MCID: NCR002
MIFTS: 32

Necrobiosis Lipoidica malady

Category: Skin diseases

Aliases & Classifications for Necrobiosis Lipoidica

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Aliases & Descriptions for Necrobiosis Lipoidica:

Name: Necrobiosis Lipoidica 10 12 36 65

Classifications:



External Ids:

Disease Ontology10 DOID:3486
MeSH36 D009335
NCIt42 C34840
ICD1027 L92.1
UMLS65 C0027538

Summaries for Necrobiosis Lipoidica

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Wikipedia:68 Necrobiosis lipoidica is a necrotising skin condition that usually occurs in patients with diabetes... more...

MalaCards based summary: Necrobiosis Lipoidica is related to malaria and breast cancer. An important gene associated with Necrobiosis Lipoidica is CD163 (CD163 Molecule), and among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include skin, breast and t cells, and related mouse phenotype renal/urinary system.

Related Diseases for Necrobiosis Lipoidica

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Graphical network of the top 20 diseases related to Necrobiosis Lipoidica:



Diseases related to necrobiosis lipoidica

Symptoms for Necrobiosis Lipoidica

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Drugs & Therapeutics for Necrobiosis Lipoidica

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Necrobiosis Lipoidica


Cochrane evidence based reviews: necrobiosis lipoidica

Genetic Tests for Necrobiosis Lipoidica

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Anatomical Context for Necrobiosis Lipoidica

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MalaCards organs/tissues related to Necrobiosis Lipoidica:

33
Skin, Breast, T cells, Lung, Heart, Prostate, Thyroid

Animal Models for Necrobiosis Lipoidica or affiliated genes

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MGI Mouse Phenotypes related to Necrobiosis Lipoidica:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.4CD36, GLI1, SCARB2, TNFRSF1B

Publications for Necrobiosis Lipoidica

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Articles related to Necrobiosis Lipoidica:

(show top 50)    (show all 378)
idTitleAuthorsYear
1
Synchronous Sacrococcygeal Myxopapillary Ependymoma and Chordoma. (26464159)
2015
2
Cardiac-resynchronization therapy in patients with systolic heart failure and QRS interval a8o130 ms: insights from a meta-analysis. (25164431)
2014
3
Prognostic value of EpCAM/MUC1 mRNA-positive cells in non-small cell lung cancer patients. (24061641)
2014
4
The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis. (24045154)
2013
5
Catechol-O-methyltransferase (COMT) influences the connectivity of the prefrontal cortex at rest. (23228511)
2013
6
Glucocorticoid receptor antagonist and siRNA prevent senescence of human bone marrow mesenchymal stromal cells in vitro. (23963647)
2013
7
Correction: Adipocytokine Profile, Cytokine Levels and Foxp3 Expression in Multiple Sclerosis: a Possible Link to Susceptibility and Clinical Course of Disease. (24244236)
2013
8
Abdominal cocoon: uncommon cause of intestinal obstruction in peritoneal dialysis patient. (23223663)
2012
9
Amino-terminal enhancer of split (AES) interacts with the oncoprotein NUP98-HOXA9 and enhances its transforming ability. (21937451)
2011
10
Warfarin dosing algorithm using clinical, demographic and pharmacogenetic data from Chinese patients. (20585834)
2011
11
Effects of distance from a heavily transited avenue on asthma and atopy in a periurban shantytown in Lima, Peru. (21237505)
2011
12
Hereditary angioedema therapy: kallikrein inhibition and bradykinin receptor antagonism. (23282868)
2010
13
Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends. (20383123)
2010
14
Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma. (19832037)
2009
15
The discovery of novel experimental therapies for inflammatory arthritis. (20339519)
2009
16
Low-power laser treatment in patients with frozen shoulder: preliminary results. (18341417)
2008
17
Endothelial nitric oxide synthase gene (T-786C) polymorphism in patients with slow coronary flow. (18300744)
2008
18
On the difference between foams stabilized by surfactants and whole casein or beta-casein. comparison of foams, foam films, and liquid surfaces studies. (18324808)
2008
19
Comparison of the antiviral activity of adefovir and tenofovir on hepatitis B virus in HIV-HBV-coinfected patients. (18771054)
2008
20
Semicarbazide-sensitive amine oxidase/vascular adhesion protein 1: recent developments concerning substrates and inhibitors of a promising therapeutic target. (18691041)
2008
21
Management of advanced germ-cell tumors of the testis. (18398406)
2008
22
Severe congenital protein C deficiency: description of a new mutation and prophylactic protein C therapy and in vivo pharmacokinetics. (18376272)
2008
23
Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. (17932354)
2007
24
Systematic screening of reactive cysteine proteomes. (14760716)
2004
25
The VCAM-1 gene that encodes the vascular cell adhesion molecule is a target of the Sry-related high mobility group box gene, Sox18. (14634005)
2004
26
Characterisation of pleural inflammation occurring after primary spontaneous pneumothorax. (15219004)
2004
27
Micrometastases in sentinel nodes of gastric cancer. (12915877)
2003
28
Clouston syndrome can mimic pachyonychia congenita. (14708603)
2003
29
Homologous recombination initiated by benzene metabolites: a potential role of oxidative stress. (12604843)
2003
30
Csk regulates integrin-mediated signals: involvement of differential activation of ERK and Akt. (12670507)
2003
31
RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain. (11967128)
2002
32
Normal bone density in male pseudohermaphroditism due to 5alpha- reductase 2 deficiency. (11781593)
2001
33
Ezrin as a prognostic indicator and its relationship to tumor characteristics in uveal malignant melanoma. (11581181)
2001
34
Identification of nucleolin as a glucocorticoid receptor interacting protein. (11162542)
2001
35
Temporal relationship of generalized epileptiform discharges to spindle frequency activity in childhood absence epilepsy. (11595151)
2001
36
Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations. (10561699)
1999
37
Association of extracellular-superoxide dismutase phenotype with the endothelial constitutive nitric oxide synthase polymorphism. (9738954)
1998
38
Dysplasia epiphysealis hemimelica (Trevor's disease) of the distal radius. (9586260)
1998
39
Role of proteasomes in T cell activation and proliferation. (9551914)
1998
40
Granulocyte colony-stimulating factor as an adjunct to induction chemotherapy for adult acute lymphoblastic leukemia--a randomized phase-III study. (9226158)
1997
41
Induction of monocyte chemoattractant protein-1 in the small veins of the ischemic and reperfused canine myocardium. (9024159)
1997
42
CT-guided intraarticular corticosteroid injection into the sacroiliac joints in patients with spondyloarthropathy: indication and follow-up with contrast-enhanced MRI. (8708047)
1996
43
Multiple glucose 6-phosphate dehydrogenase-deficient variants correlate with malaria endemicity in the Vanuatu archipelago (southwestern Pacific). (7825590)
1995
44
Impotence following pelvic fracture urethral injury: incidence, aetiology and management. (7850299)
1995
45
Nature of the pH-induced conformational changes and exposure of the C-terminal region of chromogranin A. (8243650)
1993
46
F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. (1555244)
1992
47
Differential expression of c-myc and H-ras oncogenes in Barrett's epithelium. A study using colorimetric in situ hybridization. (1929785)
1991
48
Fourier transform infrared studies of active-site-methylated rhodopsin. Implications for chromophore-protein interaction, transducin activation, and the reaction pathway. (2049524)
1991
49
Pathology of amebiasis. (6938282)
1981
50
Pathogenesis of hypertensive encephalopathy. (4120370)
1973

Variations for Necrobiosis Lipoidica

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Expression for genes affiliated with Necrobiosis Lipoidica

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Search GEO for disease gene expression data for Necrobiosis Lipoidica.

Pathways for genes affiliated with Necrobiosis Lipoidica

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GO Terms for genes affiliated with Necrobiosis Lipoidica

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Biological processes related to Necrobiosis Lipoidica according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of MAPK cascadeGO:00434109.3CD36, TNFRSF1B

Sources for Necrobiosis Lipoidica

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet