Aliases & Classifications for Necrotizing Fasciitis

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Aliases & Descriptions for Necrotizing Fasciitis:

Name: Necrotizing Fasciitis 11 46 13 2 66
 
Fasciitis, Necrotizing 37

Classifications:



External Ids:

Disease Ontology11 DOID:9602
ICD1028 M72.6
ICD9CM30 728.86
SNOMED-CT60 186428007, 52486002
MeSH37 D019115
NCIt43 C84916

Summaries for Necrotizing Fasciitis

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NIH Rare Diseases:46 Necrotizing fasciitis is a serious infection of the skin, the tissue just beneath the skin (subcutaneous tissue), and the tissue that covers internal organs (fascia). necrotizing fasciitis can be caused by several different types of bacteria, and the infection can arise suddenly and spread quickly. early signs include flu-like symptoms and redness and pain around the infection site. a prompt diagnosis and treatment are essential. if the infection is not treated promptly, it can lead to multiple organ failure and death. treatment typically includes intravenous (iv) antibiotics and surgery to remove infected and dead tissue. last updated: 4/12/2016

MalaCards based summary: Necrotizing Fasciitis, also known as fasciitis, necrotizing, is related to bullous pemphigoid and pharyngitis, and has symptoms including spasm and generalized muscle weakness. An important gene associated with Necrotizing Fasciitis is CD46 (CD46 Molecule), and among its related pathways are TSLP Signaling Pathway and Validated transcriptional targets of AP1 family members Fra1 and Fra2. Affiliated tissues include skin, eye and colon, and related mouse phenotype cardiovascular system.

CDC:2 Group A Streptococcus (group A strep) is a bacterium that can cause many different infections, including strep throat, scarlet fever, impetigo, and others. The bacteria live in the nose and throat. When someone who is infected coughs or sneezes, the bacteria travel in small droplets of water called respiratory droplets. One of the ways you can get sick is if you breathe in those droplets or if you touch something that has the droplets on it and then touch your mouth, nose, or eyes.

Wikipedia:69 Necrotising fasciitis (NF), commonly known as flesh-eating disease, is an infection that results in the... more...

Related Diseases for Necrotizing Fasciitis

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Diseases related to Necrotizing Fasciitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 239)
idRelated DiseaseScoreTop Affiliating Genes
1bullous pemphigoid30.4IL6, MYOM2
2pharyngitis30.1IL1RN, IL2
3systemic lupus erythematosus29.9IL18, IL2, IL6, LTA
4rheumatoid arthritis29.1CXCL8, IL18, IL1RN, IL2, IL6
5fasciitis11.1
6fournier gangrene10.7
7prostate calculus10.6CXCL8, IL18
8cervical incompetence10.6CXCL8, IL18
9corneal deposit10.6CXCL8, IL6
10tarsal tunnel syndrome10.6CXCL8, IL6
11anterior dislocation of lens10.6CXCL8, IL6
12retinal vascular disease10.6CXCL8, IL6
13benign adult familial myoclonic epilepsy10.6CXCL8, IL6
14acute posterior multifocal placoid pigment epitheliopathy10.6CXCL8, IL6
15infancy electroclinical syndrome10.6CXCL8, IL6
16shwartzman phenomenon10.6CXCL8, IL2
17arteriolosclerosis10.6IL18, IL6
18skin disease10.6CXCL8, IL6
19pasteurellosis10.6CXCL8, IL6
20cervicitis10.6
21subglottis neoplasm10.6CXCL8, IL6
22sterility due to immotile flagella10.6IL18, IL6
23osteogenesis imperfecta, type x10.6CXCL8, IL6
24syphilitic encephalitis10.6IL18, IL6
25fallopian tube disease10.6CXCL8, IL2
26gasserian ganglion meningioma10.6CXCL8, IL6
27addison's disease10.5CXCL8, IL2
28marchiafava bignami disease10.5CXCL8, IL6
29renal cell carcinoma 410.5IL18, IL6
30inflammatory spondylopathy10.5CXCL8, IL6
31ocular cancer10.5CXCL8, IL6
32human monocytic ehrlichiosis10.5IL18, IL6
33orbital lymphangioma10.5CXCL8, IL6
34amyotrophic lateral sclerosis type 410.5CXCL8, IL2
35splenic manifestation of prolymphocytic leukemia10.5IL2, IL6
36paraneoplastic polyneuropathy10.5CXCL8, IL6
37tonsillar fossa cancer10.5CXCL8, IL6
38benign fibrous mesothelioma10.5CXCL8, IL2
39mechanical lagophthalmos10.5CXCL8, IL6
40hemometra10.5IL6, LTA
41kallmann syndrome 410.5IL2, LTA
42silo filler's disease10.5IL18, IL1RN
43abducens nerve neoplasm10.5CXCL8, IL6
44temporal arteritis10.5CD46, MYOM2
45vertebral artery insufficiency10.5IL18, IL6
46spinal polio10.5CD46, IL2
47carbon baby syndrome10.4IL1RN, IL6
48atrophic vulva10.4IL1RN, IL6
49accessory nerve disease10.4CXCL8, IL6
50parasitic protozoa infectious disease10.4IL18, IL2

Graphical network of the top 20 diseases related to Necrotizing Fasciitis:



Diseases related to necrotizing fasciitis

Symptoms for Necrotizing Fasciitis

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UMLS symptoms related to Necrotizing Fasciitis:


spasm, generalized muscle weakness

Drugs & Therapeutics for Necrotizing Fasciitis

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Drugs for Necrotizing Fasciitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Carbon monoxidePhase 1108630-08-0281
Synonyms:
CO
 
Carbon monoxide
Carboneum oxygenisatum
carbon(II) oxide
2
Azithromycin33083905-01-555185, 53477736, 447043
Synonyms:
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*
121470-24-4
75199_FLUKA
83905-01-5
9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A
AC-16014
AC1L9KEG
Aritromicina
Azasite
Azenil
Azifast
Azigram
Azimakrol
Azithramycine
Azithromycin
Azithromycin & Tumor Necrosis Factor
Azithromycin (AIDS Initiative)
Azithromycin (anhydrous)
Azithromycin Dihydrate
Azithromycin Monohydrate
Azithromycin Sterile
Azithromycin dihydrate
Azithromycin plus Tumor Necrosis Factor
Azithromycine
Azithromycine [French]
Azithromycinum
Azithromycinum [Latin]
Azitrocin
Azitromax
Azitromicina
Azitromicina [Spanish]
Azitromin
Azythromycin
BIDD:GT0792
BRN 5387583
BSPBio_002285
Bio-0676
C38H72N2O12
CCRIS 1961
CHEBI:2955
CHEMBL529
CID447043
CP-62993
CP62,993
CPD000471864
DCH3
DRG-0104
 
DivK1c_000233
HMS1922G12
HMS2094M11
HMS500L15
HSDB 7205
Hemomycin
IDI1_000233
KBio1_000233
KBio2_000787
KBio2_003355
KBio2_005923
KBio3_001505
KBioGR_000731
KBioSS_000787
LS-1834
MLS001055353
MLS001066331
MLS001201763
MLS001304005
MLS001332499
MLS001332500
Misultina
MolPort-002-507-426
N,N-Dimethyl-4-amino-benzaldehyde
NCGC00090753-01
NCGC00090753-02
NINDS_000233
NSC643732
SAM002589961
SMR000471864
SPBio_001544
SPECTRUM1503679
Spectrum2_001582
Spectrum3_000653
Spectrum4_000186
Spectrum5_001867
Spectrum_000307
Sumamed
Tromix
UNII-JTE4MNN1MD
XZ-450
Z-Pak
ZIT
Zentavion
Zithromac
Zithromax
Zithromax IV
Zithromycin
Zitromax
Zitromax Avium 600
Zmas
Zmax
azithromycin
3
daptomycin84103060-53-316129629
Synonyms:
103060-53-3
AKOS005146218
C12013
C72H101N17O26
CHEBI:600103
CHEMBL508162
Cidecin
Cubicin
Cubicin (TN)
D01080
DAPTOMYCIN
Dapcin
Daptomicina
Daptomicina [Spanish]
Daptomycin (JAN/USAN/INN)
Daptomycin [USAN:INN:BAN]
Daptomycine
 
Daptomycine [French]
Daptomycinum
Daptomycinum [Latin]
Deptomycin
LS-171846
LY 146032
LY-146032
LY146032
MK-3009
MolPort-003-846-138
N-Decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine epsilon1-lactone
N-decanoyl-L-tryptophyl-D-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine 1.13-3.4-lactone
N-decanoyl-L-tryptophyl-D-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine epsilon(1)-lactone
N-decanoyl-L-tryptophyl-D-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]-L-alpha-asparagine
N-decanoyl-L-tryptophyl-L-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-ox
N-decanoyl-L-tryptophyl-L-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]-L-alpha-asparagine
UNII-NWQ5N31VKK
daptomycin
nchembio.184-comp5

Interventional clinical trials:

(show all 19)
idNameStatusNCT IDPhase
1Negative Pressure Wound Therapy With the Engenex™-Pump and Bio-Dome™ Dressing, an EvaluationRecruitingNCT01107821Phase 4
2Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue InfectionsRecruitingNCT02469857Phase 3
3Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled TrialCompletedNCT02111161Phase 2
4A Clinical Trial of the Clinical Effects of Hyperbaric Oxygen Therapy in Thai Autistic ChildrenCompletedNCT00670891Phase 1
5Exploratory Study of Raised Serum Lactate as a Marker of Necrotizing FasciitisCompletedNCT01739959
6Klebsiella Pneumoniae Necrotizing Fasciitis: Clinical and Microbiological FeaturesCompletedNCT01139112
7Outcome and Related Factors of Necrotizing Fasciitis of the LimbCompletedNCT00538577
8Daptomycin for the Treatment of Severe Necrotizing Soft-Tissue InfectionsCompletedNCT00261807
9Biomarkers in Patients With Flesh-eating Bacterial InfectionsCompletedNCT02180906
10Long Term Follow-up of Patients With Group A Streptococcal Infection Originating From the Genital TractCompletedNCT00299663
11Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean InfectionCompletedNCT01235546
12Factors Associated With Complications of Cervical Necrotizing FasciitisRecruitingNCT02847234
13Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).RecruitingNCT01790698
14Genetic Susceptibility to Severe Streptococcal InfectionsRecruitingNCT01911572
15Modulation of Biomarkers in Patients With Flesh-eating Bacterial Infections After With Hyperbaric Oxygen TreatmentRecruitingNCT02501382
16Severe Soft Tissue Infections: Perspectives of Patients and Significant OthersRecruitingNCT02169128
17Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus InfectionsRecruitingNCT01731483
18Hyperglycemia in Surgical InfectionsTerminatedNCT00353275
19Chlorhexidine Versus Betadine in Preventing Colonization of Femoral Nerve Catheters After Total Joint Arthroplasty (TJA)WithdrawnNCT00896402

Search NIH Clinical Center for Necrotizing Fasciitis


Cochrane evidence based reviews: fasciitis, necrotizing

Genetic Tests for Necrotizing Fasciitis

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Anatomical Context for Necrotizing Fasciitis

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MalaCards organs/tissues related to Necrotizing Fasciitis:

34
Skin, Eye, Colon, Breast, Liver, Kidney, Tonsil

Animal Models for Necrotizing Fasciitis or affiliated genes

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MGI Mouse Phenotypes related to Necrotizing Fasciitis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.0CCNF, CD46, IL18, IL1RN, IL2, IL6

Publications for Necrotizing Fasciitis

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Articles related to Necrotizing Fasciitis:

(show top 50)    (show all 654)
idTitleAuthorsYear
1
A case of labio-facial necrotizing fasciitis complicating acne. (27107717)
2016
2
Necrotizing fasciitis in patients with head and neck cancer. (25721060)
2015
3
Necrotizing Fasciitis of the Chest Wall: Report of Pediatric Cases. (25899752)
2015
4
Cervical necrotizing fasciitis as a complication of acute epiglottitis managed with minimally aggressive surgical intervention: Case report. (26214679)
2015
5
A fatal case of multidrug resistant acinetobacter necrotizing fasciitis: the changing scary face of nosocomial infection. (25349748)
2014
6
Bilateral Necrotizing Fasciitis around the Hips Differentiated from Fournier Gangrene: A Case Report. (27536594)
2014
7
Facial necrotizing fasciitis. (23859680)
2013
8
Necrotizing fasciitis in patients who underwent renal transplantation. (23972528)
2013
9
Early necrotizing fasciitis or isolated subcutaneous emphysema? (23358045)
2013
10
Ludwig angina progressing to fatal necrotizing fasciitis. (23532644)
2013
11
Multidisciplinary intensive care in extensive necrotizing fasciitis. (23104255)
2013
12
Appendiceal diverticulitis in a femoral hernia causing necrotizing fasciitis of the right inguinal region: report of a unique case. (21541716)
2013
13
Necrotizing fasciitis of the lower extremity caused by Shewanella algae. (23451727)
2013
14
Necrotizing fasciitis caused by a primary appendicocutaneous fistula. (22318638)
2012
15
Cervicofacial necrotizing fasciitis following periodontal abscess. (22782044)
2012
16
Klebsiella pneumoniae cervical necrotizing fasciitis originating as an abscess. (22809880)
2012
17
Life-threatening necrotizing fasciitis due to 'bath salts' injection. (22229605)
2012
18
Factors associated with the mediastinal spread of cervical necrotizing fasciitis. (22115335)
2012
19
Necrotizing Fasciitis of the Cervical Region following Extravasation Injury. (23251188)
2012
20
Monomicrobial Pseudomonas necrotizing fasciitis: a case of infection by two strains and a review of 37 cases in the literature. (22126406)
2012
21
Necrotizing fasciitis caused by methicillin-resistant Staphylococcus pseudintermedius at a previously irradiated site in a dog. (23633717)
2012
22
Necrotizing Fasciitis Associated with Staphylococcus lugdunensis. (22675644)
2012
23
Necrotizing fasciitis of thigh associated with Escherichia coli bacteremia in a patient on chronic hemodialysis. (22304536)
2012
24
Diagnosis and management of necrotizing fasciitis. (21410101)
2011
25
Necrotizing fasciitis: an unusual presentation. (23024950)
2011
26
Necrotizing fasciitis of the breast: a case managed without mastectomy. (21986017)
2011
27
Necrotizing fasciitis of the head and neck. (20848400)
2010
28
Adapting a Vacuum Assisted Closure dressing to challenging wounds: negative pressure treatment for perineal necrotizing fasciitis with rectal prolapse in a newborn affected by acute myeloid leukaemia. (20406723)
2010
29
Long-term outcomes of patients with necrotizing fasciitis. (20061842)
2010
30
Extended retroperitoneal necrotizing fasciitis with genital involvement, resembling fournier gangrene. (20583955)
2010
31
The reconstructive ladder in necrotizing fasciitis of the chest wall. (20185854)
2010
32
Periorbital necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus periorbital necrotizing fasciitis. (20704488)
2010
33
Community-acquired methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a healthy adolescent male. (20957926)
2010
34
Necrotizing fasciitis due to an infected urachal cyst in an adult. (20818312)
2010
35
Necrotizing fasciitis in a patient treated with etanercept for dermatomyositis. (18795294)
2009
36
Necrotizing fasciitis caused by Cryptococcus neoformans in a patient with pemphigus vegetans. (19663839)
2009
37
Marine bacteria as a leading cause of necrotizing fasciitis in coastal areas of South Korea. (19346393)
2009
38
Necrotizing fasciitis. Case report. (19093634)
2008
39
Severe necrotizing fasciitis complicating odontogenic nfection: a case report. (18605530)
2008
40
A case of necrotizing fasciitis due to Streptococcus agalactiae, Arcanobacterium haemolyticum, and Finegoldia magna in a dog-bitten patient with diabetes. (18594170)
2008
41
Case cluster of necrotizing fasciitis and cellulitis associated with vein sclerotherapy. (18258105)
2008
42
Necrotizing fasciitis and sepsis caused by Aeromonas hydrophila after crush injury of the lower extremity. (18687029)
2008
43
Periocular necrotizing fasciitis associated with kerato-conjunctivitis and treated with medical management: a case report. (18417825)
2008
44
Necrotizing fasciitis and gangrene associated with topical herbs in an infant. (17901041)
2007
45
Necrotizing fasciitis: strategies for diagnosis and management. (17683625)
2007
46
Cervical necrotizing fasciitis in an uncontrolled type II diabetic patient. (18603881)
2006
47
Streptococcal necrotizing fasciitis with toxic shock syndrome following cervical adenitis. (15302155)
2004
48
Report of 2 fatal cases of adult necrotizing fasciitis and toxic shock syndrome caused by Streptococcus agalactiae. (11049806)
2000
49
Update on canine streptococcal toxic shock syndrome and necrotizing fasciitis. (9105725)
1997
50
Surgical implications of necrotizing fasciitis in children with chickenpox. (8863250)
1996

Variations for Necrotizing Fasciitis

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Expression for genes affiliated with Necrotizing Fasciitis

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Search GEO for disease gene expression data for Necrotizing Fasciitis.

Pathways for genes affiliated with Necrotizing Fasciitis

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Pathways related to Necrotizing Fasciitis according to GeneCards Suite gene sharing:

(show all 25)
idSuper pathwaysScoreTop Affiliating Genes
19.8CXCL8, IL6
29.8CXCL8, IL6
39.8IL18, IL6
49.6IL2, IL6
59.6IL18, IL2
6
Show member pathways
9.4CXCL8, IL18, IL6
79.4CXCL8, IL18, IL6
89.4CXCL8, IL18, IL6
99.4CXCL8, IL18, IL6
10
Show member pathways
9.4CXCL8, IL18, IL6
119.3IL2, LTA
129.3CXCL8, IL2, IL6
139.3CXCL8, IL2, IL6
149.3CXCL8, IL2, IL6
15
Show member pathways
9.0CXCL8, IL2, LTA
169.0CXCL8, IL1RN, IL6
179.0IL18, IL2, LTA
18
Show member pathways
8.9CXCL8, IL18, IL2, IL6
19
Show member pathways
8.6IL18, IL2, IL6, LTA
20
Show member pathways
8.6IL18, IL2, IL6, LTA
21
Show member pathways
8.6CXCL8, IL18, IL1RN, IL6
228.3CXCL8, IL18, IL2, IL6, LTA
23
Show member pathways
8.3CXCL8, IL18, IL2, IL6, LTA
24
Show member pathways
8.3CXCL8, IL18, IL2, IL6, LTA
25
Show member pathways
8.0CD46, CXCL8, IL18, IL2, IL6, LTA

GO Terms for genes affiliated with Necrotizing Fasciitis

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Cellular components related to Necrotizing Fasciitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056157.5CXCL8, IL18, IL1RN, IL2, IL6, LTA

Biological processes related to Necrotizing Fasciitis according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of tissue remodelingGO:003410510.2IL18, IL2
2positive regulation of interleukin-17 productionGO:003274010.2IL18, IL2
3positive regulation of immunoglobulin secretionGO:005102410.2IL2, IL6
4positive regulation of tyrosine phosphorylation of Stat3 proteinGO:004251710.1IL18, IL6
5natural killer cell activationGO:003010110.1IL18, IL2
6positive regulation of regulatory T cell differentiationGO:004559110.1CD46, IL2
7positive regulation of activated T cell proliferationGO:004210410.1IL18, IL2
8positive regulation of interferon-gamma productionGO:00327299.5IL18, IL2, LTA
9positive regulation of T cell proliferationGO:00421029.0CD46, IL2, IL6
10immune responseGO:00069558.4CXCL8, IL18, IL1RN, IL2

Molecular functions related to Necrotizing Fasciitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051257.8IL18, IL1RN, IL2, IL6, LTA

Sources for Necrotizing Fasciitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet