MCID: NNT009
MIFTS: 52

Neonatal Diabetes Mellitus malady

Categories: Genetic diseases, Fetal diseases, Metabolic diseases, Rare diseases, Endocrine diseases

Aliases & Classifications for Neonatal Diabetes Mellitus

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Aliases & Descriptions for Neonatal Diabetes Mellitus:

Name: Neonatal Diabetes Mellitus 11 50 13 68
Neonatal Diabetes 24 27
 
Diabetes Mellitus Syndrome in Newborn Infant 11

Classifications:



External Ids:

Disease Ontology11 DOID:11717
ICD1030 P70.2
SNOMED-CT62 49817004
ICD9CM32 775.1
NCIt45 C99248

Summaries for Neonatal Diabetes Mellitus

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Wikipedia:71 Neonatal diabetes mellitus (NDM) is a monogenic form of diabetes that occurs in the first 6 months of... more...

MalaCards based summary: Neonatal Diabetes Mellitus, also known as neonatal diabetes, is related to diabetes mellitus, transient neonatal, 1 and diabetes mellitus, permanent neonatal. An important gene associated with Neonatal Diabetes Mellitus is ABCC8 (ATP Binding Cassette Subfamily C Member 8), and among its related pathways are Cori Cycle and Antiarrhythmic Pathway, Pharmacodynamics. Affiliated tissues include testes, pancreas and kidney, and related mouse phenotypes are shRNA abundance <= 50% and renal/urinary system.

Related Diseases for Neonatal Diabetes Mellitus

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Diseases in the Neonatal Diabetes Mellitus family:

Diabetes Mellitus, Transient Neonatal, 1 Diabetes Mellitus, Transient Neonatal 2
Diabetes Mellitus, Transient Neonatal, 3 Diabetes Mellitus, 6q24-Related Transient Neonatal
Abcc8-Related Transient Neonatal Diabetes Mellitus 2 Diabetes Mellitus, Kcnj11-Related Transient Neonatal

Diseases related to Neonatal Diabetes Mellitus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1diabetes mellitus, transient neonatal, 112.2
2diabetes mellitus, permanent neonatal12.2
3abcc8-related transient neonatal diabetes mellitus 212.0
4abcc8-related permanent neonatal diabetes mellitus12.0
5gck-related permanent neonatal diabetes mellitus12.0
6ins-related permanent neonatal diabetes mellitus12.0
7kcnj11-related permanent neonatal diabetes mellitus12.0
8pdx1-related permanent neonatal diabetes mellitus12.0
9diabetes mellitus, 6q24-related transient neonatal11.8
10diabetes mellitus, transient neonatal, 311.8
11pancreatic and cerebellar agenesis11.8
12diabetes mellitus, neonatal, with congenital hypothyroidism11.6
13diabetes mellitus, transient neonatal 211.6
14noonan syndrome 310.3ABCC8, KCNJ11
15diaphanospondylodysostosis10.2ABCC8, GCK
16x small rings10.2HYMAI, PLAGL1
17nosophobia10.2ABCC8, GCK, KCNJ11
18ritscher-schinzel syndrome 210.2ABCC8, KCNJ11
19chondroma10.2ABCC8, INS, KCNJ11
20exosc3-related pontocerebellar hypoplasia10.2HYMAI, PLAGL1, ZFP57
21antidepressant type abuse10.1GCK, INS, KCNJ11
22pancreatitis10.1
23labyrinthine unilateral reactive loss10.1ABCC8, GCK, INS, KCNJ11
24image syndrome10.1INS, KCNJ5
25fanconi renotubular syndrome 210.1ABCC8, PLAGL1, ZFP57
26alopecia-mental retardation syndrome 210.1ABCC8, INS, SLC2A2
27maturity-onset diabetes of the young, type 1310.1ABCC8, GCK, INS, KCNJ11
28orbital granuloma10.1GCK, PDX1
29diabetic cataract10.1ABCC8, GCK, INS, KCNJ11
30neurogenic arthropathy10.1ABCC8, GCK, INS, KCNJ11
31hemorrhagic fever10.1ABCC8, KCNJ11
32pancreatic agenesis10.0
33spondylocostal dysostosis 510.0HNF1B, SLC2A2
34autoimmune disease 110.0ABCC8, INS, KCNJ11, KCNJ5
35paroxysmal nonkinesigenic dyskinesia 210.0INS, NEUROD1
36interleukin 1 receptor antagonist deficiency10.0EIF2AK3, KCNJ5
37paternal uniparental disomy of chromosome 610.0
38macroglossia9.9
39peroneal neuropathy9.9ABCC8, GCK, INS, KCNJ11, SLC2A2
40body dysmorphic disorder9.9ABCC8, GCK, INS, KCNJ11, SLC2A2
41deafness, autosomal recessive 669.9ABCC8, HYMAI, INS, KCNJ11, PLAGL1, ZFP57
42exostosis9.9ABCC8, GCK, INS, KCNJ11, KCNJ5
43ischemic heart disease9.9ABCC8, GCK, INS, PDX1, SLC2A2
44non-syndromic intellectual disability9.8ABCC8, GCK, INS, KCNJ11, PDX1, PTF1A
45mosaic trisomy 139.8ABCC8, GCK, HNF1B, INS, KCNJ11, PDX1
46brain stem glioma9.8ABCC8, GCK, INS, KCNJ11, PDX1, SLC2A2
47wolcott-rallison syndrome9.8
48hepatitis9.8
49pearson syndrome9.8
50congenital hypothyroidism9.8

Graphical network of the top 20 diseases related to Neonatal Diabetes Mellitus:



Diseases related to neonatal diabetes mellitus

Symptoms & Phenotypes for Neonatal Diabetes Mellitus

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GenomeRNAi Phenotypes related to Neonatal Diabetes Mellitus according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00343-S6.7EIF2AK3, GCK, KCNJ11, KCNJ5, NEUROD1, PDX1

MGI Mouse Phenotypes related to Neonatal Diabetes Mellitus according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.9GCK, GLIS3, HNF1B, INS, NEUROD1, PDX1
2MP:00053708.4EIF2AK3, GCK, HNF1B, INS, PDX1, PTF1A
3MP:00030128.0ABCC8, EIF2AK3, GLIS3, INS, KCNJ11, PDX1
4MP:00053847.4EIF2AK3, GLIS3, INS, NEUROD1, PDX1, PLAGL1
5MP:00053796.8ABCC8, EIF2AK3, GCK, GLIS3, HNF1B, INS
6MP:00053766.8ABCC8, EIF2AK3, GCK, GLIS3, HNF1B, INS
7MP:00053786.8EIF2AK3, GCK, GLIS3, HNF1B, INS, KCNJ11
8MP:00107686.5EIF2AK3, GCK, GLIS3, HNF1B, INS, KCNJ11

Drugs & Therapeutics for Neonatal Diabetes Mellitus

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Drugs for Neonatal Diabetes Mellitus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 184)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
ZincapprovedPhase 4, Phase 2, Phase 322967440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
2
MetforminapprovedPhase 4, Phase 2, Phase 31803657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
3
Insulin LisproapprovedPhase 4240133107-64-9
Synonyms:
Insulin lispro (genetical recombination)
Insulin lispro (rDNA origin)
Insulin lispro protamine
 
Insulin lispro protamine recombinant
Insulin lispro recombinant
Insulin,lispro,human/rDNA
Insulin,lispro,protamine/rDNA
4
Insulin AspartapprovedPhase 4, Phase 3, Phase 2442116094-23-616132418
Synonyms:
(AspB28)-human insulin
1024611-56-0
116094-23-6
139532-40-4
28(sup B)-L-Aspartic acid-insulin (human)
877034-90-7
AspB28-insulin (human)
Aspart
Aspart Insulin
Aspart insulin
B28-Asp-insulin
B28-Aspart-Insulin
INA-X 14
 
INA-X14
Insulin X14
Insulin aspart
Insulin aspart [USAN]
Insulin aspart protamine recombinant
Insulin aspart recombinant
Insulin, Asp(B28)
LS-185932
NovoLog
NovoMix 30
NovoRapid
NovoRapid 30 Mix
Novolog mix 70/30
UNII-D933668QVX
5
GlyburideapprovedPhase 4, Phase 3, Phase 211410238-21-83488
Synonyms:
1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
10238-21-8
5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide
5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
AB00051949
AC1L1G1Q
AC1Q44V7
AKOS001487495
Abbenclamide
Adiab
Apo-Glibenclamide
Azuglucon
BIDD:GT0239
BPBio1_000344
BRD-K36927236-001-06-0
BRN 2230085
BSPBio_000312
BSPBio_001351
BSPBio_003053
Bastiverit
Benclamin
Betanase
Betanese 5
Bio-0156
Bio1_000076
Bio1_000565
Bio1_001054
Bio2_000071
Bio2_000551
C07022
C23H28ClN3O5S
CAS-10238-21-8
CBiol_001790
CHEBI:5441
CHEMBL472
CID3488
CPD000058229
Calabren
Cytagon
D00336
D005905
DB01016
Daonil
Debtan
Dia-basan
Diabeta
Diabeta (TN)
Diabiphage
Dibelet
DivK1c_000481
Duraglucon
EINECS 233-570-6
EU-0100499
Euclamin
Euglucan
Euglucon
Euglucon 5
Euglucon N
Euglykon
G 0639
G0639_SIAL
G0639_SIGMA
G2539_SIAL
GBN 5
Gen-Glybe
Gewaglucon
Gilemal
Glamide
Glibadone
Gliban
Gliben
Gliben-Puren N
Glibenbeta
Glibenclamid AL
Glibenclamid Basics
Glibenclamid Fabra
Glibenclamid Genericon
Glibenclamid Heumann
Glibenclamid Riker M
Glibenclamid Riker M.
Glibenclamid-Cophar
Glibenclamid-Ratiopharm
Glibenclamida
Glibenclamida [INN-Spanish]
Glibenclamide
Glibenclamide (JP15/INN)
Glibenclamidum
Glibenclamidum [INN-Latin]
Glibenil
Glibens
Glibesyn
Glibet
Glibetic
Glibil
Gliboral
Glicem
Glidiabet
Glimel
Glimide
Glimidstata
Glisulin
Glitisol
Glubate
Gluben
Gluco-Tablimen
Glucobene
Glucohexal
Glucolon
Glucomid
Glucoremed
Glucoven
Glyben
Glybenclamide
Glybenzcyclamide
Glyburide
Glyburide (USP)
Glyburide (micronized)
Glyburide [USAN]
 
Glycolande
Glycomin
Glynase
Glynase (TN)
HB 419
HB 420
HB-419
HB-420
HB419
HB420
HMS1361D13
HMS1568P14
HMS1791D13
HMS1922L08
HMS1989D13
HMS2089L06
HMS2093P04
HMS501I03
Hemi-Daonil
Hexaglucon
Humedia
I06-0716
IDI1_000481
IDI1_033821
KBio1_000481
KBio2_000071
KBio2_000730
KBio2_002639
KBio2_003298
KBio2_005207
KBio2_005866
KBio3_000141
KBio3_000142
KBio3_002273
KBioGR_000071
KBioGR_001897
KBioSS_000071
KBioSS_000730
LS-159295
Lederglib
Libanil
Lisaglucon
Lopac-G-0639
Lopac0_000499
MLS000069721
MLS001077262
Malix
Maninil
Med-Glionil
Melix
Micronase
Micronase (TN)
Micronized glyburide
Miglucan
MolPort-000-784-850
N-(4-(2-(5-Chloro-2-methoxybenzamido)ethyl)phenylsulfonyl)-N'-cyclohexylurea
N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N -cyclohexylurea
N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea
NCGC00015467-01
NCGC00015467-02
NCGC00015467-06
NCGC00015467-16
NCGC00016689-01
NCGC00023447-02
NCGC00023447-04
NCGC00023447-05
NCGC00023447-06
NCGC00023447-07
NCGC00023447-08
NCGC00023447-09
NCGC00023447-10
NCGC00023447-11
NCGC00023447-12
NINDS_000481
Nadib
Neogluconin
Norglicem 5
Normoglucon
Novo-Glyburide
Oprea1_764617
Orabetic
Pira
Praeciglucon
PresTab
Prestwick0_000316
Prestwick1_000316
Prestwick2_000316
Prestwick3_000316
Prestwick_569
Probes1_000431
Probes2_000378
Prodiabet
Renabetic
S1716_Selleck
SAM002564212
SMR000058229
SPBio_001831
SPBio_002531
SPECTRUM2300229
SR-01000000196-5
STK362992
Semi-Daonil
Semi-Euglucon
Semi-Gliben-Puren N
Semi-daonil
Spectrum2_001816
Spectrum3_001327
Spectrum4_001199
Spectrum5_001631
Spectrum_000250
Sugril
Suraben
Tiabet
Tocris-0911
U 26452
U-26452
UNII-SX6K58TVWC
UPCMLD-DP006
UPCMLD-DP006:001
UR 606
Yuglucon
ZINC00537805
glibenclamide
glyburide
6
ZidovudineapprovedPhase 449530516-87-135370
Synonyms:
-Azido-3&prime
-deoxythymidine
1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine
3&prime
3' Azido 2',3' Dideoxythymidine
3' Azido 3' deoxythymidine
3'-Azido-2',3'-Dideoxythymidine
3'-Azido-3'-deoxythymidine
3'-Azido-3'-deoxythymidine & Concanavalin A
3'-Azido-3'-deoxythymidine & Erythropoietin
3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19
3'-Azido-3'-deoxythymidine & Interleukin-1
3'-Azido-3'-deoxythymidine & Interleukin-2
3'-Azido-3'-deoxythymidine & Interleukin-6
3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6
3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon
3'-Azido-3'-deoxythymidine & Sho-Saiko-To
3'-Azido-3'-deoxythymidine (AIDS)
3'-Azido-3'deoxythymidine & Interferon .alpha.
3'-Azidothymidine
3'-Deoxy-3'-azidothymidine
3'-azido-3'-deoxythymidine, AZT
3-Azido-3-deoxythymidine
30516-87-1
399024-19-2
A2169_SIGMA
AC1L1TKL
AC1Q2OEK
AZT
AZT & CD4(178)-PE 40
AZT & Colony-stimulating factor 2
AZT & Concanavalin A (ConA)
AZT & EPO
AZT & GM-CSF
AZT & HPA
AZT & IFN.alpha.
AZT & IL-1
AZT & IL-2
AZT & IL-6
AZT & Interferon-.alpha.-2
AZT & Li & EPO
AZT & Li & GM-CSF
AZT & Li & IL-1
AZT & Li & IL-6
AZT & Lymphoblastoid Interferon
AZT & NP (from PHCA or HSA)
AZT & PM-19
AZT & SST
AZT & rIFN.alpha.2
AZT & rsCD4 & rIFN.alpha.A
AZT & rsT4
AZT & sCD4
AZT & srCD4
AZT (Antiviral)
AZT Antiviral
AZT TRANSPLACENTAL CARCINOGENESIS STUDY
AZT+PRO 140
AZT, Antiviral
Antiviral AZT
Apo-Zidovudine
Azidothymidine
Aztec
BB_NC-1012
BPBio1_000403
BRD-K72903603-001-04-6
BSPBio_000365
BSPBio_003153
BW A509U
BW-A 509U
BW-A-509U
BW-A509U
BWA 509U
BWA-509U
BWA509U
C07210
CCRIS 105
CHEBI:10110
CHEBI:127307
CHEMBL129
CID35370
 
CPD000058351
Compound S
Cpd S
D00413
D015215
DB00495
DRG-0004
DS-4152 & AZT
DivK1c_000524
HMS1921J20
HMS2090G11
HMS2092D06
HMS501K06
HSDB 6515
IDI1_000524
Interferon AD + 3'-azido-3'-deoxythymidine
Intron A & AZT
K7 [P Ti2 W10 O40]
KBio1_000524
KBio2_001828
KBio2_004396
KBio2_006964
KBio3_002653
KBioGR_000703
KBioSS_001828
LS-1159
Liposomal AZT-SN-1
Liposomal AZT-SN-3
MLS000028548
MLS001055351
MLS001076358
MLS002153202
MLS002222249
Met-SDF-1.beta. & AZT
Met-SDF-1.beta. & Zidovudine
MolPort-002-507-286
NCGC00023945-03
NCGC00023945-04
NCGC00023945-05
NCGC00023945-08
NCGC00178237-01
NCGC00178237-02
NINDS_000524
NSC 602670
Novo-Azt
PC-SOD+AZT
Prestwick3_000333
Propolis+AZT
Racemic Liposomal AZT
Retrovir
Retrovir (TN)
Retrovir(TM)
SAM002548971
SMR000058351
SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SPBio_000834
SPECTRUM1502109
STK801891
Spectrum2_000927
Spectrum3_001507
Spectrum4_000332
Spectrum5_001101
Spectrum_001348
UNII-4B9XT59T7S
ZDV
ZIDOVUDINE [AZT]
ZINC03779042
ZVD
Zidovudin
Zidovudina
Zidovudina [Spanish]
Zidovudine (JAN/USP/INN)
Zidovudine EP III
Zidovudine [USAN:INN:BAN:JAN]
Zidovudine+PRO 140
Zidovudinum
Zidovudinum [Latin]
antiviral
azidodeoxythymidine
rIFN-beta seron & AZT
racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
zidovudin
zidovudine
7
Gabapentinapproved, investigationalPhase 430360142-96-33446
Synonyms:
1-(Aminomethyl)-cyclohexaneacetic acid
1-(Aminomethyl)cyclohexaneacetic acid
2-[1-(aminomethyl)cyclohexyl]acetic acid
60142-96-3
AC-1485
AC1L1FYE
AC1Q53PH
AKOS000280865
Aclonium
Apo-Gabapentin
Apotex brand of gabapentin
Aventis brand of gabapentin
BB_SC-1512
BIDD:GT0656
BPBio1_000993
BRN 2359739
BSPBio_000901
C040029
C9H17NO2
CAS-60142-96-3
CCRIS 7210
CHEBI:188316
CHEBI:42797
CHEMBL940
CI 945
CI-945
CID3446
D00332
DB00996
DDS-2003
DM-1796
DM-5689
EINECS 262-076-3
EU-0100582
G-154
G0318
G154_SIGMA
GBN
GOE 2450
Gabapen
Gabapentin
Gabapentin (JAN/USAN/INN)
Gabapentin GR
Gabapentin Hexal
Gabapentin Stada
Gabapentin [USAN:INN:BAN]
Gabapentin-ratiopharm
Gabapentina
Gabapentine
Gabapentine [INN-French]
Gabapentino
Gabapentino [INN-Spanish]
Gabapentino [Spanish]
Gabapentinum
 
Gabapentinum [INN-Latin]
Gabapetin
Go 3450
Goe-3450
HMS1570N03
HMS2089J03
HSDB 7364
Hexal brand of gabapentin
I06-0677
L000733
LS-7194
Lopac-G-154
Lopac0_000582
MLS000069358
MolPort-000-883-862
NCGC00015466-01
NCGC00015466-02
NCGC00015466-06
NCGC00015466-09
NCGC00016891-01
NCGC00021545-02
NCGC00021545-04
NCGC00021545-05
NSC742194
Neurontin
Neurontin (TN)
Novo-Gabapentin
Novo-Gabapentine
Novopharm brand of gabapentin
PMS-Gabapentin
Parke Davis brand of gabapentin
Pfizer brand of gabapentin
Pharmascience brand of gabapentin
Prestwick0_000861
Prestwick1_000861
Prestwick2_000861
Prestwick3_000861
Prestwick_151
S2133_Selleck
SMR000058311
SPBio_002822
STK598009
Serada
Stadapharm brand of gabapentin
TL8003814
Tocris-0806
UNII-6CW7F3G59X
Vultin
Warner-Lambert brand of gabapentin
[1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID
gabapentin
gabapentin (Neurontin)
gabapentina
gabapentinium
ratiopharm brand of gabapentin
8
MisoprostolapprovedPhase 430459122-46-25282381
Synonyms:
(+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1 methyl ester
(11-alpha,13E)-(+-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester
59122-46-2
62015-39-8
AC1NQZZA
Ambap103601-27-0
BRN 4155643
CCRIS 6859
CHEMBL606
CID5282381
Cytotec
Cytotec (TN)
D00419
DB00929
GyMiso
HMS2090L10
HSDB 3573
I14-11712
Isprelor
 
M6807_SIGMA
MLS000028863
Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
Misopess
Misoprostol (JAN/USAN/INN)
Misoprostolum
Misoprostolum [INN-Latin]
Misotol
MolPort-003-666-830
NCGC00162445-01
NCGC00162445-02
SC 29333
SC-29333
SMP1_000193
SMR000058558
UNII-0E43V0BB57
XP-16J
methyl (11alpha,13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate
misoprostol
9
NevirapineapprovedPhase 4223129618-40-24463
Synonyms:
11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE
11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[2,3-e:3',2'-b][1,4]diazepin-6-one
11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[2,3-e:3',2'-b][1,4]diazepin-6-one & PRO 140 (Anti-CCR5 monoclonal antibody)
11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
129618-40-2
1vrt
2hny
AC-643
AC1L1I81
BI RG 587
BI-RG-587
BI-RG-587 & CD4-IgG
BIDD:GT0326
BIRG 0587
BIRG 587
BIRG-0587
BIRG-587
BIRG587
Bio-0789
C07263
C15H14N4O
CHEBI:44659
CHEMBL57
CID4463
CPD000048458
Cahill May Roberts Brand of Nevirapine
D00435
D019829
DB00238
DB08311
 
HMS2051J09
HSDB 7164
I02-0310
LS-2289
MLS000084585
MLS000759409
MLS001055309
MLS001201730
MolPort-002-507-817
N11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e]-[1,4]diazepin-6-one & CD4-immunoadhesin
NCGC00065890-02
NEV
NON-NUCLEOSIDE RT INHIBITOR NEVIRAPINE
NSC 641530
NSC641530
NVP
Nevirapine
Nevirapine & CD4-IgG
Nevirapine & PRO 140
Nevirapine (JAN/USP/INN)
Nevirapine [USAN:INN]
Promeco Brand of Nevirapine
S1742_Selleck
SAM001246551
SMR000048458
STK580320
UNII-99DK7FVK1H
Viramune
Viramune (TN)
Viramune(TM)
Viramune, BI-RG 587, Nevirapine
ZINC00004778
nevirapine
10
Folic Acidapproved, nutraceutical, vet_approvedPhase 4439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
11
leucovorinapproved, NutraceuticalPhase 4323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
12
Vitamin Capproved, nutraceuticalPhase 453150-81-75785, 54670067
Synonyms:
(+)-Sodium L-ascorbate
(+)-ascorbate
(+)-ascorbic acid
(2R)-2-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-furan-3-one
(2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
129940-97-2
134-03-2 (monosodium salt)
14536-17-5
154170-90-8
2-(1,2-Dihydroxyethyl)-4,5-dihydroxyfuran-3-one
255564_SIAL
259133-78-3
3-Keto-L-gulofuranolactone
3-Oxo-L-gulofuranolactone
3-Oxo-L-gulofuranolactone (enol form)
30208-61-8
33034_RIEDEL
33034_SIAL
47863_SUPELCO
47A605F0-4187-47A8-B0CE-F9E7DA1B0076
50-81-7
50976-75-5
56172-55-5
56533-05-2
57304-74-2
57606-40-3
623158-95-2
6730-29-6
882690-91-7
884381-69-5
885512-24-3
88845-26-5
89924-69-6
95209_FLUKA
95209_SIGMA
95210_FLUKA
95210_SIAL
95212_FLUKA
A0278_SIGMA
A0537
A2174_SIGMA
A2218_SIGMA
A2343_SIGMA
A4403_SIGMA
A4544_SIGMA
A5960_SIGMA
A7506_SIGMA
A92902_ALDRICH
A92902_SIAL
AB00376923
AB1002440
AC1L1L4T
AC1Q77S6
AR-1J3435
Acid Ascorbic
Acide ascorbique
Acide ascorbique [INN-French]
Acido ascorbico
Acido ascorbico [INN-Spanish]
Acidum ascorbicum
Acidum ascorbicum [INN-Latin]
Acidum ascorbinicum
Adenex
Allercorb
Ambap36431-82-0
Antiscorbic vitamin
Antiscorbutic factor
Antiscorbutic vitamin
Arco-cee
Ascoltin
Ascoltin (TN)
Ascor-B.I.D.
Ascorb
Ascorbajen
Ascorbate
Ascorbic Acid
Ascorbic Acid, Monosodium Salt
Ascorbic acid
Ascorbic acid (JP15/USP/INN)
Ascorbic acid [BAN:INN:JAN]
Ascorbic acid [INN:BAN:JAN]
Ascorbicab
Ascorbicap
Ascorbicap (TN)
Ascorbicin
Ascorbin
Ascorbinsaeure
Ascorbinsäure
Ascorbutina
Ascorbyl radical
Ascorin
Ascorteal
Ascorvit
BPBio1_000363
BSPBio_000329
C-Level
C-Long
C-Quin
C-Span
C-Vimin
C00072
C6H8O6
CCRIS 57
CE-VI-Sol
CHEBI:29073
CHEMBL196
CID5785
Cantan
Cantaxin
Caswell No. 061B
Catavin C
Ce lent
Ce-Mi-Lin
Ce-mi-lin
Ce-vi-sol
Cebicure
Cebid
Cebion
Cebione
Cecon
Cee-Caps TD
Cee-Vite
Cee-caps TD
Cee-vite
Cegiolan
Ceglion
Ceklin
Celaskon
Celin
Cell C
Cemagyl
Cemill
Cenetone
Cenolate
Cereon
Cergona
Cescorbat
Cetamid
Cetane
Cetane-Caps TC
Cetane-Caps TD
Cetane-caps TC
Cetane-caps TD
Cetebe
Cetemican
Cevalin
 
Cevatine
Cevex
Cevi-Bid
Cevi-bid
Cevimin
Cevital
Cevitamate
Cevitamic acid
Cevitamin
Cevitan
Cevitex
Cewin
Chewcee
Ciamin
Cipca
Citriscorb
Citrovit
Colascor
Concemin
Cortalex
D00018
DB00126
Davitamon C
Dora-C-500
Duoscorb
EINECS 200-066-2
FEMA No. 2109
Ferancee
Ferrous ascorbate
HSDB 818
HiCee
Hicee
Hybrin
IDO-C
Ido-C
Iron(II) ascorbate
Iron-ascorbic acid complexes
Juvamine
Kangbingfeng
Kyselina askorbova
Kyselina askorbova [Czech]
L(+)-Ascorbate
L(+)-Ascorbic acid
L-(+)-Ascorbate
L-(+)-Ascorbic Acid
L-(+)-Ascorbic acid
L-(+)-ascorbic acid
L-3-Ketothreohexuronic acid lactone
L-3-ketothreohexuronic acid
L-Ascorbate
L-Ascorbic Acid
L-Ascorbic acid
L-Ascorbic acid, free radical form
L-Lyxoascorbate
L-Lyxoascorbic acid
L-Threo-ascorbic acid
L-Threoascorbic acid
L-Xyloascorbate
L-Xyloascorbic acid
L-ascorbate
L-threo-Hex-2-enonic acid, gamma-lactone
L-threo-ascorbic acid
L-threo-hex-2-enono-1,4-lactone
LS-145
Laroscorbine
Lemascorb
Liqui-Cee
Liqui-cee
MLS002153776
Magnesium Ascorbicum
Magnorbin
Meri-C
Meri-c
MolPort-001-792-501
Monodehydroascorbic acid
NCGC00091517-01
NCGC00091517-02
NCGC00164357-01
NCI-C54808
NSC 33832
Natrascorb
Natrascorb injectable
Oral Vitamin C
Planavit C
Prestwick3_000325
Proscorbin
Redoxon
Ribena
Ronotec 100
Rontex 100
Roscorbic
Rovimix C
SMR001233160
Scorbacid
Scorbu C
Scorbu-C
Secorbate
Semidehydroascorbate
Sodascorbate
Sodium Ascorbate (Ascorbic Acid)
Stuartinic
Suncoat VC 40
Sunkist
Testascorbic
Tolfrinic
UNII-PQ6CK8PD0R
VASC
Vicelat
Vicin
Vicomin C
Viforcit
Viscorin
Viscorin 100M
Vitace
Vitacee
Vitacimin
Vitacin
Vitamin C
Vitamin- C
Vitamin-?C
Vitamisin
Vitascorbol
W210901_ALDRICH
Xitix
acide ascorbique
acidum ascorbicum
acidum ascorbinicum
antiscorbic vita min
ascor-b.i.d
ascorbate
ascorbic acid
bmse000182
cee-caps td
cevibid
component of Cortalex
component of E and C-Level
component of Endoglobin Forte
component of Ferancee
gamma-Lactone L-threo-Hex-2-enonate
gamma-Lactone L-threo-Hex-2-enonic acid
l-ascorbic acid
l-threo-hex-1-eofuranos-3-ulose
nchembio.174-comp5
nchembio.89-comp1
nchembio.92-comp2
nchembio821-comp9
roscorbi c
vitamin C
ácido ascórbico
13Gastrointestinal AgentsPhase 4, Phase 3, Phase 2, Early Phase 18402
14Hypoglycemic AgentsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 15896
15insulinPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 14646
16Trace ElementsPhase 4, Phase 3, Phase 16001
17MicronutrientsPhase 4, Phase 3, Phase 16001
18HematinicsPhase 41684
19Insulin, Globin ZincPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 14645
20Vitamin B ComplexPhase 44337
21VitaminsPhase 4, Phase 3, Phase 15282
22Anti-Infective AgentsPhase 4, Phase 222062
23AntimetabolitesPhase 4, Phase 212054
24Pharmaceutical SolutionsPhase 4, Phase 3, Phase 2, Phase 18192
25Insulin, Short-ActingPhase 4, Phase 3, Phase 292
26Protective AgentsPhase 4, Phase 37443
27AntioxidantsPhase 4, Phase 2, Phase 33050
28glucagonPhase 4, Phase 2, Phase 1, Early Phase 1478
29ProtaminesPhase 4, Phase 3181
30Glucagon-Like Peptide 1Phase 4, Phase 2, Phase 1, Early Phase 1715
31Isophane Insulin, HumanPhase 4, Phase 3, Phase 2151
32Isophane insulin, beefPhase 4, Phase 3, Phase 2151
33Insulin, IsophanePhase 4, Phase 3, Phase 2252
34Nucleic Acid Synthesis InhibitorsPhase 44962
35AntacidsPhase 41842
36Anti-Ulcer AgentsPhase 41842
37Reverse Transcriptase InhibitorsPhase 41913
38OxytocicsPhase 4707
39
SiliconPhase 41037440-21-34082203
Synonyms:
Si
 
Silica
Silicate
Silicic acid
40Cytochrome P-450 CYP3A InducersPhase 41119
41SulfalenePhase 484
42Anti-HIV AgentsPhase 43162
43Antiviral AgentsPhase 49967
44Anti-Retroviral AgentsPhase 43296
45InositolNutraceuticalPhase 487
46Vitamin B9NutraceuticalPhase 44392
47AcidophilusNutraceuticalPhase 4, Phase 3558
48FolateNutraceuticalPhase 44392
49BifidobacteriumNutraceuticalPhase 4247
50
DiazoxideapprovedPhase 2, Phase 322364-98-73019
Synonyms:
2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
364-98-7
7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian]
7-chloro-3-methyl-4H-1
AC1L1EZN
Aroglycem
BPBio1_000016
BRD-K73109821-001-05-2
BSPBio_000014
BSPBio_001307
BSPBio_002290
Bio1_000036
Bio1_000525
Bio1_001014
Bio2_000027
Bio2_000507
C06949
C8H7ClN2O2S
CAS-364-98-7
CBiol_001750
CHEBI:4495
CHEMBL181
CID3019
CPD000058392
D 9035
D00294
D003981
D9035_SIGMA
DB01119
Diazossido
Diazossido [DCIT]
Diazossido [Italian]
Diazoxide
Diazoxide (JAN/USP/INN)
Diazoxide [USAN:INN:BAN]
Diazoxido
Diazoxido [INN-Spanish]
Diazoxidum
Diazoxidum [INN-Latin]
Dizoxide
EINECS 206-668-1
EU-0100404
Eudemine
HMS1361B09
HMS1568A16
HMS1791B09
HMS1922L22
HMS1989B09
HMS2051P20
HMS2089L04
HMS2093N12
Hyperstat
Hyperstat (TN)
Hypertonalum
I06-2041
 
IDI1_033777
KBio2_000027
KBio2_002595
KBio2_005163
KBio3_000053
KBio3_000054
KBio3_001510
KBioGR_000027
KBioGR_001776
KBioSS_000027
LS-40410
Lopac-D-9035
Lopac0_000404
MLS000028459
MLS001076071
MolPort-003-666-772
MolPort-003-941-186
Mutabase
NCGC00015380-01
NCGC00015380-02
NCGC00015380-03
NCGC00015380-05
NCGC00015380-12
NCGC00024907-01
NCGC00024907-02
NCGC00024907-03
NCGC00024907-04
NCGC00024907-05
NCGC00024907-06
NCGC00024907-07
NCGC00024907-08
NSC 64198
NSC 76130
NSC-64198
NSC64198
NSC76130
Prestwick0_000087
Prestwick1_000087
Prestwick2_000087
Prestwick3_000087
Prestwick_163
Proglicem
Proglycem
SAM001246872
SMR000058392
SPBio_001953
SPECTRUM2300206
SRG 95213
SRG-95213
Sch 6783
Sch-6783
Spectrum3_000735
Spectrum4_001248
Tocris-0964
UNII-O5CB12L4FN
VU0239714-6
ZINC03872277
diazoxide
nchembio.150-comp49
nchembio.476-comp10

Interventional clinical trials:

(show top 50)    (show all 291)
idNameStatusNCT IDPhase
1Efficacy of Myo-inositol in Preventing Gestational Diabetes in High-risk Pregnant WomenUnknown statusNCT01511835Phase 4
2Antioxidants in Gestational DiabetesCompletedNCT02355197Phase 4
3Metformin Versus Insulin in Gestational DiabetesCompletedNCT01240785Phase 4
4Treatment of Mild Gestational Diabetes With Glyburide Versus PlaceboCompletedNCT00744965Phase 4
5A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes MellitusCompletedNCT01563120Phase 4
6Resistance Exercise Training During Pregnancy: a Randomized Controlled TrialCompletedNCT00813657Phase 4
7Lifestyle Intervention to Limit Excessive Weight Gain During Pregnancy in Minority WomenCompletedNCT01084941Phase 4
8DAME: Induction of Labor or Waiting for Suspicion Fetal MacrosomiaCompletedNCT00190320Phase 4
9Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled TrialRecruitingNCT02590016Phase 4
10Effect of Probiotics (Vivomixx®) on Weight, Microbiota and Glucose Tolerance in Obese Pregnant Women and Their NewbornRecruitingNCT02508844Phase 4
11Study of HIV-Infected and Uninfected Pregnant Woman/Child Dyads in Gabarone, BotawanaRecruitingNCT03088410Phase 4
12Preventing Recurrent Gestational Diabetes With MetforminRecruitingNCT02394158Phase 4
13Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness TrialRecruitingNCT02639429Phase 4
14Myo-Inositol- Based Co-treatment in Women With PCOS Undergoing Assisted Reproductive TechnologyRecruitingNCT03177122Phase 4
15A Study to Confirm the Long-term Safety and Effectiveness of Kalydeco in Patients With Cystic Fibrosis Who Have an R117H-CFTR Mutation, Including Pediatric PatientsActive, not recruitingNCT02722057Phase 4
16Long-Term Sulfonylurea Response in KCNJ11 Neonatal DiabetesEnrolling by invitationNCT02624817Phase 4
17Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR)Enrolling by invitationNCT02624830Phase 4
18Metabolic Analysis for Treatment Choice in Gestational Diabetes MellitusNot yet recruitingNCT03029702Phase 4
19Failure Rate of GLyburide And Metformin Among Gestational DiabeticsNot yet recruitingNCT03078725Phase 4
20Glyburide Compared to Insulin in the Management of White's Classification A2 Gestational DiabetesWithdrawnNCT00160485Phase 4
21Metformin Treatment in Gestational Diabetes and Noninsulin Dependent Diabetes in Pregnancy in a Developing CountryUnknown statusNCT01855763Phase 2, Phase 3
22A Randomized Clinical Trial of Oral Magnesium Supplementation in PregnancyUnknown statusNCT02032186Phase 3
23Diazoxide In the Management Of Hypoglycemic NeonatesUnknown statusNCT00994149Phase 2, Phase 3
24Probiotics (Lactobacillus Rhamnosus) in Reducing Glucose Intolerance During and After PregnancyUnknown statusNCT01436448Phase 3
25Glibentek in Patients With Neonatal Diabetes Secondary to Mutations in K+-ATP ChannelsCompletedNCT02375828Phase 3
26MAIN STUDY: Low Glycaemic Index (GI) Diet in the Management of GDM SUB-STUDY: The Breast Milk Sub-StudyCompletedNCT01589757Phase 2, Phase 3
27Efficacy of Behavioral Therapy and Exercise in Gestational Diabetes Mellitus (GDM)CompletedNCT01506310Phase 3
28Lifestyle Interventions for Expectant Mothers (LIFE-Moms Phoenix) - PhoenixCompletedNCT01812694Phase 3
29Metformin in Obese Non-diabetic Pregnant WomenCompletedNCT01273584Phase 2, Phase 3
30Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing EnterocolitisCompletedNCT00707785Phase 3
31Effect of Physical Activity on Metabolic Syndrome in Pregnancy & Fetal OutcomeCompletedNCT00647595Phase 3
32Efficacy and Safety of Insulin Detemir Versus Neutral Protamine Hagedorn (NPH) Insulin in Pregnant Women With Type 1 DiabetesCompletedNCT00474045Phase 3
33Diabetes Therapy to Improve BMI and Lung Function in CFCompletedNCT00072904Phase 3
34Early Diagnosis of Diabetes Mellitus in Patients With Cystic FibrosisCompletedNCT00662714Phase 3
35The Microvascular Complications StudyCompletedNCT00222508Phase 3
36Insulin Glargine Vs Standard Insulin TherapyCompletedNCT00222521Phase 3
37Behavioral Treatment of Weight Gain in CFCompletedNCT00006169Phase 3
38Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)CompletedNCT00099164Phase 3
39Behavioral & Nutritional Treatment to Help CF Preschoolers GrowCompletedNCT00241969Phase 3
40Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)RecruitingNCT02932475Phase 3
41Metformin in Women With Type 2 Diabetes in Pregnancy TrialRecruitingNCT01353391Phase 3
42Medico-GDM Trial - Metformine to Prevent Gestational Diabetes MellitusRecruitingNCT02275845Phase 3
43Modulation of the Intestinal Flora With the Probiotic VIVOMIXX™ in Pregnant Women at Risk of Metabolic ComplicationsRecruitingNCT02768818Phase 3
44Cystic Fibrosis - Insulin Deficiency, Early ActionRecruitingNCT01100892Phase 3
45A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation DisordersRecruitingNCT02336243Phase 3
46The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis PatientsRecruitingNCT02496780Phase 2, Phase 3
47Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational DiabetesActive, not recruitingNCT01731431Phase 3
48Effect of a Continuous Glucose Monitoring on Maternal and Neonatal Outcomes in Gestational Diabetes MellitusNot yet recruitingNCT02838147Phase 3
49A Clinical Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes MellitusNot yet recruitingNCT02980276Phase 3
50Glycemic Objectives of Women With Gestational Diabetes MellitusTerminatedNCT02478762Phase 3

Search NIH Clinical Center for Neonatal Diabetes Mellitus

Genetic Tests for Neonatal Diabetes Mellitus

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Genetic tests related to Neonatal Diabetes Mellitus:

id Genetic test Affiliating Genes
1 Neonatal Diabetes Mellitus27
2 Neonatal Diabetes24

Anatomical Context for Neonatal Diabetes Mellitus

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MalaCards organs/tissues related to Neonatal Diabetes Mellitus:

36
Testes, Pancreas, Kidney, Heart, Brain

Publications for Neonatal Diabetes Mellitus

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Articles related to Neonatal Diabetes Mellitus:

(show top 50)    (show all 216)
idTitleAuthorsYear
1
Case report: maternal mosaicism resulting in inheritance of a novel GATA6 mutation causing pancreatic agenesis and neonatal diabetes mellitus. (28049534)
2017
2
Decreases in Gap Junction Coupling Recovers Ca2+ and Insulin Secretion in Neonatal Diabetes Mellitus, Dependent on Beta Cell Heterogeneity and Noise. (27681078)
2016
3
Age-Adjusted Glycated Albumin at Diagnosis is more Correlated with the Product of Age and Plasma Glucose than Plasma Glucose Alone in Patients with Neonatal Diabetes Mellitus. (27121214)
2016
4
Successful treatment of young infants presenting neonatal diabetes mellitus with continuous subcutaneous insulin infusion before genetic diagnosis. (26831749)
2016
5
Molecular and clinical features of KATP -channel neonatal diabetes mellitus in Japan. (27681997)
2016
6
Successful transition to sulfonylurea therapy in two Iraqi siblings with neonatal diabetes mellitus and iDEND syndrome due to ABCC8 mutation. (27849623)
2016
7
The functional activity of hypothalamic signaling systems in rats with neonatal diabetes mellitus treated with metformin. (27193707)
2016
8
Incidence, prevalence and genetic determinants of neonatal diabetes mellitus: a systematic review and meta-analysis protocol. (27832816)
2016
9
Glycemic control indicator levels at diagnosis of neonatal diabetes mellitus: Comparison with other types of insulin-dependent diabetes mellitus. (27995726)
2016
10
Genetic Analysis and Follow-Up of 25 Neonatal Diabetes Mellitus Patients in China. (26839896)
2016
11
Differentiating Transient Idiopathic Hyperglycaemia and Neonatal Diabetes Mellitus in Preterm Infants. (25998132)
2015
12
Neonatal diabetes mellitus due to a novel mutation in the GATA6 gene accompanying renal dysfunction: A case report. (25708516)
2015
13
A Novel Mitochondrial DNA Deletion in a Patient with Pearson Syndrome and Neonatal Diabetes Mellitus Provides Insight into Disease Etiology, Severity and Progression. (26518169)
2015
14
Sulfonylurea in the treatment of neonatal diabetes mellitus children with heterogeneous genetic backgrounds. (25781672)
2015
15
Role of ZAC1 in transient neonatal diabetes mellitus and glucose metabolism. (26322169)
2015
16
Successful sulfonylurea treatment in a patient with permanent neonatal diabetes mellitus with a novel KCNJ11 mutation. (26388896)
2015
17
Gene Variants Associated with Transient Neonatal Diabetes Mellitus in the Very Low Birth Weight Infant. (26315042)
2015
18
Age-adjusted glycated albumin accurately reflects blood glucose in patients with neonatal diabetes mellitus: comparison with calculated glycated albumin determined by past blood glucose concentrations. (25977574)
2015
19
Permanent neonatal diabetes mellitus - a case report of a rare cause of diabetes mellitus in East Africa. (26958039)
2015
20
Transient Neonatal Diabetes Mellitus followed by recurrent asymptomatic hypoglycaemia: a case report. (26631065)
2015
21
Paediatric endocrinology: Paradigm shift in genetic testing for neonatal diabetes mellitus-new framework for clinical care. (26284444)
2015
22
A novel SNP in 3' UTR of INS gene: A case report of neonatal diabetes mellitus. (26212367)
2015
23
A case of a Japanese patient with neonatal diabetes mellitus caused by a novel mutation in the ABCC8 gene and successfully controlled with oral glibenclamide. (26568660)
2015
24
Neonatal Hyperglycemia due to Transient Neonatal Diabetes Mellitus in Puerto Rico. (26576310)
2015
25
A new compound heterozygosis for inactivating mutations in the glucokinase gene as cause of permanent neonatal diabetes mellitus (PNDM) in double-first cousins. (26587058)
2015
26
Letter to the editor: recent advances in genetic testing and treatment of neonatal diabetes mellitus. (25559538)
2015
27
A novel mitochondrial DNA deletion in a patient with Pearson syndrome and neonatal diabetes mellitus provides insight into disease etiology, severity and progression. (26016877)
2015
28
Permanent neonatal diabetes mellitus in Jordan. (24825091)
2014
29
Permanent neonatal diabetes mellitus in China. (25052923)
2014
30
Deciphering a molecular mechanism of neonatal diabetes mellitus by the chemical synthesis of a protein diastereomer, [D-AlaB8]human proinsulin. (25002580)
2014
31
A novel mutation of KCNJ11 gene in a patient with permanent neonatal diabetes mellitus. (24468099)
2014
32
Microscopic and ultrastructural features in Wolcott-Rallison syndrome, a permanent neonatal diabetes mellitus: about two autopsy cases. (25131821)
2014
33
Glycemic control indicators in patients with neonatal diabetes mellitus. (24748932)
2014
34
A novel activating ABCC8 mutation underlying neonatal diabetes mellitus in an infant presenting with cerebral sinovenous thrombosis. (24468609)
2014
35
Clinical utility gene card for: Transient Neonatal Diabetes Mellitus, 6q24-related. (24569603)
2014
36
Permanent neonatal diabetes mellitus in monozygotic twins achieving low-dose sulfonylurea therapy. (23959658)
2014
37
HbA1c can be a useful glycemic control marker for patients with neonatal diabetes mellitus older than 20 weeks of age. (24854496)
2014
38
Chromosome 6q24 transient neonatal diabetes mellitus and protein sensitive hyperinsulinaemic hypoglycaemia. (24859512)
2014
39
6q24 transient neonatal diabetes mellitus: the first case report from China. (25316252)
2014
40
Relapsing 6q24-related transient neonatal diabetes mellitus successfully treated with a dipeptidyl peptidase-4 inhibitor: a case report. (24552466)
2014
41
Permanent neonatal diabetes mellitus due to an ABCC8 mutation: a case report. (24618446)
2014
42
Treatment of transient neonatal diabetes mellitus: insulin pump or insulin glargine? Our experience. (25437016)
2014
43
Insulin pump therapy in transient neonatal diabetes mellitus. (24904869)
2013
44
KCNJ11 in-frame 15-bp deletion leading to glibenclamide-responsive neonatal diabetes mellitus in a Chinese child. (24266052)
2013
45
Genetics of neonatal diabetes mellitus. (23456590)
2013
46
Age-adjusted glycated albumin: a more robust parameter to establish glycaemic control in neonatal diabetes mellitus. (24337793)
2013
47
KCNJ11 in-frame 15-bp deletion leading to glibenclamide- responsive neonatal diabetes mellitus in a Chinese child. (23640936)
2013
48
Transient neonatal diabetes mellitus in a Turkish patient with three novel homozygous variants in the ZFP57 gene. (23748067)
2013
49
Permanent neonatal diabetes mellitus: prevalence and genetic diagnosis in the SEARCH for Diabetes in Youth Study. (23050777)
2013
50
EIF2AK3 mutations in South Indian children with permanent neonatal diabetes mellitus associated with Wolcott-Rallison syndrome. (24168455)
2013

Variations for Neonatal Diabetes Mellitus

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Clinvar genetic disease variations for Neonatal Diabetes Mellitus:

5
id Gene Variation Type Significance SNP ID Assembly Location
1INSNM_ 000207.2(INS): c.127T> G (p.Cys43Gly)SNVPathogenicrs80356666GRCh37Chr 11, 2182075: 2182075
2INS; INS-IGF2NM_ 000207.2(INS): c.94G> A (p.Gly32Ser)SNVPathogenicrs80356664GRCh37Chr 11, 2182108: 2182108
3ABCC8NM_ 000352.4(ABCC8): c.394T> G (p.Phe132Val)SNVPathogenicrs80356637GRCh37Chr 11, 17491666: 17491666
4ABCC8NM_ 000352.4(ABCC8): c.3545G> A (p.Arg1182Gln)SNVPathogenic/ Likely pathogenicrs193922400GRCh37Chr 11, 17426071: 17426071

Expression for genes affiliated with Neonatal Diabetes Mellitus

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Search GEO for disease gene expression data for Neonatal Diabetes Mellitus.

Pathways for genes affiliated with Neonatal Diabetes Mellitus

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Pathways related to Neonatal Diabetes Mellitus according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathwaysScoreTop Affiliating Genes
19.9INS, SLC2A2
29.6ABCC8, KCNJ11, KCNJ5
3
Show member pathways
9.6ABCC8, KCNJ11, KCNJ5
4
Show member pathways
9.6ABCC8, KCNJ11, KCNJ5
5
Show member pathways
9.4ABCC8, INS, KCNJ11, SLC2A2
6
Show member pathways
8.8ABCC8, GCK, INS, KCNJ11, PDX1, SLC2A2
78.8ABCC8, GCK, INS, KCNJ11, PDX1, SLC2A2
8
Show member pathways
8.4GCK, HNF1B, INS, NEUROD1, PDX1, SLC2A2
98.2HNF1B, INS, NEUROD1, PDX1, PTF1A, SLC2A2
10
Show member pathways
7.9GCK, HNF1B, INS, NEUROD1, PDX1, PTF1A
11
Show member pathways
7.9GCK, HNF1B, INS, NEUROD1, PDX1, PTF1A
12
Show member pathways
7.9ABCC8, GCK, HNF1B, INS, KCNJ11, NEUROD1

GO Terms for genes affiliated with Neonatal Diabetes Mellitus

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Cellular components related to Neonatal Diabetes Mellitus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ATP-sensitive potassium channel complexGO:000828210.5ABCC8, KCNJ11
2voltage-gated potassium channel complexGO:00080769.6ABCC8, KCNJ11, KCNJ5

Biological processes related to Neonatal Diabetes Mellitus according to GeneCards Suite gene sharing:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of insulin secretionGO:004667610.8ABCC8, KCNJ11
2cellular glucose homeostasisGO:000167810.7ABCC8, GCK
3negative regulation of gluconeogenesisGO:004572110.7GCK, INS
4positive regulation of glycogen biosynthetic processGO:004572510.7GCK, INS
5detection of glucoseGO:005159410.6GCK, PDX1
6potassium ion importGO:001010710.6KCNJ11, KCNJ5
7exocrine pancreas developmentGO:003101710.5PDX1, PTF1A
8pancreas developmentGO:003101610.5PDX1, PTF1A
9negative regulation of type B pancreatic cell apoptotic processGO:200067510.4NEUROD1, PDX1
10nitric oxide mediated signal transductionGO:000726310.4NEUROD1, PDX1
11potassium ion transportGO:000681310.4ABCC8, KCNJ11, KCNJ5
12glucose transportGO:001575810.4GCK, INS, SLC2A2
13amacrine cell differentiationGO:003588110.3NEUROD1, PTF1A
14positive regulation of protein localization to nucleusGO:190018210.2EIF2AK3, INS
15glucose metabolic processGO:000600610.1GCK, INS, KCNJ11, PDX1
16response to glucoseGO:000974910.0HNF1B, NEUROD1, PDX1
17hindbrain developmentGO:00309029.9HNF1B, NEUROD1, PTF1A
18glucose homeostasisGO:00425939.9GCK, INS, NEUROD1, PDX1
19endocrine pancreas developmentGO:00310189.6EIF2AK3, NEUROD1, PDX1
20regulation of insulin secretionGO:00507969.6ABCC8, GCK, KCNJ11, NEUROD1, SLC2A2
21response to drugGO:00424939.5ABCC8, HNF1B, KCNJ11, NEUROD1, PDX1
22insulin secretionGO:00300739.3EIF2AK3, HNF1B, NEUROD1, PDX1
23positive regulation of transcription from RNA polymerase II promoterGO:00459448.7GLIS3, HNF1B, NEUROD1, PDX1, PLAGL1, PTF1A
24transcription from RNA polymerase II promoterGO:00063668.3GLIS3, NEUROD1, PDX1, PLAGL1, PTF1A
25regulation of transcription, DNA-templatedGO:00063558.1GLIS3, HNF1B, INS, NEUROD1, PDX1, PLAGL1

Molecular functions related to Neonatal Diabetes Mellitus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ATP-activated inward rectifier potassium channel activityGO:001527210.7ABCC8, KCNJ11
2inward rectifier potassium channel activityGO:00052429.8KCNJ11, KCNJ5
3DNA bindingGO:00036778.0GLIS3, HNF1B, NEUROD1, PDX1, PLAGL1, PTF1A

Sources for Neonatal Diabetes Mellitus

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet