MCID: NRC003
MIFTS: 29

Narcissistic Personality Disorder

Categories: Mental diseases

Aliases & Classifications for Narcissistic Personality Disorder

MalaCards integrated aliases for Narcissistic Personality Disorder:

Name: Narcissistic Personality Disorder 12 72 51 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2745
ICD10 32 F60.81
ICD9CM 34 301.81
MeSH 41 D010554
NCIt 46 C92635
SNOMED-CT 64 192493008 80711002
UMLS 69 C0027402

Summaries for Narcissistic Personality Disorder

Disease Ontology : 12 A personality disorder that involves an excessive preoccupation with issues of personal adequacy, power, prestige and vanity.

MalaCards based summary : Narcissistic Personality Disorder is related to disease of mental health and personality disorder. An important gene associated with Narcissistic Personality Disorder is SMPD1 (Sphingomyelin Phosphodiesterase 1), and among its related pathways/superpathways are Prolactin Signaling Pathway and Salmonella infection (KEGG). Affiliated tissues include brain, and related phenotype is growth/size/body region.

Wikipedia : 72 Narcissistic personality disorder (NPD) is a personality disorder in which there is a long-term pattern... more...

Related Diseases for Narcissistic Personality Disorder

Diseases related to Narcissistic Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 15)
# Related Disease Score Top Affiliating Genes
1 disease of mental health 29.6 ADAMTS2 OPRM1 WASF2
2 personality disorder 11.0
3 borderline personality disorder 10.2
4 histrionic personality disorder 10.1 OPRM1 PIR
5 attention deficit-hyperactivity disorder 9.9
6 aging 9.9
7 frontotemporal dementia 9.9
8 bipolar disorder 9.9
9 dementia 9.9
10 mood disorder 9.9
11 ring chromosome y syndrome 9.9
12 chronic pain 9.8 JUN OPRM1
13 dependent personality disorder 9.8 SMPD1 WASF2
14 constipation 9.6 FLNA OPRM1
15 avoidant personality disorder 9.5 FLNA WASF2

Comorbidity relations with Narcissistic Personality Disorder via Phenotypic Disease Network (PDN):


Anxiety Dependent Personality Disorder
Dysthymic Disorder Histrionic Personality Disorder
Hypertension, Essential Major Depressive Disorder

Graphical network of the top 20 diseases related to Narcissistic Personality Disorder:



Diseases related to Narcissistic Personality Disorder

Symptoms & Phenotypes for Narcissistic Personality Disorder

MGI Mouse Phenotypes related to Narcissistic Personality Disorder:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.23 ADAMTS2 CGA FLNA JUN OPRM1 PIR

Drugs & Therapeutics for Narcissistic Personality Disorder

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Plasticity of the Compassionate Brain Completed NCT01833104

Search NIH Clinical Center for Narcissistic Personality Disorder

Genetic Tests for Narcissistic Personality Disorder

Anatomical Context for Narcissistic Personality Disorder

MalaCards organs/tissues related to Narcissistic Personality Disorder:

38
Brain

Publications for Narcissistic Personality Disorder

Articles related to Narcissistic Personality Disorder:

(show top 50) (show all 125)
# Title Authors Year
1
Quasi-psychosis in covert Narcissistic Personality Disorder-A case report. ( 29272784 )
2018
2
Clinician Ratings of Vulnerable and Grandiose Narcissistic Features: Implications for an Expanded Narcissistic Personality Disorder Diagnosis. ( 29215903 )
2017
3
Narcissistic Personality Disorder and suicidal behavior in mood disorders. ( 27816770 )
2017
4
Intersect between self-esteem and emotion regulation in narcissistic personality disorder - implications for alliance building and treatment. ( 28191317 )
2017
5
Narcissistic Personality Disorder in Clinical Health Psychology Practice: Case Studies of Comorbid Psychological Distress and Life-Limiting Illness. ( 28767013 )
2017
6
The role of shame and self-compassion in psychotherapy for narcissistic personality disorder: An exploratory study. ( 29265698 )
2017
7
Examining sex differences in DSM-IV-TR narcissistic personality disorder symptom expression using Item Response Theory (IRT). ( 29291575 )
2017
8
Clinical Characteristics of Comorbid Narcissistic Personality Disorder in Patients With Borderline Personality Disorder. ( 28758884 )
2017
9
Countertransference when working with narcissistic personality disorder: An empirical investigation. ( 28581327 )
2017
10
Narcissistic personality disorder and suicide. ( 27658843 )
2016
11
Narcissistic Personality Disorder and the Structure of Common Mental Disorders. ( 27617650 )
2016
12
Demystifying Complexes, Transference, and Narcissistic Personality Disorder with Jung and Lacan. ( 27335529 )
2016
13
Borderline Personality Disorder and Narcissistic Personality Disorder Diagnoses From the Perspective of the DSM-5 Personality Traits: A Study on Italian Clinical Participants. ( 27660996 )
2016
14
A masked negative self-esteem? Implicit and explicit self-esteem in patients with Narcissistic Personality Disorder. ( 27254651 )
2016
15
A systematic review on the relationship between antisocial, borderline and narcissistic personality disorder diagnostic traits and risk of violence to others in a clinical and forensic sample. ( 27777779 )
2016
16
Sex Bias in Classifying Borderline and Narcissistic Personality Disorder. ( 26421970 )
2015
17
Narcissistic personality disorder: diagnostic and clinical challenges. ( 25930131 )
2015
18
Beauvoir and demystifying paradoxical characteristics of narcissistic personality disorder. ( 25969623 )
2015
19
Brain structure in narcissistic personality disorder: a VBM and DTI pilot study. ( 25492857 )
2015
20
Inpatient Therapeutic Assessment With Narcissistic Personality Disorder. ( 26408333 )
2015
21
Beyond the diagnostic traits: A collaborative exploratory diagnostic process for dimensions and underpinnings of narcissistic personality disorder. ( 25314232 )
2014
22
The maturation of narcissism: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314235 )
2014
23
A Fairbairnian structural analysis of the narcissistic personality disorder. ( 24866161 )
2014
24
Introduction to the special series on "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314230 )
2014
25
Moving the field forward: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314233 )
2014
26
The narcissism epidemic: commentary on modernity and narcissistic personality disorder. ( 24796568 )
2014
27
Narcissistic personality disorder: an integrative review of recent empirical data and current definitions. ( 24633939 )
2014
28
How to spot a narcissist: Mental health literacy with respect to Narcissistic Personality Disorder. ( 25279811 )
2014
29
Narcissistic personality disorder and becoming old. ( 24399659 )
2014
30
A comparison of the criterion validity of popular measures of narcissism and narcissistic personality disorder via the use of expert ratings. ( 24773036 )
2014
31
Stability of narcissistic personality disorder: tracking categorical and dimensional rating systems over a two-year period. ( 24512458 )
2014
32
Vulnerable narcissism: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314236 )
2014
33
Ruminations on narcissistic personality disorder. ( 24796569 )
2014
34
Empathy in narcissistic personality disorder: from clinical and empirical perspectives. ( 24512457 )
2014
35
Phenomenology in need of treatment: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314234 )
2014
36
Response to commentaries: modernity and narcissistic personality disorder. ( 24796571 )
2014
37
The Narcissistic Personality Inventory: a useful tool for assessing pathological narcissism? Evidence from patients with Narcissistic Personality Disorder. ( 23101721 )
2013
38
An update on narcissistic personality disorder. ( 23187086 )
2013
39
Fear and decision-making in narcissistic personality disorder-a link between psychoanalysis and neuroscience. ( 24174893 )
2013
40
Gray matter abnormalities in patients with narcissistic personality disorder. ( 23777939 )
2013
41
The validity of the Personality Diagnostic Questionnaire-4 Narcissistic Personality Disorder scale for assessing pathological grandiosity. ( 23101760 )
2013
42
Shame in patients with narcissistic personality disorder. ( 24321228 )
2013
43
When grandiosity and vulnerability collide: Implicit and explicit self-esteem in patients with narcissistic personality disorder. ( 22902785 )
2013
44
Borderline personality disorder, bipolar disorder, depression, attention deficit/hyperactivity disorder, and narcissistic personality disorder: Practical differential diagnosis. ( 23428169 )
2013
45
Narcissistic Personality Disorder in DSM-5. ( 23834518 )
2013
46
Attachment and object relations in patients with narcissistic personality disorder: implications for therapeutic process and outcome. ( 23996275 )
2013
47
Subtypes, dimensions, levels, and mental states in narcissism and narcissistic personality disorder. ( 22740389 )
2012
48
Metacognitive interpersonal therapy for narcissistic personality disorder and associated perfectionism. ( 22729358 )
2012
49
Modernity and Narcissistic Personality Disorder. ( 22800179 )
2012
50
Alliance building and narcissistic personality disorder. ( 22729478 )
2012

Variations for Narcissistic Personality Disorder

Expression for Narcissistic Personality Disorder

Search GEO for disease gene expression data for Narcissistic Personality Disorder.

Pathways for Narcissistic Personality Disorder

Pathways related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.88 CGA FLNA JUN
2 11.07 FLNA JUN WASF2
3 10.81 CGA JUN
4 10.63 CGA JUN TTF2

GO Terms for Narcissistic Personality Disorder

Biological processes related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to hormone stimulus GO:0032870 9.26 CGA JUN
2 response to radiation GO:0009314 9.16 JUN OPRM1
3 response to cocaine GO:0042220 8.96 OPRM1 SMPD1
4 monocyte differentiation GO:0030224 8.62 JUN PIR

Sources for Narcissistic Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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