MCID: NSP001
MIFTS: 44

Nasopharynx Carcinoma malady

Cancer diseases, Respiratory diseases categories

Aliases & Classifications for Nasopharynx Carcinoma

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Aliases & Descriptions for Nasopharynx Carcinoma:

Name: Nasopharynx Carcinoma 8 10
Malignant Neoplasm of Other Specified Sites of Nasopharynx 8 61
Primary Malignant Neoplasm of Anterior Wall of Nasopharynx 8 61
Malignant Neoplasm of Superior Wall of Nasopharynx 8 61
Malignant Tumor of Posterior Wall of Nasopharynx 8 61
Malignant Tumor of Anterior Wall of Nasopharynx 8 61
Malignant Tumor of Lateral Wall of Nasopharynx 8 61
Malignant Neoplasm of Nasopharyngeal Wall 8 61
Malignant Neoplasm of Nasopharynx 8 61
Nasopharyngeal Carcinoma 8 61
 
Malignant Neoplasm of Lateral Wall of Nasopharynx Nos 8
Malignant Neoplasm of Posterior Wall of Nasopharynx 8
Malignant Neoplasm of Anterior Wall of Nasopharynx 8
Malignant Neoplasm of Lateral Wall of Nasopharynx 8
Malignant Neoplasm of Nasopharyngeal Wall Nos 8
Malignant Neoplasm of Roof of Nasopharynx 8
Malignant Nasopharyngeal Tumor 8
Cancer of Nasopharynx 61
Nasopharynx Cancer 8


Classifications:



Summaries for Nasopharynx Carcinoma

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Disease Ontology:8 A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or "throat", where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.

MalaCards based summary: Nasopharynx Carcinoma, also known as malignant neoplasm of other specified sites of nasopharynx, is related to nasopharyngeal carcinoma and cervical adenocarcinoma. An important gene associated with Nasopharynx Carcinoma is ZMYND10 (zinc finger, MYND-type containing 10), and among its related pathways are Thyroid cancer and Oncogene Induced Senescence. The compounds acnu and isoniazid have been mentioned in the context of this disorder. Affiliated tissues include the nasopharynx, brain and colon.

Related Diseases for Nasopharynx Carcinoma

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Diseases related to Nasopharynx Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 134)
idRelated DiseaseScoreTop Affiliating Genes
1nasopharyngeal carcinoma30.8CDH1, CD79A, CDKN2A, RASSF1, COLQ, ZMYND10
2cervical adenocarcinoma30.2RASSF1, CDKN2A
3papilloma30.0TP53, RASSF1, CDKN2A
4laryngeal squamous cell carcinoma29.9CDH1, CDKN2A, TP53
5esophageal cancer29.9CDH1, CDKN2A, TP53
6lung cancer29.8TP53, RASSF1, CDKN2A, CDH1
7adenocarcinoma29.5TP53, ZMYND10, RASSF1, CDKN2A, CDH1
8nasopharyngitis11.5
9endotheliitis10.7
10hypoxia10.5
11choroid plexus papilloma10.4TP53
12dermatomyositis10.4
13actinic keratosis10.4TP53
14cranial nerve palsy10.4
15esophagitis10.4
16retinoblastoma10.3
17lymphoepithelioma-like carcinoma10.3
18otitis media10.3
19pfeiffer syndrome10.2CD79A, PDLIM7, GOLIM4
20allergic rhinitis10.2
21hepatitis10.2
22choanal atresia10.2
23keratinizing squamous cell carcinoma10.2
24cervical adenitis10.2
25collagen disease10.2
26dermatitis10.2
27rhinitis10.2
28amyopathic dermatomyositis10.2
29dysphagia10.2
30syncope10.2
31bladder transitional cell carcinoma10.1TP53, CDH1
32oropharynx cancer10.1TP53, CDKN2A
33breast cancer10.1TP53, CDH1
34stomach cancer10.1TP53, CDH1
35ductal carcinoma in situ10.1TP53, CDH1
36li-fraumeni syndrome10.1CDKN2A, TP53
37breast ductal carcinoma10.1CDH1, TP53
38cervical squamous cell carcinoma10.1RASSF1, CDKN2A
39salivary gland adenoid cystic carcinoma10.1CDH1, RASSF1
40renal cell carcinoma10.1
41leukemia10.1
42sinusitis10.1
43myelitis10.1
44primary hyperparathyroidism10.1
45cervicitis10.1
46hyperparathyroidism10.1
47malignant peripheral nerve sheath tumor10.1
48thyroiditis10.1
49nasopharyngeal teratoma10.1
50juvenile nasopharyngeal angiofibroma10.1

Graphical network of the top 20 diseases related to Nasopharynx Carcinoma:



Diseases related to nasopharynx carcinoma

Symptoms for Nasopharynx Carcinoma

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Drugs & Therapeutics for Nasopharynx Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Nasopharynx Carcinoma

Search NIH Clinical Center for Nasopharynx Carcinoma

Genetic Tests for Nasopharynx Carcinoma

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Anatomical Context for Nasopharynx Carcinoma

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MalaCards organs/tissues related to Nasopharynx Carcinoma:

31
Brain, Colon, Thyroid, Breast

FMA organs/tissues related to Nasopharynx Carcinoma:

14
The nasopharynx

Animal Models for Nasopharynx Carcinoma or affiliated genes

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Publications for Nasopharynx Carcinoma

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Articles related to Nasopharynx Carcinoma:

(show all 16)
idTitleAuthorsYear
1
Second primary malignant peripheral nerve sheath tumor of the paranasal sinuses after nasopharynx carcinoma. (25304136)
2014
2
Diagnosis of pediatric nasopharynx carcinoma after recurrent adenoidectomy. (24392236)
2013
3
Nasopharynx carcinoma: a rare primary for bilateral breast metastasis. (22778459)
2012
4
Anesthetic considerations in a child with a diagnosis of nasopharynx carcinoma who was on radiotherapy after induction chemotherapy with mucositis toxicities. (18673311)
2008
5
Pneumocephalus in nasopharynx carcinoma. (18195505)
2008
6
Nasopharynx carcinoma complicated with pneumocephalus. (16292487)
2006
7
A microcystic adnexal carcinoma in the auditory canal 15 years after radiotherapy of a 12-year-old boy with nasopharynx carcinoma. (15925985)
2005
8
QSAR of antineoplastics IV: Hansch analysis of N-(7-indolyl)benzenesulfonamides against KB human nasopharynx carcinoma, colon 38 murine adenocarcinoma and P388 murine leukemia cell lines. (11469750)
2001
9
The use of pilocarpine hydrochloride to prevent xerostomia in a child treated with high dose radiotherapy for nasopharynx carcinoma. (9861344)
1998
10
Syndrome of inappropriate secretion of antidiuretic hormone in nasopharynx carcinoma. (9260257)
1997
11
Factors influencing adjustment of patients suffering from nasopharynx carcinoma--implications for oncology social work. (9385710)
1997
12
Nasopharynx carcinoma: choice of treatment. (7558969)
1995
13
The detection of nasopharynx carcinoma in technetium-99m (V) dimercaptosuccinic acid SPECT imaging. (8386992)
1993
14
Primary hyperparathyroidism with triple cancers consisting of renal cell carcinoma, nasopharynx carcinoma and thyroid carcinoma. (839605)
1977
15
Intramedullary cervical cord metastasis from a nasopharynx carcinoma. (4852541)
1974
16
Sensitivity to irradiation of the brain stem. Irradiation myelitis in the treatment of a nasopharynx carcinoma. (4207294)
1974

Variations for Nasopharynx Carcinoma

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Expression for genes affiliated with Nasopharynx Carcinoma

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Search GEO for disease gene expression data for Nasopharynx Carcinoma.

Pathways for genes affiliated with Nasopharynx Carcinoma

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Pathways related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8CDH1, TP53
29.8TP53, CDKN2A
39.8TP53, CDKN2A
4
Show member pathways
9.8TP53, CDKN2A
5
Show member pathways
Cell cycle36
9.5CDH1, CDKN2A, TP53
69.4CDKN2A, TP53, HLA-A
79.4CDKN2A, TP53, HLA-A
89.2TP53, RASSF1, CDKN2A, CDH1
9
Show member pathways
Signaling Pathways in Glioblastoma36
9.2CDH1, CDKN2A, RASSF1, TP53
10
Show member pathways
Wnt Signaling Pathway NetPath36
9.0CDH1, BRD7, TP53

Compounds for genes affiliated with Nasopharynx Carcinoma

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Compounds related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

(show all 40)
idCompoundScoreTop Affiliating Genes
1acnu4410.2CDKN2A, TP53
2isoniazid44 50 1112.1CDKN2A, CD79A
3hpvs4410.1CDKN2A, TP53
4aristolochic acid44 111.1CDH1, TP53
5olomoucine44 1111.0TP53, CDKN2A
6temozolomide44 1111.0CDKN2A, TP53
7sodium bisulfite4410.0CDH1, CDKN2A, RASSF1
8hmba4410.0TP53, CDKN2A
9aflatoxin b144 2411.0CDKN2A, TP53
10cytosine44 2410.9CDH1, RASSF1, CDKN2A
11bcnu449.9TP53, CDKN2A
12p00001449.9CDH1, CDKN2A
13nocodazole44 1110.9CDH1, TP53, CD79A
14depsipeptide449.9CDH1, CDKN2A, TP53
15irinotecan44 50 1111.9CDKN2A, CDH1, TP53
16thymidylate449.8TP53, CDKN2A, CDH1
17adriamycin449.8TP53, CDH1, CDKN2A
18docetaxel44 50 60 1112.8CDH1, CDKN2A, TP53
19indole-3-carbinol449.8CDH1, TP53
20egcg449.8CDKN2A, TP53, CDH1
21mg 13244 6010.8CDH1, TP53, CDKN2A
22nickel44 2410.8CDKN2A, CDH1
23azathioprine44 1 50 1112.7CD79A, CDH1, RASSF1, CDKN2A
24folate449.7CDH1, CDKN2A, RASSF1, CD79A
25methotrexate50 44 1111.7CD79A, CDH1, CDKN2A
26agar449.7CD79A, RASSF1, CDKN2A, CDH1
275-methylcytosine44 2410.6TP53, RASSF1, CDKN2A, CDH1
28o6-methylguanine449.6TP53, RASSF1, CDKN2A, CDH1
29crcs449.6CDH1, RASSF1, CDKN2A, TP53
30n acetylcysteine449.6CDH1, CD79A, CDKN2A, TP53
31paraffin449.6CDKN2A, TP53, CD79A, CDH1
32zonisamide44 50 1111.6CD79A, HLA-A
335fluorouracil449.5TP53, HLA-A, CDKN2A, CDH1
34cisplatin44 50 60 1112.5CDKN2A, RASSF1, CDH1, TP53
35alanine449.3RASSF1, CD79A, HLA-A, CDH1, CDKN2A
36estrogen449.3RASSF1, CDKN2A, CD79A, TP53, CDH1
37retinoic acid44 2410.2CD79A, CDKN2A, CDH1, RASSF1, TP53
38arginine449.2CDH1, CD79A, HLA-A, TP53, CDKN2A
39oligonucleotide449.2RASSF1, HLA-A, CDKN2A, TP53
405-aza-2deoxycytidine449.0TP53, HLA-A, ZMYND10, RASSF1, CDKN2A, CDH1

GO Terms for genes affiliated with Nasopharynx Carcinoma

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Cellular components related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nuclear bodyGO:00166049.5CDKN2A, TP53
2nucleusGO:00056347.0TP53, TMEM8B, BRD7, CCDC19, PDLIM7, RASSF1

Biological processes related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1replicative senescenceGO:00903999.8CDKN2A, TP53
2Ras protein signal transductionGO:00072659.6CDKN2A, RASSF1, TP53
3positive regulation of cell cycle arrestGO:00711589.5CDKN2A, TP53
4cell cycle arrestGO:00070509.4TP53, RASSF1, CDKN2A
5positive regulation of transcription, DNA-templatedGO:00458938.7CDH1, CDKN2A, BRD7, TP53

Molecular functions related to Nasopharynx Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MDM2/MDM4 family protein bindingGO:00973719.7CDKN2A, TP53
2p53 bindingGO:00020399.0CDKN2A, BRD7, TP53
3transcription factor bindingGO:00081349.0CDKN2A, BRD7, TP53
4protein bindingGO:00055156.3BRD7, TMEM8B, TP53, HLA-A, ZMYND10, COLQ

Sources for Nasopharynx Carcinoma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet