MCID: NSP001
MIFTS: 44

Nasopharynx Carcinoma malady

Cancer diseases, Respiratory diseases categories

Summaries for Nasopharynx Carcinoma

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Disease Ontology:9 A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or "throat", where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.

MalaCards based summary: Nasopharynx Carcinoma, also known as malignant neoplasm of other specified sites of nasopharynx, is related to nasopharyngeal carcinoma and cervical adenocarcinoma. An important gene associated with Nasopharynx Carcinoma is ZMYND10 (zinc finger, MYND-type containing 10), and among its related pathways are Thyroid cancer and Oncogene Induced Senescence. The compounds acnu and isoniazid have been mentioned in the context of this disorder. Affiliated tissues include the nasopharynx, brain and colon.

Aliases & Classifications for Nasopharynx Carcinoma

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Nasopharynx Carcinoma, Aliases & Descriptions:

Name: Nasopharynx Carcinoma 9 11
Malignant Neoplasm of Other Specified Sites of Nasopharynx 9 60
Primary Malignant Neoplasm of Anterior Wall of Nasopharynx 9 60
Malignant Neoplasm of Superior Wall of Nasopharynx 9 60
Malignant Tumor of Posterior Wall of Nasopharynx 9 60
Malignant Tumor of Anterior Wall of Nasopharynx 9 60
Malignant Tumor of Lateral Wall of Nasopharynx 9 60
Malignant Neoplasm of Nasopharyngeal Wall 9 60
Malignant Neoplasm of Nasopharynx 9 60
Nasopharyngeal Carcinoma 9 60
 
Malignant Neoplasm of Lateral Wall of Nasopharynx Nos 9
Malignant Neoplasm of Posterior Wall of Nasopharynx 9
Malignant Neoplasm of Anterior Wall of Nasopharynx 9
Malignant Neoplasm of Lateral Wall of Nasopharynx 9
Malignant Neoplasm of Nasopharyngeal Wall Nos 9
Malignant Neoplasm of Roof of Nasopharynx 9
Malignant Nasopharyngeal Tumor 9
Cancer of Nasopharynx 60
Nasopharynx Cancer 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Respiratory diseases


Related Diseases for Nasopharynx Carcinoma

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Diseases related to Nasopharynx Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 134)
idRelated DiseaseScoreTop Affiliating Genes
1nasopharyngeal carcinoma30.8CDH1, CD79A, CDKN2A, RASSF1, COLQ, ZMYND10
2cervical adenocarcinoma30.2RASSF1, CDKN2A
3papilloma30.0TP53, RASSF1, CDKN2A
4laryngeal squamous cell carcinoma29.9CDH1, CDKN2A, TP53
5esophageal cancer29.9CDH1, CDKN2A, TP53
6lung cancer29.8TP53, RASSF1, CDKN2A, CDH1
7adenocarcinoma29.5TP53, ZMYND10, RASSF1, CDKN2A, CDH1
8nasopharyngitis11.5
9endotheliitis10.7
10hypoxia10.5
11choroid plexus papilloma10.4TP53
12dermatomyositis10.4
13actinic keratosis10.4TP53
14cranial nerve palsy10.4
15esophagitis10.4
16retinoblastoma10.3
17lymphoepithelioma-like carcinoma10.3
18otitis media10.3
19pfeiffer syndrome10.2CD79A, PDLIM7, GOLIM4
20allergic rhinitis10.2
21hepatitis10.2
22choanal atresia10.2
23keratinizing squamous cell carcinoma10.2
24cervical adenitis10.2
25collagen disease10.2
26dermatitis10.2
27rhinitis10.2
28amyopathic dermatomyositis10.2
29dysphagia10.2
30syncope10.2
31bladder transitional cell carcinoma10.1TP53, CDH1
32oropharynx cancer10.1TP53, CDKN2A
33breast cancer10.1TP53, CDH1
34stomach cancer10.1TP53, CDH1
35ductal carcinoma in situ10.1TP53, CDH1
36li-fraumeni syndrome10.1CDKN2A, TP53
37breast ductal carcinoma10.1CDH1, TP53
38cervical squamous cell carcinoma10.1RASSF1, CDKN2A
39salivary gland adenoid cystic carcinoma10.1CDH1, RASSF1
40renal cell carcinoma10.1
41leukemia10.1
42sinusitis10.1
43myelitis10.1
44primary hyperparathyroidism10.1
45cervicitis10.1
46hyperparathyroidism10.1
47malignant peripheral nerve sheath tumor10.1
48thyroiditis10.1
49nasopharyngeal teratoma10.1
50juvenile nasopharyngeal angiofibroma10.1

Graphical network of the top 20 diseases related to Nasopharynx Carcinoma:



Diseases related to nasopharynx carcinoma

Symptoms for Nasopharynx Carcinoma

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Drugs & Therapeutics for Nasopharynx Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Nasopharynx Carcinoma

Search NIH Clinical Center for Nasopharynx Carcinoma

Genetic Tests for Nasopharynx Carcinoma

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Anatomical Context for Nasopharynx Carcinoma

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MalaCards organs/tissues related to Nasopharynx Carcinoma:

31
Brain, Colon, Thyroid, Breast

FMA organs/tissues related to Nasopharynx Carcinoma:

14
The nasopharynx

Animal Models for Nasopharynx Carcinoma or affiliated genes

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Publications for Nasopharynx Carcinoma

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Articles related to Nasopharynx Carcinoma:

(show all 16)
idTitleAuthorsYear
1
Second primary malignant peripheral nerve sheath tumor of the paranasal sinuses after nasopharynx carcinoma. (25304136)
2014
2
Diagnosis of pediatric nasopharynx carcinoma after recurrent adenoidectomy. (24392236)
2013
3
Nasopharynx carcinoma: a rare primary for bilateral breast metastasis. (22778459)
2012
4
Anesthetic considerations in a child with a diagnosis of nasopharynx carcinoma who was on radiotherapy after induction chemotherapy with mucositis toxicities. (18673311)
2008
5
Pneumocephalus in nasopharynx carcinoma. (18195505)
2008
6
Nasopharynx carcinoma complicated with pneumocephalus. (16292487)
2006
7
A microcystic adnexal carcinoma in the auditory canal 15 years after radiotherapy of a 12-year-old boy with nasopharynx carcinoma. (15925985)
2005
8
QSAR of antineoplastics IV: Hansch analysis of N-(7-indolyl)benzenesulfonamides against KB human nasopharynx carcinoma, colon 38 murine adenocarcinoma and P388 murine leukemia cell lines. (11469750)
2001
9
The use of pilocarpine hydrochloride to prevent xerostomia in a child treated with high dose radiotherapy for nasopharynx carcinoma. (9861344)
1998
10
Syndrome of inappropriate secretion of antidiuretic hormone in nasopharynx carcinoma. (9260257)
1997
11
Factors influencing adjustment of patients suffering from nasopharynx carcinoma--implications for oncology social work. (9385710)
1997
12
Nasopharynx carcinoma: choice of treatment. (7558969)
1995
13
The detection of nasopharynx carcinoma in technetium-99m (V) dimercaptosuccinic acid SPECT imaging. (8386992)
1993
14
Primary hyperparathyroidism with triple cancers consisting of renal cell carcinoma, nasopharynx carcinoma and thyroid carcinoma. (839605)
1977
15
Intramedullary cervical cord metastasis from a nasopharynx carcinoma. (4852541)
1974
16
Sensitivity to irradiation of the brain stem. Irradiation myelitis in the treatment of a nasopharynx carcinoma. (4207294)
1974

Variations for Nasopharynx Carcinoma

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Expression for genes affiliated with Nasopharynx Carcinoma

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Search GEO for disease gene expression data for Nasopharynx Carcinoma.

Pathways for genes affiliated with Nasopharynx Carcinoma

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Pathways related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8TP53, CDH1
29.8CDKN2A, TP53
3
Show member pathways
9.8TP53, CDKN2A
49.8TP53, CDKN2A
5
Show member pathways
Cell cycle36
9.5TP53, CDKN2A, CDH1
69.4HLA-A, TP53, CDKN2A
79.4CDKN2A, TP53, HLA-A
89.2TP53, RASSF1, CDH1, CDKN2A
9
Show member pathways
Signaling Pathways in Glioblastoma36
9.2CDH1, CDKN2A, RASSF1, TP53
10
Show member pathways
Wnt Signaling Pathway NetPath36
9.0CDH1, BRD7, TP53

Compounds for genes affiliated with Nasopharynx Carcinoma

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Compounds related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

(show all 40)
idCompoundScoreTop Affiliating Genes
1acnu4310.2CDKN2A, TP53
2isoniazid43 49 1212.1CDKN2A, CD79A
3hpvs4310.1CDKN2A, TP53
4aristolochic acid43 211.1CDH1, TP53
5olomoucine43 1211.0TP53, CDKN2A
6temozolomide43 1211.0CDKN2A, TP53
7sodium bisulfite4310.0CDH1, CDKN2A, RASSF1
8hmba4310.0TP53, CDKN2A
9aflatoxin b143 2411.0CDKN2A, TP53
10cytosine43 2410.9CDH1, RASSF1, CDKN2A
11bcnu439.9TP53, CDKN2A
12p00001439.9CDH1, CDKN2A
13nocodazole43 1210.9CDH1, TP53, CD79A
14depsipeptide439.9CDH1, CDKN2A, TP53
15irinotecan43 49 1211.9CDKN2A, CDH1, TP53
16thymidylate439.8TP53, CDKN2A, CDH1
17adriamycin439.8TP53, CDH1, CDKN2A
18docetaxel43 49 59 1212.8CDH1, CDKN2A, TP53
19indole-3-carbinol439.8CDH1, TP53
20egcg439.8CDKN2A, TP53, CDH1
21mg 13243 5910.8CDH1, TP53, CDKN2A
22nickel43 2410.8CDKN2A, CDH1
23azathioprine43 2 49 1212.7CD79A, CDH1, RASSF1, CDKN2A
24folate439.7CDH1, CDKN2A, RASSF1, CD79A
25methotrexate49 43 1211.7CD79A, CDH1, CDKN2A
26agar439.7CD79A, RASSF1, CDKN2A, CDH1
275-methylcytosine43 2410.6TP53, RASSF1, CDKN2A, CDH1
28o6-methylguanine439.6TP53, RASSF1, CDKN2A, CDH1
29crcs439.6CDH1, RASSF1, CDKN2A, TP53
30n acetylcysteine439.6CDH1, CD79A, CDKN2A, TP53
31paraffin439.6CDKN2A, TP53, CD79A, CDH1
32zonisamide43 49 1211.6CD79A, HLA-A
335fluorouracil439.5TP53, HLA-A, CDKN2A, CDH1
34cisplatin43 49 59 1212.5CDKN2A, RASSF1, CDH1, TP53
35alanine439.3RASSF1, CD79A, HLA-A, CDH1, CDKN2A
36estrogen439.3RASSF1, CDKN2A, CD79A, TP53, CDH1
37retinoic acid43 2410.2CD79A, CDKN2A, CDH1, RASSF1, TP53
38arginine439.2CDH1, CD79A, HLA-A, TP53, CDKN2A
39oligonucleotide439.2RASSF1, HLA-A, CDKN2A, TP53
405-aza-2deoxycytidine439.0TP53, HLA-A, ZMYND10, RASSF1, CDKN2A, CDH1

GO Terms for genes affiliated with Nasopharynx Carcinoma

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Cellular components related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nuclear bodyGO:00166049.5TP53, CDKN2A
2nucleusGO:00056347.0GOLIM4, TP53, TMEM8B, BRD7, CCDC19, PDLIM7

Biological processes related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1replicative senescenceGO:00903999.8TP53, CDKN2A
2Ras protein signal transductionGO:00072659.6CDKN2A, RASSF1, TP53
3positive regulation of cell cycle arrestGO:00711589.5CDKN2A, TP53
4cell cycle arrestGO:00070509.4CDKN2A, TP53, RASSF1
5positive regulation of transcription, DNA-templatedGO:00458938.7CDH1, BRD7, TP53, CDKN2A

Molecular functions related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MDM2/MDM4 family protein bindingGO:00973719.7CDKN2A, TP53
2p53 bindingGO:00020399.0CDKN2A, BRD7, TP53
3transcription factor bindingGO:00081349.0CDKN2A, BRD7, TP53
4protein bindingGO:00055156.3RASSF1, CDH1, HLA-A, TP53, TMEM8B, CDKN2A

Products for genes affiliated with Nasopharynx Carcinoma

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  • Antibodies
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  • Kits and Assays

Sources for Nasopharynx Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet