MCID: NSP002
MIFTS: 40

Nasopharyngitis malady

Categories: Respiratory diseases

Aliases & Classifications for Nasopharyngitis

Summaries for Nasopharyngitis

Disease Ontology : 12 A nasopharyngeal disease which involves inflammation of the nasal passages and upper part of the pharynx.

MalaCards based summary : Nasopharyngitis, also known as chronic nasopharyngitis, is related to nasopharyngeal carcinoma and nasopharyngeal carcinoma, 3. An important gene associated with Nasopharyngitis is DPP4 (Dipeptidyl Peptidase 4). The drugs Metformin and Pioglitazone have been mentioned in the context of this disorder. Affiliated tissues include endothelial, lymph node and thyroid.

Wikipedia : 71 Common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory tract... more...

Related Diseases for Nasopharyngitis

Diseases related to Nasopharyngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 232)
id Related Disease Score Top Affiliating Genes
1 nasopharyngeal carcinoma 12.4
2 nasopharyngeal carcinoma, 3 12.1
3 nasopharyngeal carcinoma 2 12.0
4 nasopharyngeal disease 12.0
5 juvenile nasopharyngeal angiofibroma 12.0
6 nasopharyngeal teratoma 11.9
7 dandy-walker malformation with nasopharyngeal teratoma and diaphragmatic hernia 11.8
8 nasopharyngeal cancer, childhood 11.7
9 common cold 11.6
10 lymphoepithelioma-like carcinoma 11.6
11 pharyngitis 11.4
12 otosalpingitis 10.8
13 chronic rhinitis 10.4
14 teratoma 10.3
15 paragonimiasis 10.1 IL17A LTF
16 endotheliitis 10.1
17 otitis media 10.0
18 adenocarcinoma 10.0
19 choanal atresia, bilateral 9.9 IL17A IL17RA
20 lymphoma 9.9
21 adenoma 9.9
22 hypoxia 9.9
23 pneumonia 9.9
24 esophagitis 9.9
25 papillary adenocarcinoma 9.9
26 primary non-gestational choriocarcinoma of ovary 9.9 IL17A IL36RN
27 influenza 9.9
28 cervicitis 9.9
29 bronchiolitis 9.9
30 motor peripheral neuropathy 9.9 IL17A IL17RA
31 thyroiditis 9.8
32 adenoiditis 9.8
33 haemophilus influenzae 9.8
34 tonsillitis 9.8
35 diphtheria 9.8
36 sinusitis 9.8
37 papilloma 9.8
38 rhinitis 9.8
39 pleomorphic adenoma 9.8
40 dermatomyositis 9.8
41 squamous cell carcinoma 9.8
42 laryngitis 9.8
43 mucoepidermoid carcinoma 9.8
44 cranial nerve palsy 9.8
45 pertussis 9.7
46 rhabdomyosarcoma 9.7
47 retinoblastoma 9.7
48 pituitary adenoma 9.7
49 actinomycosis 9.7
50 prostatitis 9.7

Graphical network of the top 20 diseases related to Nasopharyngitis:



Diseases related to Nasopharyngitis

Symptoms & Phenotypes for Nasopharyngitis

Drugs & Therapeutics for Nasopharyngitis

Drugs for Nasopharyngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 51)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 14219 4091
2
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
3 Dipeptidyl-Peptidase IV Inhibitors Phase 4
4 HIV Protease Inhibitors Phase 4
5 Hormone Antagonists Phase 4
6 Hormones Phase 4
7 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
8 Hypoglycemic Agents Phase 4
9 Incretins Phase 4
10
protease inhibitors Phase 4
11 Sitagliptin Phosphate Phase 4
12
Ephedrine Approved Phase 3 299-42-3 9294
13
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
14
Naphazoline Approved Phase 3 835-31-4 4436
15
Oxymetazoline Approved Phase 3 1491-59-4 4636
16
Phenylephrine Approved Phase 3 59-42-7 6041
17
Pseudoephedrine Approved Phase 3 90-82-4 7028
18
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
19
Maleic acid Experimental Phase 3 110-16-7 444266
20 Adrenergic Agents Phase 3
21 Adrenergic Agonists Phase 3
22 Adrenergic alpha-Agonists Phase 3
23 Anti-Allergic Agents Phase 3
24 Autonomic Agents Phase 3
25 Histamine Antagonists Phase 3
26 Histamine H1 Antagonists Phase 3
27
Histamine Phosphate Phase 3 51-74-1 65513
28 Mydriatics Phase 3
29 Nasal Decongestants Phase 3
30 Neurotransmitter Agents Phase 3
31 Peripheral Nervous System Agents Phase 3
32 Protective Agents Phase 3
33 pyrilamine Phase 3
34 Respiratory System Agents Phase 3
35 Vasoconstrictor Agents Phase 3
36 Antioxidants Phase 3
37 Micronutrients Phase 3
38 Tocopherols Phase 3
39 Tocotrienols Phase 3
40 Trace Elements Phase 3
41 Ubiquinone Phase 3
42 Vitamins Phase 3
43
Coenzyme Q10 Experimental, Nutraceutical Phase 3 303-98-0 5281915
44 Tocopherol Nutraceutical Phase 3
45 Tocotrienol Nutraceutical Phase 3
46
Isradipine Approved Phase 2 75695-93-1 3784
47 Antihypertensive Agents Phase 2
48 calcium channel blockers Phase 2
49 Calcium, Dietary Phase 2
50 Vasodilator Agents Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase
1 Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea Completed NCT01195090 Phase 4
2 Clinical Study Evaluating the Efficacy and Safety of Pediatric Drugs in Improving Nasal Congestion. Not yet recruiting NCT02601235 Phase 3
3 Effects of Coenzyme Q10 (CoQ) in Parkinson Disease Terminated NCT00740714 Phase 3
4 Safety, Tolerability and Efficacy Assessment of Dynacirc CR in Parkinson Disease Completed NCT00909545 Phase 2
5 Impact of Handing to Patients a Copy of the Consultation Report on Their Medicine Consumption Completed NCT02237573
6 Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers Completed NCT01033799
7 Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation Terminated NCT01315418

Search NIH Clinical Center for Nasopharyngitis

Cochrane evidence based reviews: nasopharyngitis

Genetic Tests for Nasopharyngitis

Anatomical Context for Nasopharyngitis

MalaCards organs/tissues related to Nasopharyngitis:

39
Endothelial, Lymph Node, Thyroid, Pituitary, T Cells, Tonsil, Tongue

Publications for Nasopharyngitis

Articles related to Nasopharyngitis:

(show top 50) (show all 2306)
id Title Authors Year
1
Long non-coding RNA LOC100129148 functions as an oncogene in human nasopharyngeal carcinoma by targeting miR-539-5p. ( 28328537 )
2017
2
Bortezomib Relieves Immune Tolerance in Nasopharyngeal Carcinoma via STAT1 Suppression and Indoleamine 2,3-Dioxygenase Downregulation. ( 27923823 )
2017
3
MicroRNA-138-5p controls sensitivity of nasopharyngeal carcinoma to radiation by targeting EIF4EBP1. ( 28075468 )
2017
4
miR-519 suppresses nasopharyngeal carcinoma cell proliferation by targeting oncogene URG4/URGCP. ( 28315691 )
2017
5
Hepatitis B virus screening and reactivation and management of patients with nasopharyngeal carcinoma: A large-scale, big-data intelligence platform-based analysis from an endemic area. ( 28493307 )
2017
6
A large-scale retrospective study of the overall survival outcome in nasopharyngeal carcinoma with hypertension in Chinese population. ( 28498819 )
2017
7
Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53-ROS-Mitochondrial Pathway. ( 28081741 )
2017
8
(18)F-FLT and (18)F-FDG PET/CT in Predicting Response to Chemoradiotherapy in Nasopharyngeal Carcinoma: Preliminary Results. ( 28091565 )
2017
9
CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis. ( 27491320 )
2017
10
Increased expression of Cks1 protein is associated with lymph node metastasis and poor prognosis in nasopharyngeal carcinoma. ( 28061788 )
2017
11
Norovirus in feces and nasopharyngeal swab of children with and without acute gastroenteritis symptoms: First report of GI.5 in Brazil and GI.3 in nasopharyngeal swab. ( 28033513 )
2017
12
Three-Phase Adaptive Radiation Therapy for Patients With Nasopharyngeal Carcinoma Undergoing Intensity-Modulated Radiation Therapy: Dosimetric Analysis. ( 28511585 )
2017
13
Curcumin exerts its antitumor activity through regulation of miR-7/Skp2/p21 in nasopharyngeal carcinoma cells. ( 28496336 )
2017
14
2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-I_B/HIF-1 signaling pathway inactivation and EMT reversal. ( 28000883 )
2017
15
Epigallocatechin-3-gallate Modulates MicroRNA Expression Profiles in Human Nasopharyngeal Carcinoma CNE2 Cells. ( 28051030 )
2017
16
Risk of hypothyroidism among patients with nasopharyngeal carcinoma treated with radiation therapy: A Population-Based Cohort Study. ( 28532605 )
2017
17
Prognostic value of cervical nodal tumor volume in nasopharyngeal carcinoma: Analysis of 1230 patients with positive cervical nodal metastasis. ( 28489930 )
2017
18
Comparison of the efficacy between intensity-modulated radiotherapy and two-dimensional conventional radiotherapy in stage II nasopharyngeal carcinoma. ( 28498818 )
2017
19
Nasopharyngeal carcinoma treated with bevacizumab combined with paclitaxel liposome plus cisplatin: a case report and literature review. ( 28053541 )
2017
20
Downregulated ECRG4 is correlated with lymph node metastasis and predicts poor outcome for nasopharyngeal carcinoma patients. ( 27119734 )
2017
21
PKCI+ promotes local advancement via its dual roles in nasopharyngeal carcinoma. ( 28084179 )
2017
22
Efficacy and safety of nimotuzumab with neoadjuvant chemotherapy followed by concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma. ( 28493838 )
2017
23
miR-324-3p suppresses migration and invasion by targeting WNT2B in nasopharyngeal carcinoma. ( 28053597 )
2017
24
Interaction between miR-572 and PPP2R2C and their effects on proliferation, migration and invasion of nasopharyngeal carcinoma (NPC) cells. ( 28525724 )
2017
25
Associations of lifestyle and diet with the risk of nasopharyngeal carcinoma in Singapore: a case-control study. ( 28063457 )
2017
26
Is pretreatment Epstein-Barr virus DNA still associated with 6-year survival outcomes in locoregionally advanced nasopharyngeal carcinoma? ( 28529609 )
2017
27
Epstein-Barr virus-encoded LMP2A stimulates migration of nasopharyngeal carcinoma cells via EGFR/Ca(2+)/calpain/ITGI^4 axis. ( 28512118 )
2017
28
Histogram analysis of diffusion kurtosis imaging of nasopharyngeal carcinoma: Correlation between quantitative parameters and clinical stage. ( 28525383 )
2017
29
Inhibition of N-acetylglucosaminyltransferase V enhances the cetuximab-induced radiosensitivity of nasopharyngeal carcinoma cells likely through EGFR N-glycan alterations. ( 28535302 )
2017
30
Knockdown of TKTL1 additively complements cisplatin-induced cytotoxicity in nasopharyngeal carcinoma cells by regulating the levels of NADPH and ribose-5-phosphate. ( 27916418 )
2017
31
Oleuropein enhances radiation sensitivity of nasopharyngeal carcinoma by downregulating PDRG1 through HIF1I+-repressed microRNA-519d. ( 28057028 )
2017
32
MiR-130a-3p inhibits the viability, proliferation, invasion, and cell cycle and promotes apoptosis of nasopharyngeal carcinoma cells by suppressing BACH2 expression. ( 28487475 )
2017
33
Laminaria Japonica Polysaccharides effectively inhibited the growth of nasopharyngeal carcinoma cells in vivo and in vitro study. ( 28501488 )
2017
34
EMP2 re-expression inhibits growth and enhances radiosensitivity in nasopharyngeal carcinoma. ( 28347228 )
2017
35
HLA-DRB1 allele polymorphism and nasopharyngeal carcinoma risk: a meta-analysis. ( 27535842 )
2017
36
BEX3 contributes to cisplatin chemoresistance in nasopharyngeal carcinoma. ( 28083995 )
2017
37
Intensity-modulated radiotherapy provides better quality of life than two-dimensional conventional radiotherapy for patients with stage II nasopharyngeal carcinoma. ( 28515352 )
2017
38
Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. ( 28240350 )
2017
39
Higher N stage and serum ferritin, but lower serum albumin levels are associated with distant metastasis and poor survival in patients with nasopharyngeal carcinoma following intensity-modulated radiotherapy. ( 28500850 )
2017
40
Targeting nasopharyngeal carcinoma by artesunate through inhibiting Akt/mTOR and inducing oxidative stress. ( 28078787 )
2017
41
Long-term Patterns of Regional Failure for Nasopharyngeal Carcinoma following Intensity-Modulated Radiation Therapy. ( 28529611 )
2017
42
Late toxicity, evolving radiotherapy techniques, and quality of life in nasopharyngeal carcinoma. ( 28070838 )
2017
43
Inactivation of parkin by promoter methylation correlated with lymph node metastasis and genomic instability in nasopharyngeal carcinoma. ( 28351314 )
2017
44
MicroRNA-212 inhibits the metastasis of nasopharyngeal carcinoma by targeting SOX4. ( 28504814 )
2017
45
Minicircle-oriP-miR-31 as a Novel EBNA1-specific miRNA Therapy Approach for Nasopharyngeal Carcinoma. ( 28042945 )
2017
46
Influence of Cervical Node Necrosis of Different Grades on the Prognosis of Nasopharyngeal Carcinoma Patients Treated with Intensity-Modulated Radiotherapy. ( 28529607 )
2017
47
Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-I_B pathway modulation. ( 26691054 )
2016
48
Neutrophil-to-lymphocyte ratio as a prognostic marker in locally advanced nasopharyngeal carcinoma: A pooled analysis of two randomised controlled trials. ( 27640138 )
2016
49
MicroRNA-124-3p inhibits the growth and metastasis of nasopharyngeal carcinoma cells by targeting STAT3. ( 26707908 )
2016
50
I^-Catenin is important for cancer stem cell generation and tumorigenic activity in nasopharyngeal carcinoma. ( 27177749 )
2016

Variations for Nasopharyngitis

Expression for Nasopharyngitis

Search GEO for disease gene expression data for Nasopharyngitis.

Pathways for Nasopharyngitis

GO Terms for Nasopharyngitis

Cellular components related to Nasopharyngitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 DPP4 IL17A IL17RA IL36RN LTF PCSK9

Biological processes related to Nasopharyngitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 regulation of insulin secretion GO:0050796 9.37 ARL2BP DPP4
2 defense response to fungus GO:0050832 9.32 IL17A IL17RA
3 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.26 IL17A IL17RA
4 positive regulation of interleukin-23 production GO:0032747 9.16 IL17A IL17RA
5 antifungal humoral response GO:0019732 8.96 IL36RN LTF
6 fibroblast activation GO:0072537 8.62 IL17A IL17RA

Molecular functions related to Nasopharyngitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 GDP binding GO:0019003 9.16 GNAT1 SEPT12
2 serine-type endopeptidase activity GO:0004252 9.13 DPP4 LTF PCSK9
3 serine-type peptidase activity GO:0008236 8.8 DPP4 LTF PCSK9

Sources for Nasopharyngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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