MCID: NCR002
MIFTS: 29

Necrobiosis Lipoidica malady

Skin diseases category

Aliases & Classifications for Necrobiosis Lipoidica

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Summaries for Necrobiosis Lipoidica

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Wikipedia:68 Necrobiosis lipoidica is a necrotising skin condition that usually occurs in patients with diabetes... more...

MalaCards based summary: Necrobiosis Lipoidica is related to granuloma annulare and venous insufficiency. An important gene associated with Necrobiosis Lipoidica is CD163 (CD163 Molecule), and among its related pathways are IL-3 Signaling Pathway and Adipocytokine signaling pathway. Affiliated tissues include skin, pancreas and endothelial, and related mouse phenotype behavior/neurological.

Related Diseases for Necrobiosis Lipoidica

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Graphical network of the top 20 diseases related to Necrobiosis Lipoidica:



Diseases related to necrobiosis lipoidica

Symptoms for Necrobiosis Lipoidica

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Drugs & Therapeutics for Necrobiosis Lipoidica

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Necrobiosis Lipoidica


Cochrane evidence based reviews: Necrobiosis Lipoidica

Genetic Tests for Necrobiosis Lipoidica

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Anatomical Context for Necrobiosis Lipoidica

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MalaCards organs/tissues related to Necrobiosis Lipoidica:

33
Skin, Pancreas, Endothelial, Neutrophil, Thyroid, Kidney, Eye

Animal Models for Necrobiosis Lipoidica or affiliated genes

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MGI Mouse Phenotypes related to Necrobiosis Lipoidica:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053867.5ACTA1, GLI1, NUMBL, SLC2A1, TNFRSF1B

Publications for Necrobiosis Lipoidica

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Articles related to Necrobiosis Lipoidica:

(show top 50)    (show all 375)
idTitleAuthorsYear
1
Necrobiosis lipoidica associated with Hashimoto's thyroiditis and positive detection of ANA and ASMA autoantibodies. (26273437)
2015
2
Residents'corner February 2014. DeRmpath & Clinic: differential diagnosis in palisading non-infectious granulomas. Diagnosis: Case 1: Granuloma annulare. Case 2: Necrobiosis lipoidica. (24691245)
2014
3
Necrobiosis lipoidica with elastophagocytosis on an unusual location. (24786578)
2014
4
Specific features of a rare form of disseminated necrobiosis lipoidica granuloma annulare type: a case report. (25611281)
2014
5
Long-term successful healing of ulcerated necrobiosis lipoidica after topical therapy with becaplermin. (23962308)
2013
6
Treatment of pre-ulcerative necrobiosis lipoidica with infliximab. (21547338)
2011
7
Ulcerative necrobiosis lipoidica successfully treated by vacuum-assisted closure therapy. (21700546)
2011
8
Arcuate plaques of the face and scalp. Atypical necrobiosis lipoidica (ANL) of the face and scalp. (20831607)
2010
9
Significant improvement in ulcerative necrobiosis lipoidica with hydroxychloroquine. (20465710)
2010
10
Necrobiosis lipoidica in monozygotic twins. (18209185)
2008
11
Detection of spirochaetal microorganisms by focus floating microscopy in necrobiosis lipoidica in patients from central Europe. (18462358)
2008
12
Necrobiosis lipoidica. (17544959)
2007
13
Clinical and pathologic manifestations of necrobiosis lipoidica-like skin involvement in sarcoidosis. (18092383)
2007
14
Images in clinical medicine. Necrobiosis lipoidica diabeticorum. (17079756)
2006
15
Successful treatment of necrobiosis lipoidica diabeticorum with photodynamic therapy. (17178979)
2006
16
What is necrobiosis lipoidica? (15879976)
2005
17
Necrobiosis lipoidica diabeticorum. (16206686)
2005
18
Epidermoid carcinoma and perforating necrobiosis lipoidica: a rare association. (16268888)
2005
19
Generalized necrobiosis lipoidica treated with a combination of split-thickness autografting and immunomodulatory therapy. (15533073)
2004
20
Clearance of necrobiosis lipoidica with fumaric acid esters. (14657645)
2003
21
Necrobiosis lipoidica associated with KAPbner's phenomenon in a patient with diabetes. (11236227)
2001
22
Tissue-engineered dermal skin grafting in the treatment of ulcerated necrobiosis lipoidica. (11298110)
2001
23
Persistent ulcerated necrobiosis lipoidica responding to treatment with cyclosporin. (10583126)
1999
24
Necrobiosis lipoidica: treatment by hyperbaric oxygen and local corticosteroids. (9592641)
1998
25
Necrobiosis lipoidica-like skin lesions in systemic sarcoidosis. (9830264)
1998
26
Necrobiosis lipoidica diabeticorum and thyroid disease. (9372361)
1997
27
Necrobiosis lipoidica in a diabetic intravenous drug user. (9341590)
1997
28
Necrobiosis lipoidica mimicking cellulitis. (20944321)
1997
29
Endothelin-1 expression is not altered in necrobiosis lipoidica and granuloma annulare. (8011514)
1994
30
Ulceration in necrobiosis lipoidica--a case report and study. (8403479)
1993
31
Ulcerating necrobiosis lipoidica effectively treated with pentoxifylline. (8440063)
1993
32
Familial non-diabetic necrobiosis lipoidica. (1445090)
1992
33
A new histopathologic feature of necrobiosis lipoidica diabeticorum: lymphoid nodules. (3372792)
1988
34
Pentoxifylline for necrobiosis lipoidica diabeticorum. (3624574)
1987
35
Successful treatment of ulcerated necrobiosis: lipoidica diabeticorum with prostaglandin E1 and skin flap transfer--a case report. (3914497)
1985
36
Squamous cell carcinoma arising in long-standing necrobiosis lipoidica. (3966816)
1985
37
Necrobiosis lipoidica: treatment with porcine dressings, split-thickness skin grafts and pressure garments. A case report and review of treatment modalities. (3904539)
1985
38
Direct immunofluorescence studies in granuloma annulare, necrobiosis lipoidica and granulomatosis disciformis Miescher. (381068)
1979
39
Granuloma annulare, rheumatoid nodules and necrobiosis lipoidica. (884054)
1977
40
Proceedings: Necrobiosis lipoidica diabeticorum disseminata. (4811828)
1974
41
Capillaroscopic changes in the course of necrobiosis lipoidica. (5782165)
1969
42
Atypical forms of necrobiosis lipoidica diabeticorum. A report of three cases. (5905217)
1966
43
Necrobiosis lipoidica granulomatosis. Necrobiosis lipoidica diabeticorum in the nondiabetic. (13742950)
1960
44
Scirrhous Metastasis Simulating Necrobiosis Lipoidica. (19993878)
1956
45
Necrobiosis lipoidica diabeticorum with intercapillary glomerulosclerosis. (14360798)
1955
46
Necrobiosis lipoidica. (13269650)
1955
47
Necrobiosis lipoidica diabeticorum following pyoderma. (18208051)
1948
48
Necrobiosis lipoidica diabeticorum. (18100968)
1948
49
Necrobiosis lipoidica without diabetes. (21065490)
1945
50
Necrobiosis Lipoidica Diabeticorum. (19991166)
1937

Variations for Necrobiosis Lipoidica

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Expression for genes affiliated with Necrobiosis Lipoidica

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Search GEO for disease gene expression data for Necrobiosis Lipoidica.

Pathways for genes affiliated with Necrobiosis Lipoidica

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Pathways related to Necrobiosis Lipoidica according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3SLC2A1, TNFRSF1B
29.3SLC2A1, TNFRSF1B
3
Show member pathways
9.3SLC2A1, TNFRSF1B

GO Terms for genes affiliated with Necrobiosis Lipoidica

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Cellular components related to Necrobiosis Lipoidica according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725629.1ACTA1, SLC2A1

Sources for Necrobiosis Lipoidica

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet