MCID: NRC003
MIFTS: 28

Narcissistic Personality Disorder malady

Categories: Mental diseases

Aliases & Classifications for Narcissistic Personality Disorder

Aliases & Descriptions for Narcissistic Personality Disorder:

Name: Narcissistic Personality Disorder 12 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2745
ICD10 33 F60.81
ICD9CM 35 301.81
MeSH 42 D010554
NCIt 47 C92635
SNOMED-CT 64 192493008 80711002
UMLS 69 C0027402

Summaries for Narcissistic Personality Disorder

Disease Ontology : 12 A personality disorder that involves an excessive preoccupation with issues of personal adequacy, power, prestige and vanity.

MalaCards based summary : Narcissistic Personality Disorder is related to personality disorder and xanthomatosis. An important gene associated with Narcissistic Personality Disorder is SMPD1 (Sphingomyelin Phosphodiesterase 1), and among its related pathways/superpathways are Prolactin Signaling Pathway and Salmonella infection (KEGG). The drug Silicon has been mentioned in the context of this disorder. Affiliated tissues include brain, and related phenotype is growth/size/body region.

Wikipedia : 71 Narcissistic personality disorder (NPD) is a personality disorder in which there is a long-term pattern... more...

Related Diseases for Narcissistic Personality Disorder

Diseases related to Narcissistic Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
id Related Disease Score Top Affiliating Genes
1 personality disorder 30.9 ADAMTS2 OPRM1 WASF2
2 xanthomatosis 10.1 OPRM1 PIR
3 borderline personality disorder 10.1
4 ck syndrome 10.0 FLNA OPRM1
5 encephalopathy 9.9 JUN OPRM1
6 dissociative disorder 9.9 SMPD1 WASF2
7 attention deficit-hyperactivity disorder 9.8
8 bipolar disorder 9.8
9 dementia 9.8
10 mood disorder 9.8
11 chronic cervicitis 9.7 FLNA WASF2
12 mycobacterium avium complex disease 8.6 ADAMTS2 CGA FLNA JUN LINC01191 OPRM1

Comorbidity relations with Narcissistic Personality Disorder via Phenotypic Disease Network (PDN):


Anxiety Disorder Dependent Personality Disorder
Dysthymic Disorder Histrionic Personality Disorder
Hypertension, Essential

Graphical network of the top 20 diseases related to Narcissistic Personality Disorder:



Diseases related to Narcissistic Personality Disorder

Symptoms & Phenotypes for Narcissistic Personality Disorder

MGI Mouse Phenotypes related to Narcissistic Personality Disorder:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.23 ADAMTS2 CGA FLNA JUN OPRM1 PIR

Drugs & Therapeutics for Narcissistic Personality Disorder

Drugs for Narcissistic Personality Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Silicon 7440-21-3 4082203

Interventional clinical trials:


id Name Status NCT ID Phase
1 Plasticity of the Compassionate Brain Completed NCT01833104
2 Personality Pathology and Cerebral Processing in Eating Disorders Recruiting NCT02980120

Search NIH Clinical Center for Narcissistic Personality Disorder

Genetic Tests for Narcissistic Personality Disorder

Anatomical Context for Narcissistic Personality Disorder

MalaCards organs/tissues related to Narcissistic Personality Disorder:

39
Brain

Publications for Narcissistic Personality Disorder

Articles related to Narcissistic Personality Disorder:

(show top 50) (show all 117)
id Title Authors Year
1
Narcissistic Personality Disorder and suicidal behavior in mood disorders. ( 27816770 )
2017
2
Demystifying Complexes, Transference, and Narcissistic Personality Disorder with Jung and Lacan. ( 27335529 )
2016
3
A systematic review on the relationship between antisocial, borderline and narcissistic personality disorder diagnostic traits and risk of violence to others in a clinical and forensic sample. ( 27777779 )
2016
4
A masked negative self-esteem? Implicit and explicit self-esteem in patients with Narcissistic Personality Disorder. ( 27254651 )
2016
5
Narcissistic Personality Disorder and the Structure of Common Mental Disorders. ( 27617650 )
2016
6
Narcissistic personality disorder and suicide. ( 27658843 )
2016
7
Borderline Personality Disorder and Narcissistic Personality Disorder Diagnoses From the Perspective of the DSM-5 Personality Traits: A Study on Italian Clinical Participants. ( 27660996 )
2016
8
Sex Bias in Classifying Borderline and Narcissistic Personality Disorder. ( 26421970 )
2015
9
Inpatient Therapeutic Assessment With Narcissistic Personality Disorder. ( 26408333 )
2015
10
Brain structure in narcissistic personality disorder: a VBM and DTI pilot study. ( 25492857 )
2015
11
Narcissistic personality disorder: diagnostic and clinical challenges. ( 25930131 )
2015
12
Beauvoir and demystifying paradoxical characteristics of narcissistic personality disorder. ( 25969623 )
2015
13
Ruminations on narcissistic personality disorder. ( 24796569 )
2014
14
Response to commentaries: modernity and narcissistic personality disorder. ( 24796571 )
2014
15
The narcissism epidemic: commentary on modernity and narcissistic personality disorder. ( 24796568 )
2014
16
Narcissistic personality disorder and becoming old. ( 24399659 )
2014
17
Phenomenology in need of treatment: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314234 )
2014
18
How to spot a narcissist: Mental health literacy with respect to Narcissistic Personality Disorder. ( 25279811 )
2014
19
Introduction to the special series on "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314230 )
2014
20
Stability of narcissistic personality disorder: tracking categorical and dimensional rating systems over a two-year period. ( 24512458 )
2014
21
Moving the field forward: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314233 )
2014
22
The maturation of narcissism: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314235 )
2014
23
A Fairbairnian structural analysis of the narcissistic personality disorder. ( 24866161 )
2014
24
Vulnerable narcissism: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314236 )
2014
25
Empathy in narcissistic personality disorder: from clinical and empirical perspectives. ( 24512457 )
2014
26
Beyond the diagnostic traits: A collaborative exploratory diagnostic process for dimensions and underpinnings of narcissistic personality disorder. ( 25314232 )
2014
27
Narcissistic personality disorder: an integrative review of recent empirical data and current definitions. ( 24633939 )
2014
28
A comparison of the criterion validity of popular measures of narcissism and narcissistic personality disorder via the use of expert ratings. ( 24773036 )
2014
29
Narcissistic Personality Disorder in DSM-5. ( 23834518 )
2013
30
An update on narcissistic personality disorder. ( 23187086 )
2013
31
Attachment and object relations in patients with narcissistic personality disorder: implications for therapeutic process and outcome. ( 23996275 )
2013
32
Fear and decision-making in narcissistic personality disorder-a link between psychoanalysis and neuroscience. ( 24174893 )
2013
33
When grandiosity and vulnerability collide: Implicit and explicit self-esteem in patients with narcissistic personality disorder. ( 22902785 )
2013
34
Gray matter abnormalities in patients with narcissistic personality disorder. ( 23777939 )
2013
35
The Narcissistic Personality Inventory: a useful tool for assessing pathological narcissism? Evidence from patients with Narcissistic Personality Disorder. ( 23101721 )
2013
36
Borderline personality disorder, bipolar disorder, depression, attention deficit/hyperactivity disorder, and narcissistic personality disorder: Practical differential diagnosis. ( 23428169 )
2013
37
Shame in patients with narcissistic personality disorder. ( 24321228 )
2013
38
The validity of the Personality Diagnostic Questionnaire-4 Narcissistic Personality Disorder scale for assessing pathological grandiosity. ( 23101760 )
2013
39
Demystifying paradoxical characteristics of narcissistic personality disorder. ( 23723557 )
2012
40
Narcissistic personality disorder: effect on relationships. ( 23472440 )
2012
41
Self- and informant-reported perspectives on symptoms of narcissistic personality disorder. ( 22452774 )
2012
42
Modernity and Narcissistic Personality Disorder. ( 22800179 )
2012
43
Narcissistic pathology as core personality dysfunction: comparing the DSM-IV and the DSM-5 proposal for narcissistic personality disorder. ( 22730037 )
2012
44
Metacognitive interpersonal therapy for narcissistic personality disorder and associated perfectionism. ( 22729358 )
2012
45
Alliance building and narcissistic personality disorder. ( 22729478 )
2012
46
Disturbed emotion recognition in patients with narcissistic personality disorder. ( 22406389 )
2012
47
Subtypes, dimensions, levels, and mental states in narcissism and narcissistic personality disorder. ( 22740389 )
2012
48
Some comments on nomology, diagnostic process, and narcissistic personality disorder in the DSM-5 proposal for personality and personality disorders. ( 22448689 )
2011
49
Validity aspects of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, narcissistic personality disorder construct. ( 21193181 )
2011
50
Narcissistic personality disorder: a clinical perspective. ( 21430487 )
2011

Variations for Narcissistic Personality Disorder

Expression for Narcissistic Personality Disorder

Search GEO for disease gene expression data for Narcissistic Personality Disorder.

Pathways for Narcissistic Personality Disorder

Pathways related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.88 CGA FLNA JUN
2 11.07 FLNA JUN WASF2
3 10.81 CGA JUN
4 10.63 CGA JUN TTF2

GO Terms for Narcissistic Personality Disorder

Biological processes related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular response to hormone stimulus GO:0032870 9.26 CGA JUN
2 response to cocaine GO:0042220 9.16 OPRM1 SMPD1
3 response to radiation GO:0009314 8.96 JUN OPRM1
4 monocyte differentiation GO:0030224 8.62 JUN PIR

Sources for Narcissistic Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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