MCID: NCR001
MIFTS: 38

Necrotizing Ulcerative Gingivitis

Categories: Rare diseases, Oral diseases

Aliases & Classifications for Necrotizing Ulcerative Gingivitis

MalaCards integrated aliases for Necrotizing Ulcerative Gingivitis:

Name: Necrotizing Ulcerative Gingivitis 12 14 69
Acute Necrotizing Ulcerative Gingivitis 12 72 49
Vincent's Disease 12 69
Vincent Angina 12 69
Anug 12 49
Acute Necrotising Ulcerative Gingivostomatitis [ambiguous] 12
Acute Necrotising Ulcerative Gingivitis [ambiguous] 12
Acute Necrotising Ulcerative Gingivostomatitis 12
Acute Necrotizing Ulcerative Gingivostomatitis 12
Acute Necrotising Ulcerative Gingivitis 12
Early Acute Necrotising Gingivitis 12
Gingivitis, Necrotizing Ulcerative 41
Acute Ulceromembranous Gingivitis 12
Vincent's Angina - Pharyngitis 12
Vincent's Infection, Any Site 12
Acute Membranous Gingivitis 49
Fusospirillary Gingivitis 49
Phagedenic Gingivitis 49
Vincent's Angina Nos 12
Vincent's Gingivitis 49
Vincent's Stomatitis 49
Vincent's Infection 49
Angina - Vincents 12
Vincent's Angina 12
Fusospirillosis 49
Trench Mouth 12

Classifications:



Summaries for Necrotizing Ulcerative Gingivitis

MalaCards based summary : Necrotizing Ulcerative Gingivitis, also known as acute necrotizing ulcerative gingivitis, is related to systemic lupus erythematosus and gingivitis. An important gene associated with Necrotizing Ulcerative Gingivitis is GUSB (Glucuronidase Beta), and among its related pathways/superpathways are Staphylococcus aureus infection and B Cell Development Pathways. Affiliated tissues include bone, and related phenotypes are hematopoietic system and immune system

Wikipedia : 72 Acute necrotizing ulcerative gingivitis (ANUG; colloquially known as trench mouth) is a common,... more...

Related Diseases for Necrotizing Ulcerative Gingivitis

Diseases related to Necrotizing Ulcerative Gingivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
# Related Disease Score Top Affiliating Genes
1 systemic lupus erythematosus 28.4 CD40LG CFB IL10 IL18
2 gingivitis 10.8
3 mucolipidosis iii alpha/beta 10.3 BSG GUSB
4 acalculous cholecystitis 10.3 CD40LG GUSB
5 bronchopneumonia 10.3 CD40LG GUSB
6 periodontitis 10.2
7 periodontosis 10.1 CD40LG PTGES
8 schnitzler syndrome 10.1 CD40LG IL18
9 multifocal choroiditis 10.1 CFB IL10
10 severe acute respiratory syndrome 10.1 CD40LG CTRL
11 choroiditis 10.1 CFB IL10
12 bacteriuria 10.0 CD40LG IL18
13 chikungunya 10.0 CD40LG IL18
14 cutaneous lupus erythematosus 10.0 CD40LG IL18
15 leukemia 10.0
16 ross river fever 9.9 CD40LG IL10
17 immunoglobulin a deficiency 1 9.9 CD40LG IL10
18 sporotrichosis 9.9 CD40LG IL10
19 buruli ulcer 9.9 CD40LG IL10
20 taeniasis 9.9 CD40LG IL10
21 primary systemic mycosis 9.9 CD40LG IL10
22 cystic echinococcosis 9.9 CD40LG IL10
23 coccidiosis 9.9 CD40LG IL10
24 hemorrhagic fever 9.9 CD40LG IL10
25 panuveitis 9.9 CD40LG IL10
26 scrub typhus 9.9 CD40LG IL10
27 plasmodium vivax malaria 9.9 CD40LG IL10
28 q fever 9.9 CD40LG IL10
29 churg-strauss syndrome 9.9 CD40LG IL10
30 hemorrhagic fever with renal syndrome 9.9 CD40LG IL10
31 extrinsic cardiomyopathy 9.9 CD40LG IL10
32 opportunistic mycosis 9.8 CD40LG IL10
33 cow milk allergy 9.8 IL10 IL18
34 idiopathic neutropenia 9.8 CD40LG IL10
35 blood group, i system 9.8
36 bacteremia 2 9.8
37 acute lymphocytic leukemia 9.8
38 von willebrand's disease 9.8
39 bruxism 9.8
40 lupus erythematosus 9.8
41 stomatitis 9.8
42 noma 9.8
43 mixed connective tissue disease 9.8 CD40LG IL10
44 echinococcosis 9.8 CD40LG IL10
45 genital herpes 9.8 IL10 IL18
46 leptospirosis 9.8 CD40LG IL10
47 parasitic helminthiasis infectious disease 9.8 CD40LG IL10
48 acute graft versus host disease 9.8 IL10 IL18
49 secondary progressive multiple sclerosis 9.8 CD40LG IL10
50 upper respiratory tract disease 9.8 CD40LG IL10

Graphical network of the top 20 diseases related to Necrotizing Ulcerative Gingivitis:



Diseases related to Necrotizing Ulcerative Gingivitis

Symptoms & Phenotypes for Necrotizing Ulcerative Gingivitis

MGI Mouse Phenotypes related to Necrotizing Ulcerative Gingivitis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 BSG CD40LG CFB GUSB IL10 IL18
2 immune system MP:0005387 9.17 IL10 IL18 PTGES BSG CD40LG CFB

Drugs & Therapeutics for Necrotizing Ulcerative Gingivitis

Search Clinical Trials , NIH Clinical Center for Necrotizing Ulcerative Gingivitis

Cochrane evidence based reviews: gingivitis, necrotizing ulcerative

Genetic Tests for Necrotizing Ulcerative Gingivitis

Anatomical Context for Necrotizing Ulcerative Gingivitis

MalaCards organs/tissues related to Necrotizing Ulcerative Gingivitis:

38
Bone

Publications for Necrotizing Ulcerative Gingivitis

Articles related to Necrotizing Ulcerative Gingivitis:

(show top 50) (show all 105)
# Title Authors Year
1
Adjunct Use of Low-Level Laser Therapy on the Treatment of Necrotizing Ulcerative Gingivitis: A Case Report. ( 29399316 )
2018
2
Necrotizing Ulcerative Gingivitis. ( 29042743 )
2017
3
Unexpected Acute Necrotizing Ulcerative Gingivitis in a Well-controlled HIV-infected Case. ( 28781315 )
2017
4
Prevalence and treatment of necrotizing ulcerative gingivitis (NUG) in the British Armed Forces: a case-control study. ( 27830369 )
2016
5
Complete Genome Sequence for Treponema sp. OMZ 838 (ATCC 700772, DSM 16789), Isolated from a Necrotizing Ulcerative Gingivitis Lesion. ( 25540346 )
2014
6
Managing patients with necrotizing ulcerative gingivitis. ( 23763733 )
2013
7
Necrotizing ulcerative gingivitis and the orthodontic patient: a case series. ( 23524550 )
2013
8
Prevalence of necrotizing ulcerative gingivitis and associated factors in Koranic boarding schools in Senegal. ( 22779382 )
2012
9
The phylum Synergistetes in gingivitis and necrotizing ulcerative gingivitis. ( 22878253 )
2012
10
Necrotizing ulcerative gingivitis: a discussion of four dissimilar presentations. ( 22206178 )
2011
11
Images in emergency medicine. Acute necrotizing ulcerative gingivitis. ( 16492485 )
2006
12
Acute necrotizing ulcerative gingivitis and bacteremia caused by Stenotrophomonas maltophilia in an immunocompromised host. ( 15702051 )
2005
13
Inflammatory cytokine profile and circulating cortisol levels in malnourished children with necrotizing ulcerative gingivitis. ( 16266866 )
2005
14
Treponema putidum sp. nov., a medium-sized proteolytic spirochaete isolated from lesions of human periodontitis and acute necrotizing ulcerative gingivitis. ( 15280279 )
2004
15
The epidemiology, etiology, and pathophysiology of acute necrotizing ulcerative gingivitis associated with malnutrition. ( 15318254 )
2004
16
Gingival crevice microbiota from Chinese patients with gingivitis or necrotizing ulcerative gingivitis. ( 14871191 )
2004
17
Acute myelogenous leukemia complicated by acute necrotizing ulcerative gingivitis due to Aspergillus terreus. ( 12769350 )
2003
18
Oral pemphigoid masquerading as necrotizing ulcerative gingivitis in a child. ( 12083540 )
2002
19
Treponema parvum sp. nov., a small, glucoronic or galacturonic acid-dependent oral spirochaete from lesions of human periodontitis and acute necrotizing ulcerative gingivitis. ( 11411720 )
2001
20
Necrotizing ulcerative gingivitis. ( 10863376 )
1999
21
Acute necrotizing ulcerative gingivitis-periodontitis: a literature review. ( 9597852 )
1998
22
Human Herpesviridae in acute necrotizing ulcerative gingivitis in children in Nigeria. ( 9467378 )
1997
23
Necrotizing ulcerative gingivitis, periodontitis, and stomatitis: clinical staging and predisposing factors. ( 8558402 )
1995
24
Case #1. Acute necrotizing ulcerative gingivitis. ( 8619074 )
1995
25
Severity of necrotizing ulcerative gingivitis in Nigerian children. ( 9055679 )
1995
26
Acute necrotizing ulcerative gingivitis: risk factors involving host defense mechanisms. ( 9673175 )
1994
27
Oral hygiene status and necrotizing ulcerative gingivitis in Nigerian children. ( 8295093 )
1993
28
Serum IgG and IgM levels to bacterial antigens in necrotizing ulcerative gingivitis. ( 8463942 )
1993
29
The treatment of acute necrotizing ulcerative gingivitis. ( 2068255 )
1991
30
Acute necrotizing ulcerative gingivitis is associated with attachment loss. ( 1753002 )
1991
31
Pathogen-related spirochetes identified within gingival tissue from patients with acute necrotizing ulcerative gingivitis. ( 1855985 )
1991
32
Identification of spirochetes related to Treponema pallidum in necrotizing ulcerative gingivitis and chronic periodontitis. ( 1713299 )
1991
33
Acute necrotizing ulcerative gingivitis associated with von Willebrand's disease: a case report. ( 2150929 )
1990
34
The problem of the taxonomy of the fusiform bacillus of acute necrotizing ulcerative gingivitis (Vincent's gingivitis). ( 2196849 )
1990
35
Spirochetes in early lesions of necrotizing ulcerative gingivitis experimentally induced in beagles. ( 2087354 )
1990
36
Allelic variants for complement factors C3, C4, and B in acute necrotizing ulcerative gingivitis. ( 3163352 )
1988
37
Epidemiology of acute necrotizing ulcerative gingivitis. ( 3066627 )
1988
38
A case-control study of plasma ascorbate and acute necrotizing ulcerative gingivitis. ( 3163353 )
1988
39
Acute necrotizing ulcerative gingivitis: etiology and stress relationships. ( 3462166 )
1986
40
Peripheral blood phagocyte function in acute necrotizing ulcerative gingivitis. ( 2941561 )
1986
41
Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. ( 3514841 )
1986
42
Necrotizing ulcerative gingivitis in the military from ancient to modern times. ( 3935959 )
1985
43
Necrotizing ulcerative gingivitis in beagle dogs. III. Distribution of spirochetes in interdental gingival tissue. ( 2934537 )
1985
44
Acute necrotizing ulcerative gingivitis in a case of systemic lupus erythematosus. ( 3855317 )
1985
45
ABC's periodontics. "N" is for necrotizing ulcerative gingivitis. ( 3866022 )
1985
46
Acute necrotizing ulcerative gingivitis: a review. ( 6594833 )
1984
47
Necrotizing ulcerative gingivitis in beagle dogs. II. Histologic characteristics of NUG in relation to interproximal contacts. ( 6232372 )
1984
48
Acute necrotizing ulcerative gingivitis: clinical features, etiology and treatment. ( 6585327 )
1984
49
Necrotizing ulcerative gingivitis in beagle dogs. I. Attempts at unilateral induction and intraoral transmission of NUG, a microbiological and clinical study. ( 6232371 )
1984
50
Demographic and clinical data associated with acute necrotizing ulcerative gingivitis in a dental school population (ANUG-demographic and clinical data). ( 6592176 )
1984

Variations for Necrotizing Ulcerative Gingivitis

Expression for Necrotizing Ulcerative Gingivitis

Search GEO for disease gene expression data for Necrotizing Ulcerative Gingivitis.

Pathways for Necrotizing Ulcerative Gingivitis

Pathways related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.12 CFB IL10
2 11.05 CD40LG IL10
3 10.95 IL10 IL18
4 10.7 IL10 IL18
5 10.49 CD40LG IL10 IL18
6 10.36 CD40LG IL10 IL18

GO Terms for Necrotizing Ulcerative Gingivitis

Cellular components related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 CD40LG CFB GLA GUSB IL10 IL18
2 extracellular space GO:0005615 9.1 CD40LG CFB CTRL GUSB IL10 IL18

Biological processes related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 9.16 CD40LG IL10
2 negative regulation of nitric oxide biosynthetic process GO:0045019 8.96 GLA IL10
3 type 2 immune response GO:0042092 8.62 IL10 IL18

Molecular functions related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.13 CD40LG IL10 IL18
2 hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 8.62 GLA GUSB

Sources for Necrotizing Ulcerative Gingivitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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