MCID: NSP002
MIFTS: 46

Nasopharyngitis

Categories: Respiratory diseases

Aliases & Classifications for Nasopharyngitis

MalaCards integrated aliases for Nasopharyngitis:

Name: Nasopharyngitis 12 72 51 41 14 69
Chronic Nasopharyngitis 12 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10460
ICD10 32 J00 J31.1
ICD9CM 34 472.2
MeSH 41 D009304
NCIt 46 C34837

Summaries for Nasopharyngitis

Disease Ontology : 12 A nasopharyngeal disease which involves inflammation of the nasal passages and upper part of the pharynx.

MalaCards based summary : Nasopharyngitis, also known as chronic nasopharyngitis, is related to nasopharyngeal disease and nasopharyngeal carcinoma. An important gene associated with Nasopharyngitis is DPP4 (Dipeptidyl Peptidase 4), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Interleukin-4 and 13 signaling. The drugs Metformin and Pioglitazone have been mentioned in the context of this disorder. Affiliated tissues include endothelial, lymph node and thyroid.

Wikipedia : 72 The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory... more...

Related Diseases for Nasopharyngitis

Diseases related to Nasopharyngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 279)
# Related Disease Score Top Affiliating Genes
1 nasopharyngeal disease 29.0 ARL2BP DPP4 IL17A IL17F IL17RA LRRC4
2 nasopharyngeal carcinoma 12.5
3 juvenile nasopharyngeal angiofibroma 12.3
4 nasopharyngeal carcinoma 3 12.3
5 nasopharyngeal carcinoma 2 12.2
6 nasopharyngeal teratoma 12.0
7 dandy-walker malformation with nasopharyngeal teratoma and diaphragmatic hernia 11.9
8 nasopharyngeal cancer, childhood 11.8
9 lymphoepithelioma-like carcinoma 11.7
10 common cold 11.7
11 pharyngitis 11.5
12 otosalpingitis 10.9
13 teratoma 10.4
14 chronic rhinitis 10.4
15 stromal keratitis 10.3 IL17A IL17RA
16 endotheliitis 10.2
17 opportunistic mycosis 10.2 IL17A IL17RA
18 otitis media 10.1
19 adenocarcinoma 10.1
20 papillary adenocarcinoma 10.1
21 lymphoma 10.1
22 mastitis 10.0 IL17A LTF
23 acute generalized exanthematous pustulosis 10.0 IL17A IL17F
24 adenoma 10.0
25 pneumonia 10.0
26 hypoxia 10.0
27 esophagitis 10.0
28 thyroiditis 10.0
29 influenza 10.0
30 cervicitis 10.0
31 bronchiolitis 10.0
32 adenoiditis 10.0
33 diphtheria 9.9
34 cleft palate, isolated 9.9
35 pierre robin syndrome 9.9
36 tonsillitis 9.9
37 haemophilus influenzae 9.9
38 aging 9.9
39 sinusitis 9.9
40 dermatomyositis 9.9
41 squamous cell carcinoma 9.9
42 papilloma 9.9
43 cranial nerve palsy 9.9
44 rhinitis 9.9
45 pleomorphic adenoma 9.9
46 rheumatoid lung disease 9.9 IL17A TNFRSF1B
47 chronic mucocutaneous candidiasis 9.9 IL17A IL17F IL17RA
48 blood group, i system 9.9
49 mucositis 9.9
50 pertussis 9.9

Graphical network of the top 20 diseases related to Nasopharyngitis:



Diseases related to Nasopharyngitis

Symptoms & Phenotypes for Nasopharyngitis

Drugs & Therapeutics for Nasopharyngitis

Drugs for Nasopharyngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 4091 14219
2
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
3 Dipeptidyl-Peptidase IV Inhibitors Phase 4
4 HIV Protease Inhibitors Phase 4
5 Hormone Antagonists Phase 4
6 Hormones Phase 4
7 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
8 Hypoglycemic Agents Phase 4
9 Incretins Phase 4
10
protease inhibitors Phase 4
11 Sitagliptin Phosphate Phase 4
12
Coenzyme Q10 Approved, Investigational, Nutraceutical Phase 3 303-98-0 5281915
13 Tocopherol Approved, Investigational, Nutraceutical Phase 3
14
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
15 Antioxidants Phase 3
16 Micronutrients Phase 3
17 Protective Agents Phase 3
18 Tocopherols Phase 3
19 Tocotrienols Phase 3
20 Trace Elements Phase 3
21 Ubiquinone Phase 3
22 Vitamins Phase 3
23 Tocotrienol Investigational, Nutraceutical Phase 3 6829-55-6
24
Isradipine Approved, Investigational Phase 2 75695-93-1 3784
25 Antihypertensive Agents Phase 2
26 calcium channel blockers Phase 2
27 Calcium, Dietary Phase 2
28 Vasodilator Agents Phase 2
29 Acidophilus Nutraceutical

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea Completed NCT01195090 Phase 4 Sitagliptin;pioglitazone
2 Effects of Coenzyme Q10 (CoQ) in Parkinson Disease Terminated NCT00740714 Phase 3 Coenzyme Q10 with vitamin E;placebo with vitamin E
3 Safety, Tolerability and Efficacy Assessment of Dynacirc CR in Parkinson Disease Completed NCT00909545 Phase 2 Isradipine CR 5mg;Isradipine CR 10mg;Isradipine CR 20mg;Placebo
4 Impact of Handing to Patients a Copy of the Consultation Report on Their Medicine Consumption Completed NCT02237573
5 Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers Completed NCT01033799
6 Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation Terminated NCT01315418

Search NIH Clinical Center for Nasopharyngitis

Cochrane evidence based reviews: nasopharyngitis

Genetic Tests for Nasopharyngitis

Anatomical Context for Nasopharyngitis

MalaCards organs/tissues related to Nasopharyngitis:

38
Endothelial, Lymph Node, Thyroid, T Cells, Pituitary, Tonsil, Tongue

Publications for Nasopharyngitis

Articles related to Nasopharyngitis:

(show top 50) (show all 2461)
# Title Authors Year
1
Baicalin hydrate inhibits cancer progression in nasopharyngeal carcinoma by affecting genome instability and splicing. ( 29416665 )
2018
2
Patterns of vascularization and surgical morbidity in juvenile nasopharyngeal angiofibroma: A case series, systematic review, and meta-analysis. ( 29130560 )
2018
3
Endoscopic Surgery for Delayed Sinonasal Complications of Radiation Therapy for Nasopharyngeal Carcinoma: A Subjective Outcome. ( 29439883 )
2018
4
Efficacy and Safety of Nimotuzumab Plus Radiotherapy With or Without Cisplatin-Based Chemotherapy in an Elderly Patient Subgroup (Aged 60 and Older) With Nasopharyngeal Carcinoma. ( 29425953 )
2018
5
Time course and clinical characterization of cisplatin-induced ototoxicity after treatment for nasopharyngeal carcinoma in a South East Asian population. ( 29451951 )
2018
6
Prevalent somatic BRCA1 mutations shape clinically relevant genomic patterns of nasopharyngeal carcinoma in Southeast Europe. ( 28857155 )
2018
7
Endonasal endoscopic nasopharyngectomy for the treatment of nasopharyngeal papillary adenocarcinoma: Report of a rare case. ( 29287881 )
2018
8
Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma. ( 29445147 )
2018
9
Endostar Combined with Gemcitabine and Cisplatin Chemotherapy for Patients with Metastatic Nasopharyngeal Carcinoma: an Update. ( 29413761 )
2018
10
Clinical Variables for Prediction of the Therapeutic Effects of Bevacizumab Monotherapy in Nasopharyngeal Carcinoma Patients With Radiation-Induced Brain Necrosis. ( 29413276 )
2018
11
Cumulative sum analysis of the learning curve for endoscopic resection of juvenile nasopharyngeal angiofibroma. ( 29368283 )
2018
12
Induction chemotherapy plus concurrent chemoradiotherapy in endemic nasopharyngeal carcinoma: individual patient data pooled analysis of four randomized trials. ( 29431618 )
2018
13
LncRNA-LINC00460 facilitates nasopharyngeal carcinoma tumorigenesis through sponging miR-149-5p to up-regulate IL6. ( 28987345 )
2018
14
Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma. ( 29423042 )
2018
15
Early evaluation of radiation-induced parotid damage in patients with nasopharyngeal carcinoma by T2 mapping and mDIXON Quant imaging: initial findings. ( 29422068 )
2018
16
Randomized, Double-Blind, Placebo-Controlled Trial of Shuanghua Baihe Tablets to Prevent Oral Mucositis in Patients With Nasopharyngeal Cancer Undergoing Chemoradiation Therapy. ( 29353657 )
2018
17
Functions and Roles of Long-Non-Coding RNAs in Human Nasopharyngeal Carcinoma. ( 29448252 )
2018
18
miR-93 enhances cell proliferation by directly targeting CDKN1A in nasopharyngeal carcinoma. ( 29434867 )
2018
19
Characterization of the nasopharyngeal and middle ear microbiota in gastroesophageal reflux-prone versus gastroesophageal reflux non-prone children. ( 29404836 )
2018
20
Regulatory role of CDX2 and NOX4 expression associated with recurrent nasopharyngeal carcinoma. ( 29424902 )
2018
21
Long non-coding RNA n326322 promotes the proliferation and invasion in nasopharyngeal carcinoma. ( 29416735 )
2018
22
Localised nasopharyngeal amyloidosis: the importance of postoperative follow-up. ( 29444790 )
2018
23
Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma. ( 29413277 )
2018
24
Development and validation of a gene expression-based signature to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma: a retrospective, multicentre, cohort study. ( 29428165 )
2018
25
MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition. ( 29427737 )
2018
26
Predictive value of excision repair cross- complementation group 1 expression in locoregionally advanced nasopharyngeal carcinoma receiving cisplatin-based concurrent chemoradiotherapy. ( 29439312 )
2018
27
Long non-coding RNA LOC100129148 functions as an oncogene in human nasopharyngeal carcinoma by targeting miR-539-5p. ( 28328537 )
2017
28
miR-324-3p suppresses migration and invasion by targeting WNT2B in nasopharyngeal carcinoma. ( 28053597 )
2017
29
Demographic and clinicopathological characteristics of nasopharyngeal carcinoma and survival outcomes according to age at diagnosis: A population-based analysis. ( 28939081 )
2017
30
Curcumin exerts its antitumor activity through regulation of miR-7/Skp2/p21 in nasopharyngeal carcinoma cells. ( 28496336 )
2017
31
Cetuximab versus nimotuzumab for the treatment of advanced nasopharyngeal carcinoma: A network meta-analysis. ( 28952220 )
2017
32
Bortezomib Relieves Immune Tolerance in Nasopharyngeal Carcinoma via STAT1 Suppression and Indoleamine 2,3-Dioxygenase Downregulation. ( 27923823 )
2017
33
Associations of lifestyle and diet with the risk of nasopharyngeal carcinoma in Singapore: a case-control study. ( 28063457 )
2017
34
2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-I_B/HIF-1 signaling pathway inactivation and EMT reversal. ( 28000883 )
2017
35
Incidence and dosimetric parameters for brainstem necrosis following intensity modulated radiation therapy in nasopharyngeal carcinoma. ( 28939083 )
2017
36
Inhibition of fibroblast growth factor receptor with AZD4547 mitigates juvenile nasopharyngeal angiofibroma. ( 28707818 )
2017
37
Prognostic value of cervical nodal tumor volume in nasopharyngeal carcinoma: Analysis of 1230 patients with positive cervical nodal metastasis. ( 28489930 )
2017
38
Long-Term Progression of Sensorineural Hearing Loss and Tinnitus after Combined Intensity-Modulated Radiation Therapy and Cisplatin-Based Chemotherapy for Nasopharyngeal Carcinoma: A Case Report. ( 28878660 )
2017
39
Juvenile Nasopharyngeal Angiofibroma: A Case Report. ( 28571176 )
2017
40
FM807, a curcumin analogue, shows potent antitumor effects in nasopharyngeal carcinoma cells by heat shock protein 90 inhibition. ( 28157708 )
2017
41
Effects of dosimetric inadequacy on local control and toxicities in the patients with T4 nasopharyngeal carcinoma extending into the intracranial space and treated with intensity-modulated radiotherapy plus chemotherapy. ( 28931426 )
2017
42
Real-time In vivo Diagnosis of Nasopharyngeal Carcinoma Using Rapid Fiber-Optic Raman Spectroscopy. ( 28912892 )
2017
43
CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis. ( 27491320 )
2017
44
ZNRF3 Inhibits the Invasion and Tumorigenesis in Nasopharyngeal Carcinoma Cells by Inactivating the Wnt/I^-Catenin Pathway. ( 27733215 )
2017
45
Perioperative airway management of a 16-year-old boy with progressive airway obstruction due to juvenile nasopharyngeal angiofibroma. ( 28781841 )
2017
46
The FOXM1-ABCC5 axis contributes to paclitaxel resistance in nasopharyngeal carcinoma cells. ( 28277541 )
2017
47
Serum long non-coding RNAs MALAT1, AFAP1-AS1 and AL359062 as diagnostic and prognostic biomarkers for nasopharyngeal carcinoma. ( 28467811 )
2017
48
BEX3 contributes to cisplatin chemoresistance in nasopharyngeal carcinoma. ( 28083995 )
2017
49
Inactivation of HMGCL promotes proliferation and metastasis of nasopharyngeal carcinoma by suppressing oxidative stress. ( 28931870 )
2017
50
Minicircle-oriP-miR-31 as a Novel EBNA1-specific miRNA Therapy Approach for Nasopharyngeal Carcinoma. ( 28042945 )
2017

Variations for Nasopharyngitis

Expression for Nasopharyngitis

Search GEO for disease gene expression data for Nasopharyngitis.

Pathways for Nasopharyngitis

GO Terms for Nasopharyngitis

Cellular components related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 DPP4 IL17A IL17F IL17RA LTF PCSK9
2 spindle GO:0005819 9.5 ARL2BP SEPT12 SEPT6
3 midbody GO:0030496 9.43 ARL2BP SEPT12 SEPT6
4 cleavage furrow GO:0032154 9.37 SEPT12 SEPT6
5 septin complex GO:0031105 8.96 SEPT12 SEPT6
6 sperm annulus GO:0097227 8.62 SEPT12 SEPT6

Biological processes related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to fungus GO:0050832 9.37 IL17A IL17RA
2 positive regulation of interleukin-6 secretion GO:2000778 9.32 IL17A IL17F
3 positive regulation of interleukin-23 production GO:0032747 9.26 IL17A IL17RA
4 fibroblast activation GO:0072537 9.16 IL17A IL17RA
5 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.13 IL17A IL17F IL17RA
6 cellular response to interleukin-17 GO:0097398 8.8 IL17A IL17F IL17RA

Molecular functions related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.9 ARL2BP DPP4 IL17A IL17F IL17RA LRRC4
2 serine-type endopeptidase activity GO:0004252 9.13 DPP4 LTF PCSK9
3 serine-type peptidase activity GO:0008236 8.8 DPP4 LTF PCSK9

Sources for Nasopharyngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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