MCID: NSP002
MIFTS: 48

Nasopharyngitis malady

Respiratory diseases category
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Summaries for Nasopharyngitis

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Sources:
8Disease Ontology, 65Wikipedia, 33MalaCards
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Wikipedia:65 The common cold (also known as nasopharyngitis, rhinopharyngitis, acute coryza,head cold, or simply a... more...

MalaCards: Nasopharyngitis, also known as chronic nasopharyngitis, is related to juvenile nasopharyngeal angiofibroma and teratoma. An important gene associated with Nasopharyngitis is DPP4 (dipeptidyl-peptidase 4), and among its related pathways are Carbon metabolism and Pentose Phosphate Pathway. The compounds mannose 6-phosphate and gold have been mentioned in the context of this disorder. Affiliated tissues include endothelial, lymph node and pituitary.

Disease Ontology:8 A nasopharyngeal disease which involves inflammation of the nasal passages and upper part of the pharynx.

Aliases & Classifications for Nasopharyngitis

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 40NCIt, 58SNOMED-CT, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

nasopharyngitis 8 10 45 62
chronic nasopharyngitis 8 62
nasopharyngitis nos 8


External Ids:

Disease Ontology8 DOID:10460
NCIt40 C34837
MeSH35 D009304
ICD1025 J31.1

Related Diseases for Nasopharyngitis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Nasopharyngitis:



Diseases related to nasopharyngitis

Symptoms for Nasopharyngitis

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Drugs & Therapeutics for Nasopharyngitis

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42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Nasopharyngitis

Search NIH Clinical Center for Nasopharyngitis

Genetic Tests for Nasopharyngitis

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Anatomical Context for Nasopharyngitis

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33MalaCards
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MalaCards organs/tissues related to Nasopharyngitis:

33
Endothelial, Lymph node, Pituitary, T cells, Thyroid, Tonsil, Colon, Lung, Bone, Salivary gland, Tongue, B cells, Bone marrow, Prostate, Liver, Retina, Testis, Nk cells, Myeloid, Breast, Testes, Spleen, Spinal cord, Brain, Cerebellum

Animal Models for Nasopharyngitis or affiliated genes

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Publications for Nasopharyngitis

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52PubMed
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Articles related to Nasopharyngitis:

(show top 50)    (show all 1642)
idTitleAuthorsYear
1
Correlation between expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 and cervical lymph node metastasis of nasopharyngeal carcinoma. (23577575)
2013
2
Nasopharyngeal mucoepidermoid carcinoma in children. (23294931)
2013
3
STAT3 as a therapeutic target for Epstein-Barr virus (EBV): associated nasopharyngeal carcinoma. (23220625)
2013
4
Transnasal endoscopic approach with powered instrumentation for treating squamous papilloma in the nasopharyngeal surface of the soft palate. (23351477)
2013
5
Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. (23878770)
2013
6
Down-regulation of GnT-V enhances nasopharyngeal carcinoma cell CNE-2 radiosensitivity in vitro and in vivo. (22780953)
2012
7
FLJ10540 is associated with tumor progression in nasopharyngeal carcinomas and contributes to nasopharyngeal cell proliferation, and metastasis via osteopontin/CD44 pathway. (22591637)
2012
8
PinX1 regulation of telomerase activity and apoptosis in nasopharyngeal carcinoma cells. (22316341)
2012
9
Anti-angiogenic and tumor-suppressive roles of candidate tumor-suppressor gene, Fibulin-2, in nasopharyngeal carcinoma. (21743496)
2012
10
Let-7a inhibits proliferation and induces apoptosis by targeting EZH2 in nasopharyngeal carcinoma cells. (22972404)
2012
11
Bilateral non-superselective embolization with particles under transient occlusion of the internal carotid artery in the management of juvenile nasopharyngeal angiofibroma: technical note. (22903329)
2012
12
The influence of the TA1bingen soft palate plate and early cleft closure on the nasopharyngeal airway for the management of airway obstruction in an infant with Pierre Robin sequence: A case report. (23010599)
2012
13
Role of nasopharyngeal reflux in the etiology of otitis media with effusion. (22420439)
2011
14
A case report of nasopharyngeal teratoma with a cleft palate and an inguinal hernia. (21524948)
2011
15
Tumor-targeted human telomerase reverse transcriptase promoter/tk gene therapy against human nasopharyngeal carcinoma cells in vitro]. (20423828)
2010
16
The effect of transforming growth factor-beta1 on nasopharyngeal carcinoma cells: insensitive to cell growth but functional to TGF-beta/Smad pathway. (20416076)
2010
17
Third cranial nerve palsy as the presenting neuro-ophthalmic feature of nasopharyngeal carcinoma. (20182221)
2010
18
C-KIT overexpression and mutation in nasopharyngeal carcinoma cell lines and reactivity of Imatinib on these cell lines. (20109338)
2010
19
Y-Box-binding protein-1 is a promising predictive marker of radioresistance and chemoradioresistance in nasopharyngeal cancer. (18978732)
2009
20
PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survival. (19012001)
2009
21
Paraneoplastic syndromes in patients with nasopharyngeal cancer. (19111998)
2009
22
Identification of novel Epstein-Barr virus microRNA genes from nasopharyngeal carcinomas. (19144710)
2009
23
Matrine enhances the cytotoxic sensitivity of ABCG2high nasopharyngeal carcinoma cells to natural killer cells by inducing high expression of NKG2D receptor ligands]. (19620045)
2009
24
p53 and nasopharyngeal carcinoma: a Malaysian study. (19900105)
2009
25
Proteomic analysis to identify cytokeratin 18 as a novel biomarker of nasopharyngeal carcinoma. (19529960)
2009
26
Hepatocyte growth factor enhances proteolysis and invasiveness of human nasopharyngeal cancer cells through activation of PI3K and JNK. (18789327)
2008
27
The clinical significance of coexpression of cyclooxygenases-2, vascular endothelial growth factors, and epidermal growth factor receptor in nasopharyngeal carcinoma. (18758376)
2008
28
Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma. (17099870)
2007
29
Frequent allelic loss at the FRA3B site in endemic nasopharyngeal carcinoma: association with clinical features and Epstein-Barr virus infection. (17359554)
2007
30
Exercise modulates platelet-nasopharyngeal carcinoma cell aggregation and subsequent tissue factor and matrix metalloproteinase activities. (17495120)
2007
31
Cyclin D1 and p16 expression in recurrent nasopharyngeal carcinoma. (16953893)
2006
32
TSLC1 is a tumor suppressor gene associated with metastasis in nasopharyngeal carcinoma. (17018592)
2006
33
Expression of PCNA, VEGF and bFGF in endothelial cells of juvenile nasopharyngeal angiofibroma]. (17285972)
2006
34
Genetic diversity of PspA types among nasopharyngeal isolates collected during an ongoing surveillance study of children in Brazil. (16891500)
2006
35
MDM2 expression in EBV-infected nasopharyngeal carcinoma cells. (15448710)
2004
36
Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma. (12794757)
2003
37
Apoptosis and TRAF-1 cleavage in Epstein-Barr virus-positive nasopharyngeal carcinoma cells treated with doxorubicin combined with a farnesyl-transferase inhibitor. (12527335)
2003
38
Expression of BRD7-interacting proteins,BRD2 and BRD3, in nasopharyngeal carcinoma tissues]. (12600283)
2003
39
EGFR tyrosine kinase inhibitor AG1478 inhibits cell proliferation and arrests cell cycle in nasopharyngeal carcinoma cells. (11410322)
2001
40
Effect of photodynamic therapy (PDT) on the expression of pro-apoptotic protein Bak in nasopharyngeal carcinoma (NPC). (11500859)
2001
41
Epstein-Barr virus latent membrane protein 1 (EBV-LMP1) and tumor proliferation rate as predictive factors of nasopharyngeal cancer (NPC) radiation response. (10895175)
2000
42
c-myc gene inactivation during induction of nasopharyngeal carcinoma cells with retinoic acid. (11776079)
2000
43
Antibody against the Epstein-Barr virus BHRF1 protein, a homologue of Bcl-2, in patients with nasopharyngeal carcinoma. (9783682)
1998
44
New prognostic factors in nasopharyngeal carcinoma. Tumor angiogenesis and C-erbB2 expression. (8608524)
1996
45
Ultrastructural study of glycogen-rich oxyphilic adenoma of the nasopharyngeal minor salivary gland. (3927580)
1985
46
Juvenile nasopharyngeal angiofibroma. A report of seven cases. (205902)
1978
47
Hyperreactivity to cow milk in young children with pulmonary hemosiderosis and cor pulmonale secondary to nasopharyngeal obstruction. (1173819)
1975
48
Clinical and immunologic studies on fetid atrophic rhinitis (ozena) of the nasopharyngeal cavity treated with a specific vaccine. (4771981)
1973
49
Further experience in treatment of juvenile nasopharyngeal angiofibroma. (4305190)
1969
50
Juvenile nasopharyngeal angiofibroma. a theory of pathogenesis. (14442741)
1959

Variations for Nasopharyngitis

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Expression for genes affiliated with Nasopharyngitis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Nasopharyngitis

Search GEO for disease gene expression data for Nasopharyngitis.

Pathways for genes affiliated with Nasopharyngitis

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50PathCards, 30KEGG, 51PharmGKB, 38NCBI BioSystems Database, 55Reactome
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Pathways related to Nasopharyngitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
L-serine degradation38
pentose phosphate pathway (oxidative branch)38
formaldehyde oxidation II (glutathione-dependent)38
9.0TKTL2, TKTL1
2
Show member pathways
pentose phosphate pathway (non-oxidative branch)38
pentose phosphate pathway38
PRPP biosynthesis38
9.0TKTL2, TKTL1

Compounds for genes affiliated with Nasopharyngitis

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45Novoseek, 24HMDB, 11DrugBank, 51PharmGKB
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Compounds related to Nasopharyngitis according to GeneCards/GeneDecks:

(show all 16)
idCompoundScoreTop Affiliating Genes
1mannose 6-phosphate45 2410.7RECK, DPP4
2gold459.7RECK, DPP4
3carbohydrates459.6DPP4, RECK
4polysaccharide459.5DPP4, RECK
5sucrose45 24 1111.4DPP4, RECK
6D-Sedoheptulose 7-phosphate249.3TKTL2, TKTL1
7Sedoheptulose249.3TKTL2, TKTL1
8Xylulose 5-phosphate249.3TKTL2, TKTL1
9D-Erythrose 4-phosphate249.3TKTL2, TKTL1
10D-Ribose 5-phosphate249.3TKTL1, TKTL2
11D-Ribulose 5-phosphate249.3TKTL2, TKTL1
12Beta-D-Fructose 6-phosphate249.3TKTL2, TKTL1
13polyacrylamide459.2DPP4, RECK
14thiamine pyrophosphate45 2410.2TKTL2, TKTL1
15glucose458.7RECK, DPP4, TKTL1
16calcium45 51 24 1111.2TKTL2, TKTL1, DPP4, RECK

GO Terms for genes affiliated with Nasopharyngitis

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16Gene Ontology
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Molecular functions related to Nasopharyngitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transketolase activityGO:0048029.0TKTL2, TKTL1

Products for genes affiliated with Nasopharyngitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Nasopharyngitis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet