MCID: NRC003
MIFTS: 28

Narcissistic Personality Disorder malady

Category: Mental diseases

Aliases & Classifications for Narcissistic Personality Disorder

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Aliases & Descriptions for Narcissistic Personality Disorder:

Name: Narcissistic Personality Disorder 11 50 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:2745
ICD1030 F60.81
ICD9CM32 301.81
SNOMED-CT62 192493008, 80711002
MeSH39 D010554
NCIt45 C92635

Summaries for Narcissistic Personality Disorder

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Disease Ontology:11 A personality disorder that involves an excessive preoccupation with issues of personal adequacy, power, prestige and vanity.

MalaCards based summary: Narcissistic Personality Disorder is related to personality disorder and borderline personality disorder. An important gene associated with Narcissistic Personality Disorder is SMPD1 (Sphingomyelin Phosphodiesterase 1), and among its related pathways are Transcription_Role of VDR in regulation of genes involved in osteoporosis and TSH signaling pathway. Affiliated tissues include brain, and related mouse phenotype growth/size/body region.

Wikipedia:71 Narcissistic personality disorder (NPD) is a long-term pattern of abnormal behavior characterized by... more...

Related Diseases for Narcissistic Personality Disorder

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Graphical network of diseases related to Narcissistic Personality Disorder:



Diseases related to narcissistic personality disorder

Symptoms & Phenotypes for Narcissistic Personality Disorder

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MGI Mouse Phenotypes related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053786.7ADAMTS2, CGA, FLNA, JUN, OPRM1, PIR

Drugs & Therapeutics for Narcissistic Personality Disorder

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Drugs for Narcissistic Personality Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Silicon947440-21-34082203
Synonyms:
Si
 
Silica
Silicate
Silicic acid

Interventional clinical trials:

idNameStatusNCT IDPhase
1Plasticity of the Compassionate BrainCompletedNCT01833104
2Personality Pathology and Cerebral Processing in Eating DisordersRecruitingNCT02980120

Search NIH Clinical Center for Narcissistic Personality Disorder

Genetic Tests for Narcissistic Personality Disorder

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Anatomical Context for Narcissistic Personality Disorder

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MalaCards organs/tissues related to Narcissistic Personality Disorder:

36
Brain

Publications for Narcissistic Personality Disorder

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Articles related to Narcissistic Personality Disorder:

(show top 50)    (show all 117)
idTitleAuthorsYear
1
Narcissistic Personality Disorder and suicidal behavior in mood disorders. (27816770)
2017
2
Demystifying Complexes, Transference, and Narcissistic Personality Disorder with Jung and Lacan. (27335529)
2016
3
Narcissistic Personality Disorder and the Structure of Common Mental Disorders. (27617650)
2016
4
Borderline Personality Disorder and Narcissistic Personality Disorder Diagnoses From the Perspective of the DSM-5 Personality Traits: A Study on Italian Clinical Participants. (27660996)
2016
5
A masked negative self-esteem? Implicit and explicit self-esteem in patients with Narcissistic Personality Disorder. (27254651)
2016
6
Narcissistic personality disorder and suicide. (27658843)
2016
7
A systematic review on the relationship between antisocial, borderline and narcissistic personality disorder diagnostic traits and risk of violence to others in a clinical and forensic sample. (27777779)
2016
8
Beauvoir and demystifying paradoxical characteristics of narcissistic personality disorder. (25969623)
2015
9
Brain structure in narcissistic personality disorder: a VBM and DTI pilot study. (25492857)
2015
10
Sex Bias in Classifying Borderline and Narcissistic Personality Disorder. (26421970)
2015
11
Narcissistic personality disorder: diagnostic and clinical challenges. (25930131)
2015
12
Inpatient Therapeutic Assessment With Narcissistic Personality Disorder. (26408333)
2015
13
Beyond the diagnostic traits: A collaborative exploratory diagnostic process for dimensions and underpinnings of narcissistic personality disorder. (25314232)
2014
14
Stability of narcissistic personality disorder: tracking categorical and dimensional rating systems over a two-year period. (24512458)
2014
15
Response to commentaries: modernity and narcissistic personality disorder. (24796571)
2014
16
Empathy in narcissistic personality disorder: from clinical and empirical perspectives. (24512457)
2014
17
Narcissistic personality disorder: an integrative review of recent empirical data and current definitions. (24633939)
2014
18
A comparison of the criterion validity of popular measures of narcissism and narcissistic personality disorder via the use of expert ratings. (24773036)
2014
19
Introduction to the special series on "Narcissistic personality disorder-New perspectives on diagnosis and treatment". (25314230)
2014
20
The narcissism epidemic: commentary on modernity and narcissistic personality disorder. (24796568)
2014
21
A Fairbairnian structural analysis of the narcissistic personality disorder. (24866161)
2014
22
Vulnerable narcissism: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". (25314236)
2014
23
The maturation of narcissism: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". (25314235)
2014
24
How to spot a narcissist: Mental health literacy with respect to Narcissistic Personality Disorder. (25279811)
2014
25
Moving the field forward: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". (25314233)
2014
26
Narcissistic personality disorder and becoming old. (24399659)
2014
27
Ruminations on narcissistic personality disorder. (24796569)
2014
28
Phenomenology in need of treatment: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". (25314234)
2014
29
When grandiosity and vulnerability collide: Implicit and explicit self-esteem in patients with narcissistic personality disorder. (22902785)
2013
30
The validity of the Personality Diagnostic Questionnaire-4 Narcissistic Personality Disorder scale for assessing pathological grandiosity. (23101760)
2013
31
The Narcissistic Personality Inventory: a useful tool for assessing pathological narcissism? Evidence from patients with Narcissistic Personality Disorder. (23101721)
2013
32
Attachment and object relations in patients with narcissistic personality disorder: implications for therapeutic process and outcome. (23996275)
2013
33
Shame in patients with narcissistic personality disorder. (24321228)
2013
34
Narcissistic Personality Disorder in DSM-5. (23834518)
2013
35
Fear and decision-making in narcissistic personality disorder-a link between psychoanalysis and neuroscience. (24174893)
2013
36
An update on narcissistic personality disorder. (23187086)
2013
37
Gray matter abnormalities in patients with narcissistic personality disorder. (23777939)
2013
38
Borderline personality disorder, bipolar disorder, depression, attention deficit/hyperactivity disorder, and narcissistic personality disorder: Practical differential diagnosis. (23428169)
2013
39
Subtypes, dimensions, levels, and mental states in narcissism and narcissistic personality disorder. (22740389)
2012
40
Disturbed emotion recognition in patients with narcissistic personality disorder. (22406389)
2012
41
Narcissistic pathology as core personality dysfunction: comparing the DSM-IV and the DSM-5 proposal for narcissistic personality disorder. (22730037)
2012
42
Demystifying paradoxical characteristics of narcissistic personality disorder. (23723557)
2012
43
Metacognitive interpersonal therapy for narcissistic personality disorder and associated perfectionism. (22729358)
2012
44
Modernity and Narcissistic Personality Disorder. (22800179)
2012
45
Narcissistic personality disorder: effect on relationships. (23472440)
2012
46
Alliance building and narcissistic personality disorder. (22729478)
2012
47
Self- and informant-reported perspectives on symptoms of narcissistic personality disorder. (22452774)
2012
48
Validity aspects of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, narcissistic personality disorder construct. (21193181)
2011
49
Narcissistic personality disorder in DSM-V--in support of retaining a significant diagnosis. (21466253)
2011
50
Lack of empathy in patients with narcissistic personality disorder. (21055831)
2011

Variations for Narcissistic Personality Disorder

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Expression for genes affiliated with Narcissistic Personality Disorder

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Search GEO for disease gene expression data for Narcissistic Personality Disorder.

Pathways for genes affiliated with Narcissistic Personality Disorder

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Pathways related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5CGA, JUN
29.1CGA, JUN, TTF2
3
Show member pathways
9.0CGA, FLNA, JUN
4
Show member pathways
8.5FLNA, JUN, WASF2

GO Terms for genes affiliated with Narcissistic Personality Disorder

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Biological processes related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to cocaineGO:004222010.1OPRM1, SMPD1
2monocyte differentiationGO:003022410.0JUN, PIR
3cellular response to hormone stimulusGO:003287010.0CGA, JUN
4response to radiationGO:00093149.4JUN, OPRM1

Sources for Narcissistic Personality Disorder

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet