MCID: NTR003
MIFTS: 49

Natural Killer Cell Leukemia malady

Rare diseases, Blood diseases, Cancer diseases, Immune diseases categories

Aliases & Classifications for Natural Killer Cell Leukemia

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Sources:
9Disease Ontology, 47Orphanet, 60UMLS, 41NIH Rare Diseases, 55SNOMED-CT, 38NCIt, 26ICD10 via Orphanet, 61UMLS via Orphanet
See all sources

Natural Killer Cell Leukemia, Aliases & Descriptions:

Name: Natural Killer Cell Leukemia 9
Aggressive Nk-Cell Leukemia 9 47 60
Leukemia, Natural Killer Cell Large Granular Lymphocytic 60
Large Granular Lymphocyte Leukemia, Nk-Cell Type 9
Nk-Cell Large Granular Lymphocyte Leukemia 47
Aggressive Natural Killer Cell Leukemia 41
 
Aggressive Nk-Cell Lymphoma 47
Aggressive Nk Cell Leukemia 41
Nk-Cell Lgl Leukemia 47
Ankcl 47
Ankl 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Blood diseases, Immune diseases


Characteristics (Orphanet epidemiological data):

47
aggressive nk-cell leukemia:
Age of onset: Adult; Age of death: adult


External Ids:

Disease Ontology9 DOID:1035
NCIt38 C8647
Orphanet47 86873
SNOMED-CT55 128833001
ICD10 via Orphanet26 C91.7
UMLS via Orphanet61 C1292777

Summaries for Natural Killer Cell Leukemia

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MalaCards based summary: Natural Killer Cell Leukemia, also known as aggressive nk-cell leukemia, is related to peripheral vascular disease and vascular disease. An important gene associated with Natural Killer Cell Leukemia is B3GAT1 (beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)), and among its related pathways are Busulfan Pathway, Pharmacodynamics and IL2 signaling events mediated by PI3K. The compounds topotecan and okt3 have been mentioned in the context of this disorder. Affiliated tissues include nk cells, bone and bone marrow, and related mouse phenotypes are no phenotypic analysis and tumorigenesis.

Related Diseases for Natural Killer Cell Leukemia

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Diseases related to Natural Killer Cell Leukemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 370)
idRelated DiseaseScoreTop Affiliating Genes
1peripheral vascular disease30.8MPO, CD79A
2vascular disease30.4TP53, BCL2L1, BCL2
3tuberculosis30.0IL7, IFNG, CD79A
4leukemia29.9B3GAT1, BCL2L1, BCL2, IL7, IFNG, EPO
5rheumatoid arthritis29.6MPO, IFNG, IL7, B3GAT1, CD79A
6systemic lupus erythematosus29.6MPO, IFNG, CD79A
7melanoma28.9TP53, IL7, BCL2, BCL2L1, IFNG
8arthropathy10.7
9spasticity10.7
10synovitis10.6
11pigmented villonodular synovitis10.6
12villonodular synovitis10.6
13cerebritis10.5
14metanephric adenoma10.5B3GAT1
15cerebral palsy10.5
16hemiplegia10.5
17bronchitis10.5CD79A
18pleurisy10.5MPO
19thyroiditis10.5CD79A
20spastic cerebral palsy10.4
21synovial chondromatosis10.4
22arthritis10.4
23rhinitis10.4CD79A
24composite lymphoma10.4
25neuropathy10.4
26peripheral neuropathy10.4
27large granular lymphocyte leukemia10.4
28spastic diplegia10.4
29foot drop10.4
30charcot-marie-tooth disease10.4
31tooth disease10.4
32clubfoot10.3
33hypersensitivity vasculitis10.3MPO, CD79A
34henoch-schoenlein purpura10.3CD79A, MPO
35osteoarthritis10.3
36artery disease10.3
37pneumonia10.3CD79A, MPO
38bronchiectasis10.3CD79A, MPO
39atherosclerosis10.3
40hemarthrosis10.3
41arteriosclerosis10.3
42bullous pemphigoid10.3IL7, CD79A
43precursor b-cell acute lymphoblastic leukemia10.3MPO, IL7
44malaria10.3IFNG
45nasopharynx carcinoma10.3TP53, CD79A
46osteochondritis dissecans10.3
47ischemia10.3
48common variable immunodeficiency10.3
49hematopoietic stem cell transplantation10.3
50hemophagocytic lymphohistiocytosis10.3

Graphical network of the top 20 diseases related to Natural Killer Cell Leukemia:



Diseases related to natural killer cell leukemia

Symptoms for Natural Killer Cell Leukemia

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Drugs & Therapeutics for Natural Killer Cell Leukemia

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Drug clinical trials:

Search ClinicalTrials for Natural Killer Cell Leukemia

Search NIH Clinical Center for Natural Killer Cell Leukemia

Genetic Tests for Natural Killer Cell Leukemia

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Anatomical Context for Natural Killer Cell Leukemia

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MalaCards organs/tissues related to Natural Killer Cell Leukemia:

31
Nk cells, Bone, Bone marrow, Myeloid, T cells

Animal Models for Natural Killer Cell Leukemia or affiliated genes

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MGI Mouse Phenotypes related to Natural Killer Cell Leukemia:

35 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.3IL7, IFNG, TP53, CD79A
2MP:00020068.1BCL2L1, BCL2, IFNG, TP53
3MP:00053678.0CD79A, BCL2, IFNG, TP53
4MP:00107717.7TP53, EPO, IFNG, BCL2, BCL2L1
5MP:00053857.6EPO, BCL2, IFNG, TP53, MPO
6MP:00036317.4TP53, CD79A, B3GAT1, BCL2L1, BCL2, IFNG
7MP:00053847.3EPO, CD79A, BCL2, IFNG, BCL2L1, TP53
8MP:00053877.1BCL2, CD79A, BCL2L1, IL7, IFNG, TP53
9MP:00053766.9MPO, TP53, EPO, IFNG, BCL2, BCL2L1
10MP:00107686.8BCL2, IFNG, EPO, TP53, MPO, BCL2L1
11MP:00053976.6BCL2L1, MPO, EPO, IFNG, IL7, BCL2

Publications for Natural Killer Cell Leukemia

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Articles related to Natural Killer Cell Leukemia:

(show top 50)    (show all 60)
idTitleAuthorsYear
1
Rare aggressive natural killer cell leukemia presented with bone marrow fibrosis - a diagnostic challenge. (25126488)
2014
2
Six cases of aggressive natural killer-cell leukemia in a Chinese population. (25031771)
2014
3
Aggressive natural killer-cell leukemia: classical presentation of a rare disease. (25118753)
2014
4
Abnormal immunophenotype provides a key diagnostic marker: a report of 29 cases of de novo aggressive natural killer cell leukemia. (24524877)
2014
5
Adult aggressive natural killer cell leukemia. (23241562)
2013
6
Aggressive natural killer-cell leukemia with jaundice and spontaneous splenic rupture: a case report and review of the literature. (23510456)
2013
7
Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia. (23181473)
2013
8
A probable identical Epstein-Barr virus clone-positive composite lymphoma with aggressive natural killer-cell leukemia and cytotoxic T-cell lymphoma. (24427365)
2013
9
Anti-cancer activity of gemcitabine against natural killer cell leukemia/lymphoma. (23772641)
2013
10
Successful disease control with L-asparaginase monotherapy for aggressive natural killer cell leukemia with severe hepatic failure. (22891745)
2013
11
Aggressive natural killer cell leukemia: therapeutic potential of L-asparaginase and allogeneic hematopoietic stem cell transplantation. (22360679)
2012
12
Three cases of aggressive natural killer cell leukemia with a lethal hemorrhagic complication. (23037625)
2012
13
Collapsing glomerulopathy associated with natural killer cell leukemia: a case report and review of the literature. (21908087)
2011
14
Sustained CR of refractory aggressive natural killer cell leukemia following unrelated cord blood transplantation. (20676148)
2010
15
Frequent CD7 antigen loss in aggressive natural killer-cell leukemia: a useful diagnostic marker. (20046078)
2009
16
Epstein-Barr virus-associated proliferative disorder presenting as Hodgkin's lymphoma and developing as aggressive natural killer-cell leukemia 19 years later: a case report of composite lymphoma. (19269751)
2009
17
A case of natural killer cell leukemia misdiagnosed as tuberculous lymphadenopathy. (19571615)
2009
18
Aggressive natural killer cell leukemia: is Epstein-Barr virus negativity an indicator of a favorable prognosis? (19153474)
2008
19
Aggressive natural killer cell leukemia presenting with hemophagocytic lymphohistiocytosis. (17853464)
2008
20
Precursor natural killer cell leukemia. (17417789)
2008
21
Aggressive natural killer cell leukemia: report of a Chinese series and review of the literature. (17261497)
2007
22
Aggressive natural killer cell leukemia in a patient with common variable immunodeficiency syndrome. (16785152)
2006
23
Retroviral expression screening of oncogenes in natural killer cell leukemia. (15978945)
2005
24
Aggressive Natural Killer-Cell Leukemia: report of five cases and review of the literature. (15621755)
2004
25
Aggressive natural killer cell leukemia/lymphoma: case report, use of telesynergy and review of the literature. (15360011)
2004
26
Marked elevation of soluble fas ligand and cytokine secretion after splenectomy in aggressive natural killer cell leukemia/lymphoma. (15512819)
2004
27
Aggressive natural killer-cell leukemia revisited: large granular lymphocyte leukemia of cytotoxic NK cells. (14961041)
2004
28
Unusual lymphoma manifestations: case 1. Natural killer cell leukemia with dermal erythema and vascular epidermal growth factor production. (14752078)
2004
29
Nephrotic syndrome with crescent formation and massive IgA deposition following allogeneic bone marrow transplantation for natural killer cell leukemia/lymphoma. (12543867)
2003
30
Large granular lymphocyte leukemia and natural killer cell leukemia/lymphomas. (12943609)
2003
31
Aggressive natural killer cell leukemia: clinical features and treatment outcome. (12495907)
2002
32
Comprehensive cytogenetic study by spectral karyotyping on blastic natural killer cell leukemia/lymphoma. (11891818)
2002
33
Hypersensitivity to mosquito bites as the primary clinical manifestation of a juvenile type of Epstein-Barr virus-associated natural killer cell leukemia/lymphoma. (11568749)
2001
34
Blastic natural killer cell leukemia/lymphoma presenting as overt leukemia. (11779295)
2001
35
Long-term remission induced by corticosteroids, cyclophosphamide, and methotrexate in a patient with natural killer cell leukemia. (10696134)
2000
36
Aggressive natural killer cell leukemia/lymphoma: a comprehensive cytogenetic study by spectral karyotyping. (11043424)
2000
37
Malignant hematopoietic cell lines: in vitro models for the study of natural killer cell leukemia-lymphoma. (10803505)
2000
38
Epstein-Barr virus-infected natural killer cell leukemia. (11426629)
2000
39
Blastoid natural killer cell leukemia. (10439811)
1999
40
Interferon-gamma prevents apoptosis in Epstein-Barr virus-infected natural killer cell leukemia in an autocrine fashion. (10233902)
1999
41
Natural killer cell leukemia as a cause of peripheral neuropathy and meningitis: case report. (9710063)
1998
42
Aggressive natural killer cell leukemia: report of a case in a Caucasian boy. (9549932)
1998
43
Blastic natural killer cell leukemia/lymphoma: a clinicopathologic study. (9331296)
1997
44
Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia. (8599969)
1996
45
Acute agranular CD4-positive natural killer cell leukemia. Comprehensive clinicopathologic studies including virologic and in vitro culture with inducing agents. (7736391)
1995
46
Recognition of unusual presentation of natural killer cell leukemia. (7572992)
1995
47
Natural killer cell leukemia. An autopsy case. (7979914)
1994
48
Natural killer cell leukemia presenting with a peripheral neuropathy. (8414048)
1993
49
Cytokine levels in aggressive natural killer cell leukemia and malignant histiocytosis. (1911378)
1991
50
Hematopoiesis in patients with acute natural killer cell leukemia and large granular lymphocytosis: relationship between clinical features and hematopoietic inhibitor activity of peripheral mononuclear cells. (2806481)
1989

Variations for Natural Killer Cell Leukemia

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Expression for genes affiliated with Natural Killer Cell Leukemia

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Search GEO for disease gene expression data for Natural Killer Cell Leukemia.

Pathways for genes affiliated with Natural Killer Cell Leukemia

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Pathways related to Natural Killer Cell Leukemia according to GeneCards Suite gene sharing:

(show all 43)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Catalytic cycle of mammalian FMOs36
9.4BCL2, BCL2L1
2
Show member pathways
IL2 signaling events mediated by STAT536
9.4BCL2L1, BCL2
3
Show member pathways
9.4BCL2, BCL2L1
49.4BCL2, BCL2L1
5
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway58
9.4BCL2, BCL2L1
6
Show member pathways
9.3BCL2, IFNG
79.3IFNG, BCL2
8
Show member pathways
Development Thrombopoetin signaling via JAK STAT pathway58
9.3IFNG, BCL2L1
99.2TP53, EPO
109.1TP53, BCL2
11
Show member pathways
9.1BCL2, TP53
12
Show member pathways
9.1IL7, BCL2, BCL2L1
13
Show member pathways
EPO Receptor Signaling36
EPO signaling pathway36
9.0BCL2, EPO, BCL2L1
148.9BCL2, EPO, IFNG
15
Show member pathways
8.8BCL2L1, BCL2, IFNG
168.8IFNG, BCL2L1, BCL2
178.7BCL2L1, TP53, MPO
18
Show member pathways
Apoptosis and survival TNFR1 signaling pathway58
TWEAK Signaling Pathway36
Apoptosis Modulation by HSP7036
HIV-1 Nef- Negative effector of Fas and TNF-alpha36
8.6TP53, BCL2, BCL2L1
198.6BCL2, TP53, BCL2L1
20
Show member pathways
Development EGFR signaling via PIP358
Development PDGF signaling via MAPK cascades58
Apoptosis and survival Anti apoptotic action of membrane bound ESR158
Signaling of Hepatocyte Growth Factor Receptor36
Development EGFR signaling via small GTPases58
Development Neurotrophin family signaling58
Apoptosis and survival NGF signaling pathway58
Apoptosis and survival Role of CDK5 in neuronal death and survival58
8.6BCL2L1, TP53, BCL2
21
Show member pathways
8.6BCL2L1, BCL2, TP53
22
Show member pathways
8.6BCL2, TP53, BCL2L1
23
Show member pathways
Apoptosis and survival Apoptotic TNF family pathways58
8.6TP53, BCL2, BCL2L1
24
Show member pathways
Amyotrophic lateral sclerosis (ALS)36
8.6TP53, BCL2L1, BCL2
25
Show member pathways
8.6BCL2L1, TP53, BCL2
26
Show member pathways
Apoptosis Modulation and Signaling36
Apoptosis36
8.6BCL2L1, TP53, BCL2
278.6TP53, BCL2L1, BCL2
28
Show member pathways
8.6BCL2L1, BCL2, TP53
29
Show member pathways
8.6TP53, BCL2, BCL2L1
30
Show member pathways
Type III interferon signaling36
8.5BCL2L1, EPO, IL7, IFNG
31
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.5IFNG, BCL2, TP53
328.5BCL2, IFNG, TP53
338.5IFNG, TP53, BCL2
348.5BCL2L1, IFNG, TP53
35
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
8.4BCL2L1, MPO, BCL2, IFNG
36
Show member pathways
8.3IL7, BCL2, BCL2L1, TP53
37
Show member pathways
8.2BCL2L1, TP53, BCL2, CD79A
38
Show member pathways
8.1TP53, IFNG, BCL2, CD79A
39
Show member pathways
Proteasome Degradation36
Immune response Antigen presentation by MHC class I58
8.0TP53, IFNG, BCL2, BCL2L1
407.8TP53, EPO, IL7, BCL2, BCL2L1
41
Show member pathways
7.7IFNG, TP53, EPO, IL7, BCL2
42
Show member pathways
7.2BCL2L1, BCL2, IL7, IFNG, EPO, TP53

Compounds for genes affiliated with Natural Killer Cell Leukemia

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Compounds related to Natural Killer Cell Leukemia according to GeneCards Suite gene sharing:

(show top 50)    (show all 157)
idCompoundScoreTop Affiliating Genes
1topotecan43 1210.9EPO, BCL2L1
2okt3439.5CD79A, IL7, IFNG
3at 101599.4BCL2L1, BCL2
43-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide439.4BCL2L1, BCL2, IL7
5methylcellulose439.3EPO, IFNG, IL7
6gm-csf43 2810.2BCL2L1, EPO, IFNG
7staurosporin439.2BCL2, BCL2L1, IFNG
8mycophenolate mofetil43 49 1211.2CD79A, IFNG, EPO
910-hydroxycamptothecin439.0BCL2, TP53, BCL2L1
107-hydroxystaurosporine43 1210.0BCL2L1, BCL2, TP53
11chlorambucil43 1210.0BCL2, TP53, BCL2L1
12z-vad-fmk43 5910.0BCL2L1, BCL2, TP53
13sulindac sulfide439.0BCL2L1, TP53, BCL2
14noxa439.0TP53, BCL2, BCL2L1
15cd 437439.0TP53, BCL2, BCL2L1
16indole-3-carbinol438.9BCL2L1, BCL2, TP53
17dutp438.9TP53, BCL2L1, BCL2
18sulindac43 129.9BCL2, BCL2L1, TP53
19depsipeptide438.9TP53, BCL2L1, BCL2
20triptolide438.9BCL2, IFNG, TP53
212-methoxyestradiol43 59 2410.8BCL2, TP53, BCL2L1
22parthenolide43 29.8TP53, IFNG, BCL2L1
23histamine43 28 2410.8B3GAT1, MPO, IFNG, IL7, CD79A
24n-(4-hydroxyphenyl)retinamide438.8TP53, BCL2, BCL2L1
25cyclophosphamide43 49 1210.8TP53, MPO, BCL2, IL7
26roscovitine438.7BCL2L1, TP53, BCL2
27oxaliplatin43 49 1210.6BCL2L1, MPO, TP53
28fludarabine43 49 1210.6BCL2L1, TP53, BCL2
29phosphatidylserine43 28 1210.6BCL2, TP53, BCL2L1, CD79A
30rapamycin438.4EPO, IFNG, IL7, BCL2L1, BCL2
31suberoylanilide hydroxamic acid438.4BCL2L1, BCL2, IFNG, TP53
32pdtc438.4TP53, BCL2L1, IFNG, BCL2
33lactacystin438.4TP53, IFNG, BCL2, BCL2L1
34dexamethasone43 49 28 1211.3BCL2, IL7, IFNG, CD79A, BCL2L1
35flavopiridol43 129.3BCL2L1, BCL2, TP53
36retinoid438.3BCL2L1, IFNG, TP53, BCL2
37n acetylcysteine438.3TP53, BCL2, BCL2L1, CD79A, MPO
38paraffin438.2TP53, BCL2, CD79A, BCL2L1, MPO
39cytarabine43 49 1210.2TP53, EPO, BCL2, MPO, BCL2L1
40h2o2438.2CD79A, BCL2L1, BCL2, TP53, MPO
41cisplatin43 49 59 1211.1TP53, BCL2L1, BCL2, EPO, MPO
42melphalan43 49 1210.1EPO, IFNG, BCL2L1, CD79A, TP53
43sb 20358043 599.1TP53, IFNG, BCL2, BCL2L1
44carboplatin43 49 1210.1MPO, TP53, BCL2, IFNG, EPO
45cycloheximide438.0IL7, BCL2L1, BCL2, TP53, IFNG
465fluorouracil438.0TP53, MPO, IFNG, BCL2L1, BCL2
47estrogen438.0TP53, IL7, BCL2, BCL2L1, B3GAT1, CD79A
48butyrate437.6IFNG, EPO, TP53, MPO, BCL2, BCL2L1
49retinoic acid43 248.3IFNG, BCL2, CD79A, BCL2L1, IL7, TP53
50vegf436.9CD79A, MPO, TP53, EPO, IFNG, IL7

GO Terms for genes affiliated with Natural Killer Cell Leukemia

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Cellular components related to Natural Killer Cell Leukemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.3IL7, IFNG, EPO, MPO
2mitochondrionGO:00057398.2BCL2L1, BCL2, TP53, MPO

Biological processes related to Natural Killer Cell Leukemia according to GeneCards Suite gene sharing:

(show all 36)
idNameGO IDScoreTop Affiliating Genes
1homeostasis of number of cells within a tissueGO:00488739.9BCL2, IL7
2negative regulation of calcium ion transport into cytosolGO:00105239.9EPO, BCL2
3B cell proliferationGO:00421009.8BCL2, CD79A
4negative regulation of growth of symbiont in hostGO:00441309.8IFNG, MPO
5B cell receptor signaling pathwayGO:00508539.8BCL2, CD79A
6negative regulation of anoikisGO:020008119.8BCL2, BCL2L1
7negative regulation of autophagyGO:00105079.8BCL2L1, BCL2
8positive regulation of B cell proliferationGO:00308909.8IL7, BCL2
9regulation of mitochondrial membrane potentialGO:00518819.7BCL2, BCL2L1
10negative regulation of intrinsic apoptotic signaling pathwayGO:020012439.7BCL2L1, BCL2
11T cell lineage commitmentGO:00023609.7IL7, TP53
12response to salt stressGO:00096519.6TP53, EPO
13extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.5BCL2, BCL2L1
14B cell lineage commitmentGO:00023269.5BCL2, TP53
15ovarian follicle developmentGO:00015419.5BCL2L1, BCL2
16negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:020012409.5BCL2L1, BCL2, IL7
17cellular response to glucose starvationGO:00421499.5TP53, BCL2
18response to ischemiaGO:00029319.5TP53, BCL2
19nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:00358729.4BCL2L1, BCL2
20cell agingGO:00075699.4TP53, BCL2
21positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:019007409.4TP53, BCL2
22humoral immune responseGO:00069599.4BCL2, IL7, IFNG
23response to gamma radiationGO:00103329.4TP53, BCL2
24response to cytokineGO:00340979.3BCL2L1, BCL2
25protein import into nucleus, translocationGO:00000609.3IFNG, TP53
26T cell differentiation in thymusGO:00330779.3TP53, BCL2
27positive regulation of cell proliferationGO:00082849.2EPO, IL7, BCL2L1
28intrinsic apoptotic signaling pathway in response to DNA damageGO:00086309.1BCL2L1, BCL2
29cellular response to hypoxiaGO:00714569.0BCL2, EPO, TP53
30regulation of mitochondrial membrane permeabilityGO:00469029.0TP53, BCL2, BCL2L1
31release of cytochrome c from mitochondriaGO:00018369.0BCL2, TP53, BCL2L1
32positive regulation of intrinsic apoptotic signaling pathwayGO:020012449.0BCL2, BCL2L1, TP53
33neuron apoptotic processGO:00514029.0BCL2, TP53, BCL2L1
34intrinsic apoptotic signaling pathwayGO:00971939.0BCL2, BCL2L1, TP53
35negative regulation of apoptotic processGO:00430668.3MPO, BCL2L1, BCL2, IL7, TP53
36apoptotic processGO:00069157.9TP53, EPO, IFNG, BCL2, BCL2L1

Molecular functions related to Natural Killer Cell Leukemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1BH3 domain bindingGO:00514349.3BCL2L1, BCL2
2protein phosphatase 2A bindingGO:00517218.8BCL2, TP53
3protein heterodimerization activityGO:00469828.6BCL2L1, BCL2, TP53

Products for genes affiliated with Natural Killer Cell Leukemia

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Sources for Natural Killer Cell Leukemia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet