (18587326)
2008
16
An undifferentiated sarcoma in a rat resembling extraskeletal myxoid chondrosarcoma in man. (17676526)
2007
17
A case of petrous bone myxoid chondrosarcoma associated with cerebellar hemorrhage. (18095103)
2005
18
Prognosis of extraskeletal myxoid chondrosarcoma. (12820050)
2003
19
Effusion cytology of metastatic extraskeletal myxoid chondrosarcoma. (12672100)
2003
20
Extraskeletal myxoid chondrosarcoma: a Multi-Institutional Study of 42 Cases in Japan. (12599237)
2003
21
Pathologic quiz case: chest wall mass in a 74-year-old man. Extraskeletal myxoid chondrosarcoma. (14521439)
2003
22
Extraskeletal myxoid chondrosarcoma arising in the finger. (11981607)
2002
23
Extraskeletal myxoid chondrosarcoma of the knee. (10883455)
2000
24
Metastases to the liver from extraskeletal myxoid chondrosarcoma and successful treatment with percutaneous ethanol injection. (10767194)
2000
25
Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and ploidy analysis of 23 cases. (10955458)
2000
26
Extraskeletal Myxoid Chondrosarcoma with Rhabdoid Features, with Special Reference to Its Aggressive Behavior. (11493979)
2000
27
Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation]. (11038663)
1999
28
Identification of a novel fusion gene involving hTAFII68 and CHN from a t(9;17)(q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma. (10602520)
1999
29
Extraskeletal myxoid chondrosarcoma: multimodal diagnosis and identification of a new cytogenetic subgroup characterized by t(9;17)(q22;q11). (10592057)
1999
30
Skeletal and extraskeletal myxoid chondrosarcoma: related or distinct tumors? (10410173)
1999
31
Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma. (8570200)
1996
32
Partial deletions of the CDKN2 and MTS2 putative tumor suppressor genes in a myxoid chondrosarcoma. (8689636)
1996
33
Translocation (9;22)(q22;q12). A recurrent chromosome abnormality in extraskeletal myxoid chondrosarcoma. (7773957)
1995
34
Myxoid chondrosarcoma of soft tissue and bone: a retrospective study of 11 cases. (7590695)
1995
35
The diagnosis of extraskeletal myxoid chondrosarcoma by fine needle aspiration. (8520007)
1995
36
Extraskeletal myxoid chondrosarcoma. Long-term experience with chemotherapy. (7900708)
1995
37
Metastatic extraskeletal myxoid chondrosarcoma. Successful therapy with interferon alfa-2b. (7606973)
1995
38
General case of the day. Myxoid chondrosarcoma of the cavernous sinus. (7501862)
1995
39
Myxoid chondrosarcoma-induced pathologic fracture. (7932117)
1994
40
FNA of extraskeletal myxoid chondrosarcoma: cytomorphologic, EM, and X-ray microanalysis features. (7924809)
1994
41
Myxoid chondrosarcoma of the abdominal aorta. (8473087)
1993
42
Extraskeletal myxoid chondrosarcoma. A clinicopathologic and immunohistochemical study of two cases. (8249186)
1993
43
Unusual extraskeletal myxoid chondrosarcoma. (1373011)
1992
44
Molecular analysis of a myxoid chondrosarcoma with rearrangements of chromosomes 10 and 22. (1969328)
1990
45
Extraskeletal myxoid chondrosarcoma of the head and neck: a case report. (2508028)
1989
46
Skeletal myxoid chondrosarcoma with microtubular aggregates within rough endoplasmic reticulum. (3337620)
1988
47
Metastatic extraosseous myxoid chondrosarcoma of spermatic cord. (4035849)
1985
48
Myxoid chondrosarcoma of the os calcis: a case report. (6500415)
1984
49
Myxoid chondrosarcoma of the synovial tissue. A clinicopathologic, histochemical, and ultrastructural analysis. (6414683)
1983
50
Extraskeletal myxoid chondrosarcoma--a clinicopathologic and electron microscopic study. (7270148)
1981

Genetic Variations for Myxoid Chondrosarcoma

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Expression for genes affiliated with Myxoid Chondrosarcoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Myxoid Chondrosarcoma

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Pathways for genes affiliated with Myxoid Chondrosarcoma

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29KEGG
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Pathways related to Myxoid Chondrosarcoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9FUS, TAF15, NR4A3, EWSR1

Compounds for genes affiliated with Myxoid Chondrosarcoma

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44Novoseek, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR
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Compounds related to Myxoid Chondrosarcoma according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1askin4410.4ENO2, EWSR1
2nor 14410.4EWSR1, NR4A3
3edss4410.3S100B, ENO2
4eosin4410.3MUC1, S100B
5smcc4410.3NR1H2, ENO2
6mucicarmine4410.3S100B, S100A1, MUC1
7b 7234410.3MUC1, S100A1, S100B
8s 1004410.3ENO2, MUC1, S100B
9reticulin4410.2MUC1, S100B
10olopatadine44 1111.1S100B, S100A1
11hematoxylin4410.1ENO2, MUC1, S100A1, S100B
12formaldehyde44 2411.1S100B, NR1H2, MUC1, ENO2
13paraffin449.9S100B, S100A1, EWSR1, MUC1, ENO2
14zinc44 2410.8S100B, S100A1, EWSR1, NR1H2, PLAGL1, FUS
15toluidine449.8ENO2, S100A1
16progesterone44 59 28 11 2413.7ENO2, MUC1, NR1H2, S100A1, S100B
17retinoic acid44 2410.6S100B, S100A1, EWSR1, NR1H2, MUC1, ENO2
18testosterone44 59 11 2412.5S100B, NR1H2, MUC1, PLAGL1, ENO2
19tyrosine449.3S100B, S100A1, EWSR1, TFG, NR4A3, MUC1

GO Terms for genes affiliated with Myxoid Chondrosarcoma

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16Gene Ontology
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Cellular components related to Myxoid Chondrosarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:0056348.5SMARCB1, S100A1, EWSR1, CREB3L2, NR4A3, NR1H2

Molecular functions related to Myxoid Chondrosarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:0445489.8S100B, S100A1
2identical protein bindingGO:0428029.6FUS, TFG, EWSR1, S100A1, S100B
3sequence-specific DNA bindingGO:0435659.6TSN, SIX3, NR1H2, NR4A3, CREB3L2

Products for genes affiliated with Myxoid Chondrosarcoma

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Sources for Myxoid Chondrosarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet